Praeludium et fuga VII

Thesis (M.M.)--Boston Universit

Chlordane movement during rainfall

Indoor rainfall simulation experiments were conducted to quantify the mass of technical chlordane leaving an experimental soil box in runoff, splash and leachate. The initial mass of technical chlordane was uniformly distributed throughout the soil at concentrations equal to those recommended for termite control around basement and foundation walls. Two silt loam soils and one sandy soil were studied. The mass of chlordane in runoff adsorbed to organic matter was estimated to be 16 times the mass of chlordane in runoff adsorbed to clay. For a soil with a clay-to-organic-matter ratio as high as 66, the mass of chlordane in runoff appears to be predominantly a function of clay content. For a soil with a clay-to-organic-matter ratio as low as 2 to 5, the mass of chlordane in runoff appears to be predominantly a function of organic matter content. An increase in rainfall intensity from 51 to 102 mm/hr increased chlordane mass in runoff by 300 to 500 percent. This increase in rainfall intensity increased the chlordane-to-sediment mass ratio in the runoff by 7 to 18 percent. The chlordane mass in runoff was 5 to 9 times as great as the mass of bromide in runoff. The chlordane mass in splash was 25 percent of the chlordane mass in runoff. Only the sandy soil at the higher rainfall intensity produced leachate. The chlordane mass in this leachate during the rainfall period was 37 percent of the chlordane mass in runoff and 264 percent of the chlordane mass in splash. The total chlordane mass which left the soil box by runoff, splash and leachate was equivalent to 4 to 44 mg per square foot of treated surface. This amounted to 0.03 to 0.31 percent of the original chlordane mass applied to the experimental soil box. This could potentially occur from previous legal surface applications in agriculture and turf management, from more recent illegal surface applications in agriculture and turf management, from proper use (according to label directions) as a subsurface termiticide but where depth of untreated cover soil was insufficient, from improper use as a subsurface termiticide where treated soil remained uncovered at the surface or from disturbance by new construction of large areas treated in previous years. This type of horizontal movement of chlordane and other organochlorine pesticides has been documented. Bennett et al. (1974) measured 70 ppb of gamma chlordane in the top five inches of soil located 10 feet away from a foundation wall treated 21 years earlier. Lichtenstein (1958) found higher concentrations of the organochlorine insecticides aldrin, lindane and DDT on the downslope side than on the upslope side of treated test plots. Similarly, Peach et al. (1973) found surface movement of aldrin, lindane and heptachlor toward points of lower elevation in a sloping field. Haan (1971) conducted laboratory rainfall-runoff experiments following surface treatment with aldrin, dieldrin and DDT and found that sediment carried more than twice as much pesticide mass as the water. Wauchope (1978) reviewed the literature on pesticide losses in runoff water from agricultural fields. He found that organochlorine pesticides lose about 1 percent of the total mass applied to the field through runoff. This compared to other commercial pesticides which lose 0.5 percent or less unless severe rainfall conditions occur within 2 weeks after application. Another important consideration is the mass of pesticide located within a few millimeters of the soil surface. Investigators have found that it is this zone from which pesticides are released during rainfall. Sharpley (1985) studied 5 soils and found the depth of this zone to range from 2 to 4 mm for 4 percent slopes under 50 mm/hr rainfall intensity to 13 to 37 mm for 20 percent slopes under 160 mm/hr rainfall intensity.Project # G-1432-04 Agreement # 14-08-0001-G-1423-0

Concert recording 2017-11-27

[Track 1]. Concert prelude / Derek Bourgeois -- [Track 2]. Tuba concerto / Edward Gregson -- [Track 3]. Cyberspace / Peter Graham -- [Track 4]. Concert piece no. 1 / Rodger Vaughan -- [Track 5]. Rhapsody for euphonium / Jerry Brubaker -- [Track 6]. Concerto, K. 191. I. Allegro / W.A. Mozart -- [Track 7]. The green hill / Bert Appermont -- [Track 8]. Suite / Vaclav Nelhybel -- [Track 9]. Brides of the waves / Herbert L. Clarke -- [Track 10]. Fantasy / Philip Sparke -- [Track 11]. Concerto for euphonium. I. Allegro moderato / Philip Wilby

Concert recording 2018-04-24b

[Track 1]. Six studies in English folksong. I. Adagio [Track 2]. II. Andante sostenuto [Track 3]. III. Andante tranquillo [Track 4]. IV. Allegro vivace / Ralph Vaughan Williams -- [Track 5]. Sonata in F minor. I. Andante [Track 6]. II. Allegro / G.F. Teleman -- [Track 7]. Allerseelen / Richard Strauss arranged by Stuckemeyer/Bottorf -- [Track 8]. Bride of the waves / Herbert L. Clarke -- [Track 9]. Suite. I. Allegor marcato [Track 10]. III. Allegretto [Track 11]. IV. Slow / Vaclav Nelhybel -- [Track 12]. A walk in the woods / Jiro Censhu -- [Track 13]. Concerto in one movement / Alexy Lebedev -- [Track 14]. By gaslight / Tadeusz Kassatti -- [Track 15]. Child\u27s play. I. ♩=132 / Barbara York

Concert recording 2017-11-28

[Track 1]. Bill Bailey / Hughie Cannon arranged by James Garrett -- [Track 2]. Second suite. I. March [Track 3]. II. Song without words, I\u27ll love my love / Gustav Holst arranged by Cody Hutchison -- [Track 4]. Deutschland uber alles / Franz Joseph Haydn arranged by Eugene Anderson -- [Track 5]. Geleit from Three pieces / Johannes Brahms translated by William R. Lee -- [Track 6]. Belle of Chicago march / John Philip Sousa arranged by Skip Gray -- [Track 7]. Three preludes from op. 34. No. 14 [Track 8]. No. 7 [Track 9]. No. 16 / Dmitri Shostakovich arranged by Rauch -- [Track 10]. Tuba Sunday / traditional arranged by Gerald Sloan -- [Track 11]. Quartet for tubas / Sy Brandon -- [Track 12.] Cherokee / John Schooley -- [Track 13]. Moondance / John Stevens -- [Track 14]. Amazing grace / traditional arranged by David Uber

Discovery of common and rare genetic risk variants for colorectal cancer.

To further dissect the genetic architecture of colorectal cancer (CRC), we performed whole-genome sequencing of 1,439 cases and 720 controls, imputed discovered sequence variants and Haplotype Reference Consortium panel variants into genome-wide association study data, and tested for association in 34,869 cases and 29,051 controls. Findings were followed up in an additional 23,262 cases and 38,296 controls. We discovered a strongly protective 0.3% frequency variant signal at CHD1. In a combined meta-analysis of 125,478 individuals, we identified 40 new independent signals at P < 5 × 10-8, bringing the number of known independent signals for CRC to ~100. New signals implicate lower-frequency variants, Krüppel-like factors, Hedgehog signaling, Hippo-YAP signaling, long noncoding RNAs and somatic drivers, and support a role for immune function. Heritability analyses suggest that CRC risk is highly polygenic, and larger, more comprehensive studies enabling rare variant analysis will improve understanding of biology underlying this risk and influence personalized screening strategies and drug development.Goncalo R Abecasis has received compensation from 23andMe and Helix. He is currently an employee of Regeneron Pharmaceuticals. Heather Hampel performs collaborative research with Ambry Genetics, InVitae Genetics, and Myriad Genetic Laboratories, Inc., is on the scientific advisory board for InVitae Genetics and Genome Medical, and has stock in Genome Medical. Rachel Pearlman has participated in collaborative funded research with Myriad Genetics Laboratories and Invitae Genetics but has no financial competitive interest

Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements