Masstigio: o marketing no atual mercado de luxo

O mercado de luxo é o tema central desta monografia. O segmento cresceu consideravelmente nos últimos anos e a presente pesquisa tem o objetivo de investigar a transformação que vem ocorrendo nesse mercado aparentemente tão exclusivo. O foco do estudo recai principalmente sobre uma nova tendência de consumo que alguns especialistas de marketing batizaram de “Masstígio”. Esse fenômeno fez surgir uma série de novos aspectos no mercado de luxo, afetando diretamente o marketing das principais empresas. O Brasil desponta como um dos principais mercados do mundo. O crescente aumento de empresas estrangeiras em nosso país confirma o fascínio do consumidor brasileiro pelos produtos e serviços de luxo. O que o luxo representa hoje, entendê-lo como um segmento de negócio e analisar a gestão de marketing de algumas marcas tradicionais serão considerações abordadas no decorrer da pesquisa

Excess mortality attributed to heat and cold: a health impact assessment study in 854 cities in Europe

MCC Collaborative Research Network: Souzana Achilleos (Department of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus), Jan Kyselý (Institute of Atmospheric Physics, Academy of Sciences of the Czech Republic, Prague, Czech Republic), Ene Indermitte (Department of Family Medicine and Public Health, University of Tartu, Tartu, Estonia), Jouni J K Jaakkola and Niilo Ryti (Center for Environmental and Respiratory Health Research, and Medical Research Center Oulu, Oulu University Hospital, University of Oulu, Oulu, Finland), Mathilde Pascal (Santé Publique France, Department of Environmental Health, French National Public Health Agency, Saint Maurice, France), Antonis Analitis (Department of Hygiene, Epidemiology and Medical Statistics, National and Kapodistrian University of Athens, Athens, Greece), Klea Katsouyanni (School of Population Health and Environmental Sciences, King’s College, London, UK), Patrick Goodman (Technological University Dublin, Dublin, Ireland), Ariana Zeka (Institute for the Environment, Brunel University London, London, UK), Paola Michelozzi (Department of Epidemiology, Lazio Regional Health Service, Rome, Italy), Danny Houthuijs and Caroline Ameling (National Institute for Public Health and the Environment, Centre for Sustainability and Environmental Health, Bilthoven, Netherlands), Shilpa Rao (Norwegian institute of Public Health, Oslo, Norway), Susana das Neves Pereira da Silva and Joana Madureira (Department of Epidemiology, Instituto Nacional de Saúde Dr Ricardo Jorge, Lisbon, Portugal), Iulian-Horia Holobaca (Faculty of Geography, Babes-Bolay University, Cluj-Napoca, Romania), Aurelio Tobias (Institute of Environmental Assessment and Water Research, Spanish Council for Scientific Research, Barcelona, Spain), Carmen Íñiguez (Department of Statistics and Computational Research, Universitat de València, València, Spain), Bertil Forsberg (Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden), and Martina S Ragettli (Swiss Tropical and Public Health Institute, Basel, Switzerland).Online publication has been corrected. Correction available online 2 July 2024 https://doi.org/10.1016/S2542-5196(23)00171-7Background: Heat and cold are established environmental risk factors for human health. However, mapping the related health burden is a difficult task due to the complexity of the associations and the differences in vulnerability and demographic distributions. In this study, we did a comprehensive mortality impact assessment due to heat and cold in European urban areas, considering geographical differences and age-specific risks. Methods: We included urban areas across Europe between Jan 1, 2000, and Dec 12, 2019, using the Urban Audit dataset of Eurostat and adults aged 20 years and older living in these areas. Data were extracted from Eurostat, the Multi-country Multi-city Collaborative Research Network, Moderate Resolution Imaging Spectroradiometer, and Copernicus. We applied a three-stage method to estimate risks of temperature continuously across the age and space dimensions, identifying patterns of vulnerability on the basis of city-specific characteristics and demographic structures. These risks were used to derive minimum mortality temperatures and related percentiles and raw and standardised excess mortality rates for heat and cold aggregated at various geographical levels. Findings: Across the 854 urban areas in Europe, we estimated an annual excess of 203 620 (empirical 95% CI 180 882-224 613) deaths attributed to cold and 20 173 (17 261-22 934) attributed to heat. These corresponded to age-standardised rates of 129 (empirical 95% CI 114-142) and 13 (11-14) deaths per 100 000 person-years. Results differed across Europe and age groups, with the highest effects in eastern European cities for both cold and heat. Interpretation: Maps of mortality risks and excess deaths indicate geographical differences, such as a north-south gradient and increased vulnerability in eastern Europe, as well as local variations due to urban characteristics. The modelling framework and results are crucial for the design of national and local health and climate policies and for projecting the effects of cold and heat under future climatic and socioeconomic scenarios.Funding: The study was funded by Medical Research Council of the UK (MR/V034162/1 and MR/R013349/1), the Natural Environment Research Council UK (NE/R009384/1), the EU’s Horizon 2020 (820655), and the EU’s Joint Research Center (JRC/SVQ/2020/MVP/1654). AU and JK were supported by the Czech Science Foundation (22–24920S). VH has received funding from the EU’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement (101032087).info:eu-repo/semantics/publishedVersio

Self-exciting threshold binomial autoregressive processes

We introduce a new class of integer-valued self-exciting threshold models, which is based on the binomial autoregressive model of order one as introduced by McKenzie (Water Resour Bull 21:645–650, 1985. doi:10.1111/j.1752-1688.1985. tb05379.x). Basic probabilistic and statistical properties of this class of models are discussed. Moreover, parameter estimation and forecasting are addressed. Finally, the performance of these models is illustrated through a simulation study and an empirical application to a set of measle cases in Germany

Excess mortality attributed to heat and cold: a health impact assessment study in 854 cities in Europe

Data sharing: The exposure-response functions derived in this analysis, full results, and intermediary data are publicly available in a Zenodo repository (https://doi.org/10.5281/zenodo.7672108). The associated R code to reproduce the analysis is available in the corresponding author's GitHub page (https://github.com/pierremasselot). The mortality data have been obtained through a restricted data use agreement with each national institute and are therefore not available for public dissemination.Copyright © 2023 The Authors. Background: Heat and cold are established environmental risk factors for human health. However, mapping the related health burden is a difficult task due to the complexity of the associations and the differences in vulnerability and demographic distributions. In this study, we did a comprehensive mortality impact assessment due to heat and cold in European urban areas, considering geographical differences and age-specific risks. Methods: We included urban areas across Europe between Jan 1, 2000, and Dec 12, 2019, using the Urban Audit dataset of Eurostat and adults aged 20 years and older living in these areas. Data were extracted from Eurostat, the Multi-country Multi-city Collaborative Research Network, Moderate Resolution Imaging Spectroradiometer, and Copernicus. We applied a three-stage method to estimate risks of temperature continuously across the age and space dimensions, identifying patterns of vulnerability on the basis of city-specific characteristics and demographic structures. These risks were used to derive minimum mortality temperatures and related percentiles and raw and standardised excess mortality rates for heat and cold aggregated at various geographical levels. Findings: Across the 854 urban areas in Europe, we estimated an annual excess of 203 620 (empirical 95% CI 180 882–224 613) deaths attributed to cold and 20 173 (17 261–22 934) attributed to heat. These corresponded to age-standardised rates of 129 (empirical 95% CI 114–142) and 13 (11–14) deaths per 100 000 person-years. Results differed across Europe and age groups, with the highest effects in eastern European cities for both cold and heat. Interpretation: Maps of mortality risks and excess deaths indicate geographical differences, such as a north–south gradient and increased vulnerability in eastern Europe, as well as local variations due to urban characteristics. The modelling framework and results are crucial for the design of national and local health and climate policies and for projecting the effects of cold and heat under future climatic and socioeconomic scenarios.Medical Research Council of UK, the Natural Environment Research Council UK, the EU's Horizon 2020, and the EU's Joint Research Center. The study was funded by Medical Research Council of the UK (MR/V034162/1 and MR/R013349/1), the Natural Environment Research Council UK (NE/R009384/1), the EU's Horizon 2020 (820655), and the EU's Joint Research Center (JRC/SVQ/2020/MVP/1654). AU and JK were supported by the Czech Science Foundation (22–24920S). VH has received funding from the EU's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement (101032087

A multi-country test of brief reappraisal interventions on emotions during the COVID-19 pandemic.

The COVID-19 pandemic has increased negative emotions and decreased positive emotions globally. Left unchecked, these emotional changes might have a wide array of adverse impacts. To reduce negative emotions and increase positive emotions, we tested the effectiveness of reappraisal, an emotion-regulation strategy that modifies how one thinks about a situation. Participants from 87 countries and regions (n = 21,644) were randomly assigned to one of two brief reappraisal interventions (reconstrual or repurposing) or one of two control conditions (active or passive). Results revealed that both reappraisal interventions (vesus both control conditions) consistently reduced negative emotions and increased positive emotions across different measures. Reconstrual and repurposing interventions had similar effects. Importantly, planned exploratory analyses indicated that reappraisal interventions did not reduce intentions to practice preventive health behaviours. The findings demonstrate the viability of creating scalable, low-cost interventions for use around the world

Anti-promastigote Activity of the Amazon Plants

Universidade Federal do Pará. Programa de Pós-Graduação em Ciências Farmacêuticas. Belém, PA, Brasil.Universidade Federal do Pará. Programa de Pós-Graduação em Ciências Farmacêuticas. Belém, PA, Brasil.Universidade Federal do Pará. Programa de Pós-Graduação em Ciências Farmacêuticas. Belém, PA, Brasil.Universidade Federal do Pará. Programa de Pós-Graduação em Inovação Farmacêutica. Belém, PA, Brasil.Universidade Federal do Pará. Faculdade de Ciências Farmacêuticas. Belém, PA, Brasil.Universidade Federal do Pará. Faculdade de Ciências Farmacêuticas. Belém, PA, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.Universidade Federal do Pará. Faculdade de Química. Belém, PA, Brasil.Universidade Federal do Pará. Programa de Pós-Graduação em Ciências Farmacêuticas. Belém, PA, Brasil / Universidade Federal do Pará. Programa de Pós-Graduação em Inovação Farmacêutica. Belém, PA, Brasil.This study evaluated in vitro activity of ethanol extract, fractions, and isolated substance from Amazon species against promastigotes of L. amazonensis. The ethanol extracts were concentrated and fractionation. The anti-promastigote activity was evaluated through the cell viability assessment method (MTT). The ethanol extract, fractions, and isolated substance from Himatanthus articulatus and Parahancornia fasciculata were inactive in promastigote of L. amazonensis, as the ethanol extract of Physalis angulata. The hexane fractions from different parts of Montrichardia linifera showed anti-promastigote activity probably due to the presence of steroids and terpenes. All species in studies were inactive, except of M. linifera. The few polar constituents can be responsible for the activity. Therefore, the isolation and purification of the active on L. amazonensis promastigotes are urgently required