Environmental Impact Assessment: Detecting Changes in Fish Community Structure in Response to Disturbance with an Asymmetric Multivariate BACI Sampling Design

One of the primary challenges to detecting anthropogenic environmental impacts is the high degree of spatial and temporal variability inherent in natural systems. Planned or routine events that result in disturbance to populations and communities provide an opportunity for scientists to apply well-replicated and statistically powerful sampling designs to assess subsequent biological effects. For example, a thick layer of sessile invertebrates is the prominent biotic feature of intertidal and shallow subtidal portions of offshore petroleum platforms in southern California. Given the central role of such invertebrates in providing food and shelter, their presence can reasonably be expected to influence associated fish community structure. At one platform on the San Pedro Shelf, invertebrate biomass was completely removed from support pilings and horizontal crossmembers to a depth of 20 m with high-pressure water during a standard “hydrocleaning” event in November 2007. Three nearby platforms remained undisturbed, providing a unique opportunity to test for disturbance-related changes in the local fish assemblage and the overall time course of community recovery. The potential impact of the abrupt and intense removal of the invertebrate layer was assessed with survey data collected periodically for one year prior- and one year post-hydrocleaning in a modified Before-After-Control-Impact (BACI) design. Asymmetrical multivariate analyses of variance revealed a significant effect of disturbance to fish, driven largely by reductions in the abundance of numerically dominant blacksmith (Chromis punctipinnis). Nevertheless, the system was surprisingly resilient, recovering to pre-disturbance conditions within ten months. Our results demonstrate that a well-replicated BACI sampling design can detect even subtle biological changes in response to disturbance, a key step towards developing a mechanistic understanding of community disassembly in the face of increasingly frequent and intense perturbations

Trends in heavy metals, polychlorinated biphenyls and toxicity from sediment cores of the inner River Thames estuary, London, UK

River islands (Ait or Eyot) within the inner tidal Thames serve as unique recorders of current and historical estuarine chemical pollution. Sediment cores from Chiswick Ait were assessed for contamination using Microtox® solid phase bioassay, stable isotopes (δ13C, δ15N), heavy metals and polychlorinated biphenyls (PCBs). Microtox® classified these sediments as non-toxic to moderately toxic and bulk isotopes identified a change in organic input. Metals Cu, Zn, Cr, Ni, Cd, Hg and Ag showed parallel rise, peak and fall profiles which when allied to a 207/208Pb and 137Cs based chronology supported major changes in trace metal contributions corresponding to approximate input times of 1940 (rise), 1963 (peak) and 1985 (fall). Metals ranged from Cu 15 to 373 mg kg−1 (mean 141 mg kg−1), Zn 137 to 1331 mg kg−1 (mean 576 mg kg−1), Cr 14–351 mg kg−1 (mean 156 mg kg−1), Pb 10 to 1506 mg kg−1 (mean 402 mg kg−1), As 1 to 107 (mean 38 mg kg−1), Ni 11 to 113 mg kg−1 (mean 63 mg kg−1), Cd 0.2 to 53 mg kg−1 (mean 9 mg kg−1), Hg 1 to 8 mg kg−1 (mean 4.6 mg kg−1) and Ag from 0.7 to 50 mg kg−1 (mean 7.5 mg kg−1). Down core total PCBs ranged from 10.5 to 121 μg kg−1 and mean of 39 μg kg−1. The rise, peak and fall of Cu, Zn, Cr, Ni, Cd and Ag pollution matched local sewage works' treatment discharge records. Whereas the Hg, Pb and As profiles were disconnected, reflecting alternative historic sources and or partitioning behaviour. Comparison to marine sediment quality guidelines indicate that Zn, Pb, Ni, Cd and Hg exceed action level 2, whereas sedimentary Cu, Cr and As concentrations were above action level 1 (no action) but below action level 2 (further investigation required). The river islands of the tidal Thames capture a unique contaminant chemistry record due in part to their location in the tidal frame (salinity minimum) and close proximity to west London

Cosmological Perturbations Through a General Relativistic Bounce

The ekpyrotic and cyclic universe scenarios have revived the idea that the density perturbations apparent in today's universe could have been generated in a `pre-singularity' epoch before the big bang. These scenarios provide explicit mechanisms whereby a scale invariant spectrum of adiabatic perturbations may be generated without the need for cosmic inflation, albeit in a phase preceding the hot big bang singularity. A key question they face is whether there exists a unique prescription for following perturbations through the bounce, an issue which is not yet definitively settled. This goal of this paper is more modest, namely to study a bouncing Universe model in which neither General Relativity nor the Weak Energy Condition is violated. We show that a perturbation which is pure growing mode before the bounce does not match to a pure decaying mode perturbation after the bounce. Analytical estimates of when the comoving curvature perturbation varies around the bounce are given. It is found that in general it is necessary to evaluate the evolution of the perturbation through the bounce in detail rather than using matching conditions.Comment: 15 pages, 6 figures. Added more details showing how and when the comoving curvature perturbation varies on large scales during the bounc

LSST: from Science Drivers to Reference Design and Anticipated Data Products

(Abridged) We describe here the most ambitious survey currently planned in the optical, the Large Synoptic Survey Telescope (LSST). A vast array of science will be enabled by a single wide-deep-fast sky survey, and LSST will have unique survey capability in the faint time domain. The LSST design is driven by four main science themes: probing dark energy and dark matter, taking an inventory of the Solar System, exploring the transient optical sky, and mapping the Milky Way. LSST will be a wide-field ground-based system sited at Cerro Pach\'{o}n in northern Chile. The telescope will have an 8.4 m (6.5 m effective) primary mirror, a 9.6 deg$^2$ field of view, and a 3.2 Gigapixel camera. The standard observing sequence will consist of pairs of 15-second exposures in a given field, with two such visits in each pointing in a given night. With these repeats, the LSST system is capable of imaging about 10,000 square degrees of sky in a single filter in three nights. The typical 5$\sigma$ point-source depth in a single visit in $r$ will be $\sim 24.5$ (AB). The project is in the construction phase and will begin regular survey operations by 2022. The survey area will be contained within 30,000 deg$^2$ with $\delta<+34.5^\circ$, and will be imaged multiple times in six bands, $ugrizy$, covering the wavelength range 320--1050 nm. About 90\% of the observing time will be devoted to a deep-wide-fast survey mode which will uniformly observe a 18,000 deg$^2$ region about 800 times (summed over all six bands) during the anticipated 10 years of operations, and yield a coadded map to $r\sim27.5$. The remaining 10\% of the observing time will be allocated to projects such as a Very Deep and Fast time domain survey. The goal is to make LSST data products, including a relational database of about 32 trillion observations of 40 billion objects, available to the public and scientists around the world.Comment: 57 pages, 32 color figures, version with high-resolution figures available from https://www.lsst.org/overvie

The British Army, information management and the First World War revolution in military affairs

Information Management (IM) – the systematic ordering, processing and channelling of information within organisations – forms a critical component of modern military command and control systems. As a subject of scholarly enquiry, however, the history of military IM has been relatively poorly served. Employing new and under-utilised archival sources, this article takes the British Expeditionary Force (BEF) of the First World War as its case study and assesses the extent to which its IM system contributed to the emergence of the modern battlefield in 1918. It argues that the demands of fighting a modern war resulted in a general, but not universal, improvement in the BEF’s IM techniques, which in turn laid the groundwork, albeit in embryonic form, for the IM systems of modern armies. KEY WORDS: British Army, Information Management, First World War, Revolution in Military Affairs, Adaptatio

Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases

Central corneal thickness (CCT) is a highly heritable trait associated with complex eye diseases such as keratoconus and glaucoma. We perform a genome-wide association meta-analysis of CCT and identify 19 novel regions. In addition to adding support for known connective tissue-related pathways, pathway analyses uncover previously unreported gene sets. Remarkably, >20% of the CCT-loci are near or within Mendelian disorder genes. These included FBN1, ADAMTS2 and TGFB2 which associate with connective tissue disorders (Marfan, Ehlers-Danlos and Loeys-Dietz syndromes), and the LUM-DCN-KERA gene complex involved in myopia, corneal dystrophies and cornea plana. Using index CCT-increasing variants, we find a significant inverse correlation in effect sizes between CCT and keratoconus (r =-0.62, P = 5.30 × 10-5) but not between CCT and primary open-angle glaucoma (r =-0.17, P = 0.2). Our findings provide evidence for shared genetic influences between CCT and keratoconus, and implicate candidate genes acting in collagen and extracellular matrix regulation

Complement component C4 structural variation and quantitative traits contribute to sex-biased vulnerability in systemic sclerosis

Altres ajuts: Fondo Europeo de Desarrollo Regional (FEDER), "A way of making Europe".Copy number (CN) polymorphisms of complement C4 play distinct roles in many conditions, including immune-mediated diseases. We investigated the association of C4 CN with systemic sclerosis (SSc) risk. Imputed total C4, C4A, C4B, and HERV-K CN were analyzed in 26,633 individuals and validated in an independent cohort. Our results showed that higher C4 CN confers protection to SSc, and deviations from CN parity of C4A and C4B augmented risk. The protection contributed per copy of C4A and C4B differed by sex. Stronger protection was afforded by C4A in men and by C4B in women. C4 CN correlated well with its gene expression and serum protein levels, and less C4 was detected for both in SSc patients. Conditioned analysis suggests that C4 genetics strongly contributes to the SSc association within the major histocompatibility complex locus and highlights classical alleles and amino acid variants of HLA-DRB1 and HLA-DPB1 as C4-independent signals

Novel genetic loci associated with hippocampal volume

The hippocampal formation is a brain structure integrally involved in episodic memory, spatial navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal volume and shape are found in several common neuropsychiatric disorders. To identify the genetic underpinnings of hippocampal structure here we perform a genome-wide association study (GWAS) of 33,536 individuals and discover six independent loci significantly associated with hippocampal volume, four of them novel. Of the novel loci, three lie within genes (ASTN2, DPP4 and MAST4) and one is found 200 kb upstream of SHH. A hippocampal subfield analysis shows that a locus within the MSRB3 gene shows evidence of a localized effect along the dentate gyrus, subiculum, CA1 and fissure. Further, we show that genetic variants associated with decreased hippocampal volume are also associated with increased risk for Alzheimer's disease (rg =-0.155). Our findings suggest novel biological pathways through which human genetic variation influences hippocampal volume and risk for neuropsychiatric illness

Measurement of the mass difference between top quark and antiquark in pp collisions at root s=8 TeV

Peer reviewe