Motivacoes, contradicoes e ambiguidades na lideranca de enfermeiros em cargo de chefia num hospital universitario

OBJETIVO: analizar las contradicciones y ambigüedades que permean la motivación de enfermeros para el ejercicio del liderazgo en cargo de jefatura, en un hospital universitario. MÉTODO: aproximación cualitativa, exploratorio-descriptiva, totalizando 33 entrevistas semiestructuradas, sometidas al análisis temático. RESULTADOS: las informaciones convergieron para cinco categorías: Motivación para asumir cargo de jefatura; La mirada de las jefaturas de enfermería sobre el ejercicio del liderazgo; El aspecto emblemático de trabajar con las personas; Liderazgo en enfermería - mediadora y conciliadora; El tiempo: un dilema entre administrar y asistir. CONCLUSIÓN: liderar personas ora es un gran estímulo, ora un aspecto dificultador, ante los matices del trabajo en equipo y la complejidad del contexto en el que se construye ese proceso. Además, las actitudes conciliadoras y de mediación se mostraron fundamentales para un clima organizacional sano y productivo. Sin embargo, la falta de tiempo fue indicada como un dilema entre administrar y asistir.OBJETIVO: analisar as contradições e ambiguidades que perpassam a motivação de enfermeiros para o exercício da liderança em cargo de chefia, em um hospital universitário. MÉTODO: abordagem qualitativa, exploratório-descritiva, totalizando 33 entrevistas semiestruturadas, submetidas à análise temática. RESULTADOS: as informações convergiram para cinco categorias: motivação para assumir cargo de chefia; o olhar das chefias de enfermagem sobre o exercício da liderança; a face emblemática de trabalhar com as pessoas; liderança em enfermagem - mediadora e conciliadora, e o tempo: um dilema entre gerenciar e assistir. CONCLUSÃO: liderar pessoas ora é um grande estímulo ora se torna um aspecto dificultador, tendo em vista as nuances do trabalho em equipe e a complexidade do contexto no qual se constrói esse processo. Além disso, as atitudes conciliadoras e de mediação mostraram-se primordiais para um clima organizacional saudável e produtivo, no entanto, a falta de tempo foi apontada como um dilema entre gerenciar e assistir.OBJECTIVE: to analyze the contradictions and ambiguities which permeate nurses' motivation for exercising leadership in management positions, in a university hospital. METHOD: this study has a qualitative approach and is exploratory and descriptive, and used a total of 33 semi-structured interviews which were submitted to thematic analysis. RESULTS: the information converged on five categories: Motivation to take on a management position; The view of nursing managers on the exercising of leadership; The emblematic aspect of working with people; Leadership in nursing - mediatory and conciliatory; Time: a dilemma between managing and caring. CONCLUSION: leading people can be both a great encouragement, and an impeding aspect, bearing in mind the nuances of teamwork and the complexity of the context in which this process is constructed. In addition to this, conciliatory and mediatory attitudes are shown to be fundamental for a healthy and productive organizational atmosphere; however, the lack of time was indicated as a dilemma between managing and caring

Analysis of shared heritability in common disorders of the brain

ience, this issue p. eaap8757 Structured Abstract INTRODUCTION Brain disorders may exhibit shared symptoms and substantial epidemiological comorbidity, inciting debate about their etiologic overlap. However, detailed study of phenotypes with different ages of onset, severity, and presentation poses a considerable challenge. Recently developed heritability methods allow us to accurately measure correlation of genome-wide common variant risk between two phenotypes from pools of different individuals and assess how connected they, or at least their genetic risks, are on the genomic level. We used genome-wide association data for 265,218 patients and 784,643 control participants, as well as 17 phenotypes from a total of 1,191,588 individuals, to quantify the degree of overlap for genetic risk factors of 25 common brain disorders. RATIONALE Over the past century, the classification of brain disorders has evolved to reflect the medical and scientific communities' assessments of the presumed root causes of clinical phenomena such as behavioral change, loss of motor function, or alterations of consciousness. Directly observable phenomena (such as the presence of emboli, protein tangles, or unusual electrical activity patterns) generally define and separate neurological disorders from psychiatric disorders. Understanding the genetic underpinnings and categorical distinctions for brain disorders and related phenotypes may inform the search for their biological mechanisms. RESULTS Common variant risk for psychiatric disorders was shown to correlate significantly, especially among attention deficit hyperactivity disorder (ADHD), bipolar disorder, major depressive disorder (MDD), and schizophrenia. By contrast, neurological disorders appear more distinct from one another and from the psychiatric disorders, except for migraine, which was significantly correlated to ADHD, MDD, and Tourette syndrome. We demonstrate that, in the general population, the personality trait neuroticism is significantly correlated with almost every psychiatric disorder and migraine. We also identify significant genetic sharing between disorders and early life cognitive measures (e.g., years of education and college attainment) in the general population, demonstrating positive correlation with several psychiatric disorders (e.g., anorexia nervosa and bipolar disorder) and negative correlation with several neurological phenotypes (e.g., Alzheimer's disease and ischemic stroke), even though the latter are considered to result from specific processes that occur later in life. Extensive simulations were also performed to inform how statistical power, diagnostic misclassification, and phenotypic heterogeneity influence genetic correlations. CONCLUSION The high degree of genetic correlation among many of the psychiatric disorders adds further evidence that their current clinical boundaries do not reflect distinct underlying pathogenic processes, at least on the genetic level. This suggests a deeply interconnected nature for psychiatric disorders, in contrast to neurological disorders, and underscores the need to refine psychiatric diagnostics. Genetically informed analyses may provide important "scaffolding" to support such restructuring of psychiatric nosology, which likely requires incorporating many levels of information. By contrast, we find limited evidence for widespread common genetic risk sharing among neurological disorders or across neurological and psychiatric disorders. We show that both psychiatric and neurological disorders have robust correlations with cognitive and personality measures. Further study is needed to evaluate whether overlapping genetic contributions to psychiatric pathology may influence treatment choices. Ultimately, such developments may pave the way toward reduced heterogeneity and improved diagnosis and treatment of psychiatric disorders

Motivations, contradictions and ambiguities in the leadership of nurses in management positions in a university hospital

OBJECTIVE: to analyze the contradictions and ambiguities which permeate nurses' motivation for exercising leadership in management positions, in a university hospital. METHOD: this study has a qualitative approach and is exploratory and descriptive, and used a total of 33 semi-structured interviews which were submitted to thematic analysis. RESULTS: the information converged on five categories: Motivation to take on a management position; The view of nursing managers on the exercising of leadership; The emblematic aspect of working with people; Leadership in nursing - mediatory and conciliatory; Time: a dilemma between managing and caring. CONCLUSION: leading people can be both a great encouragement, and an impeding aspect, bearing in mind the nuances of teamwork and the complexity of the context in which this process is constructed. In addition to this, conciliatory and mediatory attitudes are shown to be fundamental for a healthy and productive organizational atmosphere; however, the lack of time was indicated as a dilemma between managing and caring

Fatores Associados aos Triggers e Eventos Adversos em Pediatria

Objetivo: verificar os fatores associados aos triggers e eventos adversos na internação pediátrica, Material e Método: pesquisa transversal embasada na metodologia do Institute for Healthcare Improvement (IHI), por meio da aplicação do Paediatric Trigger Tool (PTT) a uma amostra (n=194) de prontuários de pacientes pediátricos de um hospital do Centro-Oeste do Brasil. Foi realizada análise estatística descritiva, inferencial e regressão de Poisson. Resultados: mais da metade (n=107; 55,15%) dos pacientes apresentou pelo menos um trigger na internação. Foram identificados 204 triggers/gatilhos, com maior ocorrência de queda de hemoglobina/hematócrito (9,80%), queda de saturação de oxigênio (9,80%) e aumento de marcadores de funções renais (9,20%). Do total de gatilhos, 64 (31,37%) eventos adversos foram confirmados, os quais foram classificados majoritariamente como dano temporário com necessidade de suporte ao paciente (65,62%). O tempo de internação (p-valor=0,004) e o caráter da internação (p-valor<0,001) foram variáveis associadas à ocorrência de triggers. Caráter de internação e admissões provenientes de outras instituições foram preditores na ocorrência de triggers e eventos adversos. Discussão: O estudo encontrou 31,37% dos triggers resultando em danos ao paciente, a detecção precoce é essencial na segurança do paciente pediátrico, internações prolongadas estão ligadas a infecções e eventos adversos, transferências de pacientes exigem medidas de segurança rigorosas e eficazes. Conclusões: internações prolongadas e crianças admitidas via transferência merecem atenção a triggers e/ou eventos adversos concretizados.Objetivo: verificar os fatores associados aos triggers e eventos adversos na internação pediátrica, Material e Método: pesquisa transversal embasada na metodologia do Institute for Healthcare Improvement (IHI), por meio da aplicação do Paediatric Trigger Tool (PTT) a uma amostra (n=194) de prontuários de pacientes pediátricos de um hospital do Centro-Oeste do Brasil. Foi realizada análise estatística descritiva, inferencial e regressão de Poisson. Resultados: mais da metade (n=107; 55,15%) dos pacientes apresentou pelo menos um trigger na internação. Foram identificados 204 triggers/gatilhos, com maior ocorrência de queda de hemoglobina/hematócrito (9,80%), queda de saturação de oxigênio (9,80%) e aumento de marcadores de funções renais (9,20%). Do total de gatilhos, 64 (31,37%) eventos adversos foram confirmados, os quais foram classificados majoritariamente como dano temporário com necessidade de suporte ao paciente (65,62%). O tempo de internação (p-valor=0,004) e o caráter da internação (p-valor<0,001) foram variáveis associadas à ocorrência de triggers. Caráter de internação e admissões provenientes de outras instituições foram preditores na ocorrência de triggers e eventos adversos. Discussão: O estudo encontrou 31,37% dos triggers resultando em danos ao paciente, a detecção precoce é essencial na segurança do paciente pediátrico, internações prolongadas estão ligadas a infecções e eventos adversos, transferências de pacientes exigem medidas de segurança rigorosas e eficazes. Conclusões: internações prolongadas e crianças admitidas via transferência merecem atenção a triggers e/ou eventos adversos concretizados

Motivations, contradictions and ambiguities in the leadership of nurses in management positions in a university hospital

OBJECTIVE: to analyze the contradictions and ambiguities which permeate nurses' motivation for exercising leadership in management positions, in a university hospital. METHOD: this study has a qualitative approach and is exploratory and descriptive, and used a total of 33 semi-structured interviews which were submitted to thematic analysis. RESULTS: the information converged on five categories: Motivation to take on a management position; The view of nursing managers on the exercising of leadership; The emblematic aspect of working with people; Leadership in nursing - mediatory and conciliatory; Time: a dilemma between managing and caring. CONCLUSION: leading people can be both a great encouragement, and an impeding aspect, bearing in mind the nuances of teamwork and the complexity of the context in which this process is constructed. In addition to this, conciliatory and mediatory attitudes are shown to be fundamental for a healthy and productive organizational atmosphere; however, the lack of time was indicated as a dilemma between managing and caring

Effect of Intraoperative High Positive End-Expiratory Pressure (PEEP) With Recruitment Maneuvers vs Low PEEP on Postoperative Pulmonary Complications in Obese Patients: A Randomized Clinical Trial (vol 321, pg 2292, 2019)

status: publishe

Effect of Intraoperative High Positive End-Expiratory Pressure (PEEP) With Recruitment Maneuvers vs Low PEEP on Postoperative Pulmonary Complications in Obese Patients: A Randomized Clinical Trial.

IMPORTANCE An intraoperative higher level of positive end-expiratory positive pressure (PEEP) with alveolar recruitment maneuvers improves respiratory function in obese patients undergoing surgery, but the effect on clinical outcomes is uncertain

Effect of intraoperative high Positive End-Expiratory Pressure (PEEP) with recruitment maneuvers vs low PEEP on postoperative pulmonary complications in obese patients : a randomized clinical trial

IMPORTANCE An intraoperative higher level of positive end-expiratory positive pressure (PEEP) with alveolar recruitment maneuvers improves respiratory function in obese patients undergoing surgery, but the effect on clinical outcomes is uncertain. OBJECTIVE To determine whether a higher level of PEEP with alveolar recruitment maneuvers decreases postoperative pulmonary complications in obese patients undergoing surgery compared with a lower level of PEEP. DESIGN, SETTING, AND PARTICIPANTS Randomized clinical trial of 2013 adults with body mass indices of 35 or greater and substantial risk for postoperative pulmonary complications who were undergoing noncardiac, nonneurological surgery under general anesthesia. The trial was conducted at 77 sites in 23 countries from July 2014-February 2018; final follow-up: May 2018. INTERVENTIONS Patients were randomized to the high level of PEEP group (n = 989), consisting of a PEEP level of 12 cm H2O with alveolar recruitment maneuvers (a stepwise increase of tidal volume and eventually PEEP) or to the low level of PEEP group (n = 987), consisting of a PEEP level of 4 cm H2O. All patients received volume-controlled ventilation with a tidal volume of 7 mL/kg of predicted body weight. MAIN OUTCOMES AND MEASURES The primary outcomewas a composite of pulmonary complications within the first 5 postoperative days, including respiratory failure, acute respiratory distress syndrome, bronchospasm, new pulmonary infiltrates, pulmonary infection, aspiration pneumonitis, pleural effusion, atelectasis, cardiopulmonary edema, and pneumothorax. Among the 9 prespecified secondary outcomes, 3 were intraoperative complications, including hypoxemia (oxygen desaturation with SpO(2) 1 minute). RESULTS Among 2013 adults who were randomized, 1976 (98.2%) completed the trial (mean age, 48.8 years; 1381 [69.9%] women; 1778 [90.1%] underwent abdominal operations). In the intention-to-treat analysis, the primary outcome occurred in 211 of 989 patients (21.3%) in the high level of PEEP group compared with 233 of 987 patients (23.6%) in the low level of PEEP group (difference, -2.3%[95% CI, -5.9% to 1.4%]; risk ratio, 0.93 [95% CI, 0.83 to 1.04]; P =.23). Among the 9 prespecified secondary outcomes, 6 were not significantly different between the high and low level of PEEP groups, and 3 were significantly different, including fewer patients with hypoxemia (5.0% in the high level of PEEP group vs 13.6% in the low level of PEEP group; difference, -8.6%[95% CI, -11.1% to 6.1%]; P <.001). CONCLUSIONS AND RELEVANCE Among obese patients undergoing surgery under general anesthesia, an intraoperative mechanical ventilation strategy with a higher level of PEEP and alveolar recruitment maneuvers, compared with a strategy with a lower level of PEEP, did not reduce postoperative pulmonary complications

Analysis of Shared Heritability in Common Disorders of the Brain

Disorders of the brain can exhibit considerable epidemiological comorbidity and often share symptoms, provoking debate about their etiologic overlap. We quantified the genetic sharing of 25 brain disorders from genome-wide association studies of 265,218 patients and 784,643 control participants and assessed their relationship to 17 phenotypes from 1,191,588 individuals. Psychiatric disorders share common variant risk, whereas neurological disorders appear more distinct from one another and from the psychiatric disorders. We also identified significant sharing between disorders and a number of brain phenotypes, including cognitive measures. Further, we conducted simulations to explore how statistical power, diagnostic misclassification, and phenotypic heterogeneity affect genetic correlations. These results highlight the importance of common genetic variation as a risk factor for brain disorders and the value of heritability-based methods in understanding their etiology