102 research outputs found

    The Strange Parton Distribution of the Nucleon: Global Analysis and Applications

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    The strangeness degrees of freedom in the parton structure of the nucleon are explored in the global analysis framework, using the new CTEQ6.5 implementation of the general mass perturbative QCD formalism of Collins. We systematically determine the constraining power of available hard scattering experimental data on the magnitude and shape of the strange quark and anti-quark parton distributions. We find that current data favor a distinct shape of the strange sea compared to the isoscalar non-strange sea. A new reference parton distribution set, CTEQ6.5S0, and representative sets spanning the allowed ranges of magnitude and shape of the strange distributions, are presented. Some applications to physical processes of current interest in hadron collider phenomenology are discussed.Comment: 19 pages; revised version submitted to JHE

    Merging Cellular Automata for Simulating Surface Effects

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    International audienceThis paper describes a model of three-dimensional cellular automata allowing to simulate diïŹ€erent phenomena in the ïŹelds of com- puter graphics and image processing, and to combine them together in order to produce complex eïŹ€ects such as automatic multitexturing, sur- face imperfections, or biological retina multi-layer cellular behaviours. Our cellular automaton model is deïŹned as a network of connected cells arranged in a natural and dynamic way, which aïŹ€ords multi-behavior ca- pabilities. Based on cheap and widespread computing systems, real-time performance can be reached for simulations involving up to a hundred thousand cells. Our approach eïŹƒciency is illustrated through a set of CA related to computer graphics –e.g. erosion, sedimentation, or vegetal growing processes– and image analysis –e.g. pipeline retina simulation

    SETD2 haploinsufficiency for microtubule methylation is an early driver of genomic instability in renal cell carcinoma

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    Loss of the short arm of chromosome 3 (3p) occurs early in >95% of clear cell renal cell carcinoma (ccRCC). Nearly ubiquitous 3p loss in ccRCC suggests haploinsufficiency for 3p tumor suppressors as early drivers of tumorigenesis. We previously reported methyltransferase SETD2, which trimethylates H3 histones on lysine 36 (H3K36me3) and is located in the 3p deletion, to also trimethylate microtubules on lysine 40 (aTubK40me3) during mitosis, with aTubK40me3 required for genomic stability. We now show that monoallelic, Setd2-deficient cells retaining H3K36me3, but not aTubK40me3, exhibit a dramatic increase in mitotic defects and micronuclei count, with increased viability compared with biallelic loss. In SETD2-inactivated human kidney cells, rescue with a pathogenic SETD2 mutant deficient for microtubule (aTubK40me3), but not histone (H3K36me3) methylation, replicated this phenotype. Genomic instability (micronuclei) was also a hallmark of patient-derived cells from ccRCC. These data show that the SETD2 tumor suppressor displays a haploinsufficiency phenotype disproportionately impacting microtubule methylation and serves as an early driver of genomic instability. Significance: Loss of a single allele of a chromatin modifier plays a role in promoting oncogenesis, underscoring the growing relevance of tumor suppressor haploinsufficiency in tumorigenesis

    Constraining Cut-off Physics in the Cosmic Microwave Background

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    We investigate the ability to constrain oscillatory features in the primordial power spectrum using current and future cosmic microwave background observations. In particular, we study the observability of an oscillation arising from imprints of physics at the cut-off energy scale. We perform a likelihood analysis on the WMAP data set, and find that the current data set constrains the amplitude of the oscillations to be less than 0.77 at 2-sigma, consistent with a power spectrum without oscillations. In addition, we investigate the fundamental limitations in the measurement of oscillation parameters by studying the constraints from a cosmic variance limited experiment. We find that such an experiment is capable of constraining the amplitude of such oscillations to be below 0.005, implying that reasonable models with cut-off energy scales Lambda>200 H_infl are unobservable through the microwave background.Comment: 16 pages, 7 figures; PRD accepted versio

    Measurement of the cross section for isolated-photon plus jet production in pp collisions at √s=13 TeV using the ATLAS detector

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    The dynamics of isolated-photon production in association with a jet in proton–proton collisions at a centre-of-mass energy of 13 TeV are studied with the ATLAS detector at the LHC using a dataset with an integrated luminosity of 3.2 fb−1. Photons are required to have transverse energies above 125 GeV. Jets are identified using the anti- algorithm with radius parameter and required to have transverse momenta above 100 GeV. Measurements of isolated-photon plus jet cross sections are presented as functions of the leading-photon transverse energy, the leading-jet transverse momentum, the azimuthal angular separation between the photon and the jet, the photon–jet invariant mass and the scattering angle in the photon–jet centre-of-mass system. Tree-level plus parton-shower predictions from Sherpa and Pythia as well as next-to-leading-order QCD predictions from Jetphox and Sherpa are compared to the measurements

    TRY plant trait database – enhanced coverage and open access

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    Plant traits—the morphological, anatomical, physiological, biochemical and phenological characteristics of plants—determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of trait‐based plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits—almost complete coverage for ‘plant growth form’. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and trait–environmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives

    A search for resonances decaying into a Higgs boson and a new particle X in the XH → qqbb final state with the ATLAS detector

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    A search for heavy resonances decaying into a Higgs boson (H) and a new particle (X) is reported, utilizing 36.1 fb−1 of proton–proton collision data at collected during 2015 and 2016 with the ATLAS detector at the CERN Large Hadron Collider. The particle X is assumed to decay to a pair of light quarks, and the fully hadronic final state is analysed. The search considers the regime of high XH resonance masses, where the X and H bosons are both highly Lorentz-boosted and are each reconstructed using a single jet with large radius parameter. A two-dimensional phase space of XH mass versus X mass is scanned for evidence of a signal, over a range of XH resonance mass values between 1 TeV and 4 TeV, and for X particles with masses from 50 GeV to 1000 GeV. All search results are consistent with the expectations for the background due to Standard Model processes, and 95% CL upper limits are set, as a function of XH and X masses, on the production cross-section of the resonance

    Comparison between simulated and observed LHC beam backgrounds in the ATLAS experiment at Ebeam =4 TeV

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    Results of dedicated Monte Carlo simulations of beam-induced background (BIB) in the ATLAS experiment at the Large Hadron Collider (LHC) are presented and compared with data recorded in 2012. During normal physics operation this background arises mainly from scattering of the 4 TeV protons on residual gas in the beam pipe. Methods of reconstructing the BIB signals in the ATLAS detector, developed and implemented in the simulation chain based on the \textscFluka Monte Carlo simulation package, are described. The interaction rates are determined from the residual gas pressure distribution in the LHC ring in order to set an absolute scale on the predicted rates of BIB so that they can be compared quantitatively with data. Through these comparisons the origins of the BIB leading to different observables in the ATLAS detectors are analysed. The level of agreement between simulation results and BIB measurements by ATLAS in 2012 demonstrates that a good understanding of the origin of BIB has been reached

    Search for an invisibly decaying Higgs boson or dark matter candidates produced in association with a Z boson in pp collisions at root s=13 TeV with the ATLAS detector

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