Overdentures on implants placed in bone augmented with fresh frozen bone

Introduction In the last decade several studies have been performed to evaluate the clinical outcome of one or two stage loaded implants supporting overdentures. Aim Since fresh frozen bone (FFB) has an ever-increasing number of clinical applications and few reports are available on implants inserted into FFB, we performed a retrospective study on fixtures inserted in FFB and bearing overdentures. Methods In the period between December 2003 and December 2006, 17 patients (14 females and 3 males with a median age of about 56 years) were grafted and 60 implants inserted thereafter. A total of 17 overdentures were delivered: 8 in the mandible and 9 in the maxilla. Multiple implant systems were used: 22 Double etched, 7 SLA, 9 Anodic oxidized, and 22 CaPo4 ceramic-blasted. Implant diameter ranged from 3.25 to 4.3 mm and length from 11.5 to 16.0 mm. Implants were inserted to replace 23 incisors, 9 cuspids, 20 premolars and 8 molars. Results No implants were lost (i.e. survival rate = 100%) and no differences were detected among the studied variables. Kaplan Meier algorithm and Cox regression did not reveal any statistical differences among the studied variables also as regards the success rate. Conclusion Implants inserted FFB and bearing overdentures have a high survival rate and success rates, which are comparable to those of implants inserted in non-grafted bone. FFB bone is a reliable material for alveolar ridge augmentation. No difference was detected among removable prostheses supported by 2 or more implants

Clinical outcome of narrow diameter implants inserted into allografts

OBJECTIVE: Narrow diameter implants (NDI) (i.e. diamete

Brushing the surface: cascade reactions between immobilized nanoreactors

Functionalization of hard or soft surfaces with, for example, ligands, enzymes or proteins, is an effective and practical methodology for the development of new applications. We report the assembly of two types of nanoreactors based upon poly(dimethylsiloxane)-block-poly(2-methyl-2-oxazoline) (PDMS-b-PMOXA) diblock copolymers as scaffold, uricase and lactoperoxidase as bio-catalysts located within the nanoreactors, and melittin as the biopores inserted into the hydrophobic shell. The nanoreactors were immobilized on poly(2-hydroxyethyl methacrylate)-co-poly(2-aminoethyl methacrylate hydrochloride) (PHEMA-co-P(2-AEMA·HCl) brushes-grafted wafer surfaces by utilizing the strong supramolecular interactions between biotin and streptavidin. The (PHEMA-co-P(2-AEMA·HCl) brushes on silicon surfaces were prepared by a surface initiating atom transfer radical polymerization (ATRP) "graft-from" technique. Cascade reactions between different surface-anchored nanoreactors were demonstrated by converting Amplex Red to the fluorescent probe resorufin by using the H2O2 produced from uric acid and H2O. The detailed properties of the nanoreactors on the functionalized surface including the binding behaviours and cascade reactions were investigated using emission spectroscopy, transmission electron microscopy (TEM), light scattering (LS), atomic force microscopy (AFM) and a quartz crystal microbalance (QCM-D). The results are proof-of-principle for the preparation of catalytically functional engineered surface materials and lay the foundation for applying this advanced functional surface material in biosensing, implanting and antimicrobial materials preparation

Wide Diameter Implants Inserted in Jaws Grafted with Homologue Bone

Svrha rada: Posljednjih deset godina povećala se uporaba implantata širokog promjera (WDI-a), posebice u lateralnim dijelovima čeljusti, uglavnom zbog dobrih kliničkih rezultata. No, malo je opisanih postupaka te objavljenih radova i ni jedan se ne bavi WDI-ma ugrađenima u transplantate homologne svježe zamrznute kosti (FFB-e). Zato smo obavili i retrospektivno istraživanje na nizu WDI-a postavljenih u homologne FFB-e, kako bismo ispitali kliničke rezultate. Materijal i metode: Ukupnom broju od 49 pacijenata ugrađeno je 126 WDI-a. Njih 35 imalo je dvostruko jetkanu površinu, 5 SLA1 površinu, 9 je bilo poprečno pjeskareno i jetkano kiselinom, 44 anodno oksidirano, 19 pjeskareno s CaPO4, 10 SLA2 površinu, a 4 su usatka imala neku drugu površinu. Rezultati: Samo jedan implantat bio je izgubljen (tj. SVR = 99,2%), a nije bilo razlike ni u ispitivanim varijablama. S druge strane, Coxova regresija pokazala je da su vrsta implantata (tj. dvostruko jetkana površina, površina pjeskarena CaPO4 i SLA2 površina) te njegova duæina (manja od 13 mm) u statistički znatnoj korelaciji s manjim gubitkom krestalne kosti, a time se omogućuje i bolji klinički ishod. Zaključak: Upotreba WDI-a u homolognom FFB-u može biti prihvatljiv način liječenja te može osigurati i neka poboljšanja, posebice u lateralnim dijelovima čeljusti za različita protetska rješenja poduprta usadcima.Objective of work: In the last decade the use of wide diameter implants (WDI) has increased especially in posterior jaws for their good clinical outcomes. However there are few reports on this topic and none on WDI inserted in homologue fresh frozen bone (FFB) grafts. Thus we planned a retrospective study on a series of WDI placed in homologuous FFB to evaluate the clinical outcome. Materials and Methods: 49 patients were operated on and 126 WDI inserted. There were 35 Double etched, 5 SLA1, 9 Grit blasted and acid etched, 44 Anodic Oxidized, 19 CaPo4 ceramic-blasted, 10 SLA2, and 4 miscellaneous implants. Results: Only 1 over in 126 WDI was lost (i.e. SVR = 99.2%) and no differences were detected among the studied variables. On the contrary, the Cox regression showed that implant type (i.e. Double etched, CaPo4 Ceramic-blasted, and SLA2) and implant length (i.e. length < 13 mm) correlated with a statistically signifi cant lower crestal bone loss and thus a better clinical outcome. Conclusion: The use of WDI inserted in homologuous FFB can be a viable treatment option and may provide benefi ts especially in posterior regions for the maintenance of various implant-supported prosthetic rehabilitations

Wide Diameter Implants Inserted in Jaws Grafted with Homologue Bone

Svrha rada: Posljednjih deset godina povećala se uporaba implantata širokog promjera (WDI-a), posebice u lateralnim dijelovima čeljusti, uglavnom zbog dobrih kliničkih rezultata. No, malo je opisanih postupaka te objavljenih radova i ni jedan se ne bavi WDI-ma ugrađenima u transplantate homologne svježe zamrznute kosti (FFB-e). Zato smo obavili i retrospektivno istraživanje na nizu WDI-a postavljenih u homologne FFB-e, kako bismo ispitali kliničke rezultate. Materijal i metode: Ukupnom broju od 49 pacijenata ugrađeno je 126 WDI-a. Njih 35 imalo je dvostruko jetkanu površinu, 5 SLA1 površinu, 9 je bilo poprečno pjeskareno i jetkano kiselinom, 44 anodno oksidirano, 19 pjeskareno s CaPO4, 10 SLA2 površinu, a 4 su usatka imala neku drugu površinu. Rezultati: Samo jedan implantat bio je izgubljen (tj. SVR = 99,2%), a nije bilo razlike ni u ispitivanim varijablama. S druge strane, Coxova regresija pokazala je da su vrsta implantata (tj. dvostruko jetkana površina, površina pjeskarena CaPO4 i SLA2 površina) te njegova duæina (manja od 13 mm) u statistički znatnoj korelaciji s manjim gubitkom krestalne kosti, a time se omogućuje i bolji klinički ishod. Zaključak: Upotreba WDI-a u homolognom FFB-u može biti prihvatljiv način liječenja te može osigurati i neka poboljšanja, posebice u lateralnim dijelovima čeljusti za različita protetska rješenja poduprta usadcima.Objective of work: In the last decade the use of wide diameter implants (WDI) has increased especially in posterior jaws for their good clinical outcomes. However there are few reports on this topic and none on WDI inserted in homologue fresh frozen bone (FFB) grafts. Thus we planned a retrospective study on a series of WDI placed in homologuous FFB to evaluate the clinical outcome. Materials and Methods: 49 patients were operated on and 126 WDI inserted. There were 35 Double etched, 5 SLA1, 9 Grit blasted and acid etched, 44 Anodic Oxidized, 19 CaPo4 ceramic-blasted, 10 SLA2, and 4 miscellaneous implants. Results: Only 1 over in 126 WDI was lost (i.e. SVR = 99.2%) and no differences were detected among the studied variables. On the contrary, the Cox regression showed that implant type (i.e. Double etched, CaPo4 Ceramic-blasted, and SLA2) and implant length (i.e. length < 13 mm) correlated with a statistically signifi cant lower crestal bone loss and thus a better clinical outcome. Conclusion: The use of WDI inserted in homologuous FFB can be a viable treatment option and may provide benefi ts especially in posterior regions for the maintenance of various implant-supported prosthetic rehabilitations