Isomeric and β-decay spectroscopy of 173,174Ho

β-decay spectroscopy of 173,174Ho (Z =67, N =106,107) was conducted at Radioactive Isotope Beam Factory at RIKEN by using in-flight fission of a 345-MeV/u 238U primary beam. A previously unreported isomeric state at 405 keV with half-life of 3.7(12) μs and a spin and parity of (3/2+) is identified in 173 Ho. Moreover, a new state with a spin and parity of 9− was discovered in 174 Er. The experimental log ft values of 5.84(20) and 5.25(18) suggest an allowed-hindered β decay from the ground state of 174Ho to the Kπ=8−isomeric state in 174Er. Configuration-constrained potential energy surface (PES) calculations were performed and the predictions are in reasonable agreement with the experimental results.Part of the WAS3ABi was supported by the Rare Isotopes Science Project which is funded by MSIP and NRF of Korea. This work was supported by JSPS KAKENHI Grants No. 24740188, No. 25247045, and No. 25287065, STFC (UK authors), the UK National Measurement Office (P.H.R.), the U.S. Department of Energy, Office of Science, Office of Nuclear Physics under Contract No. DE-AC02-06CH11357 (F.G.K.), NRF Korea Grants No. 2016R1D1A1A09917463, No. 2017M2A2A6A02071071 (C.S.L.), No. 2019R1F1A1058370, and No. 2016R1A5A1013277 (K.Y.C.), and Science Foundation Ireland under Grant No. 12/IP/1288 (O.J.R.)

Effect of allergens and irritants on levels of natural moisturizing factor and corneocyte morphology

BACKGROUND: The irritant sodium lauryl sulfate (SLS) is known to cause a decrease in the stratum corneum level of natural moisturizing factor (NMF), which in itself is associated with changes in corneocyte surface topography. ----- OBJECTIVE: To explore this phenomenon in allergic contact dermatitis. ----- METHODS: Patch testing was performed on patients with previously positive patch test reactions to potassium dichromate (Cr), nickel sulfate (Ni), methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI), or p-phenylenediamine. Moreover, a control (pet.) patch and an irritant (SLS) patch were applied. After 3 days, the stratum corneum from tested sites was collected, and NMF levels and corneocyte morphology, expressed as the amount of circular nanosize objects, quantified according to the Dermal Texture Index (DTI), were determined. ----- RESULTS: Among allergens, only MCI/MI reduced NMF levels significantly, as did SLS. Furthermore, only MCI/MI caused remarkable changes at the microscopic level; the corneocytes were hexagonal-shaped with pronounced cell borders and a smoother surface. The DTI was increased after SLS exposure but not after allergen exposure. ----- CONCLUSIONS: MCI/MI significantly decreased NMF levels, similarly to SLS. The altered corneocyte morphology suggests that skin barrier damage plays a role in the pathogenesis of MCI/MI contact allergy. The DTI seems to differentiate reactions to SLS from those to the allergens tested, as SLS was the only agent that caused a DTI increase

Search for leptophobic Z ' bosons decaying into four-lepton final states in proton-proton collisions at root s=8 TeV

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Search for black holes and other new phenomena in high-multiplicity final states in proton-proton collisions at root s=13 TeV

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Measurements of differential production cross sections for a Z boson in association with jets in pp collisions at root s=8 TeV

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Search for high-mass diphoton resonances in proton-proton collisions at 13 TeV and combination with 8 TeV search

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