Rastreamento oportunístico do câncer de mama desenvolvido por enfermeiros da Atenção Primária à Saúde

OBJETIVO Identificar las acciones de rastreo oportunista del cáncer de mama llevadas a cabo por enfermeros de unidades básicas de salud (UBS) de Ribeirão Preto. MÉTODO Estudio transversal, con 60 enfermeros de 28 Unidades, actuantes desde hace un año en la red municipal de salud. Los datos fueron recogidos entre diciembre de 2013 y marzo de 2014, mediante formulario, analizado descriptivamente empleándose los softwares IBM SPSS 20 y Excel 2010. RESULTADOS Señalaron que el 71,7% realizaron investigación acerca de los factores de riesgo del cáncer de mama, especialmente durante la consulta de enfermería; el 70,0% orientan a la mujer con respecto a la edad para realizar el Examen Clínico de las Mamas; el 30,0% de ellos no lo realizan por falta de conocimiento y tiempo; el 60,0% explican sobre la edad para la realización de la mamografía; el 73,3% no derivan a las usuarias con resultado sospechoso a la unidad de referencia, alegando la programación como principal obstáculo para su ejecución. Las actividades educativas no las llevan a cabo el 78,3% de los profesionales. CONCLUSIÓN Existe necesidad de inversiones en capacitación profesional y gestión de los servicios sanitarios.OBJECTIVE To identify opportunistic screening actions for breast cancer performed by nurses working in primary health care units in Ribeirão Preto, São Paulo. METHOD Cross-sectional study with 60 nurses from 28 units, who had been working for at least one year in the public municipal health care network. Data were collected between December 2013 and March 2014, by means of a questionnaire, using descriptive analysis and the software IBM SPSS version 20 and Microsoft Excel 2010. RESULTS The results showed that 71.7% of the participants questioned their female patients as for risk factors for breast cancer, mainly during nursing consultation; 70.0% oriented users about the age to perform clinical breast exam, whereas 30.0% did not due to lack of knowledge and time; 60.0% explained about the age to perform mammogram; 73.3% did not refer patients with suspicious breast exam results to the referral department, citing scheduling as the main obstacle to referral. Educational activities were not performed by 78.3% of participants. CONCLUSION Investment is needed in professional training and management of breast cancer screening.OBJETIVO Identificar as ações de rastreamento oportunístico do câncer de mama realizadas por enfermeiros de unidades básicas de saúde (UBS) de Ribeirão Preto. MÉTODO Estudo transversal, com 60 enfermeiros de 28 Unidades, atuantes há um ano na rede municipal de saúde. Os dados foram coletados entre dezembro de 2013 e março de 2014, por meio de formulário, analisado descritivamente, utilizando os softwares IBM SPSS 20 e Excel 2010. RESULTADOS Apontaram que 71,7% realizam investigação sobre os fatores de risco do câncer de mama, principalmente durante a consulta de enfermagem; 70,0% orientam a mulher acerca da idade para realizar Exame Clínico das Mamas; 30,0% deles não o realizam por falta de conhecimento e tempo; 60,0% explicam sobre a idade para realização da mamografia; 73,3% não encaminham as usuárias com resultado suspeito à unidade de referência, alegando o agendamento como principal entrave para sua execução. As atividades educativas não são realizadas por 78,3% dos profissionais. CONCLUSÃO Há necessidade de investimentos em capacitação profissional e gerenciamento dos serviços de saúde

Opportunistic screening actions for breast cancer performed by nurses working in primary health care

Objective: To identify opportunistic screening actions for breast cancer performed by nurses working in primary health care units in Ribeirao Preto, Sao Paulo. Method: Cross-sectional study with 60 nurses from 28 units, who had been working for at least one year in the public municipal health care network. Data were collected between December 2013 and March 2014, by means of a questionnaire, using descriptive analysis and the software IBM SPSS version 20 and Microsoft Excel 2010. Results: The results showed that 71.7% of the participants questioned their female patients as for risk factors for breast cancer, mainly during nursing consultation; 70.0% oriented users about the age to perform clinical breast exam, whereas 30.0% did not due to lack of knowledge and time; 60.0% explained about the age to perform mammogram; 73.3% did not refer patients with suspicious breast exam results to the referral department, citing scheduling as the main obstacle to referral. Educational activities were not performed by 78.3% of participants. Conclusion: Investment is needed in professional training and management of breast cancer screening.Univ Sao Paulo, Escola Enfermagem Ribeirao Preto, Programa Posgrad Enfermagem Saude Publ, BR-14049 Ribeirao Preto, SP, BrazilUniv Sao Paulo, Escola Enfermagem Ribeirao Preto, Dept Enfermagem Geral & Especializada, BR-14049 Ribeirao Preto, SP, BrazilUniv Fed Sao Paulo, Escola Paulista Enfermagem, Sao Paulo, SP, BrazilUniv Jose do Rosario Vellano, Alfenas, MG, BrazilUniv Sao Paulo, Escola Enfermagem Ribeirao Preto, Dept Enfermagem Materno Infantil & Saude Publ, Ribeirao Preto, SP, BrazilUniv Fed Sao Paulo, Escola Paulista Enfermagem, Sao Paulo, SP, BrazilWeb of Scienc

Developmental regulation of N-terminal H2B methylation in Drosophila melanogaster

Histone post-translational modifications play an important role in regulating chromatin structure and gene expression in vivo. Extensive studies investigated the post-translational modifications of the core histones H3 and H4 or the linker histone H1. Much less is known on the regulation of H2A and H2B modifications. Here, we show that a major modification of H2B in Drosophila melanogaster is the methylation of the N-terminal proline, which increases during fly development. Experiments performed in cultured cells revealed higher levels of H2B methylation when cells are dense, regardless of their cell cycle distribution. We identified dNTMT (CG1675) as the enzyme responsible for H2B methylation. We also found that the level of N-terminal methylation is regulated by dART8, an arginine methyltransferase that physically interacts with dNTMT and asymmetrically methylates H3R2. Our results demonstrate the existence of a complex containing two methyltransferases enzymes, which negatively influence each other’s activity

Emissions of sulphur dioxide (SO2) from coal-fired power plants in Serbia and Bosnia-Herzegovina: First attempts of a validation of TROPOMI satellite products with airborne in situ measurements

The Western Balkan region is known for emitting alarmingly high sulphur dioxide amounts from coal-fired power plants. Though a number of environmental regulations have been introduced in recent years (e.g. desulphurisation installations, construction of modern power plants), the pollution burden is still much higher than recommended by the authorities. A number of different montoring systems are required to observe the growing pollution situation in the Western Balkan region, partly caused by a high energy demand from outside (e.g. Western Europe)

Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements