297 research outputs found
Superradiation from Crystals of High-Spin Molecular Nanomagnets
Phenomenological theory of superradiation from crystals of high-spin
molecules is suggested. We show that radiation friction can cause a
superradiation pulse and investigate the role of magnetic anisotropy, external
magnetic field and dipole-dipole interactions. Depending on the contribution of
all these factors at low temperature, several regimes of magnetization of
crystal sample are described. Very fast switch of magnetization's direction for
some sets of parameters is predicted.Comment: 10 pages, 3 figure
Homogeneous Modes of Cosmological Instantons
We discuss the O(4) invariant perturbation modes of cosmological instantons.
These modes are spatially homogeneous in Lorentzian spacetime and thus not
relevant to density perturbations. But their properties are important in
establishing the meaning of the Euclidean path integral. If negative modes are
present, the Euclidean path integral is not well defined, but may nevertheless
be useful in an approximate description of the decay of an unstable state. When
gravitational dynamics is included, counting negative modes requires a careful
treatment of the conformal factor problem. We demonstrate that for an
appropriate choice of coordinate on phase space, the second order Euclidean
action is bounded below for normalized perturbations and has a finite number of
negative modes. We prove that there is a negative mode for many gravitational
instantons of the Hawking-Moss or Coleman-De Luccia type, and discuss the
associated spectral flow. We also investigate Hawking-Turok constrained
instantons, which occur in a generic inflationary model. Implementing the
regularization and constraint proposed by Kirklin, Turok and Wiseman, we find
that those instantons leading to substantial inflation do not possess negative
modes. Using an alternate regularization and constraint motivated by reduction
from five dimensions, we find a negative mode is present. These investigations
shed new light on the suitability of Euclidean quantum gravity as a potential
description of our universe.Comment: 16 pages, compressed and RevTex file, including one postscript figure
fil
Low-Energy Universality in Atomic and Nuclear Physics
An effective field theory developed for systems interacting through
short-range interactions can be applied to systems of cold atoms with a large
scattering length and to nucleons at low energies. It is therefore the ideal
tool to analyze the universal properties associated with the Efimov effect in
three- and four-body systems. In this "progress report", we will discuss recent
results obtained within this framework and report on progress regarding the
inclusion of higher order corrections associated with the finite range of the
underlying interaction.Comment: Commissioned article for Few-Body Systems, 47 pp, 16 fig
Linear stability analysis of retrieval state in associative memory neural networks of spiking neurons
We study associative memory neural networks of the Hodgkin-Huxley type of
spiking neurons in which multiple periodic spatio-temporal patterns of spike
timing are memorized as limit-cycle-type attractors. In encoding the
spatio-temporal patterns, we assume the spike-timing-dependent synaptic
plasticity with the asymmetric time window. Analysis for periodic solution of
retrieval state reveals that if the area of the negative part of the time
window is equivalent to the positive part, then crosstalk among encoded
patterns vanishes. Phase transition due to the loss of the stability of
periodic solution is observed when we assume fast alpha-function for direct
interaction among neurons. In order to evaluate the critical point of this
phase transition, we employ Floquet theory in which the stability problem of
the infinite number of spiking neurons interacting with alpha-function is
reduced into the eigenvalue problem with the finite size of matrix. Numerical
integration of the single-body dynamics yields the explicit value of the
matrix, which enables us to determine the critical point of the phase
transition with a high degree of precision.Comment: Accepted for publication in Phys. Rev.
The New Urban Revival in the United States
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68657/2/10.1080_00420989320081901.pd
Search for direct production of charginos and neutralinos in events with three leptons and missing transverse momentum in âs = 7 TeV pp collisions with the ATLAS detector
A search for the direct production of charginos and neutralinos in final states with three electrons or muons and missing transverse momentum is presented. The analysis is based on 4.7 fbâ1 of protonâproton collision data delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in three signal regions that are either depleted or enriched in Z-boson decays. Upper limits at 95% confidence level are set in R-parity conserving phenomenological minimal supersymmetric models and in simplified models, significantly extending previous results
Jet size dependence of single jet suppression in lead-lead collisions at sqrt(s(NN)) = 2.76 TeV with the ATLAS detector at the LHC
Measurements of inclusive jet suppression in heavy ion collisions at the LHC
provide direct sensitivity to the physics of jet quenching. In a sample of
lead-lead collisions at sqrt(s) = 2.76 TeV corresponding to an integrated
luminosity of approximately 7 inverse microbarns, ATLAS has measured jets with
a calorimeter over the pseudorapidity interval |eta| < 2.1 and over the
transverse momentum range 38 < pT < 210 GeV. Jets were reconstructed using the
anti-kt algorithm with values for the distance parameter that determines the
nominal jet radius of R = 0.2, 0.3, 0.4 and 0.5. The centrality dependence of
the jet yield is characterized by the jet "central-to-peripheral ratio," Rcp.
Jet production is found to be suppressed by approximately a factor of two in
the 10% most central collisions relative to peripheral collisions. Rcp varies
smoothly with centrality as characterized by the number of participating
nucleons. The observed suppression is only weakly dependent on jet radius and
transverse momentum. These results provide the first direct measurement of
inclusive jet suppression in heavy ion collisions and complement previous
measurements of dijet transverse energy imbalance at the LHC.Comment: 15 pages plus author list (30 pages total), 8 figures, 2 tables,
submitted to Physics Letters B. All figures including auxiliary figures are
available at
http://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/HION-2011-02
Evolutionary origins of the estrogen signaling system : insights from amphioxus
Author Posting. © The Author(s), 2011. This is the author's version of the work. It is posted here by permission of Elsevier B.V. for personal use, not for redistribution. The definitive version was published in Journal of Steroid Biochemistry and Molecular Biology 127 (2011): 176â188, doi:10.1016/j.jsbmb.2011.03.022.Classically, the estrogen signaling system has two core components: cytochrome P450
aromatase (CYP19), the enzyme complex that catalyzes the rate limiting step in estrogen
biosynthesis; and estrogen receptors (ERs), ligand activated transcription factors that interact
with the regulatory region of target genes to mediate the biological effects of estrogen. While the
importance of estrogens for regulation of reproduction, development and physiology has been
well-documented in gnathostome vertebrates, the evolutionary origins of estrogen as a hormone
are still unclear. As invertebrates within the phylum Chordata, cephalochordates (e.g. the
amphioxus of the genus Branchiostoma) are among the closest invertebrate relatives of the
vertebrates and can provide critical insight into the evolution of vertebrate-specific molecules
and pathways. To address this question, this paper briefly reviews relevant earlier studies that
help to illuminate the history of the aromatase and ER genes, with a particular emphasis on
insights from amphioxus and other invertebrates. We then present new analyses of amphioxus
aromatase and ER sequence and function, including an in silico model of the amphioxus
aromatase protein, and CYP19 gene analysis. CYP19 shares a conserved gene structure with
vertebrates (9 coding exons) and moderate sequence conservation (40% amino acid identity with
human CYP19). Modeling of the amphioxus aromatase substrate binding site and simulated
docking of androstenedione in comparison to the human aromatase shows that the substrate
binding site is conserved and predicts that androstenedione could be a substrate for amphioxus
CYP19. The amphioxus ER is structurally similar to vertebrate ERs, but differs in sequence and
key residues of the ligand binding domain. Consistent with results from other laboratories,
amphioxus ER did not bind radiolabeled estradiol, nor did it modulate gene expression on an estrogen-responsive element (ERE) in the presence 59 of estradiol, 4-hydroxytamoxifen,
diethylstilbestrol, bisphenol A or genistein. Interestingly, it has been shown that a related gene,
the amphioxus âsteroid receptorâ (SR), can be activated by estrogens and that amphioxus ER can
repress this activation. CYP19, ER and SR are all primarily expressed in gonadal tissue,
suggesting an ancient paracrine/autocrinesignaling role, but it is not yet known how their
expression is regulated and, if estrogen is actually synthesized in amphioxus, whether it has a
role in mediating any biological effects . Functional studies are clearly needed to link emerging
bioinformatics and in vitro molecular biology results with organismal physiology to develop an
understanding of the evolution of estrogen signaling.Supported by grants from the NIEHS P42 ES07381 (GVC, SV) and EPA (STAR-RD831301)
(GVC), a Ruth L Kirschstein National Research Service Award (AT, F32 ES013092-01), an NIH
traineeship (SS, SG), a NATO Fellowship (AN) and the Boston University Undergraduate
Research Program (LC)
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