293 research outputs found
Responses of Helicoverpa armigera to tomato plants previously infected by ToMV or damaged by H-Armigera
We report the comparative inducing effects of a phytopathogen and a herbivorous arthropod on the performance of an herbivore. Tomato, Lycopersicon esculentum Mill., was used as the test plant, and tomato mosaic virus (ToMV) and corn earworm, Helicoverpa armigera Hubner, were used as the phytopathogen and herbivore, respectively. There were decreases in the efficiency of conversion of ingested food and efficiency of conversion of digested food when H. armigera was reared on tomato plants that had been previously inoculated with ToMV. However, virus inoculation did not affect feeding or oviposition preferences by H. armigera. In contrast, approximate digestibility, total consumption, relative growth rate, and relative consumption rate were lower for fourth-instar H. armigera that fed on plants previously damaged by the same herbivore. Feeding and oviposition were both deterred for H. armigera that fed on previously damaged plants. The duration of development of H. armigera was also prolonged under this treatment. Infection by ToMV and feeding damage by H. armigera increased the host plant's peroxidase and polyphenol oxidase activity, respectively, suggesting that the performance of H. armigera may be affected by the induced phytochemistry of the host plant. Overall, this study indicated that, in general, insect damage has a stronger effect than ToMV infection on plant chemistry and, subsequently, on the performance of H. armigera
Gamma-ray emission expected from Kepler's SNR
Nonlinear kinetic theory of cosmic ray (CR) acceleration in supernova
remnants (SNRs) is used to investigate the properties of Kepler's SNR and, in
particular, to predict the gamma-ray spectrum expected from this SNR.
Observations of the nonthermal radio and X-ray emission spectra as well as
theoretical constraints for the total supernova (SN) explosion energy E_sn are
used to constrain the astronomical and particle acceleration parameters of the
system. Under the assumption that Kepler's SN is a type Ia SN we determine for
any given explosion energy E_sn and source distance d the mass density of the
ambient interstellar medium (ISM) from a fit to the observed SNR size and
expansion speed. This makes it possible to make predictions for the expected
gamma-ray flux. Exploring the expected distance range we find that for a
typical explosion energy E_sn=10^51 erg the expected energy flux of TeV
gamma-rays varies from 2x10^{-11} to 10^{-13} erg/(cm^2 s) when the distance
changes from d=3.4 kpc to 7 kpc. In all cases the gamma-ray emission is
dominated by \pi^0-decay gamma-rays due to nuclear CRs. Therefore Kepler's SNR
represents a very promising target for instruments like H.E.S.S., CANGAROO and
GLAST. A non-detection of gamma-rays would mean that the actual source distance
is larger than 7 kpc.Comment: 6 pages, 4 figures. Accepted for publication in Astronomy and
Astrophysics, minor typos correcte
Giant Shapiro steps for two-dimensional Josephson-junction arrays with time-dependent Ginzburg-Landau dynamics
Two-dimensional Josephson junction arrays at zero temperature are
investigated numerically within the resistively shunted junction (RSJ) model
and the time-dependent Ginzburg-Landau (TDGL) model with global conservation of
current implemented through the fluctuating twist boundary condition (FTBC).
Fractional giant Shapiro steps are found for {\em both} the RSJ and TDGL cases.
This implies that the local current conservation, on which the RSJ model is
based, can be relaxed to the TDGL dynamics with only global current
conservation, without changing the sequence of Shapiro steps. However, when the
maximum widths of the steps are compared for the two models some qualitative
differences are found at higher frequencies. The critical current is also
calculated and comparisons with earlier results are made. It is found that the
FTBC is a more adequate boundary condition than the conventional uniform
current injection method because it minimizes the influence of the boundary.Comment: 6 pages including 4 figures in two columns, final versio
Dynamics of multipartite quantum correlations under decoherence
Quantum discord is an optimal resource for the quantification of classical
and non-classical correlations as compared to other related measures. Geometric
measure of quantum discord is another measure of quantum correlations.
Recently, the geometric quantum discord for multipartite states has been
introduced by Jianwei Xu [arxiv:quant/ph.1205.0330]. Motivated from the recent
study [Ann. Phys. 327 (2012) 851] for the bipartite systems, I have
investigated global quantum discord (QD) and geometric quantum discord (GQD)
under the influence of external environments for different multipartite states.
Werner-GHZ type three-qubit and six-qubit states are considered in inertial and
non-inertial settings. The dynamics of QD and GQD is investigated under
amplitude damping, phase damping, depolarizing and flipping channels. It is
seen that the quantum discord vanishes for p>0.75 in case of three-qubit GHZ
states and for p>0.5 for six qubit GHZ states. This implies that multipartite
states are more fragile to decoherence for higher values of N. Surprisingly, a
rapid sudden death of discord occurs in case of phase flip channel. However,
for bit flip channel, no sudden death happens for the six-qubit states. On the
other hand, depolarizing channel heavily influences the QD and GQD as compared
to the amplitude damping channel. It means that the depolarizing channel has
the most destructive influence on the discords for multipartite states. From
the perspective of accelerated observers, it is seen that effect of environment
on QD and GQD is much stronger than that of the acceleration of non-inertial
frames. The degradation of QD and GQD happens due to Unruh effect. Furthermore,
QD exhibits more robustness than GQD when the multipartite systems are exposed
to environment.Comment: 15 pages, 4 figures, 4 table
Anisotropic flow of charged hadrons, pions and (anti-)protons measured at high transverse momentum in Pb-Pb collisions at TeV
The elliptic, , triangular, , and quadrangular, , azimuthal
anisotropic flow coefficients are measured for unidentified charged particles,
pions and (anti-)protons in Pb-Pb collisions at TeV
with the ALICE detector at the Large Hadron Collider. Results obtained with the
event plane and four-particle cumulant methods are reported for the
pseudo-rapidity range at different collision centralities and as a
function of transverse momentum, , out to GeV/.
The observed non-zero elliptic and triangular flow depends only weakly on
transverse momentum for GeV/. The small dependence
of the difference between elliptic flow results obtained from the event plane
and four-particle cumulant methods suggests a common origin of flow
fluctuations up to GeV/. The magnitude of the (anti-)proton
elliptic and triangular flow is larger than that of pions out to at least
GeV/ indicating that the particle type dependence persists out
to high .Comment: 16 pages, 5 captioned figures, authors from page 11, published
version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/186
Centrality dependence of charged particle production at large transverse momentum in Pb-Pb collisions at TeV
The inclusive transverse momentum () distributions of primary
charged particles are measured in the pseudo-rapidity range as a
function of event centrality in Pb-Pb collisions at
TeV with ALICE at the LHC. The data are presented in the range
GeV/ for nine centrality intervals from 70-80% to 0-5%.
The Pb-Pb spectra are presented in terms of the nuclear modification factor
using a pp reference spectrum measured at the same collision
energy. We observe that the suppression of high- particles strongly
depends on event centrality. In central collisions (0-5%) the yield is most
suppressed with at -7 GeV/. Above
GeV/, there is a significant rise in the nuclear modification
factor, which reaches for GeV/. In
peripheral collisions (70-80%), the suppression is weaker with almost independently of . The measured nuclear
modification factors are compared to other measurements and model calculations.Comment: 17 pages, 4 captioned figures, 2 tables, authors from page 12,
published version, figures at
http://aliceinfo.cern.ch/ArtSubmission/node/284
Measurement of charm production at central rapidity in proton-proton collisions at TeV
The -differential production cross sections of the prompt (B
feed-down subtracted) charmed mesons D, D, and D in the rapidity
range , and for transverse momentum GeV/, were
measured in proton-proton collisions at TeV with the ALICE
detector at the Large Hadron Collider. The analysis exploited the hadronic
decays DK, DK, DD, and their charge conjugates, and was performed on a
nb event sample collected in 2011 with a
minimum-bias trigger. The total charm production cross section at TeV and at 7 TeV was evaluated by extrapolating to the full phase space
the -differential production cross sections at TeV
and our previous measurements at TeV. The results were compared
to existing measurements and to perturbative-QCD calculations. The fraction of
cdbar D mesons produced in a vector state was also determined.Comment: 20 pages, 5 captioned figures, 4 tables, authors from page 15,
published version, figures at
http://aliceinfo.cern.ch/ArtSubmission/node/307
Particle-yield modification in jet-like azimuthal di-hadron correlations in Pb-Pb collisions at = 2.76 TeV
The yield of charged particles associated with high- trigger
particles ( GeV/) is measured with the ALICE detector in
Pb-Pb collisions at = 2.76 TeV relative to proton-proton
collisions at the same energy. The conditional per-trigger yields are extracted
from the narrow jet-like correlation peaks in azimuthal di-hadron correlations.
In the 5% most central collisions, we observe that the yield of associated
charged particles with transverse momenta GeV/ on the
away-side drops to about 60% of that observed in pp collisions, while on the
near-side a moderate enhancement of 20-30% is found.Comment: 15 pages, 2 captioned figures, 1 table, authors from page 10,
published version, figures at
http://aliceinfo.cern.ch/ArtSubmission/node/350
Efficacy of the herpes zoster subunit vaccine in adults 70 years of age or older
Background: A trial involving adults 50 years of age or older (ZOE-50) showed that the herpes zoster subunit vaccine (HZ/su) containing recombinant varicella-zoster virus glycoprotein E and the AS01B adjuvant system was associated with a risk of herpes zoster that was 97.2% lower than that associated with placebo. A second trial was performed concurrently at the same sites and examined the safety and efficacy of HZ/su in adults 70 years of age or older (ZOE-70). Methods: This randomized, placebo-controlled, phase 3 trial was conducted in 18 countries and involved adults 70 years of age or older. Participants received two doses of HZ/su or placebo (assigned in a 1:1 ratio) administered intramuscularly 2 months apart. Vaccine efficacy against herpes zoster and postherpetic neuralgia was assessed in participants from ZOE-70 and in participants pooled from ZOE-70 and ZOE-50. Results: In ZOE-70, 13,900 participants who could be evaluated (mean age, 75.6 years) received either HZ/su (6950 participants) or placebo (6950 participants). During a mean follow-up period of 3.7 years, herpes zoster occurred in 23 HZ/su recipients and in 223 placebo recipients (0.9 vs. 9.2 per 1000 person-years). Vaccine efficacy against herpes zoster was 89.8% (95% confidence interval [CI], 84.2 to 93.7; P<0.001) and was similar in participants 70 to 79 years of age (90.0%) and participants 80 years of age or older (89.1%). In pooled analyses of data from participants 70 years of age or older in ZOE-50 and ZOE-70 (16,596 participants), vaccine efficacy against herpes zoster was 91.3% (95% CI, 86.8 to 94.5; P<0.001), and vaccine efficacy against postherpetic neuralgia was 88.8% (95% CI, 68.7 to 97.1; P<0.001). Solicited reports of injection-site and systemic reactions within 7 days after injection were more frequent among HZ/su recipients than among placebo recipients (79.0% vs. 29.5%). Serious adverse events, potential immune-mediated diseases, and deaths occurred with similar frequencies in the two study groups. Conclusions: In our trial, HZ/su was found to reduce the risks of herpes zoster and postherpetic neuralgia among adults 70 years of age or older. <br /
Fine-Scale Mapping of the 4q24 Locus Identifies Two Independent Loci Associated with Breast Cancer Risk
Background: A recent association study identified a common variant (rs9790517) at 4q24 to be associated with breast cancer risk. Independent association signals and potential functional variants in this locus have not been explored.
Methods: We conducted a fine-mapping analysis in 55,540 breast cancer cases and 51,168 controls from the Breast Cancer Association Consortium.
Results: Conditional analyses identified two independent association signals among women of European ancestry, represented by rs9790517 [conditional P = 2.51 × 10−4; OR, 1.04; 95% confidence interval (CI), 1.02–1.07] and rs77928427 (P = 1.86 × 10−4; OR, 1.04; 95% CI, 1.02–1.07). Functional annotation using data from the Encyclopedia of DNA Elements (ENCODE) project revealed two putative functional variants, rs62331150 and rs73838678 in linkage disequilibrium (LD) with rs9790517 (r2 ≥ 0.90) residing in the active promoter or enhancer, respectively, of the nearest gene, TET2. Both variants are located in DNase I hypersensitivity and transcription factor–binding sites. Using data from both The Cancer Genome Atlas (TCGA) and Molecular Taxonomy of Breast Cancer International Consortium (METABRIC), we showed that rs62331150 was associated with level of expression of TET2 in breast normal and tumor tissue.
Conclusion: Our study identified two independent association signals at 4q24 in relation to breast cancer risk and suggested that observed association in this locus may be mediated through the regulation of TET2.
Impact: Fine-mapping study with large sample size warranted for identification of independent loci for breast cancer risk
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