136 research outputs found
Amanda
- Author
- Publication venue
- Publication date
- 27/07/2017
- Field of study
"Amanda" is a stop-motion animated short film, shot in stereoscopic 3D. Using fairy tale themes, it tells the story of a young girl who is struggling to control her emotions. Lost in a dark swamp, she encounters a troll who catches and consumes her. She must eventually outwit him in order to return home
Constraining a Model of the Radio Sky Below 6 MHz Using the Parker Solar Probe/FIELDS Instrument in Preparation for Upcoming Lunar-based Experiments
- Publication venue
- Publication date
- 01/01/2023
- Field of study
We present a Bayesian analysis of data from the FIELDS instrument on board
the Parker Solar Probe (PSP) spacecraft with the aim of constraining low
frequency (âČ 6 MHz) sky in preparation for several upcoming
lunar-based experiments. We utilize data recorded during PSP's ``coning roll''
maneuvers, in which the axis of the spacecraft is pointed 45â off of
the Sun. The spacecraft then rotates about a line between the Sun and the
spacecraft with a period of 24 minutes. We reduce the data into two formats:
roll-averaged, in which the spectra are averaged over the roll, and
phase-binned, in which the spectra are binned according to the phase of the
roll. We construct a forward model of the FIELDS observations that includes
numerical simulations of the antenna beam, an analytic emissivity function of
the galaxy, and estimates of the absorption due to free electrons. Fitting 5
parameters, we find that the roll-averaged data can be fit well by this model
and we obtain posterior parameter constraints that are in general agreement
with previous estimates. The model is not, however, able to fit the
phase-binned data well, likely due to limitations such as the lack of
non-smooth emission structure at both small and large scales, enforced symmetry
between the northern and southern galactic hemispheres, and large uncertainties
in the free electron density. This suggests that significant improvement in the
low frequency sky model is needed in order to fully and accurately represent
the sky at frequencies below 6 MHz.Comment: 18 pages, 10 figures, 5 tables. Under review in the Astrophysical
Journa
Assessment of abdominal aortic aneurysm biology using magnetic resonance imaging and positron emission tomography-computed tomography.
- Author
- Berry Colin
- Brittenden Julie
- Bucukoglu Marise
- Burns Paul
- Chalmers Roderick
- Conlisk Noel
- Cooper Annette
- Cuthbert Hayley
- Doyle Barry
- Dweck Marc
- Forsythe Rachael
- Fraser Liz
- Garden O James
- Goodman Kirsteen
- Graham Catriona
- Gray Calum
- Ho Weiyang
- Holdsworth Richard
- Hoskins Peter
- Kaczynski Jakub
- Koutraki Yolanda Georgia
- Lambie Robert
- MacGillivray Tom
- McBride Olivia
- McKillop Graham
- Milne Garry
- Milne Lyndsey
- Mitchard Neil
- Murdoch Laura
- Murray Gordon
- Newby David
- Norrie John
- Oatey Katerine
- Robson Jennifer
- Roditi Giles
- Scott Emma
- Semple Scott
- Shah Anoop S V
- Strachan Fiona
- Stuart Wesley
- Tambyraja Andrew
- van Beek Edwin
- Vesey Alex
- Wang Chengjia
- Wee Fiona
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 01/08/2017
- Field of study
Background
Although abdominal aortic aneurysm (AAA) growth is non-linear, serial
measurements of aneurysm diameter are the mainstay of aneurysm surveillance and
contribute to decisions on timing of intervention. Aneurysm biology plays a key part
in disease evolution but is not currently routinely assessed in clinical practice.
Magnetic Resonance Imaging (MRI) and Positron Emission Tomography-Computed
Tomography (PET-CT) provide insight into disease processes on a cellular or
molecular level, and represent exciting new imaging biomarkers of disease activity.
Macrophage-mediated inflammation may be assessed using ultrasmall
superparamagnetic particles of iron oxide (USPIO) MRI and the PET radiotracer 18FSodium
Fluoride (18F-NaF) identifies microcalcification which is a response to
underlying necrotic inflammation. The central aim of this thesis was to investigate
these imaging modalities in patients with AAA.
Methods and Results
USPIO MRI: MULTI-CENTRE STUDY
In a prospective multi-centre observational cohort study, 342 patients (85.4% male,
mean age 73.1±7.2 years, mean AAA diameter 49.6±7.7mm) with asymptomatic
AAA â„4 cm anteroposterior diameter underwent MRI before and 24-36 hours after
intravenous administration of USPIO. Colour maps (depicting the change in T2*
caused by USPIO) were used to classify aneurysms on the basis of the presence of
USPIO uptake in the aneurysm wall, representing mural inflammation. Intra- and
inter-observer agreement were found to be very good, with proportional agreement
of 0.91 (kappa 0.82) and 0.83 (kappa 0.66), respectively. At 1 year, there was 29.3%
discordant classification of aneurysms on repeated USPIO MRI and at 2 years,
discordance was 65%, suggesting that inflammation evolves over time. In the
observational study, after a mean of 1005±280 days of follow up, there were 126
(36.8%) aneurysm repairs and 17 (5.0%) ruptures. Participants with USPIO
enhancement (42.7%) had increased aneurysm expansion rates (3·1±2·5 versus
2·5±2·4 mm/year; difference 0·6 [95% confidence intervals (CI), 0·02 to 1·2]
mm/year, p=0·0424) and had higher rates of aneurysm rupture or repair
(69/146=47·3% versus 68/191=35·6%; difference 11·7%, 95% CI 1·1 to 22·2%,
p=0·0308). USPIO MRI was therefore shown to predict AAA expansion and the
composite of rupture or repair, however this was not independent of aneurysm
diameter (c-statistic, 0·7924 to 0·7926; unconditional net reclassification -13·5%,
95% confidence intervals -36·4% to 9·3%).
18F-NaF PET-CT: SINGLE-CENTRE STUDY
A sub-group of 76 patients also underwent 18F-NaF PET-CT, which was evaluated
using the maximum tissue-to-background ratio (TBRmax) in the most diseased
segment (MDS), a technique that showed very good intra- (ICC 0.70-0.89) and inter-observer
(ICC 0.637-0.856) agreement. Aneurysm tracer uptake was compared
firstly in a case-control study, with 20 patients matched to 20 control patients for age,
sex and smoking status. 18F-NaF uptake was higher in aneurysm when compared to
control aorta (log2TBRmax 1.712±0.560 vs. 1.314±0.489; difference 0.398 (95% CI
0.057, 0.739), p=0.023), or to non-aneurysmal aorta in patients with AAA
(log2TBRmax 1.647±0.537 vs. 1.332±0.497; difference 0.314 (95% CI 0.0685, 0.560),
p=0.004). An ex vivo study was performed on aneurysm and control tissue, which
demonstrated that 18F-NaF uptake on microPET-CT was higher in the aneurysm
hotspots and higher in aneurysm tissue compared to control tissue. Histological
analysis suggested that 18F-NaF was highest in areas of focal calcification and
necrosis. In an observational cohort study, aneurysms were stratified by tertiles of
TBRmax in the MDS and followed up for 510±196 days, with 6 monthly serial
ultrasound measurements of diameter. Those in the highest tertile of tracer uptake
expanded more than 2.5 times more rapidly than those in the lowest tertile (3.10
[3.58] mm/year vs. 1.24 [2.41] mm/year, p=0.008) and were also more likely to
experience repair or rupture (15.3% vs. 5.6%, log-rank p=0.043). In multivariable
analyses, 18F-NaF uptake on PET-CT emerged as an independent predictor of AAA
expansion (p=0.042) and rupture or repair (HR 2.49, 95% CI1.07, 5.78; p=0.034),
even when adjusted for age, sex, body mass index, systolic blood pressure, current
smoking and, crucially, aneurysm diameter.
Conclusion
These are the largest USPIO MRI and PET-CT studies in AAA disease to date and
the first to investigate 18F-NaF. Both USPIO MRI and 18F-NaF PET-CT are able to
predict AAA expansion and the composite of rupture and repair, with 18F-NaF PETCT
emerging as the first imaging biomarker that independently predicts expansion
and AAA events, even after adjustment for aneurysm diameter. This represents an
exciting new predictor of disease progression that adds incremental value to standard
clinical assessments. Feasibility and randomised clinical trials are now required to
assess the potential of this technique to change the management and outcome of patients with AAA
Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans
- Author
- Abbasi Z
- Abdul-Hamid M Akhlil
- Abel Paul D
- Abrams Paul H
- Adab Fawzi A
- Adamson Andrew
- Adeyoju A
- Adolfson Jan
- Afzal Naveed
- Ahiaku Ernest K N
- Ahmed Munir
- Al Sudani Mohammed L
- Al-Samarraie Amir S M
- Al-Samerraie [Unknown]
- Al-Singary Waleed
- Al-Sudani [Unknown]
- Alcock Christopher
- Alexander Kimberly
- Ali Zulfiqar
- Almond David J
- Alonzi Roberto
- Aly Markus
- Amin Al Olama Ali
- Anderson John
- Andrews Henry
- Andrews Steven
- Anjum Iqbal
- Anson Ken
- Anyamene Nicola A
- Apakama Ike
- Aparcia F
- Archbold J A A
- Arndt Volker
- Ash D
- Ashford Richard F U
- Auvinen Anssi
- Azzabi A
- Badenoch David
- Bahl Amit
- Bailey Karen
- Bailey M J
- Ball Andrew J
- Banerjee G
- Barber Jim
- Barber N
- Baria [Unknown]
- Barnes Douglas G
- Barros-Silva Joao
- Barwell Julian
- Bashir J
- Basu Pradip
- Bates Christopher A
- Batra Jyotsna
- Bax N A
- Baxter-Smith D
- Bdesha Amar
- Beacock Christopher J M
- Beaney Ronald P
- Beard Ralph
- Beatty John D
- Beck Rupert
- Beese Gail
- Beesley Sharon
- Bell C Richard W
- Bellringer James
- Benlloch Garcia Sara
- Benson Richard
- Beresford [Unknown]
- Bevis Christopher R A
- Bhana Rajanee
- Bhanot S
- Bhatnagar A
- Bhatt R I
- Birch Brian
- Birtle Alison
- Bishop M
- Biyani C Shekhar
- Blacklock A R E
- Blades Rosemary
- Bliss Peter
- Bloomfield David J
- Boddy S
- Bollina Prasad
- Bonnington Sue
- Booth C M
- Bose Pradeep
- Bott Michael C
- Bottomley David
- Boucher Nigel R
- Bowen J
- Bower Mark
- Bowsher W G
- Boyd P J R
- Bradshaw Lynne
- Bramble F James
- Brenner Hermann
- Brewster Simon F
- Briggs Tim
- Brock Cathryn
- Brock Sue
- Bromage Stephen
- Broms Michael
- Brough Richard
- Brown Andrew A
- Brown Paul
- Brown Paul M
- Brown Richard
- Brown Stephen
- Browning Tony J
- Bryan N
- Burgess Neil A
- Burns-Cox Nicholas
- Butterbach Katja
- Butterworth Paul C
- Cahill D
- Callaghan P S
- Calleary John
- Calleja M
- Calman Frances
- Camilleri Philip
- Campbell Alister
- Cannon Andrea
- Cannon-Albright Lisa
- Carnell Dawn M
- Carr T W
- Carter Adam C
- Carter Charles J M
- Carter Simon
- Castle Bruce M
- Catto James
- Cavalli-Bjoerkman Carin
- Chadwick David
- Chahal Rohit
- Chakraborti P
- Chappell [Unknown]
- Charig C
- Chetiyawardana Anula D
- Chilton Christopher
- Chinegwundoh F I
- Chong Irene
- Choudhury Ananya
- Chow Wai-Man
- Christmas Timothy J
- Christova Svetlana
- Churn Mark J
- Cieza-Borrella Clara
- Clarke Noel W
- Clavijo-Eisele Jorge
- Clements Judith A
- Coe M
- Coetzee Gerhard A
- Cohen N P
- Coker C
- Cole David J
- Cole O
- Cole Trevor
- Collins Angus
- Collins Gerald
- Collinson Matthew
- Conn I
- Connell C
- Conti David V
- Cook Audrey
- Cook Margaret
- Cooke Peter
- Cooksey Graeme
- Coombs L
- Cooper Debbie
- Copland Robert F
- Cornaby Andrew J
- Cornford P A
- Corolis [Unknown]
- Corr John
- Costello C B
- Coull Mrs N
- Cowan Richard
- Cox Angela
- Cox Robert
- Coyle C
- Crew Jeremy
- Crisp John C
- Cross W
- Cruger Dorthe
- Crundwell Malcolm
- Cummings [Unknown]
- Cybulski Cezary
- Dadaev Tokhir
- Dahar Nazeer
- Daniel Francis N
- Darrad J
- Daruwala Pallon
- Das Gautam
- Datta Shibendra
- Davidson S
- Davies Joseph
- Davis Michael
- Davison Owen W
- Dawkins Guy
- Dawson Chris
- De Bolla Alan R
- Dearnaley David
- Desai Ken M
- Deutsch George P
- Dick John
- Dickinson Andrew J
- Dickson Jeanette
- Dikov Tihomir
- Dinneen Michael
- Dixit Sanjay
- Dobbs H Jane
- Doble A
- Doble Andrew
- Dodds David
- Doherty Alan
- Donaldson P
- Donovan Jenny L
- Dooldeniya M
- Douglas S Fiona
- Down Liz
- Drake [Unknown]
- Duchesne Gill M
- Duffy Peter
- Dunn Michael
- Dunsmuir W D
- Durkan Garrett
- Durrani Sajid K
- Easton Douglas
- Eaton Alan C
- Eccles Diane
- Eckert Allison
- Eddy B
- Eden C D
- Edwards J
- Eeles Rosalind A
- El-Modir A
- Elkabir Jeremy
- Elliott Emma
- Elliott P Tony
- Ellis B W
- Ellis R
- Elves Andrew W S
- Elwell Christine
- Emberton Mark
- Emmerson Louise
- England Roland C D
- Errington R D
- Evans D Gareth
- Falconer Alison
- Fawcett Derek
- Featherston C
- Featherstone Carolyn J
- Feggetter Jeremy
- Ferguson C
- Fermont D
- Ferro Michael
- Fisher Cyril
- Fitzgerald Liesel
- Fitzgerlad Liesel M
- Fletcher Matthew
- Folkes A
- Ford Trevor F
- Foster Paul W
- Franks Kevin N
- Freedman Mathew
- Frim Olivera
- Gale Joanna
- Gallegos Christopher
- Gelister James S
- George Anne
- Ghana [Unknown]
- Gibbs Stephanie
- Gilbert Hugh
- Giles Graham G
- Gillatt David
- Glaholm John
- Glass Jonathan M
- Glenister James
- Goode Thomas D
- Gordon E M
- Govindasami Koveela
- Gower Richard L
- Graham John
- Green Damian
- Greenland Jonathan
- Grieve Robert
- Griffiths Thomas R L
- Gronberg Henrik
- Gujral Sandy
- Gupta Nishi
- Gurun Riza Murat
- Gustafsson Sven
- Guy Michelle
- Guy Peter J
- Haiman Christopher A
- Haldar Neil
- Halder N
- Haley James
- Hamdy F C
- Hamdy Freddie
- Hamilton C
- Hammonds John
- Hampson S J
- Hanbury Damien C
- Hardman P D John
- Harland Stephen J
- Harney John M
- Harper Peter
- Harris D
- Harris Sarah
- Harrison G S M
- Harriss D R
- Harvey-Hills N
- Hawkyard Simon
- Hazel Steve
- Hazelett Dennis J
- Heath Catherine M
- Heathcote Peter
- Hehir Michael
- Hellawell Giles O
- Henderson Brian E
- Hendry David
- Henley Mike
- Henrique Rui
- Henry Ann
- Herbert Pippa
- Herkommer Kathleen
- Hetherington John
- Hickish Tamas
- Hicks James A
- Hilman Serena
- Hindley Richard
- Hindmarsh John R
- Hines John
- Hingorani M
- Ho Edwin T S
- Hodgson Shirley
- Hoffman U
- Holden David
- Holding Peter
- Hollingdale A
- Hollins Graham W
- Holmes Simon A V
- Holt Sarah
- Hopper John L
- Horan Gail
- Horwich Alan
- Hoskin Peter
- Howell Graham P
- Howson Joanne
- Hrouda D
- Huddart Robert
- Hudson Liz
- Hughes Michael
- Hughes Owen
- Hughes Rob
- Humber Caroline
- Iacovou John W
- Ibrahim A
- Inglis John A
- Irving Stuart
- Irwin C
- Iversen Peter
- Izatt Louise
- Izegbu Victor
- Jameel Basharat
- James Michael J
- James N
- James R Lester
- Javle Pradip
- Jenkins P
- Jhavar Sameer
- Johansson Jan-Erik
- Jones Chris R
- Jones David A
- Jones Gareth
- Jones Mandy
- Joseph J
- Joss Shelagh
- Jugurnauth-Little Sara
- Kachakova Darina
- Kaisary Amir
- Kaliski Alexandre L
- Kaneva Radka
- Kapur G
- Karim O
- Karlsson Ami
- Karp Stephen J
- Kedda Mary-Anne
- Keeley F X
- Kelkar Anand R
- Kelleher J P
- Kelly John
- Kenwrick Sue
- Kerr Kris
- Key Tim J
- Khan F
- Khaw Kay-Tee
- Khoo Vincent
- Kibel Adam S
- Kierzek Andrzej
- Kimber Rachel M
- Kinder R
- Kirby Roger S
- Kirk David
- Kirkbride Peter
- Kirollos Magdi M
- Klarskov Peter
- Kluzniak Wojciech
- Kockelbergh Roger
- Koenig Philip C W C
- Kooiman Gordon G
- Koreich O
- Kote-Jarai Zsofia
- Koupparis Anthony
- Kourah Mohamed
- Kraus Sigurd
- Kujala Paula
- Kujawa Magda L
- Kulkarni Ravi
- Kumar M
- Kumar Rajeev
- Kunkler Ian H
- Kynaston H
- Kynaston Howard
- Lachlan Katherine L
- Laing Robert
- Lalloo Fiona
- Lancashire M
- Lane Athene
- Langley Stephen E M
- Laniado Marc
- Larner T R
- Lau Maurice W
- Lawrence W T
- Lawson Anne
- Le Roux Pieter J
- Leader Mary
- Lee A
- Lee J O
- Lee L
- Lemburger R John
- Lennon Teresa
- Leone Priscilla
- Leongamornlert Daniel
- Lester Jason
- Leung Hing
- Lewis D Christopher
- Lewis J
- Li Qiuyan
- Lim Hui-Yi
- Lin Hui-Yi
- Liston Thomas
- Livni Naomi
- Livsey Jacqueline
- Lloyd S
- Locke Imogen
- Lodge Richard
- Logue John
- Longmuir Mark
- Lophatananon Artitaya
- Lophatonanon Artitaya
- Lubinski Jan
- Lucas Malcolm G
- Luedeke Manuel
- Luscombe C J
- Lydon Anna
- Lynch Michael
- Lynn Naing N K
- Lyons Norma
- MacDermott James P A
- Macdonagh Ruaraidh P
- Macdonald [Unknown]
- Madaan Sanjeev
- Madhava Kudingila R
- Maeaettaenen Liisa
- Maguire Joseph
- Maher E R
- Mahmood Rana
- Maia Sofia
- Maier Christiane
- Mair Graeme H M
- Malone Greg
- Malone Peter R
- Mangar Stephen A
- Mantle Mark
- Mark I
- Marsden Gemma
- Mason M D
- Mason Malcolm
- Mason Robert
- Matanhelia [Unknown]
- Matenhelia Shyam
- Matthews Philip N
- McAleese J
- McBride Donna
- Mcdonnell Shannon K
- McDonnell Shannon K
- McFarlane Jonathan
- McGrath [Unknown]
- McIlhenny Craig
- McInerney Paul
- McIntosh Gregor
- McKinna F
- McLaren Duncan
- McLarty Esther
- McMenemin Rhona
- McNeill Alan
- McNicholas T A
- Meddings Robert N
- Mee A David
- Melcher Lucinda
- Memon [Unknown]
- Menzes Pravin
- Michael Agnieszka
- Miller Marek
- Mills Robert
- Mitchell S
- Mitev Vanio
- Mithal Natasha
- Mitkova Atanaska
- Mitra Anita
- Mobb Gillian E
- Moffat Leslie E F
- Mokete [Unknown]
- Money-Kyrle Julian
- Montgomery Bruce
- Moody Hilary
- Moody Martin P
- Morgan Angela
- Morley Roland
- Morris Sean B
- Morrison Patrick
- Mort Diana
- Mostafid Amir H
- Motiwala Hanif
- Mufti Gulzar
- Muir Gordon
- Muir Kenneth
- Mumtaz Faiz
- Murphy Michael
- Murray Alexandra
- Murray Keith W
- Murrell Shirley
- Murtola Teemu
- Muthukumar D
- Naerger Harry
- Namasivayam Siva
- Nargund Vinod
- Nawrocki [Unknown]
- Neal David E
- Neilson Donald
- Nethersell A
- Newby Jacqueline C
- Newman Hugh
- Newton R
- Nielsen Sune F
- Nordestgaard BĂžrge G
- O'Boyle P J
- O'Brien J
- O'Brien Tim S
- O'Donnell H
- O'Donoghue E
- O'Donoghue Neil
- O'Reilly P
- O'Rourke J S
- O'Sullivan Joe
- O'Sullivan Patricia
- Oakley Neil
- Ogden Chris
- Ohja Hemant
- Oliver Tim
- Omara Tracy
- Ong Eng K
- Osborn David
- Ostler Peter
- Owen J
- Palfrey Edward
- Panades Miguel
- Panakis Niki
- Pancharatnam M
- Pandha Hardev
- Pantelides Michalakis L
- Panwar U
- Parikh Omi
- Park Hyun
- Park Jong Y
- Parker Chris
- Parker Christopher H
- Parys Bohdan T
- Pascoe Sarah
- Pashayan Nora
- Patel Anup
- Paterson Joan
- Pathack S
- Pati Jhumur
- Patterson Helen
- Pattu [Unknown]
- Paul A
- Paul Alan
- Paulo Paula
- Payne Heather
- Peake David
- Pedersen John
- Pedley I
- Pengelly A
- Peracha Amjad M
- Perry Matthew
- Persad Raj
- Peters John
- Pharoah Paul
- Philp N H
- Philp T
- Pickering Lisa M
- Pigott Katharine
- Pinto Pedro
- Plail R
- Plowman P Nicholas
- Pocock Richard D
- Pope A J
- Popert Rick
- Popov Elenko
- Porter Tim
- Potter John M
- Pow-Sang Julio
- Powell Christopher
- Powell Philip
- Powles Thomas B
- Prasad Krishna
- Prasad Seshadri Sri
- Prejbisz J W
- Prescott Stephen
- Protheroe Andrew
- Qureshi Khaver N
- Raby Nigel
- Radlein Selina
- Ragavan Narasimhan
- Raju Palaniappa G S
- Ramachandra Prakash B
- Raman R
- Rane Abhay
- Rankin Julia
- Rao Y
- Ratan Hari L
- Ravi Ramachandran
- Ravishankar K
- Read [Unknown]
- Reddy Paul J
- Rimington Peter R
- Rinckleb Antje
- Rincon Maria
- Riska Shaun
- Ritchie Peter A
- Roberts J Trevor
- Robertson Andrew
- Robinson Angus
- Robinson Anne C
- Robinson Lee Q
- Rochester Mark A
- Roder Andreas
- Rogers P B
- Rosario Derek
- Rosenbaum Tomas P
- Rothwell Neil
- Rowbotham Carl
- Rowe [Unknown]
- Rowley Kathryn
- Ruddy Deborah
- Rundle John
- Russell John M
- Ryan P G
- Sabharwal A
- Saggar Anand K
- Samanci Ali
- Sangar Vijay K
- Santos Joana
- Saunders Edward J
- Saunders Pamela
- Sawyer Emma J
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- Schleutker Johanna
- Schumacher Fredrick
- Schwaibold Hartwig
- Scoble John E
- Scrase Christopher
- Selim [Unknown]
- Sellers Thomas
- Sells Henry
- Sethia Krishna K
- Severi Gianluca
- Shackley David C
- Shaffer [Unknown]
- Shah Nihil
- Shakespeare D
- Shanley Sue
- Sharma Neerah K
- Sheehan Denise J
- Sherwin Elizabeth
- Shum Poh Lin
- Side Lucy
- Sidek Norma
- Signorello Lisa B
- Sikora Karol
- Simcock R
- Sinclair Andrew M
- Singh Pravin
- Siva M
- Slavov Chavdar
- Smith James
- Smith Michael F
- Sokal Michael
- Sole Graham M
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- Spiers Alexander
- Spurdle Amanda
- Sreenivasan Thiagarajan
- Srihari Narayanan N
- Srinivasan [Unknown]
- Sriram Rajagopalan
- Staffurth John N
- Stanford Janet L
- Stattin Paer
- Stegmaier Christa
- Stephens Sarah
- Stewart D
- Stockdale Andrew
- Stott Mark A
- Stower M J
- Strachan John R
- Stuart Nicholas S A
- Sugden Elaine
- Summerton Duncan
- Sundar Santhanam
- Sundaram S K
- Suresh Gokarakonda
- Susnerwala Shabbir
- Swami Kuchibhotla S
- Symons Stephanie J
- Syndikus Isabel
- Taari Kimmo
- Tahir Saad
- Tammela Teuvo L
- Tammela Teuvo L J
- Tanquay J
- Taylor J W
- Taylor John W
- Teixeira Manuel R
- Terry T
- Thibodeau Stephen N
- Thomas Robert J
- Thomas Stephen A
- Thompson Alan
- Thompson Pauline
- Thomson Alastair H
- Thurston A
- Tidball Sarah
- Tillmans Lori
- Tilsley Owen
- Tindall Stuart F
- Tipples K
- Tong [Unknown]
- Toussi Hamid
- Toy Elizabeth W
- Travis Ruth C
- Trembath Richard C
- Tulloch David N
- Turner Kevin J
- Turner Megan
- Tweedle James
- Tymrakiewicz Malgorzata
- Tyrell C J
- Umez-Eronini N
- Urwin Graeme H
- Vale Justin A
- Van As [Unknown]
- Van As Nicholas
- Vasanthan Subramaniam
- Vesey Sean
- Vilarino-Varela Maria
- Violet John
- Virdi Jaspal
- Viñuela Ana
- Vlahova Aleksandrina
- Vogel Walther
- Wade Robert
- Wahlfors Tiina
- Waite Katherine
- Walker E M
- Walker Roger
- Wallace David M A
- Wallinder Hans
- Wang Liang
- Watkin Nicholas A
- Watson M E
- Waxman J H
- Waymont Brian
- Weaver Andrew
- Webb Ralph J
- Wedderburn Andrew
- Weischer Maren
- Wells Paula
- Wemyss-Holden G D
- Weston P M T
- Wheatley Duncan
- Whelan P
- Whillis D
- Whitmore Ian
- Wiklund Fredrik
- Wilde Adam D
- Wiles Vicki
- Wilkins Marie
- Wilkinson Rosemary
- Williams John H
- Williams Simon
- Willis Michael
- Wills Michael I
- Wilson J R
- Wilson Richard
- Winkler Mathias H
- Wise Marcus
- Wokozorczyk Dominika
- WokoĆorczyk Dominika
- Wood Glenn
- Woodhams Simon
- Woodhouse C
- Woodward Cathryn
- Woolf [Unknown]
- Woolfenden K A
- Worlding Jane
- Wright Mark
- Wu Huihai
- WYLIE [Unknown]
- Wylie James P
- Wynne Chris
- Yeadon Trina
- Zachariah Babu
- Zang Angelika
- Zarkar A
- Zheng Wei
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2015
- Field of study
Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have
fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in
25 723 PrCa cases and 26 274 controls of European ancestry. We detected evidence for multiple independent signals at 16
regions, 12 of which contained additional newly identified significant associations. A single signal comprising a spectrum of
correlated variation was observed at 39 regions; 35 of which are now described by a novel more significantly associated lead SNP,
while the originally reported variant remained as the lead SNP only in 4 regions. We also confirmed two association signals in
Europeans that had been previously reported only in East-Asian GWAS. Based on statistical evidence and linkage disequilibrium
(LD) structure, we have curated and narrowed down the list of the most likely candidate causal variants for each region.
Functional annotation using data from ENCODE filtered for PrCa cell lines and eQTL analysis demonstrated significant
enrichment for overlap with bio-features within this set. By incorporating the novel risk variants identified here alongside the
refined data for existing association signals, we estimate that these loci now explain âŒ38.9% of the familial relative risk of PrCa,
an 8.9% improvement over the previously reported GWAS tag SNPs. This suggests that a significant fraction of the heritability of
PrCa may have been hidden during the discovery phase of GWAS, in particular due to the presence of multiple independent
signals within the same regio
Genome-wide Analyses Identify KIF5A as a Novel ALS Gene
- Author
- A. Nazli Basak
- A. Nazli Basak
- Aaron D. Gitler
- Aaron D. Gitler
- Aaron G. Day-Williams
- Adriano Chio
- Adriano ChiĂČ
- Ahmad Al Kheifat
- Alan E. Renton
- Albert C. Ludolph
- Alberto Garcia Redondo
- Alberto GarcĂa-Redondo
- Alberto M. Rivera
- Aleksey Shatunov
- Aleksey Shatunov
- Alessandra Chesi
- Alessandro Arosio
- Alex LeNail
- Alexander LeNail
- Alexander Sherman
- Alexis Brice
- Alfredo Iacoangeli
- Alya R. Raphael
- Amelia Conte
- Ammar Al-Chalabi
- Ammar Al-Chalabi
- Andrea Calvo
- Andrea Calvo
- Andrea Malaspina
- Andrea Malaspina
- Andrea Swenson
- Andrew B. Singleton
- Andrew King
- Andrew S. Allen
- Angela L. Jones
- Angelo Pirisi
- Anna Ticca
- Anne Cooley
- Anneloor L.M.A. ten Asbroek
- Annelot Dekker
- Antonia Ratti
- Antonia Ratti
- Antonino Cannas
- Antonio Canosa
- Antonio Fasano
- Antonio Ilardi
- Antonio Milia
- Antonio Petrucci
- Aoife Kenna
- Athina Soragia Gkazi
- Aude Nicolas
- Avinash Abhyankar
- Avindra Nath
- Barbara Castellotti
- Barbara Poletti
- Bas Middelkoop
- Bas Middelkoop
- Braden E. Boone
- Bradley N. Smith
- Brendan J. Kenna
- Brian J. Krueger
- Brittany N. Lasseigne
- Bryan J. Traynor
- Carla Caredda
- Carla Pani
- Carlayne Jackson
- Carlo Ferrarese
- Caroline Vance
- Chris Shaw
- Christian Lunetta
- Christian Lunetta
- Christine Clayman
- Christopher B. Brady
- Christopher E. Shaw
- Cinzia Bertolin
- Cinzia Femiano
- Cinzia Gellera
- Cinzia Gellera
- Cinzia Tiloca
- Cinzia Tiloca
- Claire Troakes
- Claudia Caponnetto
- Claudia Caponnetto
- Claudia Colombrita
- Claudia Ricci
- Clive N. Svendsen
- Clive N. Svendsen
- Corey McMillan
- Cristiane de Araujo Martins Moreno
- Cristina Cereda
- Cristina Cereda
- Cristina Moglia
- Daniel J. MacGowan
- Daniel J.L. MacGowan
- Daniela Corongiu
- Daniela Loi
- David B. Goldstein
- David B. Goldstein
- David B. Goldstein
- David J. Stone
- David Lacomis
- David Walk
- Dena G. Hernandez
- Denis C. Bauer
- Dhruv Sareen
- Dhruv Sareen
- Diane McKenna-Yasek
- Diane McKenna-Yasek
- Edward B. Lee
- Efthimios Dardiotis
- Ekaterina Rogaeva
- Elizabeth T. Cirulli
- Emanuela Costantino
- Emilien Bernard
- Emily Baxi
- Emily Baxi
- Emmeline Lagrange
- Enzo Ortu
- Eran Hornstein
- Ericka Simpson
- Ericka Simpson
- Erik P. Pioro
- Erik Pioro
- Ernest Fraenkel
- Ernest Fraenkel
- Ernest Fraenkel
- Eva L. Feldman
- Evadnie Rampersaud
- Evadnie Rampersaud
- Fabio Giannini
- Fabiola De Marchi
- Fabrizio Pisano
- Fabrizio Salvi
- Fabrizio Salvi
- Faraz Faghri
- Federico Casale
- Federico Verde
- Federico Verde
- Francesca L. Conforti
- Francesca L. Conforti
- Francesca Trojsi
- Francesca Trojsi
- Francesco Landi
- Francesco Marrosu
- Francesco O. Logullo
- Francesco O. Logullo
- Franco Taroni
- Franco Taroni
- Frank Baas
- Frank Baas
- Freya Kamel
- Gabriele Mora
- Gabriele Mora
- Gabriele Siciliano
- Gabriella Restagno
- Gang Wu
- Gang Wu
- Garth A. Nicholson
- George Manousakis
- Giacomo P. Comi
- Giacomo P. Comi
- Giancarlo Logroscino
- Gianluca Floris
- Gianluigi Mancardi
- Gianni SorarĂč
- Gianni SorarĂč
- Gijs Tazelaar
- Gioacchino Tedeschi
- Giorgia Querin
- Giovanni Piccirillo
- Giuseppe Borghero
- Giuseppe Borghero
- Giuseppe Fuda
- Giuseppe Lauria
- Giuseppe Lauria
- Giuseppe Lauria Pinter
- Giuseppe Marangi
- Giuseppe Marangi
- Giuseppe Marrali
- Glenn Gerhard
- Gregory A. Cox
- Gregory M. Cooper
- Guy A. Rouleau
- Guy A. Rouleau
- Gwendal Lemasson
- GĂ©rard Besson
- Hannah A. Pliner
- Hannu Laaksovirta
- Hemali Phatnani
- Hemali Phatnani
- Hisham Hamdalla
- Ian P. Blair
- Ian P. Blair
- Ilaria Bartolomei
- Irene Ossola
- Isabella Fogh
- Isabella Fogh
- Isabella L. Simone
- Isabella Simone
- Isabelle Le Ber
- J. Paul Taylor
- J. Paul Taylor
- J. Raphael Gibbs
- Jack R. Wimbish
- Jacob McCauley
- Jacqueline de Belleroche
- James Broach
- James Caress
- James D. Berry
- James D. Berry
- James D. Berry
- James R. Broach
- Jan H. Veldink
- Jan Veldink
- Janel O. Johnson
- Janice A. Dominov
- Janine Kirby
- Jaya Trivedi
- Jeannine Heckmann
- Jeffrey D. Rothstein
- Jeffrey D. Rothstein
- Jeffrey Statland
- Jennifer A. Fifita
- Jennifer E. Van Eyk
- Jenny Van Eyk
- Jessica Mandrioli
- Jessica Mandrioli
- Jesus Mora Pardina
- JesĂșs Esteban-PĂ©rez
- JesĂșs S. Mora
- Jinghui Zhang
- Jinhui Ding
- Joanne Wuu
- Joanne Wuu
- Jochen H. Weishaupt
- John D. Eicher
- John E. Landers
- John Ealing
- John F. Staropoli
- John Hardy
- John Landers
- John M. Ravits
- John M. Ravits
- John P. Carulli
- John Q. Trojanowski
- John Ravits
- Johnathan Cooper-Knock
- Joke J.F.A. van Vugt
- Joke van Vugt
- Jonathan Cooper-Knock
- Jonathan D. Glass
- Jonathan D. Glass
- Jonathan D. Glass
- Jonathan Glass
- Jonathan Katz
- Jonathan Keebler
- Jonathan Mill
- Joshua Dubnau
- Joshua T. Geiger
- José Luis Muñoz-Blanco
- Juan C. Troncoso
- Julia Kaye
- Julia Kaye
- Julien Couthouis
- Justin Kwan
- Kalliopi Marinou
- Karen E. Morrison
- Karen Morrison
- Katherine B. Sims
- Katie C. Sidle
- Kelly Gwathmey
- Kelly L. Williams
- Kelly L. Williams
- Kevin B. Boylan
- Kevin Kenna
- Kevin Mouzat
- Kevin Mouzat
- Kevin P. Kenna
- Kevin Talbot
- Kristel R. Van Eijk
- Kristel van Eijk
- Lauren Elman
- Leandro Lima
- Leandro Lima
- Leo Wang
- Leonard H. van den Berg
- Leonard van den Berg
- Leslie D. Parish
- Leslie M. Thompson
- Leslie M. Thompson
- Leslie M. Thompson
- Letizia Mazzini
- Letizia Mazzini
- Liberty Jenkins
- Liisa Myllykangas
- Lilja Jansson
- Lindsay L. Waite
- Lorena Mosca
- Lorne Zinman
- Luca Maderna
- Lucia Corrado
- Lucia Corrado
- Lucie Bruijn
- Lucio Tremolizzo
- Ludo Van Den Bosch
- Luigi Ferrucci
- Lyle W. Ostrow
- Lyle W. Ostrow
- Maarten Kooyman
- Maarten Kooyman
- Mamede de Carvalho
- Mamede de Carvalho
- Marc Gotkine
- Marcella Zollino
- Marco Barberis
- Marco Luigetti
- Margherita Capasso
- Margherita Capasso
- Maria Giovanna Marrosu
- Maria Rita Murru
- Maria Rosaria MonsurrĂČ
- Marialuisa Santarelli
- Marielle Wallace
- Mario Sabatelli
- Mario Sabatelli
- Marka Van Blitterswijk
- Markus Weber
- Markus Weber
- Martin R. Turner
- Mary Kay Floeter
- Massimiliano Filosto
- Massimo Corbo
- Matthew B. Harms
- Matthew B. Harms
- Matthew B. Harms
- Matthew Kiernan
- Matthieu Moisse
- Mattieu Moisse
- Maura Brunetti
- Maura Pugliatti
- Maurizio Grassano
- Maurizio Inghilleri
- Maurizio Melis
- Mauro Ceroni
- Mayana Zatz
- Meraida Polak
- Merit Cudkowicz
- Merit Cudkowicz
- Michael A. Van Es
- Michael Benatar
- Michael Benatar
- Michael C. Zody
- Michael van Es
- Michele Benigni
- Michelle Penny
- Miguel Mitne Neto
- Mike A. Nalls
- Miko Valori
- Molly G. Hammell
- Natalie A. Murphy
- Natalie A. Twine
- Nathalie Guy
- Neil A. Shneider
- Neil A. Shneider
- Neil A. Shneider
- Neil W. Kowall
- Nicholas J. Maragakis
- Nicholas J. Maragakis
- Nicola Fini
- Nicola Ticozzi
- Nicola Ticozzi
- Nicola Ticozzi
- Nikolaos A. Patsopoulos
- Nilo Riva
- Nilo Riva
- Noah Zaitlen
- null Shankaracharya
- Orla Hardiman
- Orla Hardiman
- Pamela J. Shaw
- Pamela Keagle
- Pamela Shaw
- Paola Carrera
- Paola Mandich
- Paola Origone
- Paolo Volanti
- Paolo Volanti
- Patrick A. Dion
- Patrick Vourch
- Patrizia Occhineri
- Pentti Tienari
- Peter Andersen
- Peter C. Sapp
- Peter C. Sapp
- Peter M. Andersen
- Philip Van Damme
- Philip van Damme
- Philippe Corcia
- Philippe Corcia
- Philippe Corcia
- Philippe Couratier
- Philippe Couratier
- Pierre Clavelou
- Pietro Fratta
- Pietro Fratta
- Quanli Wang
- Raffaella Tanel
- Rajeeva Lochan Musunuri
- Rebecca Schule
- Riccardo Sideri
- Richard Barohn
- Richard Bedlack
- Richard M. Myers
- Richard M. Myers
- Richard S. Bedlack
- Richard W. Orrell
- Rick A. Van der Spek
- Rick van der Spek
- Robert Bowser
- Robert Brown
- Robert H. Baloh
- Robert H. Baloh
- Robert H. Baloh
- Robert H. Baloh
- Robert H. Brown
- Roberta Puddu
- Roberto Del Bo
- Roger Pamphlett
- Rosa Rademakers
- Rosa Rademakers
- Rossella Spataro
- Roy H. Campbell
- Russell L. McLaughlin
- Russell McLaughlin
- Ruth Chia
- Safa Al-Sarraj
- Sampath Arepalli
- Samuel Maiser
- Sandra DâAlfonso
- Sandra DâAlfonso
- Sara Pulit
- Sara Rollinson
- Sebastian D. Hayes
- Sebastiano Cavallaro
- Seneshaw Asress
- Serena Lattante
- Serge Lumbroso
- Serge Lumbroso
- Shaida Khan
- Shawn E. Levy
- Siddharthan Chandran
- Siddharthan Chandran
- Silvana Penco
- Silvia Peverelli
- Simon D. Topp
- Sitharthan Kamalakaran
- Slavé Petrovski
- Sonia Messina
- Sonja W. Scholz
- Stacia K. Wyman
- Stacia Wyman
- Stanley Appel
- Stanley H. Appel
- Stefan M. Pulst
- Stefan M. Pulst
- Stefania Battistini
- Stefania Battistini
- Stefania Cammarosano
- Stefania Corti
- Stefania Cuccu
- Stefania Tranquilli
- Stefania Tranquilli
- Stella Gagliardi
- Stephan ZĂŒchner
- Stephen A. Goutman
- Stephen Goutman
- Stephen J. Kolb
- Stephen J. Kolb
- Stephen Newhouse
- Steve Finkbeiner
- Steven Finkbeiner
- Steven Finkbeiner
- Stuart Pickering-Brown
- Sumaira Hussain
- Summer B. Gibson
- Summer Gibson
- Summer Gibson
- Susana Pinto
- Suvankar Pal
- Suvankar Pal
- Tea B. Cau
- Ted Burns
- Terry D. Heiman-Patterson
- Terry Heiman-Patterson
- Thomas Meitinger
- Tim Harris
- Tim Harris
- Tim M. Strom
- Timothy M. Miller
- Timothy M. Miller
- Timothy M. Miller
- Timothy M. Miller
- Timothy M. Miller
- Tiziana Colletti
- Tom Maniatis
- Travis L. Dunckley
- Uday Shankar Evani
- Umberto Manera
- Valeria Piras
- Vincent Meininger
- Vincenzo La Bella
- Vincenzo La Bella
- Vincenzo Silani
- Vincenzo Silani
- Vincenzo Silani
- Vivian Drory
- Vivian E. Drory
- Viviana Pensato
- Vivianna M. Van Deerlin
- Vivianna M. Van Deerlin
- VĂ©ronique Danel
- Wendy K. Chung
- William Camu
- William Camu
- William Sproviero
- Wim Robberecht
- Wim Robberecht
- Winnie W. Xin
- Winston Hide
- Wouter van Rheenen
- Wouter van Rheenen
- Ximena Arcila-Londono
- Yevgeniya Abramzon
- Yi-Fan Lu
- Yuen So
- Yujun Han
- Zachary Simmons
- Zachary Simmons
- Zachary Simmons
- Zhong Ren
- Publication venue
- Publication date
- 01/01/2018
- Field of study
To identify novel genes associated with ALS, we undertook two lines of investigation. We carried out a genome-wide association study comparing 20,806 ALS cases and 59,804 controls. Independently, we performed a rare variant burden analysis comparing 1,138 index familial ALS cases and 19,494 controls. Through both approaches, we identified kinesin family member 5A (KIF5A) as a novel gene associated with ALS. Interestingly, mutations predominantly in the N-terminal motor domain of KIF5A are causative for two neurodegenerative diseases: hereditary spastic paraplegia (SPG10) and Charcot-Marie-Tooth type 2 (CMT2). In contrast, ALS-associated mutations are primarily located at the C-terminal cargo-binding tail domain and patients harboring loss-of-function mutations displayed an extended survival relative to typical ALS cases. Taken together, these results broaden the phenotype spectrum resulting from mutations in KIF5A and strengthen the role of cytoskeletal defects in the pathogenesis of ALS.Peer reviewe
The genetic architecture of the human cerebral cortex
- Author
- Adams Hieab H H
- Adams Hieab H H
- Agartz Ingrid
- Ahlijanian Michael
- Ahmad Shahzad
- Ainscough Susan
- Aisen Paul
- Albers Colleen S
- Albert Marilyn
- Alhusaini Saud
- Allard Joanne
- Almeida Marcio A A
- AlnĂŠs Dag
- Alvim Marina K M
- Ames David
- Ames David
- Amin Najaf
- Amlien Inge K
- Amouyel Philippe
- Ances Beau
- Anderson Karen
- Anderson Tim J
- Andersson Micael
- Andreassen Ole A
- Andreassen Ole A
- Apostolova Liana
- Ard Tyler
- Arias-Vasquez Alejandro
- Armstrong Nicola J
- Armstrong Nicola J
- Arnedo Vanessa
- Arnold Steven E
- Artiges Eric
- Artiges Eric
- Ashley-Koch Allison
- Assaly Michele
- Assareh Amelia A
- Asthana Sanjay
- Atkins Joshua R
- Aydin Semiha
- Ayesa-Arriola Rosa
- Baca Marne
- Bachman David
- Banaschewski Tobias
- Barbot Alexis
- Barker Gareth
- Barone Paolo
- Bartha Rob
- Bartzokis George
- Bastin Mark E
- Bastin Mark E
- Bates Vernice
- Baune Bernhard T
- Becerra Mauricio
- Becker Andreas
- Becker James T
- Beckett Laurel
- Beckham Jean C
- Beiser Alexa S
- Belden Christine M
- Belger Aysenil
- Bell Karen L
- Berg Daniela
- Bergman Howard
- Bernard Manon
- Bernard Manon
- Bernick Charles
- Bernstein Matthew
- Beyer Frauke
- Bezivin-Frere Pauline
- Biondo Francesca
- Bis Joshua C
- Bis Joshua C
- Bishop Courtney
- Black Sandra
- Blangero John
- Blank Karen
- Bodge Courtney
- Bokde Arun
- Bonakdarpour Borna
- Boomsma Dorret I
- Borges-Neto Salvador
- Borowski Bret
- Borrie Michael
- Bralten Janita
- Brand Connie
- Brandabur Melanie
- Brandt Christine L
- Brewer James
- Brockington John
- Brodaty Henry
- Brodaty Henry
- Bromberg Uli
- Brooks David
- Brooks William M
- Brosch Jared R
- Brouwer Rachel M
- Brown Gregory G
- Bruehl Ruediger
- Brunner Han G
- Buckholtz Neil
- Buckner Randy L
- Budson Andrew E
- Buimer Elizabeth E L
- Buitelaar Jan K
- Burke Anna
- Burns Jeffrey M
- Bustillo Juan R
- BĂŒlow Robin
- BĂŒlow Robin
- BĂŒrger Christian
- BĂżchel Christian
- Cabrera Yuliana
- Cahn Wiepke
- Cairns Murray J
- Cairns Nigel J
- Calhoun Vince
- Cannon Dara M
- Capote Horacio
- Carlsson Cynthia M
- Carmichael Owen
- Carr Vaughan J
- Carrillo Maria
- Carroll Maria
- Carson Richard E
- Carter Raina
- Casaceli Cynthia
- Casalin Paola
- Caseras Xavier
- Caspell Chelsea
- Caspers Svenja
- Catafau Ana
- Cavalleri Gianpiero L
- Cedarbaum Jesse
- Cellar Janet S
- Celmins Dzintra
- Cendes Fernando
- Chahine Lama
- Chakravarty Mallar
- Chalker Alison
- Chao Steven
- Chen Kewei
- Chen Qiang
- Chertkow Howard
- Cheung Joshua W
- Chiang Gloria
- Ching Christopher R K
- Chowdhury Munir
- Chowdhury Sohini
- Chu Congying
- Cichon Sven
- Clark Christopher M
- Clark David
- Coffey Christopher
- Coleman Edward
- Colodro-Conde LucĂa
- Comery Thomas
- Conrad Gary
- Conrod Patricia
- Consortium CHARGE
- Consortium Enhancing NeuroImaging Genetics through Meta-Analysis
- Consortium EPIGEN
- Consortium IMAGEN
- Consortium SYS
- Correia Stephen
- Corvin Aiden
- Couvy-Duchesne Baptiste
- Crawford Karen
- Creech Mary L
- Crespo-Facorro Benedicto
- Crivello Fabrice
- Curran Joanne E
- D'Agostino Daniel
- Daedelow Laura
- Daiello Lori A
- Dale Anders M
- Dale Anders M
- Dalley Jeffrey
- Dalrymple-Alford John C
- Dalvie Shareefa
- Dang Mimi
- Dannlowski Udo
- Darin Abigail
- Davies Gareth E
- Davies Peter
- de Araujo TĂąnia K
- de Geus Eco J C
- de Zubicaray Greig I
- de Zwarte Sonja M C
- Deary Ian J
- Deary Ian J
- Debette Stephanie
- Debette Stephanie
- Decarli Charles
- DeCarli Charles
- Deeley Cheryl
- Degenhardt Franziska
- Delanty Norman
- DeMarco Kathryn
- den Braber Anouk
- Dennis Michelle F
- Depondt Chantal
- Desrivieres Sylvane
- DesriviĂšres Sylvane
- Dietsche Bruno
- Djurovic Srdjan
- Doan Nhat Trung
- Doherty Colin P
- Dohm Katharina
- Dolen Sara
- Donohoe Gary
- Donohue Michael
- Doody Rachelle S
- Dooley Eoin
- Doraiswamy P Murali
- Drost Dick
- Duara Ranjan
- Dubow Jordan S
- Dunlop Becky
- Egebjerg Jan
- Ehrlich Stefan
- El Khouli Riham
- Engelbrecht Hannah-Ruth
- Erk Susanne
- Espay Alberto
- Espay Kristy
- Espeseth Thomas
- Espiritu Ryan
- Faber Kelley
- Factor Stewart
- Fan Chun Chieh
- Fargher Kristin
- Farlow Martin R
- Fatica Parianne
- Fedko Iryna O
- Feldman Howard
- Fernandez Hubert
- Fernåndez Guillén
- Figurski Michal
- Filippi Irina
- Fillit Howard
- Fillmer Ariane
- Finger Elizabeth
- Fisher Simon E
- Flashman Laura A
- Fleisher Adam
- Fletcher Evan
- Flor Herta
- Flor Herta
- Foley Sonya F
- Fontaine Deborah
- Fontoura Paulo
- Ford Judith M
- Fornage Myriam
- Fornage Myriam
- Foroud Tatiana
- Foroud Tatiana M
- Forstner Andreas J
- Foster Eric
- Foster Norm
- Fox Nick
- Francks Clyde
- Frank Richard
- Frank Samuel
- Franke Barbara
- Franklin Erin
- Franz Carol E
- Frasier Mark
- Frouin Vincent
- Fröhner Juliane
- Fukunaga Masaki
- Gaikwad Mrunalini
- Galasko Douglas
- Garavan Hugh
- Garijo Daniel
- Garrett Melanie E
- Gauss Katharina
- Ge Tian
- Geldmacher David
- Gessert Devon
- Ghanbari Mohsen
- Giddaluru Sudheer
- Gigliotti Christina
- Gil Yolanda
- Gillespie Nathan A
- Glahn David C
- Gloer Katherine
- Goldman Aaron L
- Goldstein Bonnie S
- Goldstein David B
- Gollub Randy L
- Gowland Penny
- Gowland Penny A
- Grabe Hans J
- Grabe Hans Jörgen
- Grachev Igor D
- Graff-Radford Neill R
- Grasby Katrina L
- Green Davis Robert C
- Green Melissa J
- Green Robert C
- Green Robert C
- Greig-Custo Maria T
- Griffith Randall
- Grimmer Yvonne
- Groenewold Nynke A
- Grossman Hillel
- Grotegerd Dominik
- Gruber Oliver
- Gudnason Vilmundur
- Gunter Jeff
- Gurholt Tiril P
- Guthrie Stephanie
- Gutman Boris A
- Hake Ann Marie
- Hansell Narelle K
- Hardy Peter
- Hariri Ahmad R
- Harlan Sherry
- Harless Kelly
- Harris Mat
- Harris Mathew A
- Harrison Marc B
- Hart David
- Hartman Catharina A
- Harvey Danielle
- Hashimoto Ryota
- Haswell Courtney C
- Hauser Michael
- Hauser Robert
- Hawkins Keith A
- Hefti Franz
- Heidebrink Judith L
- Heindel Walter
- Heinz Andreas
- Heinz Andreas
- Heinzen Erin L
- Henskens Frans A
- Hergesheimer Lindsey
- Herms Stefan
- Hernando Raymundo
- Herring Scott
- Heslenfeld Dirk J
- Hetelle Joel
- Hewitt David L
- Heyn Chris Chinthaka
- Hibar Derrek P
- Hillegers Manon H J
- Himali Jayandra J
- Ho Beng-Choon
- Ho New Fei
- Hoehn David
- Hoekstra Pieter J
- Hofer Edith
- Hofer Edith
- Hoffmann Per
- Hoffmann Wolfgang U
- Hofman Albert
- Hogarth Penelope
- Hohmann Sarah
- Holleran Laurena
- Holmes Avram J
- Holsboer Florian
- Holtzman David
- Homuth Georg
- Hong L Elliot
- Honig Lawrence S
- Hoogman Martine
- Hopkins William D
- Hosein Chris
- Hosten Norbert
- Hottenga Jouke-Jan
- Hsiao John
- Hsiung Ging-Yuek Robin
- Hu Shu-Ching
- Hulshoff Pol Hilleke E
- Hunter Christine
- Hynes Mary L
- HĂ€usler Alexander N
- HĂ„berg Asta K
- Ihlenfeld Albrecht
- Ikeda Masashi
- Ikram M Arfan
- Ikram M Arfan
- Ing Alex
- Initiative Alzheimerâs Disease Neuroimaging
- Initiative Parkinsonâs Progression Markers
- Iranzo Alex
- Isaacson Stuart
- Isensee Corinna
- Ismail M Saleem
- Ittermann Bernd
- Jack Clifford R
- Jack Clifford R
- Jagust William
- Jahanshad Neda
- James Angela
- James Olga
- James Raymond
- Jang MiHyun
- Jankovic Joseph
- Janowitz Deborah
- Jansen Andreas
- Jansen Iris E
- Jennings Danna
- Jernigan Terry L
- Jia Tianye
- Jia Tianye
- Jian Xueqiu
- Jiang Jiyang
- Jicha Greg
- Jimenez Gustavo
- Jockwitz Christiane
- Johnson Kathleen
- Johnson Keith A
- Johnson Kris
- Johnson Nancy
- Johnson Patricia Lynn
- Johnson Sterling
- Jones David
- Jönsson Erik G
- Kahn René S
- Kanai Ryota
- Kantarci Kejal
- Karama Sherif
- Karama Sherif
- Karlawish Jason H
- Kasperaviciute Dalia
- Kass Joseph S
- Kataki Maria
- Kaufmann Tobias
- Kaye Jeffrey A
- Kelly Sinead
- Keltz Melanie
- Kennedy Martin A
- Kertesz Andrew
- Kerwin Diana
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- Kieburtz Karl
- Kielb Stephanie
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- Killiany Ronald
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- Kochunov Peter
- Koeppe Robert A
- Koleva Hristina
- KolskÄr Knut
- Koops Sanne
- Kopil Catherine
- Korecka Magdalena
- Kowalksi Nancy
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- Kremen Sarah
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- Le Hellard Stephanie
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- Leary Laura
- Lee Athena
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- Lee Virginia
- Lemaitre Hervé
- Lenahan Art
- Leonard Gabriel
- Lerner Alan
- Lethbridge Emma
- Lett Tristram A
- Leverenz James
- Levey Allan I
- Lewis Lindsay
- Lewis Lindsay B
- Li Shuo
- Liang Grace
- Lim Kelvin O
- Lin Honghuang
- Lin Michael
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- Linder Carly
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- Loeffler Markus
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- Martinot Jean-Luc
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- Mason Sara S
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- Melle Ingrid
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- Mesulam M Marcel
- Mesulam Marek-Marsel
- Meyer Javier Villanueva
- Meyer-Lindenberg Andreas
- Michie Patricia T
- Milaneschi Yuri
- Millenet Sabina
- Miller Bruce L
- Miller Delwyn D
- Miller Sarah
- Minton Mark
- Mintun Mark A
- Mintz Akiva
- Mintzer Jacobo
- Miranda Ruben
- Mirza-Schreiber Nazanin
- Mishra Aniket
- Mitsis Effie
- Mollenhauer Brit
- Monahan Nancy
- Montine Tom
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- Morey Rajendra A
- Morris Derek W
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- Mosley Thomas H
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- Mota Nina Roth
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- Mueller Bryon A
- Muglia Pierandrea
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- Muni Donna
- MĂŒhleisen Thomas W
- MĂŒller-Myhsok Bertram
- Najt Pablo
- Nakahara Soichiro
- Nam Ki Won
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- Neale Michael C
- Nees Frauke
- Neu Scott
- Nho Kwangsik
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- Nyberg Lars
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- Ogrocki Paula
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- Olichney John
- Oliver Angela
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- Opel Nils
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- Ostrowizki Suzanne
- Ott Brian R
- Ottmann Ruth
- Oyonumo Ntekim E
- Pacini Nathaniel
- Paillere Marie-Laure
- Painter Jodie N
- Panizzon Matthew S
- Pantelis Christos
- Papadopoulos Dimitri
- Parfitt Francine
- Pasternak Stephen
- Paul Steven
- Paus Tomas
- Paus TomĂĄĆĄ
- Pausova Zdenka
- Pausova Zdenka
- Pavese Nicola
- Pavlik Valory
- Pavlosky William
- Pawluczyk Sonia
- Pearlson Godfrey D
- Pearson John F
- Penninx Brenda W J H
- Pentilla Jani
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- Pitcher Toni L
- Pizzagalli Fabrizio
- Poewe Werner
- Poki-Walker Kim
- Polderman Tinca J C
- Poline Jean-Baptiste
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- Portillo Alicia
- Posthuma Danielle
- Potkin Steven
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- Preda Adrian
- Psaty Bruce M
- PĂŒtz Benno
- Quiceno Mary
- Quidé Yann
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- Quinlan Erin Burke
- Quinn Joseph
- Rachinsky Irina
- Radtke Rodney
- Ragothaman Anjanibhargavi
- Raichle Marc
- Rainka Michelle
- Raj Balebail Ashok
- Ranola Madelaine
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- Ratnakar Varun
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- Ravina Bernard
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- Reith Alastair D
- Relkin Norman
- Reppermund Simone
- Repple Jonathan
- Reynolds Brigid
- Richard GeneviĂšve
- Richard Irene
- Richer Louis
- Riedel Brandalyn C
- Rietschel Marcella
- Riordan Cheryl
- Risacher Shannon L
- Robbins Trevor
- Robert Gabriel
- Rocha Cristiane S
- Rodriguez Rosemarie
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- Rogalski Emily
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- Rudolph Alice
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- Sachdev Perminder S
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- Sadowsky Carl
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- Salloway Stephen
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- Venkov Heli
- Verhoef Ellen
- Vernooij Meike W
- Villena Teresa
- Villringer Arno
- Voyvodic James T
- Völker Uwe
- Völzke Henry
- Walter Henrik
- Walter Henrik
- Walter Sarah
- Walton Esther
- Wang Mingyuan
- Wang Yunpeng
- Ward Chad
- Wardlaw Joanna M
- Wardlaw Joanna M
- Weber Bernd
- Weinberger Daniel R
- Weiner Michael
- Weiner Michael W
- Weintraub Sandra
- Wen Wei
- Wen Wei
- Westlye Lars T
- Whelan Christopher D
- Whelan Robert
- Whelan Robert
- White Tonya
- Willeke Diana
- Williams Karen
- Williams Steve
- Wilson Renee
- Winkfield David
- Witbracht Megan
- Witt Stephanie H
- Witte A Veronica
- Wittfeld Katharina
- Wittfeld Katharina
- Wolf Christiane
- Wolfers Thomas
- Wolk David A
- Womack Kyle
- Wong Terence Z
- Woo Ellen
- Wright Margaret J
- Wright Margaret J
- Wu Chuang-Kuo
- Wu Jing Qin
- Wurster Isabel
- Xia Rui
- Yamamori Hidenaga
- Yanez Beatriz
- Yang Mia
- Yang Qiong
- Yang Qiong
- Yankey Jon
- Yasuda Clarissa L
- Yeh Randy
- Yesavage Jerome
- Zamrini Edward
- Zare Habil
- Zaremba Dario
- Zhang Zuo
- Zhou Juan
- Zhu Alyssa H
- Zimmerman Earl A
- Ziolkowski Jaimie
- Zsembik Leo C P
- Zwiers Marcel P
- Publication venue
- 'American Association for the Advancement of Science (AAAS)'
- Publication date
- 01/01/2020
- Field of study
The cerebral cortex underlies our complex cognitive capabilities, yet little is known about the specific genetic loci that influence human cortical structure. To identify genetic variants that affect cortical structure, we conducted a genome-wide association meta-analysis of brain magnetic resonance imaging data from 51,665 individuals. We analyzed the surface area and average thickness of the whole cortex and 34 regions with known functional specializations. We identified 199 significant loci and found significant enrichment for loci influencing total surface area within regulatory elements that are active during prenatal cortical development, supporting the radial unit hypothesis. Loci that affect regional surface area cluster near genes in Wnt signaling pathways, which influence progenitor expansion and areal identity. Variation in cortical structure is genetically correlated with cognitive function, Parkinson's disease, insomnia, depression, neuroticism, and attention deficit hyperactivity disorder
Measurement of the top quark forward-backward production asymmetry and the anomalous chromoelectric and chromomagnetic moments in pp collisions at âs = 13 TeV
- Author
- Aarrestad Thea Klaeboe
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdelalim Ahmed Ali
- Abdullin Salavat
- Abercrombie Daniel
- Abu Zeid Shimaa
- Acharya Himal
- Acosta Darin
- Acosta John Gabriel
- Adam Wolfgang
- Adams Mark Raymond
- Adams Todd
- Adzic Petar
- Afanasiev Serguei
- Agapitos Antonis
- Agarwal Garvita
- Aggleton Robin
- Agram Jean-Laurent
- Aguilar-Benitez Manuel
- Ahmad Ashfaq
- Ahmad Muhammad
- Ahmad Muhammad
- Ahuja Sudha
- Akbiyik Melike
- Akchurin Nural
- Akgun Bora
- Albajar Carmen
- Albergo Sebastiano
- Albert Andreas
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- Aleksandrov Aleksandar
- Alexander James
- Alhusseini Mohammad
- Alimena Juliette
- Allen Brandon
- Almond John
- Alvarez Gonzalez Barbara
- Alverson George
- Alves Gilvan
- Aly Reham
- Alyari Maral
- Amapane Nicola
- Ambrogi Federico
- Amendola Chiara
- Amin Nick
- Amsler Claude
- Anagnostou Georgios
- Anderson Dustin
- Andrea Jeremy
- Andreev Vladimir
- Andreev Yuri
- Andrews Michael Benjamin
- Androsov Konstantin
- Antchev Georgy
- Antunovic Zeljko
- Apanasevich Leonard
- Apollinari Giorgio
- Apresyan Artur
- Apyan Aram
- Araujo Mariana
- Arcaro Daniel
- Arcidiacono Roberta
- Arenton Michael Wayne
- Argiro Stefano
- Arneodo Michele
- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Asenov Patrick
- Askew Andrew
- Asmuss Paul
- Atakisi Ismail Okan
- Ather Mohsan Waseem
- Attikis Alexandros
- Auffray Etiennette
- Aushev Tagir
- Autermann Christian
- Auzinger Georg
- Avati Valentina
- Avery Paul
- Avila Carlos
- Awan Muhammad Imran Malik
- Ayala Edy
- Azarkin Maksim
- Azhgirey Igor
- Aziz Tariq
- Azzi Patrizia
- Azzurri Paolo
- Baarmand Marc M
- Babaev Anton
- Babounikau Illia
- Bacchetta Nicola
- Bachiller Irene
- Bachtis Michail
- Backhaus Malte
- Baden Drew
- Baechler Joachim
- Bagliesi Giuseppe
- Bahinipati Seema
- Baillon Paul
- Bainbridge Robert
- Bakas Georgios
- Bakhshiansohi Hamed
- Baldenegro Barrera Cristian
- Ball Austin
- Ban Yong
- Band Reyer
- Banerjee Sudeshna
- Banerjee Sunanda
- Bansal Sunil
- Barbagli Giuseppe
- Barberis Emanuela
- Bargassa Pedrame
- Baringer Philip
- Barker Anthony
- Barnes Virgil E
- Barney David
- Barnyakov Alexander
- Baron Owen
- Barria Patrizia
- Barrio Luna Mar
- Bartek Rachel
- Bartosik Nazar
- BartĂłk MĂĄrton
- Baselga Marta
- Baskakov Alexey
- Bastos Diogo
- Bat Ayse
- Battilana Carlo
- Baty Austin
- Bauerdick Lothar AT
- Baur Sebastian
- Bayshev Igor
- Bean Alice
- Beauceron Stephanie
- Beaudette Florian
- Beernaert Kelly
- Beghin Diego
- Behera Prafulla Kumar
- Behnke Olaf
- Behrens Ulf
- Bein Samuel
- Belchior Batista Das Chagas Ewerton
- Belforte Stefano
- Bell Ken W
- Bellan Riccardo
- Belloni Alberto
- Bellora Andrea
- Belyaev Alexander
- Belyaev Andrey
- Benaglia Andrea
- Benato Lisa
- Bencze Gyorgy
- Bendavid Joshua
- Benecke Anna
- Benelli Gabriele
- Beni Noemi
- Benitez Jose F
- Benussi Luigi
- Beretvas Andrew
- Bergauer Thomas
- Berger Pirmin
- Berger Thomas
- Beri Suman Bala
- BermĂșdez MartĂnez Armando
- Bernardes Cesar Augusto
- Bernet Colin
- Berry Douglas
- Berryhill Jeffrey
- Bertacchi Valerio
- Besancon Marc
- Beschi Andrea
- Betts Russell Richard
- Bhal Eshwen
- Bhandari Rohan
- Bhardwaj Ashutosh
- Bhardwaj Rishika
- Bharti Monika
- Bhat Muzamil Ahmad
- Bhat Pushpalatha C
- Bhatnagar Vipin
- Bhattacharya Rajarshi
- Bhattacharya Saptaparna
- Bhattacharya Satyaki
- Bhattacharya Soham
- Bhawandeep Bhawandeep
- Bheesette Srinidhi
- Bhowmik Debabrata
- Bhowmik Sandeep
- Bhyun Ji Hwan
- Bi Ran
- Bialkowska Helena
- Bianchini Lorenzo
- Bianco Michele
- Bianco Stefano
- Biasini Maurizio
- Biino Cristina
- Bilei Gian Mario
- Bilin Bugra
- Bilki Burak
- Bin Anuar Afiq Aizuddin
- Bisello Dario
- Bitioukov Sergei
- Black Kevin
- Blekman Freya
- Blinov Vladimir
- Bloch Daniel
- Bloch Philippe
- Bloom Kenneth
- Bluj Michal
- Blumenfeld Barry
- Boccali Tommaso
- Bocci Andrea
- Bodek Arie
- Boimska Bozena
- Boletti Alessio
- Bologna Simone
- Bols Emil SĂžrensen
- Bonacorsi Daniele
- Bonchev Miroslav
- Bondu Olivier
- Boos Edouard
- Boran Fatma
- Borchsh Vladislav
- Boren Samuel
- Borg Johan
- Borgonovi Lisa
- Bornheim Adolf
- Borras Kerstin
- Bortignon Pierluigi
- Bose Tulika
- Bossini Edoardo
- Botta Cristina
- Botta Valeria
- Boudoul Gaelle
- Bouhali Othmane
- Bourgatte Guillaume
- Bourilkov Dimitri
- Bozzo Marco
- Bragagnolo Alberto
- Braghieri Alessandro
- Braibant-Giacomelli Sylvie
- Brainerd Christopher
- Brandt Stephanie
- Branson James G
- Bravo Cameron
- Breedon Richard
- Breeze Shane
- Brew Christopher
- Brigljevic Vuko
- Brinkerhoff Andrew
- Brivio Francesco
- Brochero Cifuentes Javier Andres
- Brom Jean-Marie
- Brondolin Erica
- Brooke James John
- Brown Robert M
- Bruno Giacomo
- Brzhechko Danyyl
- Bucci Rachael
- Buccilli Andrew
- Buchanan James
- Buchmuller Oliver
- Bueghly James
- Bundock Aaron
- Bunichev Viacheslav
- Bunin Pavel
- Bunkowski Karol
- Buontempo Salvatore
- Burkett Kevin
- Burkle Bjorn
- Burns Douglas
- Burt Kira
- Busson Philippe
- Busza Wit
- Butler Joel Nathan
- Butler Philip H
- Butz Erik
- Bylinkin Alexander
- Bylsma Ben
- Byszuk Adrian
- Cabrera Andrés
- Cabrillo Iban Jose
- Cadamuro Luca
- Caillol CĂ©cile
- Cakir Altan
- Calabria Cesare
- Calderon De La Barca Sanchez Manuel
- Calderon Alicia
- Cali Ivan Amos
- Call Kenneth
- Calligaris Luigi
- Camen Camille
- Caminada Lea
- Campagnari Claudio
- Campanini Renato
- Campbell Alan
- Camporesi Tiziano
- Candelise Vieri
- Canelli Maria Florencia
- Canepa Anadi
- Cankocak Kerem
- Capiluppi Paolo
- Cappati Alessandra
- Caputo Claudio
- Caratelli Alessandro
- Caraway Bryan
- Cardini Andrea
- Carle Aurélien
- Carlin Roberto
- Carlsmith Duncan
- Carrera Jarrin Edgar
- Carrillo Montoya Camilo Andres
- Carrillo Moreno Salvador
- Cartiglia Nicolo
- Carvalho Antunes De Oliveira Alexandra
- Carvalho Wagner
- Casarsa Massimo
- Caspart René
- Cassese Antonio
- Castaldi Rino
- Castaneda Hernandez Alfredo
- Castilla-Valdez Heriberto
- Castro Andrea
- Cavallari Francesca
- Cavallo Francesca Romana
- Cavallo Nicola
- Cavanaugh Richard
- Ceccarelli Rudy
- Celik Ali
- Cepeda Maria
- Cerati Giuseppe Benedetto
- Cerci Salim
- Cerminara Gianluca
- Cerrada Marcos
- Cerri Olmo
- Chabert Eric Christian
- Chahal Gurpreet Singh
- Chang Paoti
- Chang Philip
- Chanon Nicolas
- Chao Yuan
- Chapon Emilien
- Charlot Claude
- Chatterjee Rajdeep Mohan
- Chatterjee Suman
- Chauhan Shubhanshu
- Chauhan Sushil
- Chawla Ridhi
- Chazin Quero Barbara
- Checchia Paolo
- Chen Geng
- Chen Guo-Ming
- Chen He-Sheng
- Chen Kai-Feng
- Chen Mingshui
- Chen Po-Hsun
- Chen Xuan
- Chen Yuan
- Chenarani Shirin
- Cheng Tongguang
- Cheng Yangyang
- Cherepanov Vladimir
- Chernyavskaya Nadezda
- Chertok Maxwell
- Cheung Harry
- Chhibra Simranjit Singh
- Chiarito Brandon
- Chierici Roberto
- Chinellato Jose
- Chistov Ruslan
- Chlebana Frank
- Cho Sungwoong
- Choi Junho
- Choi Suyong
- Choi Young-Il
- Chou John Paul
- Choudhary Brajesh C
- Choudhury Somnath
- Chtchipounov Leonid
- Chu Jennifer
- Chudasama Ruchi
- Chwalek Thorsten
- Ciangottini Diego
- Ciocca Claudia
- Ciocci Maria Agnese
- Cipriani Marco
- Ciriolo Vincenzo
- Cirkovic Predrag
- Citron Matthew
- Cittolin Sergio
- Ciulli Vitaliano
- Civinini Carlo
- Claes Daniel R
- Clare Robert
- Clement Emyr
- Clerbaux Barbara
- CMS Collaboration
- Cockerill David JA
- Cocoros Alice
- Codispoti Giuseppe
- Coelho Eduardo
- Colaleo Anna
- Cole Joanne
- Colino Nicanor
- Collard Caroline
- Colling David
- Cometti Simona
- Connor Patrick
- Consuegra RodrĂguez Sandra
- Contardo Didier
- Conte Eric
- Contreras-Campana Christian
- Conway John
- Conway Rylan
- Cooper Seth
- Cooperstein Stephane
- Cornelis Tom
- Correia Silva Gilson
- Cossutti Fabio
- Costa Marco
- Costa Salvatore
- Coubez Xavier
- Couderc Fabrice
- Coughlan John A
- Cousins Robert
- Covarelli Roberto
- Cox Bradley
- Cox Peter Timothy
- Creanza Donato
- Cremonesi Matteo
- Cristella Leonardo
- Csanad Mate
- Csorgo Tamas Ferenc
- Cucciati Giacomo
- Cuevas Javier
- Cuffiani Marco
- Cumalat John Perry
- Cummings Grace
- Cussans David
- Cutts David
- Czellar Sandor
- D'Alessandro Raffaello
- D'Alfonso Mariarosaria
- D'Enterria David
- D'Hondt Jorgen
- Da Rold Alessandro
- Da Silveira Gustavo Gil
- Dabrowski Anne
- Daci Nadir
- Dalchenko Mykhailo
- Dallavalle Gaetano-Marco
- Damarseckin Serdal
- Damgov Jordan
- Danilov Mikhail
- Danilov Vladyslav
- Daponte Vincenzo
- Darwish Mohamed Rashad
- Das Pallabi
- Das Souvik
- Dasgupta Abhigyan
- Daskalakis Georgios
- Dasu Sridhara
- Datta Abhisek
- Dauncey Paul
- David Tinoco Mendes Andre
- David Pieter
- Davies Gavin
- Davignon Olivier
- de Barbaro Pawel
- De Boer Wim
- De Bruyn Isabelle
- De Castro Manzano Pablo
- De Clercq Jarne
- De Cosa Annapaola
- De Filippis Nicola
- De Guio Federico
- De Iorio Agostino
- De Jesus Damiao Dilson
- De La Cruz Begona
- De La Cruz-Burelo Eduard
- De Lentdecker Gilles
- De Mattia Marco
- De Moraes Gregores Eduardo
- De Oliveira Martins Carley
- De Palma Mauro
- De Roeck Albert
- De Souza Lemos Dener
- de TrocĂłniz Jorge F
- De Wit Adinda
- De Wolf Eddi A
- Deelen Nikkie
- Defranchis Matteo Maria
- Deile Mario
- Deiters Konrad
- Dejardin Marc
- Del Burgo Riccardo
- Del Re Daniele
- Delaere Christophe
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- Yusli Mohd Nizam
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- Zahid Sema
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- Zalewski Piotr
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- Zanetti Marco
- Zarubin Anatoli
- Zarucki Mateusz
- Zecchinelli Angelo Giacomo
- Zenaiev Oleksandr
- Zenz Seth Conrad
- Zeuner Wolfram Dietrich
- Zevi Della Porta Giovanni
- Zghiche Amina
- Zhang Aobo
- Zhang Fengwangdong
- Zhang Huaqiao
- Zhang Jingyu
- Zhang Sijing
- Zhang Wenyu
- Zhang Yi
- Zhang Zhicai
- Zhao Jingzhou
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- Zhu Ren-Yuan
- Zientek Margaret
- Zlebcik Radek
- Zobec Joze
- Zoi Irene
- Zolkapli Zukhaimira
- Zorbakir Ibrahim Soner
- Zorbilmez Caglar
- Zotto Pierluigi
- Zou David
- Zucchetta Alberto
- Zumerle Gianni
- Zuo Xunwu
- Zuolo Davide
- Ălvarez FernĂĄndez Adrian
- Ăzçelik Ăzlem
- Publication venue
- Publication date
- 01/01/2019
- Field of study
Abstract The parton-level top quark (t) forward-backward asymmetry and the anomalous chromoelectric (dÌ t) and chromomagnetic (ÎŒÌ t) moments have been measured using LHC pp collisions at a center-of-mass energy of 13 TeV, collected in the CMS detector in a data sample corresponding to an integrated luminosity of 35.9 fbâ1. The linearized variable AFB(1) is used to approximate the asymmetry. Candidate t t ÂŻ events decaying to a muon or electron and jets in final states with low and high Lorentz boosts are selected and reconstructed using a fit of the kinematic distributions of the decay products to those expected for t t ÂŻ final states. The values found for the parameters are AFB(1)=0.048â0.087+0.095(stat)â0.029+0.020(syst),ÎŒÌt=â0.024â0.009+0.013(stat)â0.011+0.016(syst), and a limit is placed on the magnitude of | dÌ t| < 0.03 at 95% confidence level. [Figure not available: see fulltext.
Measurement of b jet shapes in proton-proton collisions at root s=5.02 TeV
- Author
- Aarrestad Thea Klaeboe
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdullin Salavat
- Abercrombie Daniel
- Acharya Himal
- Acosta Darin
- Acosta John Gabriel
- Adam Wolfgang
- Adams Mark Raymond
- Adams Todd
- Adzic Petar
- Afanasiev Serguei
- Agapitos Antonis
- Agarwal Garvita
- Aggleton Robin
- Agram Jean-Laurent
- Aguilar-Benitez Manuel
- Ahmad Ashfaq
- Ahmad Muhammad
- Ahmad Muhammad
- Ahuja Sudha
- Akbiyik Melike
- Akchurin Nural
- Akgun Bora
- Albajar Carmen
- Albergo Sebastiano
- Albert Andreas
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- Aleksandrov Aleksandar
- Alexander James
- Alhusseini Mohammad
- Alimena Juliette
- Alison John
- Allen Brandon
- Almond John
- Alvarez Gonzalez Barbara
- Alverson George
- Alves Gilvan
- Aly Reham
- Alyari Maral
- Amapane Nicola
- Ambrogi Federico
- Amendola Chiara
- Amin Nick
- Amsler Claude
- Anagnostou Georgios
- Anderson Dustin
- Andrea Jeremy
- Andreev Vladimir
- Andreev Yuri
- Andrews Michael Benjamin
- Androsov Konstantin
- Antchev Georgy
- Antunovic Zeljko
- Apanasevich Leonard
- Apollinari Giorgio
- Apresyan Artur
- Apyan Aram
- Araujo Mariana
- Arcaro Daniel
- Arcidiacono Roberta
- Arenton Michael Wayne
- Argiro Stefano
- Arneodo Michele
- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Asenov Patrick
- Askew Andrew
- Asmuss Paul
- Atakisi Ismail Okan
- Ather Mohsan Waseem
- Attikis Alexandros
- Auffray Etiennette
- Aushev Tagir
- Autermann Christian
- Auzinger Georg
- Avati Valentina
- Avery Paul
- Avila Carlos
- Awan Muhammad Imran Malik
- Ayala Edy
- Azarkin Maksim
- Azhgirey Igor
- Aziz Tariq
- Azzi Patrizia
- Azzurri Paolo
- Baarmand Marc M
- Babaev Anton
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- Sirunyan Albert M
- Skinnari Louise
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- Smirnov Igor
- Smirnov Vitaly
- Smith Caleb
- Smith Geoffrey
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- Tonelli Manganote Edmilson José
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- Zobec Joze
- Zoi Irene
- Zolkapli Zukhaimira
- Zorbakir Ibrahim Soner
- Zorbilmez Caglar
- Zotto Pierluigi
- Zou David
- Zucchetta Alberto
- Zumerle Gianni
- Zuo Xunwu
- Zuolo Davide
- Ălvarez FernĂĄndez Adrian
- Ăzçelik Ăzlem
- Publication venue
- Publication date
- 01/01/2020
- Field of study
We present the first study of charged-hadron production associated with jets originating from b quarks in proton-proton collisions at a center-of-mass energy of 5.02 TeV. The data sample used in this study was collected with the CMS detector at the CERN LHC and corresponds to an integrated luminosity of 27.4 pb(-1). To characterize the jet substructure, the differential jet shapes, defined as the normalized transverse momentum distribution of charged hadrons as a function of angular distance from the jet axis, are measured for b jets. In addition to the jet shapes, the per-jet yields of charged particles associated with b jets are also quantified, again as a function of the angular distance with respect to the jet axis. Extracted jet shape and particle yield distributions for b jets are compared with results for inclusive jets, as well as with the predictions from the pythia and herwig++ event generators.Peer reviewe
Measurement of the azimuthal anisotropy of Y(1S) and Y(2S) mesons in PbPb collisions at root s(NN)=5.02 TeV
- Author
- Aarrestad Thea Klaeboe
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdullin Salavat
- Abercrombie Daniel
- Acharya Himal
- Acosta Darin
- Acosta John Gabriel
- Adam Wolfgang
- Adams Mark Raymond
- Adams Todd
- Adzic Petar
- Afanasiev Serguei
- Agapitos Antonis
- Agarwal Garvita
- Aggleton Robin
- Agram Jean-Laurent
- Aguilar-Benitez Manuel
- Ahmad Ashfaq
- Ahmad Muhammad
- Ahmad Muhammad
- Ahuja Sudha
- Akbiyik Melike
- Akchurin Nural
- Akgun Bora
- Albajar Carmen
- Albergo Sebastiano
- Albert Andreas
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- Aleksandrov Aleksandar
- Alexander James
- Alhusseini Mohammad
- Alimena Juliette
- Alison John
- Allen Brandon
- Almond John
- Alvarez Gonzalez Barbara
- Alverson George
- Alves Gilvan
- Aly Reham
- Alyari Maral
- Amapane Nicola
- Ambrogi Federico
- Amendola Chiara
- Amin Nick
- Amsler Claude
- Anagnostou Georgios
- Anderson Dustin
- Andrea Jeremy
- Andreev Vladimir
- Andreev Yuri
- Andrews Michael Benjamin
- Androsov Konstantin
- Antchev Georgy
- Antunovic Zeljko
- Apanasevich Leonard
- Apollinari Giorgio
- Apresyan Artur
- Apyan Aram
- Araujo Mariana
- Arcaro Daniel
- Arcidiacono Roberta
- Arenton Michael Wayne
- Argiro Stefano
- Arneodo Michele
- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Asenov Patrick
- Askew Andrew
- Asmuss Paul
- Atakisi Ismail Okan
- Ather Mohsan Waseem
- Attikis Alexandros
- Auffray Etiennette
- Aushev Tagir
- Autermann Christian
- Auzinger Georg
- Avati Valentina
- Avery Paul
- Avila Carlos
- Awan Muhammad Imran Malik
- Ayala Edy
- Azarkin Maksim
- Azhgirey Igor
- Aziz Tariq
- Azzi Patrizia
- Azzurri Paolo
- Baarmand Marc M
- Babaev Anton
- Babounikau Illia
- Bacchetta Nicola
- Bachiller Irene
- Bachtis Michail
- Backhaus Malte
- Baden Drew
- Baechler Joachim
- Bagliesi Giuseppe
- Bahinipati Seema
- Baillon Paul
- Bainbridge Robert
- Bak Gyeonghwan
- Bakas Georgios
- Bakhshiansohi Hamed
- Baldenegro Barrera Cristian
- Ball Austin
- Ban Yong
- Band Reyer
- Banerjee Sudeshna
- Banerjee Sunanda
- Bansal Sunil
- Barbagli Giuseppe
- Barberis Emanuela
- Bargassa Pedrame
- Baringer Philip
- Barker Anthony
- Barnes Virgil E
- Barney David
- Barnyakov Alexander
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- Bartek Rachel
- Bartosik Nazar
- BartĂłk MĂĄrton
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- Behera Subash Chandra
- Behnke Olaf
- Behrens Ulf
- Bein Samuel
- Belchior Batista Das Chagas Ewerton
- Belforte Stefano
- Bell Ken W
- Bellan Riccardo
- Belloni Alberto
- Bellora Andrea
- Belyaev Alexander
- Belyaev Andrey
- Benaglia Andrea
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- Bencze Gyorgy
- Bendavid Joshua
- Benecke Anna
- Benelli Gabriele
- Beni Noemi
- Benitez Jose F
- Benussi Luigi
- Beretvas Andrew
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- Berger Pirmin
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- Bhardwaj Ashutosh
- Bhardwaj Rishika
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- Bhat Muzamil Ahmad
- Bhat Pushpalatha C
- Bhatnagar Vipin
- Bhattacharya Rajarshi
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- Bhattacharya Soham
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- Choudhury Somnath
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- Chu Jennifer
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- He He
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- Jindariani Sergo
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- Johnson Marvin
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- Jones Matthew
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- Joyce Matthew
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- Kaadze Ketino
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- Sirunyan Albert M
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- Smith Geoffrey
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- Yumiceva Francisco
- Yusli Mohd Nizam
- Zabi Alexandre
- Zacharopoulou Anna
- Zahid Sema
- Zaleski Shawn
- Zalewski Piotr
- Zanetti Anna
- Zanetti Marco
- Zarubin Anatoli
- Zarucki Mateusz
- Zecchinelli Angelo Giacomo
- Zenaiev Oleksandr
- Zenz Seth Conrad
- Zeuner Wolfram Dietrich
- Zevi Della Porta Giovanni
- Zghiche Amina
- Zhang Aobo
- Zhang Fengwangdong
- Zhang Huaqiao
- Zhang Jingyu
- Zhang Sijing
- Zhang Wenyu
- Zhang Yi
- Zhang Zhicai
- Zhao Jingzhou
- Zhokin Alexander
- Zhu De Hua
- Zhu Ren-Yuan
- Zientek Margaret
- Zlebcik Radek
- Zobec Joze
- Zoi Irene
- Zolkapli Zukhaimira
- Zorbakir Ibrahim Soner
- Zorbilmez Caglar
- Zotto Pierluigi
- Zou David
- Zucchetta Alberto
- Zumerle Gianni
- Zuo Xunwu
- Zuolo Davide
- Ălvarez FernĂĄndez Adrian
- Ăzçelik Ăzlem
- Publication venue
- Publication date
- 01/01/2020
- Field of study
The second-order Fourier coefficients (v(2)) characterizing the azimuthal distributions of Y(1S) and Y(2S) mesons produced in PbPb collisions at root s(NN) = 5.02 TeV are studied. The Y mesons are reconstructed in their dimuon decay channel, as measured by the CMS detector. The collected data set corresponds to an integrated luminosity of 1.7 nb(-1). The scalar product method is used to extract the v2 coefficients of the azimuthal distributions. Results are reported for the rapidity range vertical bar y vertical bar < 2.4, in the transverse momentum interval 0 < pT < 50 GeV/c, and in three centrality ranges of 10-30%, 30-50% and 50-90%. In contrast to the J/psi mesons, the measured v(2) values for the Y mesons are found to be consistent with zero. (C) 2021 The Author(s). Published by Elsevier B.V.Peer reviewe
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