15 research outputs found
Meta‐Analysis of Genome‐wide Linkage Studies in BMI and Obesity
- Author
- Abelson P.
- Adebowale A. Adeyemo
- Adeyemo A.
- Ahmed H. Kissebah
- Amy Luke
- Anthony G. Comuzzie
- Arya R.
- Arya R.
- Atwood L. D.
- Aubert R.
- Bailey-Wilson J. E.
- Barsh G. S.
- Beck S. R.
- Bell C. G.
- Bell C. G.
- Benedetta D. Chiodini
- Bray G. A.
- Catherine L. Saunders
- Cathryn M. Lewis
- Chagnon Y. C.
- Chen W.
- Cheng R.
- Chiodini B. D.
- Cisca Wijmenga
- Collier D. A.
- Comuzzie A. G.
- Daley D.
- David A.Collier
- Delplanque J.
- Deng H. W.
- Dina C.
- Drewnowski A.
- Feitosa M. F.
- Fisher S.
- Frayling T. M.
- Geller F.
- Gerald S. Berenson
- Hager J.
- Hanson R. L.
- Heather Stringham
- Heijmans B. T.
- Herbert A.
- Hong-Wen Deng
- Hsu F. C.
- Hsueh W. C.
- Ingrid B. Borecki
- Iwasaki N.
- Johannes Hebebrand
- John Blangero
- Johnson L.
- Kissebah A. H.
- Lander E.
- Lee J. H.
- Leena Peltonen
- Leibowitz S. F.
- Levinson D. F.
- Lewis C. M.
- Lewis C. M.
- Li W. D.
- Li X.
- Lindsay R. S.
- Lisa J. Martin
- Liu X. Q.
- Lyle J. Palmer
- Mariza de Andrade
- Markus Perola
- Mary F. Feitosa
- Matthew Nash
- Meyre D.
- Michael Boehnke
- Michael P. Stern
- Miina Öhman
- Mitchell B. D.
- Moslehi R.
- Nash M. W.
- Ohman M.
- Pak Sham
- Palmer L. J.
- Palmer L. J.
- Pardi F.
- Patricia Huezo-Dias
- Perola M.
- Philippe Froguel
- R. Arlen Price
- Ravindranath Duggirala
- Rector Arya
- Robert L. Hanson
- Saar K.
- Sathanur R. Srinivasan
- Schousboe K.
- Scuteri A.
- Silander K.
- Snyder E. E.
- Stephen Turner
- Steven Stone
- Stoll M.
- Stone S.
- Susan Redline
- Turner S. T.
- van Tilburg J. H.
- Victor Abkevich
- Watanabe R. M.
- Wei Chen
- Weidong Li
- Wilson A. F.
- Wise L. H.
- Wu X. D.
- Yoo Y. J.
- Yvon C. Chagnon
- Zintzaras E.
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2007
- Field of study
Objective: The objective was to provide an overall assessment of genetic linkage data of BMI and BMI‐defined obesity using a nonparametric genome scan meta‐analysis. Research Methods and Procedures: We identified 37 published studies containing data on over 31,000 individuals from more than >10,000 families and obtained genome‐wide logarithm of the odds (LOD) scores, non‐parametric linkage (NPL) scores, or maximum likelihood scores (MLS). BMI was analyzed in a pooled set of all studies, as a subgroup of 10 studies that used BMI‐defined obesity, and for subgroups ascertained through type 2 diabetes, hypertension, or subjects of European ancestry. Results: Bins at chromosome 13q13.2‐ q33.1, 12q23‐q24.3 achieved suggestive evidence of linkage to BMI in the pooled analysis and samples ascertained for hypertension. Nominal evidence of linkage to these regions and suggestive evidence for 11q13.3‐22.3 were also observed for BMI‐defined obesity. The FTO obesity gene locus at 16q12.2 also showed nominal evidence for linkage. However, overall distribution of summed rank p values <0.05 is not different from that expected by chance. The strongest evidence was obtained in the families ascertained for hypertension at 9q31.1‐qter and 12p11.21‐q23 (p < 0.01). Conclusion: Despite having substantial statistical power, we did not unequivocally implicate specific loci for BMI or obesity. This may be because genes influencing adiposity are of very small effect, with substantial genetic heterogeneity and variable dependence on environmental factors. However, the observation that the FTO gene maps to one of the highest ranking bins for obesity is interesting and, while not a validation of this approach, indicates that other potential loci identified in this study should be investigated further.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/93663/1/oby.2007.269.pd
Finishing the euchromatic sequence of the human genome
- Author
- . Haifeng
- . Magner
- . Yin
- Abbott Scott
- Abbott-Ozersky Amanda
- Abdellah Zahra
- Abouelleil Amr
- Abrajano Anne
- Adachi Tamami
- Adam Catherine
- Adams Charles Q.
- Adamson Aaron
- Adekoya Emmanuel
- Adio-Oduola Babajide
- Aerts Andrea
- Aggarwal Arun
- Ahmadi Alireza
- Ahmed Shahana
- Aimable Matthew
- Ainscough Rachael
- Ait-Zahra Mostafa
- Aizu Tomoyuki
- Alcivare Dana
- Alegria Michelle
- Ali Alla
- Ali Johar
- Allegria-hartmann Michelle
- Alleman Jennifer
- Allen Carlana C.
- Allen Heather
- Allen Nicole R.
- Allen Susan
- Allen Thaddeus
- Almeida Jeff
- Almond Claire
- Alsbrooks Stephen L.
- Altherr Michael R.
- Amaratunge Harshinie C.
- Ambler Andrew
- Ambrose Karen
- Ambrose Kerrie
- Amemiya Chris
- Amico-Keller Gina
- Amin Amita G.
- Anderson Mechele
- Anderson Scott
- Anderson Scott
- Andora Janice
- Andredesz Carol
- Andrew Robert
- Andrews Dan
- Andrews Daniel
- Andrews Neil
- Andrews Stephanie
- Andriese Tim
- Anthouard Véronique
- Antonarakis Stylianos E.
- Anyalebechi Vivian
- Aoki Norie
- Apostolou Sinoula
- Apweiler Eva
- Arachchi Harindra
- Arai Rie
- Arbery Hazel
- Arcaina Marlon
- Arcaina Terisita
- Archer Beth
- Arellano Andre
- Arellano-Jones Perry
- Armbruster Jeff
- Armstrong Jon
- Arredondo Dilrukshi P.
- Arredondo Heather Hope
- Artiguenave François
- Asakawa Shuichi
- Asakawa Teruyo
- Ash Gareth
- Ashcroft Kevin
- Ashurst Jennifer
- Ashwell Robert
- Ashworth Linda K.
- Aslanidis Cara
- Asomugha Chinwe O.
- Asuncion Lawreen
- Atkin Deborah
- Atkinson Andrea
- Atkinson Barry
- Attix Cristina
- Attwood John
- Aubin Keith
- Auger Katherine
- Austin Shannon Michelle
- Avila Aaron
- Avis Terry
- Ayele Mulu
- Babayan Primo
- Babbage Anne
- Babbage Sarah
- Bach Phil
- Bachatsang Pasang
- Bacon Joanne
- Badri Hummy
- Baertsch Robert
- Bagguley Claire
- Bailey Jonathan
- Bajorek Eva
- Baker Andrew
- Baker Dan
- Baker M.
- Baker Richard
- Bakis Michele
- Baldwin Jennifer
- Banda Michael
- Banerjee Ruby
- Bao Jingyue
- Bao Qiyu
- Bao Weidong
- Bao Weidong
- Baptiste Pertrice
- Barbaria Joseph A.
- Barbe Valérie
- Bardill Simon
- Barker Daniel
- Barker Darren
- Barker Gary
- Barlow Karen
- Baron Laurent
- Barrett Anika
- Bartlett Rebecca
- Basham Victoria
- Bashman David
- Basu Suba
- Bateman Alex
- Bates Karen
- Battles John
- Batzer Mark
- Baumgart Cornelia
- Baumohl Jason
- Baynes Caroline
- Bayul Tashi
- Beall Keith
- Beard Lisa
- Beard Susan
- Beare David
- Beasley Alastair
- Beasley Helen
- Beasley Oliver
- Beaucham Leslie
- Beaudet Arthur
- Beck Alfred
- Beck Stephen
- Becker Michael
- Bell Emma
- Bell George I.
- Bellard Terell M.
- Bellerby Damian
- Bellerby Tristram
- Belter Edward A., Jr.
- Bemrose Richard
- Benard Michael Anthony
- BenKahla Alia
- Benke J
- Benner William
- Bennett James
- Bensasson Douda
- Bentley Andrew
- Bentley Dan
- Bentley David
- Berardinis Véronique de
- Bercovitz John
- Berghoff Amy
- Bergmann Anne
- Berkowicz Nicolas
- Berks Mary
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- Bethel Graeme
- Beugelsdijk Tony J.
- Bhakta Rita
- Bhuchar Venita
- Bi Shihua
- Bian Xuemeng
- Bieri Tamberlyn
- Bimage Kesha E.
- Bird Christine
- Birditt Brian
- Birney Ewan
- Birney Ewan
- Birren Bruce
- Bissell Helen
- Biswalo Kaneza
- Bituin Aleksandr
- Black Stacey
- Blackburne-Maze Suzanne
- Blair Jessica Anne
- Blakey Sarah
- Blanks Tia
- Blasiar Darin
- Blazej Robert
- Blitshsteyn Berta
- Blomstrom David B.
- Bloom Scott
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- Blumer Heather
- Blye Jason
- Blyth Peter R.
- Blöcker Helmut
- Boatright Elizabeth
- Boehm John
- Boen Juanan
- Boguslavskiy Leonid
- Bolton Christel
- Bolund Lars
- Bondoc Marnel
- Bonfield James
- Bonnett Ralph
- Bonnin David
- Border Richard
- Borowsky Mark
- Borzym Katja
- Boukhgalter Boris
- Bowen Eric
- Bradley Amanda
- Bradshaw-Cordum Holly
- Brady Nicola
- Brandriff Brigitte F.
- Brannon Wade
- Branscomb Elbert
- Bray Jason
- Bray-Allen Sarah
- Brettin Thomas
- Bridgeman Anne
- Bridgers Michael
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- Brokstein Peter
- Brook Jonathan
- Brooking Shane
- Brottier Philippe
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- Budd Claire
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- Chen Jianlong
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- Chen Jin
- Chen Junbao
- Chen Lihong
- Chen Lixia
- Chen Ray
- Chen Shu
- Chen Tong
- Chen Xiaoyun
- Chen Xinyi
- Chen Yanjiong
- Chen Yiyu
- Chen Zhu
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- Cheng Zhihua
- Chertkov Olga
- Cheshatsang Yama
- Chi Cheng
- Chi Han C.
- Chillingworth Neil
- Chin Sylvia
- Chinn Corey
- Chinwalla Asif
- Chissoe Stephanie
- Chiu Sally
- Chothia Tom
- Christensen Mari
- Christopoulos Constantine
- Chu Joseph
- Chui Connie
- Chung A
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- Citroen Mieke
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- Clarke Betty
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- Clarke Laura
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- Clee Chris
- Clegg Shelia
- Clerc Blankenburg Kerstin Petra
- Cleveland David
- Clifford Karen
- Clifton Sandra W.
- Coates Julia
- Cobley Victoria
- Cockrell Raynard
- Coffey Alison
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- Coggill Penelope
- Cohn Judith D.
- Colayco Rick
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- Collings Simon
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- Colman Louise
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- Comstock Robin
- Cong Bin
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- Connolly Anthony
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- Conroy Donald
- Considine Tony
- Constance Doug
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- Cooke Patrick
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- Copsey Teresa
- Corby Nicole
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- Davis Jayne
- Davis John
- Davis Matthew
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- Dawoe Tenzin
- Dawson Elisabeth
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- Fernandez Sonia
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- Harding Adam
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- Harley Joanne
- Harper David
- Harper Georgina
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- Harrison Charlene-Lou
- Harrison Elliot
- Harrison Ruth
- Hart Elizabeth
- Hasegawa Tomoko
- Hashimoto Etsuko
- Hashimoto Wakako
- Hassan Daniel
- Hatcher Beath
- Hattori Masahira
- Haugen Eric
- Haussler David
- Havlak Paul
- Hawes Alicia C.
- Hawkins Ebere Sylvia Onyirioha
- Hawkins Natalie
- Hawkins Trevor
- Hawley Kellie
- Haydu Lauren
- Hayes Kerry
- He Fengying
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- Heaford Andrew
- Heath Paul
- Heathcott Rosemary
- Heilig Roland
- Heiner Cheryl
- Heinze Ivonne
- Heitmann Katja
- Helfenbein Keven
- Heller Andrew
- Hellsten Uffe
- Hembry Cathy
- Henderson Carl
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- Hendrix David
- Hennig Steffen
- Henning Karla
- Hepa Victor
- Herd Tim
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- Hernandez Judith
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- Heyen Joshua
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- Hillier LaDeana
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- Hitchens Matthew Edward
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- Holden Jane
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- Hollaway Mara
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- Hopewell Lucy
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- Hornsby Tony
- Horsley Sharon
- Horton Roger
- Hosage-Norman Catherine
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- Howard Philip
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- Howden Philip
- Howe Kevin
- Howell Gareth
- Howell Latoya Lynette
- Howells Sally Lucinda
- Hsu Fan
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- Hu Songnian
- Huang Fang
- Huang Guyang
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- Huang Wei
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- Hubbard Timothy
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- Huckle Elizabeth
- Hue Heather
- Hughes Jaime
- Hughes Jennifer
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- Hunt Paul
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- Hunter Rov, II
- Hupman Matt
- Huynh Sandy
- Hyde David
- Hynds Christopher
- Idlebird Devincent G.
- Iliev Ilian
- Imbro Paula
- Imo Kelvin C.
- Inacio Nicole
- Inagaki Naomi
- Ince Michael
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- Isak Amber
- Isherwood Judith
- Ishibashi Akiko
- Ishikawa Sabine K.
- Ishizaki Hinako
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- Itoh Takehiko
- Iwakawa Shinobu
- Iwatate Mariko
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- Izatt Janet
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- Jackson Terri
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- Jaeger Sara
- Jaffe David B.
- Jahn Niels
- Jaklevic Joseph
- Jaklevic Michael
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- Jekosch Kerstin
- Jenkins Lee
- Jett Jamie
- Jewett Phillip E.
- Jia Jia
- Jia Jia
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- Jimenez Alberto
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- Kosiura Anna
- Kou Zhaohui
- Kovar Christie L.
- Krawczyk Marie-Claude
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- Kremmidiotis Gabriel
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- Kronmiller Brent
- Kruchowski Scott S.
- Kube Michael
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- Lamerdin Jane E.
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- Landers Tom
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- Lewis Doreen
- Lewis Ernest K.
- Lewis Keith
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- Li Changfeng
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- Lindblad-Toh Kerstin
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- Lopez Frederick
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- Lorensuhewa Lorna M.
- Lou Yunian
- Loulseged Hermela
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- Lovell Jamie
- Lovett Demetria A.
- Lowenstein Michael G.
- Lowry Stephen
- Lozado Ryan J.
- Lu Lingfeng
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- Lu Yongxiang
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- Lu Yue
- Lucas Robert
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- Lucier Raymond L.
- Ludeman Thom
- Lui Annie
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- MacLean Christine
- Madabhushi Ramki
- Madu Renita C.
- Maeda Hideto
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- Maheshwari Manjula
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- Maltbie Mary I.
- Mangum Brian
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- Manohar Chitra
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- Mardis Elaine R.
- Mareth David
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- Marinelli Lisa
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- Marquis-Homeyer Catherine
- Marr Thomas G.
- Marra Marco
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- Matthews Lucy
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- Mauceli Evan
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- McLeod Michael P.
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- McMurray Amanda
- McMurray Des
- McMurray Kimberly
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- McPherson John
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- Meidi Patrick
- Meier Elke
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- Mercado Iracema C.
- Mercer Simon
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- Mesirov Jill P.
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- Minja Emmanuel
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- Mullenger Ian
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- Mungall Andy
- Munidasa Mala
- Munk A. Christine
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- Munson Glen
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- Murayama Yuji
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- Nagamine Kentaro
- Nagao Syunsuke
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- Nair Seema R.
- Naka Maho
- Nakagawa Masayo
- Nakagawa Saori
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- Nakato Eriko
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- Nankervis Colin E.
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- Naylor Jerome
- Nazareth Lynne V.
- Neal Dearl D.
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- Nelson Catherine
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- Nelson Deborah A.
- Nelson Joanne
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- Ng Bee
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- Nguyen Natalie M.
- Nguyen Ngoc Bich
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- Novik Karen
- Nowlin Larry
- Nusbaum Chad
- Nwaokelemeh Ogechi O.
- Nwokenkwo Stanley
- O\u27Donnell Paula
- O\u27Donovan Daniel
- O\u27Leary Sinead
- O\u27Loughlin Jennifer
- O\u27Neill Keith
- Obayashi Izumi
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- Ohtsubo Masafumi
- Oinn Tom
- Okoawo Ose
- Okui Michiyo
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- Okwuonu Geoffrey O.
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- Olivas Jason
- Oliver Hayley
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- Olson Maynard V.
- Omotosho Bamidele
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- Oomori Nobuhiro
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- Oragunye Njideka
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- Ovcharenko Ivan
- Overton-Larty Emma
- Oviedo Rodolfo J.
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- Ozawa Ritsuko
- Ozersky Philip
- Pace Araceli C.
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- Pan Jiaofeng
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- Parkin Christopher
- Parkin Kim
- Parks Kenya L.
- Parry-Brown Ginny
- Parson-Quintana Beverly
- Pasternak Shiran
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- Patel Vishal V.
- Patrick James
- Paul Heidie A.
- Paul Shelia
- Paulson Edward
- Payton Brett A.
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- Pearman Charlene
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- Peng Vivian
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- Peng Yi
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- Pennacchio Len A.
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- Perez Agapito
- Perez Lesette M.
- Perito Andrew
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- Perrin William
- Pesavento Brad
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- Polman Jos
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- Porter Keith
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- Poundstone Pat
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- Prathalingham Radhika
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- Qin Xiang
- Quail Michael
- Quan Glenda
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- Quiles Miyo M.
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- Quiroz Juana B.
- Qureshi Matloob
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- Radionenko Maxim
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- Riethman Harold
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- Sasaki Takashi
- Satpathy Suraj
- Saunders David
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- Saurin William
- Savery Glenford G.
- Sawada Nori
- Sawhill William W.
- Saxman Eric
- Scarpelli Claude
- Scharfe Maren
- Schatzkamer Kyriena L.
- Scherer Steven Edward
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- Siepel Adam C.
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- Sonnhammer Erik
- Sonnhammer Erik
- Sorelle Richard P.
- Sotheran Elizabeth
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- Stallings Raymond I.
- Stalvey Malinda
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- Su Xiaohu
- Subramanian Sandhya
- Subramanian Sandhya
- Sudbrak Ralf
- Sugnet Charles W.
- Sulston John
- Summers Leslie J.
- Sun Hui
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- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
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- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
PNAG-specific equine IgG1 mediates significantly greater opsonization and killing of Prescottella equi (formerly Rhodococcus equi) than does IgG4/7
- Author
- Achkar
- Angela I. Bordin
- Banks
- Bordin
- Bowles
- Casadevall
- Cauchard
- Chaffin
- Chaffin
- Cohen
- Cohen
- Colette Cywes-Bentley
- Collins
- Cywes-Bentley
- Edelson
- Gerald B. Pier
- Giguère
- Giguère
- Giguère
- Giguère
- Gonzalez-Iglesias
- Goodman
- Hamasur
- Hietala
- Hooper-McGrevy
- Ivanyi
- Joana N. Rocha
- Jocelyne M. Bray
- Johansson
- Lawrence J. Dangott
- Lewis
- Lopez
- Lu
- Martens
- McClelland
- McGuire
- Nelson
- Netski
- Noah D. Cohen
- Nordmann
- Nordmann
- Passwell
- Phumoonna
- Power
- Prados-Rosales
- Robert C. Alaniz
- Ross
- Sanz
- Sara D. Lawhon
- Shapiro
- Sidak
- Siggins
- Sugiura
- Suresh D. Pillai
- Takai
- Teitelbaum
- Vidarsson
- Waithaka Mwangi
- Yuan
- Zimmermann
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
Current and Potential Drugs for Treatment of Obesity
- Author
- AACE/ACE Obesity Task Force
- Abenhaim
- Abraham
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- Quaade
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- Ravussin
- Recasens
- Reitsma
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- Rosenberg
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- Rothwell
- Roy
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- Rushing
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- Russek
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- Ryan
- Ryan
- Rynearson
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- Sax
- Sayler
- Scalfi
- Scheen
- Scheffel
- Scheidegger
- Scheidegger
- Schteingart
- Schulman
- Schwartz
- Schwartz
- Schwartz
- Scottish Intercollegiate Guidelines Network
- Scoville
- Scrocchi
- Seagle
- Seaton
- Sedgwick
- Seidell
- Selikowitz
- Sensi
- Shape Up America and American Obesity Association1996 Guidance for Treatment of Adult Obesity
- Shapira
- Shargill
- Sharma
- Shetty
- Shimazu
- Shughrue
- Shutter
- Shutter
- Silva
- Silverstone
- Silverstone
- Silverstone
- Silverstone
- Silverstone
- Silverstone
- Silverstone
- Silverstone
- Silverstone
- Silverstone
- Simons
- Simson
- Singer
- Sjostrom
- Slama
- Smith
- Smith
- Smith
- Smith
- Smith
- Smith
- Smith
- Smith
- Smith
- Smith
- Snyder
- Snyder
- Snyder
- Snyder
- Sorhede
- Sours
- Sowers
- Spiess
- Spina
- Spitz
- Spring
- Sproule
- Stacher
- Stahl
- Stanko
- Stanko
- Stanko
- Stanley
- Stanley
- Stanley
- Stark
- Steel
- Stein
- Stein
- Stenzel-Poore
- Stephens
- Stewart
- Stewart
- Stirling
- Stoa-Birketvedt
- Stock
- Stock
- Stricker
- Strosberg
- Stunkard
- Stunkard
- Stunkard
- Stunkard
- Stunkard
- Stunkard
- Sullivan
- Sullivan
- Sundaresan
- Susulic
- Svec
- Swinburn
- Tauber-Lassen
- Taylor
- Tchernof
- Tecott
- Terada
- Terry
- Thom
- Thomas
- Thompson
- Thompson
- Thorpe
- Tian
- Tisdale
- Tonstad
- Tordoff
- Toubro
- Traherne
- Trent
- Truant
- Trulson
- Tsujii
- Tsujii
- Tsujii
- Tsujii
- Tsujii
- Tsujii
- Tuck
- Turtle
- Turton
- US Department of Health and Human Services
- US Department of Health and Human Services Drug Abuse Warning Network
- US Department of Health and Human Services Public Health Service Alcohol Drug Abuse and Mental Health Administration
- Usiskin
- Vaccarino
- Vaccarino
- Vagenakis
- Vague
- Valle-Jones
- Van Gaal
- Van Gaal
- VanderWeele
- VanItallie
- Veldhuis
- Vernace
- Vidal Puig
- Visser
- Voelkel
- Waal-Manning
- Wadden
- Wadden
- Wadden
- Wales
- Walker
- Wallace
- Waters
- Weber
- Weintraub
- Weintraub
- Weintraub
- Weintraub
- Weintraub
- Weintraub
- Weintraub
- Weintraub
- Weintraub
- Weintraub
- Weintraub
- Weintraub
- Weintraub
- Weintraub
- Weintraub
- Weir
- Weizman
- Welle
- Wellman
- Welsh
- Westphalen
- Weyer
- Wheeldon
- Wilbert
- Willey
- Willey
- William-Olsson
- Williams
- Williams
- Williams
- Williamson
- Williamson
- Wilson
- Wilson
- Wilson
- Wilson
- Wise
- Wolever
- Wood
- Woodhouse
- Woods
- Wurtman
- Wurtman
- Yamashita
- Yen
- Yoshida
- Yoshida
- Yoshida
- Yoshimatsu
- Young
- Zed
- Zhang
- Zhang
- Zhi
- Zhi
- Zhi
- Zhi
- Zumoff
- Zwiauer
- Publication venue
- 'The Endocrine Society'
- Publication date
- Field of study
“Socially Disruptive Actions … Have Become as Canadian as Maple Syrup”: Civil Disobedience in Canada, 1960–2012
- Author
- Alfred Gerald R
- Belanger Yale D
- Berman Tzeporah
- Bray Matt
- Byers R.B
- Campbell Lara
- Carter April
- Clément Dominique
- Douville Bruce
- Dunphy Catherine
- Gagnon Georgette
- Harris Paul.
- Hodgins Bruce W
- Johnstone Rachael
- King Mary E
- Levine Marc V
- Leyton-Brown David
- MacGuigan Mark R
- MacMillan C. Michael
- Meyer David S
- Miller J.R
- Morton F.L
- Owram Doug
- O’Connor Ryan
- Palmer Bryan D.
- Perry Lewis
- Pertusati Linda
- Power Paul F
- Quill Lawrence
- Ramos Howard
- Rawls John
- Sharp Gene
- Stettner Shannon
- Swain Harry
- Tatalovich Raymond
- Tindall D.B.
- Weber David R.
- Wiseman Nelson
- Woodcock George
- York Geoffrey
- Yorston John
- Young Ralph
- Zelko Frank
- Publication venue
- 'University of Toronto Press Inc. (UTPress)'
- Publication date
- Field of study
The Use of the Book of Proverbs in Systematic Theology
- Author
- Barth Karl
- Bavinck Herman
- Berkhof Louis
- Berkouwer G. C.
- Berkouwer G. C.
- Berkouwer G. C.
- Biedermann Alois Emanuel
- Boice James Montgomery
- Bolt John
- Bray Gerald Lewis
- Breckinridge Robert J.
- Bridges Charles
- Brunner Emil
- Buswell J Oliver
- Calvin John
- Carson D.A.
- Delitzsch Franz
- Diem Hermann
- Dorner Isaak
- du Barry Roger
- Ebeling Gerhard
- Erickson Millard
- Finlayson R. A.
- Fitzwater P. B.
- Fox Michael V.
- Fox Michael V.
- Frame John M.
- Fuhs Hans
- Gaffin Richard
- Gamble Richard
- Garrett James Leo
- Grenz Stanley J.
- Grudem Wayne A.
- Hodge Charles
- Horton Michael
- Hughes H. Maldwyn
- Härle Wilfried
- Johnson Alan
- Kidner Derek
- Kraus Hans-Joachim
- Loader J A
- Longman Tremper
- McKane William
- Morse Christopher
- Moule H. C. G.
- Murphy Roland E.
- Oden Thomas
- Oesterley W. O. E.
- Pannenberg Wolfhart
- Peckham John C.
- Perowne T. T.
- Pieper Francis
- Plöger Otto
- Pope William
- Ringgren Helmer
- Smith Henry
- Snyman S
- Strong Augustus
- Tatford Frederick
- Thielicke Helmut
- Thiessen Henry
- Turretin Francis
- van Oosterzee Johannes
- Vanhoozer Kevin
- Waltke Bruce K.
- Waltke Bruce K.
- Watson Richard
- Weber Otto
- Whybray R. N.
- à Brakel Wilhelmus
- Publication venue
- 'SAGE Publications'
- Publication date
- Field of study
Genome Sequence of the Brown Norway Rat Yields Insights Into Mammalian Evolution
- Author
- Abramzon Sofyia
- Abril Josep F.
- Adams Mark D.
- Adetobi Margaret
- Alexandersson Marina
- Amanatides Peter G.
- Andrews T. Dan
- Arumugam Manimozhiyan
- Baden-Tillson Holly
- Baertsch Robert
- Bailey Jeffrey A.
- Barnstead Mary
- Batzoglou Serafim
- Beatson Scott A.
- Birney Ewan
- Blakesley Robert W.
- Bork Peer
- Bosdet Ian
- Bouffard Gerard G.
- Bourque Guillaume
- Brandt Petra
- Bray Nicolas
- Brent Michael
- Bromberg Susan
- Brudno Michael
- Burch Paula E.
- Caccamo Mario
- Cahill Patrick
- Camara Francisco
- Caspi Anat
- Cawley Simon
- Celera A.
- Chakrabarti Kushal
- Chatterji Sourav
- Chen Rui
- Chen Yixin
- Chiaromonte Francesca
- Chin Soo
- Clamp Michele
- Clarke Laura
- Clawson Hiram
- Collins Francis
- Cooney A. J.
- Cooper David Neil
- Cooper Gregory M.
- Copley Richard R.
- Couronne Olivier
- Craig Venter J.
- Curwen Valerie
- D'Souza Lisa M.
- Daniels Sue
- de Jong Pieter J.
- Delgado Oliver
- DeRamo Christine
- Dewey Colin
- Doucette-Stamm Lynn
- Duarte Jose M.
- Dubchak Inna
- Dugan-Rocha Shannon
- Dunn Diane M.
- Durbin Richard
- Egan Amy
- Eichler Evan E.
- Elnitski Laura
- Emes Richard D.
- Eswara Pallavi
- Evans Cheryl A.
- Eyras Eduardo
- Fechtel Kim
- Fechtel Kim
- Felsenfeld Adam
- Ferriera Steve
- Fjell Chris
- Fosler Carl
- Fraser Claire M.
- Furey Terrence S.
- Ganten Detlev
- Geer Keita
- Gibbs Richard A.
- Gibbs Richard A.
- Gibbs Richard A.
- Gietzen Darryl
- Gill Rachel
- Glodek Anna
- Goesele Claudia
- Gonzalez-Garay Manuel L.
- Goodstadt Leo
- Green Eric D.
- Gu Zhiping
- Guigo Roderic
- Gullings-Handley Jo
- Gustafson Erik
- Guyer Mark
- Hardison Ross C.
- Haussler David
- Havlak Paul H.
- Hawes Alicia
- Himmelbauer Heinz
- Hines Sandra
- Hinrichs Angie S.
- Holt Robert A.
- Hou Minmei
- Huang Hui
- Hummel Oliver
- Hübner Norbert
- Jackson Andrew R.
- Jacob Howard J.
- James Durbin K.
- Jennings Don
- Jensen-Seaman Michael I.
- Jones Steven
- Kalafus Kenneth J.
- Kana Arnold
- Karolchik Donna
- Kent William J.
- Kolbe Diana
- Kraft Cheryl L.
- Kreitler Thomas
- Krzywinski Martin
- Kwitek Anne E.
- Lazar Jozef
- Lee Hong-Mei
- Lee Young-Ae
- Lehrach Hans
- Lewis Lora
- Li Bingshan
- Lindpaintner Klaus
- Liu Yue
- López-Otín Carlos
- Ma Bin
- Makova Kateryna
- Mar Albà M.
- Marra Marco
- Martin Kirt
- Mathewson Carrie
- McLeod Michael P.
- McPherson John
- Metzker Michael L.
- Miller Webb
- Milosavljevic Aleksandar
- Miner George
- Mockrin Stephen
- Mongin Emmanuel
- Monti Jan
- Morgan Margaret
- Mudunuri Uma
- Muzny Donna M.
- Nekrutenko Anton
- Nguyen Trixie
- Nierman William C.
- Nyakatura Gerald
- Okwuonu Geoffrey
- Old Susan
- Osoegawa Kazutoyo
- Pachter Lior
- Pasko Dean
- Payseur Bret A.
- Peterson Jane
- Pevzner Pavel A.
- Pfannkoch Cynthia M.
- Poliakov Alexander
- Ponting Chris P.
- Puente Xose S.
- Qian Wu Jia
- Qin Xiang
- Ren Yanru
- Rice Stephen
- Riemer Cathy
- Riethman Harold
- Rosenbloom Kate R.
- Roskin Krishna M.
- Rubin Edward M.
- Schein Jacqueline
- Scherer Steven
- Schmidt Jeanette
- Schulz Herbert
- Schwartz Scott
- Scott Graham
- Searle Stephen M.
- Shatsman Sofiya
- Shetty Jyoti
- Shteynberg David
- Siddiqui Asim
- Sidow Arend
- Sitter Cynthia
- Smit Arian
- Smith Douglas
- Smith Douglas
- Sodergren Erica J.
- Song Xing-Zhi
- Steffen David
- Stenson Peter
- Stevens Kristian
- Stone Eric A.
- Sutton Granger G.
- Suyama Mikita
- Taylor James
- Taylor Martin S.
- Tesler Glenn
- Tonellato Peter J.
- Torrents David
- Trask Barbara J.
- Trumbower Heather
- Tuzun Eray
- Twigger Simon
- Ureta-Vidal Abel
- Venter J. Craig
- Virk Davinder
- Vitt Ursula
- Volkov Andrei
- Wang Huajun
- Webber Caleb
- Weinstock George M.
- Weinstock George M.
- Weinstock George M.
- Weinstock Keith
- Weinstock Keith
- Weirauch Matt
- Weiss Robert B.
- Wheeler David A.
- Wingrove Jim
- Winter Eitan E.
- Woodage Trevor
- Woodwark Cara
- Worley Kim C.
- Worley Kim C.
- Wye Natasja
- Xing Heming
- Yang Shan
- Yap Von Bing
- Young Janet M.
- Zdobnov Evgeny
- Zhang Yi
- Zhang Zhengdong
- Zhao Shaying
- Zhu Baoli
- Zimdahl Heike
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2004
- Field of study
The laboratory rat (Rattus norvegicus) is an indispensable tool in experimental medicine and drug development, having made inestimable contributions to human health. We report here the genome sequence of the Brown Norway (BN) rat strain. The sequence represents a high-quality 'draft' covering over 90% of the genome. The BN rat sequence is the third complete mammalian genome to be deciphered, and three-way comparisons with the human and mouse genomes resolve details of mammalian evolution. This first comprehensive analysis includes genes and proteins and their relation to human disease, repeated sequences, comparative genome-wide studies of mammalian orthologous chromosomal regions and rearrangement breakpoints, reconstruction of ancestral karyotypes and the events leading to existing species, rates of variation, and lineage-specific and lineage-independent evolutionary events such as expansion of gene families, orthology relations and protein evolution
The DNA sequence of the human X chromosome
- Author
- Ainscough Rachael
- Ambrose Kerrie D
- Andrews T Daniel
- Ansari-Lari M Ali
- Aradhya Swaroop
- Ashurst Jennifer L
- Ashwell Robert I S
- Babbage Anne K
- Bagguley Claire L
- Ballabio Andrea
- Banerjee Ruby
- Barker Gary E
- Barlow Karen F
- Barrett Ian P
- Bates Karen N
- Beare David M
- Beasley Helen
- Beasley Oliver
- Beck Alfred
- Beck Stephan
- Bentley David R
- Bethel Graeme
- Bird Christine P
- Blechschmidt Karin
- Bonnin David
- Brady Nicola
- Bray-Allen Sarah
- Bridgeman Anne M
- Brown Andrew J
- Brown Mary J
- Bruford Elspeth A
- Buck David
- Buhay Christian
- Burch Paula
- Burford Deborah
- Burgess Joanne
- Burrill Wayne
- Burrows Christine
- Burton John
- Bye Jackie M
- Carder Carol
- Carrel Laura
- Carter Nigel P
- Chako Joseph
- Chapman Joanne C
- Chavez Dean
- Chen Ellson
- Chen Guan
- Chen Rui
- Chen Yuan
- Chen Zhijian
- Chinault Craig
- Ciccodicola Alfredo
- Clark Sue Y
- Clarke Graham
- Clee Chris M
- Clegg Sheila
- Clerc-Blankenburg Kerstin
- Clifford Karen
- Cobley Vicky
- Coffey Alison J
- Cole Charlotte G
- Connor Richard E
- Conquer Jen S
- Corby Nicole
- Coulson Alan
- Cree Andrew
- d'Urso Michele
- David Robert
- Davies Joy
- Davis Clay
- Davis John
- de Jong Pieter J
- Deadman Rebecca
- Delgado Oliver
- Deshazo Denise
- Dhami Pawandeep
- Ding Yan
- Dinh Huyen
- Dodsworth Steve
- Draper Heather
- Dugan-Rocha Shannon
- Dunham Andrew
- Dunn Matthew
- Durbin K James
- Durbin Richard
- Dutta Ireena
- Eades Tamsin
- Ellwood Matthew
- Emery-Cohen Alexandra
- Errington Helen
- Evans Kathryn L
- Faulkner Louisa
- Francis Fiona
- Frankish Adam
- Frankland John
- Fraser Audrey E
- Fulton Robert S
- Galgoczy Petra
- Gibbs Richard A
- Gilbert James
- Gill Rachel
- Glöckner Gernot
- Grafham Darren V
- Gregory Simon G
- Gribble Susan
- Griffiths Coline
- Grocock Russell
- Gu Yanghong
- Gunaratne Preethi
- Gwilliam Rhian
- Hamilton Cerissa
- Hart Elizabeth A
- Havlak Paul
- Hawes Alicia
- Heath Paul D
- Heitmann Katja
- Hennig Steffen
- Hernandez Judith
- Hillier Ladeana W
- Hinzmann Bernd
- Ho Sarah
- Hodgson Anne
- Hoffs Michael
- Howden Phillip J
- Howe Kevin L
- Howell Gareth R
- Hubbard Tim
- Huckle Elizabeth J
- Hume Jennifer
- Hunt Adrienne R
- Hunt Paul J
- Hunt Sarah E
- Hurles Matthew E
- Isherwood Judith
- Jacob Leni
- Johnson David
- Jones Matthew C
- Jones Sally
- Joseph Shirin S
- Keenan Stephen
- Kelly Susan
- Kershaw Joanne K
- Khan Ziad
- Kioschis Petra
- Klages Sven
- Knights Andrew J
- Kosiura Anna
- Kovar-Smith Christie
- Laird Gavin K
- Langford Cordelia
- Lawlor Stephanie
- Lehrach Hans
- Leversha Margaret
- Lewis Lora
- Liu Wen
- Lloyd Christine
- Lloyd David M
- Loulseged Hermela
- Loveland Jane E
- Lovell Frances L
- Lovell Jamieson D
- Lozado Ryan
- Lu Jing
- Lyne Rachael
- Ma Jie
- Maheshwari Manjula
- Matthews Lucy H
- McDowall Jennifer
- McLaren Stuart
- McLay Kirsten
- McMurray Amanda
- Meidl Patrick
- Meindl Alfons
- Meitinger Thomas
- Metzker Michael L
- Milne Sarah
- Miner George
- Minx Patrick J
- Mistry Shailesh L
- Morgan Margaret
- Morris Sidney
- Mullikin James C
- Muzny Donna
- Müller Ines
- Nelson David L
- Nguyen Ngoc
- Nordsiek Gabriele
- Nyakatura Gerald
- O'Dell Christopher N
- Okwuonu Geoffery
- Palmer Sophie
- Pandian Richard
- Parker David
- Parrish Julia
- Pasternak Shiran
- Patel Dina
- Pearce Alex V
- Pearson Danita M
- Pelan Sarah E
- Perez Lesette
- Platzer Matthias
- Porter Keith M
- Poustka Annemarie
- Ramser Juliane
- Ramsey Yvonne
- Reichwald Kathrin
- Reinhardt Richard
- Rhodes Susan
- Rice Catherine M
- Richards Stephen
- Ridler Kerry A
- Rogers Jane
- Rosenthal André
- Ross Mark T
- Scherer Steven
- Schlessinger David
- Schueler Mary G
- Scott Carol E
- Scott Graham
- Searle Stephen
- Sehra Harminder K
- Shaw-Smith Charles
- Shen Hua
- Sheridan Elizabeth M
- Shownkeen Ratna
- Skuce Carl D
- Smith Michelle L
- Sodergren Erica
- Sotheran Elizabeth C
- Steffen David
- Steingruber Helen E
- Steward Charles A
- Storey Roy
- Sudbrak Ralf
- Sulston John E
- Swann R Mark
- Swarbreck David
- Tabor Paul E
- Taudien Stefan
- Taylor Tineace
- Teague Brian
- Thomas Karen
- Thorpe Andrea
- Timms Kirsten
- Tracey Alan
- Trevanion Steve
- Tromans Anthony C
- Vaudin Mark
- Verduzco Daniel
- Villasana Donna
- Waldron Lenee
- Wall Melanie
- Wang Qiaoyan
- Warren James
- Warry Georgina L
- Waterston Robert H
- Wei Xuehong
- Weinstock George
- Wen Gaiping
- West Anthony
- Wheeler David A
- Whitehead Siobhan L
- Whiteley Mathew N
- Whittaker Adam
- Wilkinson Jane E
- Willard Huntington F
- Willey David L
- Williams Gabrielle
- Williams Leanne
- Williamson Angela
- Williamson Helen
- Wilming Laurens
- Wilson Richard K
- Woodmansey Rebecca L
- Worley Kim C
- Wray Paul W
- Yen Jennifer
- Zhang Jingkun
- Zhou Jianling
- Zoghbi Huda
- Zorilla Sara
- Publication venue
- Publication date
- 17/03/2005
- Field of study
The human X chromosome has a unique biology that was shaped by its evolution as the sex chromosome shared by males and females. We have determined 99.3% of the euchromatic sequence of the X chromosome. Our analysis illustrates the autosomal origin of the mammalian sex chromosomes, the stepwise process that led to the progressive loss of recombination between X and Y, and the extent of subsequent degradation of the Y chromosome. LINE1 repeat elements cover one-third of the X chromosome, with a distribution that is consistent with their proposed role as way stations in the process of X-chromosome inactivation. We found 1,098 genes in the sequence, of which 99 encode proteins expressed in testis and in various tumour types. A disproportionately high number of mendelian diseases are documented for the X chromosome. Of this number, 168 have been explained by mutations in 113 X-linked genes, which in many cases were characterized with the aid of the DNA sequence
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- Atajanyan Emmanuel
- Aufdemberge C. T.
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- Aymer Margaret
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- Bakhtin Mikhail
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- Baur F. C.
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- Bedford Richard
- Blake William
- Blomberg Craig
- Blomberg Craig
- Bloom Harold
- Bonhoeffer Dietrich
- Bray Gerald
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- Buechner Frederick
- Buechner Frederick
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- Publication venue
- 'Wiley'
- Publication date
- Field of study