671 research outputs found

    Stephen J. Shoemaker, The Death of a Prophet. The End of Muhammad’s Life and the Beginning of Islam

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    Avec cet ouvrage, Stephen J. Shoemaker (SJS), qui est avant tout un spĂ©cialiste du Christianisme, en particulier des traditions primitives concernant la Vierge Marie (The Ancient Traditions of the Virgin Mary’s Domition and Assumption, Oxford University Press, 2002 ; The Life of the Virgin attributed to Maximus the Confessor, Yale University Press, 2012), se lance un vĂ©ritable dĂ©fi, en rĂ©orientant ses recherches vers l’histoire et l’historiographie des dĂ©buts de l’islam. L’auteur se propose d..

    Anne-Sylvie Boisliveau, Le Coran par lui-mĂȘme. Vocabulaire et argumentation du discours coranique autorĂ©fĂ©rentiel

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    L’ouvrage d’Anne-Sylvie Boisliveau est partiellement tirĂ© de la thĂšse qu’elle a soutenue Ă  l’UniversitĂ© Aix-Marseille (2010), sous la direction de Denis Gril. L’auteur propose de complĂ©ter « les Ă©tudes existantes sur le Coran » (p. 6) Ă  travers « un examen approfondi du discours autorĂ©fĂ©rentiel coranique » (p. 6), dans la continuitĂ© des travaux existants (voir parmi d’autres, D. Madigan, The Qur’ñn’s self image: writing and authority in Islam’s scripture, Princeton University Press, 2001). Ma..

    Fred M. Donner, Muhammad and the Believers: At the Origins of Islam

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    Le livre de Fred Donner est un Ă©vĂ©nement historiographique important dans le champ des Ă©tudes portant sur l’histoire des dĂ©buts de l’Islam. Comme le titre le laisse Ă  penser, il ne s’agit pas d’un Ă©niĂšme livre sur le ProphĂšte Muhammad (citons Ă  ce titre la biographie classique de MontgomĂ©ry Watt en deux volumes, Muhammad at Mecca, 1953 ; Muhammad at Medina, 1956). L’historien amĂ©ricain, professeur Ă  l’UniversitĂ© de Chicago, propose au contraire, dans ce livre composĂ© de cinq parties, une hist..

    Les représentations sociales des cadres pédagogiques concernant la scolarisation des autistes

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    Cette recherche s’inscrit dans la perspective gĂ©nĂ©rale de l’étude des conditions de rĂ©ussite de l’inclusion des personnes Ă  besoins spĂ©cifiques. Nous nous contentons, dans la prĂ©sente Ă©tude, de prendre en considĂ©ration le cas des apprenants autistes afin de cerner les reprĂ©sentations du corps pĂ©dagogique (directeurs d’établissements, enseignants
) concernant leur inclusion dans l’école publique. Le travail sur le noyau de sens des reprĂ©sentations sociales de la scolarisation des autistes chez les cadres pĂ©dagogiques, nous a permis de comprendre que ces reprĂ©sentations ancrĂ©es dans le quotidien du corps pĂ©dagogique sont dues spĂ©cialement au manque de formation dans ce domaine et Ă  une mĂ©connaissance presque gĂ©nĂ©rale du TSA. Les recommandations qui closent cette Ă©tude renvoient aux dĂ©cisions Ă  prendre pour rĂ©ussir l’inclusion des apprenants Ă  besoins spĂ©cifiques en gĂ©nĂ©ral et les autistes en particulier

    The ocean sampling day consortium

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    Ocean Sampling Day was initiated by the EU-funded Micro B3 (Marine Microbial Biodiversity, Bioinformatics, Biotechnology) project to obtain a snapshot of the marine microbial biodiversity and function of the world’s oceans. It is a simultaneous global mega-sequencing campaign aiming to generate the largest standardized microbial data set in a single day. This will be achievable only through the coordinated efforts of an Ocean Sampling Day Consortium, supportive partnerships and networks between sites. This commentary outlines the establishment, function and aims of the Consortium and describes our vision for a sustainable study of marine microbial communities and their embedded functional traits

    The Ocean Sampling Day Consortium

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    Ocean Sampling Day was initiated by the EU-funded Micro B3 (Marine Microbial Biodiversity, Bioinformatics, Biotechnology) project to obtain a snapshot of the marine microbial biodiversity and function of the world’s oceans. It is a simultaneous global mega-sequencing campaign aiming to generate the largest standardized microbial data set in a single day. This will be achievable only through the coordinated efforts of an Ocean Sampling Day Consortium, supportive partnerships and networks between sites. This commentary outlines the establishment, function and aims of the Consortium and describes our vision for a sustainable study of marine microbial communities and their embedded functional traits

    Laparoscopy in management of appendicitis in high-, middle-, and low-income countries: a multicenter, prospective, cohort study.

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    BACKGROUND: Appendicitis is the most common abdominal surgical emergency worldwide. Differences between high- and low-income settings in the availability of laparoscopic appendectomy, alternative management choices, and outcomes are poorly described. The aim was to identify variation in surgical management and outcomes of appendicitis within low-, middle-, and high-Human Development Index (HDI) countries worldwide. METHODS: This is a multicenter, international prospective cohort study. Consecutive sampling of patients undergoing emergency appendectomy over 6 months was conducted. Follow-up lasted 30 days. RESULTS: 4546 patients from 52 countries underwent appendectomy (2499 high-, 1540 middle-, and 507 low-HDI groups). Surgical site infection (SSI) rates were higher in low-HDI (OR 2.57, 95% CI 1.33-4.99, p = 0.005) but not middle-HDI countries (OR 1.38, 95% CI 0.76-2.52, p = 0.291), compared with high-HDI countries after adjustment. A laparoscopic approach was common in high-HDI countries (1693/2499, 67.7%), but infrequent in low-HDI (41/507, 8.1%) and middle-HDI (132/1540, 8.6%) groups. After accounting for case-mix, laparoscopy was still associated with fewer overall complications (OR 0.55, 95% CI 0.42-0.71, p < 0.001) and SSIs (OR 0.22, 95% CI 0.14-0.33, p < 0.001). In propensity-score matched groups within low-/middle-HDI countries, laparoscopy was still associated with fewer overall complications (OR 0.23 95% CI 0.11-0.44) and SSI (OR 0.21 95% CI 0.09-0.45). CONCLUSION: A laparoscopic approach is associated with better outcomes and availability appears to differ by country HDI. Despite the profound clinical, operational, and financial barriers to its widespread introduction, laparoscopy could significantly improve outcomes for patients in low-resource environments. TRIAL REGISTRATION: NCT02179112

    Global economic burden of unmet surgical need for appendicitis

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    Background: There is a substantial gap in provision of adequate surgical care in many low-and middle-income countries. This study aimed to identify the economic burden of unmet surgical need for the common condition of appendicitis. Methods: Data on the incidence of appendicitis from 170 countries and two different approaches were used to estimate numbers of patients who do not receive surgery: as a fixed proportion of the total unmet surgical need per country (approach 1); and based on country income status (approach 2). Indirect costs with current levels of access and local quality, and those if quality were at the standards of high-income countries, were estimated. A human capital approach was applied, focusing on the economic burden resulting from premature death and absenteeism. Results: Excess mortality was 4185 per 100 000 cases of appendicitis using approach 1 and 3448 per 100 000 using approach 2. The economic burden of continuing current levels of access and local quality was US 92492millionusingapproach1and92 492 million using approach 1 and 73 141 million using approach 2. The economic burden of not providing surgical care to the standards of high-income countries was 95004millionusingapproach1and95 004 million using approach 1 and 75 666 million using approach 2. The largest share of these costs resulted from premature death (97.7 per cent) and lack of access (97.0 per cent) in contrast to lack of quality. Conclusion: For a comparatively non-complex emergency condition such as appendicitis, increasing access to care should be prioritized. Although improving quality of care should not be neglected, increasing provision of care at current standards could reduce societal costs substantially

    Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy

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    Background The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery has not been assessed on a global scale. The aim of this study was to evaluate reported checklist use in emergency settings and examine the relationship with perioperative mortality in patients who had emergency laparotomy. Methods In two multinational cohort studies, adults undergoing emergency laparotomy were compared with those having elective gastrointestinal surgery. Relationships between reported checklist use and mortality were determined using multivariable logistic regression and bootstrapped simulation. Results Of 12 296 patients included from 76 countries, 4843 underwent emergency laparotomy. After adjusting for patient and disease factors, checklist use before emergency laparotomy was more common in countries with a high Human Development Index (HDI) (2455 of 2741, 89.6 per cent) compared with that in countries with a middle (753 of 1242, 60.6 per cent; odds ratio (OR) 0.17, 95 per cent c.i. 0.14 to 0.21, P <0001) or low (363 of 860, 422 per cent; OR 008, 007 to 010, P <0.001) HDI. Checklist use was less common in elective surgery than for emergency laparotomy in high-HDI countries (risk difference -94 (95 per cent c.i. -11.9 to -6.9) per cent; P <0001), but the relationship was reversed in low-HDI countries (+121 (+7.0 to +173) per cent; P <0001). In multivariable models, checklist use was associated with a lower 30-day perioperative mortality (OR 0.60, 0.50 to 073; P <0.001). The greatest absolute benefit was seen for emergency surgery in low- and middle-HDI countries. Conclusion Checklist use in emergency laparotomy was associated with a significantly lower perioperative mortality rate. Checklist use in low-HDI countries was half that in high-HDI countries.Peer reviewe
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