69 research outputs found
Measurements of the Production, Decay and Properties of the Top Quark: A Review
With the full Tevatron Run II and early LHC data samples, the opportunity for
furthering our understanding of the properties of the top quark has never been
more promising. Although the current knowledge of the top quark comes largely
from Tevatron measurements, the experiments at the LHC are poised to probe
top-quark production and decay in unprecedented regimes. Although no current
top quark measurements conclusively contradict predictions from the standard
model, the precision of most measurements remains statistically limited.
Additionally, some measurements, most notably the forward-backward asymmetry in
top quark pair production, show tantalizing hints of beyond-the-Standard-Model
dynamics. The top quark sample is growing rapidly at the LHC, with initial
results now public. This review examines the current status of top quark
measurements in the particular light of searching for evidence of new physics,
either through direct searches for beyond the standard model phenomena or
indirectly via precise measurements of standard model top quark properties
Strong, weak and flavor scalar triplets for the CDF Wjj anomaly
A model describing the 4.1\sigma\ Wjj anomaly observed by the CDF experiment
at the Tevatron collider is introduced. It features new scalar particles which
are charged both under the SU(3)_C and the SU(2)_L gauge groups and which
couple to pairs of quarks. We introduce several identical replicas of the
scalar multiplets in order to leave an unbroken U(3)_Q x U(3)_U x U(3)_D flavor
symmetry to satisfy the constraints coming from flavor physics. We discuss the
LHC reach on the new scalar resonances both in the resonant production channel
(with the Wjj final state) and in the QCD pair production channel (with the 4j
final state).Comment: 17 pages, 6 figures and 4 table
Running coupling in electroweak interactions of leptons from f(R)-gravity with torsion
The f(R)-gravitational theory with torsion is considered for one family of
leptons; it is found that the torsion tensor gives rise to interactions having
the structure of the weak forces while the intrinsic non-linearity of the f(R)
function provides an energy-dependent coupling: in this way, torsional f(R)
gravity naturally generates both structure and strength of the electroweak
interactions among leptons. This implies that the weak interactions among the
lepton fields could be addressed as a geometric effect due to the interactions
among spinors induced by the presence of torsion in the most general f(R)
gravity. Phenomenological considerations are addressed.Comment: 9 pages. arXiv admin note: text overlap with arXiv:1012.5529 by other
author
Towards an understanding of heavy baryon spectroscopy
The recent observation at CDF and D0 of , and
baryons opens the door to the advent of new states in the bottom baryon sector.
The states measured provide sufficient constraints to fix the parameters of
phenomenological models. One may therefore consistently predict the full bottom
baryon spectra. For this purpose we have solved exactly the three-quark problem
by means of the Faddeev method in momentum space. We consider our guidance may
help experimentalists in the search for new bottom baryons and their findings
will help in constraining further the phenomenological models. We identify
particular states whose masses may allow to discriminate between the dynamics
for the light-quark pairs predicted by different phenomenological models.
Within the same framework we also present results for charmed, doubly charmed,
and doubly bottom baryons. Our results provide a restricted possible assignment
of quantum numbers to recently reported charmed baryon states. Some of them are
perfectly described by wave excitations with , as the , , and .Comment: Accepted for publication in Eur. Phys. J.
Comprehensive evaluation of coding region point mutations in microsatellite-unstable colorectal cancer
Microsatellite instability (MSI) leads to accumulation of an excessive number of mutations in the genome, mostly small insertions and deletions. MSI colorectal cancers (CRCs), however, also contain more point mutations than microsatellite-stable (MSS) tumors, yet they have not been as comprehensively studied. To identify candidate driver genes affected by point mutations in MSI CRC, we ranked genes based on mutation significance while correcting for replication timing and gene expression utilizing an algorithm, MutSigCV. Somatic point mutation data from the exome kit-targeted area from 24 exome-sequenced sporadic MSI CRCs and respective normals, and 12 whole-genome-sequenced sporadic MSI CRCs and respective normals were utilized. The top 73 genes were validated in 93 additional MSI CRCs. The MutSigCV ranking identified several well-established MSI CRC driver genes and provided additional evidence for previously proposed CRC candidate genes as well as shortlisted genes that have to our knowledge not been linked to CRC before. Two genes, SMARCB1 and STK38L, were also functionally scrutinized, providing evidence of a tumorigenic role, for SMARCB1 mutations in particular. © 2018 The Authors. Published under the terms of the CC BY 4.0 licensePeer reviewe
Heavy quarkonium: progress, puzzles, and opportunities
A golden age for heavy quarkonium physics dawned a decade ago, initiated by
the confluence of exciting advances in quantum chromodynamics (QCD) and an
explosion of related experimental activity. The early years of this period were
chronicled in the Quarkonium Working Group (QWG) CERN Yellow Report (YR) in
2004, which presented a comprehensive review of the status of the field at that
time and provided specific recommendations for further progress. However, the
broad spectrum of subsequent breakthroughs, surprises, and continuing puzzles
could only be partially anticipated. Since the release of the YR, the BESII
program concluded only to give birth to BESIII; the -factories and CLEO-c
flourished; quarkonium production and polarization measurements at HERA and the
Tevatron matured; and heavy-ion collisions at RHIC have opened a window on the
deconfinement regime. All these experiments leave legacies of quality,
precision, and unsolved mysteries for quarkonium physics, and therefore beg for
continuing investigations. The plethora of newly-found quarkonium-like states
unleashed a flood of theoretical investigations into new forms of matter such
as quark-gluon hybrids, mesonic molecules, and tetraquarks. Measurements of the
spectroscopy, decays, production, and in-medium behavior of c\bar{c}, b\bar{b},
and b\bar{c} bound states have been shown to validate some theoretical
approaches to QCD and highlight lack of quantitative success for others. The
intriguing details of quarkonium suppression in heavy-ion collisions that have
emerged from RHIC have elevated the importance of separating hot- and
cold-nuclear-matter effects in quark-gluon plasma studies. This review
systematically addresses all these matters and concludes by prioritizing
directions for ongoing and future efforts.Comment: 182 pages, 112 figures. Editors: N. Brambilla, S. Eidelman, B. K.
Heltsley, R. Vogt. Section Coordinators: G. T. Bodwin, E. Eichten, A. D.
Frawley, A. B. Meyer, R. E. Mitchell, V. Papadimitriou, P. Petreczky, A. A.
Petrov, P. Robbe, A. Vair
Measurement of the CP-violating phase \phi s in Bs->J/\psi\pi+\pi- decays
Measurement of the mixing-induced CP-violating phase phi_s in Bs decays is of
prime importance in probing new physics. Here 7421 +/- 105 signal events from
the dominantly CP-odd final state J/\psi pi+ pi- are selected in 1/fb of pp
collision data collected at sqrt{s} = 7 TeV with the LHCb detector. A
time-dependent fit to the data yields a value of
phi_s=-0.019^{+0.173+0.004}_{-0.174-0.003} rad, consistent with the Standard
Model expectation. No evidence of direct CP violation is found.Comment: 15 pages, 10 figures; minor revisions on May 23, 201
Measurement of the branching fraction
The branching fraction is measured in a data sample
corresponding to 0.41 of integrated luminosity collected with the LHCb
detector at the LHC. This channel is sensitive to the penguin contributions
affecting the sin2 measurement from The
time-integrated branching fraction is measured to be . This is the most precise measurement to
date
Search for direct production of charginos and neutralinos in events with three leptons and missing transverse momentum in √s = 7 TeV pp collisions with the ATLAS detector
A search for the direct production of charginos and neutralinos in final states with three electrons or muons and missing transverse momentum is presented. The analysis is based on 4.7 fb−1 of proton–proton collision data delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in three signal regions that are either depleted or enriched in Z-boson decays. Upper limits at 95% confidence level are set in R-parity conserving phenomenological minimal supersymmetric models and in simplified models, significantly extending previous results
Germline determinants of the somatic mutation landscape in 2,642 cancer genomes
Cancers develop through somatic mutagenesis, however germline genetic variation can markedly contribute to tumorigenesis via diverse mechanisms. We discovered and phased 88 million germline single nucleotide variants, short insertions/deletions, and large structural variants in whole genomes from 2,642 cancer patients, and employed this genomic resource to study genetic determinants of somatic mutagenesis across 39 cancer types. Our analyses implicate damaging germline variants in a variety of cancer predisposition and DNA damage response genes with specific somatic mutation patterns. Mutations in the MBD4 DNA glycosylase gene showed association with elevated C>T mutagenesis at CpG dinucleotides, a ubiquitous mutational process acting across tissues. Analysis of somatic structural variation exposed complex rearrangement patterns, involving cycles of templated insertions and tandem duplications, in BRCA1-deficient tumours. Genome-wide association analysis implicated common genetic variation at the APOBEC3 gene cluster with reduced basal levels of somatic mutagenesis attributable to APOBEC cytidine deaminases across cancer types. We further inferred over a hundred polymorphic L1/LINE elements with somatic retrotransposition activity in cancer. Our study highlights the major impact of rare and common germline variants on mutational landscapes in cancer
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