533 research outputs found
Experimental results for the Eppler 387 airfoil at low Reynolds numbers in the Langley low-turbulence pressure tunnel
Experimental results were obtained for an Eppler 387 airfoil in the Langley Low Turbulence Pressure Tunnel. The tests were conducted over a Mach number range from 0.03 to 0.13 and a chord Reynolds number range for 60,000 to 460,000. Lift and pitching moment data were obtained from airfoil surface pressure measurements and drag data for wake surveys. Oil flow visualization was used to determine laminar separation and turbulent reattachment locations. Comparisons of these results with data on the Eppler 387 airfoil from two other facilities as well as the Eppler airfoil code are included
Nurses\u27 Alumnae Association Bulletin - Volume 6 Number 9
Remember the Relief Fund
Welcome! Miss Childs
Financial Report
Calendar of Coming Events
Lest You Forget!
Attention
Review of the Alumnae Association Meetings
Institutional Staff Nurses\u27 Section
Report of Staff Activities - 1947-1948
Private Duty Section
The White Haven Division
Barton Memorial Division
Remember the Relief Fund
Student Nurses\u27 Activities
Jefferson Scores Again
The Clara Melville Scholarship Fund
Interesting Activities of the Nurses\u27 Home Committee of the Women\u27s Board
Exclusive for Nurses
Changes in the Maternity Division
Gray Lady Musical Therapy Service
Memorial Service Honoring Mrs. Bessie Dobson Altemus
The Blood Donor Center
The Hospital Pharmacy
Medical College News
Remember the Relief Fund
Administrative Staff and Faculty of the School of Nursing
Streptomycin
Changes in the Staff at Jefferson Hospital
Care of the Thoracic Surgical Patient
Miscellaneous Items
Marriages
New Arrivals
Deaths
The Bulletin Committee
Attention, Alumnae
New Addresse
Nurses\u27 Alumnae Association Bulletin - Volume 6 Number 10
Financial Report
Calendar of Events
Attention, Class of 1945!
Miss Shafer Retires
Review of the Alumnae Association Meetings
Institutional Staff Nurses\u27 Section
Report of Staff Activites - 1948-1949
The Staff
Stockings! Stockings! Stockings!
Pop-Up Toaster
It\u27s Not Too Soon
Any White Elephants?
Private Duty Section
The Jefferson Hospital Private Duty Nurses\u27 Register
Report for Barton Memorial Hospital
Progress of the Orthopedic Department
Just Under the Date Line
Pediatrics at Jefferson
Controlled Respiration in Anesthesia
Anesthesia Progress
Physical Advances at Jefferson During the Past Year
The White Haven Division
The Clara Melville Scholarship Fund
The Relief Fund
The Busy Year for the Nurses\u27 Home Committee of the Women\u27s Board
The Gray Ladies
Memories
Lost
Miscellaneous Items
Medical College News
Marriages
Births
Deaths
Condolences
Prizes
District No. 1 Dues
Help! Help! Help!
Jap Prison School Spurs Nurse to Win University Degree
Twenty Ways to Kill an Organization
The Bulletin Committee
Attention, Alumnae
New Addresse
The USNO-B Catalog
USNO-B is an all-sky catalog that presents positions, proper motions,
magnitudes in various optical passbands, and star/galaxy estimators for
1,042,618,261 objects derived from 3,643,201,733 separate observations. The
data were obtained from scans of 7,435 Schmidt plates taken for the various sky
surveys during the last 50 years. USNO-B1.0 is believed to provide all-sky
coverage, completeness down to V = 21, 0.2 arcsecond astrometric accuracy at
J2000, 0.3 magnitude photometric accuracy in up to five colors, and 85%
accuracy for distinguishing stars from non-stellar objects. A brief discussion
of various issues is given here, but the actual data are available from
http://www.nofs.navy.mil and other sites.Comment: Accepted by Astronomical Journa
SNL evaluation of Gigabit Passive Optical Networks (GPON).
Gigabit Passive Optical Networks (GPON) is a networking technology which offers the potential to provide significant cost savings to Sandia National Laboratories in the area of network operations. However, a large scale GPON deployment requires a significant investment in equipment and infrastructure. Before a large scale GPON system was acquired and built, a small GPON system manufactured by Motorola was acquired and tested. The testing performed was to determine the suitability of GPON for use at SNL. This report documents that testing. This report presents test results of GPON system consisting of Motorola and Juniper equipment. The GPON system was tested in areas of data throughput, video conferencing, VOIP, security, and operations and management. The GPON system performed well in almost all areas. GPON will not meet the needs of the low percentage of users requiring a true 1-10 Gbps network connection. GPON will also most likely not meet the need of some servers requiring dedicated throughput of 1-10 Gbps. Because of that, there will be some legacy network connections that must remain. If these legacy network connections can not be reduced to a bare minimum and possibly consolidated to a few locations, any cost savings gained by switching to GPON will be negated by maintaining two networks. A contract has been recently awarded for new GPON equipment with larger buffers. This equipment should improve performance and further reduce the need for legacy network connections. Because GPON has fewer components than a typical hierarchical network, it should be easier to manage. For the system tested, the management was performed by using the AXSVison client. Access to the client must be tightly controlled, because if client/server communications are compromised, security will be an issue. As with any network, the reliability of individual components will determine overall system reliability. There were no failures with the routers, OLT, or Sun Workstation Management platform. There were however four ONTs that failed. Because of the small sample size of 64, and the fact that some of the ONTs were used units, no conclusions can be made. However, ONT reliability is an area of concern. Access to the fiber plant that GPON requires must be tightly controlled and all changes documented. The undocumented changes that were performed in the GPON test lab demonstrated the need for tight control and documentation. In summary, GPON should be able to meet the needs of most network users at Sandia National Laboratories. Because it supports voice, video, and data, it positions Sandia National Laboratories to deploy these services to the desktop. For the majority of corporate network users at Sandia National Laboratories GPON should be a suitable replacement for the legacy network
Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis
BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London
Characterization of Neutralizing Profiles in HIV-1 Infected Patients from whom the HJ16, HGN194 and HK20 mAbs were Obtained
Several new human monoclonal antibodies (mAbs) with a neutralizing potential across different subtypes have recently been described. Three mAbs, HJ16, HGN194 and HK20, were obtained from patients within the HIV-1 cohort of the Institute of Tropical Medicine (ITM). Our aim was to generate immunization antibodies equivalent to those seen in plasma. Here, we describe the selection and characterization of patient plasma and their mAbs, using a range of neutralization assays, including several peripheral blood mononuclear cell (PBMC) based assays and replicating primary viruses as well as cell line based assays and pseudoviruses (PV). The principal criterion for selection of patient plasma was the activity in an ‘extended incubation phase’ PBMC assay. Neutralizing Abs, derived from their memory B cells, were then selected by ELISA with envelope proteins as solid phase. MAbs were subsequently tested in a high-throughput HOS-PV assay to assess functional neutralization. The present study indicates that the strong profiles in the patients' plasma were not solely due to antibodies represented by the newly isolated mAbs. Although results from the various assays were divergent, they by and large indicate that neutralizing Abs to other epitopes of the HIV-1 envelope are present in the plasma and synergy between Abs may be important. Thus, the spectrum of the obtained mAbs does not cover the range of cross-reactivity seen in plasma in these carefully selected patients irrespective of which neutralization assay is used. Nevertheless, these mAbs are relevant for immunogen discovery because they bind to the recombinant glycoproteins to which the immune response needs to be targeted in vivo. Our observations illustrate the remaining challenges required for successful immunogen design and development
Alignment of the CMS tracker with LHC and cosmic ray data
© CERN 2014 for the benefit of the CMS collaboration, published under the terms of the Creative Commons Attribution 3.0 License by IOP Publishing Ltd and Sissa Medialab srl. Any further distribution of this work must maintain attribution to the author(s) and the published article's title, journal citation and DOI.The central component of the CMS detector is the largest silicon tracker ever built. The precise alignment of this complex device is a formidable challenge, and only achievable with a significant extension of the technologies routinely used for tracking detectors in the past. This article describes the full-scale alignment procedure as it is used during LHC operations. Among the specific features of the method are the simultaneous determination of up to 200 000 alignment parameters with tracks, the measurement of individual sensor curvature parameters, the control of systematic misalignment effects, and the implementation of the whole procedure in a multi-processor environment for high execution speed. Overall, the achieved statistical accuracy on the module alignment is found to be significantly better than 10μm
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