101 research outputs found

    Transport of a quantum degenerate heteronuclear Bose-Fermi mixture in a harmonic trap

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    We report on the transport of mixed quantum degenerate gases of bosonic 87Rb and fermionic 40K in a harmonic potential provided by a modified QUIC trap. The samples are transported over a distance of 6 mm to the geometric center of the anti-Helmholtz coils of the QUIC trap. This transport mechanism was implemented by a small modification of the QUIC trap and is free of losses and heating. It allows all experiments using QUIC traps to use the highly homogeneous magnetic fields that can be created in the center of a QUIC trap and improves the optical access to the atoms, e.g., for experiments with optical lattices. This mechanism may be cascaded to cover even larger distances for applications with quantum degenerate samples.Comment: 7 pages, 8 figure

    Mutations in DDX3X Are a Common Cause of Unexplained Intellectual Disability with Gender-Specific Effects on Wnt Signaling

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    Intellectual disability (ID) affects approximately 1%-3% of humans with a gender bias toward males. Previous studies have identified mutations in more than 100 genes on the X chromosome in males with ID, but there is less evidence for de novo mutations on the X chromosome causing ID in females. In this study we present 35 unique deleterious de novo mutations in DDX3X identified by whole exome sequencing in 38 females with ID and various other features including hypotonia, movement disorders, behavior problems, corpus callosum hypoplasia, and epilepsy. Based on our findings, mutations in DDX3X are one of the more common causes of ID, accounting for 1%-3% of unexplained ID in females. Although no de novo DDX3X mutations were identified in males, we present three families with segregating missense mutations in DDX3X, suggestive of an X-linked recessive inheritance pattern. In these families, all males with the DDX3X variant had ID, whereas carrier females were unaffected. To explore the pathogenic mechanisms accounting for the differences in disease transmission and phenotype between affected females and affected males with DDX3X missense variants, we used canonical Wnt defects in zebrafish as a surrogate measure of DDX3X function in vivo. We demonstrate a consistent loss-of-function effect of all tested de novo mutations on the Wnt pathway, and we further show a differential effect by gender. The differential activity possibly reflects a dose-dependent effect of DDX3X expression in the context of functional mosaic females versus one-copy males, which reflects the complex biological nature of DDX3X mutations

    Triangulations and Severi varieties

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    We consider the problem of constructing triangulations of projective planes over Hurwitz algebras with minimal numbers of vertices. We observe that the numbers of faces of each dimension must be equal to the dimensions of certain representations of the automorphism groups of the corresponding Severi varieties. We construct a complex involving these representations, which should be considered as a geometric version of the (putative) triangulations

    Physics of the HL-LHC, and Perspectives at the HE-LHC

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    Planck intermediate results X : Physics of the hot gas in the Coma cluster

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    Peer reviewe

    Planck Intermediate Results II: Comparison of Sunyaev–Zeldovich measurements from Planck and from the Arcminute Microkelvin Imager for 11 galaxy clusters

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    A comparison is presented of Sunyaev–Zeldovich measurements for 11 galaxy clusters as obtained by Planck and by the ground-based interferom- eter, the Arcminute Microkelvin Imager. Assuming a universal spherically-symmetric Generalised Navarro, Frenk & White (GNFW) model for the cluster gas pressure profile, we jointly constrain the integrated Compton-Y parameter (Y500) and the scale radius (θ500) of each cluster. Our resulting constraints in the Y500 − θ500 2D parameter space derived from the two instruments overlap significantly for eight of the clusters, although, overall, there is a tendency for AMI to find the Sunyaev–Zeldovich signal to be smaller in angular size and fainter than Planck. Significant discrepancies exist for the three remaining clusters in the sample, namely A1413, A1914, and the newly-discovered Planck cluster PLCKESZ G139.59+24.18. The robustness of the analysis of both the Planck and AMI data is demonstrated through the use of detailed simulations, which also discount confusion from residual point (radio) sources and from diffuse astrophysical foregrounds as possible explanations for the discrepancies found. For a subset of our cluster sample, we have investigated the dependence of our results on the assumed pressure profile by repeating the analysis adopting the best-fitting GNFW profile shape which best matches X-ray observations. Adopting the best-fitting profile shape from the X-ray data does not, in general, resolve the discrepancies found in this subset of five clusters. Though based on a small sample, our results suggest that the adopted GNFW model may not be sufficiently flexible to describe clusters universally

    Higher harmonic anisotropic flow measurements of charged particles in Pb-Pb collisions at 2.76 TeV

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    We report on the first measurement of the triangular v3v_3, quadrangular v4v_4, and pentagonal v5v_5 charged particle flow in Pb-Pb collisions at 2.76 TeV measured with the ALICE detector at the CERN Large Hadron Collider. We show that the triangular flow can be described in terms of the initial spatial anisotropy and its fluctuations, which provides strong constraints on its origin. In the most central events, where the elliptic flow v2v_2 and v3v_3 have similar magnitude, a double peaked structure in the two-particle azimuthal correlations is observed, which is often interpreted as a Mach cone response to fast partons. We show that this structure can be naturally explained from the measured anisotropic flow Fourier coefficients.Comment: 10 pages, 4 figures, published version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/387

    Urinary, Circulating, and Tissue Biomonitoring Studies Indicate Widespread Exposure to Bisphenol A

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    virginiana

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    Fragaria virginiana Mill.fraisier des champsWild strawberryCarbondale Road; 1km past Lynx Creek Campground Jct.B. GorhamOpen S-SE. facing meadow, S. side of Carbondale Rd., above creek1351 mGeum triflorum, Balsamorhiza sagittata, Lomatium triternatum, Maianthemum stellatum, Primula conjugens, Delphinium bicolor, Rosa sp., Cerastium arvense, Achillea millefolium, Amelanchier alnifolia, Lupinus sericeus, Viola nuttallii, Arctostaphylos uva-ursi, Populus tremuloide
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