A Review of \u3cem\u3eTeaching as a Moral Practice: Defining, Developing, and Assessing Professional Dispositions in Teacher Education\u3c/em\u3e

A review of the book Teaching as a Moral Practice: Defining, Developing, and Assessing Professional Dispositions in Teacher Education, by Peter C. Murrell Jr., Mary Diez, Sharon Feiman-Nemser, and Deborah L. Schussler (Harvard University Press, 2010)

The Wisdom of Practice Meets the Pursuit of Scientific Inquiry. A Response to Scientifically Based Research and Teacher Agency: Combating \u27Conspiracies of Certainty\u27

Stemhagen and Nomi argued that the influence of many contemporary forms of education research, especially scientifically based research, inevitably position teachers as problems rather than as active agents whose judgement is indivisible from the activity of teaching and learning. We share the authors’ intuitions and concerns about the divide between research and teaching but also wonder if there remains another way into some of the concerns they raise. We start with a different question but one we think is fundamental to Stemhagen and Nomi’s critique: How do the findings of empirical research make their way into the work of teaching? By answering this question, we hope to reframe the authors’ concerns and reconsider their recommendation that teachers become participatory action researchers. It is distressing that practitioners and researchers have not yet found ways (despite the insights of John Dewey and other theorist and practitioners over more than a century) to substantively account for each others’ growing understanding because both the wisdom of practice and the pursuit of scientific insight are central to the effective and generative practice of educating children and adults

The state of the Martian climate

60°N was +2.0°C, relative to the 1981–2010 average value (Fig. 5.1). This marks a new high for the record. The average annual surface air temperature (SAT) anomaly for 2016 for land stations north of starting in 1900, and is a significant increase over the previous highest value of +1.2°C, which was observed in 2007, 2011, and 2015. Average global annual temperatures also showed record values in 2015 and 2016. Currently, the Arctic is warming at more than twice the rate of lower latitudes

The genetic architecture of membranous nephropathy and its potential to improve non-invasive diagnosis

Membranous Nephropathy (MN) is a rare autoimmune cause of kidney failure. Here we report a genome-wide association study (GWAS) for primary MN in 3,782 cases and 9,038 controls of East Asian and European ancestries. We discover two previously unreported loci, NFKB1 (rs230540, OR = 1.25, P = 3.4 × 10-12) and IRF4 (rs9405192, OR = 1.29, P = 1.4 × 10-14), fine-map the PLA2R1 locus (rs17831251, OR = 2.25, P = 4.7 × 10-103) and report ancestry-specific effects of three classical HLA alleles: DRB1*1501 in East Asians (OR = 3.81, P = 2.0 × 10-49), DQA1*0501 in Europeans (OR = 2.88, P = 5.7 × 10-93), and DRB1*0301 in both ethnicities (OR = 3.50, P = 9.2 × 10-23 and OR = 3.39, P = 5.2 × 10-82, respectively). GWAS loci explain 32% of disease risk in East Asians and 25% in Europeans, and correctly re-classify 20-37% of the cases in validation cohorts that are antibody-negative by the serum anti-PLA2R ELISA diagnostic test. Our findings highlight an unusual genetic architecture of MN, with four loci and their interactions accounting for nearly one-third of the disease risk

Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders

Funder: Kennedy Trust Rheumatology Research Prize StudentshipFunder: DFG Cluster of Excellence “Precision Medicine in Chronic In-flammation” (PMI; ID: EXC2167)Funder: EC | EC Seventh Framework Programm | FP7 Ideas: European Research Council (FP7-IDEAS-ERC - Specific Programme: “Ideas” Implementing the Seventh Framework Programme of the European Community for Research, Technological Development and Demonstration Activities (2007 to 2013)); doi: https://doi.org/10.13039/100011199; Grant(s): 715772Funder: NWO-VIDI grant 016.178.056, the Netherlands Heart Foundation CVON grant 2018-27, and NWO Gravitation grant ExposomeNLFunder: Li Ka Shing Foundation (Li Ka Shing Foundation Limited); doi: https://doi.org/10.13039/100007421Abstract: Irritable bowel syndrome (IBS) results from disordered brain–gut interactions. Identifying susceptibility genes could highlight the underlying pathophysiological mechanisms. We designed a digestive health questionnaire for UK Biobank and combined identified cases with IBS with independent cohorts. We conducted a genome-wide association study with 53,400 cases and 433,201 controls and replicated significant associations in a 23andMe panel (205,252 cases and 1,384,055 controls). Our study identified and confirmed six genetic susceptibility loci for IBS. Implicated genes included NCAM1, CADM2, PHF2/FAM120A, DOCK9, CKAP2/TPTE2P3 and BAG6. The first four are associated with mood and anxiety disorders, expressed in the nervous system, or both. Mirroring this, we also found strong genome-wide correlation between the risk of IBS and anxiety, neuroticism and depression (rg > 0.5). Additional analyses suggested this arises due to shared pathogenic pathways rather than, for example, anxiety causing abdominal symptoms. Implicated mechanisms require further exploration to help understand the altered brain–gut interactions underlying IBS

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.

Reduced glomerular filtration rate defines chronic kidney disease and is associated with cardiovascular and all-cause mortality. We conducted a meta-analysis of genome-wide association studies for estimated glomerular filtration rate (eGFR), combining data across 133,413 individuals with replication in up to 42,166 individuals. We identify 24 new and confirm 29 previously identified loci. Of these 53 loci, 19 associate with eGFR among individuals with diabetes. Using bioinformatics, we show that identified genes at eGFR loci are enriched for expression in kidney tissues and in pathways relevant for kidney development and transmembrane transporter activity, kidney structure, and regulation of glucose metabolism. Chromatin state mapping and DNase I hypersensitivity analyses across adult tissues demonstrate preferential mapping of associated variants to regulatory regions in kidney but not extra-renal tissues. These findings suggest that genetic determinants of eGFR are mediated largely through direct effects within the kidney and highlight important cell types and biological pathways

Creative Integration and Pragmatist Optimism: Dispositions for “the Task Before Us”

How can and will educators in any setting work with young people of all ages to enable them to develop the ability to interrogate—without denigrating—the claims of candidates, the newsmaking of media, the needs of their neighbors, and the fears of their family members? The answer I offer and defend here involves two dispositions—creative integration and pragmatist optimism—that I view as critical to the pursuit of vibrant and viable political democracy. These dispositions are, I argue, necessary to and evidence of the very possibility of a polity worthy of the democratic label

Stengel, Barbara S., \u27Academic Discipline\u27 and \u27School Subject\u27: Contestable Curriculum Concepts, Journal of Curriculum Studies, 29(September-October, 1997), 585-602.*

Examines five views of the relation between the concepts of academic discipline and of school subject; gives implications for curriculum

Dewey, Women, and Weirdoes: or, the Potential Rewards for Scholars who Dialog across Difference

This symposium provides five case studies of the ways that John Dewey\u27s philosophy and practice were influenced by women or weirdoes (our choices include F.M. Alexander, Albert Barnes, Helen Bradford Thompson, Elsie Riply Clapp, and Jane Addams) and presents some conclusions about the value of dialoging across difference for philosophers and other scholars

Thinking Philosophically About Teaching

O diagnóstico que motivou o programa Pitch.Gov.SP deriva de duas situações problema: a dificuldade de inovação dentro do setor público e o desejo das startups e empresas de tecnologias de oferecerem seus serviços ao governo. O Pitch.Gov.SP é uma ação que busca encontrar soluções inovadoras para desafios de relevância pública em diferentes áreas. O programa aproxima os gestores públicos de soluções desenvolvidas por startups e permite que empreendedores testes seus produtos no ambiente público. O programa busca, a partir de desafios elencados por órgãos públicos, selecionar empresas nascentes que apresentem ferramentas capazes de melhorar a prestação de serviços. Para o gestor, há o contato com empresas e soluções antes desconhecidas e a capacitação em práticas de trabalho inovadoras. Para as empresas nascentes, há a possibilidade de aprimorar os seus produtos, ganhando escala suficiente para oferecer produtos robustos e bem-sucedidos. O programa teve a sua segunda edição lançada em setembro de 2017 e teve como resultado doze soluções sendo recomendadas para testes. Como exemplo, é possível citar a Aquarela, que criou um ranking de preenchimento das bases de nascimentos e óbitos para municípios e entregou produtos finalizados que auxiliaram no desenvolvimento de políticas.20 p.InovaçãoIniciativa premiada no 22º Concurso Inovação no Setor Público sob responsabilidade de Karla Bertocco Trindade, Subsecretária de Parcerias e Inovação. Iniciativas premiadas no 22º Concurso Inovação no Setor Público 2017. Área temática: Inovação em processos organizacionais, serviços ou políticas públicas no Poder Executivo estadual/distrita