Efectividad del ácido hialurónico en el tratamiento de enfermedades degenerativas de la articulación temporomandibular. Revisión de Literatura.

Background: The degenerative diseases of the tempo-romandibular joint (TMJ) are characterized by a progressive destruction of the articular tissues of the condyle and the glenoid fossa. The main aim of this review is to describe the effectiveness of the hyaluronic acid (HA) in the treatment of degenerative diseases of the TMJ in accordance with the available scientific evidence. Material and Methods: A literature search was made in the following databases EBSCO, Pubmed, Cochrane and Trip Database, using the keywords hyaluronic, hyaluronan, NaH, hyaluronate, tmj, tmd, cmd, craniomandibular, orofacial pain and temporomandibular. There were no date or language restrictions applied. Results: After applying inclusion and exclusion criteria, 14 studies were included in this review (11 randomized controlled clinical trials and 3 non-randomized clinical trials). Conclusion: The studies reported a decrease in pain and improvement in functional parameters after treatment of TMJ osteoarthritis with HA. The use of arthrocentesis associated with the administration of HA provides effects synergistic, reaching a superiority the protocols with multiple injections with respect to those of a single session. The adverse effects related to the injection of HA with or without associated arthrocentesis were minor and transitory.Resumen: Objetivo: Las enfermedades degenerativas de la articulación temporomandibular (ATM) se caracterizan por una destrucción progresiva de tejidos articulares en el cóndilo y la fosa glenoidea. El objetivo principal de esta revisión es describir la efectividad del uso de ácido hialurónico en el tratamiento de enfermedades degenerativas de la articulación temporomandibular de acuerdo con la evidencia científica disponible. Material y Métodos: Se realizó una búsqueda de la literatura en las bases de datos electrónicas EBSCO, PubMed, Cochrane y Trip Database, utilizando las palabras claves hyaluronic, hyaluronan, NaH, hyaluronate, tmj, tmd, cmd, craniomandibular, orofacial pain y temporomandibular, sin límite de fecha ni de idioma hasta Mayo del año 2020, complementada con una búsqueda retrógrada. Resultados: Con base en los criterios de inclusión y exclusión, 14 estudios fueron incluidos en esta revisión (11 ensayos clínicos controlados aleatorizados y 3 ensayos clínicos controlados no aleatorizados). Conclusión: Los estudios reportaron una disminución del dolor y mejora en los parámetros funcionales luego del tratamiento de osteoartritis de la ATM con AH. El uso de artrocentesis asociada a la administración del AH provee efectos sinérgicos, alcanzando una superioridad los protocolos con múltiples inyecciones con respecto a aquellos de una sola sesión. Los efectos adversos relacionados con la inyección de AH con o sin artrocentesis asociada fueron menores y transitorios

ANALYSIS OF FUEL CONSUMPTION SENSITIVITY IN FORESTRY ROAD TRANSPORT

The objective of this work was to analyze how the variation of traveled distance, operational speed, journey time and net cargo transported influence the fuel consumption of vehicles in forest road transport. The data were collected in this operation, covering the area between the regions of Campo do Tenente (forest unit) and Piên (industrial unit), in the state of Paraná. We analyzed the partial elements, loaded trip and empty trip, as well as the total transport cycle (loading, unloading and travel). Using the same mechanical tractor, two vehicular compositions were studied, an articulated vehicle (truck tractor + semitrailer + trailer) and a conjugated vehicle (truck tractor + semitrailer). The vehicle telemetric system was used to perform the data collection of travel time, traveled distance, speed average and fuel consumption of the both vehicles. The results showed that the higher fuel consumption occurred in the loaded trips for longer distances. The sensitivity of fuel consumption was mostly influenced by was traveled distance, so it is recommended the use of vehicles of less load capacity for shorter distances

Benefits of Coffee and Therapy for Chronic Pain in Patients Diagnosed with Cancer

El objetivo de este estudio fue determinar mediante una revisión integradora de literatura los beneficios del café y su empleabilidad como terapia para el dolor crónico en pacientes con diagnóstico de cáncer. Materiales y método: Se utilizaron las bases de datos: PubMed, ELSERVIER, Scite, Cochrane Library, Bvs LIbrary, para la adquisición de los artículos y fueron consultadas durante el periodo de marzo de 2021 a mayo de 2022 encontrando 2336 artículos  de los cuales se escogieron 24 que  cumplieron con los criterios de inclusión, a estos artículos se les aplicó la herramienta de evaluación crítica de artículos CASPE según el tipo de articulo, Resultados :  Primero se hizo una caracterización de los estudios encontrando que según el enfoque la mayoría fueron cuantitativos 79% y cualitativos 29%, se categorizaron según nivel de evidencia y grados de recomendación ,  según el país de origen un 32%  fueron realizados en EE. UU , se analizaron las profesiones de los investigadores siendo el grupo más grande con un 17%  por médicos , los hallazgos se agruparon en 5 categorías según los objetivos específicos del estudio : Describir las sustancias protectoras que tienen el café para prevención de cáncer, Identificar el mecanismo de acción de las propiedades del café para el alivio del dolor crónico, Describir los beneficios del café en pacientes con diagnóstico de cáncer , Relacionar la dosis de café requerida para generar un efecto protector para cáncer e inhibitorio del dolor  y Proponer un plan de terapias alternativas con el uso del café para el manejo del dolor en pacientes con cáncer   . Conclusiones: Los beneficios del café van a depender del tipo de fruto, preparación, procesamiento y adición de azúcar u otras sustancias procesadas, contiene múltiples sustancias beneficiosas para la salud  y sus  mayores beneficios se obtienen al consumir la bebida sin azúcar o ninguna otra sustancia añadida, los componentes del café tales como el Cafestol y Kaweol  son las moléculas  a las cuales se les atribuye principalmente  propiedades protectoras antineoplásicas y de aumento de sobrevida en enfermedad metastásica , el contenido de cafeína del café puede ayudar a mejorar el umbral del dolor y tolerancia del calor siempre y cuando las tazas bebidas de éste contenga la dosis de cafeína entre 100-200 mg.The objective of this study was to determine, through an integrative review of the literature, the benefits of coffee and its applicability as a therapy for chronic pain in patients diagnosed with cancer. Materials and method: The following databases were used: PubMed, ELSERVIER, Scite, Cochrane Library, Bvs LIbrary, for the acquisition of the articles and were consulted during the period from March 2021 to May 2022 finding 2336 articles of which 24 were chosen that met the inclusion criteria, to these articles the critical evaluation tool of articles CASPE was applied according to the type of article, Results : First a characterization of the studies was made finding that according to the approach the majority were quantitative 79% and qualitative 29% were categorized according to the level of evidence and degrees of recommendation, according to the country of origin, 32% were carried out in the USA. The findings were grouped into 5 categories according to the specific objectives of the study: To describe the protective substances that coffee has for cancer prevention, To identify the mechanism of action of the properties of coffee for the relief of chronic pain, To describe the benefits of coffee in patients diagnosed with cancer, To relate the dose of coffee required to generate a protective effect for cancer and inhibitory pain, and To propose a plan of alternative therapies with the use of coffee for pain management in cancer patients. Conclusions: The benefits of coffee are going to depend on the type of fruit, preparation, processing and addition of sugar or other processed substances, it contains multiple beneficial substances for health and its greatest benefits are obtained when consuming the beverage without sugar or any other added substance, Coffee components such as Cafestol and Kaweol are the molecules to which are mainly attributed antineoplastic protective properties and increased survival in metastatic disease. The caffeine content of coffee can help to improve the pain threshold and heat tolerance as long as the cups drunk contain a dose of caffeine between 100-200 mg

Modelo de Rede Social Virtual para Inclusão Digital e Social

O rápido avanço da tecnologia na sociedade não só proporciona o auxílio de diversas ferramentas para comunicação e inclusão social, como também cria maior necessidade de presença na mesma, um grande exemplo disso são as redes sociais virtuais que se tornaram parte da rotina de grande parcela da população. Neste contexto, tivemos como objetivo encontrar e apresentar um modelo com interface e usabilidade de forma mais clara, permitindo assim que pessoas com deficiência intelectual se incluam em meios sociais digitais. A metodologia constou da análise das dificuldades, testando a usabilidade de outras redes sociais e posteriormente, a iteração com um modelo de rede social acessível gerada do estudo com um grupo de jovens e adultos deficientes intelectuais, frequentadores de um programa de educação especial. Este estudo, por fim, fornece resultados que comprovam a eficácia de uma interface mais adequada para uso daqueles que não estão acostumados com a quantidade excessiva de informação presente em diversos meios de comunicação hoje em dia

Lack of Exposure to Mycobacterium bovis and Mycobacterium avium subsp. paratuberculosis in Chilean Cervids, and Evidence of a New Mycobacterium-Like Sequence

5 Pág. Centro de Investigación en Sanidad Animal (CISA)Screening of serum and fecal samples from huemul (Hippocamelus bisulcus) and pudu (Pudu puda) from southern Chile for Mycobacterium bovis and Mycobacterium avium paratuberculosis (MAP) found all but four samples Mycobacterium-negative. The positive sequences showed only 92-93% similarity with MAP and were from remote Isla Riesco populations.This work was supported by Asociacion Kauyeken through Fondo Nacional de Desarrollo Regional Project 5961 and the J. M. Kaplan Fund, Buin Zoo, NGO Chiloe Silvestre, Universidad San Sebastian-Sede Puerto Mont and ANID/CONICYT Fondecyt 3160056 and 11181180 (to D.M.-A.), and Estancia Anita BeatrizPeer reviewe

Protocolo para el muestreo, análisis y estudio de la biota portuaria en México

Esta obra constituye una guía de procedimientos a seguir para el muestreo, análisis y estudio de la biota portuaria en México. Como herramienta estandarizada, guía a los usuarios paso a paso, desde la planificación para la toma de muestras en marinas, puertos y áreas naturales protegidas de México, hasta el análisis de la información. Tiene el poder de ser replicada para cualquier filo de invertebrados marinos y para cualquier país costero de Latinoamérica. Cuenta con formatos estandarizados para la elaboración de etiquetas, hojas de campo, llenado de bases de datos, e informes, así como para la elaboración o adecuación de equipo y materiales de campo. A lo largo del procedimiento se presentan cadenas de custodia, que permiten asegurar las acciones de control de las muestras, de la información y de las distintas operaciones

Jet energy measurement with the ATLAS detector in proton-proton collisions at root s=7 TeV

The jet energy scale and its systematic uncertainty are determined for jets measured with the ATLAS detector at the LHC in proton-proton collision data at a centre-of-mass energy of √s = 7TeV corresponding to an integrated luminosity of 38 pb-1. Jets are reconstructed with the anti-kt algorithm with distance parameters R=0. 4 or R=0. 6. Jet energy and angle corrections are determined from Monte Carlo simulations to calibrate jets with transverse momenta pT≥20 GeV and pseudorapidities {pipe}η{pipe}<4. 5. The jet energy systematic uncertainty is estimated using the single isolated hadron response measured in situ and in test-beams, exploiting the transverse momentum balance between central and forward jets in events with dijet topologies and studying systematic variations in Monte Carlo simulations. The jet energy uncertainty is less than 2. 5 % in the central calorimeter region ({pipe}η{pipe}<0. 8) for jets with 60≤pT<800 GeV, and is maximally 14 % for pT<30 GeV in the most forward region 3. 2≤{pipe}η{pipe}<4. 5. The jet energy is validated for jet transverse momenta up to 1 TeV to the level of a few percent using several in situ techniques by comparing a well-known reference such as the recoiling photon pT, the sum of the transverse momenta of tracks associated to the jet, or a system of low-pT jets recoiling against a high-pT jet. More sophisticated jet calibration schemes are presented based on calorimeter cell energy density weighting or hadronic properties of jets, aiming for an improved jet energy resolution and a reduced flavour dependence of the jet response. The systematic uncertainty of the jet energy determined from a combination of in situ techniques is consistent with the one derived from single hadron response measurements over a wide kinematic range. The nominal corrections and uncertainties are derived for isolated jets in an inclusive sample of high-pT jets. Special cases such as event topologies with close-by jets, or selections of samples with an enhanced content of jets originating from light quarks, heavy quarks or gluons are also discussed and the corresponding uncertainties are determined. © 2013 CERN for the benefit of the ATLAS collaboration

Measurement of the inclusive and dijet cross-sections of b-jets in pp collisions at sqrt(s) = 7 TeV with the ATLAS detector

The inclusive and dijet production cross-sections have been measured for jets containing b-hadrons (b-jets) in proton-proton collisions at a centre-of-mass energy of sqrt(s) = 7 TeV, using the ATLAS detector at the LHC. The measurements use data corresponding to an integrated luminosity of 34 pb^-1. The b-jets are identified using either a lifetime-based method, where secondary decay vertices of b-hadrons in jets are reconstructed using information from the tracking detectors, or a muon-based method where the presence of a muon is used to identify semileptonic decays of b-hadrons inside jets. The inclusive b-jet cross-section is measured as a function of transverse momentum in the range 20 < pT < 400 GeV and rapidity in the range |y| < 2.1. The bbbar-dijet cross-section is measured as a function of the dijet invariant mass in the range 110 < m_jj < 760 GeV, the azimuthal angle difference between the two jets and the angular variable chi in two dijet mass regions. The results are compared with next-to-leading-order QCD predictions. Good agreement is observed between the measured cross-sections and the predictions obtained using POWHEG + Pythia. MC@NLO + Herwig shows good agreement with the measured bbbar-dijet cross-section. However, it does not reproduce the measured inclusive cross-section well, particularly for central b-jets with large transverse momenta.Comment: 10 pages plus author list (21 pages total), 8 figures, 1 table, final version published in European Physical Journal

Measurement of the cross-section of high transverse momentum vector bosons reconstructed as single jets and studies of jet substructure in pp collisions at √s = 7 TeV with the ATLAS detector

This paper presents a measurement of the cross-section for high transverse momentum W and Z bosons produced in pp collisions and decaying to all-hadronic final states. The data used in the analysis were recorded by the ATLAS detector at the CERN Large Hadron Collider at a centre-of-mass energy of √s = 7 TeV;{\rm Te}{\rm V}$and correspond to an integrated luminosity of$4.6\;{\rm f}{{{\rm b}}^{-1}}$. The measurement is performed by reconstructing the boosted W or Z bosons in single jets. The reconstructed jet mass is used to identify the W and Z bosons, and a jet substructure method based on energy cluster information in the jet centre-of-mass frame is used to suppress the large multi-jet background. The cross-section for events with a hadronically decaying W or Z boson, with transverse momentum${{p}_{{\rm T}}}\gt 320\;{\rm Ge}{\rm V}$and pseudorapidity$|\eta |\lt 1.9$, is measured to be${{\sigma }_{W+Z}}=8.5\pm 1.7$ pb and is compared to next-to-leading-order calculations. The selected events are further used to study jet grooming techniques