ATRIBUIÇÕES DO ENFERMEIRO NO ACOLHIMENTO COM CLASSIFICAÇÃO DE RISCO NOS SERVIÇOS DE URGÊNCIA E EMERGÊNCIA: UM ESTUDO DE REVISÃO INTEGRATIVA

This study aims to describe the duties of nurses during Welcoming with Risk Classification in urgent and emergency services. The present study is an integrative literature review. The bibliographic survey was carried out between October 10th and November 15th, 2023 in the indexed databases: LILACS, SCIELO and PUBMED, using the descriptors “Risk Classification” AND “Nursing”, which are registered in the DECS and which were defined according to the proposed theme. The inclusion criteria for this study were full original articles available in indexed databases, written in Portuguese, and which were recently published in the last six years. After analysis, reading of the studies and application of the inclusion and exclusion criteria, a quantity of 8 articles were selected to compose this integrative review, as they covered the proposed theme. Data analysis was carried out according to the content analysis technique proposed by Bardin. The selected studies were developed in Caruaru, Fortaleza, in the Center West of Goiás, in the interior of Rio Grande do Sul, in João Pessoa, in Santa Catarina, in the Center West region of the state of São Paulo, and in the interior of Rio de Janeiro. The selected studies were displayed in a data table containing the information: title, author, year, study objective, study methodology, and database. In view of the aforementioned aspects, it was possible to observe that the nurse's duties in risk classification are focused on welcoming, dialogue and building a bond with the user and family members, as well as carrying out anamnesis with assessment of vital signs to identify the level of severity and carry out classification according to the Manchester protocol. Furthermore, these professionals carry out a humanized practice, as they evaluate non-severe patients, inform users about the waiting time for care, and notify cases of infectious diseases.Esse estudo tem como objetivo descrever as atribuições dos enfermeiros durante o Acolhimento com Classificação de Risco nos serviços de urgência e emergência. O presente estudo trata-se de uma revisão de literatura do tipo integrativa. O levantamento bibliográfico foi realizado entre o período de 10 de outubro a 15 de novembro de 2023 nas bases de dados indexadas: LILACS, SCIELO e PUBMED, utilizando os descritores “Classificação de Risco” AND “Enfermagem”, que estão registrados nos DECS e que foram definidos conforme a temática proposta. Os critérios de inclusão desse estudo foram os artigos originais na íntegra disponíveis nas bases de dados indexadas, escritos em língua portuguesa, e que foram publicados recentemente nos últimos seis anos. Após a análise, leitura dos estudos e aplicação dos critérios de inclusão e exclusão, foram selecionados um quantitativo de 8 artigos para compor essa revisão integrativa, visto que esses abrangeram a temática proposta. A análise de dados foi realizada conforme a técnica de análise de conteúdo, proposta por Bardin. Os estudos selecionados foram desenvolvidos em Caruaru, Fortaleza, no Centro Oeste de Goiás, no interior do Rio Grande do Sul, em João Pessoa, em Santa Catarina, na região Centro Oeste do estado de São Paulo, e no interior do Rio de Janeiro. Os estudos selecionados foram expostos em um quadro de dados contendo as informações: título, autor, ano, objetivo do estudo, metodologia do estudo, e base de dados. Tendo em vista os referidos aspectos foi possível observar que as atribuições do enfermeiro na classificação de risco estão voltadas ao acolhimento, diálogo e construção de vínculo com o usuário e os familiares, assim como a realização da anamnese com avaliação dos sinais vitais para identificar o nível de gravidade e realizar a classificação segundo o protocolo de Manchester. Além disso, esses profissionais realizam uma prática humanizada, pois avaliam os pacientes não graves, informam os usuários sobre o tempo de espera para o atendimento, e realizam a notificação dos casos de doenças infectocontagiosas

Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements

Knowledge on oral cancer among dentistry students at Federal University of Maranhão

INTRODUCTION: Oral cancer is a multifactorial disease of high incidence worldwide and considered a public health problem, in which prevention and early diagnosis are the best ways to reverse this situation. PURPOSE: To evaluate the level of knowledge on oral cancer in a population of dentistry students. METHOD: A questionnaire on oral cancer was applied to 150 students from six classes, divided into three groups according to their semesters. The variables studied were statistically analyzed by applying the chi-square test with confidence interval of 95% and significance level of 5%. RESULT: Eighty-eight students (60.61%) considered their level of knowledge on oral cancer good and regular, while 37.93% rated their knowledge as insufficient. Squamous cell carcinoma was listed as the most common cancer by only 38.25% of students, with the highest percentage of correct answers being observed for groups 2 (55.56%) and 3 (67.39%). The level of knowledge on the risk factors increased over the semesters; however, 77.85% considered their level of confidence to perform diagnostic procedures low. CONCLUSION: The level of knowledge on oral cancer was considered good or regular among dentistry students, and although they showed good level of knowledge on the risk factors and to specific issues of the disease, there is a clear need to implement continued educational measures throughout the course to consolidate learning on this disease

Alternatives For Reducing Relapse Rate When Switching From Natalizumab To Fingolimod In Multiple Sclerosis.

Natalizumab is a therapeutic option for treating multiple sclerosis (MS) and is particularly efficacious for patients with highly active disease. A long washout period has been recommended between withdrawal of natalizumab and start of fingolimod (another option for treating MS). This long washout period has been associated with a significant increase in MS activity. In the present study, a group of 96 patients who were switched from natalizumab to fingolimod had short washout periods between drugs, or monthly corticosteroid pulse therapy if longer washout periods were recommended. This therapeutic approach led to the lowest reported relapse rate so far, among patients with MS switching from natalizumab to fingolimod (8.3%). No complications from short withdrawal were observed in this group of patients.

Characteristics and outcomes of an international cohort of 600 000 hospitalized patients with COVID-19

Background: We describe demographic features, treatments and clinical outcomes in the International Severe Acute Respiratory and emerging Infection Consortium (ISARIC) COVID-19 cohort, one of the world's largest international, standardized data sets concerning hospitalized patients. Methods: The data set analysed includes COVID-19 patients hospitalized between January 2020 and January 2022 in 52 countries. We investigated how symptoms on admission, co-morbidities, risk factors and treatments varied by age, sex and other characteristics. We used Cox regression models to investigate associations between demographics, symptoms, co-morbidities and other factors with risk of death, admission to an intensive care unit (ICU) and invasive mechanical ventilation (IMV). Results: Data were available for 689 572 patients with laboratory-confirmed (91.1%) or clinically diagnosed (8.9%) SARS-CoV-2 infection from 52 countries. Age [adjusted hazard ratio per 10 years 1.49 (95% CI 1.48, 1.49)] and male sex [1.23 (1.21, 1.24)] were associated with a higher risk of death. Rates of admission to an ICU and use of IMV increased with age up to age 60 years then dropped. Symptoms, co-morbidities and treatments varied by age and had varied associations with clinical outcomes. The case-fatality ratio varied by country partly due to differences in the clinical characteristics of recruited patients and was on average 21.5%. Conclusions: Age was the strongest determinant of risk of death, with a ∼30-fold difference between the oldest and youngest groups; each of the co-morbidities included was associated with up to an almost 2-fold increase in risk. Smoking and obesity were also associated with a higher risk of death. The size of our international database and the standardized data collection method make this study a comprehensive international description of COVID-19 clinical features. Our findings may inform strategies that involve prioritization of patients hospitalized with COVID-19 who have a higher risk of death

Searches for the ZγZ\gamma decay mode of the Higgs boson and for new high-mass resonances in pppp collisions at s=13\sqrt{s} = 13 TeV with the ATLAS detector

International audienceThis article presents searches for the Zγ decay of the Higgs boson and for narrow high-mass resonances decaying to Zγ, exploiting Z boson decays to pairs of electrons or muons. The data analysis uses 36.1 fb$^{−1}$ of pp collisions at $\sqrt{s}=13$ recorded by the ATLAS detector at the CERN Large Hadron Collider. The data are found to be consistent with the expected Standard Model background. The observed (expected — assuming Standard Model pp → H → Zγ production and decay) upper limit on the production cross section times the branching ratio for pp → H → Zγ is 6.6. (5.2) times the Standard Model prediction at the 95% confidence level for a Higgs boson mass of 125.09 GeV. In addition, upper limits are set on the production cross section times the branching ratio as a function of the mass of a narrow resonance between 250 GeV and 2.4 TeV, assuming spin-0 resonances produced via gluon-gluon fusion, and spin-2 resonances produced via gluon-gluon or quark-antiquark initial states. For high-mass spin-0 resonances, the observed (expected) limits vary between 88 fb (61 fb) and 2.8 fb (2.7 fb) for the mass range from 250 GeV to 2.4 TeV at the 95% confidence level