Resonance fluorescence of a trapped three-level atom

We investigate theoretically the spectrum of resonance fluorescence of a harmonically trapped atom, whose internal transitions are $\Lambda$--shaped and driven at two-photon resonance by a pair of lasers, which cool the center--of--mass motion. For this configuration, photons are scattered only due to the mechanical effects of the quantum interaction between light and atom. We study the spectrum of emission in the final stage of laser--cooling, when the atomic center-of-mass dynamics is quantum mechanical and the size of the wave packet is much smaller than the laser wavelength (Lamb--Dicke limit). We use the spectral decomposition of the Liouville operator of the master equation for the atomic density matrix and apply second order perturbation theory. We find that the spectrum of resonance fluorescence is composed by two narrow sidebands -- the Stokes and anti-Stokes components of the scattered light -- while all other signals are in general orders of magnitude smaller. For very low temperatures, however, the Mollow--type inelastic component of the spectrum becomes visible. This exhibits novel features which allow further insight into the quantum dynamics of the system. We provide a physical model that interprets our results and discuss how one can recover temperature and cooling rate of the atom from the spectrum. The behaviour of the considered system is compared with the resonance fluorescence of a trapped atom whose internal transition consists of two-levels.Comment: 11 pages, 4 Figure

Entanglement transformation at absorbing and amplifying four-port devices

Dielectric four-port devices play an important role in optical quantum information processing. Since for causality reasons the permittivity is a complex function of frequency, dielectrics are typical examples of noisy quantum channels, which cannot preserve quantum coherence. To study the effects of quantum decoherence, we start from the quantized electromagnetic field in an arbitrary Kramers--Kronig dielectric of given complex permittivity and construct the transformation relating the output quantum state to the input quantum state, without placing restrictions on the frequency. We apply the formalism to some typical examples in quantum communication. In particular we show that for entangled qubits the Bell-basis states $|\Psi^\pm>$ are more robust against decoherence than the states $|\Phi^\pm>$.Comment: 12 pages, revtex, 10 eps figures, minor corrections in Appendi

Differential Sulfation Remodelling of Heparan Sulfate by Extracellular 6-O-Sulfatases Regulates Fibroblast Growth Factor-Induced Boundary Formation by Glial Cells: Implications for Glial Cell Transplantation

Previously, it has been shown that rat Schwann cells (SCs), but not olfactory ensheathing cells (OECs), form a boundary with astrocytes, due to a SC-specific secreted factor. Here, we identify highly sulfated heparan sulfates (HSs) and fibroblast growth factors (FGFs) 1 and 9 as possible determinants of boundary formation induced by rat SCs. Disaccharide analysis of HS in SC-conditioned and rat OEC-conditioned media showed that SCs secrete more highly sulfated HS than OECs. The dependence of the boundary-forming activity on high levels of sulfation was confirmed using a panel of semisynthetic modified heparins with variable levels of sulfation. Furthermore, extracellular HS 6-O-endosulfatase enzymes, Sulf 1 and Sulf 2, were expressed at a significantly lower level by SCs compared with OECs, and siRNA reduction of Sulfs in OECs was, in itself, sufficient to induce boundary formation. This demonstrates a key role for remodelling (reduction) of HS 6-O-sulfation by OECs, compared with SCs, to suppress boundary formation. Furthermore, specific anti-FGF1 and anti-FGF9 antibodies disrupted SC–astrocyte boundary formation, supporting a role for an HS sulfation-dependent FGF signaling mechanism via FGF receptors on astrocytes. We propose a model in which FGF1 and FGF9 signaling is differentially modulated by patterns of glial cell HS sulfation, dependent on Sulf 1 and Sulf 2 expression, to control FGF receptor 3-IIIb-mediated astrocytic responses. Moreover, these data suggest manipulation of HS sulfation after CNS injury as a potential novel approach for therapeutic intervention in CNS repair

Quantized Skyrmion Fields in 2+1 Dimensions

A fully quantized field theory is developped for the skyrmion topological excitations of the O(3) symmetric CP$^1$-Nonlinear Sigma Model in 2+1D. The method allows for the obtainment of arbitrary correlation functions of quantum skyrmion fields. The two-point function is evaluated in three different situations: a) the pure theory; b) the case when it is coupled to fermions which are otherwise non-interacting and c) the case when an electromagnetic interaction among the fermions is introduced. The quantum skyrmion mass is explicitly obtained in each case from the large distance behavior of the two-point function and the skyrmion statistics is inferred from an analysis of the phase of this function. The ratio between the quantum and classical skyrmion masses is obtained, confirming the tendency, observed in semiclassical calculations, that quantum effects will decrease the skyrmion mass. A brief discussion of asymptotic skyrmion states, based on the short distance behavior of the two-point function, is also presented.Comment: Accepted for Physical Review

Nonleptonic Weak Decays of Bottom Baryons

Cabibbo-allowed two-body hadronic weak decays of bottom baryons are analyzed. Contrary to the charmed baryon sector, many channels of bottom baryon decays proceed only through the external or internal W-emission diagrams. Moreover, W-exchange is likely to be suppressed in the bottom baryon sector. Consequently, the factorization approach suffices to describe most of the Cabibbo-allowed bottom baryon decays. We use the nonrelativistic quark model to evaluate heavy-to-heavy and heavy-to-light baryon form factors at zero recoil. When applied to the heavy quark limit, the quark model results do satisfy all the constraints imposed by heavy quark symmetry. The decay rates and up-down asymmetries for bottom baryons decaying into $(1/2)^++P(V)$ and $(3/2)^++P(V)$ are calculated. It is found that the up-down asymmetry is negative except for $\Omega_b \to (1/2)^++P(V)$ decay and for decay modes with $\psi'$ in the final state. The prediction $B(\Lambda_b \to J/\psi\Lambda)=1.6 \times 10^{-4}$ for $|V_{cb}|=0.038$ is consistent with the recent CDF measurement. We also present estimates for $\Omega_c \to (3/2)^++P(V)$ decays and compare with various model calculations.Comment: 24 pages, to appear in Phys. Rev. Uncertainties with form factor q^2 dependence are discusse

Study of KS KL Coupled Decays and KL -Be Interactions with the CMD-2 Detector at VEPP-2M Collider

The integrated luminosity about 4000 inverse nanobarn of around phi meson mass ( 5 millions of phi mesons) has been collected with the CMD-2 detector at the VEPP-2M collider. A latest analysis of the KS KL coupled decays based on 30 % of available data is presented in this paper. The KS KL pairs from phi meson decays were reconstructed in the drift chamber when both kaons decayed into two charged particles. From a sample of 1423 coupled decays a selection of candidates to the CP violating KL into pi+ pi- decay was performed. CP violating decays were not identified because of the domination of events with a KL regenerating at the Be beam pipe into KS and a background from KL semileptonic decays. The regeneration cross section of 110 MeV/c KL mesons was found to be 53 +- 17 mb in agreement with theoretical expectations. The angular distribution of KS mesons after regeneration and the total cross section of KL for Be have been measured.Comment: 14 pages, 8 figure

Reconceptualising adaptation to climate change as part of pathways of change and response

The need to adapt to climate change is now widely recognised as evidence of its impacts on social and natural systems grows and greenhouse gas emissions continue unabated. Yet efforts to adapt to climate change, as reported in the literature over the last decade and in selected case studies, have not led to substantial rates of implementation of adaptation actions despite substantial investments in adaptation science. Moreover, implemented actions have been mostly incremental and focused on proximate causes; there are far fewer reports of more systemic or transformative actions. We found that the nature and effectiveness of responses was strongly influenced by framing. Recent decision-oriented approaches that aim to overcome this situation are framed within a "pathways" metaphor to emphasise the need for robust decision making within adaptive processes in the face of uncertainty and inter-temporal complexity. However, to date, such "adaptation pathways" approaches have mostly focused on contexts with clearly identified decision-makers and unambiguous goals; as a result, they generally assume prevailing governance regimes are conducive for adaptation and hence constrain responses to proximate causes of vulnerability. In this paper, we explore a broader conceptualisation of "adaptation pathways" that draws on 'pathways thinking' in the sustainable development domain to consider the implications of path dependency, interactions between adaptation plans, vested interests and global change, and situations where values, interests, or institutions constrain societal responses to change. This re-conceptualisation of adaptation pathways aims to inform decision makers about integrating incremental actions on proximate causes with the transformative aspects of societal change. Case studies illustrate what this might entail. The paper ends with a call for further exploration of theory, methods and procedures to operationalise this broader conceptualisation of adaptation

The origin of fracture in the I-ECAP of AZ31B magnesium alloy

Magnesium alloys are very promising materials for weight-saving structural applications due to their low density, comparing to other metals and alloys currently used. However, they usually suffer from a limited formability at room temperature and low strength. In order to overcome those issues, processes of severe plastic deformation (SPD) can be utilized to improve mechanical properties, but processing parameters need to be selected with care to avoid fracture, very often observed for those alloys during forming. In the current work, the AZ31B magnesium alloy was subjected to SPD by incremental equal-channel angular pressing (I-ECAP) at temperatures varying from 398 K to 525 K (125 °C to 250 °C) to determine the window of allowable processing parameters. The effects of initial grain size and billet rotation scheme on the occurrence of fracture during I-ECAP were investigated. The initial grain size ranged from 1.5 to 40 µm and the I-ECAP routes tested were A, BC, and C. Microstructures of the processed billets were characterized before and after I-ECAP. It was found that a fine-grained and homogenous microstructure was required to avoid fracture at low temperatures. Strain localization arising from a stress relaxation within recrystallized regions, namely twins and fine-grained zones, was shown to be responsible for the generation of microcracks. Based on the I-ECAP experiments and available literature data for ECAP, a power law between the initial grain size and processing conditions, described by a Zener–Hollomon parameter, has been proposed. Finally, processing by various routes at 473 K (200 °C) revealed that route A was less prone to fracture than routes BC and C

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic annotation data along with multi-platform molecular profiles of more than 11,000 human tumors across 33 different cancer types. TCGA clinical data contain key features representing the democratized nature of the data collection process. To ensure proper use of this large clinical dataset associated with genomic features, we developed a standardized dataset named the TCGA Pan-Cancer Clinical Data Resource (TCGA-CDR), which includes four major clinical outcome endpoints. In addition to detailing major challenges and statistical limitations encountered during the effort of integrating the acquired clinical data, we present a summary that includes endpoint usage recommendations for each cancer type. These TCGA-CDR findings appear to be consistent with cancer genomics studies independent of the TCGA effort and provide opportunities for investigating cancer biology using clinical correlates at an unprecedented scale. Analysis of clinicopathologic annotations for over 11,000 cancer patients in the TCGA program leads to the generation of TCGA Clinical Data Resource, which provides recommendations of clinical outcome endpoint usage for 33 cancer types

Search for direct production of charginos and neutralinos in events with three leptons and missing transverse momentum in √s = 7 TeV pp collisions with the ATLAS detector

A search for the direct production of charginos and neutralinos in final states with three electrons or muons and missing transverse momentum is presented. The analysis is based on 4.7 fb−1 of proton–proton collision data delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in three signal regions that are either depleted or enriched in Z-boson decays. Upper limits at 95% confidence level are set in R-parity conserving phenomenological minimal supersymmetric models and in simplified models, significantly extending previous results