An Approach for Efficient Neural Architecture Search Space Definition

As we advance in the fast-growing era of Machine Learning, various new and more complex neural architectures are arising to tackle problem more efficiently. On the one hand their efficient usage requires advanced knowledge and expertise, which is most of the time difficult to find on the labor market. On the other hand, searching for an optimized neural architecture is a time-consuming task when it is performed manually using a trial and error approach. Hence, a method and a tool support is needed to assist users of neural architectures, leading to an eagerness in the field of Automatic Machine Learning (AutoML). When it comes to Deep Learning, an important part of AutoML is the Neural Architecture Search (NAS). In this paper, we propose a novel cell-based hierarchical search space, easy to comprehend and manipulate. The objectives of the proposed approach are to optimize the search-time and to be general enough to handle most of state of the art Convolutional Neural Networks (CNN) architectures.Comment: AAAI-22 Workshop: Learning Network Architecture During Training, Feb 2022, Online, United State

Iridium-Catalyzed Asymmetric Intramolecular Allylic Amidation:Enantioselective Synthesis of Chiral Tetrahydroisoquinolines and Saturated Nitrogen Heterocycles

For the first time iridium catalysis has been used for the synthesis of chiral tetrahydroisoquinolines with excellent yields and high enantioselectivities (see scheme; cod=1,5-cyclooctadiene, DBU=1,8-diazabicyclo[5.4.0]undec-7-ene). These products are important chiral building blocks for the synthesis of biologically active compounds, in particular alkaloids

Flavin-Catalyzed Insertion of Oxygen into Rhenium-Methyl Bonds

Article discussing flavin-catalyzed insertion of oxygen into rhenium-methyl bonds

Methyl Complexes of the Transition Metals

Organometallic chemistry can be considered as a wide area of knowledge that combines concepts of classic organic chemistry, that is, based essentially on carbon, with molecular inorganic chemistry, especially with coordination compounds. Transition-metal methyl complexes probably represent the simplest and most fundamental way to view how these two major areas of chemistry combine and merge into novel species with intriguing features in terms of reactivity, structure, and bonding. Citing more than 500 bibliographic references, this review aims to offer a concise view of recent advances in the field of transition-metal complexes containing M-CH fragments. Taking into account the impressive amount of data that are continuously provided by organometallic chemists in this area, this review is mainly focused on results of the last five years. After a panoramic overview on M-CH compounds of Groups 3 to 11, which includes the most recent landmark findings in this area, two further sections are dedicated to methyl-bridged complexes and reactivity.Ministerio de Ciencia e Innovación Projects CTQ2010–15833, CTQ2013-45011 - P and Consolider - Ingenio 2010 CSD2007 - 00006Junta de Andalucía FQM - 119, Projects P09 - FQM - 5117 and FQM - 2126EU 7th Framework Program, Marie Skłodowska - Curie actions C OFUND – Agreement nº 26722

Enantioselective Rhodium-Catalyzed Addition of Potassium Alkenyltrifluoroborates to Cyclic Imines

Cyclic imines, in which the C[DOUBLE BOND]N bond is constrained in the Z geometry, have been identified as highly effective substrates for enantioselective rhodium-catalyzed additions of potassium alkenyltrifluoroborates. Not only is the alkene in the products a useful functional handle for subsequent manipulations, products containing aryl sulfamates may be employed in nickel-catalyzed Suzuki–Miyaura and Kumada coupling reactions to generate further compounds of interest

DUTCH SPRING : Ouverture de la collection « École Hollandaise », L’aile récemment rénovée de la collection d'art hollandais des MRBAB (Bruxelles)

Voyagez à travers le siècle d'or hollandais et (re)découvrez des artistes tels que Frans Hals, Rembrandt van Rijn, Nicolaes Maes, Abraham Bloemaert, Jan van Goyen, Jacob van Ruisdael ou Pieter de Hooch. L’aile récemment rénovée de l’ « École hollandaise » accueille des portraits, paysages, scènes de genre et natures mortes, et offre un vaste panorama de cette période artistique fascinante. Le XVIIe siècle a apporté aux Pays-Bas du Nord une ère de prospérité économique sans précédent. Pendant ..

Exposition : Sacrée architecture ! La passion d'un collectionneur (Cassel, Musée de Flandre, 15 février - 14 juin 2020)

Une collection n’existe pas sans passion… Sacrée Architecture ! présentera pour la première fois au public une collection à laquelle un homme a consacré plus de quarante années de sa vie. Lui qui rêvait de devenir architecte s’est pris de passion pour les tableaux flamands et hollandais des XVIe et XVIIe siècles représentant des intérieurs d’églises en perspective, véritable défi pour l’artiste ! À la fin du XVIe siècle alors que la controverse entre protestants et catholiques est vive, en ..

Exposition : Nicolas Régnier, l'homme libre (Nantes, jusqu'au 11 mars)

Nicolas Régnier (v. 1588-1667), Le Camouflet. Huile sur toile, H. 1,01 x L. 1,33 m, Stockholm, Nationalmuseum, NM 7077. Première rétrospective mondiale dédiée au peintre Nicolas Régnier, cette exposition fait écho aux collections caravagesques remarquables du musée (Georges de La Tour, Maître de l'Annonce aux bergers, Stom, etc.). À travers une quarantaine de tableaux issus des plus grandes collections publiques et privées internationales, l’exposition retrace les deux grandes périodes de la ..