385 research outputs found
Os efeitos do cigarro e do consumo de café sobre a formação óssea e a integração óssea de implantes de hidroxiapatita
The present study aims to assess the effects of cigarette smoke inhalation and/or coffee consumption on bone formation and osseous integration of a dense hydroxyapatite (DHA) implant in rats. For this study, 20 male rats were divided into four groups (n = 5): CT (control) group, CE (coffee) group, CI (cigarette) group and CC (coffee + cigarette) group. During 16 weeks, animals in the CI group were exposed to cigarette smoke inhalation equivalent to 6 cigarettes per day; specimens in the CE group drank coffee as liquid diet; and rats in the CC group were submitted to both substances. In the 6th week a 5 mm slit in the parietal bone and a 4 mm slit in the tibia were performed on the left side: the former was left open while the latter received a DHA implant. As soon as surgeries were finished, the animals returned to their original protocols and after 10 weeks of exposure they were euthanised (ethically sacrificed) and the mentioned bones collected for histological processing. Data showed that exposure to cigarette smoke inhalation and coffee consumption did not interfere in weight gain and that solid and liquid diet consumption was satisfactory. Rats in the CC group showed a decrease in bone neoformation around the tibial DHA implant (31.8 ± 2.8) as well as in bone formation in the parietal slit (28.6 ± 2.2). On their own, cigarette smoke inhalation or coffee consumption also led to diminished bone neoformation around the implant and delayed the bone repair process in relation to the CT group. However, reduction in the bone repair process was accentuated with exposure to both cigarette smoke inhalation and coffee consumption in this study.O presente estudo teve como objetivo avaliar os efeitos do tabagismo e do consumo de cafĂ©, isolada ou concomitantemente, sobre a formação Ăłssea e a osseointegração de implantes hidroxiapatita densa. Foram utilizados 20 ratos machos, divididos em quatro grupos (n = 5): grupo CT (controle); grupo CA (cafĂ©); grupo CI (cigarro), e grupo CC (cigarro + cafĂ©). Durante 16 semanas, os animais do grupo CI foram expostos Ă fumaça de seis cigarros/dia; os animais do grupo CA consumiram cafĂ© como dieta lĂquida, e os animais do grupo CC, ambas as substĂąncias. ApĂłs seis semanas de exposição, uma falha Ăłssea de 5 mm foi produzida no osso parietal esquerdo e de 4 mm, na tĂbia esquerda dos animais. A falha do parietal foi mantida aberta, enquanto na tĂbia corpos cerĂąmicos de hidroxiapatita densa (HAD) foram implantados em cavidade produzida cirurgicamente. ApĂłs as cirurgias, os animais retornaram aos protocolos experimentais e, ao tĂ©rmino de dez semanas, foram eutanasiados, sendo as tĂbias e os parietais coletados para processamento histolĂłgico. A exposição Ă fumaça do cigarro e o consumo de cafĂ© nĂŁo interferiram no ganho de peso dos animais, e os consumos de dieta lĂquida e sĂłlida foram satisfatĂłrios entre os grupos. Os animais do grupo CC apresentaram menor volume de osso neoformado ao redor do implante de HAD na tĂbia (31,8 ± 2,8) e menor osteogĂȘnese na falha produzida no osso parietal (28,6 ± 2,2). O cafĂ© e o cigarro consumidos isoladamente provocam a diminuição do volume de osso ao redor do implante e o atraso no processo de reparação Ăłssea. Observou-se que o consumo de cafĂ© associado Ă exposição Ă fumaça do cigarro reduziu de forma acentuada o processo de reparação Ăłssea, no presente estudo.17317
Moduli spaces of toric manifolds
We construct a distance on the moduli space of symplectic toric manifolds of
dimension four. Then we study some basic topological properties of this space,
in particular, path-connectedness, compactness, and completeness. The
construction of the distance is related to the Duistermaat-Heckman measure and
the Hausdorff metric. While the moduli space, its topology and metric, may be
constructed in any dimension, the tools we use in the proofs are
four-dimensional, and hence so is our main result.Comment: To appear in Geometriae Dedicata, minor changes to previous version,
19 pages, 6 figure
Os efeitos do cigarro e do consumo de café sobre a formação óssea e a integração óssea de implantes de hidroxiapatita
The present study aims to assess the effects of cigarette smoke inhalation and/or coffee consumption on bone formation and osseous integration of a dense hydroxyapatite (DHA) implant in rats. For this study, 20 male rats were divided into four groups (n = 5): CT (control) group, CE (coffee) group, CI (cigarette) group and CC (coffee + cigarette) group. During 16 weeks, animals in the CI group were exposed to cigarette smoke inhalation equivalent to 6 cigarettes per day; specimens in the CE group drank coffee as liquid diet; and rats in the CC group were submitted to both substances. In the 6th week a 5 mm slit in the parietal bone and a 4 mm slit in the tibia were performed on the left side: the former was left open while the latter received a DHA implant. As soon as surgeries were finished, the animals returned to their original protocols and after 10 weeks of exposure they were euthanised (ethically sacrificed) and the mentioned bones collected for histological processing. Data showed that exposure to cigarette smoke inhalation and coffee consumption did not interfere in weight gain and that solid and liquid diet consumption was satisfactory. Rats in the CC group showed a decrease in bone neoformation around the tibial DHA implant (31.8 ± 2.8) as well as in bone formation in the parietal slit (28.6 ± 2.2). On their own, cigarette smoke inhalation or coffee consumption also led to diminished bone neoformation around the implant and delayed the bone repair process in relation to the CT group. However, reduction in the bone repair process was accentuated with exposure to both cigarette smoke inhalation and coffee consumption in this study.O presente estudo teve como objetivo avaliar os efeitos do tabagismo e do consumo de cafĂ©, isolada ou concomitantemente, sobre a formação Ăłssea e a osseointegração de implantes hidroxiapatita densa. Foram utilizados 20 ratos machos, divididos em quatro grupos (n = 5): grupo CT (controle); grupo CA (cafĂ©); grupo CI (cigarro), e grupo CC (cigarro + cafĂ©). Durante 16 semanas, os animais do grupo CI foram expostos Ă fumaça de seis cigarros/dia; os animais do grupo CA consumiram cafĂ© como dieta lĂquida, e os animais do grupo CC, ambas as substĂąncias. ApĂłs seis semanas de exposição, uma falha Ăłssea de 5 mm foi produzida no osso parietal esquerdo e de 4 mm, na tĂbia esquerda dos animais. A falha do parietal foi mantida aberta, enquanto na tĂbia corpos cerĂąmicos de hidroxiapatita densa (HAD) foram implantados em cavidade produzida cirurgicamente. ApĂłs as cirurgias, os animais retornaram aos protocolos experimentais e, ao tĂ©rmino de dez semanas, foram eutanasiados, sendo as tĂbias e os parietais coletados para processamento histolĂłgico. A exposição Ă fumaça do cigarro e o consumo de cafĂ© nĂŁo interferiram no ganho de peso dos animais, e os consumos de dieta lĂquida e sĂłlida foram satisfatĂłrios entre os grupos. Os animais do grupo CC apresentaram menor volume de osso neoformado ao redor do implante de HAD na tĂbia (31,8 ± 2,8) e menor osteogĂȘnese na falha produzida no osso parietal (28,6 ± 2,2). O cafĂ© e o cigarro consumidos isoladamente provocam a diminuição do volume de osso ao redor do implante e o atraso no processo de reparação Ăłssea. Observou-se que o consumo de cafĂ© associado Ă exposição Ă fumaça do cigarro reduziu de forma acentuada o processo de reparação Ăłssea, no presente estudo.Universidade JosĂ© do RosĂĄrio VellanoUniversidade Federal de SĂŁo Paulo (UNIFESP) Escola Paulista de MedicinaUniversidade Federal de AlfenasUniversidade Estadual de CampinasUniversidade JosĂ© do RosĂĄrio Vellano Faculdade de MedicinaUNIFESP, EPMSciEL
Frequency, course and correlates of alcohol use from adolescence to young adulthood in a Swiss community survey
BACKGROUND: Few studies have analyzed the frequency of alcohol use across time from adolescence to young adulthood and its outcome in young adulthood. A Swiss longitudinal multilevel assessment project using various measures of psychopathology and psychosocial variables allowed for the study of the frequency and correlates of alcohol use so that this developmental trajectory may be better understood. METHOD: Alcohol use was studied by a questionnaire in a cohort of N = 593 subjects who had been assessed at three times between adolescence and young adulthood within the Zurich Psychology and Psychopathology Study (ZAPPS). Other assessment included questionnaire data measuring emotional and behavioural problems, life events, coping style, self-related cognitions, perceived parenting style and school environment, and size and efficiency of the social network. RESULTS: The increase of alcohol use from early adolescence to young adulthood showed only a few sex-specific differences in terms of the amount of alcohol consumption and the motives to drink. In late adolescence and young adulthood, males had a higher amount of alcohol consumption and were more frequently looking for drunkenness and feeling high. Males also experienced more negative consequences of alcohol use. A subgroup of heavy or problem drinkers showed a large range of emotional and behavioural problems and further indicators of impaired psychosocial functioning both in late adolescence and young adulthood. CONCLUSION: This Swiss community survey documents that alcohol use is problematic in a sizeable proportion of youth and goes hand in hand with a large number of psychosocial problems
A Small Mammal Community in a Forest Fragment, Vegetation Corridor and Coffee Matrix System in the Brazilian Atlantic Forest
The objective of our work was to verify the value of the vegetation corridor in the conservation of small mammals in fragmented tropical landscapes, using a model system in the southeastern Minas Gerais. We evaluated and compared the composition and structure of small mammals in a vegetation corridor, forest fragments and a coffee matrix. A total of 15 species were recorded, and the highest species richness was observed in the vegetation corridor (13 species), followed by the forest fragments (10) and the coffee matrix (6). The absolute abundance was similar between the vegetation corridor and fragments (Fâ=â22.94; pâ=â0.064), and the greatest differences occurred between the vegetation corridor and the matrix (Fâ=â22.94; pâ=â0.001) and the forest fragments and the matrix (Fâ=â22.94; pâ=â0.007). Six species showed significant habitat preference possibly related to the sensitivity of the species to the forest disturbance. Marmosops incanus was the species most sensitive to disturbance; Akodon montensis, Cerradomys subflavus, Gracilinanus microtarsus and Rhipidomys sp. displayed little sensitivity to disturbance, with a high relative abundance in the vegetation corridor. Calomys sp. was the species least affected by habitat disturbance, displaying a high relative abundance in the coffee matrix. Although the vegetation corridors are narrow (4 m width), our results support the hypothesis in which they work as a forest extension, share most species with the forest fragment and support species richness and abundance closer to forest fragments than to the coffee matrix. Our work highlights the importance and cost-effectiveness of these corridors to biodiversity management in the fragmented Atlantic Forest landscapes and at the regional level
Search for direct pair production of the top squark in all-hadronic final states in proton-proton collisions at sâ=8 TeV with the ATLAS detector
The results of a search for direct pair production of the scalar partner to the top quark using an integrated luminosity of 20.1fbâ1 of protonâproton collision data at âs = 8 TeV recorded with the ATLAS detector at the LHC are reported. The top squark is assumed to decay via tËâtÏË01 or tËâ bÏ˱1 âbW(â)ÏË01 , where ÏË01 (Ï˱1 ) denotes the lightest neutralino (chargino) in supersymmetric models. The search targets a fully-hadronic final state in events with four or more jets and large missing transverse momentum. No significant excess over the Standard Model background prediction is observed, and exclusion limits are reported in terms of the top squark and neutralino masses and as a function of the branching fraction of tË â tÏË01 . For a branching fraction of 100%, top squark masses in the range 270â645 GeV are excluded for ÏË01 masses below 30 GeV. For a branching fraction of 50% to either tË â tÏË01 or tË â bÏ˱1 , and assuming the Ï˱1 mass to be twice the ÏË01 mass, top squark masses in the range 250â550 GeV are excluded for ÏË01 masses below 60 GeV
Search for pair-produced long-lived neutral particles decaying to jets in the ATLAS hadronic calorimeter in ppcollisions at âs=8TeV
The ATLAS detector at the Large Hadron Collider at CERN is used to search for the decay of a scalar boson to a pair of long-lived particles, neutral under the Standard Model gauge group, in 20.3fbâ1of data collected in protonâproton collisions at âs=8TeV. This search is sensitive to long-lived particles that decay to Standard Model particles producing jets at the outer edge of the ATLAS electromagnetic calorimeter or inside the hadronic calorimeter. No significant excess of events is observed. Limits are reported on the product of the scalar boson production cross section times branching ratio into long-lived neutral particles as a function of the proper lifetime of the particles. Limits are reported for boson masses from 100 GeVto 900 GeV, and a long-lived neutral particle mass from 10 GeVto 150 GeV
Plasma level of LDL-cholesterol at diagnosis is a predictor factor of breast tumor progression
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