Contrato de Construccion de Obra Publica

74 p.A través de esta memoria queremos hacer referencia , de manera eminentemente teórica, de una de las figuras contractuales más importantes y eficaces de que dispone el Estado, como órgano administrativo, para cumplir con su finalidad: que es satisfacer las necesidad públicas, y en este caso nos estamos refiriendo al Contrato de Construcción de Obras Públicas. Lo que nos llevó a abordar este tema, es poder observar que la Administración cuenta con las herramientas necesarias para poder otorgar una mejor calidad de vida de la ciudadanía y una adecuada prestación de los servicios, lo que en alguna medida se logra a través de servicios públicos que cuenten con infraestructura de calidad. Por otro lado, dejar atrás el mal concepto y visión que se tiene de este tipo de contratos , debiendo tener presente que para la celebración de este tipo de contratos está sujeto a un cuerpo reglamentario y no al azar

Cholesterol lowering depletes atherosclerotic lesions of smooth muscle cell-derived fibromyocytes and chondromyocytes

S

Human DNA methylomes of neurodegenerative diseases show common epigenomic patterns

Different neurodegenerative disorders often show similar lesions, such as the presence of amyloid plaques, TAU-neurotangles and synuclein inclusions. The genetically inherited forms are rare, so we wondered whether shared epigenetic aberrations, such as those affecting DNA methylation, might also exist. The studied samples were gray matter samples from the prefrontal cortex of control and neurodegenerative disease-associated cases. We performed the DNA methylation analyses of Alzheimer's disease, dementia with Lewy bodies, Parkinson's disease and Alzheimer-like neurodegenerative profile associated with Down's syndrome samples. The DNA methylation landscapes obtained show that neurodegenerative diseases share similar aberrant CpG methylation shifts targeting a defined gene set. Our findings suggest that neurodegenerative disorders might have similar pathogenetic mechanisms that subsequently evolve into different clinical entities. The identified aberrant DNA methylation changes can be used as biomarkers of the disorders and as potential new targets for the development of new therapies

Experiencias de gamificación en aulas

Experiencias de gamificación en aulas / Contreras Espinosa, Ruth S.; Eguia, José Luis -- Gamificación en escenarios educativos. Revisando literatura para aclarar conceptos / Contreras Espinosa, Ruth S. -- Gamificación con PBL para una signatura del grado de Maestro de Educación Infantil / Revuelta Domínguez, Francisco Ignacio; Guerra Antequera, Jorge; Pedrera Rodríguez, Inmaculada -- Del Storytelling al Storylearning. Como motivar a los alumnos de guión y diseño multimedia / Legerén Lago, Beatriz -- Aprendizaje y motivación de la semiótica aplicada. Gamificación con base en la prueba piloto de la plataforma "Aprendiz" / Lugo, Nohemí; Alcántara, Alejandro -- Ethos files : un juego de rol para el área de "valores éticos" / Rubio Méndez, María -- Reader Wars : motivar a los alumnos por la lectura / Paula, Oscar de -- Evaluación y rediseño de una experiencia de gamificación en el aula basada en estilos de aprendizaje y tipos de jugador / Baldeón, Johan; Rodríguez, Inmaculada; Puig, Anna; Lopez-Sanchez, Maite -- Aprender a diseñar diseñando y jugando Serious Games en las aulas / Morales Moras, JoanEste libro pretende reunir experiencias e ideas de un grupo de profesores y expertos en distintos espacios educativos. Además, tiene como intento, anclar el concepto “gamificación” en el creciente cuerpo de literatura sobre esta área y demostrar ejemplos prácticos en asignaturas reales. La gamificación se refiere a un proceso de mejora, con posibilidades para proporcionar experiencias de juego y con el fin de apoyar a las actividades que desarrollan los usuarios. Las definiciones que se han descrito al inicio de la presentación, se han basado en la noción de que la gamificación procede del uso de elementos de diseño de juegos. Sin embargo, no parece haber un conjunto de elementos de juego claramente definidos, es decir, elementos que son estrictamente exclusivos de los juegos pero que no dan lugar automáticamente a experiencias de juego. La gamificación no siempre se lleva a cabo solo a través de elementos concretos. Por lo tanto, se cree que basar estas definiciones en un conjunto de mecanismos es un tema que puede causar confusión. En su lugar, propone que la gamificación podría entenderse de una forma mucho más amplia, y como un proceso en el que el “gamificador” intenta aumentar las probabilidades de la aparición de diferentes experiencias de juego al contagiar posibilidades para ese fin (ya sea mediante distintivos, puntos, etc.)

Experiencias de gamificación en aulas

Experiencias de gamificación en aulas / Contreras Espinosa, Ruth S.; Eguia, José Luis -- Gamificación en escenarios educativos. Revisando literatura para aclarar conceptos / Contreras Espinosa, Ruth S. -- Gamificación con PBL para una signatura del grado de Maestro de Educación Infantil / Revuelta Domínguez, Francisco Ignacio; Guerra Antequera, Jorge; Pedrera Rodríguez, Inmaculada -- Del Storytelling al Storylearning. Como motivar a los alumnos de guión y diseño multimedia / Legerén Lago, Beatriz -- Aprendizaje y motivación de la semiótica aplicada. Gamificación con base en la prueba piloto de la plataforma "Aprendiz" / Lugo, Nohemí; Alcántara, Alejandro -- Ethos files : un juego de rol para el área de "valores éticos" / Rubio Méndez, María -- Reader Wars : motivar a los alumnos por la lectura / Paula, Oscar de -- Evaluación y rediseño de una experiencia de gamificación en el aula basada en estilos de aprendizaje y tipos de jugador / Baldeón, Johan; Rodríguez, Inmaculada; Puig, Anna; Lopez-Sanchez, Maite -- Aprender a diseñar diseñando y jugando Serious Games en las aulas / Morales Moras, JoanEste libro pretende reunir experiencias e ideas de un grupo de profesores y expertos en distintos espacios educativos. Además, tiene como intento, anclar el concepto “gamificación” en el creciente cuerpo de literatura sobre esta área y demostrar ejemplos prácticos en asignaturas reales. La gamificación se refiere a un proceso de mejora, con posibilidades para proporcionar experiencias de juego y con el fin de apoyar a las actividades que desarrollan los usuarios. Las definiciones que se han descrito al inicio de la presentación, se han basado en la noción de que la gamificación procede del uso de elementos de diseño de juegos. Sin embargo, no parece haber un conjunto de elementos de juego claramente definidos, es decir, elementos que son estrictamente exclusivos de los juegos pero que no dan lugar automáticamente a experiencias de juego. La gamificación no siempre se lleva a cabo solo a través de elementos concretos. Por lo tanto, se cree que basar estas definiciones en un conjunto de mecanismos es un tema que puede causar confusión. En su lugar, propone que la gamificación podría entenderse de una forma mucho más amplia, y como un proceso en el que el “gamificador” intenta aumentar las probabilidades de la aparición de diferentes experiencias de juego al contagiar posibilidades para ese fin (ya sea mediante distintivos, puntos, etc.)

The Research Journey as a Challenge Towards New Trends

The academic community of the department of Risaralda, in its permanent interest in evidencing the results of the research processes that are carried out from the Higher Education Institutions and as a product of the VI meeting of researchers of the department of Risaralda held in November 2021 presents its work: “The journey of research as a challenge towards new trends”, which reflects the result of the latest research and advances in different lines of knowledge in Agricultural Sciences, Health Sciences, Social Sciences and Technology and Information Sciences, which seek to solve and meet the demands of the different sectors. This work would not have been possible without the help of each of the teachers, researchers and authors who presented their articles that make up each of the chapters of the book, to them our gratitude for their commitment, dedication and commitment, since their sole purpose is to contribute from the academy and science to scientific and technological development in the search for the solution of problems and thus contribute to transform the reality of our society and communities. We also wish to extend our gratitude to the institutions of the Network that made this publication possible: UTP, UCP, UNAD, UNIREMINGTON; UNISARC, CIAF, Universidad Libre, Uniclaretiana, Fundación Universitaria Comfamiliar and UNIMINUTO, institutions that in one way or another allowed this work to become a reality, which we hope will be of interest to you.Preface............................................................................................................................7 Chapter 1. Technologies and Engineering Towards a humanization in Engineering using soft skills in training in Engineers.............................................................................................................11 Omar Iván Trejos Buriticá1, Luis Eduardo Muñoz Guerrero Innovative materials in construction: review from a bibliometric analysis....................................................................................................................27 Cristian Osorio Gómez, Daniel Aristizábal Torres, Alejandro Alzate Buitrago, Cristhian Camilo Amariles López Bibliometric review of disaster risk management: progress, trends, and challenges.........................................................................................................51 Alejandro Alzate Buitrago, Gloria Milena Molina Vinasco. Incidence of land coverage and geology, in the unstability of lands of the micro-basin of the Combia creek, Pereira, Risaralda....................................73 Alejandro Alzate Buitrago, Daniel Aristizábal Torres. Chapter 2. Arts, Humanities, and Social Sciences Training experience with teachers teaching mathematics using the inquiry methodology ...............................................................................................95 Vivian Libeth Uzuriaga López, Héctor Gerardo Sánchez Bedoya. Interpretation of the multiple representations of the fears associated to the boarding of limited visual patients in the elective I students’ written productions and low vision ...................................................................................113 Eliana Bermúdez Cardona, Ana María Agudelo Guevara, Caterine Villamarín Acosta. The relevance of local knowledge in social sciences............................................131 Alberto Antonio Berón Ospina, Isabel Cristina Castillo Quintero. Basic education students’ conceptions of conflict a view from the peace for the education....................................................................................................143 Astrid Milena Calderón Cárdenas,Carolina Aguirre Arias, Carolina Franco Ossa, Martha Cecilia Gutiérrez Giraldo, Orfa Buitrago. Comprehensive risk prevention in educational settings: an interdisciplinary and socio-educational approach ............................................................................163 Olga María Henao Trujillo, Claudia María López Ortiz. Chapter 3. Natural and Agricultural Sciences Physicochemical characterization of three substrates used in the deep bedding system in swine .......................................................................................175 Juan Manuel Sánchez Rubio, Andrés Felipe Arias Roldan, Jesús Arturo Rincón Sanz, Jaime Andrés Betancourt Vásquez. Periodic solutions in AFM models........................................................................187 Daniel Cortés Zapata, Alexander Gutiérrez Gutiérrez. Phenology in flower and fruit of Rubus glaucus benth. Cv. Thornless in Risaralda: elements for phytosanitary management .........................................199 Shirley Palacios Castro, Andrés Alfonso Patiño Martínez, James Montoya Lerma, Ricardo Flórez, Harry Josué Pérez. Socio-economic and technical characterization of the cultivation of avocado (Persea americana) in Risaralda..............................................................217 Andrés Alfonso Patiño Martínez, Kelly Saudith Castañez Poveda, Eliana Gómez Correa. Biosecurity management in backyard systems in Santa Rosa de Cabal, Risaralda................................................................................................................227 Julia Victoria Arredondo Botero, Jaiver Estiben Ocampo Jaramillo, Juan Sebastián Mera Vallejo, Álvaro de Jesús Aranzazu Hernández. CONTENTS Physical-chemical diagnosis of soils in hillside areas with predominance of Lulo CV. La Selva production system in the department of Risaralda.............241 Adriana Patricia Restrepo Gallón, María Paula Landinez Montes, Jimena Tobón López. Digestibility of three concentrates used in canine feeding....................................271 María Fernanda Mejía Silva, Valentina Noreña Sánchez, Gastón Adolfo Castaño Jiménez. Chapter 4. Economic, Administrative, and Accounting Sciences Financial inclusion in households from socioeconomic strata 1 and 2 in the city of Pereira ..................................................................................................285 Lindy Neth Perea Mosquera, Marlen Isabel Redondo Ramírez, Angélica Viviana Morales. Internal marketing strategies as a competitive advantage for the company Mobilautos SAS de Dosquebradas........................................................................303 Inés Montoya Sánchez, Sandra Patricia Viana Bolaños, Ana María Barrera Rodríguez. Uses of tourist marketing in the tourist sector of the municipality of Belén de Umbría, Risaralda.............................................................................................319 Ana María Barrera Rodríguez, Paola Andrea Echeverri Gutiérrez, María Camila Parra Buitrago, Paola Andrea Martín Muñoz, Angy Paola Ángel Vélez, Luisa Natalia Trejos Ospina. Territorial prospective of Risaralda department (Colombia), based on the SDGS...............................................................................................................333 Juan Guillermo Gil García, Samanta Londoño Velásquez. Chapter 5. Health and Sports Sciences Performance evaluation in times of pandemic. What do medical students think?.......................................................................................................353 Samuel Eduardo Trujillo Henao, Rodolfo A. Cabrales Vega, Germán Alberto Moreno Gómez. The relevance of the therapist’s self and self-reference in the training of psychologists.....................................................................................................371 Maria Paula Marmolejo Lozano, Mireya Ospina Botero. Habits related to oral health which influence lifestyle of elder people in a wellness center for the elderly in Pereira 2020. .............................................387 Isadora Blanco Pérez, Olga Patricia Ramírez Rodríguez, Ángela María Rincón Hurtado. Analysis of the suicide trend in the Coffee Region in Colombia during the years 2012-2018 ..............................................................................................405 Germán Alberto Moreno Gómez, Jennifer Nessim Salazar, Jairo Franco Londoño, Juan Carlos Medina Osorio. Hind limb long bone fractures in canines and felines...........................................419 María Camila Cruz Vélez, Valentina Herrera Morales, Alba Nydia Restrepo Jiménez, Lina Marcela Palomino, Gabriel Rodolfo Izquierdo Bravo. Prevalence of overweight and obesity in children in the rural and urban area of Risaralda....................................................................................................439 Angela María Álvarez López, Angela Liceth Pérez Rendón, Alejandro Gómez Rodas, Luis Enrique Isaza Velásquez. Chapter 6. Architecture, Design and Advertising The artisan crafts of Risaralda, characteristics, importance, and risks within the Colombian Coffee Cultural Landscape, CCCL....................................457 Yaffa Nahir Ivette Gómez Barrera, Javier Alfonso López Morales

Comparison of seven prognostic tools to identify low-risk pulmonary embolism in patients aged <50 years

publishersversionPeer reviewe

The evolution of the ventilatory ratio is a prognostic factor in mechanically ventilated COVID-19 ARDS patients

Background: Mortality due to COVID-19 is high, especially in patients requiring mechanical ventilation. The purpose of the study is to investigate associations between mortality and variables measured during the first three days of mechanical ventilation in patients with COVID-19 intubated at ICU admission. Methods: Multicenter, observational, cohort study includes consecutive patients with COVID-19 admitted to 44 Spanish ICUs between February 25 and July 31, 2020, who required intubation at ICU admission and mechanical ventilation for more than three days. We collected demographic and clinical data prior to admission; information about clinical evolution at days 1 and 3 of mechanical ventilation; and outcomes. Results: Of the 2,095 patients with COVID-19 admitted to the ICU, 1,118 (53.3%) were intubated at day 1 and remained under mechanical ventilation at day three. From days 1 to 3, PaO2/FiO2 increased from 115.6 [80.0-171.2] to 180.0 [135.4-227.9] mmHg and the ventilatory ratio from 1.73 [1.33-2.25] to 1.96 [1.61-2.40]. In-hospital mortality was 38.7%. A higher increase between ICU admission and day 3 in the ventilatory ratio (OR 1.04 [CI 1.01-1.07], p = 0.030) and creatinine levels (OR 1.05 [CI 1.01-1.09], p = 0.005) and a lower increase in platelet counts (OR 0.96 [CI 0.93-1.00], p = 0.037) were independently associated with a higher risk of death. No association between mortality and the PaO2/FiO2 variation was observed (OR 0.99 [CI 0.95 to 1.02], p = 0.47). Conclusions: Higher ventilatory ratio and its increase at day 3 is associated with mortality in patients with COVID-19 receiving mechanical ventilation at ICU admission. No association was found in the PaO2/FiO2 variation

Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study

Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings: This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 81·7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28–2·40], p\textless0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65–3·22], p\textless0·0001), American Society of Anesthesiologists grades 3–5 versus grades 1–2 (2·35 [1·57–3·53], p\textless0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01–2·39], p=0·046), emergency versus elective surgery (1·67 [1·06–2·63], p=0·026), and major versus minor surgery (1·52 [1·01–2·31], p=0·047). Interpretation: Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding: National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research

A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)

Meeting abstrac