48 research outputs found
Defining Kawasaki disease and pediatric inflammatory multisystem syndrome-temporally associated to SARS-CoV-2 infection during SARS-CoV-2 epidemic in Italy: results from a national, multicenter survey
- Author
- 00165 Rome
- Achille Marino: Department of Pediatrics
- Adele Civino: U. O. C. Pediatria P. O. Vito Fazzi Lecce
- Agostina Marolda: Pediatrics and Neonatology Dipartment
- Alessandra Lazzerotti: Clinica Pediatrica
- Alessandra Manerba: Child Cardiology
- Alessandria Italy
- Alice Dell’Anna: U. O. C. Pediatria P. O. Vito Fazzi Lecce
- Alma Olivieri: Dipartimento della donna
- Ancona Italy
- Andrea Campana: Bambino Gesù Children’s Hospital
- Angela Mauro: Department of Paediatrics
- Angela Miniaci: Clinica Pediatrica
- AO SS Antonio e Biago e C. Arrigo
- AORN “Sant’Anna e San Sebastiano”- Caserta
- AOU Meyer
- ASL Romagna
- ASST Bergamo-EST
- ASST FBF Sacco
- ASST Grande Ospedale Metropolitano Niguarda
- ASST Grande Ospedale Metropolitano Niguarda
- ASST Lodi
- ASST Monza
- ASST Ovest Milanese
- ASST Spedali Civili di Brescia and University of Brescia
- ASST Spedali Civili di Brescia e Università degli Studi di Brescia
- Azienda Ospedaliero-Universitaria di Bologna
- Barbara Teruzzi: Maternal and Child Health
- Bari Italy
- Bergamo Italy
- Bergamo Italy
- Bianca Lattanzi: SOD Pediatria
- Bologna Italy
- Bologna Italy
- Bracaglia C
- Brescia Italy
- Brescia Italy
- Cagliari Italy
- Caorsi R
- Cattalini M
- Children’s Hospital V Buzzi
- Cimaz R
- Claudia Santagati: Dipartimento di Pediatria
- Clinica Pediatrica
- Clotilde Alizzi: Department of Health Promotion Sciences Maternal and Infantile Care
- Consolaro A
- del bambino e di chirurgia generale e specialistica
- Della Paolera S
- Dellepiane RM
- Department of Pediatrics
- Department of Woman’s and Child’s Health
- Desio Hospital
- Desio Italy
- Dipartimento della Salute della Donna e del Bambin
- Division of Paediatrics
- Division of Paediatrics
- Domenico Sperlì: UOC di Pediatria S. O. “Annunziata” - A. O. di Cosenza
- Donato Rigante: Department of Pediatrics
- Eleonora Dei Rossi: University of Trieste
- Elpidio Tierno: UOC di Pediatria
- Emanuela Del Giudice: Department of Maternal Infantile and Urological Sciences
- Emergency Department
- Enrico Felici: Pediatric and Pediatric Emergency Unit
- Fabi M
- Florence
- Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico
- Fondazione IRCCS Policlinico San Matteo
- Fondazione MBBM - onlus c/o Ospedale San Gerardo
- Francesca Biscaro: UOC Pediatria
- Francesca Minoia: Fondazione IRCCS Cà Granda
- Francesca Ricci
- Francesco Licciardi: Department of Pediatrics and Public Health
- Giangreco M
- Gianluca Vergine
- Giorgia Martini
- Giovanni Conti: Nefrologia e Reumatologia Pediatrica con Dialisi Azienda Ospedaliero-Universitario “G. Martino”
- Giovanni Filocamo: Fondazione IRCCS Cà Granda
- Grazia Bossi: UOC Pediatria
- Gubbio-Gualdo Tadino Italy
- Guido Pennoni: Dipartimento Materno-Infantile
- Hospital Papa Giovanni XXIII
- Hospital Papa Giovanni XXIII
- Ilenia Floretta: Pediatria
- Internal Medicine and Medical Specialities “G. D’Alessandro”
- IRCCS S. Orsola-Malpighi Hospital
- IRCCS S. Orsola-Malpighi Hospital
- Italy
- Italy. Angelo Mazza: Paediatric Department
- Italy. Maria Vincenza Mastrolia: Pediatric Rheumatology Unit
- La Torre F
- Laura Martelli: Paediatric Department
- Lodi
- Lucia Augusta Baselli: Pediatric Intermediate Care Unit
- Macerata
- Magenta Milan
- Maggio MC
- Maia De Luca: Bambino Gesù Children’s Hospital
- Manzoni Lecco
- Marcello Lanari: Department of Pediatrics
- Marche-Nord
- Marchesi A
- Maria Loreta Foschini: SC Pediatria
- Martina Soliani: Pediatria ASST Cremona Italy
- Matilde Rossi: UOC di Pediatrai e Neonatologia
- Maurizio Carone: UO Malattie Infettive
- Meini A
- Meneghel A
- Milan Italy
- Milan Italy
- Milano
- Milano
- Milano Italy
- Milano Italy
- Montin D
- Monza Italy
- Naples
- Napoli
- Ospedale A
- Ospedale Ca’ Foncello
- Ospedale di Macerata
- Ospedale di Rovigo
- Ospedale Infermi
- Ospedale Maggiore Policlinico
- Ospedale Maggiore Policlinico
- Ospedale Pediatrico ‘Giovanni XXIII’
- Ospedale Santa Chiara
- Ospedali Riuniti
- Padua Italy
- Palermo Italy
- Patrizia Barone: Unità Operativa Complessa di Broncopneumologia Pediatrica AOU “Policlinico - Vittorio Emanuele Via Santa Sofia 78 Catania
- Pavia Italy
- Pediatria
- Piazza S. Onofrio n. 4
- Piero Valentini
- PO SAN MICHELE AOBrotzu
- Polo Pontini
- Ravelli A
- Reumatologia
- Rimini Italy.
- Rome Italy
- Rome Italy
- Rome Italy
- Rome Italy
- Rome Italy
- Rossana Pignataro: UOC Pediatria e Neonatologia
- Rovigo
- Santobono-Pausilipon Children’s Hospital
- Sapeinza University of Rome
- Sara Stucchi: Maternal and Child Health
- Savina Mannarino: Division of Cardiology
- Seriate Bergamo
- Silvia Sonego: University of Trieste
- Simonini G
- Sottile R
- Taddio A Maria Concetta Alberelli: UOC Pediatria
- Tatiana Utytatnikova: Dipartimento Materno-Infantile
- The Children Hospital
- Trento Italy
- Treviso
- Trieste Italy
- Trieste Italy
- Turin Italy
- Univarsità Cattolica Sacro Cuore
- Univarsità Cattolica Sacro Cuore
- University of Bologna
- University of Florence
- University of Padova
- University of Palermo
- University of Turin
- Università della Campania
- Università Milano Bicocca
- UOC Pediatria Rimini
- Verdoni L
- Veronica Bennato: U. O. Pediatria
- Villani A
- Zuccotti G
- Zunica F
- “G. Fornaroli” Hospital
- “L Vanvitelli
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2021
- Field of study
Background: There is mounting evidence on the existence of a Pediatric Inflammatory Multisystem Syndrome-temporally associated to SARS-CoV-2 infection (PIMS-TS), sharing similarities with Kawasaki Disease (KD). The main outcome of the study were to better characterize the clinical features and the treatment response of PIMS-TS and to explore its relationship with KD determining whether KD and PIMS are two distinct entities.
Methods: The Rheumatology Study Group of the Italian Pediatric Society launched a survey to enroll patients diagnosed with KD (Kawasaki Disease Group - KDG) or KD-like (Kawacovid Group - KCG) disease between February 1st 2020, and May 31st 2020. Demographic, clinical, laboratory data, treatment information, and patients' outcome were collected in an online anonymized database (RedCAP®). Relationship between clinical presentation and SARS-CoV-2 infection was also taken into account. Moreover, clinical characteristics of KDG during SARS-CoV-2 epidemic (KDG-CoV2) were compared to Kawasaki Disease patients (KDG-Historical) seen in three different Italian tertiary pediatric hospitals (Institute for Maternal and Child Health, IRCCS "Burlo Garofolo", Trieste; AOU Meyer, Florence; IRCCS Istituto Giannina Gaslini, Genoa) from January 1st 2000 to December 31st 2019. Chi square test or exact Fisher test and non-parametric Wilcoxon Mann-Whitney test were used to study differences between two groups.
Results: One-hundred-forty-nine cases were enrolled, (96 KDG and 53 KCG). KCG children were significantly older and presented more frequently from gastrointestinal and respiratory involvement. Cardiac involvement was more common in KCG, with 60,4% of patients with myocarditis. 37,8% of patients among KCG presented hypotension/non-cardiogenic shock. Coronary artery abnormalities (CAA) were more common in the KDG. The risk of ICU admission were higher in KCG. Lymphopenia, higher CRP levels, elevated ferritin and troponin-T characterized KCG. KDG received more frequently immunoglobulins (IVIG) and acetylsalicylic acid (ASA) (81,3% vs 66%; p = 0.04 and 71,9% vs 43,4%; p = 0.001 respectively) as KCG more often received glucocorticoids (56,6% vs 14,6%; p < 0.0001). SARS-CoV-2 assay more often resulted positive in KCG than in KDG (75,5% vs 20%; p < 0.0001). Short-term follow data showed minor complications. Comparing KDG with a KD-Historical Italian cohort (598 patients), no statistical difference was found in terms of clinical manifestations and laboratory data.
Conclusion: Our study suggests that SARS-CoV-2 infection might determine two distinct inflammatory diseases in children: KD and PIMS-TS. Older age at onset and clinical peculiarities like the occurrence of myocarditis characterize this multi-inflammatory syndrome. Our patients had an optimal response to treatments and a good outcome, with few complications and no deaths
Clinical features and outcomes of elderly hospitalised patients with chronic obstructive pulmonary disease, heart failure or both
- Author
- 13 Francesca Giulia Leoni
- Agostino Gaudio
- Alberto Balle- strero
- Alberto Palazzuoli (Azienda Ospedaliera Università Senese
- Alberto Pilotto
- Alberto Zucchelli (Unità Operativa Complessa di Medicina I a indirizzo geriatrico
- Aleandra Scozzafava
- Ales- sandra Grossi
- Ales- sio Molfino
- Alessandra Bettiol
- Alessandra Bonfanti
- Alessandra Danuta Di Mauro
- Alessandra Danuto Di Mauro
- Alessandra Marengoni
- Alessandro Delitala (Azienda ospedaliera- universitaria di Sassari
- Alessandro Squizzato
- Alessandro Vignali (Azienda Ospe- daliera Universitaria di Parma
- Alessia Giotta
- Alessia Valentina Giraudo
- Alessio Bragagni
- Alessio Comitangelo
- Alessio Greco
- Alfio Gennaro
- Alfredo De Giorgi
- Alice Valoriani
- Allergologia ed Immunologia Clinica)
- Andrea Artoni
- Andrea Falcetta
- Andrea Maresca
- Andrea Piazzoli
- Andrea Salvi
- Andrea Schilardi
- Andrea Ticinesi
- Andrea Volpini
- Angela Sciacqua
- Angelo Rizzo (Azienda Ospe- daliera Universitaria Policlinico Paolo Giaccone
- Angelo Simili
- Angelo Simili (Azienda Ospe- daliera Universitaria Policlinico S. Orsola-Malpighi
- Angiologia Malattie da Arteriosclerosi)
- Anna Dal Col (Azienda Ospedaliera Università San Martino
- Anna L. Fracanzani
- Anna Licata
- Annalisa Cespiati
- Annalisa Pirozzi
- Antonella Afeltra
- Antonella Giorgi
- Antonino Cata- lano
- Antonino Di Pino
- Antonino Di Pino (Ospedale GaribaldiNesima – Catania
- Antonio Brucato
- Antonio Di Sabatino
- Antonio Nouvenne (Azienda Ospedaliera Universitaria di Parma
- Antonio Picardi
- ASL TO4
- Azienda Ospedaliera Universitaria- Ospedali Riuniti di Ancona)
- Azienda Ospedaliera Università San Martino di Genova)
- Azienda Ospedaliero-Universitaria di Cagliari
- Azienda Ospedaliero-Universitaria di Modena
- Bari
- Benedetta Boari
- Benedetta Marigliano
- Benedetta Stancanelli
- Benfratelli Palermo
- Bologna
- Bologna
- Bologna
- Bologna)
- Brescia
- Bruno Graziella
- Bruno Tassone
- Busti Fabiana
- Cagliari
- Camilla Scarsi (Clinica Di Medicina Interna ad Indirizzo Oncologico
- Camillo Ferrandina
- Canetta Ciro
- Carl Margaria
- Carlo Custodero
- Carlo Sabbà
- Carmelinda Ruggiero
- Carmen Ricozzi (Policlinico Università della Campania L. Vanvitelli
- Cat- anzaro
- Catania
- Catania
- Catania
- Catanzaro
- Caterina Savriè (Azienda OspedalieraUniversitaria Sant'Anna
- Cesare Antonucci
- Cesare Poletto
- Chiara Dell’Unto (Università Campus Bio- Medico
- Chiara Lonati
- Chiara Mussi
- Chiara Sidoli
- Chiara Traversa
- Chiara Zurlo
- Chieti
- Christian Folli (Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico
- Christian Gracin
- Christiano Argano
- Città della Scienza e della Salute
- Claudia Catalano
- Claudio Borghi
- Clinica di Medicina Interna 2)
- Clinica e Terapia Medica)
- Clinica Medica 1
- Clinica Medica Generale e Terapia Medica)
- Clinica Medica I
- Clinica Medica I)
- Clinica Medica Università di Catania)
- Clinica Medica)
- Clinica Medica)
- Concetto Principato (Azienda Ospedaliera Universitaria Policlinico G. Martino
- Crisafulli Ernesto
- Cristina Fasolino (Azienda ospedaliera San Paolo
- Cuneo
- Damiani D’Ardes
- Daniela Calipari
- Daniela Lucente
- Daniela Tirotta
- Daniele Sola
- Davide Firinu
- Devis Benfaremo
- Di Cristina
- Diletta Maira
- Dipartimento di Medicina)
- Domenico Cerminara
- Domenico Girelli
- Domenico Investigators—Domenico Prisco
- Donatella Padula
- Edoardo Alessandro Pulixi (Azienda Ospedaliera della Pro- vincia di Lecco
- Edoardo Favale
- Elena Bigi
- Elena Silvestri
- Elena Spazzini
- Elena Succurro
- Eleonora Magnolfi
- Eleonora Semproni (Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico
- Elisa Pellegrini
- Elisabetta Cosi (Azienda Ospe- daliera Università di Padova
- Ema- nuele Amoruso
- Emanuela Miceli
- Emanuele Filippini
- Emanuele Valeriani
- Emato- logia non tumorale e Coagulopatie)
- Emilio Simeone
- Empoli
- Enrica 13 Internal and Emergency Medicine Internal and Emergency Medicine Bozzolo
- Enrica Negro
- Enrico Petrillo
- Enrico Strocchi
- Erica Larovere
- Erica Pagliaro
- Ermanno Angelucci (Ospedale Clinicizzato SS. Annunziata
- Eugenia Ianniello
- Eugenio Ruggeri
- Fabiana Busti
- Fabio Ferrando
- Fabio Tolloso (Ospedale Spirito Santo di Pescara
- Fabrizio Fabris
- Fabrizio Montecucco
- Federica Bellone
- Federica Cacioppo (Azienda Ospedaliera Universitaria Policlinico Giaccone Policlinico di Palermo
- Federica Cavallaro (A. R. N. A. S. Civico
- Federica Conti
- Federica Gandolfo (Ente Ospe- daliero Ospedali Galliera Genova
- Federica Giofrè (Università degli Studi Magna Grecia
- Federico Cattaneo (IRCCS Azienda Ospedaliera Universitaria San Martino-IST di Genova
- Federico Napoli
- Felice Cinque (Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico
- Ferrara
- Filippo Alessandro Montalto
- Firenze
- Flora Peyvandi
- Franc- esco Violi
- Francesca Loparco (Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
- Francesca Losa (Policlinico Universitario Duilio Casula
- Francesca Manzoni
- Francesca Mazzeo
- Francesca Mete
- Francesca Rotunno
- Francesco Baffa Bellucci
- Francesco Cipollone
- Francesco Corica
- Francesco Dentali (Università degli Studi dell'Insubria
- Francesco Purrello
- Francesco Purrello
- Francesco Ratti
- Francesco Salerno
- Francesco Saverio Vella
- Franco Arturi
- Franco Berti
- Gabriella D’Aurizio (Policlinico Universitario A. Gemelli
- Gabriella Gruden (Medicina Interna III
- Gen- ova
- Genova
- Genova
- Gerardo Mancuso
- Geriatria)
- Giacomo Argiolas
- Giacomo Bartelloni
- Giacomo De Luca
- Giacomo Emmi
- Giacomo Marchi (Azienda Ospedaliera Universitaria Integrata di Verona
- Giacomo Zaccherini (Azienda Ospe- daliera Policlinico Sant’Orsola-Malpighi
- Giada Pallini (IRCCS Policlinico San Donato e Università di Milano
- Giampaolo Damiani (Spedali Civili di Brescia
- Gian Paolo Fra
- Giancarlo Labbadia (Poli- clinico Umberto I
- Giandomen- ico Nigro Imperiale
- Gianluca Moroncini
- Gianni Biolo
- Ginevra Cambiè (IRCCS Policlinico San Matteo di Pavia
- Gio- vanna Fabio
- Gio- vanni Imbimbo (Policlinico Umberto I
- Giordano Sigon
- Giorgio Basile
- Giovanna Eusebi (Ospedale di Cattolica
- Giovanna Leoncini
- Giovanna Oberti
- Giovanni Lorenzo Squintani (ASST FatebenefratelliSacco
- Giovanni Michele De Vincenzo
- Giovanni Paoletti
- Giovanni Serafini
- Girelli
- Giulia Bogoni
- Giulia Bonini
- Giulia Cesaroni (Ospedale Poliambulanza
- Giulia Colombo
- Giulia Cono
- Giulia Costanzo
- Giulia Dondi
- Giulia Grignani
- Giulia Lancellotti
- Giulia Marta Viglione
- Giulia Nobili
- Giulia Principato
- Giulia Vannini (Ospedale San Giuseppe
- Giulia Vigani
- Giulia Vischi
- Giuliana Ceriani
- Giuseppe Bellelli
- Giuseppe Delitala
- Giuseppe Famularo
- Giuseppe Montalto
- Giuseppe Montrucchio
- Giuseppe Natoli
- Giuseppe Orio
- Giuseppe Paolisso
- Giuseppe Pio Martino
- Giuseppe Re
- Giuseppe Zuccalà
- Gloria Pina (Clinica San Carlo Casa di Cura Polispecialistica
- Graziana Lupattelli
- Hajnalka Szabo
- Ilaria Benzoni (Dipartimento di Scienze Mediche e Chirurgiche
- Ilaria Indiano
- Ilaria Lazzari
- Ilaria Rossi
- Ilenia Pareo (Azienda Ospedaliera Universitaria Poli- clinico S. Orsola-Malpighi
- Irene Bertozzi
- Irene Di Meo (Azienda Ospedaliera Universitaria della Seconda Università degli Studi di Napoli
- Irene Mattioli (Azienda Ospedaliero Universitaria Careggi Firenze
- Italia Aiello (Divisione di Medicina Interna
- Jacopo Alberto
- Lara Caserza
- Lara La Malfa
- Laura Orlandi
- Lavinia Pitotti
- Lecce
- Lecco
- Leonardo Campiotti
- Lidia Colangelo
- Ligia Dominguez
- Lina Falanga
- Lorenzo Biondi
- Lorenzo Cerruti
- Lorenzo Malatino
- Luana Castiglioni
- Luca Liberale (IRCCS Ospedale Policlinico San Martino e Università di Genova
- Luca Santi
- Luca Zanoli
- Lucia Carulli (Università di Modena e Reggio Emilia
- Lucia Esposito
- Lucia Sofia
- Lucia Trotta
- Luciano Colangelo
- Luciano Ottonello
- Lucio Monaco
- Ludovica Perri (Policlinico Umberto I
- Luigi Anastasio
- Luigi Fenoglio
- Luigi Fondrieschi
- Luigina Guasti
- Maddalena Fabrizi
- Mannucci Pier Mannuccio
- Marcello Giuseppe Maggio Gian Paolo Ceda
- Marco Bertolotti
- Marco Cattaneo
- Marco Filice Elvira Clausi (Università Geriatriche)
- Marco Novelli (Ospedale di Ciriè
- Marco Vincenzo Lenti
- Marco Zoli
- Margherita Grossi (Azienda Ospedaliero Uni- versitaria di Parma
- Margherita Migone De Amicis
- Maria Antonietta Bleve (Azienda Ospedaliera
- Maria Berria
- Maria Carbone (Ospedale Civile Jazzolino di Vibo Valentia
- Maria Domenica Cappellini
- Maria Elena Pipita (Policlinico Campus Biomedico Roma
- Maria Grazia Serra
- Maria Laura Mata- cena
- Maria Luisa Randi
- Maria Perticone
- Maria Rosaria Rizzo
- Maria Stella Pisciotta
- Maria Teresa Guag- nano
- Maria Valentina Amoruso
- Maria Victoria Rabuini
- Maria Vittoria Libbra
- Mario Barbagallo
- Mario Pirisi
- Mario Soldati
- Marta Clerici
- Marta Mancarella (Fon- dazione IRCCS Cà Granda Ospedale Maggiore Policlinico
- Martina Pisati
- Martina Ruvio
- Martino Brenna
- Massi- miliano Chiuch (Azienda Sanitaria Universitaria Integrata di Trieste
- Massimo Mattioli
- Massimo Porta
- Massimo R. Mannarino (Azienda Ospedaliera Santa Maria della Misericordia
- Massimo Raspanti
- Massimo Vanoli
- Matteo Galassi
- Matteo Pirro
- Mattia Bellan (Azienda Ospedaliera Universitaria Maggiore della Carità
- Mattia Brunori
- Maura Sanino (Dipartimento di Scienze Mediche
- Maurizio Corsi
- Maurizio Corsi (Università degli studi di Milano-Bicocca Ospedale S. Gerardo
- Maurizio Muscaritoli
- Mauro Ber- nardi
- Medicina Clinica)
- Medicina Clinica-Epatolo- gia)
- Medicina e Geriatria)
- Medicina Generale e delle Cure Avanzate)
- Medicina Generale e Malattie Aterotrombotiche e Degenerative)
- Medicina Generale e Sezione di Decisione Cli- nica)
- Medicina Generale per lo Studio ed il Trattamento dell’Ipertensione Arteriosa)
- Medicina Generale)
- Medicina III)
- Medicina III)
- Medicina Interna
- Medicina Interna
- Medicina Interna 1)
- Medicina Interna 1U).
- Medicina Interna 2
- Medicina Interna 2 Unità Indirizzo d'Urgenza)
- Medicina Interna Alta Intensità di Cure)
- Medicina Interna e Geriatria)
- Medicina Interna e Nutrizione Clinica Policlinico Umberto I)
- Medicina Interna e Specialità Mediche)
- Medicina Interna I)
- Medicina Interna I)
- Medicina Interna II)
- Medicina Interna Universitaria C. Frugoni)
- Medicina Interna)
- Medicina Interna)
- Medicina Interna)
- Medicina Interna)
- Medicina Interna)Guido Moreo
- Messina
- Michela Cammarosano
- Michela Pasino (Ospedale Civile Maggiore Borgo Trento
- Michela Zanetti
- Michele Zaccari
- Milano
- Milano
- Milano
- Milano
- Milano
- Milano
- Milano
- Milano Geriatria)
- Milano)
- Mirella Cilli
- Miriam Gino (AOU Città della Salute e della Scienza di Torino – Torino
- Miriam Gino (Ospedale degli Infermi di Rivoli
- Miriana Martelengo
- Monica Ormas
- Montichiari Brescia)
- Monza
- Moreno Tresoldi
- Mosè Bartone (Ospedale Giovanni Paolo II Lamezia Terme
- Multimedica IRCSS
- Napoli
- Nata- lia Scaramellini
- Nicola Lucio Liberato
- Nobili Alessandro
- Ortogeriatria e Riabilitazione)Franco Laghi Pasini
- Ospedale Civile di Baggiovara Unità Operativa di Geriatria)
- Ospedale di Casorate Primo
- Ospedale di Circolo e Fondazione Macchi
- Ospedale di Merate
- Ospedale S. Giovanni Battista Molinette
- Paderno Dugnano
- Padova
- Palermo
- Palermo
- Paola Fracasso
- Paola Nicolini (Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico
- Paolo Dionigi Rossi
- Paolo Gallo
- Paolo Mazzola
- Paolo Peasso
- Paolo Setti
- Pasquale Agosti
- Patrizia Mecocci
- Patrizia Sup- pressa
- Patrizia Tarsitani (Azienda Ospedaliera San Camillo Forlanini
- Pavia
- Pavia)
- Perugia
- Perugia
- Pier Leopoldo Capecchi (Azienda Ospedaliera Universitaria Senese
- Pietro Bocchi
- Pietro Castellino
- Pietro Minuz
- Pietro Pettinari
- Policlinico GB Rossi
- Policlinico Mater Domini
- Prima Clinica Medica)
- Raffaele Maio
- Raffaella Rossio
- Ranuccio Nuti
- Renzo Rozzini
- Reparto 11)
- Riccardo Alcidi
- Riccardo Ghio
- Riccardo Volpi
- Rimini
- Roberta Gonella
- Roberto Castello
- Roberto Davide Diprizio
- Roberto Leonardi
- Roberto Man- fredini
- Roberto Pontremoli
- Roberto Quadri
- Roberto Romiti (Clinica Medica
- Roberto Tar- quini
- Roberto Val- enti
- Roma
- Roma
- Roma
- Roma
- Roma
- Roma Roma
- Rosa Battaglia
- Rosa Scurti
- Rosario Di Quattro
- Rossella Caruso (Azienda Ospedaliera per l'Emergenza Cannizzaro
- Ruana Tiseo
- S. C. Medicina Interna)
- S. C. Medicina Interna)
- Salam Kassem
- Salvatore Corrao
- Salvatore Di Marca
- Salvatore D’Aniano (Azienda Sanitaria Ospedaliera Santa Croce e Carle di Cuneo
- Salvatore Fragapani
- Salvatore Minisola
- Salvatore Mularo
- Salvatore Piro (Ospedale Garibaldi Nesima
- Samuele Pignataro (Azienda Ospedaliera Universitaria Poli- clinico – V. Emanuele
- San Donato Milanese
- Sapienza Università di Roma
- Sara del Vec- chio
- Sara Scarduelli
- Sarah Damanti (IRCCS Ospedale San Raffaele – Milano
- Sarah Morellini (Azienda Ospedaliera Universi- taria Verona
- Sartori Giulia
- SC Geriatria Dipartimento Cure Geriatriche
- Semeiotica Medica Bernardi)
- Sergio Harari
- Siena
- Siena
- Silvia Cappelli
- Silvia Dolenti
- Silvia Li Bassi
- Silvia Prolo
- Silvia Prolo
- Silvia Schiavone
- Silvia Tiraboschi
- Simona Leoni
- Simona Leoni
- Simona Sestili
- Simonetta Mor- ganti
- SMSC03Medicina Interna F e Malattie Meta- boliche dell'osso)
- SOD Medicina Interna Interdisciplinare)
- Sonia Seghezzi
- Spedali Civili
- Stefano Baldassarre
- Stefano Buf- felli
- Stefano Del Giacco
- Struttura Complessa di Geriatria)
- Tancredi Prandini
- Tania Falbo
- Teresa De Falco
- Teresa Salvatore
- Tiziana Meschi
- Tiziana Tognin (ASST di Pavia
- Tiziano Lucchi
- Torino
- Torino
- Torino
- Torino)
- U. O Medicina Interna e Lungodegenza Critica)
- U. O. 3a Medicina Generale)
- U. O. C Clinica Geriatrica)
- U. O. C Medicina Interna)
- Umberto Vespasiani Gentilucci
- Unità Operativa Clinica Medica)
- Unità Operativa Complessa di Medicina Interna)
- Unità Operativa Complessa di Medicina Interna)
- Unità Operativa Complessa Medicina 2)
- Unità Operativa Complessa Medicina d'Urgenza e Pronto Soccorso)Giuseppe Romanelli
- Unità Operativa Complessa Medicina Interna)
- Unità Operativa Complessa Medicina)
- Unità Operativa di Geri- atria)
- Unità Operativa di Geri- atria)
- Unità Operativa di Geriatria e Lun- godegenza)
- Unità Operativa di Medicina Generale Emilio Bernardelli)
- Unità Operativa di Medicina Interna
- Unità Operativa di Medicina Interna Borghi)
- Unità Operativa di Medicina Interna Zoli)
- Unità Operativa Medicina Interna IA)
- Università degli Studi di Bologna/ Azienda Ospedaliero- Universitaria S. Orsola-Malpighi
- Università di Torino
- UOC di Medicina Interna)
- UOC Medicina Generale ad Indirizzo Metabolico)
- UOC Medicina Interna ad Indirizzo Geriatrico- Riabilitativo)
- UOC Medicina Interna)
- UOSD Medicina Interna
- USL Toscana Centro
- Valentina Antoci
- Valentina Beccati
- Valentina Terranova
- Valentino Condoleo
- Valeria De Sando
- Valeria Di Stefano
- Valeria Savojardo
- Valter Monzani
- Vanessa Bianconi
- Varese
- Verona
- Verona
- Verona
- VI Divisione di Medicina Interna e Malattie Nutrizionali dell'Invecchiamento)
- Vianello Alice
- Vibo Val- entia
- Vincenza Beneduce
- Vincenzo Stanghellini
- Virginia Boccardi (Università degli Studi di Perugia-Azienda Ospedaliera S. M. della Misericordia
- Vittorio Durante
- William Capeci
- Yasmine Grassi
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2023
- Field of study
Background and objective: Chronic obstructive pulmonary disease (COPD) and heart failure (HF) mutually increase the risk of being present in the same patient, especially if older. Whether or not this coexistence may be associated with a worse prognosis is debated. Therefore, employing data derived from the REPOSI register, we evaluated the clinical features and outcomes in a population of elderly patients admitted to internal medicine wards and having COPD, HF or COPD + HF. Methods: We measured socio-demographic and anthropometric characteristics, severity and prevalence of comorbidities, clinical and laboratory features during hospitalization, mood disorders, functional independence, drug prescriptions and discharge destination. The primary study outcome was the risk of death. Results: We considered 2,343 elderly hospitalized patients (median age 81 years), of whom 1,154 (49%) had COPD, 813 (35%) HF, and 376 (16%) COPD + HF. Patients with COPD + HF had different characteristics than those with COPD or HF, such as a higher prevalence of previous hospitalizations, comorbidities (especially chronic kidney disease), higher respiratory rate at admission and number of prescribed drugs. Patients with COPD + HF (hazard ratio HR 1.74, 95% confidence intervals CI 1.16-2.61) and patients with dementia (HR 1.75, 95% CI 1.06-2.90) had a higher risk of death at one year. The Kaplan-Meier curves showed a higher mortality risk in the group of patients with COPD + HF for all causes (p = 0.010), respiratory causes (p = 0.006), cardiovascular causes (p = 0.046) and respiratory plus cardiovascular causes (p = 0.009). Conclusion: In this real-life cohort of hospitalized elderly patients, the coexistence of COPD and HF significantly worsened prognosis at one year. This finding may help to better define the care needs of this population
Supervised Component Generalized Linear Regression using a PLS-extension of the Fisher scoring algorithm
- Author
- ALESSANDRA NORA
- ANDREA ANGELINI
- ANTOVA
- AZIENDA OSPEDALIERA CAREGGI
- AZIENDA OSPEDALIERA CARLO POMA
- AZIENDA OSPEDALIERA S. GIOVANNI ADDOLORATA
- AZIENDA OSPEDALIERA SPEDALI CIVILI
- BOLOGNA
- BRESCIA
- CARLO PRATESI
- CARLO SETACCI
- CHIETI
- COORDINATING CENTER
- CORE LAB ANALYSIS
- CRISTIAN MANETTA
- DE TROIA Alessandro
- EDOARDO CERVI
- FABIO VERZINI
- FIRENZE ROBERTOPACCHIONI
- FRANCESCO SETACCI
- FRANCESCO SPIGONARDO
- GIANBATTISTA PARLANI
- GIOVANNI PRATESI
- GIUSEPPE BIANCHI
- GIUSEPPE PANUCCIO
- GUSTAVO IACONO
- GUSTAVO IACONO
- JOURNAL OF VASCULAR SURGERY
- LAURA UKOVICH
- LUCIANO CARBONARI
- LUCIANO PEDRINI
- LUIGI SENSI
- LYDIA ROMANO
- MARCO GARDANI
- MAURIZIO TEDOLI
- NUMBER CAO
- OSPEDALE C.L.I.N.I.C.I.Z.Z.A.T.O.S. S. ANNUZIATA
- OSPEDALE DI ANCONA
- OSPEDALE MAGGIORE
- OSPEDALI RIUNITI DI TRIESTE
- PAOLA DE RANGO
- PARMA
- PARTICIPATING CENTERS
- PERUGIA PIERGIORGIO CAO
- PIERFRANCO SALCUNI
- POLICLINICO LE SCOTTE
- ROBERTO ADOVASIO
- ROCCO GIUDICE
- ROMA
- SALCUNI Pierfranco
- SIENA
- STEFANO BONARDELLI
- TRIESTE
- UNIVERSITÀ DEGLI STUDI DI PARMA
- UNIVERSITÀ DI SIENA
- VOLUME
- Publication venue
- Elsevier
- Publication date
- 01/01/1989
- Field of study
International audienc
QUALITY OF LIFE AND TREATMENT SATISFACTION IN PATIENTS WITH TYPE 1 DIABETES: A COMPARISON BETWEEN CONTINUOUS SUBCUTANEOUS INSULIN INJECTION AND MULTIPLE DAILY INJECTIONS
- Author
- - Seconda Università di Napoli
- A Bertolotto
- A Ciucci - Ospedale di Mariano Comense (CO)
- A Clementi
- A Corsi
- A Di Flaviani / ML Manca Bitti
- A Iannilli - Università Politecnica di Ancona
- A Laurenzi - Istituto Scientifico Ospedale San Raffaele
- A Moretti
- A Pianta - CAD Bassano - Bassano del Grappa (VI)
- A Veronelli
- AA Turco - AOU Università Federico II
- AC Babini - Ospedale degli Infermi
- Acquaviva delle Fonti (BA)
- AM Cernigoi - Ospedale San Paolo
- Amoretti R
- Ancona
- AO G. Salesi
- Arenzano (GE)
- ASL RMB
- Aurisina (TS)
- B Agosti - Spedali Civili di Brescia
- B Shashaj - Università La Sapienza
- Bruttomesso D
- Busetto R
- C Bordone - AO Università San Martino
- C Landi - ASUR Marche
- C Mauri - Ospedale San Paolo
- C Noacco - AO Universitaria
- C Suraci
- C Tortul
- C Tubili – AO San Camillo Forlanini
- Camogli (GE)
- Capani F
- Catania
- Chieti e Pescara
- Cremona
- D Crazzolara
- D Fava
- Di Bartolo P
- E Manca - ASS 1 Triestina
- E Meneghini - AO Ospedale Niguarda Ca' Granda
- E Torlone
- E Zarra
- F Meschi / G Galimberti
- F Sciarretta - PO San Salvatore
- F Capani - Università G D’Annunzio
- F Giorgino
- F Massimiani - AO S. Giovanni Addolorata
- F Pellicano - AUSL Provincia di Ravenna
- F Prisco
- Fermo
- Firenze
- Forlì
- Franciosi M
- G Annuzzi
- G Beltramello
- G Careddu - Ospedale SS Prosperie Caterina
- G d'Annunzio
- G Forlani
- G Grassi
- G Lepore - Ospedali Riuniti di Bergamo
- G Marchesini - Università degli Studi di Bologna
- G Mariani
- G Ridola - Poliambulatorio Oreto Guadagna
- G Testori
- Genova
- Genova
- Girelli A
- I Franzetti
- I Tanganelli - Università degli Studi di Siena
- Iafusco D
- L Bozzetto / A Franzese
- L Cataldi
- L Corgiat Mansin - Ospedale Oftalmico ASL 1
- L Sciangula
- L Strazzera - Ospedale Civico di Partitico
- L Tomaselli
- L Tonutti
- L'Aquila
- Larino (CB)
- Leonetti F
- M Agrusta
- M Aragona - AO Universitaria Pisana
- M Bonomo
- M Dal Pos - Università degli Studi di Padova
- M Maiello - F Leonetti
- M Marchesi - Ospedale di Bolzano
- M Michelini - Ospedale di Montecchio
- M Nizzoli
- M Orsini Federici - Università degli Studi di Perugia
- M Parenti
- M Piscopo - AORN A Cardarelli
- M Rossana - Ospedale A Murri
- M Tagliaferri
- M Tomelini - ASO San Giovanni Battista di Torino
- M Trovati
- M Velussi - Casa di Cura Pineta del Carso
- MA Lezzi - Ospedale G Vietri
- Maione A
- ME De Feo
- MF Reali - AO Universitaria degli Studi Meyer
- Milano
- Milano
- Milano
- Milano
- Milano
- Monfalcone (GO)
- Morviducci L
- MT Anzellotti / E Vitacolonna
- N Minuto - Istituto G Gaslini
- N Tota - Ospedale Generale Regionale Miulli
- Napoli
- Napoli
- Nicolucci A
- Orbassano (TO)
- P Ponzani - UOC Genova Ponente
- P Borboni
- P Buono / S Turco
- P Colapinto - AO San Carlo Borromeo
- P Di Bartolo
- P Di Berardino - PO di Atri (TE)
- P Foglini
- P Marnini - AO Universitaria
- P Massucco - AS Ospedale San Luigi Gonzaga
- P Pozzilli
- P Rampini - AO Fatebenefratelli e Oftalmico
- P Ruggeri - Azienda Istituti Ospedalieri
- Palermo
- Palermo
- Pisa
- Policlinico Umberto I
- Ponzi P
- R Bonfanti
- R Candido
- R De Luca
- R Iannarelli
- R Trevisan
- R Vigneri - Ospedale Garibaldi Nesima
- Reggio Emilia
- Rimini
- Roma
- Roma
- Roma
- Roma
- Roma
- Roma
- S Aquati - Ospedale Morgagni
- S Carletti - Ospedale Sandro Pertini
- S Costa
- S Manfrini
- S Manfrini - Università Campus Bio-Medico
- S Piccinini - AO Universitaria Policlinico Tor Vergata
- S Toni
- S Tumini
- Senigallia (AN)
- SO La Colletta
- Torino
- Trieste
- Udine
- V Gigantelli - Università degli Studi di Bari
- V Cherubini
- V Di Blasi - PO di Cava dei Tirreni (SA)
- V Manicardi
- V Montani
- V Provenzano
- Varese.
- VC Iannucci - N Sulli
- VitacolonnaE on behalf of the EQuality Study Group:LV Cassano
- Zona Territoriale n. 4
- Publication venue
- Publication date
- Field of study
Additional file 33 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
- Author
- Aadahl Mette
- Abbas Shahid
- Abecasis Goncalo
- Aberdeen Centre for Health Data Science
- Academia Sinica Institute of Biomedical Sciences
- Academy of Scientific and Innovative Research (AcSIR)
- Adair Linda S.
- Adams Hieab H. H.
- Adeyemo Adebowale A.
- Aguilar-Salinas Carlos A.
- Akiyama Masato
- Al-Mulla Fahd
- Alexandria University
- Algebra University College
- Arbeeva Liubov
- Arctic Centre Univ. of Groningen
- Arnett Donna K.
- Asselbergs Folkert W.
- Assimes Themistocles L.
- Atlanta VA Health Care System
- Attia John
- Banas Bernhard
- Bandinelli Stefania
- Baras Aris
- Barts and The London School of Medicine and Dentistry
- Bayyana Swati
- Bechayda Sonny Augustin
- Beijing Institute for Brain Disorders
- Benjamins Jan W.
- Bennett David A.
- Bentley Amy R.
- Berlin Institute of Health
- Beulens Joline W. J.
- Bharadwaj Dwaipayan
- Bhatti Konain Fatima
- BHF Glasgow Cardiovascular Research Centre Faculty of Medicine
- Bielak Lawrence F.
- Biino Ginevra
- Bis Joshua C.
- Bispebjerg and Frederiksberg Hospital
- Bjerregaard Anne A.
- Black Corri
- Boehnke Michael
- Bollepalli Sailalitha
- Boomsma Dorret I.
- Bork-Jensen Jette
- Bornholms Hospital
- Boston University School of Public Health
- Bouchard Claude
- Bradfield Jonathan P.
- Bradford Yuki
- Brandslund Ivan
- Braund Peter S.
- Broad Institute
- Brody Jennifer A.
- Brown Christopher D.
- Brown Michael R.
- Brown Morris
- Brumpton Ben M.
- Buring Julie E.
- Burtt Noël P.
- Böger Carsten A.
- Cade Brian E.
- Cai Qiuyin
- Campbell Archie
- Campbell Harry
- Capital Medical University
- Case Western Reserve University
- Caulfield Mark J.
- Cañadas-Garre Marisa
- Center for Non-Communicable Diseases
- Centre for Genomics and Oncological Research: Pfizer-University of Granada-Andalusian Regional Government
- Chai Jin Fang
- Chambers John C.
- Chandak Giriraj R.
- Chang Kyong-Mi
- Chasman Daniel I.
- Chaturvedi Nish
- Chen Shufeng
- Chen YEugene
- Chen Yii-Der Ida
- Chen Zhengming
- Cheng Ching-Yu
- Children's Hospital Oakland Research Institute
- Children's Hospital Philadelphia and University of Pennsylvania School of Medicine
- Chinese Academy of Medical Sciences &
- Chinese National Human Genome Center at Shanghai
- Chitrala Kumaraswamy Naidu
- Cho Kelly
- Cho Yoon Shin
- Choi Hyeok Sun
- Choudhury Ananyo
- Christensen Henry
- Christensen Kaare
- Christian-Albrechts-Universitaet zu Kiel
- Christofidou Paraskevi
- Chuang Lee-Ming
- Churchill Hospital
- CIBER en Bioingeniería Biomateriales y Nanomedicina (CIBER-BBN)
- CIBIOR
- Cincinnati Children's Hospital Medical Center
- Ciullo Marina
- Clarendon Laboratory
- Clarke Shoa L.
- Clinical Trial Service Unit and Epidemiological Studies Unit
- College of Life Sciences
- College of Medicine
- Columbia University Mailman School of Public Health
- Concas Maria Pina
- Consejo Nacional de Ciencia y Tecnología
- Correa Adolfo
- Costanzo Maria C.
- Couture Christian
- Cruz Miguel
- CSIR-Centre for Cellular and Molecular Biology
- CSIR-Institute of Genomics and Integrative Biology
- Cuellar-Partida Gabriel
- Cupples LAdrienne
- Damrauer Scott M.
- Dantoft Thomas M.
- Dasman Diabetes Institute
- Data Tecnica International
- Data Tecnica International
- David Geffen School of Medicine at UCLA
- Daviglus Martha
- Daw EWarwick
- de Borst Gert J.
- de Graaf Jacqueline
- De Jager Philip L.
- de Kleijn Dominique
- de Silva H. Janaka
- de Vries Paul S.
- deCODE genetics/Amgen Inc.
- Dedoussis George
- Delgado Graciela E.
- Deloukas Panos
- Demirkan Ayşe
- Department of Clinical Neuroscience
- Department of Epidemiology
- Department of Epidemiology and Data Science Amsterdam UMC
- Department of General Practice Amsterdam UMC
- Department of Nephrology Instituto de Investigaciones Biomédicas Sant Pau
- Deutsches Herzzentrum München
- Dipartimento di Chimica e Farmacia Università di Sassari
- Dorajoo Rajkumar
- Doumatey Ayo P.
- Dromokaiteio Psychiatric Hospital
- Duke-NUS Medical School Singapore
- DZHK (German Centre for Cardiovascular Research) Partner site Greifswald
- Ealing Hospital
- Elders Petra J. M.
- Emory University
- Emory University School of Medicine
- Engmann Jorgen
- Erasmus University Medical Center
- Erdmann Jeanette
- EURAC Research Affiliated Institute of the University of Lübeck
- Evans Michele K.
- Ewha Womans University
- Ewha Womans University School of Medicine
- Faisalabad Institute of Cardiology
- Farmaki Aliki-Eleni
- Faul Jessica D.
- Feitosa Mary F.
- Feng QiPing
- Fernandez-Lopez Juan Carlos
- Fimlab Laboratories Department of Clinical Chemistry
- Finnish Institute for Health and Welfare
- Forer Lukas
- Fornage Myriam
- Francesco Cucca
- Frank Mirjam
- Franke Andre
- Franks Paul W.
- Frayling Timothy M.
- Fred Hutchinson Cancer Research Center
- Freie Universität Berlin
- Freitag-Wolf Sandra
- Fuchsberger Christian
- Fuwai Hospital Chinese Academy of Medical Sciences &
- Galesloot Tessel E.
- Gao Zishan
- Gaziano John M.
- Geisinger
- Genome Institute of Singapore
- George Institute for Global Health at Peking University Health Science Centre
- George Washington University
- German Center for Diabetes Research
- German Centre for Integrative Biodiversity Research (iDiv) Halle-Jena-Leipzig
- German Chronic Kidney Disease Study
- German Institute of Human Nutrition
- Ghanbari Mohsen
- Giannakopoulou Olga
- Giardoglou Tota
- Gieger Christian
- Girotto Giorgia
- Giulianini Franco
- Glenfield Hospital
- Goel Anuj
- Golightly Yvonne M.
- Gordon-Larsen Penny
- Graduate School of Medical Sciences
- Graduate School of Medicine
- Graff Mariaelisa
- Graham Sarah E.
- Grant Struan F. A.
- Grarup Niels
- Gu Dongfeng
- Gudbjartsson Daniel F.
- Gudnason Vilmundur
- Guo Xiuqing
- Gustafsson Stefan
- Haessler Jeffrey
- Hakonarson Hakon
- Hallym University
- Han Sohee
- Hansen Torben
- Harbor-UCLA Medical Center
- Harokopio University
- Hart Leen M.‘t
- Harvard Medical School
- Harvard School of Public Health
- Hattersley Andrew T.
- Havulinna Aki S.
- Haworth Simon
- Hayes M. Geoffrey
- Hayward Caroline
- Hazelhurst Scott
- Hebbar Prashantha
- Heid Iris M.
- Helgadottir Anna
- Helsinki University Central Hospital
- Heng Chew-Kiat
- Hewitt Alex W.
- Hidalgo Bertha
- High Tech Campus 4
- Hilliard Austin T.
- Hindy George
- Hirschhorn Joel N.
- Hishigaki Haretsugu
- Ho Yuk-Lam
- Hoefer Imo E.
- Hofer Edith
- Hollander Anneke Iden
- Holm Hilma
- Holmes Michael V.
- Homuth Georg
- Hospital of Southern Jutland
- Hottenga Jouke Jan
- Huang Hongyan
- Huang Jianfeng
- Huang Wei
- Huck Institutes of the Life Sciences
- Huerta-Chagoya Alicia
- Hui Qin
- Hung Yi-Jen
- Hunt Karen A.
- Hunt Steven C.
- Huo Shaofeng
- Hutri-Kähönen Nina
- Hveem Kristian
- Hwang Mi Yeong
- Hwu Chii-Min
- Icahn School of Medicine at Mount Sinai
- Icelandic Heart Association
- Ichihara Sahoko
- Iha Hiroyuki
- Ikeda Daisuke D.
- Ikram M. Arfan
- Imperial College
- Imperial College and Imperial Healthcare NHS Trust
- Imperial College London
- Ingelsson Erik
- Institute for Maternal and Child Health - IRCCS Burlo Garofolo
- Institute of Epidemiology 2
- Institute of Genetics and Biophysics “Adriano Buzzati-Traverso” - CNR
- Institute of Molecular and Clinical Ophthalmology
- Institute of Nutrition and Functional Foods (INAF)
- Instituto de Investigación Biosanitaria de Granada (ibs.GRANADA)
- Instituto Nacional de Medicina Genómica
- InstitutoNacional de Salud Publica Y Centro de Estudios en Diabetes
- Interuniversity Cardiology Institute of The Netherlands
- IRCCS Neuromed
- Irvin Marguerite R.
- Istituto di Ricerca Genetica e Biomedica
- Jackson Rebecca D.
- Jang Dongkeun
- Jang Hye-Mi
- Jarvelin Marjo-Riitta
- Jarvik Gail P.
- Jawaharlal Nehru University
- Ji Yingji
- Jichi Medical University
- Jin Zi-Bing
- John Radcliffe Hospital
- Jonas Jost B.
- Joshi Peter K.
- Jousilahti Pekka
- JSS Academy of Higher Education and Research
- Jukema J. Wouter
- Jung Bettina
- Justice Anne E.
- Jäger Susanne
- Jöckel Karl-Heinz
- Kamatani Yoichiro
- Kanai Masahiro
- Kanoni Stavroula
- Kaprio Jaakko
- Kardia Sharon L. R.
- Karpe Fredrik
- Kathiresan Sekar
- Kato Norihiro
- Katsuya Tomohiro
- Kawaguchi Takahisa
- Kee Frank
- Kentistou Katherine A.
- KfH Kidney Center Traunstein
- Khera Amit V.
- Khor Chiea Chuen
- Kiemeney Lambertus A. L. M.
- Kim Bong-Jo
- Kim Eung Kweon
- Kim Han-Na
- Kim Hyung-Lae
- Kim Young Jin
- King Abdulaziz University
- King's College London
- Kivimaki Mika
- Klarin Derek
- Kleber Marcus E.
- Klinikum rechts der Isar der TU Muenchen
- Koh Woon-Puay
- Koistinen Heikki A.
- Kolcic Ivana
- Kooner Jaspal S.
- Kooperberg Charles
- Kovacs Peter
- Kraaijeveld Adriaan O.
- Kraft Peter
- Krauss Ronald M.
- Kronenberg Florian
- Kubo Michiaki
- Kullo Iftikhar J.
- Kumari Meena
- Kurbasic Azra
- Kurume University School of Medicine
- Kutalik Zoltan
- Kuusisto Johanna
- Kyoto University Graduate School of Medicine
- Kyung Hee University School of Medicine
- Kähönen Mika
- Kårhus Line L.
- Laakso Markku
- Laboratory for Financial Engineering of Laval University
- Lamina Claudia
- Landspitali University Hospital
- Lange Leslie A.
- Langenberg Claudia
- Launer Lenore J.
- Le Phuong
- Lee Kong Chian School of Medicine
- Lee Hyejin
- Lee Jong Young
- Lehtimäki Terho
- Leiden University Medical Center
- Leipzig University Hospital
- Leonard Hampton L.
- Lettre Guillaume
- Li Hengtong
- Li Huaixing
- Li Liming
- Li Xiaohui
- Li Xiaoyin
- Liang Jingjing
- Lieb Wolfgang
- Life Course Epidemiology (LCE)
- Lin Kuang
- Lin Maoxuan
- Lin Shih-Yi
- Lin Xu
- Lind Lars
- Lingren Todd
- Linneberg Allan
- Liu Fangchao
- Liu Jianjun
- Liu Jun
- Lo Ken Sin
- Local Health Unit Toscana Centro
- Locke Adam E.
- Loeffler Markus
- London North West University Healthcare NHS Trust
- Long Jirong
- Loos Ruth J. F.
- Lorés-Motta Laura
- Loukola Anu
- Ltd
- Lu Xiangfeng
- Luan Jian’an
- Lund University
- Lund University Diabetes Centre
- Lynch Julie A.
- Lyssenko Valeriya
- Lyytikäinen Leo-Pekka
- Magnusson Patrik K. E.
- Mahajan Anubha
- MAHSC University of Manchester
- Mamakou Vasiliki
- Mangino Massimo
- Manichaikul Ani
- Marouli Eirini
- Marques-Vidal Pedro
- Marten Jonathan
- Martin Hilary C.
- Martin Lisa Warsinger
- Martin Nicholas G.
- Mashhad University of Medical Sciences School of Medicine
- MASPEC Institut
- Massachusetts General Hospital
- Massachusetts General Hospital Cancer Center
- Massachusetts Institute of Technology
- Matsuda Fumihiko
- Matteo Floris
- Mauro Pala
- Mayo Clinic
- McCarthy Mark I.
- McDaid Aaron F.
- McKnight Amy Jayne
- Medical University of Graz
- Medina-Gomez Carolina
- Medizinische Universitat Innsbruck
- Meidtner Karina
- Mellström Dan
- Mercader Josep M.
- Milken Institute School of Public Health
- Miller Jason E.
- Millwood Iona Y.
- Minerva Foundation Institute for Medical Research Helsinki
- Mitchell Jonathan S.
- Mitchell Paul
- Mitchell Ruth E.
- Mohlke Karen L.
- Mook-Kanamori Dennis O.
- Mori Trevor A.
- Morris Andrew P.
- Morrison Alanna C.
- MRC Epidemiology Unit
- MRC Human Genetics Unit
- MRC Integrative Epidemiology Unit at the University of Bristol
- MRC Unit for Lifelong Health and Ageing
- Munroe Patricia B.
- Munz Matthias
- Murakami Yoshinori
- Männikkö Minna
- März Winfried
- Møllehave Line T.
- Nabika Toru
- Nagoya University Graduate School of Medicine
- Nakatochi Masahiro
- Nalls Mike A.
- Namjou Bahram
- Nanjing University of Chinese Medicine
- Nardone Giuseppe Giovanni
- Narita Akira
- Natarajan Pradeep
- National and Kapodistrian University of Athens
- National Center for Global Health and Medicine
- National Defense Medical Center Taiwan
- National Heart Lung, and Blood Institute (NHLBI)
- National Human Genome Research Institute
- National Institute of Health
- National Institute of Medical Sciences and Nutrition Salvador Zubirán
- National Institute on Aging
- National Institutes of Health Bethesda
- National Taiwan University Hospital
- National University Heart Centre
- National University Heart Centre Singapore
- National Yang Ming University
- Nelson Amanda E.
- Nelson Christopher P.
- Nethander Maria
- Neville Matt J.
- Newcastle University
- Nielsen Aneta A.
- NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust
- Niinikoski Harri
- Nikus Kjell
- Nongmaithem Suraj S.
- Noordam Raymond
- North Kari E.
- Northwestern University
- Northwestern University Feinberg School of Medicine
- Norwegian University of Science and Technology
- Novo Nordisk Foundation Center for Basic Metabolic Research
- Ntalla Ioanna
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- Wojczynski Mary K.
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- Åsvold Bjørn Olav
- Publication venue
- figshare
- Publication date
- 01/01/2023
- Field of study
Additional file 33: Table S22. Mouse genes with lipid phenotypes (silver set)
Additional file 17 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
- Author
- Aadahl Mette
- Abbas Shahid
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- Atlanta VA Health Care System
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- Vrije Universiteit Amsterdam de Boelelaan
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- Wang Chaolong
- Wang Jun-Sing
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- Wang Zhe
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- Warner Sophie C.
- Warren Helen R.
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- Washington University School of Medicine in St. Louis
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- Weir David R.
- Weiss Stefan
- Wellcome Sanger Institute
- Wellcome Trust Centre for Human Genetics
- Wenzhou Medical University
- Westlake Laboratory of Life Sciences and Biomedicine
- Westlake University
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- Wickremasinghe Ananda R.
- Widén Elisabeth
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- Wild Sarah H.
- Willemsen Allegonda H. M.
- Willer Cristen J.
- Wilson James F.
- Wilson James G.
- Wilson Peter W. F.
- Winkler Thomas W.
- Wojczynski Mary K.
- Wong Andrew
- Wong Tien-Yin
- Woo Jeong-Taek
- Wood Andrew R.
- Wu Jer-Yuarn
- Wu Kuan-Han H.
- Xia Rui
- Xue Chao
- Yamamoto Masayuki
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- Yin Xianyong
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- Yousri Noha A.
- Yu Ketian
- Yuan Jian-Min
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- Zeng Lingyao
- Zhang Jifeng
- Zhang Weihua
- Zhao Jing-Hua
- Zhao Wei
- Zheng Wei
- Zhou Wei
- Zhu Xiang
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- Åsvold Bjørn Olav
- Publication venue
- figshare
- Publication date
- 01/01/2023
- Field of study
Additional file 17: Table S9. PheWAS UKB-MVP meta-analysis results for each index lipid variant at Bonferroni threshold for multiple testing
Additional file 27 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
- Author
- Aadahl Mette
- Abbas Shahid
- Abecasis Goncalo
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- Atlanta VA Health Care System
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- Institute for Biomedicine (affiliated with the University of Lübeck)
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- van Heel David A.
- van Meurs Joyce B. J.
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- Veturi Yogasudha
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- Vrije Universiteit Amsterdam de Boelelaan
- VU University Medical Center
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- Walker Mark
- Walters Robin G.
- Wang Carol A.
- Wang Chaolong
- Wang Jun-Sing
- Wang Ya Xing
- Wang Yuxuan
- Wang Zeyuan
- Wang Zhe
- Wareham Nicholas J.
- Warner Sophie C.
- Warren Helen R.
- Washington University in St. Louis
- Washington University School of Medicine in St. Louis
- Watkins Hugh
- Wei Wei-Qi
- Wei Wen B.
- Weill Cornell Medicine-Qatar
- Weir David R.
- Weiss Stefan
- Wellcome Sanger Institute
- Wellcome Trust Centre for Human Genetics
- Wenzhou Medical University
- Westlake Laboratory of Life Sciences and Biomedicine
- Westlake University
- Whitfield John B.
- Wickremasinghe Ananda R.
- Widén Elisabeth
- Wielscher Matthias
- Wild Sarah H.
- Willemsen Allegonda H. M.
- Willer Cristen J.
- Wilson James F.
- Wilson James G.
- Wilson Peter W. F.
- Winkler Thomas W.
- Wojczynski Mary K.
- Wong Andrew
- Wong Tien-Yin
- Woo Jeong-Taek
- Wood Andrew R.
- Wu Jer-Yuarn
- Wu Kuan-Han H.
- Xia Rui
- Xue Chao
- Yamamoto Masayuki
- Yang Bin
- Yang Jian
- Yang Jingyun
- Yao Jie
- Yin Xianyong
- Yokota Mitsuhiro
- Yong Loo Lin School of Medicine
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- Yoon Kyungheon
- Yousri Noha A.
- Yu Ketian
- Yuan Jian-Min
- Zajac Greg J. M.
- Zeggini Eleftheria
- Zeng Lingyao
- Zhang Jifeng
- Zhang Weihua
- Zhao Jing-Hua
- Zhao Wei
- Zheng Wei
- Zhou Wei
- Zhu Xiang
- Zhu Xiaofeng
- Zilhao Nuno R.
- Zimmermann Martina E.
- Zmuda Joseph M.
- Zonderman Alan B.
- Åsvold Bjørn Olav
- Publication venue
- figshare
- Publication date
- 01/01/2023
- Field of study
Additional file 27: Table S17. Sex-stratified effect sizes in UK Biobank considering all individuals or only those not on cholesterol lowering medications
Additional file 28 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
- Author
- Aadahl Mette
- Abbas Shahid
- Abecasis Goncalo
- Academia Sinica Institute of Biomedical Sciences
- Academy of Scientific and Innovative Research (AcSIR)
- Adair Linda S.
- Adams Hieab H. H.
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- Alexandria University
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- Arnett Donna K.
- Asselbergs Folkert W.
- Assimes Themistocles L.
- Atlanta VA Health Care System
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- Attikon University Hospital
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- Beijing Institute for Brain Disorders
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- Benjamins Jan W.
- Bennett David A.
- Bentley Amy R.
- Beulens Joline W. J.
- Bharadwaj Dwaipayan
- Bhatti Konain Fatima
- BHF Glasgow Cardiovascular Research Centre Faculty of Medicine
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- Biino Ginevra
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- Bispebjerg and Frederiksberg Hospital
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- Blood Institute's and Boston University's Framingham Heart Study
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- Verweij Niek
- Vestergaard Henrik
- Veturi Yogasudha
- Villalpando Clicerio Gonzalez
- Virgen de las Nieves University Hospital
- Vitart Veronique
- Vrije Universiteit Amsterdam de Boelelaan
- VU University Medical Center
- Völzke Henry
- Walker Mark
- Walters Robin G.
- Wang Carol A.
- Wang Chaolong
- Wang Jun-Sing
- Wang Ya Xing
- Wang Yuxuan
- Wang Zeyuan
- Wang Zhe
- Wareham Nicholas J.
- Warner Sophie C.
- Warren Helen R.
- Washington University in St. Louis
- Washington University School of Medicine in St. Louis
- Watkins Hugh
- Wei Wei-Qi
- Wei Wen B.
- Weill Cornell Medicine-Qatar
- Weir David R.
- Weiss Stefan
- Wellcome Sanger Institute
- Wellcome Trust Centre for Human Genetics
- Wenzhou Medical University
- Westlake Laboratory of Life Sciences and Biomedicine
- Westlake University
- Whitfield John B.
- Wickremasinghe Ananda R.
- Widén Elisabeth
- Wielscher Matthias
- Wild Sarah H.
- Willemsen Allegonda H. M.
- Willer Cristen J.
- Wilson James F.
- Wilson James G.
- Wilson Peter W. F.
- Winkler Thomas W.
- Wojczynski Mary K.
- Wong Andrew
- Wong Tien-Yin
- Woo Jeong-Taek
- Wood Andrew R.
- Wu Jer-Yuarn
- Wu Kuan-Han H.
- Xia Rui
- Xue Chao
- Yamamoto Masayuki
- Yang Bin
- Yang Jian
- Yang Jingyun
- Yao Jie
- Yin Xianyong
- Yokota Mitsuhiro
- Yong Loo Lin School of Medicine
- Yonsei University
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- Yousri Noha A.
- Yu Ketian
- Yuan Jian-Min
- Zajac Greg J. M.
- Zeggini Eleftheria
- Zeng Lingyao
- Zhang Jifeng
- Zhang Weihua
- Zhao Jing-Hua
- Zhao Wei
- Zheng Wei
- Zhou Wei
- Zhu Xiang
- Zhu Xiaofeng
- Zilhao Nuno R.
- Zimmermann Martina E.
- Zmuda Joseph M.
- Zonderman Alan B.
- Åsvold Bjørn Olav
- Publication venue
- figshare
- Publication date
- 01/01/2023
- Field of study
Additional file 28: Table S18. Sex-participation association of the variants with significant sex-specific lipid results
Additional file 29 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
- Author
- Aadahl Mette
- Abbas Shahid
- Abecasis Goncalo
- Academy of Scientific and Innovative Research (AcSIR)
- Adair Linda S.
- Adams Hieab H. H.
- Adeyemo Adebowale A.
- Agency for Science Technology and Research (A*STAR)
- Aguilar-Salinas Carlos A.
- Akiyama Masato
- Al-Mulla Fahd
- Alexandria University
- Algebra University College
- Arbeeva Liubov
- Arctic Centre Univ. of Groningen
- Arnett Donna K.
- Asselbergs Folkert W.
- Assimes Themistocles L.
- Atlanta VA Health Care System
- Attia John
- Banas Bernhard
- Bandinelli Stefania
- Baras Aris
- Barts and The London School of Medicine and Dentistry
- Bayyana Swati
- Bechayda Sonny Augustin
- Beijing Institute for Brain Disorders
- Beijing Institute of Ophthalmology
- Benjamins Jan W.
- Bennett David A.
- Bentley Amy R.
- Berlin Institute of Health
- Beulens Joline W. J.
- Bharadwaj Dwaipayan
- Bhatti Konain Fatima
- BHF Glasgow Cardiovascular Research Centre Faculty of Medicine
- Bielak Lawrence F.
- Biino Ginevra
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- Bispebjerg and Frederiksberg Hospital
- Bjerregaard Anne A.
- Black Corri
- Boehnke Michael
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- Boomsma Dorret I.
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- Bornholms Hospital
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- Chen Zhengming
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- deCODE genetics/Amgen Inc.
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- Kim Eung Kweon
- Kim Han-Na
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- Kim Young Jin
- King Abdulaziz University
- King's College London
- Kivimaki Mika
- Klarin Derek
- Kleber Marcus E.
- Koh Woon-Puay
- Koistinen Heikki A.
- Kolcic Ivana
- Kooner Jaspal S.
- Kooperberg Charles
- Kovacs Peter
- Kraaijeveld Adriaan O.
- Kraft Peter
- Krauss Ronald M.
- Kronenberg Florian
- Kubo Michiaki
- Kullo Iftikhar J.
- Kumari Meena
- Kurbasic Azra
- Kurume University School of Medicine
- Kutalik Zoltan
- Kuusisto Johanna
- Kyoto University Graduate School of Medicine
- Kyung Hee University School of Medicine
- Kähönen Mika
- Kårhus Line L.
- Laakso Markku
- Laboratory for Financial Engineering of Laval University
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- Lange Leslie A.
- Langenberg Claudia
- Launer Lenore J.
- Le Phuong
- Lee Hyejin
- Lee Jong Young
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- Lieb Wolfgang
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- Lin Kuang
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- Linneberg Allan
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- Liu Jianjun
- Liu Jun
- Lo Ken Sin
- Local Health Unit Toscana Centro
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- Loeffler Markus
- London North West University Healthcare NHS Trust
- Long Jirong
- Loos Ruth J. F.
- Lorés-Motta Laura
- Loukola Anu
- Ltd
- Lu Xiangfeng
- Luan Jian’an
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- Lund University Diabetes Centre
- Lynch Julie A.
- Lyssenko Valeriya
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- Magnusson Patrik K. E.
- Mahajan Anubha
- Mamakou Vasiliki
- Mangino Massimo
- Manichaikul Ani
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- Marten Jonathan
- Martin Hilary C.
- Martin Lisa Warsinger
- Martin Nicholas G.
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- Millwood Iona Y.
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- Mitchell Jonathan S.
- Mitchell Paul
- Mitchell Ruth E.
- Mohlke Karen L.
- Mook-Kanamori Dennis O.
- Mori Trevor A.
- Morris Andrew P.
- Morrison Alanna C.
- MRC Epidemiology Unit
- MRC Human Genetics Unit
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- März Winfried
- Møllehave Line T.
- Nabika Toru
- Nagoya University Graduate School of Medicine
- Nakatochi Masahiro
- Nalls Mike A.
- Namjou Bahram
- Nanjing University of Chinese Medicine
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- Wild Sarah H.
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- Wilson James F.
- Wilson James G.
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- Wong Andrew
- Wong Tien-Yin
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- Wu Kuan-Han H.
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- Zeggini Eleftheria
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- Zhang Weihua
- Zhao Jing-Hua
- Zhao Wei
- Zheng Wei
- Zhou Wei
- Zhu Xiang
- Zhu Xiaofeng
- Zilhao Nuno R.
- Zimmermann Martina E.
- Zmuda Joseph M.
- Zonderman Alan B.
- Åsvold Bjørn Olav
- Publication venue
- figshare
- Publication date
- 01/01/2023
- Field of study
Additional file 29: Table S19. Comparison of sex-stratified effect sizes in the UK Biobank for BMI, waist hip ratio adjusted for BMI, alcohol use, and smoking status