Elevated temperature material properties of stainless steel reinforcing bar

Corrosion of carbon steel reinforcing bar can lead to deterioration of concrete structures, especially in regions where road salt is heavily used or in areas close to sea water. Although stainless steel reinforcing bar costs more than carbon steel, its selective use for high risk elements is cost-effective when the whole life costs of the structure are taken into account. Considerations for specifying stainless steel reinforcing bars and a review of applications are presented herein. Attention is then given to the elevated temperature properties of stainless steel reinforcing bars, which are needed for structural fire design, but have been unexplored to date. A programme of isothermal and anisothermal tensile tests on four types of stainless steel reinforcing bar is described: 1.4307 (304L), 1.4311 (304LN), 1.4162 (LDX 2101®) and 1.4362 (2304). Bars of diameter 12 mm and 16 mm were studied, plain round and ribbed. Reduction factors were calculated for the key strength, stiffness and ductility properties and compared to equivalent factors for stainless steel plate and strip, as well as those for carbon steel reinforcement. The test results demonstrate that the reduction factors for 0.2% proof strength, strength at 2% strain and ultimate strength derived for stainless steel plate and strip can also be applied to stainless steel reinforcing bar. Revised reduction factors for ultimate strain and fracture strain at elevated temperatures have been proposed. The ability of two-stage Ramberg-Osgood expressions to capture accurately the stress-strain response of stainless steel reinforcement at both room temperature and elevated temperatures is also demonstrated

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.

To further understanding of the genetic basis of type 2 diabetes (T2D) susceptibility, we aggregated published meta-analyses of genome-wide association studies (GWAS), including 26,488 cases and 83,964 controls of European, east Asian, south Asian and Mexican and Mexican American ancestry. We observed a significant excess in the directional consistency of T2D risk alleles across ancestry groups, even at SNPs demonstrating only weak evidence of association. By following up the strongest signals of association from the trans-ethnic meta-analysis in an additional 21,491 cases and 55,647 controls of European ancestry, we identified seven new T2D susceptibility loci. Furthermore, we observed considerable improvements in the fine-mapping resolution of common variant association signals at several T2D susceptibility loci. These observations highlight the benefits of trans-ethnic GWAS for the discovery and characterization of complex trait loci and emphasize an exciting opportunity to extend insight into the genetic architecture and pathogenesis of human diseases across populations of diverse ancestry

Effects of built environment morphology on wind turbine noise exposure at building façades

© 2017 Elsevier LtdWith wind farms installed in urban and suburban areas, the noise exposure of buildings is affected both by distance attenuation and the morphology of the built environment. With the aim of exploring the noise-resisting effects of built environment morphology, three kinds of typical suburban areas in the UK were sampled and noise maps were generated based upon an idealised modern wind turbine placed at various setback distances from each site. Relationships between morphological indices and building façade exposures were examined through regression analyses. Noise reduction levels of five morphological indices were given in terms of resisting wind turbine noise with different source-receiver (S-R) distances, and at different frequencies. The results show that built environment morphology has considerable effects on resisting the noise exposure of buildings and can create a quiet façade with up to 13 dBA difference to the most exposure façade. Among the five indices, building orientation is found to be most effective in resisting the noise exposure of building façades, followed by the length and shape of the building. The noise resistance effects vary by different S-R distances and differ by frequency. Four morphological indices are found to be effective in resisting noise at low frequencies, typically at 50 Hz

Acoustic and mechanical properties of luffa fiber-reinforced biocomposites

This chapter presents an overview of acoustic and mechanical behaviors of luffa fiber reinforced biocomposites. A growing number of studies are examining the composites of biodegradable fibers such as flax, hemp, kenaf and luffa due to the adverse effects of chemical materials on nature. The low cost and superior acoustic and acceptable mechanical properties of biocomposites make them very attractive for practical applications such as sound and vibration isolation. However, the acoustic and mechanical characteristics of biocomposites and their dynamic behaviors should be fully determined before considering them for practical applications. In this chapter, acoustic properties, such as sound absorption and transmission loss, and mechanical properties, such as damping and elasticity of luffa fiber reinforced composites, are presented. The variations in acoustic and mechanical properties due to different samples and manufacturing process are explored.WOS:000532438200017Scopus - Affiliation ID: 60105072Book Citation Index- ScienceArticle; Book ChapterOcak2019YÖK - 2018-1

Transthoracic coronary flow reserve and dobutamine derived myocardial function: a 6-month evaluation after successful coronary angioplasty

After percutaneous transluminal coronary angioplasty (PTCA), stress-echocardiography and gated single photon emission computerized tomography (g-SPECT) are usually performed but both tools have technical limitations. The present study evaluated results of PTCA of left anterior descending artery (LAD) six months after PTCA, by combining transthoracic Doppler coronary flow reserve (CFR) and color Tissue Doppler (C-TD) dobutamine stress. Six months after PTCA of LAD, 24 men, free of angiographic evidence of restenosis, underwent standard Doppler-echocardiography, transthoracic CFR of distal LAD (hyperemic to basal diastolic coronary flow ratio) and C-TD at rest and during dobutamine stress to quantify myocardial systolic (S(m)) and diastolic (E(m )and A(m), E(m)/A(m )ratio) peak velocities in middle posterior septum. Patients with myocardial infarction, coronary stenosis of non-LAD territory and heart failure were excluded. According to dipyridamole g-SPECT, 13 patients had normal perfusion and 11 with perfusion defects. The 2 groups were comparable for age, wall motion score index (WMSI) and C-TD at rest. However, patients with perfusion defects had lower CFR (2.11 ± 0.4 versus 2.87 ± 0.6, p < 0.002) and septal S(m )at high-dose dobutamine (p < 0.01), with higher WMSI (p < 0.05) and stress-echo positivity of LAD territory in 5/11 patients. In the overall population, CFR was related negatively to high-dobutamine WMSI (r = -0.50, p < 0.01) and positively to high-dobutamine S(m )of middle septum (r = 0.55, p < 0.005). In conclusion, even in absence of epicardial coronary restenosis, stress perfusion imaging reflects a physiologic impairment in coronary microcirculation function whose magnitude is associated with the degree of regional functional impairment detectable by C-TD

Differences in access to coronary care unit among patients with acute myocardial infarction in Rome: old, ill, and poor people hold the burden of inefficiency

BACKGROUND: Direct admission to Coronary Care Unit (CCU) on hospital arrival can be considered as a good proxy for adequate management in patients with acute myocardial infarction (AMI), as it has been associated with better prognosis. We analyzed a cohort of patients with AMI hospitalized in Rome (Italy) in 1997–2000 to assess the proportion directly admitted to CCU and to investigate the effect of patient characteristics such as gender, age, illness severity on admission, and socio-economic status (SES) on CCU admission practices. METHODS: Using discharge data, we analyzed a cohort of 9127 AMI patients. Illness severity on admission was determined using the Deyo's adaptation of the Charlson's comorbidity index, and each patient was assigned to one to four SES groups (level I referring to the highest SES) defined by a socioeconomic index, derived by the characteristics of the census tract of residence. The effect of gender, age, illness severity and SES, on risk of non-admission to CCU was investigated using a logistic regression model (OR, CI 95%). RESULTS: Only 53.9% of patients were directly admitted to CCU, and access to optimal care was more frequently offered to younger patients (OR = 0.35; 95%CI = 0.25–0.48 when comparing 85+ to >=50 years), those with less severe illness (OR = 0.48; 95%CI = 0.37–0.61 when comparing Charlson index 3+ to 0) and the socially advantaged (OR = 0.81; 95%CI = 0.66–0.99 when comparing low to high SES). CONCLUSION: In Rome, Italy, standard optimal coronary care is underprovided. It seems to be granted preferentially to the better off, even after controversial clinical criteria, such as age and severity of illness, are taken into account

Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study

Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings: This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 81·7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28–2·40], p\textless0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65–3·22], p\textless0·0001), American Society of Anesthesiologists grades 3–5 versus grades 1–2 (2·35 [1·57–3·53], p\textless0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01–2·39], p=0·046), emergency versus elective surgery (1·67 [1·06–2·63], p=0·026), and major versus minor surgery (1·52 [1·01–2·31], p=0·047). Interpretation: Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding: National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research