1,773 research outputs found

    Three-dimensional echocardiography for left ventricular quantification: fundamental validation and clinical applications

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    One of the earliest applications of clinical echocardiography is evaluation of left ventricular (LV) function and size. Accurate, reproducible and quantitative evaluation of LV function and size is vital for diagnosis, treatment and prediction of prognosis of heart disease. Early three-dimensional (3D) echocardiographic techniques showed better reproducibility than two-dimensional (2D) echocardiography and narrower limits of agreement for assessment of LV function and size in comparison to reference methods, mostly cardiac magnetic resonance (CMR) imaging, but acquisition methods were cumbersome and a lack of user-friendly analysis software initially precluded widespread use. Through the advent of matrix transducers enabling real-time three-dimensional echocardiography (3DE) and improvements in analysis software featuring semi-automated volumetric analysis, 3D echocardiography evolved into a simple and fast imaging modality for everyday clinical use. 3DE provides the possibility to evaluate the entire LV in three spatial dimensions during the complete cardiac cycle, offering a more accurate and complete quantitative evaluation the LV. Improved efficiency in acquisition and analysis may provide clinicians with important diagnostic information within minutes. The current article reviews the methodology and application of 3DE for quantitative evaluation of the LV, provides the scientific evidence for its current clinical use, and discusses its current limitations and potential future directions

    A FamĂ­lia e Educação em SaĂșde

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    O Curso de PĂłs-graduação em Atenção BĂĄsica em SaĂșde da FamĂ­lia, na modalidade a distĂąncia, em Mato Grosso do Sul, faz a opção metodolĂłgica de trabalhar de forma permanente o contexto real de prĂĄticas em que seus estudantes trabalhadores estĂŁo inseridos. O curso – que tem seu sistema instrucional baseado na Educação Ă  DistĂąncia – tem o objetivo de formar profi ssionais mĂ©dicos, enfermeiros e cirurgiĂ”es-dentistas integrantes das Equipes de SaĂșde da FamĂ­lia. É organizado por meio de um conjunto de cadernos, apresentados em diferentes mĂ­dias e utiliza ferramentas interativas. A Unidade de Ensino III deste curso intitula-se: A FamĂ­lia e Educação em SaĂșde e Ă© composta por dois mĂłdulos de aprendizagem: MĂłdulo 1 - Promoção da SaĂșde e Intersetorialidade na Abordagem Familiar. MĂłdulo 2 - A FamĂ­lia no contexto da Atenção PrimĂĄria Ă  SaĂșde. O MĂłdulo 1, Promoção da SaĂșde e Intersetorialidade na Abordagem Familiar, traz a discussĂŁo de como fazer abordagens de promoção e educação em saĂșde dirigidas ao indivĂ­duo, Ă  famĂ­lia e Ă  comunidade. O mĂłdulo estĂĄ organizado em seis seçÔes: a primeira discute a interface Promoção de SaĂșde/ Educação em SaĂșde e a infl uĂȘncia do processo histĂłrico na compreensĂŁo do binĂŽmio SaĂșde/Doença. A segunda seção apresenta a evolução do processo de educação em SaĂșde. A terceira seção traz a discussĂŁo da necessidade de realizar Promoção em SaĂșde para melhorar a qualidade de vida da população. A quarta seção traz a discussĂŁo do papel do profi ssional de saĂșde como agente facilitador no processo de Educação em SaĂșde. Na seção cinco discute-se a Educação em SaĂșde e açÔes interdisciplinares. E a seção seis mostra as tĂ©cnicas de Educação em saĂșde. O mĂłdulo tem o objetivo dar a vocĂȘ, desta forma, ferramentas para escolher a melhor estratĂ©gia de abordagem no processo de educação em saĂșde de acordo com a situação local, fatores de risco e população-alvo, alĂ©m de ajudĂĄ-lo a planejar a realização de uma proposta promotora/educadora em saĂșde. O mĂłdulo 2: A FamĂ­lia no Contexto da Atenção PrimĂĄria Ă  SaĂșde estĂĄ dividido em cinco seçÔes. A primeira seção apresenta as polĂ­ticas voltadas Ă  atenção das famĂ­lias. A segunda seção discute conceito de famĂ­lia, as funçÔes e estrutura das famĂ­lias e as transformaçÔes da famĂ­lia contemporĂąnea. A terceira seção discute as situaçÔes de vulnerabilidade a que as famĂ­lias estĂŁo expostas e apresenta as etapas para se trabalhar com famĂ­lias. A quarta seção traz as tecnologias de abordagem familiar. E, fi nalmente, a quinta seção discute as ferramentas para se realizar a abordagem familiar. Com a apresentação e discussĂŁo destes conteĂșdos vocĂȘ terĂĄ a oportunidade de fazer uma refl exĂŁo a respeito de seus conhecimentos e começar a aplicar estas ferramentas na atenção de sua população. Este mĂłdulo tem os seguintes objetivos: promover a mudança do foco de atenção das equipes de saĂșde da famĂ­lia e a atenção Ă s doenças para uma abordagem centrada no indivĂ­duo e sua famĂ­lia. Estes dois mĂłdulos sĂŁo fundamentais para que vocĂȘ tenha instrumentos efi cazes para manter e recuperar a saĂșde de sua comunidade. Efetivar o conceito que a estratĂ©gia de saĂșde da famĂ­lia apresenta Ă© muito mais amplo que atender os doentes de sua ĂĄrea. A estratĂ©gia de saĂșde da famĂ­lia sĂł cumprirĂĄ sua fi nalidade a partir do momento que sua população adscrita seja capaz de construir um modo de vida saudĂĄvel garantindo a saĂșde de todos os membros da comunidade.MINISTÉRIO DA SAÚD

    Spatial distribution of the risk of dengue fever in southeast Brazil, 2006-2007

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    Background: Many factors have been associated with circulation of the dengue fever virus and vector, although the dynamics of transmission are not yet fully understood. The aim of this work is to estimate the spatial distribution of the risk of dengue fever in an area of continuous dengue occurrence. Methods: This is a spatial population-based case-control study that analyzed 538 cases and 727 controls in one district of the municipality of Campinas, Sao Paulo, Brazil, from 2006-2007, considering socio-demographic, ecological, case severity, and household infestation variables. Information was collected by in-home interviews and inspection of living conditions in and around the homes studied. Cases were classified as mild or severe according to clinical data, and they were compared with controls through a multinomial logistic model. A generalized additive model was used in order to include space in a non-parametric fashion with cubic smoothing splines. Results: Variables associated with increased incidence of all dengue cases in the multiple binomial regression model were: higher larval density (odds ratio (OR) = 2.3 (95%CI: 2.0-2.7)), reports of mosquito bites during the day (OR = 1.8 (95%CI: 1.4-2.4)), the practice of water storage at home (OR = 2.5 (95%CI: 1.4, 4.3)), low frequency of garbage collection (OR = 2.6 (95%CI: 1.6-4.5)) and lack of basic sanitation (OR = 2.9 (95%CI: 1.8-4.9)). Staying at home during the day was protective against the disease (OR = 0.5 (95%CI: 0.3-0.6)). When cases were analyzed by categories (mild and severe) in the multinomial model, age and number of breeding sites more than 10 were significant only for the occurrence of severe cases (OR = 0.97, (95%CI: 0.96-0.99) and OR = 2.1 (95%CI: 1.2-3.5), respectively. Spatial distribution of risks of mild and severe dengue fever differed from each other in the 2006/2007 epidemic, in the study area. Conclusions: Age and presence of more than 10 breeding sites were significant only for severe cases. Other predictors of mild and severe cases were similar in the multiple models. The analyses of multinomial models and spatial distribution maps of dengue fever probabilities suggest an area-specific epidemic with varying clinical and demographic characteristics

    Search for new phenomena in final states with an energetic jet and large missing transverse momentum in pp collisions at √ s = 8 TeV with the ATLAS detector

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    Results of a search for new phenomena in final states with an energetic jet and large missing transverse momentum are reported. The search uses 20.3 fb−1 of √ s = 8 TeV data collected in 2012 with the ATLAS detector at the LHC. Events are required to have at least one jet with pT > 120 GeV and no leptons. Nine signal regions are considered with increasing missing transverse momentum requirements between Emiss T > 150 GeV and Emiss T > 700 GeV. Good agreement is observed between the number of events in data and Standard Model expectations. The results are translated into exclusion limits on models with either large extra spatial dimensions, pair production of weakly interacting dark matter candidates, or production of very light gravitinos in a gauge-mediated supersymmetric model. In addition, limits on the production of an invisibly decaying Higgs-like boson leading to similar topologies in the final state are presente

    Observation of associated near-side and away-side long-range correlations in √sNN=5.02  TeV proton-lead collisions with the ATLAS detector

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    Two-particle correlations in relative azimuthal angle (Δϕ) and pseudorapidity (Δη) are measured in √sNN=5.02  TeV p+Pb collisions using the ATLAS detector at the LHC. The measurements are performed using approximately 1  Όb-1 of data as a function of transverse momentum (pT) and the transverse energy (ÎŁETPb) summed over 3.1<η<4.9 in the direction of the Pb beam. The correlation function, constructed from charged particles, exhibits a long-range (2<|Δη|<5) “near-side” (Δϕ∌0) correlation that grows rapidly with increasing ÎŁETPb. A long-range “away-side” (Δϕ∌π) correlation, obtained by subtracting the expected contributions from recoiling dijets and other sources estimated using events with small ÎŁETPb, is found to match the near-side correlation in magnitude, shape (in Δη and Δϕ) and ÎŁETPb dependence. The resultant Δϕ correlation is approximately symmetric about π/2, and is consistent with a dominant cos⁥2Δϕ modulation for all ÎŁETPb ranges and particle pT
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