64 research outputs found
Techniques of blood group desensitization
- Author
- Publication venue
- DigitalCommons@UNMC
- Publication date
- 01/01/1958
- Field of study
Variability in the analysis of a single neuroimaging dataset by many teams
- Author
- Adcock A
- Avesani P
- Baczkowski B
- Bajracharya A
- Bakst L
- Ball S
- Barilari M
- Bault N
- Beaton D
- Beitner J
- Benoit R
- Berkers R
- Bhanji J
- Biswal B
- Bobadilla-Suarez S
- Bortolini T
- Bottenhorn K
- Botvinik-Nezer R
- Bowring A
- Braem S
- Brooks H
- Brudner E
- Calderon C
- Camerer CF
- Camilleri J
- Castrellon J
- Cecchetti L
- Cieslik E
- Cole Z
- Collignon O
- Cox R
- Cunningham W
- Czoschke S
- Dadi K
- Davis C
- De Luca A
- Delgado M
- Demetriou L
- Dennison J
- Di X
- Dickie E
- Dobryakova E
- Donnat C
- Dreber A
- Dukart J
- Duncan NW
- Durnez J
- Eed A
- Eickhoff S
- Erhart A
- Fontanesi L
- Fricke GM
- Galvan A
- Gau R
- Genon S
- Glatard T
- Glerean E
- Goeman J
- Golowin S
- GonzĂĄlez-GarcĂa C
- Gorgolewski K
- Grady C
- Green M
- Guassi Moreira J
- Guest O
- Hakimi S
- Hamilton JP
- Hancock R
- Handjaras G
- Harry B
- Hawco C
- Herholz P
- Herman G
- Heunis S
- Hoffstaedter F
- Hogeveen J
- Holmes S
- Holzmeister F
- Hu C-P
- Huber J
- Huettel S
- Hughes M
- Iacovella V
- Iordan A
- Isager P
- Isik AI
- Iwanir R
- Jahn A
- Johannesson M
- Johnson M
- Johnstone T
- Joseph M
- Juliano A
- Kable J
- Kassinopoulos M
- Kirchler M
- Koba C
- Kong X-Z
- Koscik T
- Kucukboyaci NE
- Kuhl B
- Kupek S
- Laird A
- Lamm C
- Langner R
- Lauharatanahirun N
- Lee H
- Lee S
- Leemans A
- Leo A
- Lesage E
- Li F
- Li M
- Lim PC
- Lintz E
- Liphardt S
- Losecaat Vermeer A
- Love B
- Mack M
- Malpica N
- Marins T
- Maumet C
- McDonald K
- McGuire J
- Melero H
- Meyer B
- Meyer K
- Mihai P
- Mitsis G
- Moll J
- Mumford JA
- MĂ©ndez Leal A
- Nichols TE
- Nielson D
- Nilsonne G
- Notter M
- Olivetti E
- Onicas A
- Papale P
- Patil K
- Peelle JE
- Pischedda D
- Poldrack RA
- Poline J-B
- Prystauka Y
- PĂ©rez A
- Ray S
- Reuter-Lorenz P
- Reynolds R
- Ricciardi E
- Rieck J
- Rodriguez-Thompson A
- Romyn A
- Salo T
- Samanez-Larkin G
- Sanz-Morales E
- Schlichting M
- Schonberg T
- Schultz D
- Shen Q
- Sheridan M
- Shiguang F
- Silvers J
- Skagerlund K
- Smith A
- Smith D
- Sokol-Hessner P
- Steinkamp S
- Tashjian S
- Thirion B
- Thorp J
- Tinghög G
- Tisdall L
- Tompson S
- Toro-Serey C
- Torre J
- Tozzi L
- Truong V
- Turella L
- vanât Veer AE
- Verguts T
- Vettel J
- Vijayarajah S
- Vo K
- Wall M
- Weeda WD
- Weis S
- White D
- Wisniewski D
- Xifra-Porxas A
- Yearling E
- Yoon S
- Yuan R
- Yuen K
- Zhang L
- Zhang X
- Zosky J
- Publication venue
- BioRxiv
- Publication date
- 01/01/2019
- Field of study
Data analysis workflows in many scientific domains have become increasingly complex and flexible. To assess the impact of this flexibility on functional magnetic resonance imaging (fMRI) results, the same dataset was independently analyzed by 70 teams, testing nine ex-ante hypotheses. The flexibility of analytic approaches is exemplified by the fact that no two teams chose identical workflows to analyze the data. This flexibility resulted in sizeable variation in hypothesis test results, even for teams whose statistical maps were highly correlated at intermediate stages of their analysis pipeline. Variation in reported results was related to several aspects of analysis methodology. Importantly, meta-analytic approaches that aggregated information across teams yielded significant consensus in activated regions across teams. Furthermore, prediction markets of researchers in the field revealed an overestimation of the likelihood of significant findings, even by researchers with direct knowledge of the dataset. Our findings show that analytic flexibility can have substantial effects on scientific conclusions, and demonstrate factors related to variability in fMRI. The results emphasize the importance of validating and sharing complex analysis workflows, and demonstrate the need for multiple analyses of the same data. Potential approaches to mitigate issues related to analytical variability are discussed
Variability in the analysis of a single neuroimaging dataset by many teams
- Author
- Adcock A
- Avesani P
- Baczkowski B
- Bajracharya A
- Bakst L
- Ball S
- Barilari M
- Bault N
- Beaton D
- Beitner J
- Benoit R
- Berkers R
- Bhanji J
- Biswal B
- Bobadilla-Suarez S
- Bortolini T
- Bottenhorn K
- Botvinik-Nezer R
- Bowring A
- Braem S
- Brooks H
- Brudner E
- Calderon C
- Camerer CF
- Camilleri J
- Castrellon J
- Cecchetti L
- Cieslik E
- Cole Z
- Collignon O
- Cox R
- Cunningham W
- Czoschke S
- Dadi K
- Davis C
- De Luca A
- Delgado M
- Demetriou L
- Dennison J
- Di X
- Dickie E
- Dobryakova E
- Donnat C
- Dreber A
- Dukart J
- Duncan NW
- Durnez J
- Eed A
- Eickhoff S
- Erhart A
- Fontanesi L
- Fricke GM
- Galvan A
- Gau R
- Genon S
- Glatard T
- Glerean E
- Goeman J
- Golowin S
- GonzĂĄlez-GarcĂa C
- Gorgolewski K
- Grady C
- Green M
- Guassi Moreira J
- Guest O
- Hakimi S
- Hamilton JP
- Hancock R
- Handjaras G
- Harry B
- Hawco C
- Herholz P
- Herman G
- Heunis S
- Hoffstaedter F
- Hogeveen J
- Holmes S
- Holzmeister F
- Hu C-P
- Huber J
- Huettel S
- Hughes M
- Iacovella V
- Iordan A
- Isager P
- Isik AI
- Iwanir R
- Jahn A
- Johannesson M
- Johnson M
- Johnstone T
- Joseph M
- Juliano A
- Kable J
- Kassinopoulos M
- Kirchler M
- Koba C
- Kong X-Z
- Koscik T
- Kucukboyaci NE
- Kuhl B
- Kupek S
- Laird A
- Lamm C
- Langner R
- Lauharatanahirun N
- Lee H
- Lee S
- Leemans A
- Leo A
- Lesage E
- Li F
- Li M
- Lim PC
- Lintz E
- Liphardt S
- Losecaat Vermeer A
- Love B
- Mack M
- Malpica N
- Marins T
- Maumet C
- McDonald K
- McGuire J
- Melero H
- Meyer B
- Meyer K
- Mihai P
- Mitsis G
- Moll J
- Mumford JA
- MĂ©ndez Leal A
- Nichols TE
- Nielson D
- Nilsonne G
- Notter M
- Olivetti E
- Onicas A
- Papale P
- Patil K
- Peelle JE
- Pischedda D
- Poldrack RA
- Poline J-B
- Prystauka Y
- PĂ©rez A
- Ray S
- Reuter-Lorenz P
- Reynolds R
- Ricciardi E
- Rieck J
- Rodriguez-Thompson A
- Romyn A
- Salo T
- Samanez-Larkin G
- Sanz-Morales E
- Schlichting M
- Schonberg T
- Schultz D
- Shen Q
- Sheridan M
- Shiguang F
- Silvers J
- Skagerlund K
- Smith A
- Smith D
- Sokol-Hessner P
- Steinkamp S
- Tashjian S
- Thirion B
- Thorp J
- Tinghög G
- Tisdall L
- Tompson S
- Toro-Serey C
- Torre J
- Tozzi L
- Truong V
- Turella L
- vanât Veer AE
- Verguts T
- Vettel J
- Vijayarajah S
- Vo K
- Wall M
- Weeda WD
- Weis S
- White D
- Wisniewski D
- Xifra-Porxas A
- Yearling E
- Yoon S
- Yuan R
- Yuen K
- Zhang L
- Zhang X
- Zosky J
- Publication venue
- BioRxiv
- Publication date
- 15/11/2019
- Field of study
Data analysis workflows in many scientific domains have become increasingly complex and flexible. To assess the impact of this flexibility on functional magnetic resonance imaging (fMRI) results, the same dataset was independently analyzed by 70 teams, testing nine ex-ante hypotheses. The flexibility of analytic approaches is exemplified by the fact that no two teams chose identical workflows to analyze the data. This flexibility resulted in sizeable variation in hypothesis test results, even for teams whose statistical maps were highly correlated at intermediate stages of their analysis pipeline. Variation in reported results was related to several aspects of analysis methodology. Importantly, meta-analytic approaches that aggregated information across teams yielded significant consensus in activated regions across teams. Furthermore, prediction markets of researchers in the field revealed an overestimation of the likelihood of significant findings, even by researchers with direct knowledge of the dataset. Our findings show that analytic flexibility can have substantial effects on scientific conclusions, and demonstrate factors related to variability in fMRI. The results emphasize the importance of validating and sharing complex analysis workflows, and demonstrate the need for multiple analyses of the same data. Potential approaches to mitigate issues related to analytical variability are discussed
IMPACT-Global Hip Fracture Audit: Nosocomial infection, risk prediction and prognostication, minimum reporting standards and global collaborative audit. Lessons from an international multicentre study of 7,090 patients conducted in 14 nations during the COVID-19 pandemic
- Author
- Abdul-Jabar Hani
- Abu-Rajab Rashid
- Abugarja Ahmed
- Adam Karen
- Aguado HernĂĄndez HĂ©ctor J.
- Améstica Lazcano Gedeón
- Anderson Sarah
- Ansar Mahmood
- Antrobus Jonathan
- AragĂłn Achig Esteban Javier
- Archunan Maheswaran
- Arrieta Salinas Mirentxu
- Ashford-Wilson Sarah
- Assens Gibert Cristina
- Athanasopoulou Katerina
- Awadelkarim Mohamed
- Baird Stuart
- Bajada Stefan
- Balakrishnan Shobana
- Balasubramanian Sathishkumar
- Ballantyne James A.
- Barkham Benjamin
- Barmpagianni Christina
- Barres-Carsi Mariano
- Barrett Sarah
- Baskaran Dinnish
- Bell Jean
- Bell Katrina
- Bell Stuart
- Bellelli Giuseppe
- Benchimol Javier Alberto
- Boietti Bruno Rafael
- Boswell Sally
- Braile Adriano
- Brennan Caitlin
- Brent Louise
- Brooke Ben
- Bruno Gaetano
- Burahee Abdus
- Burns Shirley
- BĂĄrcena Goitiandia Leopoldo
- CalabrĂČ Giampiero
- Campbell Lucy
- Carabelli Guido Sebastian
- Carnegie Carol
- Carretero Cristobal Guillermo
- Caruana Ethan
- Cassinello Ogea M. a ConcepciĂłn
- Castellanos Robles Juan
- Castillon Pablo
- Cecere Antonio Benedetto
- Chakrabarti Anil
- Chen Ping
- Clarke Jon V.
- Clement Nicholas D.
- Collins Grace
- Corrales Cardenal Jorge E.
- Corsi Maurizio
- Craxford Simon
- Crooks Melissa
- Cuarental-GarcĂa Javier
- Cuthbert Rory
- CĂłzar Adelantado Gara MarĂa
- Dall Graham
- Daskalakis Ioannis
- De Cicco Annalisa
- Demaria Pablo
- Dereix John
- Diana de la Fuente de Dios
- Dinamarca Montecinos José Luis
- Do Le Ha Phuong
- Donoso Coppa Juan Pablo
- Drosos Georgios
- Duckworth Andrew D.
- Duffy Andrew
- DĂaz JimĂ©nez Julian
- East Jamie
- Eastwood Deborah
- Elbahari Hassan
- Elias de Molins Peña Carmen
- Elmamoun Mamoun
- Emmerson Ben
- Escobar SĂĄnchez Daniel
- Faimali Martina
- Farrow Luke
- FarrĂ©-MercadĂ© Maria VictĂČria
- Fayez Almari
- Fell Adam
- Fenner Christopher
- Ferguson David
- Finlayson Louise
- Flores GĂłmez Aldo
- Freeman Nicholas
- French Jonathan
- Gabardo Calvo Santiago
- Gagliardo Nicola
- Garcia Albiñana Joan
- GarcĂa Cruz Guillermo
- GarcĂa de CortĂĄzar AntolĂn Unai
- GarcĂa Virto Virginia
- Gealy Sophie
- Gil Caballero Sandra Marcela
- Gill Moneet
- GonzĂĄlez GonzĂĄlez MarĂa Soledad
- Gopireddy Rajesh
- Guntley Diane
- Gurung Binay
- GuzmĂĄn Rosales Guadalupe
- Haddad Nedaa
- Hafeez Mahum
- Hall Andrew J.
- Haller Petra
- Halligan Emer
- Hamid Hytham K. S.
- Hardie John
- Hawker Imogen
- Helal Amr
- Herrera Cruz Mariana
- Herreros Ruiz-Valdepeñas Ruben
- Horton James
- Howells Sean
- Howieson Alan
- Hughes Luke
- Hurtado Ortega Ana
- Huxley Peter
- HĂŒnicken Torrez Flavia Lorena
- Ilahi Nida
- Iliadis Alexis
- Inman Dominic
- Jadhao Piyush
- Jandoo Rajan
- Jawad Lucy
- Jayatilaka Malwattage Lara Tania
- Jenkins Paul J.
- Jeyapalan Rathan
- Johansen Antony
- Johnson David
- Johnston Andrew
- Joseph Sarah
- Kapoor Siddhant
- Karagiannidis Georgios
- Karanam Krishna Saga
- Kattakayam Freddy
- Konarski Alastair
- Kontakis Georgios
- Labrador HernĂĄndez Gregorio
- Lancaster Victoria
- Landi Giovanni
- Le Brian
- Liew Ignatius
- Logishetty Kartik
- Lopez Marquez Andrew Carlomaria Daniel
- Lopez Judit
- Lum Joann
- MacLullich Alasdair MJ.
- Macpherson Gavin J.
- Madan Suvira
- Mahroof Sabreena
- Malik-Tabassum Khalid
- Mallina Ravi
- Maqsood Afnan
- Marson Ben
- Martin Legorburo M José
- Martin-Perez Encarna
- Martinez Martin Javier
- MartĂnez JimĂ©nez Tania
- Mayne Alistair
- Mayor Amy
- McAlinden Gavan
- McDonald Lorna
- McIntyre Joshua
- McKay Pamela
- McKean Greg
- McLean Lucille
- McShane Heather
- Medici Antonio
- Meeke Chelsea
- Meldrum Evonne
- Mendez Mijail
- Mercer Scott
- Merino Perez Josu
- Mesa-LamprĂ© MarĂa-Pilar
- Mighton Shuna
- Milne Kirsty
- Mohamed Yaseen Muhammed
- Moppett Iain
- Mora Jesus
- Morales-Zumel Sira
- Moreno Fenoll Irene Blanca
- Mousa Adham
- Murray Alastair W.
- Murray Elspeth V.
- Nair Radhika
- Neary Fiona
- Negri Giacomo
- Negus Oliver
- Newham-Harvey Fiona
- Ng Nigel
- Nightingale Jess
- Noor Mohamed Anver Sumiya
- Nunag Perrico
- O'Hare Matthew
- Ojeda-Thies Cristina
- Ollivere Ben
- Ortés Gómez Raquel
- Owens AnneMarie
- Page Siobhan
- Palloni Valentina
- Panagiotopoulos Andreas
- Panagiotopoulos Elias
- Panesar Paul
- Papadopoulos Antonios
- Pareja Sierra Teresa
- Park Chang
- Parwaiz Hammad
- Paterson-Byrne Paul
- Patton Sam
- Pearce Jack
- Pellegrino Achille
- Pezzella Raffaele
- Phadnis Ashish
- Pinder Charlotte
- Piper Danielle
- Porter Marina
- Powell-Bowns Matilda
- Prieto MartĂn RocĂo
- Probert Annabel
- PĂšrez Cuellar Arturo
- Ramesh Ashwanth
- RamĂrez de Arellano Manuel Vicente MejĂa
- Renton Duncan
- Rickman Stephen
- Robertson Alastair
- Roche Albero Adrian
- Rodrigo Verguizas José Alberto
- RodrĂguez Couso Myriam
- Rooney Joanna
- Saldaña-DĂaz Andres
- Santulli Adriano
- Sanz PĂ©rez Marta Isabel
- Sarraf Khaled M.
- Scarsbrook Christine
- Scott Chloe E. H.
- Scott Jennifer
- Shah Sachi
- Sharaf Sharief
- Sharma Sidharth
- Shirley Denise
- Siano Antonio
- Simpson James
- Singh Abhinav
- Singh Amit
- Sinnett Tim
- Sisodia Gurudatt
- Smith Philomena
- Sophena Bert Eugenia
- Spyridon Papagiannis
- Steel Michael
- Stewart Avril
- Stewart Claire
- Sugand Kapil
- Sullivan Niall
- Sweeting Lauren
- Symes Michael
- SĂĄez-LĂłpez Pilar
- Tan Dylan Jun Hao
- Tancredi Francesco
- Tatani Irini
- Thomas Philip
- Thomson Fraser
- Toner Niamh S.
- Tong Anna
- Toro Antonio
- Toro Giuseppe
- Tosounidis Theodoros
- Tottas Stylianos
- Trinidad Leo Andrea
- Tucker Damien
- Vemulapalli Krishna
- Ventura Garces Diego
- Vernon Olivia Katherine
- Viveros Garcia Juan Carlos
- Ward Alex
- Ward Kirsty
- Watson Kate
- Weerasuriya Thisara
- White Tim O.
- Wickramanayake Udara
- Wilkinson Hannah
- Windley Joseph
- Wood Janet
- Wynell-Mayow William
- Zatti Giovanni
- Zeiton Moez
- ZurrĂłn Lobato Miriam
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2022
- Field of study
Evaluation of individual and ensemble probabilistic forecasts of COVID-19 mortality in the United States
- Author
- Abbott Sam
- Abernethy Neil F.
- Adee Madeline
- Adhikari Bijaya
- Arik Sercan O.
- Asplund John
- Ayer Turgay
- Baccam Prasith
- Baek Jackie
- Baer Thomas M.
- Ban Xuegang
- Bannur Nayana
- Barber Ryan
- Baxter Arden
- Ben-Nun Michal
- Bennouna Mohammed Amine
- Bertsimas Dimitris
- Bian Jiang
- Biegel Hannah
- Bien Jacob
- Biggerstaff Matthew
- Bosse Nikos I.
- Bracher Johannes
- Brennen Andrea
- Brooks Logan
- Burant John C.
- Cao Wei
- Castro Rivadeneira Alvaro J.
- Castro Lauren
- Cavany Sean
- Cegan Jeffrey C.
- Celi Leo A.
- Chen Jinghui
- Chen Samuel
- Chen YangQuan
- Chhatwal Jagpreet
- Chinazzi Matteo
- Corsetti Sabrina M.
- Cramer Estee Y.
- Cui Jiaming
- Dahan Maytal
- Dalgic Ozden O.
- Davis Jessica T.
- Della Penna Nicolas
- Dent Juan
- DesRoches David
- Dettwiller Ian D.
- Deva Ayush
- Drake John M.
- Dusenberry Mike
- Eisenberg Marisa C.
- England William P.
- Epshteyn Arkady
- España Guido
- Fairchild Geoffrey
- Falb Karl
- Faraone Stephen V.
- Farias Vivek
- Farthing Matthew W.
- Forli Pedro
- Fox Spencer
- Funk Sebastian
- Gaither Kelly
- Gakidou Emmanuela
- Gao Lei
- Gao Liyao
- Gao Zhifeng
- Gardner Lauren
- George Glover E.
- Georgescu Andreea
- Gerding Aaron
- Gibson Graham Casey
- Gneiting Tilmann
- Grantz Kyra H.
- Green Alden
- Gu Quanquan
- Gu Youyang
- Gu Zhiling
- Guertin Stephanie L.
- Guo Lihong
- Gurung Heidi L.
- Hamory Bruce
- Hay Simon I.
- Hellewell Joel
- Hess Jonathan
- Hill Alison L.
- Ho Lam Si Tung
- Hong Qi-Jun
- House Katie H.
- Hu Addison J.
- Huang Yitao
- Huang Yuxin
- Hulme-Lowe Christopher
- Hunter Robert H.
- Huynh Huong
- Jadbabaie Ali
- Jahja Maria
- Jain Sansiddh
- Jayawardena Dasuni
- Jin Xiaoyong
- Johansson Michael A.
- Kalantari Rahi
- Kaminsky Joshua
- Kaminsky Kathryn
- Kanal Elli
- Kanji Abdul H.
- Karlen Dean
- Keegan Lindsay T.
- Keskinocak Pinar
- Khandelwal Ayush
- Kim Myungjin
- Kinsey Matt
- Kong Stanley
- Koyluoglu Ugur
- Kraus Andrea
- Kraus David
- Kulkarni Mihir
- Kyriakides Christina
- Lachmann Michael
- Ladd Mary A.
- Lafferty Brandon
- Lauer Stephen A.
- Lavista Ferres Juan
- Le Khoa
- Le Long T.
- Lee Elizabeth C.
- Lega Joceline
- Leis Helen
- Lemaitre Joseph C.
- Lessler Justin
- Levi Retsef
- Li Chaozhuo
- Li Chun-Liang
- Li Michael L.
- Li Xinyi
- Lim Steve
- Linas Benjamin P.
- Linkov Igor
- Liu Tie-Yan
- Lopez Velma K.
- Ma Yian
- Marshall Maximilian
- Martin Emily T.
- Mayo Michael L.
- McCauley Ella
- McConnell Steve
- McDonald Daniel
- Meakin Sophie R.
- Meredith Hannah R.
- Merugu Srujana
- Meyers Lauren Ancel
- Michaud Isaac
- Milliken John
- Moloney Michael
- Moore Sean
- Morgan James
- Morley Christopher P.
- Mu Kunpeng
- Mueller Peter
- Mullany Luke C.
- Murray Chris
- Myers Robert L.
- MĂŒhlemann Anja
- Nagraj V. P.
- Narasimhan Balasubramanian
- Niemi Jarad
- Nirgudkar Ninad
- Nixon Kristen
- Nze-Ndong David
- Oidtman Rachel
- Oruc Buse Eylul
- Osthus Dave
- Ozcan Gokce
- OâDea Eamon B.
- Pagano Robert
- Parno Matthew D.
- Pastore y Piontti Ana
- Pei Sen
- Perakis Georgia
- Perez-Saez Javier
- Perkins Alex
- Pfister Tomas
- Pigott David
- Piwonka Noah
- Politsch Collin
- Prakash B. Aditya
- Rainwater-Lovett Kaitlin
- Rajanala Samyak
- Raval Alpan
- Ravi Matt
- Ray Evan L.
- Reich Nicholas G.
- Reiner Robert C.
- Riley Pete
- Riley Steven
- RodrĂguez Alexander
- Rowland Michael A.
- Rumack Aaron
- Salekin Asif
- Sarker Arnab
- Sava Dario
- Schrader Chris
- Schwarz Tom
- Scott James G.
- Serban Nicoleta
- Shah Apurv
- Shah Devavrat
- Shah Sam
- Shakhnovich Elizabeth
- Shaman Jeffrey
- Sheldon Daniel
- Sherratt Katharine
- Shi Yunfeng
- Shin Lauren
- Shingi Siddhant
- Siegel Daniel
- Simon Noah
- Singhvi Divya
- Sinha Deeksha
- Sinha Rajarishi
- Skali Lami Omar
- Slayton Rachel B.
- Smith Claire P.
- Soni Saksham
- Spantidakis Ioannis
- Spatz Ryan
- Srivastava Ajitesh
- Stage Steven A.
- Stark Ariane
- Stiefeling Chris
- Suchoski Bradley T.
- Sundar Saketh
- Tabassum Anika
- Tallaksen Katharine
- Tazi Bouardi Hamza
- Tec Mauricio
- Thayaparan Leann
- Tibshirani Rob
- Tibshirani Ryan J.
- Tiwari Avtansh
- Tran Quoc T.
- Truelove Shaun A.
- Trump Benjamin D.
- Tsai Thomas
- Tsiourvas Asterios
- Turner Stephen D.
- Turtle James A.
- van de Walle Axel
- Ventura Valerie
- Vespignani Alessandro
- Walker Jo W.
- Walraven Robert
- Wang Dongliang
- Wang Guannan
- Wang Lily
- Wang Lingxiao
- Wang Qinxia
- Wang Yijin
- Wang Yu-Xiang
- Wang Yuanjia
- Wang Yueying
- Wasserman Larry
- Wattanachit Nutcha
- White Jerome
- Wilde Joshua
- Wilkinson Barrie
- Wills Josh
- Wilson Shelby
- Wolfinger Russ
- Wong Alexander
- Woody Spencer
- Wu Dongxia
- Xiao Jade
- Xie Jiajia
- Xie Shanghong
- Xie Xing
- Xiong Xinyue
- Xu Pan
- Yamana Teresa K.
- Yan Xifeng
- Yoder Nate
- Yoon Jinsung
- Yu Rose
- Yu Shan
- Zeng Donglin
- Zhang Leyou
- Zhang Shun
- Zhang Weitong
- Zhang-James Yanli
- Zhao Yanting
- Zheng Andrew
- Zheng Shun
- Zhou Mingyuan
- Zorn Martha W.
- Zou Difan
- Publication venue
- National Academy of Sciences
- Publication date
- 04/05/2022
- Field of study
Short-term probabilistic forecasts of the trajectory of the COVID-19 pandemic in the United States have served as a visible and important communication channel between the scientific modeling community and both the general public and decision-makers. Forecasting models provide specific, quantitative, and evaluable predictions that inform short-term decisions such as healthcare staffing needs, school closures, and allocation of medical supplies. Starting in April 2020, the US COVID-19 Forecast Hub (https://covid19forecasthub.org/) collected, disseminated, and synthesized tens of millions of specific predictions from more than 90 different academic, industry, and independent research groups. A multimodel ensemble forecast that combined predictions from dozens of groups every week provided the most consistently accurate probabilistic forecasts of incident deaths due to COVID-19 at the state and national level from April 2020 through October 2021. The performance of 27 individual models that submitted complete forecasts of COVID-19 deaths consistently throughout this year showed high variability in forecast skill across time, geospatial units, and forecast horizons. Two-thirds of the models evaluated showed better accuracy than a naĂŻve baseline model. Forecast accuracy degraded as models made predictions further into the future, with probabilistic error at a 20-wk horizon three to five times larger than when predicting at a 1-wk horizon. This project underscores the role that collaboration and active coordination between governmental public-health agencies, academic modeling teams, and industry partners can play in developing modern modeling capabilities to support local, state, and federal response to outbreaks
The United States COVID-19 Forecast Hub dataset
- Author
- Abbott Sam
- Abu-Mostafa Yaser
- Adee Madeline
- Adhikari Bijaya
- Adiga Aniruddha
- Arik Sercan O.
- Asplund John
- Ayer Turgay
- Baccam Prasith
- Baek Jackie
- Baer Thomas M.
- Ban Xuegang
- Bannur Nayana
- Barber Ryan
- Bathwal Rahil
- Baxter Arden
- Bejar BenjamĂn
- Belov Artur A.
- Ben-Nun Michal
- Bennouna Amine
- Berlin Abraham
- Bertsimas Dimitris
- Bhatia Sangeeta
- Bian Jiang
- Biegel Hannah
- Bien Jacob
- Biggerstaff Matthew
- Bosch Jurgen
- Bosse Nikos I.
- Bouardi Hamza Tazi
- Bracher Johannes
- Brennen Andrea
- Brenner Michael
- Brooks Logan
- Budzinski Jozef
- Burant John C.
- Cao Duy
- Cao Wei
- Castro Lauren
- Cavany Sean
- Cegan Jeffrey C.
- Celi Leo A.
- Chang Nicholas A.
- Chattopadhyay Ishanu
- Chen Jinghui
- Chen Samuel
- Chen YangQuan
- Chen Ye
- Chen Yixian
- Chhatwal Jagpreet
- Chiang Wen-Hao
- Chinazzi Matteo
- Chintanippu Krishna
- Chitta Pavan
- Cho Jae H.
- Choirat Christine
- Chow Carson C.
- Coram Marc
- Cornell Matthew
- Corsetti Sabrina M.
- Cramer Estee Y.
- Cui Jiaming
- Dahan Maytal
- Dalgic Ozden O.
- Davis Jessica T.
- DesRoches David
- Dettwiller Ian D.
- Deva Ayush
- Drake John M.
- Dusenberry Mike
- Edwards Jessie K.
- Eisenberg Marisa C.
- England William P.
- Epshteyn Arkady
- Erickson Anne
- España Guido
- Fairchild Geoffrey
- Falb Karl
- Faraone Stephen V.
- Farias Vivek
- Farthing Matthew W.
- Ferres Juan Lavista
- Flahault Antoine
- Fong Chung-Yan
- Forli Pedro
- Fox Spencer
- Funk Sebastian
- Gaikedu Emmanuela
- Gaither Kelly
- Galasso Joseph
- Gandhi Parth D.
- Gao Junyi
- Gao Lei
- Gao Liyao
- Gao Zhifeng
- Gardner Lauren
- George Glover E.
- Georgescu Andreea
- Gerding Aaron
- Gerkin Richard C.
- Gibson Graham Casey
- Glass Lucas
- Gneiting Tilmann
- Goel Sumit
- Gowda Jethin
- Grantz Kyra H.
- Green Alden
- Gu Quanquan
- Gu Youyang
- Gu Zhiling
- Guertin Stephanie L.
- Guo Lihong
- Gurung Heidi L.
- Hamory Bruce
- Hay Simon
- Hellewell Joel
- Hess Jonathan
- Hill Alison L.
- Hlavacek William
- Ho Lam
- Hong Qi-Jun
- House Katie
- Hu Addison J.
- Huang Yi
- Huang Yitao
- Huang Yuxin
- Hulme-Lowe Christopher
- Hulse Juan Dent
- Hunter Robert H.
- Hurt Benjamin
- Hussain Fazle
- Huynh Huong
- Ibrahim Mark
- Ivy Julie S.
- Jadbabaie Ali
- Jahja Maria
- Jain Chaman
- Jain Chandini
- Jain Sansiddh
- Jayawardena Dasuni
- Jin Qixuan
- Jin Xiaoyong
- Jivane Viresh
- Jo Areum
- Jo HyeongChan
- Johansson Michael A.
- Joshi Keya
- Kalantari Rahi
- Kaminsky Joshua
- Kaminsky Kathryn
- Kanal Elli
- Kanji Abdul Hannan
- Karimzadeh Morteza
- Karlen Dean
- Keegan Lindsay T.
- Keskinocak Pinar
- Khan Zeina
- Khandelwal Ayush
- Khurana Ankita
- Kim Juhyun
- Kim Myungjin
- Kinsey Matt
- Klein Ellen
- Koyluoglu Ugur
- Kraus Andrea
- Kraus David
- Krymova Ekaterina
- Kulkarni Mihir
- Kulkarni Pranav
- Kumar Ajay
- Kyriakides Christina
- Lachmann Michael
- Lacroix Timothee
- Ladd Mary A.
- Lafferty Brandon
- Lakhani Anshul
- Lami Omar Skali
- Lauer Stephen A.
- Le Khoa
- Le Long T.
- Le Matthew
- Lee Elizabeth C.
- Lee Gavin
- Lega Joceline
- Leis Helen
- Lemaitre Joseph C.
- Lessler Justin
- Levi Retsef
- Lewis Bryan
- Li Chaozhuo
- Li Chun-Liang
- Li Michael L.
- Li Xinyi
- Liao Jason
- Lim Steve
- Lin Yen Ting
- Linas Benjamin P.
- Linkov Igor
- Liu Tie-Yan
- Lopez Velma K.
- Lu Guoqing
- Lucas Benjamin
- Lushtak Samuel M.
- Ma Yian
- Mallela Abhishek
- Manetti Elisa
- Mann Ethan
- Marathe Madhav
- Marshall Maximilian
- Martin Emily T.
- Mayo Michael L.
- Mayorga Maria E.
- McAndrew Thomas
- McCauley Ella
- McConnell Steve
- McDonald Daniel
- Meakin Sophie R.
- Mehrotra Prakhar
- Mele Jessica
- Meredith Hannah R.
- Merugu Srujana
- Meyers Lauren Ancel
- Michaud Isaac
- Miller Ely
- Milliken John
- Mody Vidhi
- Mody Vrushti
- Mohler George
- Moloney Michael
- Moore Sean
- Morgan James
- Morley Christopher P.
- Mu Kunpeng
- Mueller Peter
- Mullany Luke C.
- Murray Chris
- Myers Robert L.
- MĂŒhlemann Anja
- Nagraj V. P.
- Namigai Kristen
- Narasimhan Balasubramanian
- Ndong David Nze
- Neumann Jacob
- Ngo Thoai
- Nickel Maximilian
- Niemi Jarad
- Nirgudkar Ninad
- Nixon Kristen
- Nouvellet Pierre
- Obozinski Guillaume
- Oidtman Rachel
- Oruc Buse Eylul
- Osthus Dave
- Ozcan Gokce
- OâDea Eamon B.
- Pagano Robert
- Panaggio Mark J.
- Parno Matthew D.
- Pasumarty Sujitha
- Peddireddy Akhil Sai
- Penna Nicolas D.
- Perakis Georgia
- Perez-Saez Javier
- Perkins Alex
- Pfeiffer Ruth
- Pfister Tomas
- Pigott David
- Piontti Ana Pastore y
- Piriya Matthew
- Piwonka Noah
- Politsch Collin
- Popken Max
- Porebski Przemyslaw
- Posner Richard
- Prakash B. Aditya
- Qian Cheng
- Rainwater-Lovett Kaitlin
- Rajanala Samyak
- Raval Alpan
- Ravi Matt
- Ray Evan L.
- Reich Nicholas G.
- Reich Nicholas G.
- Reiner Robert C.
- Riley Pete
- Riley Steven
- Rivadeneira Alvaro J. Castro
- RodrĂguez Alexander
- Romberg Justin
- Rosenstrom Erik T.
- Rowland Michael A.
- Rumack Aaron
- Sagun Levent
- Salekin Asif
- Sarker Arnab
- Schrader Chris
- Schwarz Tom
- Scott James G.
- Sen Pei
- Serban Nicoleta
- Shah Apurv
- Shah Devavrat
- Shah Sam
- Shakhnovich Elizabeth
- Shaman Jeffrey
- Sharma Rakshith
- Sheldon Daniel
- Sherratt Katharine
- Shi Yunfeng
- Shin Lauren
- Shingi Siddhant
- Shrivastav Monika
- Siegel Daniel
- Simon Noah
- Singhvi Divya
- Sinha Deeksha
- Sinha Rajarishi
- Slayton Rachel B.
- Smith Claire P.
- Soni Saksham
- Soohoo Connor
- Spaeder Jeffrey
- Spantidakis Ioannis
- Spatz Ryan
- Srivastava Ajitesh
- Stage Steven A.
- Stark Ariane
- Stiefeling Chris
- Suchoski Bradley T.
- Sumner Timothy
- Sun Jimeng
- Sun Tao
- Sundar Saketh
- Swann Julie L.
- Tabassum Anika
- Tallaksen Katharine
- Tec Mauricio
- Thanou Dorina
- Thayaparan Leann
- Tibshirani Rob
- Tibshirani Ryan J.
- Tirumala Kushal
- Tiwari Avtansh
- Tomar Vishal
- Tran Quoc
- Truelove Shaun A.
- Trump Benjamin D.
- Tsai Thomas
- Tseng Albert
- Tsiourvas Asterios
- Turner Stephen D.
- Turtle James
- US COVID-19 Forecast Hub Consortium
- Vahedi Behzad
- Van Bussel Frank
- van de Walle Axel
- Varadarajan Vignesh
- Venkatramanan Srinivasan
- Ventura Valerie
- Vespignani Alessandro
- Vytheeswaran Jagath
- Walker Jo W.
- Walraven Robert
- Wang Christopher
- Wang Dongdong
- Wang Dongliang
- Wang Guannan
- Wang Lijing
- Wang Lily
- Wang Lingxiao
- Wang Liqiang
- Wang Qinxia
- Wang Yijin
- Wang Yu-Xiang
- Wang Yuanjia
- Wang Yueying
- Wang Zhongying
- Wasserman Larry
- Wattanchit Nutcha
- Weisberg Shane
- White Jerome
- Wilde Joshua
- Wilkinson Barrie
- Wills Josh
- Wilson Austin
- Wilson Daniel
- Wilson Shelby
- Wolffram Daniel
- Wolfinger Russ
- Wong Alexander
- Woody Spencer
- Wu Dongxia
- Xiao Cao
- Xiao Jade
- Xie Jiajia
- Xie Shanghong
- Xie Xing
- Xiong Xinyue
- Xu Pan
- Xu Tianjian
- Yamana Teresa K.
- Yan Xifeng
- Yeluri Akshay
- Yeung Dit-Yan
- Yoder Nate
- Yogurtcu Osman N.
- Yoon Jinsung
- You Jialu
- Yu Rose
- Yu Shan
- Yurk Dominic
- Zeng Donglin
- Zhang Leyou
- Zhang Michael
- Zhang Shun
- Zhang Shunpu
- Zhang Weitong
- Zhang-James Yanli
- Zhao Yanting
- Zheng Andrew
- Zheng Shun
- Zhou Mingyuan
- Zimmerman Peter
- Zlokapa Alexander
- Zoraghein Hamidreza
- Zorn Martha W.
- Zou Difan
- Zou Zihang
- Publication venue
- Nature Research
- Publication date
- 17/08/2022
- Field of study
Academic researchers, government agencies, industry groups, and individuals have produced forecasts at an unprecedented scale during the COVID-19 pandemic. To leverage these forecasts, the United States Centers for Disease Control and Prevention (CDC) partnered with an academic research lab at the University of Massachusetts Amherst to create the US COVID-19 Forecast Hub. Launched in April 2020, the Forecast Hub is a dataset with point and probabilistic forecasts of incident cases, incident hospitalizations, incident deaths, and cumulative deaths due to COVID-19 at county, state, and national, levels in the United States. Included forecasts represent a variety of modeling approaches, data sources, and assumptions regarding the spread of COVID-19. The goal of this dataset is to establish a standardized and comparable set of short-term forecasts from modeling teams. These data can be used to develop ensemble models, communicate forecasts to the public, create visualizations, compare models, and inform policies regarding COVID-19 mitigation. These open-source data are available via download from GitHub, through an online API, and through R packages
Genetic correlation between amyotrophic lateral sclerosis and schizophrenia
- Author
- Aarno Palotie
- Aaron R. Wolen
- Abraham Reichenberg
- Adriano Chio
- Aiden Corvin
- Alan Pittman
- Alan R. Sanders
- Albert C. Ludolph
- Albert Hofman
- Aleksey Shatunov
- Alessandro Padovani
- Alexander L. Richards
- Alexandra DĂŒrr
- Alexis Brice
- Alkes Price
- Ammar Al-Chalabi
- An Goris
- Anders D. BĂžrglum
- Andre Franke
- Andre G. Uitterlinden
- Andrea Calvo
- Andrea Hofman
- Andrea Malaspina
- Andres Metspalu
- Andrew J. Pocklington
- Andrew M. McIntosh
- Andrew McQuillin
- Andrey Khrunin
- Anil K. Malhotra
- Ann E. Pulver
- Ann Olincy
- Anna K. KĂ€hler
- Anneke J. van der Kooi
- Annelie Nordin
- Annelot M. Dekker
- Annette M. Hartmann
- Antonia Ratti
- Antonio JuliĂ
- Ariel Darvasi
- Ashley R. Jones
- Assen V. Jablensky
- Ayman H. Fanous
- Bela Melegh
- Benjamin M. Neale
- Bernard Lerer
- Bernhard Landwehrmeyer
- Bertram MĂŒller-Myhsok
- Bettina Konte
- Bradley N. Smith
- Bradley T. Webb
- Brandon K. Wormley
- Brendan Bulik-Sullivan
- Brien P. Riley
- Brion S. Maher
- Bryan J. Mowry
- C Robert Cloninger
- Carin J. Meijer
- Carlos N. Pato
- Carmel M. Loughland
- Carsten Drepper
- Catherine Lomen-Hoerth
- Cathryn M. Lewis
- Charles Curtis
- Chiara Zecca
- Chris C. A. Spencer
- Christian Hammer
- Christian Lunetta
- Christian R. Andres
- Christian R. Schubert
- Christina M. Hultman
- Christine A. M. Payan
- Christophe Tzourio
- Christopher E. Shaw
- Christos Pantelis
- Cindy Maurel
- Cinzia Bertolin
- Cinzia Gellera
- Cinzia Tiloca
- Claudine Laurent
- Clement C. Zai
- Colm McDonald
- Colm OâDushlaine
- Cristina Cereda
- Cristina Moglia
- Dai Wang
- Dan Rujescu
- Daniel G. Bradley
- Daniel R. Weinberger
- Danielle Posthuma
- David A. Collier
- David Cohen
- David Curtis
- David Kavanagh
- David M. Hougaard
- David St Clair
- Deborah A. Nertney
- Denis Bauer
- Derek W. Morris
- Dermot Walsh
- Diana O. Perkins
- Dick Schijven
- Dieter B. Wildenauer
- Digby Quested
- Dimitris Dikeos
- Ditte Demontis
- Dominic B. Rowe
- Dominique Campion
- Donald W. Black
- Douglas F. Levinson
- Douglas H. R. Blackwood
- Douglas M. Ruderfer
- Draga Toncheva
- Dragan M. Svrakic
- Eadbhard OâCallaghan
- Edward M. Scolnick
- Elena Parkhomenko
- Eli A. Stahl
- Elisabeth Stogmann
- Elisabetta Pupillo
- Elizabeth Bevilacqua
- Elodie Drapeau
- Elvira Bramon
- Emily H. M. Wong
- Engilbert Sigurdsson
- Enrico Domenici
- Eric F. C. Cheung
- Eric Strengman
- Eric Y. H. Chen
- Erik G. Jönsson
- Erik Söderman
- Esben Agerbo
- Ettore Beghi
- F Anthony OâNeill
- Farooq Amin
- Federico Casale
- Fernando Rivadeneira
- Filip Eftimov
- Frank Dudbridge
- Frank P. Diekstra
- Frans A. Henskens
- Franziska Degenhardt
- François Salachas
- Fritz Zimprich
- Garth A. Nicholson
- Gary Donohoe
- George Kirov
- George N. Papadimitriou
- Gerald Nestadt
- Gerome Breen
- Giacomo P. Comi
- Giancarlo Logroscino
- Gianni SorarĂč
- Gilbert Bensimon
- Giulio Genovese
- Guiqing Cai
- Hailiang Huang
- Hana Kuzelova-Ptackova
- Hannelore Ehrenreich
- Henrik B. Rasmussen
- Hon-Cheong So
- Hreinn Stefansson
- Hualin Simon Xi
- Hugh Gurling
- Ian Blair
- Igor Nenadic
- Ina Giegling
- Inez Myin-Germeys
- Inge Joa
- Ingrid Agartz
- Ingrid Melle
- Isabella Fogh
- Jaana Suvisaari
- Jacob Gratten
- Jacqueline I. Goldstein
- Jacques Mallet
- James A. Knowles
- James J. Crowley
- James L. Kennedy
- James T. R. Walters
- Jan H. Veldink
- Jan Lubinski
- Jana Strohmaier
- Janis Klovins
- Jean- François Dartigues
- Jeffrey Lieberman
- Jennifer L. Moran
- Jens R. Wendland
- Jeremy M. Silverman
- Jesus S. Mora
- Jianjun Liu
- Jianxin Shi
- Jim Van Os
- Jimmy Lee
- Jin P. Szatkiewicz
- Jo Knight
- Jochen H. Weishaupt
- Joel N. Hirschhorn
- Johan Eriksson
- John E. Landers
- John Hardy
- John Powell
- John Q. Trojanowski
- John Waddington
- Jonathan Glass
- Jonathan Pimm
- Jordan W. Smoller
- Josef Frank
- Joseph D. Buxbaum
- Joseph I. Friedman
- Joshua L. Roffman
- Jouko Lönnqvist
- Jubao Duan
- Judit Bene
- Juha Karjalainen
- Juha Veijola
- Jurgen Del Favero
- Jurjen J. Luykx
- Kai-How Farh
- Kang Sim
- Karen E. Morrison
- Kari Stefansson
- Karol Estrada
- Katie Sidle
- Kelly Williams
- Kenneth L. Davis
- Kenneth S. Kendler
- Kieran C. Murphy
- Kimberley D. Chambert
- Kristel R. van Eijk
- Kristin K. Nicodemus
- Kuang Lin
- Kung-Yee Liang
- Larry J. Seidman
- Laura Nisenbaum
- Lauren Elman
- Laurent Essioux
- Leo McCluskey
- Leonard H. van den Berg
- Letizia Mazzini
- Liene Nikitina-Zake
- Lieuwe de Haan
- Lili Milani
- Line Olsen
- Luba Kalaydjieva
- Lude Franke
- Lukas Tittmann
- Lyudmila Georgieva
- Madeline Alexander
- Mads V. Hollegaard
- Mamede de Carvalho
- Manuel Mattheisen
- Marcella Rietschel
- Margaret OâBrien
- Margot Albus
- Mari Nelis
- Marian L. Hamshere
- Marianne de Visser
- Marion Friedl
- Mark A. Reimers
- Mark Hansen
- Mark J. Daly
- Mark Weiser
- Markus M. Nöuthen
- Markus Weber
- Martilias S. Farrell
- Martin Begemann
- Martina Wiedau-Pazos
- Masashi Ikeda
- Massimiliano Filosto
- Matthew C. Keller
- Matthew C. Kiernan
- Maura Brunetti
- Menachem Fromer
- Meraida Polak
- Miaoxin Li
- Michael A. van Es
- Michael C. OâDonovan
- Michael Davidson
- Michael Gill
- Michael J. Owen
- Michael Sendtner
- Michele T. Pato
- Milan Macek
- Milena Blagojevic-Radivojkov
- Milica Pejovic-Milovancevic
- Morten Mattingsdal
- Mythily Subramaniam
- Nadine Cohen
- Nakao Iwata
- Nancy G. Buccola
- Naomi R. Wray
- Naser Durmishi
- Nazli Basak
- Nelson B. Freimer
- Nicholas Wood
- Nick Craddock
- Nicola Ticozzi
- Nigel M. Williams
- Nilo Riva
- Noa Carrera
- null null
- null null
- Ole A. Andreassen
- Ole Mors
- Olli PietilÀinen
- Orietta Pansarasa
- Orla Hardiman
- P Nigel Leigh
- Pablo V. Gejman
- Pak C. Sham
- Pamela J. Shaw
- Pamela Sklar
- Panos Roussos
- Paola Giusti-RodrĂguez
- Patricia T. Michie
- Patrick F. Sullivan
- Patrick Vourc'h
- Patrik K. E. Magnusson
- Paul Cormican
- Per Hoffmann
- Perry T. C. van Doormaal
- Peter A Holmans
- Peter Eichhammer
- Peter Lichtner
- Peter M. Andersen
- Peter M. Visscher
- Petr Slominsky
- Phil Lee
- Philip Van Damme
- Philippe Amouyel
- Philippe Corcia
- Pietro Fratta
- Preben B. Mortensen
- Qiang Wang
- Qingqin S. Li
- R Jeroen Pasterkamp
- Randy L. Buckner
- Raquelle I. Mesholam-Gately
- Raymond C. K. Chan
- René S. Kahn
- Ricardo Rojas-GarcĂa
- Richard A. Belliveau
- Richard Bruggeman
- Richard E. Straub
- Richard W. Orrell
- Rick A. A. van der Spek
- Rita M. Cantor
- Robert Freedman
- Robert H. Brown
- Robert Swingler
- Robert W. McCarley
- Roberto Del Bo
- Robin M. Murray
- Rodney J. Scott
- Roel A. Ophoff
- Roger Pamphlett
- Rolf Adolfsson
- Ronald Y. L. Chan
- Rosa Capozzo
- Rosanna Tortelli
- Russell L. McLaughlin
- S Hong Lee
- Safa Saker-Delye
- Sandra DâAlfonso
- Sandra Meier
- Sang-Yun Oh
- Sara L. Pulit
- Sara Marsal
- Sarah E. Bergen
- Sarah Tosato
- Sena Karachanak-Yankova
- Sergi Papiol
- Shaun M. Purcell
- Shuna Colville
- Sibylle G. Schwab
- Siddharthan Chandran
- Silvana Penco
- Silviu A. Bacanu
- Simon Arcuti
- Siow Ann Chong
- Sophie E. Legge
- Srdjan Djurovic
- Srihari Gopal
- Srinivas Thirumalai
- Stacy Steinberg
- Stanley V. Catts
- Stefan Herms
- Stephan Ripke
- Stephanie Godard
- Stephanie H. Witt
- Stephanie Williams
- Steven A. McCarroll
- Stéphanie Millecamps
- Susana Pinto
- Susanna Abdulla
- Susanne Petri
- Sven Cichon
- Svetlana Limborska
- T Scott Stroup
- Tao Li
- Teimuraz Silagadze
- Thomas G. Schulze
- Thomas Hansen
- Thomas Meitinger
- Thomas Meyer
- Thomas Werge
- Tiina Paunio
- Tim B. Bigdeli
- Tim Kahlke
- Timothy Dinan
- Todd Lencz
- Tracey L. Petryshen
- Tune H. Pers
- TÔnu Esko
- Ulrich Schall
- Vahram Haroutunian
- Vaidutis Kucinskas
- Valentina Escott-Price
- Vaughan J. Carr
- Veikko Salomaa
- Vera Golimbet
- Vihra Milanova
- Vincent Meininger
- Vincenzo Silani
- Viviana Pensato
- Vivianna M. Van Deerlin
- Wei Cheng
- Wiepke Cahn
- William Byerley
- William Sproviero
- Wim Robberecht
- Wolfgang Lieb
- Wolfgang Maier
- Wouter van Rheenen
- Xuebin Zheng
- Younes Mokrab
- Yunjung Kim
- Zita Ausrele Kucinskiene
- Publication venue
- Publication date
- 01/01/2017
- Field of study
A. Palotie on työryhmÀn Schizophrenia Working Grp Psychiat jÀsen.We have previously shown higher-than-expected rates of schizophrenia in relatives of patients with amyotrophic lateral sclerosis (ALS), suggesting an aetiological relationship between the diseases. Here, we investigate the genetic relationship between ALS and schizophrenia using genome-wide association study data from over 100,000 unique individuals. Using linkage disequilibrium score regression, we estimate the genetic correlation between ALS and schizophrenia to be 14.3% (7.05-21.6; P = 1 x 10(-4)) with schizophrenia polygenic risk scores explaining up to 0.12% of the variance in ALS (P = 8.4 x 10(-7)). A modest increase in comorbidity of ALS and schizophrenia is expected given these findings (odds ratio 1.08-1.26) but this would require very large studies to observe epidemiologically. We identify five potential novel ALS-associated loci using conditional false discovery rate analysis. It is likely that shared neurobiological mechanisms between these two disorders will engender novel hypotheses in future preclinical and clinical studies.Peer reviewe
Finishing the euchromatic sequence of the human genome
- Author
- . Haifeng
- . Magner
- . Yin
- Abbott Scott
- Abbott-Ozersky Amanda
- Abdellah Zahra
- Abouelleil Amr
- Abrajano Anne
- Adachi Tamami
- Adam Catherine
- Adams Charles Q.
- Adamson Aaron
- Adekoya Emmanuel
- Adio-Oduola Babajide
- Aerts Andrea
- Aggarwal Arun
- Ahmadi Alireza
- Ahmed Shahana
- Aimable Matthew
- Ainscough Rachael
- Ait-Zahra Mostafa
- Aizu Tomoyuki
- Alcivare Dana
- Alegria Michelle
- Ali Alla
- Ali Johar
- Allegria-hartmann Michelle
- Alleman Jennifer
- Allen Carlana C.
- Allen Heather
- Allen Nicole R.
- Allen Susan
- Allen Thaddeus
- Almeida Jeff
- Almond Claire
- Alsbrooks Stephen L.
- Altherr Michael R.
- Amaratunge Harshinie C.
- Ambler Andrew
- Ambrose Karen
- Ambrose Kerrie
- Amemiya Chris
- Amico-Keller Gina
- Amin Amita G.
- Anderson Mechele
- Anderson Scott
- Anderson Scott
- Andora Janice
- Andredesz Carol
- Andrew Robert
- Andrews Dan
- Andrews Daniel
- Andrews Neil
- Andrews Stephanie
- Andriese Tim
- Anthouard VĂ©ronique
- Antonarakis Stylianos E.
- Anyalebechi Vivian
- Aoki Norie
- Apostolou Sinoula
- Apweiler Eva
- Arachchi Harindra
- Arai Rie
- Arbery Hazel
- Arcaina Marlon
- Arcaina Terisita
- Archer Beth
- Arellano Andre
- Arellano-Jones Perry
- Armbruster Jeff
- Armstrong Jon
- Arredondo Dilrukshi P.
- Arredondo Heather Hope
- Artiguenave François
- Asakawa Shuichi
- Asakawa Teruyo
- Ash Gareth
- Ashcroft Kevin
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- Zhang Xiuqing
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- Zhang Yi
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- Zhang Yilin
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- Zhang Yuansen
- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers âŒ99% of the euchromatic genome and is accurate to an error rate of âŒ1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
The genetic architecture of the human cerebral cortex
- Author
- Adams Hieab H H
- Adams Hieab H H
- Agartz Ingrid
- Ahlijanian Michael
- Ahmad Shahzad
- Ainscough Susan
- Aisen Paul
- Albers Colleen S
- Albert Marilyn
- Alhusaini Saud
- Allard Joanne
- Almeida Marcio A A
- AlnĂŠs Dag
- Alvim Marina K M
- Ames David
- Ames David
- Amin Najaf
- Amlien Inge K
- Amouyel Philippe
- Ances Beau
- Anderson Karen
- Anderson Tim J
- Andersson Micael
- Andreassen Ole A
- Andreassen Ole A
- Apostolova Liana
- Ard Tyler
- Arias-Vasquez Alejandro
- Armstrong Nicola J
- Armstrong Nicola J
- Arnedo Vanessa
- Arnold Steven E
- Artiges Eric
- Artiges Eric
- Ashley-Koch Allison
- Assaly Michele
- Assareh Amelia A
- Asthana Sanjay
- Atkins Joshua R
- Aydin Semiha
- Ayesa-Arriola Rosa
- Baca Marne
- Bachman David
- Banaschewski Tobias
- Barbot Alexis
- Barker Gareth
- Barone Paolo
- Bartha Rob
- Bartzokis George
- Bastin Mark E
- Bastin Mark E
- Bates Vernice
- Baune Bernhard T
- Becerra Mauricio
- Becker Andreas
- Becker James T
- Beckett Laurel
- Beckham Jean C
- Beiser Alexa S
- Belden Christine M
- Belger Aysenil
- Bell Karen L
- Berg Daniela
- Bergman Howard
- Bernard Manon
- Bernard Manon
- Bernick Charles
- Bernstein Matthew
- Beyer Frauke
- Bezivin-Frere Pauline
- Biondo Francesca
- Bis Joshua C
- Bis Joshua C
- Bishop Courtney
- Black Sandra
- Blangero John
- Blank Karen
- Bodge Courtney
- Bokde Arun
- Bonakdarpour Borna
- Boomsma Dorret I
- Borges-Neto Salvador
- Borowski Bret
- Borrie Michael
- Bralten Janita
- Brand Connie
- Brandabur Melanie
- Brandt Christine L
- Brewer James
- Brockington John
- Brodaty Henry
- Brodaty Henry
- Bromberg Uli
- Brooks David
- Brooks William M
- Brosch Jared R
- Brouwer Rachel M
- Brown Gregory G
- Bruehl Ruediger
- Brunner Han G
- Buckholtz Neil
- Buckner Randy L
- Budson Andrew E
- Buimer Elizabeth E L
- Buitelaar Jan K
- Burke Anna
- Burns Jeffrey M
- Bustillo Juan R
- BĂŒlow Robin
- BĂŒlow Robin
- BĂŒrger Christian
- BĂżchel Christian
- Cabrera Yuliana
- Cahn Wiepke
- Cairns Murray J
- Cairns Nigel J
- Calhoun Vince
- Cannon Dara M
- Capote Horacio
- Carlsson Cynthia M
- Carmichael Owen
- Carr Vaughan J
- Carrillo Maria
- Carroll Maria
- Carson Richard E
- Carter Raina
- Casaceli Cynthia
- Casalin Paola
- Caseras Xavier
- Caspell Chelsea
- Caspers Svenja
- Catafau Ana
- Cavalleri Gianpiero L
- Cedarbaum Jesse
- Cellar Janet S
- Celmins Dzintra
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- Chakravarty Mallar
- Chalker Alison
- Chao Steven
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- Chertkow Howard
- Cheung Joshua W
- Chiang Gloria
- Ching Christopher R K
- Chowdhury Munir
- Chowdhury Sohini
- Chu Congying
- Cichon Sven
- Clark Christopher M
- Clark David
- Coffey Christopher
- Coleman Edward
- Colodro-Conde LucĂa
- Comery Thomas
- Conrad Gary
- Conrod Patricia
- Consortium CHARGE
- Consortium Enhancing NeuroImaging Genetics through Meta-Analysis
- Consortium EPIGEN
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- Correia Stephen
- Corvin Aiden
- Couvy-Duchesne Baptiste
- Crawford Karen
- Creech Mary L
- Crespo-Facorro Benedicto
- Crivello Fabrice
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- D'Agostino Daniel
- Daedelow Laura
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- Dale Anders M
- Dalley Jeffrey
- Dalrymple-Alford John C
- Dalvie Shareefa
- Dang Mimi
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- Darin Abigail
- Davies Gareth E
- Davies Peter
- de Araujo TĂąnia K
- de Geus Eco J C
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- Goldstein David B
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- HĂ€usler Alexander N
- HĂ„berg Asta K
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- Ikeda Masashi
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- Ittermann Bernd
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- Wardlaw Joanna M
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- Weinberger Daniel R
- Weiner Michael
- Weiner Michael W
- Weintraub Sandra
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- Wen Wei
- Westlye Lars T
- Whelan Christopher D
- Whelan Robert
- Whelan Robert
- White Tonya
- Willeke Diana
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- Wilson Renee
- Winkfield David
- Witbracht Megan
- Witt Stephanie H
- Witte A Veronica
- Wittfeld Katharina
- Wittfeld Katharina
- Wolf Christiane
- Wolfers Thomas
- Wolk David A
- Womack Kyle
- Wong Terence Z
- Woo Ellen
- Wright Margaret J
- Wright Margaret J
- Wu Chuang-Kuo
- Wu Jing Qin
- Wurster Isabel
- Xia Rui
- Yamamori Hidenaga
- Yanez Beatriz
- Yang Mia
- Yang Qiong
- Yang Qiong
- Yankey Jon
- Yasuda Clarissa L
- Yeh Randy
- Yesavage Jerome
- Zamrini Edward
- Zare Habil
- Zaremba Dario
- Zhang Zuo
- Zhou Juan
- Zhu Alyssa H
- Zimmerman Earl A
- Ziolkowski Jaimie
- Zsembik Leo C P
- Zwiers Marcel P
- Publication venue
- 'American Association for the Advancement of Science (AAAS)'
- Publication date
- 01/01/2020
- Field of study
The cerebral cortex underlies our complex cognitive capabilities, yet little is known about the specific genetic loci that influence human cortical structure. To identify genetic variants that affect cortical structure, we conducted a genome-wide association meta-analysis of brain magnetic resonance imaging data from 51,665 individuals. We analyzed the surface area and average thickness of the whole cortex and 34 regions with known functional specializations. We identified 199 significant loci and found significant enrichment for loci influencing total surface area within regulatory elements that are active during prenatal cortical development, supporting the radial unit hypothesis. Loci that affect regional surface area cluster near genes in Wnt signaling pathways, which influence progenitor expansion and areal identity. Variation in cortical structure is genetically correlated with cognitive function, Parkinson's disease, insomnia, depression, neuroticism, and attention deficit hyperactivity disorder
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
- Author
- Abdel-Aziz AK
- Abdelfatah S
- Abdellatif M
- Abdoli A
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- Abeliovich H
- Abildgaard MH
- Abudu YP
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- Ziviani E
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- Zorzano A
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- Ălvarez ĂMC
- Ăvalos Y
- Ănal G
- ĂstĂŒn S
- ÄoliÄ M
- ÄokiÄ J
- Ćœerovnik E
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2021
- Field of study
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field
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