67 research outputs found
Common Dermatoses in Patients with Obsessive Compulsive Disorders
- Publication venue
- ValpoScholar
- Publication date
- 05/11/2015
- Field of study
Obsessive-compulsive disorder is a chronic, debilitating syndrome, consisting of intrusive thoughts- which are experienced as inappropriate by the patient and are producing anxiety- and compulsions, defined as repetitive behaviours produced to reduce anxiety. While patients with obsessive-compulsive disorder typically have xerosis, eczema or lichen simplex chronicus, as a result of frequent washing or rubbing their skin, several other disorders which are included in the group of factitious disorders have also been associated with obsessive-compulsive disorder. A close collaboration between the dermatologist and the psychiatrist is therefore mandatory in order to achieve favourable outcomes for these patients. The aim of the article is to present the most frequent dermatological disorders associated with obsessive-compulsive disorder and to look over some of the rare ones
PU.1 controls fibroblast polarization and tissue fibrosis
- Author
- Beyer Christian
- Boykin David W.
- Butter Falk
- Chen Chih-Wei
- Daniel Christoph
- Dees Clara
- Distler Jörg H. W.
- Distler Oliver
- Ekici Arif
- Finotto Susetta
- Gay Steffen
- Gelse Kolja
- Jüngel Astrid
- Kaplan Mark H.
- Karouzakis Emmanuel
- Kiener Hans P.
- Kremer Andreas E.
- Kreuter Alexander
- Luber Markus
- Maier Christiane
- Matei Alexandru-Emil
- Naschberger Elisabeth
- Nutt Stephen L.
- Pachera Elena
- Poon Gregory M. K.
- Ramming Andreas
- Rauber Simon
- Schett Georg
- Soare Alina
- Sticherling Michael
- Stürzl Michael
- Uebe Steffen
- Weber Stefanie
- Wohlfahrt Thomas
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/02/2019
- Field of study
Fibroblasts are polymorphic cells with pleiotropic roles in organ morphogenesis, tissue homeostasis and immune responses. In fibrotic diseases, fibroblasts synthesize abundant amounts of extracellular matrix, which induces scarring and organ failure. By contrast, a hallmark feature of fibroblasts in arthritis is degradation of the extracellular matrix because of the release of metalloproteinases and degrading enzymes, and subsequent tissue destruction. The mechanisms that drive these functionally opposing pro-fibrotic and pro-inflammatory phenotypes of fibroblasts remain unknown. Here we identify the transcription factor PU.1 as an essential regulator of the pro-fibrotic gene expression program. The interplay between transcriptional and post-transcriptional mechanisms that normally control the expression of PU.1 expression is perturbed in various fibrotic diseases, resulting in the upregulation of PU.1, induction of fibrosis-associated gene sets and a phenotypic switch in extracellular matrix-producing pro-fibrotic fibroblasts. By contrast, pharmacological and genetic inactivation of PU.1 disrupts the fibrotic network and enables reprogramming of fibrotic fibroblasts into resting fibroblasts, leading to regression of fibrosis in several organs
Engrailed 1 coordinates cytoskeletal reorganization to induce myofibroblast differentiation
- Author
- Publication venue
- 'Rockefeller University Press'
- Publication date
- 06/09/2021
- Field of study
Transforming growth factor-β (TGFβ) is a key mediator of fibroblast activation in fibrotic diseases, including systemic sclerosis. Here we show that Engrailed 1 (EN1) is reexpressed in multiple fibroblast subpopulations in the skin of SSc patients. We characterize EN1 as a molecular amplifier of TGFβ signaling in myofibroblast differentiation: TGFβ induces EN1 expression in a SMAD3-dependent manner, and in turn, EN1 mediates the profibrotic effects of TGFβ. RNA sequencing demonstrates that EN1 induces a profibrotic gene expression profile functionally related to cytoskeleton organization and ROCK activation. EN1 regulates gene expression by modulating the activity of SP1 and other SP transcription factors, as confirmed by ChIP-seq experiments for EN1 and SP1. Functional experiments confirm the coordinating role of EN1 on ROCK activity and the reorganization of cytoskeleton during myofibroblast differentiation, in both standard fibroblast culture systems and in vitro skin models. Consistently, mice with fibroblast-specific knockout of En1 demonstrate impaired fibroblast-to-myofibroblast transition and are partially protected from experimental skin fibrosis
Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis
- Author
- Aahlin Eirik Kjus
- Aamer Ahmed
- Aaniana Kenneth
- Ababneh Ali
- Abaliksta Tomas
- Abantanga Francis
- Abbas Athar
- Abbasy Jibran
- Abbo Olivier
- Abbott Tom
- Abbouch Meryem
- Abd El-Latif Nadia Khalid
- Abd Elkhalek Esraa
- Abd-Elmawla Manar
- Abdallah Emad
- Abdel-Aty Abdulrahman
- Abdel-Hameed Noran
- Abdel-Kader Sara Mahmoud
- Abdelaal Abdelaziz
- Abdelaty Mohamed
- Abdelazeam Anan Rady
- Abdelazim Galaleldin
- Abdelaziz Mohamed A.
- Abdelbadeai Kholoud
- Abdelfatah Afnan
- Abdelhady Samar
- Abdelhamed Rasha
- Abdelhamid Amina
- Abdelhaq Aram
- Abdelkader Mostafa
- Abdelkader Omar
- Abdelkhalek Mohamed
- Abdelmageed Eman
- Abdelmotaleb Ibrahem
- Abdelraouf Ahmed Mahmoud
- Abdelrouf Doaa Maher
- Abdelshakour Mahmoud
- Abdrabou Abdulshafi Khaled
- Abdul-Latif Saiba
- Abdulaziz Hager
- Abdulaziz Mustafa
- Abdulbagi Omar
- Abdulhakeem Eman Mahmoud
- Abdullah Mohamed Abozed
- Abdullah Nik Azim Nik
- Abdullah Noha
- Abdullahi Lawal
- Abdurrazzaaq Abdussemiu
- Abem Owusu Emmanuel
- Abiola Olajide
- Aboelella Majed
- Aboelmagd Omnia
- Aboelsoud Moustafa R.
- Aboul-Naga Mariam Saad
- Abouzaid Arwa
- Abu Qumbos Amjad
- Abu-toyour Maram
- Abubakr Marwan
- Abuowda Yousef
- Abuqwaider Eman
- Abusalem Lana
- Abushamleh Soha
- Ackom Eric
- Acquah Emmanuel
- Adam Ali
- Adam Nourhan
- Adamu Ahmed
- Adawi Ihdaa
- Adawi Mohammad
- Adebanjo Ademola
- Adebola Oluwaseyi
- Adedeji Adesina
- Adel Badr Eldin
- Adel Israa
- Adella Fidelis Jacklyn
- Adelshone Abdelrahman
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O.
- Ademuyiwa Adesoji O.
- Adenekan Babajide
- Adeniran James
- Adeniyi Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adeyeye Ademola
- Adeyeye Ademola
- Adhitama Novia
- Adil Muhammad
- Adisa Adewale O.
- Adiyaman Can
- Adu-Aryee Niiarmah
- Afana Samah
- Agalianos Christos
- Agarwal Arnav
- Agarwal Arnav
- Agbedinu Kwabena
- Aglan Amro
- Aguado Suarez Nuria
- Aguilera Maria Lorena
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlonsou Germain
- Ahlqvist Sandra
- Ahlqvist Sandra
- Ahmed Asdaq
- Ahmed Ataa
- Ahmed Hayam
- Ahmed Hussien
- Ahmed Lopna Ahmed Mohamed
- Ahmed Sara
- Ahmed Saraibrahim
- Ahounou Ernest Yemalin Stephane
- Ajah Jonathan
- Ajai Olalekan
- Ajao Akinlabi
- Ajiboye Anthony
- Akoto Elliot
- Akpenyi Onyinye
- Al Amin Shadid
- Al Attar Samaa Mahmoud
- Al Barraw Fayez Elian
- Al Bastawis Fatema
- Al Meligy Amgad
- Al Rafati Ahmad Abdel Razaq
- Al Raouf Eman Abd
- Al Saied Ghiath
- Al Subaie Norah
- Al-Bahrani Ahmed
- Al-Buhaisi Alaa
- Al-Dakka Emad
- Al-faqawi Maha
- Al-farram Hadeel
- Al-khatib Ahmed
- Al-Marakby Dina
- Al-saqqa Sara
- Al-Saqqa Sara W.
- Al-Slaibi Ibrahim
- Al-taher Taher
- AlaaelDein Shahinaz
- Alada Muslimat
- Alakaloko Felix
- Alaloul Enas
- Alamin Shadid
- Alamoudi Mohammed
- Albiety Adel
- Alcca Ticona Willy
- Alejos Bermudez Ysabel Esthefany
- Alexander Philip
- Alexander Philip
- Alexandre Challine
- Alghamdi Ahmed
- Alghamdi Mohammed Saleh A.
- Alhady Khaled
- Alhammali Tariq
- Alhassan Basmah
- Alhazmi Wedyan
- Alherz Mohammad
- Ali Ahmed
- Ali Citra Dewi Mohd
- Ali Elsayed
- Ali Safia
- Ali Syed Abdul Wahhab Eusoffee Wan
- Ali Tebian Hassanein Ahmed
- Ali Wadah
- Alihonou Thierry
- Alis Halil
- Aliyu Halima
- Aliyu Mohammad
- Aliyu Shamsudeen
- Aljboor Khaled
- Aljiffry Murad
- Alkaaki Aroub
- Alkelani Muhammad
- Allam Meran
- Allam Yomna
- Alnaby Mohamed Hassab
- Alnusairat Aseel
- Alqahtani Saleh
- Alsaggaf Mohammed Ubaid
- Alser Osaid H.
- Alshareef Reham
- Altaf Abdulmalik
- Altamimi Abdullah
- Altamimi Afnan
- Altamini Afnan
- Altarayra Marwa
- Altibi Ahmed
- Altinel Yuksel
- Altinel Yuksel
- Altwijri Abdulaziz
- Alvi Abdul Rehman
- Aly Mohammed Yahia Mohamed
- Alyacoubi Said
- Alyahya Reem
- Alzahrani Ahmed
- Aman Nowrin F.
- Amandito Radhian
- Amandito Radhian
- Ambrona-Zafra David
- Amin Hager Abdul Aziz
- Amjad Mohammadasim
- Amoah Michael
- Amoako Joachim
- Amoako Philip Taah
- Amoako-Boateng Mabel
- Amole Isaac
- Amreia Mahmoud
- Anderson Frank
- Andika Ferry Fitriya Ayu
- Andreotti Dario
- Andress Cedar
- Andriola Valeria
- Ang Yun Lin
- Angelieri Daniele
- Anis Echaieb
- Ansaloni Luca
- Ansaloni Luca
- Ansaloni Luca
- Antezana Diego
- Anthoulakis Christos
- Antoniozzi Angelo
- Anwar Nourhan
- Anyanwu Lofty-John
- Aonzo Paolo
- Appeadu-Mensah William
- Appiah Eric Kofi
- Aquilino Fabrizio
- Arafa Omar
- Arafa Sara
- Arango Maria Clara Mendoza
- Arcudi Claudio
- Armellini Andrea
- Arnaud Alexis
- Arnaud Alexis Pierre
- Arshad Mohammad Mohsin
- Arslan Ekin
- Arsyad Hasbi Maulana
- Arthur Tom
- Aruldas Neerav
- Asar Yomna Hosny
- Asare-Bediako Kwasi
- Ashour Ahmad
- Ashour Ahmad
- Ashour Khlood
- Ashtari Morvarid
- Asi Fatema
- Asilah Siti Mohd Desa
- Assal Abdelrahman
- Asturias Sabrina
- Asumah Hamza
- Ata Ahmed
- Ata Aya Yehia
- Atiyeh Anwar
- Atkins Ebenezer Takyi
- Attia Attia
- Augestad Knut Magne
- Aviles Susan
- Avoka Anthony
- Awad Israa
- Awad Sawsan Adel
- Awadallah Salwa
- Ayandipo Omobolaji
- Aydin Mehmet Can
- Aziz Dayang Nita Abdul
- Aziz Mohamed Rezal Abdul
- Aziz Nora Abdul
- Azizeldine Mohammed G.
- Azzie Georges
- Azzis Olivier
- Baba Suleiman
- Bachri Houda
- Badawy Mahmoud
- Badenjki Mohamed Adel
- Badicel Maria
- Badr Mohamed Fawzy Mahrous
- Badwi Nermin Mohamed
- Bahar Suraya
- Baillie Katie
- Baki Bahadir Emre
- Bakr Ahmad
- Bakry Hesham Mohammed
- Bala Miklosh
- Balalis Dimitrios
- Balducci Genoveffa
- Ballouhey Quentin
- Balmaceda Ruben
- Balmaceda Ruben
- Balogun Fatai
- Baltrunas Robertas
- Baluch Fatima
- Bamford Rebecca
- Bamicha Athanasia
- Banaitis Vincas Jonas
- Bandi Ashwath
- Bandoh Dickson
- Bani-Sadar Ahmad
- Banipal Gurpreet Singh
- Baquero Suarez Alibeth Andres
- Baraka Heba
- Barendegere Venerand
- Barkolias Christos
- Barmayehvar Behrad
- Barnabas Gandau Naa
- Barrios Emmanuel
- Basilico Silvia
- Basir Elissa Rifhan Mohd
- Bassem Monica
- Bassit Khalil Abdul
- Basso Stefano M. M.
- Bayram Sefa
- Beamon Mieshia
- Bedada Alemayehu Ginbo
- BediakoBowan Antoinette
- Bekhet Amira Hassan
- Bekhet Nada Mohamed
- Beleno Alvaro Enrique Mendoza
- Belkouchi Abdelkader
- Belli Andrea
- Bello Bashir
- Benammi Sarah
- Benevento Angelo
- Bennai Redouane Mammar
- Bentounsi Zineb
- Benyaiche Chaymae
- Berti Stefano
- Bertuello Isaac
- Beuran Mircea
- Bhangu Aneel
- Bhangu Aneel
- Bhangu Anna
- Bhatnagar Ankur
- Bhopal Kamran Faisal
- Bianco Federica
- Bigaran Annamaria
- Billy Matthew
- Bin Adnan Ahmad
- Bin Hasnan Muhammad
- Bin Ismail Mohamad Jeffrey
- Birindelli Arianna
- Bisset Carly
- Bjorklund Ida
- Blacker Sarah
- Blackwell James
- Blanco Ruth
- Blanco-Colino Ruth
- Blencowe Natalie
- Bliksoen Marte
- Bluelle Rafael
- Bocchetti Tommaso
- Bode Chris
- Bodur Selim
- Boggon Adam
- Bonavia Karl
- Bonavina Luigi
- Bond-Smith Giles
- Bondin John
- Bondurri Andrea
- Boni Silvia
- Bonney William
- Borda-Luque Giuliano
- Borg Elaine
- Borg Elaine
- Bortolasi Luca
- Bottini Corrado
- Bougard Heather
- Boukhal Khaoula
- Bowabsak Alaa
- Bowling Kirk
- Bradulskis Saulius
- Bratu Matei
- Bratu Matei Razvan
- Breaud Jean
- Breistrand Michaela
- Breslin Ryan
- Brincat Svetlana Doris
- Broch Aline
- Brunoni Beatrice
- Bsisu Isam
- Bucci Luigi
- Buisson Philippe
- Bunting David
- Burger Sule
- Burmistrovas Andrius
- Bustangi Nasir
- Bustangi Nasir
- Butt Muhammad Talha
- Cakaloglu Haluk Cem
- Caliman Celeste
- Callan Rory
- Camilleri Georgette Marie
- Camilleri-Brennan Julian
- Campagnaro Tommaso
- Canta Calua Alexander
- Capito Carmen
- Carabott Kurt
- Carmela Lapitan Marie
- Carmona Juan Manuel
- Carpio Juan
- Carrasco Nahilia
- Cassar Kristina
- Catani Marco
- Cautiero Roberto
- Caydiid Hanaan
- Cecilia Tolg
- Celik Saban
- Cengiz Turgut Bora
- Cengiz Yucel
- Cengiz Yucel
- Cevik Muazzez
- Chabok Abbas
- Chai Chu-Ann
- Chai Feng Yih
- Chan Luke
- Chan Tsz-Yan Katie
- Chan Xue Wei
- Charles Angeline
- Cheah Alvin Ee Zhiun
- Chen Kar Yan
- Chen Tzu-Ling
- Cheong Yih Jeng
- Chetta Nicola
- Cheung Yuk Hong Eric
- Chibuye Chali
- Chiesa Deborah
- Chilton Gareth
- Chin Pui Xin
- Chin Ye Ru
- Chiu Seehui
- Choi Philip
- Chong Choon Seng
- Chong Hoong-Yin
- Choudhry Asad
- Chow Crystal Yern Nee
- Chowdhury Debkumar
- Chu Kathryn
- Chung Kuet Jun
- Chungui Bravo Jorge Armando
- Ciccioli Eleonora
- Ciubotaru Cezar
- Claire Raquillet
- Clarissa Audrey
- Clegg-Lampety Joe-Nat
- Clegg-Lamptey Joe-Nat
- Clerico Giuseppe
- Coccolini Federico
- Coccolini Federico
- Cocorullo Gianfranco
- Cohen Fraser
- Cole Simon
- Coletta Diego
- Coletti Massimo
- Collaborative GlobalSurg
- Cona Camilla
- Conci Simone
- Confalonieri Gianmaria
- Conlon Kevin C.
- Connor Katie
- Contreras Elisa
- Coompson Christian Lari
- Corbellini Carlo
- Corbellino Mario
- Cornick Jen
- Coronel Jazmin
- Corral Moreno Sara
- Correa Juan Camilo
- Corro-Diaz Samantha
- Costa Cecilia
- Costa-Maia Jose
- Costas-Chavarri Ainhoa
- Courboin Etienne
- Cox Daniel
- Cox Michael
- Coyoy-Gaitan Otto
- Craus-Miguel Andrea
- Cullen Fraser
- Curletti Gianluca
- Currow Chelise
- D'Amours Scott
- D'Souza Michelle S.
- Dabboor Majd
- Dabbour Kareem
- Dagoe Enoch
- Dahy Ahmed
- Dainius Edvinas
- Dakubo Jonathan
- Dalli Jeffrey
- Dally Charles
- Dambrauskas Zilvinas
- Daniyan Muhammad
- Danys Donatas
- Dao Weihei
- Dar Wasim
- Dardenne Sabrina
- Darwish Abdelrhman K. Z.
- Dasari Mohini
- Dashnyam Enkhbat
- Dassah Victor
- Datta Uttaran
- Davies Rachel
- Davor Anthony
- Dawood Khaled
- Dayie Makafui
- De Boni Davide
- De Franciscis Silvia
- De Luca Emilia
- De Marco Paolino
- Deal Rebecca
- Deane Chelsea
- Debrah Sam
- Dedekind Britta
- Dedey Florence
- Del Basso Celeste
- del Pilar Paucar Arazzelly
- Delforge Xavier
- Dell Angela
- Denakpo Max
- Denewar Adel
- Depalma Norma
- Der Yishan
- Deutschmann Peter
- Dhillon Dharminder
- Di Martino Natale
- Di Saverio Salomone
- Diaconescu Bogdan
- Diaz Vico Tamara
- Diaz Zorrilla Carmina
- Diaz-Jover Paula
- Dick Lachlan
- Dijan Emilio
- Dimech Thea
- Din Farhat
- Dindyal Shiva
- Dione Parreno-Sacdalan Marie
- Dissanayake Tharindra
- Djivoh Fernande
- Domini Edgar
- Donnelly Philippa
- Dorani Radin Mohd Nurrahman Radin
- Dorisme Asnel
- Dossou Francis
- Dousset Bertrand
- Dragatas Deividas
- Drake Thomas M.
- Drake Thomas M.
- Drungilas Mantas
- du Plooy Flip
- Du Toit Frederick
- Duane Therese
- Duinhouwer Lucia
- Dulskas Audrius
- Ebidy Mai
- Ebidy Mai Mohamed
- Eid Mostafa Mahmoud
- El Dahab Ali Abo
- El Gendy Noran Halim
- El Halawany Mohamed
- El Jamassi Alaa
- El Kashash Ahmed
- El Sayed Islam Magdy
- El-Dien Khalid Salah
- El-Din Reham Alaa
- El-Din Shahinaz Alaa
- El-Gizawy Esraa
- El-Sagheer Nada
- El-Sawy Aya
- El-Sehily Ahmed
- El-Taher Esraa
- Elashry Rehab
- Elazab Alaa
- Elbanby Esraa Samir
- Elbe Peter
- Elbisomy Khaled Hesham
- Eldafrawy Mahmoud
- Eldeeb Ahmed Zaki
- Eldeen Esraa Alm
- Eldin Mostafa Ahmed Bahaa
- Elebute Olumide
- Elfarargy Arwa
- Elfeki Hossam
- Elfiky Mahmoud
- Elfouly Nesma
- Elfouly Yasmin
- Elgendy Alyaa Halim
- Elgheriany Mohammed
- Elhadad Alaa
- Elhadary Nourhan Medhat
- Elhadry Shady
- Elhalawany Esraa
- Elhamouly Sara
- Elhelbawy Mohamed Salah
- Elhendawy Abdelaziz
- Elhoseny Ghada
- Elhusseiny Ahmed Abd Elmoen
- Elkholy Shimaa Said
- Ellison Quinn
- Elmashala Amjad
- Elmasry Maha
- Elmihy Sohaila
- Elnagar Ahmedglal
- Elnajjar Mahmoud A.
- Elrazek Aly Abd
- Elsabbagh Nourhan
- Elsameea Ahmed Abd
- Elsawy Amira
- Elsayed Nada Ahmed Reda
- Elsemelawy Rofida
- Elshaar Mohammed
- Elshaer Mohamed
- Elshami Mohamedraed
- Elsharkawy Aya Adel
- Elsherbiney Saged
- Elsherif Fawzia Abdellatif
- Elwy Eman
- Elzahed Nada
- Emadeldin Hossam
- Emara Eman
- Emile Sameh
- Eng Calvin
- English William
- Esam Abeer
- Escalante Salas Marilia Del Carmen
- Espin-Basany Eloy
- Espinoza Fernando
- Essam A. A.
- Essam Ahmed
- Essam Mahitab
- Essoun Samuel
- Esteban Enrique
- Estee Mahnuma Mahfuz
- Etchill Eric
- Etienne Sara
- Etwire Victor
- Evajelista Cicilia Viany
- Evans David
- Evans Elizabeth
- Ezzat Eslam
- Ezzat Tarek
- Faboya Omolara
- Fahim Marwan
- Fairfield Cameron
- Falaschi Federica
- Falco Nicolo
- Falzon Malcolm
- Farag Ahmed
- Farag Sameh
- Farahat Mahitab Morsy
- Fares Mohamed
- Farhan-Alanie Muhamed M. H.
- Farhangmehr Neda
- Farouk Sara Amr Mohamed
- Farrugia Alexia
- Farrugia Alexia
- Faruq Amreen
- Fathy Aya Mohamed
- Fatuga Adedeji
- Faturoti Olubukola
- Favero Alessandro
- Feidantsis Thomas
- Fergany Alaa
- Fergusson Stuart J.
- Fergusson Stuart J.
- Fermani Claudio Gabriel
- Fernandes Cristina
- Fernandez Carmen
- Fernandez-Vega Laura
- Ferousis Christoforos
- Ferrero Esther
- Filatau Aliaksandr
- Firdouse Mohammed
- Firdouse Mohammed
- Firwana Aya
- Fitsum Agazi
- Fitzgerald J. Edward
- Fitzgerald J. Edward
- Florez Farfan Erick Samuel
- Foco Maurizio
- Fok Chi Ying Jacquelyn
- Fontana Tommaso
- Foo Chi Chung
- Forlin Louise
- Fouad Dina
- Fourcade Laurent
- Francisco Roxas Manuel
- Franco Helena
- Francois Poddevin
- Francone Elisa
- Frey Daniel
- Fuentes-Rivera Lorena
- Gaafar Shireen
- Gaarder Tina
- Gad Ahmed
- Gad Mariam O.
- Gadelkarim Mohamed
- Gado Ammar
- Gaizauskas Vytautas
- Gala Tanzeela
- Gala Tanzeela
- Galiqi Gezim
- Galleano Raffaele
- Gallo Gaetano
- Gamal Dina
- Gamal Esraa
- Gamal Heba
- Gamal Shimaa
- Gamil Doaa
- Gan Cheewei
- Gan Yiing Yee
- Gani Mohammed Akil
- Garcia Bernardo Carmen
- Garcia Septiem Javier
- Garcia-Florez Luis
- Gash Katherine
- Gash Katherine
- Gastaldi Pauline
- Gaujoux Sebastien
- Gavagna Laura
- Gbessi Dansou Gaspard
- Gemenetzis Georgios
- Germanos Stylianos
- Gerosa Alexandra
- Geuoshy Abdelrahman
- Ghaben Ahed
- Ghanem Ahmed
- Ghanem Sara
- Ghannam Mohammad
- Ghoneim Omar
- Giardino Francesco Ruben
- Giavarini Luisa
- Giglio Mariano Cesare
- Giraldo Ruben Santiago Restrepo
- Giuliani Stefano
- Gkiokas Georgios
- Glasbey James
- Glasbey James
- Glover-Addy Hope
- Glynn Martha
- Goh Wennweoi
- Goldin Elena
- Gonzales Montejo Maria Soledad
- Gonzalez Mariana
- Gonzalez Mariana
- Gouws Juan
- Gran Mads
- Gravante Gianpiero
- Gray Demi
- Grech Nicole
- Grella Maria Giovanna
- Gribauskaite Jolanta
- Griffiths Ewen
- Grima Tara
- Grisin Edvard
- Grizhja Besmir
- Grobler D. C.
- Grosos Celine
- Gubeli Alissa
- Gudal Ahmad
- Gudal Ahmad
- Guevara Torres Shalon
- Guglielmo Vania
- Gui Daniele
- Gul Enisburak
- Gulbinas Antanas
- Gulcicek Osman Bilgin
- Gulielmi Alfredo
- Gultom Phebe Anggita
- Gunaseelan Kuhaendran
- Gunawan Rudy
- Guner Ali
- Gupta Ashish
- Guzman Duenas Carolina
- Gyamfi Frank Enoch
- Gyedu Adam
- Habeeb Olufemi
- Haddad Nadeem
- Hafez Mohamed
- Hafez Sarah
- Haffreingue Aurore
- Hagan Richmond
- Haines Morgan
- Hajeh Haidar
- Halhouli Oday
- Halhouli Oday
- Halicioglu Ilkay
- Hall Elisabeth
- Haloho Andreass
- Hamarshi Aseel
- Hamasaki Hamaguchi Jose Luis
- Hamdan Ayah
- Hamdan Marwa
- Hamed Mohamed Fouad
- Hamill Daniel
- Hammad Aya
- Hampton Mark Ian
- Hamsho Ward
- Hanoun Sakhaa
- Hantour Usama
- Hany Ethar
- Haque Muhtarima
- Har Prisca A. L.
- Haraux Elodie
- Harrison Ewen M.
- Harrison Ewen M.
- Harrison Ewen M.
- Hartford Leila
- Harvey Neil
- Hasan Ahmad
- Hasan Doaa
- Hasanah Afifatun
- Hasanain Doaa
- Hascoet Juliette
- Hashad Eman
- Hashim Abdullah
- Haslegrave Aidan
- Hassaan Amr
- Hassaan Ayat
- Hassan Ahmed Tarek Abdelbaset
- Hassan Ihab
- Hassan Osama Mokhtar Mohamed
- Hassanain Mazen
- Hassanein Adel B.
- Heard Rachel
- Hegazy Eman Magdy
- Helene Francois-Coridon
- Helguero-Santin Luis M.
- Hemmila Mark
- Heng Hian Ee
- Henric Nicolas
- Henry Fitjerald
- Henshall David Ewart
- Herebat Azher
- Herikstad Ragnar
- Herrera Cruz Danilo
- Herrera Matta Juan Jaime
- Herrod Philip
- Hervieux Erik
- Hesham Omar
- Hilal Karim
- Hjertberg Maria
- Hmila Sophian
- Ho Adrienne
- Hodonou Fred
- Holte Silje
- Homeida Anmar
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- Vicario Erika
- Vicenta Collado Maria
- Vida Lucian Corneliu
- Vilcinskas Mantas
- Villalobos Santiago
- Violi Paola
- Visinskas Petras
- Voulgaris Evangelos
- Wael Noha
- Wakefield Rebecca
- Waledziak Maciej
- Walker Michael
- Walker Nathan
- Walls Luke
- Walsh Michael
- Waqar Muhammad
- Warren Oliver
- Waterman Ade
- Werder Gabriela
- Whitaker John
- White Rebecca
- Whitehurst Katharine
- Wiborg Joachim
- Widiastini T. Ariani
- Widmer Lukas Werner
- Wijayarathna L. S.
- Williams Omolara
- Wilson Ling
- Wilson Michael
- Wilson Michael
- Wimalge P. M. S. N.
- Wogensen Fredrik
- Wolf Bernhard
- Wondoh Paul
- Wondoh Paul
- Wong Chui Yee
- Wong Francisca
- Wong Hong Yee
- Wood Greta
- Worku Mengistu
- Worku Tewodros
- Wright Naomi
- Yahaya Muhammad Taqiyuddin
- Yakubu Musah
- Yam Sir Young
- Yang James
- Yap Suhhuey
- Yau Jih Dar
- Ye Joselyn
- Yeang Li Jing
- Yeung Man Hon Andrew
- Yifieyeh Abiboye
- Yildirim Reyyan
- Yip Chingwan
- Ymeri Shpetim
- Yoganathan Pigeneswaren
- Yolcu Sinem
- Yong Guo Liang
- Younis Abobaker
- Youssef Mohamed
- Yuksek Mahmut Arif
- Yusufali Taha
- Zaa'treh Rula
- Zadoroznas Antanas
- Zahran Diaaaldin
- Zakaria Esraay
- Zakaria Mahmoud
- Zakaria Yehia
- Zaki Ahmed
- Zammit Stefan
- Zampitis Nikolaos
- Zani Augusto
- Zani Augusto
- Zanini Nicola
- Zapata Felipe
- Zarb Ciskje
- Zeta Solis Ludwing Alexander
- Zielinski Martin
- Zilinskas Justas
- Zilinskas Justas
- Zilinskas Justas
- Zilinskiene Reda
- Ziubryte Greta
- Zohair Ahmed
- Zuber Markus
- Zuk Grzegorz
- Zulkifli Athirah
- Zumbuhl Lucius
- Publication venue
- Elsevier
- Publication date
- 01/06/2003
- Field of study
BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London
Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study
- Author
- Aahlin Eirik Kjus
- Aamer Ahmed
- Aaniana Kenneth
- Ababneh Ali
- Abaliksta Tomas
- Abantanga Francis
- Abbas Athar
- Abbasy Jibran
- Abbo Olivier
- Abbott Tom
- Abbouch Meryem
- Abd El-Latif Nadia Khalid
- Abd Elkhalek Esraa
- Abd-Elmawla Manar
- Abdallah Emad
- Abdel-Aty Abdulrahman
- Abdel-Hameed Noran
- Abdel-Kader Sara Mahmoud
- Abdelaal Abdelaziz
- Abdelaty Mohamed
- Abdelazeam Anan Rady
- Abdelazim Galaleldin
- Abdelaziz Mohamed A
- Abdelbadeai Kholoud
- Abdelfatah Afnan
- Abdelhady Samar
- Abdelhamed Rasha
- Abdelhamid Amina
- Abdelhaq Aram
- Abdelkader Mostafa
- Abdelkader Omar
- Abdelkhalek Mohamed
- Abdelmageed Eman
- Abdelmotaleb Ibrahem
- Abdelraouf Ahmed Mahmoud
- Abdelrouf Doaa Maher
- Abdelshakour Mahmoud
- Abdrabou Abdulshafi Khaled
- Abdul-Latif Saiba
- Abdulaziz Hager
- Abdulaziz Mustafa
- Abdulbagi Omar
- Abdulhakeem Eman Mahmoud
- Abdullah Mohamed Abozed
- Abdullah Nik Azim Nik
- Abdullah Noha
- Abdullahi Lawal
- Abdurrazzaaq Abdussemiu
- Abem Owusu Emmanuel
- Abiola Olajide
- Aboelella Majed
- Aboelmagd Omnia
- Aboelsoud Moustafa R
- Aboul-Naga Mariam Saad
- Abouzaid Arwa
- Abu Qumbos Amjad
- Abu-toyour Maram
- Abubakr Marwan
- Abuowda Yousef
- Abuqwaider Eman
- Abusalem Lana
- Abushamleh Soha
- Ackom Eric
- Acquah Emmanuel
- Adam Ali
- Adam Nourhan
- Adamu Ahmed
- Adawi Ihdaa
- Adawi Mohammad
- Adebanjo Ademola
- Adebola Oluwaseyi
- Adedeji Adesina
- Adel Badr Eldin
- Adel Israa
- Adella Fidelis Jacklyn
- Adelshone Abdelrahman
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O
- Ademuyiwa Adesoji O
- Adenekan Babajide
- Adeniran James
- Adeniyi Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adeyeye Ademola
- Adeyeye Ademola
- Adhitama Novia
- Adil Muhammad
- Adisa Adewale O
- Adiyaman Can
- Adu-Aryee Niiarmah
- Afana Samah
- Agalianos Christos
- Agarwal Arnav
- Agarwal Arnav
- Agbedinu Kwabena
- Aglan Amro
- Aguado Suarez Nuria
- Aguilera Maria Lorena
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlonsou Germain
- Ahlqvist Sandra
- Ahlqvist Sandra
- Ahmed Asdaq
- Ahmed Ataa
- Ahmed Hayam
- Ahmed Hussien
- Ahmed Lopna Ahmed Mohamed
- Ahmed Sara
- Ahmed Saraibrahim
- Ahounou Ernest Yemalin Stephane
- Ajah Jonathan
- Ajai Olalekan
- Ajao Akinlabi
- Ajiboye Anthony
- Akoto Elliot
- Akpenyi Onyinye
- Al Amin Shadid
- Al Attar Samaa Mahmoud
- Al Barraw Fayez Elian
- Al Bastawis Fatema
- Al Meligy Amgad
- Al Rafati Ahmad Abdel Razaq
- Al Raouf Eman Abd
- Al Saied Ghiath
- Al Subaie Norah
- Al-Bahrani Ahmed
- Al-Buhaisi Alaa
- Al-Dakka Emad
- Al-faqawi Maha
- Al-farram Hadeel
- Al-khatib Ahmed
- Al-Marakby Dina
- Al-saqqa Sara
- Al-Saqqa Sara W
- Al-Slaibi Ibrahim
- Al-taher Taher
- AlaaelDein Shahinaz
- Alada Muslimat
- Alakaloko Felix
- Alaloul Enas
- Alamin Shadid
- Alamoudi Mohammed
- Albiety Adel
- Alcca Ticona Willy
- Alejos Bermudez Ysabel Esthefany
- Alexander Philip
- Alexander Philip
- Alexandre Challine
- Alghamdi Ahmed
- Alghamdi Mohammed Saleh A
- Alhady Khaled
- Alhammali Tariq
- Alhassan Basmah
- Alhazmi Wedyan
- Alherz Mohammad
- Ali Ahmed
- Ali Citra Dewi Mohd
- Ali Elsayed
- Ali Safia
- Ali Syed Abdul Wahhab Eusoffee Wan
- Ali Tebian Hassanein Ahmed
- Ali Wadah
- Alihonou Thierry
- Alis Halil
- Aliyu Halima
- Aliyu Mohammad
- Aliyu Shamsudeen
- Aljboor Khaled
- Aljiffry Murad
- Alkaaki Aroub
- Alkelani Muhammad
- Allam Meran
- Allam Yomna
- Alnaby Mohamed Hassab
- Alnusairat Aseel
- Alqahtani Saleh
- Alsaggaf Mohammed Ubaid
- Alser Osaid H
- Alshareef Reham
- Altaf Abdulmalik
- Altamimi Abdullah
- Altamimi Afnan
- Altamini Afnan
- Altarayra Marwa
- Altibi Ahmed
- Altinel Yuksel
- Altinel Yuksel
- Altwijri Abdulaziz
- Alvi Abdul Rehman
- Aly Mohammed Yahia Mohamed
- Alyacoubi Said
- Alyahya Reem
- Alzahrani Ahmed
- Aman Nowrin F
- Amandito Radhian
- Amandito Radhian
- Ambrona-Zafra David
- Amin Hager Abdul Aziz
- Amjad Mohammadasim
- Amoah Michael
- Amoako Joachim
- Amoako Philip Taah
- Amoako-Boateng Mabel
- Amole Isaac
- Amreia Mahmoud
- Anderson Frank
- Andika Ferry Fitriya Ayu
- Andreotti Dario
- Andress Cedar
- Andriola Valeria
- Ang Yun Lin
- Angelieri Daniele
- Anis Echaieb
- Ansaloni Luca
- Ansaloni Luca
- Ansaloni Luca
- Antezana Diego
- Anthoulakis Christos
- Antoniozzi Angelo
- Anwar Nourhan
- Anyanwu Lofty-John
- Aonzo Paolo
- Appeadu-Mensah William
- Appiah Eric Kofi
- Aquilino Fabrizio
- Arafa Omar
- Arafa Sara
- Arango Maria Clara Mendoza
- Arcudi Claudio
- Armellini Andrea
- Arnaud Alexis
- Arnaud Alexis Pierre
- Arshad Mohammad Mohsin
- Arslan Ekin
- Arsyad Hasbi Maulana
- Arthur Tom
- Aruldas Neerav
- Asar Yomna Hosny
- Asare-Bediako Kwasi
- Ashour Ahmad
- Ashour Ahmad
- Ashour Khlood
- Ashtari Morvarid
- Asi Fatema
- Asilah Siti Mohd Desa
- Assal Abdelrahman
- Asturias Sabrina
- Asumah Hamza
- Ata Ahmed
- Ata Aya Yehia
- Atiyeh Anwar
- Atkins Ebenezer Takyi
- Attia Attia
- Augestad Knut Magne
- Aviles Susan
- Avoka Anthony
- Awad Israa
- Awad Sawsan Adel
- Awadallah Salwa
- Ayandipo Omobolaji
- Aydin Mehmet Can
- Aziz Dayang Nita Abdul
- Aziz Mohamed Rezal Abdul
- Aziz Nora Abdul
- Azizeldine Mohammed G
- Azzie Georges
- Azzis Olivier
- Baba Suleiman
- Bachri Houda
- Badawy Mahmoud
- Badenjki Mohamed Adel
- Badicel Maria
- Badr Mohamed Fawzy Mahrous
- Badwi Nermin Mohamed
- Bahar Suraya
- Baillie Katie
- Baki Bahadir Emre
- Bakr Ahmad
- Bakry Hesham Mohammed
- Bala Miklosh
- Balalis Dimitrios
- Balducci Genoveffa
- Ballouhey Quentin
- Balmaceda Ruben
- Balmaceda Ruben
- Balogun Fatai
- Baltrunas Robertas
- Baluch Fatima
- Bamford Rebecca
- Bamicha Athanasia
- Banaitis Vincas Jonas
- Bandi Ashwath
- Bandoh Dickson
- Bani-Sadar Ahmad
- Banipal Gurpreet Singh
- Baquero Suarez Alibeth Andres
- Baraka Heba
- Barendegere Venerand
- Barkolias Christos
- Barmayehvar Behrad
- Barnabas Gandau Naa
- Barrios Emmanuel
- Basilico Silvia
- Basir Elissa Rifhan Mohd
- Bassem Monica
- Bassit Khalil Abdul
- Basso Stefano MM
- Bayram Sefa
- Beamon Mieshia
- Bedada Alemayehu Ginbo
- BediakoBowan Antoinette
- Bekhet Amira Hassan
- Bekhet Nada Mohamed
- Beleno Alvaro Enrique Mendoza
- Belkouchi Abdelkader
- Belli Andrea
- Bello Bashir
- Benammi Sarah
- Benevento Angelo
- Bennai Redouane Mammar
- Bentounsi Zineb
- Benyaiche Chaymae
- Berti Stefano
- Bertuello Isaac
- Beuran Mircea
- Bhangu Aneel
- Bhangu Aneel
- Bhangu Anna
- Bhatnagar Ankur
- Bhopal Kamran Faisal
- Bianco Federica
- Bigaran Annamaria
- Billy Matthew
- Bin Adnan Ahmad
- Bin Hasnan Muhammad
- Bin Ismail Mohamad Jeffrey
- Birindelli Arianna
- Bisset Carly
- Bjorklund Ida
- Blacker Sarah
- Blackwell James
- Blanco Ruth
- Blanco-Colino Ruth
- Blencowe Natalie
- Bliksoen Marte
- Bluelle Rafael
- Bocchetti Tommaso
- Bode Chris
- Bodur Selim
- Boggon Adam
- Bonavia Karl
- Bonavina Luigi
- Bond-Smith Giles
- Bondin John
- Bondurri Andrea
- Boni Silvia
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- Borda-Luque Giuliano
- Borg Elaine
- Borg Elaine
- Bortolasi Luca
- Bottini Corrado
- Bougard Heather
- Boukhal Khaoula
- Bowabsak Alaa
- Bowling Kirk
- Bradulskis Saulius
- Bratu Matei
- Bratu Matei Razvan
- Breaud Jean
- Breistrand Michaela
- Breslin Ryan
- Brincat Svetlana Doris
- Broch Aline
- Brunoni Beatrice
- Bsisu Isam
- Bucci Luigi
- Buisson Philippe
- Bunting David
- Burger Sule
- Burmistrovas Andrius
- Bustangi Nasir
- Bustangi Nasir
- Butt Muhammad Talha
- Cakaloglu Haluk Cem
- Caliman Celeste
- Callan Rory
- Camilleri Georgette Marie
- Camilleri-Brennan Julian
- Campagnaro Tommaso
- Canta Calua Alexander
- Capito Carmen
- Carabott Kurt
- Carmela Lapitan Marie
- Carmona Juan Manuel
- Carpio Juan
- Carrasco Nahilia
- Cassar Kristina
- Catani Marco
- Cautiero Roberto
- Caydiid Hanaan
- Cecilia Tolg
- Celik Saban
- Cengiz Turgut Bora
- Cengiz Yucel
- Cengiz Yucel
- Cevik Muazzez
- Chabok Abbas
- Chai Chu-Ann
- Chai Feng Yih
- Chan Luke
- Chan Tsz-Yan Katie
- Chan Xue Wei
- Charles Angeline
- Cheah Alvin Ee Zhiun
- Chen Kar Yan
- Chen Tzu-Ling
- Cheong Yih Jeng
- Chetta Nicola
- Cheung Yuk Hong Eric
- Chibuye Chali
- Chiesa Deborah
- Chilton Gareth
- Chin Pui Xin
- Chin Ye Ru
- Chiu Seehui
- Choi Philip
- Chong Choon Seng
- Chong Hoong-Yin
- Choudhry Asad
- Chow Crystal Yern Nee
- Chowdhury Debkumar
- Chu Kathryn
- Chung Kuet Jun
- Chungui Bravo Jorge Armando
- Ciccioli Eleonora
- Ciubotaru Cezar
- Claire Raquillet
- Clarissa Audrey
- Clegg-Lampety Joe-Nat
- Clegg-Lamptey Joe-Nat
- Clerico Giuseppe
- Coccolini Federico
- Coccolini Federico
- Cocorullo Gianfranco
- Cohen Fraser
- Cole Simon
- Coletta Diego
- Coletti Massimo
- Collaborative GlobalSurg
- Cona Camilla
- Conci Simone
- Confalonieri Gianmaria
- Conlon Kevin C
- Connor Katie
- Contreras Elisa
- Coompson Christian Lari
- Corbellini Carlo
- Corbellino Mario
- Cornick Jen
- Coronel Jazmin
- Corral Moreno Sara
- Correa Juan Camilo
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- Costa Cecilia
- Costa-Maia Jose
- Costas-Chavarri Ainhoa
- Courboin Etienne
- Cox Daniel
- Cox Michael
- Coyoy-Gaitan Otto
- Craus-Miguel Andrea
- Cullen Fraser
- Curletti Gianluca
- Currow Chelise
- D'Amours Scott
- D'Souza Michelle S
- Dabboor Majd
- Dabbour Kareem
- Dagoe Enoch
- Dahy Ahmed
- Dainius Edvinas
- Dakubo Jonathan
- Dalli Jeffrey
- Dally Charles
- Dambrauskas Zilvinas
- Daniyan Muhammad
- Danys Donatas
- Dao Weihei
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- Darwish Abdelrhman KZ
- Dasari Mohini
- Dashnyam Enkhbat
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- Dayie Makafui
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- Deal Rebecca
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- Dedekind Britta
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- Del Basso Celeste
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- Deutschmann Peter
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- Diaz-Jover Paula
- Dick Lachlan
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- Domini Edgar
- Donnelly Philippa
- Dorani Radin Mohd Nurrahman Radin
- Dorisme Asnel
- Dossou Francis
- Dousset Bertrand
- Dragatas Deividas
- Drake Thomas M
- Drake Thomas M
- Drungilas Mantas
- du Plooy Flip
- Du Toit Frederick
- Duane Therese
- Duinhouwer Lucia
- Dulskas Audrius
- Ebidy Mai
- Ebidy Mai Mohamed
- Eid Mostafa Mahmoud
- El Dahab Ali Abo
- El Gendy Noran Halim
- El Halawany Mohamed
- El Jamassi Alaa
- El Kashash Ahmed
- El Sayed Islam Magdy
- El-Dien Khalid Salah
- El-Din Reham Alaa
- El-Din Shahinaz Alaa
- El-Gizawy Esraa
- El-Sagheer Nada
- El-Sawy Aya
- El-Sehily Ahmed
- El-Taher Esraa
- Elashry Rehab
- Elazab Alaa
- Elbanby Esraa Samir
- Elbe Peter
- Elbisomy Khaled Hesham
- Eldafrawy Mahmoud
- Eldeeb Ahmed Zaki
- Eldeen Esraa Alm
- Eldin Mostafa Ahmed Bahaa
- Elebute Olumide
- Elfarargy Arwa
- Elfeki Hossam
- Elfiky Mahmoud
- Elfouly Nesma
- Elfouly Yasmin
- Elgendy Alyaa Halim
- Elgheriany Mohammed
- Elhadad Alaa
- Elhadary Nourhan Medhat
- Elhadry Shady
- Elhalawany Esraa
- Elhamouly Sara
- Elhelbawy Mohamed Salah
- Elhendawy Abdelaziz
- Elhoseny Ghada
- Elhusseiny Ahmed Abd Elmoen
- Elkholy Shimaa Said
- Ellison Quinn
- Elmashala Amjad
- Elmasry Maha
- Elmihy Sohaila
- Elnagar Ahmedglal
- Elnajjar Mahmoud A
- Elrazek Aly Abd
- Elsabbagh Nourhan
- Elsameea Ahmed Abd
- Elsawy Amira
- Elsayed Nada Ahmed Reda
- Elsemelawy Rofida
- Elshaar Mohammed
- Elshaer Mohamed
- Elshami Mohamedraed
- Elsharkawy Aya Adel
- Elsherbiney Saged
- Elsherif Fawzia Abdellatif
- Elwy Eman
- Elzahed Nada
- Emadeldin Hossam
- Emara Eman
- Emile Sameh
- Eng Calvin
- English William
- Esam Abeer
- Escalante Salas Marilia Del Carmen
- Espin-Basany Eloy
- Espinoza Fernando
- Essam AA
- Essam Ahmed
- Essam Mahitab
- Essoun Samuel
- Esteban Enrique
- Estee Mahnuma Mahfuz
- Etchill Eric
- Etienne Sara
- Etwire Victor
- Evajelista Cicilia Viany
- Evans David
- Evans Elizabeth
- Ezzat Eslam
- Ezzat Tarek
- Faboya Omolara
- Fahim Marwan
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- Falaschi Federica
- Falco Nicolo
- Falzon Malcolm
- Farag Ahmed
- Farag Sameh
- Farahat Mahitab Morsy
- Fares Mohamed
- Farhan-Alanie Muhamed MH
- Farhangmehr Neda
- Farouk Sara Amr Mohamed
- Farrugia Alexia
- Farrugia Alexia
- Faruq Amreen
- Fathy Aya Mohamed
- Fatuga Adedeji
- Faturoti Olubukola
- Favero Alessandro
- Feidantsis Thomas
- Fergany Alaa
- Fergusson Stuart J
- Fergusson Stuart J
- Fermani Claudio Gabriel
- Fernandes Cristina
- Fernandez Carmen
- Fernandez-Vega Laura
- Ferousis Christoforos
- Ferrero Esther
- Filatau Aliaksandr
- Firdouse Mohammed
- Firdouse Mohammed
- Firwana Aya
- Fitsum Agazi
- Fitzgerald J Edward
- Fitzgerald J Edward
- Florez Farfan Erick Samuel
- Foco Maurizio
- Fok Chi Ying Jacquelyn
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- Foo Chi Chung
- Forlin Louise
- Fouad Dina
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- Francisco Roxas Manuel
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- Francois Poddevin
- Francone Elisa
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- Gaafar Shireen
- Gaarder Tina
- Gad Ahmed
- Gad Mariam O
- Gadelkarim Mohamed
- Gado Ammar
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- Gala Tanzeela
- Galiqi Gezim
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- Trompetto Mario
- Tselos Angelos
- Tshisola Serge Kapenda
- Tugnoli Gregorio
- Tun Myint
- Turati Luca
- Turkustani Sondos
- Turpo Espinoza Kenny
- Turpo Espinoza Kevin
- Tutino Roberta
- Tverskis Zygimantas
- Tyler Robert
- Tze R Goh Ern
- Tzikos Georgios
- Ubiali Paolo
- Ukwenya Yahaya
- ul Razi Syed Asaat
- Ulusahin Mehmet
- Upadhyaya Vijaid
- Urbonas Tomas
- Urniezius Zigmantas
- Uscinas Laimonas
- Uzabumwana Norbert
- Vaicius Arturas
- Valcarcel-Saldana Maria
- Valioulis Ioannis
- Van Der Naald Niels
- Van Niekerk Michael
- Van Straten Stephanie
- Vargas Marvin
- Vartanoglu Talar
- Vartic Mihaela
- Vasquez Giorgio
- Vasquez Idelso
- Veen Torhild
- Velasquez Ricardo
- Venclauskas Linas
- Vendramin Elena
- Venskutonis Donatas
- Venskutonis Donatas
- Verbeek Anna
- Vergara Mejia Angelica Genoveva
- Verjee Azmina
- Vermaas Maarten
- Vicario Erika
- Vicenta Collado Maria
- Vida Lucian Corneliu
- Vilcinskas Mantas
- Villalobos Santiago
- Violi Paola
- Visinskas Petras
- Voulgaris Evangelos
- Wael Noha
- Wakefield Rebecca
- Waledziak Maciej
- Walker Michael
- Walker Nathan
- Walls Luke
- Walsh Michael
- Waqar Muhammad
- Warren Oliver
- Waterman Ade
- Werder Gabriela
- Whitaker John
- White Rebecca
- Whitehurst Katharine
- Wiborg Joachim
- Widiastini T Ariani
- Widmer Lukas Werner
- Wijayarathna LS
- Williams Omolara
- Wilson Ling
- Wilson Michael
- Wilson Michael
- Wimalge PMSN
- Wogensen Fredrik
- Wolf Bernhard
- Wondoh Paul
- Wondoh Paul
- Wong Chui Yee
- Wong Francisca
- Wong Hong Yee
- Wood Greta
- Worku Mengistu
- Worku Tewodros
- Wright Naomi
- Yahaya Muhammad Taqiyuddin
- Yakubu Musah
- Yam Sir Young
- Yang James
- Yap Suhhuey
- Yau Jih Dar
- Ye Joselyn
- Yeang Li Jing
- Yeung Man Hon Andrew
- Yifieyeh Abiboye
- Yildirim Reyyan
- Yip Chingwan
- Ymeri Shpetim
- Yoganathan Pigeneswaren
- Yolcu Sinem
- Yong Guo Liang
- Younis Abobaker
- Youssef Mohamed
- Yuksek Mahmut Arif
- Yusufali Taha
- Zaa'treh Rula
- Zadoroznas Antanas
- Zahran Diaaaldin
- Zakaria Esraay
- Zakaria Mahmoud
- Zakaria Yehia
- Zaki Ahmed
- Zammit Stefan
- Zampitis Nikolaos
- Zani Augusto
- Zani Augusto
- Zanini Nicola
- Zapata Felipe
- Zarb Ciskje
- Zeta Solis Ludwing Alexander
- Zielinski Martin
- Zilinskas Justas
- Zilinskas Justas
- Zilinskas Justas
- Zilinskiene Reda
- Ziubryte Greta
- Zohair Ahmed
- Zuber Markus
- Zuk Grzegorz
- Zulkifli Athirah
- Zumbuhl Lucius
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2018
- Field of study
Background: Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world.
Methods: This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231.
Findings: Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p < 0·001). The highest SSI incidence in each HDI group was after dirty surgery (102 [17·8%] of 574 patients in high-HDI countries; 74 [31·4%] of 236 patients in middle-HDI countries; 72 [39·8%] of 181 patients in low-HDI countries). Following risk factor adjustment, patients in low-HDI countries were at greatest risk of SSI (adjusted odds ratio 1·60, 95% credible interval 1·05–2·37; p=0·030). 132 (21·6%) of 610 patients with an SSI and a microbiology culture result had an infection that was resistant to the prophylactic antibiotic used. Resistant infections were detected in 49 (16·6%) of 295 patients in high-HDI countries, in 37 (19·8%) of 187 patients in middle-HDI countries, and in 46 (35·9%) of 128 patients in low-HDI countries (p < 0·001).
Interpretation: Countries with a low HDI carry a disproportionately greater burden of SSI than countries with a middle or high HDI and might have higher rates of antibiotic resistance. In view of WHO recommendations on SSI prevention that highlight the absence of high-quality interventional research, urgent, pragmatic, randomised trials based in LMICs are needed to assess measures aiming to reduce this preventable complication
The global burden of adolescent and young adult cancer in 2019 : a systematic analysis for the Global Burden of Disease Study 2019
- Author
- Abbasi Behzad
- Abbasi-Kangevari Mohsen
- Abbasi-Kangevari Zeinab
- Abbastabar Hedayat
- Abd-Elsalam Sherief
- Abdelmasseh Michael
- Abdoli Amir
- Abebe Haimanot
- Abedi Aidin
- Abidi Hassan
- Abolhassani Hassan
- Abu-Gharbieh Eman
- Abubaker Ali Hiwa
- Achappa Basavaprabhu
- Acuna Juan Manuel
- Adedeji Isaac Akinkunmi
- Adegboye Oyelola A
- Adnani Qorinah Estiningtyas Sakilah
- Advani Shailesh M
- Afzal Muhammad Sohail
- Aghaie Meybodi Mohamad
- Ahadinezhad Bahman
- Ahinkorah Bright Opoku
- Ahmad Sajjad
- Ahmadi Sepideh
- Ahmed Rashid Tarik
- Ahmed Salih Yusra
- Ahmed Muktar Beshir
- Aiman Wajeeha
- Akalu Gizachew Taddesse
- Al Hamad Hanadi
- Al-Maweri Sadeq Ali
- Al-Raddadi Rajaa M
- Alahdab Fares
- AlAmodi Abdulhadi A
- Alanezi Fahad Mashhour
- Alanzi Turki M
- Alem Adugnaw Zeleke
- Alem Dejene Tsegaye
- Alemayehu Yosef
- Alhalaiqa Fadwa Naji
- Alhassan Robert Kaba
- Ali Saqib
- Alicandro Gianfranco
- Alipour Vahid
- Aljunid Syed Mohamed
- Alkhayyat Motasem
- Alluri Sunitha
- Almasri Nihad A
- Almustanyir Sami
- Alvarez Elysia M
- Alvis-Guzman Nelson
- Ameyaw Edward Kwabena
- Amini Saeed
- Amu Hubert
- Ancuceanu Robert
- Andrei Catalina Liliana
- Andrei Tudorel
- Ansari Fereshteh
- Ansari-Moghaddam Alireza
- Anvari Davood
- Anyasodor Anayochukwu Edward
- Arab-Zozani Morteza
- Arabloo Jalal
- Argaw Ayele Mamo
- Ariffin Hany
- Arshad Muhammad
- Arulappan Judie
- Aryannejad Armin
- Asemi Zatollah
- Asghari Jafarabadi Mohammad
- Atashzar Mohammad Reza
- Atorkey Prince
- Atreya Alok
- Attia Sameh
- Aujayeb Avinash
- Ausloos Marcel
- Avila-Burgos Leticia
- Awedew Atalel Fentahun
- Ayala Quintanilla Beatriz Paulina
- Ayele Alemu Degu
- Ayen Solomon Shitu
- Azab Mohammed A
- Azadnajafabad Sina
- Azami Hiva
- Azangou-Khyavy Mohammadreza
- Azari Jafari Amirhossein
- Azarian Ghasem
- Azzam Ahmed Y
- Bahadory Saeed
- Bai Jianjun
- Baig Atif Amin
- Baker Jennifer L
- Banach Maciej
- Barone-Adesi Francesco
- Barr Ronald D
- Barra Fabio
- Barrow Amadou
- Basaleem Huda
- Batiha Abdul-Monim Mohammad
- Behzadifar Masoud
- Bekele Niguss Cherie
- Belete Rebuma
- Belgaumi Uzma Iqbal
- Bell Arielle Wilder
- Berhie Alemshet Yirga
- Bhagat Devidas S
- Bhagavathula Akshaya Srikanth
- Bhakta Nickhill
- Bhardwaj Nikha
- Bhardwaj Pankaj
- Bhaskar Sonu
- Bhattacharyya Krittika
- Bhojaraja Vijayalakshmi S
- Bibi Sadia
- Bijani Ali
- Biondi Antonio
- Birara Setognal
- Bjørge Tone
- Bleyer Archie
- Bolarinwa Obasanjo Afolabi
- Bolla Srinivasa Rao
- Boloor Archith
- Braithwaite Dejana
- Brenner Hermann
- Bulamu Norma B
- Burkart Katrin
- Bustamante-Teixeira Maria Teresa
- Butt Nadeem Shafique
- Butt Zahid A
- Bärnighausen Till Winfried
- C. La Vecchia
- Caetano dos Santos Florentino Luciano
- Cao Chao
- Cao Yin
- Carreras Giulia
- Catalá-López Ferrán
- Cembranel Francieli
- Cerin Ester
- Chakinala Raja Chandra
- Chakraborty Promit Ananyo
- Chattu Vijay Kumar
- Chaturvedi Pankaj
- Chaurasia Akhilanand
- Chavan Prachi P
- Chimed-Ochir Odgerel
- Choi Jee-Young Jasmine
- Christopher Devasahayam J
- Chu Dinh-Toi
- Chung Michael T
- Compton Kelly
- Conde Joao
- Costa Vera Marisa
- D'Amico Emanuele
- Da'ar Omar B
- Dadras Omid
- Dahlawi Saad M A
- Dai Xiaochen
- Damiani Giovanni
- Dandona Lalit
- Dandona Rakhi
- Daneshpajouhnejad Parnaz
- Darwish Amira Hamed
- Daryani Ahmad
- De la Hoz Fernando Pio
- Dean Frances E
- Debela Sisay Abebe
- Demie Takele Gezahegn G
- Demissie Getu Debalkie
- Demissie Zeleke Geto
- Denova-Gutiérrez Edgar
- Derbew Molla Meseret
- Desai Rupak
- Desta Abebaw Alemayehu
- Dhamnetiya Deepak
- Dharmaratne Samath Dhamminda
- Dhimal Mandira Lamichhane
- Dhimal Meghnath
- Dianatinasab Mostafa
- Didehdar Mojtaba
- Diress Mengistie
- Djalalinia Shirin
- Do Huyen Phuc
- Doaei Saeid
- Dorostkar Fariba
- dos Santos Wendel Mombaque
- Drake Thomas M
- Ekholuenetale Michael
- El Sayed Zaki Maysaa
- El Sayed Iman
- El Tantawi Maha
- El-Abid Hassan
- El-Jaafary Shaimaa I
- Elbahnasawy Mostafa Ahmed
- Elbarazi Iffat
- Elhabashy Hala Rashad
- Elhadi Muhammed
- Enyew Daniel Berhanie
- Erdomaeva Yana Arturovna
- Erkhembayar Ryenchindorj
- Eshrati Babak
- Eskandarieh Sharareh
- Faisaluddin Mohammed
- Fares Jawad
- Farooque Umar
- Fasanmi Abidemi Omolara
- Fatima Wafa
- Ferreira de Oliveira José Miguel P
- Ferrero Simone
- Ferro Desideri Lorenzo
- Fetensa Getahun
- Filip Irina
- Fischer Florian
- Fisher James L
- Fitzmaurice Christina
- Force Lisa M
- Foroutan Masoud
- Fu Weijia
- Fukumoto Takeshi
- Gaal Peter Andras
- Gad Mohamed M
- Gaewkhiew Piyada
- Gallus Silvano
- Garg Tushar
- Gebremeskel Teferi Gebru
- Gemeda Belete Negese Belete
- Getachew Tamiru
- Ghafourifard Mansour
- Ghamari Seyyed-Hadi
- Ghashghaee Ahmad
- Ghassemi Fariba
- Ghith Nermin
- Gholami Ali
- Gholizadeh Navashenaq Jamshid
- Gilani Syed Amir
- Ginindza Themba G
- Gizaw Abraham Tamirat
- Glasbey James C
- Goel Amit
- Golechha Mahaveer
- Goleij Pouya
- Golinelli Davide
- Gopalani Sameer Vali
- Gorini Giuseppe
- Goudarzi Houman
- Goulart Bárbara Niegia Garcia
- Grada Ayman
- Gubari Mohammed Ibrahim Mohialdeen
- Guerra Maximiliano Ribeiro
- Guha Avirup
- Gunasekera D Sanjeeva
- Gupta Bhawna
- Gupta Sapna
- Gupta Veer Bala
- Gupta Vivek Kumar
- Haddadi Rasool
- Hafezi-Nejad Nima
- Hailu Alemayehu
- Haj-Mirzaian Arvin
- Halwani Rabih
- Hamadeh Randah R
- Hambisa Mitiku Teshome
- Hameed Sajid
- Hamidi Samer
- Haque Shafiul
- Hariri Sanam
- Haro Josep Maria
- Harvey James D
- Hasaballah Ahmed I
- Hasan S M Mahmudul
- Hashemi Seyedeh Melika
- Hassan Treska S
- Hassanipour Soheil
- Hay Simon I
- Hayat Khezar
- Hebo Sultan H
- Heidari Golnaz
- Heidari Mohammad
- Henrikson Hannah Jacqueline
- Herrera-Serna Brenda Yuliana
- Herteliu Claudiu
- Heyi Demisu Zenbaba
- Hezam Kamal
- Hole Michael K
- Holla Ramesh
- Horita Nobuyuki
- Hossain Md Mahbub
- Hossain Mohammad Bellal
- Hosseini Mohammad-Salar
- Hosseini Mostafa
- Hosseinzadeh Ali
- Hosseinzadeh Mehdi
- Hostiuc Mihaela
- Hostiuc Sorin
- Househ Mowafa
- Hsairi Mohamed
- Huang Junjie
- Hussein Nawfal R
- Hwang Bing-Fang
- Ibitoye Segun Emmanuel
- Ilesanmi Olayinka Stephen
- Ilic Irena M
- Ilic Milena D
- Innos Kaire
- Irham Lalu Muhammad
- Islam Rakibul M
- Islam Sheikh Mohammed Shariful
- Ismail Nahlah Elkudssiah
- Isola Gaetano
- Iwagami Masao
- Jacob Louis
- Jadidi-Niaragh Farhad
- Jain Vardhmaan
- Jakovljevic Mihajlo
- Janghorban Roksana
- Javadi Mamaghani Amirreza
- Jayaram Shubha
- Jayawardena Ranil
- Jazayeri Seyed Behzad
- Jebai Rime
- Jha Ravi Prakash
- John-Akinola Yetunde O
- Joo Tamas
- Joseph Nitin
- Joukar Farahnaz
- Jürisson Mikk
- Kaambwa Billingsley
- Kabir Ali
- Kalankesh Leila R
- Kaliyadan Feroze
- Kamal Zul
- Kamath Ashwin
- Kandel Himal
- Kar Sitanshu Sekhar
- Karaye Ibraheem M
- Karimi Amirali
- Kassa Bekalu Getnet
- Kauppila Joonas H
- Keegan Theresa H M
- Kemp Bohan Phillip M
- Kengne Andre Pascal
- Kerbo Amene Abebe
- Ketterl Tyler G
- Keykhaei Mohammad
- Khader Yousef Saleh
- Khajuria Himanshu
- Khalili Nastaran
- Khalili Neda
- Khan Ejaz Ahmad
- Khan Gulfaraz
- Khan Maseer
- Khan Md Nuruzzaman
- Khan Moien AB
- Khanali Javad
- Khayamzadeh Maryam
- Khosravizadeh Omid
- Khubchandani Jagdish
- Khundkar Roba
- Kim Min Seo
- Kim Yun Jin
- Kisa Adnan
- Kisa Sezer
- Kissimova-Skarbek Katarzyna
- Kocarnik Jonathan M
- Kolahi Ali-Asghar
- Kopec Jacek A
- Koteeswaran Rajasekaran
- Koulmane Laxminarayana Sindhura Lakshmi
- Koyanagi Ai
- Kugbey Nuworza
- Kumar G Anil
- Kumar Nithin
- Kutluk Tezer
- Kwarteng Alexander
- Lan Qing
- Landires Iván
- Lasrado Savita
- Lauriola Paolo
- Ledda Caterina
- Lee Sang-woong
- Lee Wei-Chen
- Lee Yeong Yeh
- Lee Yo Han
- Leigh James
- Leong Elvynna
- Li Bingyu
- Li Jiarui
- Li Ming-Chieh
- Lim Stephen S
- Liu Xuefeng
- Lobo Stany W
- Loureiro Joana A
- Lu Dan
- Lugo Alessandra
- Lunevicius Raimundas
- Magdy Abd El Razek Hassan
- Magdy Abd El Razek Muhammed
- Mahmoudi Morteza
- Majeed Azeem
- Makki Alaa
- Male Shilpa
- Malekpour Mohammad-Reza
- Malekzadeh Reza
- Malik Ahmad Azam
- Malogolowkin Marcio Henrique
- Mamun Mohammed A
- Manafi Navid
- Mansour-Ghanaei Fariborz
- Mansouri Borhan
- Mansournia Mohammad Ali
- Martini Santi
- Masoumi Seyedeh Zahra
- Matei Clara N
- Mathur Manu Raj
- Mathur Prashant
- McAlinden Colm
- Mehrotra Ravi
- Mendoza Walter
- Menezes Ritesh G
- Mentis Alexios-Fotios A
- Meretoja Tuomo J
- Mersha Amanual Getnet
- Mesregah Mohamed Kamal
- Mestrovic Tomislav
- Miao Jonasson Junmei
- Miazgowski Bartosz
- Michalek Irmina Maria
- Miller Ted R
- Mingude Alemu Basazin
- Mirmoeeni Seyyedmohammadsadeq
- Mirzaei Hamed
- Misra Sanjeev
- Mithra Prasanna
- Mohammad Karzan Abdulmuhsin
- Mohammadi Mokhtar
- Mohammadi Seyyede Momeneh
- Mohammadian-Hafshejani Abdollah
- Mohammadpourhodki Reza
- Mohammed Arif
- Mohammed Shafiu
- Mohammed Teroj Abdulrahman
- Moka Nagabhishek
- Mokdad Ali H
- Molokhia Mariam
- Momtazmanesh Sara
- Monasta Lorenzo
- Moni Mohammad Ali
- Moradi Ghobad
- Moradi Yousef
- Moradzadeh Maliheh
- Moradzadeh Rahmatollah
- Moraga Paula
- Morrison Shane Douglas
- Mostafavi Ebrahim
- Mousavi Khaneghah Amin
- Mpundu-Kaambwa Christine
- Mubarik Sumaira
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- Mwanri Lillian
- Nabhan Ashraf F
- Nagaraju Shankar Prasad
- Nagata Chie
- Naghavi Mohsen
- Naimzada Mukhammad David
- Naldi Luigi
- Nangia Vinay
- Naqvi Atta Abbas
- Narasimha Swamy Sreenivas
- Narayana Aparna Ichalangod
- Nayak Biswa Prakash
- Nayak Vinod C
- Nazari Javad
- Nduaguba Sabina Onyinye
- Negoi Ionut
- Negru Serban Mircea
- Nejadghaderi Seyed Aria
- Nepal Samata
- Neupane Kandel Sandhya
- Nggada Haruna Asura
- Nguyen Cuong Tat
- Nnaji Chukwudi A
- Nosrati Hamed
- Nouraei Hasti
- Nowroozi Ali
- Nuñez-Samudio Virginia
- Nwatah Vincent Ebuka
- Nzoputam Chimezie Igwegbe
- Oancea Bogdan
- Odukoya Oluwakemi Ololade
- Oguntade Ayodipupo Sikiru
- Oh In-Hwan
- Olagunju Andrew T
- Olagunju Tinuke O
- Olakunde Babayemi Oluwaseun
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- Omar Emad
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- Onwujekwe Obinna E
- Ortega-Altamirano Doris V
- Otstavnov Nikita
- Otstavnov Stanislav S
- Oumer Bilcha
- Owolabi Mayowa O
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- Padron-Monedero Alicia
- Padubidri Jagadish Rao
- Pakshir Keyvan
- Pana Adrian
- Pandey Anamika
- Pardhan Shahina
- Pashazadeh Kan Fatemeh
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- Pulakunta Thejodhar
- Qadir Mirza Muhammad Fahd Fahd
- Rabiee Mohammad
- Rabiee Navid
- Radfar Amir
- Radhakrishnan Raghu Anekal
- Radhakrishnan Venkatraman
- Rafiee Ata
- Rafiei Alireza
- Rafiei Sima
- Rahim Fakher
- Rahimzadeh Shadi
- Rahman Mosiur
- Rahman Muhammad Aziz
- Rahmani Amir Masoud
- Rajesh Aashish
- Ramezani-Doroh Vajiheh
- Ranabhat Kamal
- Ranasinghe Priyanga
- Rao Chythra R
- Rao Sowmya J
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- Rashidi Mohammad-Mahdi
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- Razeghinia Mohammad Sadegh
- Regasa Misganu Teshoma
- Renzaho Andre M N
- Rezaei Maryam
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- Rezaei Nima
- Rezaeian Mohsen
- Rezapour Aziz
- Rezazadeh-Khadem Sahba
- Riad Abanoub
- Ries Lynn Ann Gloeckler
- Rios Lopez Ligia Estefania
- Rodriguez Jefferson Antonio Buendia
- Rodriguez-Galindo Carlos
- Ronfani Luca
- Roshandel Gholamreza
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- Saber-Ayad Maha Mohamed
- Sabour Siamak
- Saddik Basema
- Sadeghi Erfan
- Sadeghian Saeid
- Saeed Umar
- Sagoyan Garik Barisovich
- Sahebkar Amirhossein
- Saif-Ur-Rahman KM
- Sajadi S Mohammad
- Salahi Sarvenaz
- Salehi Sana
- Salem Marwa Rashad
- Salimzadeh Hamideh
- Samy Abdallah M
- Sanabria Juan
- Sanmarchi Francesco
- Sarveazad Arash
- Sathian Brijesh
- Sawhney Monika
- Sawyer Susan M
- Saylan Mete
- Schneider Ione Jayce Ceola
- Seidu Abdul-Aziz
- Sendo Endalew Gemechu
- Sepanlou Sadaf G
- Seylani Allen
- Seyoum Kenbon
- Sha Feng
- Shafaat Omid
- Shaikh Masood Ali
- Shamsoddin Erfan
- Shannawaz Mohammed
- Sharma Rajesh
- Sheikhbahaei Sara
- Shetty Adithi
- Shetty B Suresh Kumar
- Shetty Pavanchand H
- Shin Jae Il
- Shirkoohi Reza
- Shivakumar K M
- Shobeiri Parnian
- Siabani Soraya
- Sibhat Migbar Mekonnen
- Siddappa Malleshappa Sudeep K
- Sidemo Negussie Boti
- Silva Julian Guilherme
- Silva Diego Augusto Santos
- Singh Achintya Dinesh
- Singh Jasvinder A
- Singh Jitendra Kumar
- Singh Surjit
- Sinke Abiy H
- Sintayehu Yitagesu
- Skryabin Valentin Yurievich
- Skryabina Anna Aleksandrovna
- Smith Lee
- Sofi-Mahmudi Ahmad
- Soltani-Zangbar Mohammad Sadegh
- Song Suhang
- Spurlock Emma Elizabeth
- Steiropoulos Paschalis
- Straif Kurt
- Subedi Ranjeeta
- Sufiyan Mu'awiyyah Babale
- Suliankatchi Abdulkader Rizwan
- Sultan Iyad
- Sultana Saima
- Szerencsés Viktória
- Szócska Miklós
- Tabaeian Seidamir Pasha
- Tabary Mohammadreza
- Tabarés-Seisdedos Rafael
- Tabuchi Takahiro
- Tadbiri Hooman
- Taheri Majid
- Taherkhani Amir
- Takahashi Ken
- Tampa Mircea
- Tan Ker-Kan
- Tat Vivian Y
- Tavakoli Ahmad
- Tbakhi Abdelghani
- Tehrani-Banihashemi Arash
- Temsah Mohamad-Hani
- Tesfay Fisaha Haile
- Tesfaye Bekele
- Thakur Jarnail Singh
- Thapar Rekha
- Thavamani Aravind
- Thiyagarajan Arulmani
- Thomas Nihal
- Tobe-Gai Ruoyan
- Togtmol Munkhsaikhan
- Tohidast Seyed Abolfazl
- Tohidinik Hamid Reza
- Tolani Musliu Adetola
- Tollosa Daniel Nigusse
- Touvier Mathilde
- Tovani-Palone Marcos Roberto
- Traini Eugenio
- Tran Bach Xuan
- Tran Mai Thi Ngoc
- Tripathy Jaya Prasad
- Tusa Biruk Shalmeno
- Ukke Gebresilasea Gendisha
- Ullah Irfan
- Ullah Saif
- Umapathi Krishna Kishore
- Unnikrishnan Bhaskaran
- Upadhyay Era
- Ushula Tolassa Wakayo
- Vacante Marco
- Valadan Tahbaz Sahel
- Vargas Martina T
- Varthya Shoban Babu
- Veroux Massimiliano
- Villeneuve Paul J
- Violante Francesco S
- Vlassov Vasily
- Vu Giang Thu
- Waheed Yasir
- Wang Ning
- Ward Paul
- Weldesenbet Adisu Birhanu
- Wen Yi Feng
- Westerman Ronny
- Winkler Andrea Sylvia
- Wubishet Befikadu Legesse
- Xu Rixing
- Xu Suowen
- Yahyazadeh Jabbari Seyed Hossein
- Yang Lin
- Yaya Sanni
- Yazdi-Feyzabadi Vahid
- Yazie Taklo Simeneh
- Yehualashet Sisay Shewasinad
- Yeshaneh Alex
- Yeshaw Yigizie
- Yirdaw Birhanu Wubale
- Yonemoto Naohiro
- Younis Mustafa Z
- Yousefi Zabihollah
- Yu Chuanhua
- Yunusa Ismaeel
- Zadnik Vesna
- Zahir Mazyar
- Zahirian Moghadam Telma
- Zamani Mohammad
- Zamanian Maryam
- Zandian Hamed
- Zare Fariba
- Zastrozhin Mikhail Sergeevich
- Zastrozhina Anasthasia
- Zhang Jianrong
- Zhang Zhi-Jiang
- Ziapour Arash
- Zoladl Mohammad
- Šekerija Mario
- Publication venue
- Publication date
- 01/01/2021
- Field of study
Background In estimating the global burden of cancer, adolescents and young adults with cancer are often overlooked, despite being a distinct subgroup with unique epidemiology, clinical care needs, and societal impact. Comprehensive estimates of the global cancer burden in adolescents and young adults (aged 15-39 years) are lacking. To address this gap, we analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, with a focus on the outcome of disability-adjusted life-years (DALYs), to inform global cancer control measures in adolescents and young adults. Methods Using the GBD 2019 methodology, international mortality data were collected from vital registration systems, verbal autopsies, and population-based cancer registry inputs modelled with mortality-to-incidence ratios (MIRs). Incidence was computed with mortality estimates and corresponding MIRs. Prevalence estimates were calculated using modelled survival and multiplied by disability weights to obtain years lived with disability (YLDs). Years of life lost (YLLs) were calculated as age-specific cancer deaths multiplied by the standard life expectancy at the age of death. The main outcome was DALYs (the sum of YLLs and YLDs). Estimates were presented globally and by Socio-demographic Index (SDI) quintiles (countries ranked and divided into five equal SDI groups), and all estimates were presented with corresponding 95% uncertainty intervals (UIs). For this analysis, we used the age range of 15-39 years to define adolescents and young adults. Findings There were 1.19 million (95% UI 1.11-1.28) incident cancer cases and 396 000 (370 000-425 000) deaths due to cancer among people aged 15-39 years worldwide in 2019. The highest age-standardised incidence rates occurred in high SDI (59.6 [54.5-65.7] per 100 000 person-years) and high-middle SDI countries (53.2 [48.8-57.9] per 100 000 person-years), while the highest age-standardised mortality rates were in low-middle SDI (14.2 [12.9-15.6] per 100 000 person-years) and middle SDI (13.6 [12.6-14.8] per 100 000 person-years) countries. In 2019, adolescent and young adult cancers contributed 23.5 million (21.9-25.2) DALYs to the global burden of disease, of which 2.7% (1.9-3.6) came from YLDs and 97.3% (96.4-98.1) from YLLs. Cancer was the fourth leading cause of death and tenth leading cause of DALYs in adolescents and young adults globally. Interpretation Adolescent and young adult cancers contributed substantially to the overall adolescent and young adult disease burden globally in 2019. These results provide new insights into the distribution and magnitude of the adolescent and young adult cancer burden around the world. With notable differences observed across SDI settings, these estimates can inform global and country-level cancer control efforts. Copyright (C) 2021 The Author(s). Published by Elsevier Ltd.Peer reviewe
The global burden of cancer attributable to risk factors, 2010-19 : a systematic analysis for the Global Burden of Disease Study 2019
- Author
- Aali Amirali
- Abbas Qamar
- Abbasi Behzad
- Abbasi-Kangevari Mohsen
- Abbasi-Kangevari Zeinab
- Abbastabar Hedayat
- Abd-Elsalam Sherief
- Abdelmasseh Michael
- Abdelwahab Ahmed Abdelwahab
- Abdoli Gholamreza
- Abdulkader Rizwan Suliankatchi
- Abdulkadir Hanan Abdulkadir
- Abedi Aidin
- Abegaz Kedir Hussein
- Abidi Hassan
- Aboagye Richard Gyan
- Abolhassani Hassan
- Absalan Abdorrahim
- Abtew Yonas Derso
- Abu-Gharbieh Eman
- Achappa Basavaprabhu
- Acheson Alistair R
- Acuna Juan Manuel
- Addison Daniel
- Addo Isaac Yeboah
- Adegboye Oyelola A
- Adesina Miracle Ayomikun
- Adnan Mohammad
- Adnani Qorinah Estiningtyas Sakilah
- Advani Shailesh M
- Afrin Sumia
- Afzal Muhammad Sohail
- Aggarwal Manik
- Ahinkorah Bright Opoku
- Ahmad Araz Ramazan
- Ahmad Rizwan
- Ahmad Sajjad
- Ahmad Sohail
- Ahmadi Sepideh
- Ahmed Haroon
- Ahmed Luai A
- Ahmed Muktar Beshir
- Aiman Wajeeha
- Ajami Marjan
- Akalu Gizachew Taddesse
- Akbarzadeh-Khiavi Mostafa
- Aklilu Addis
- Akonde Maxwell
- Akunna Chisom Joyqueenet
- Al-Hanawi Mohammed Khaled
- Al-Maweri Sadeq Ali Ali
- Al-Raddadi Rajaa M
- Al-Rifai Rami H Hani
- Al-Sabah Salman Khalifah
- Al-Tammemi Ala'a B
- Alahdab Fares
- Alanezi Fahad Mashhour
- Alanzi Turki M
- Alessy Saleh Ali
- Algammal Abdelazeem M
- Alhassan Robert Kaba
- Ali Adel Hajj
- Ali Beriwan Abdulqadir
- Ali Hiwa Abubaker
- Ali Liaqat
- Ali Syed Shujait
- Alimohamadi Yousef
- Alipour Vahid
- Aljunid Syed Mohamed
- Alkhayyat Motasem
- Almustanyir Sami
- Alonso Nivaldo
- Alqalyoobi Shehabaldin
- Altawalah Haya
- Alvis-Guzman Nelson
- Amare Firehiwot
- Ameyaw Edward Kwabena
- Amirzade-Iranaq Mohammad Hosein
- Amu Hubert
- Amusa Ganiyu Adeniyi
- Ancuceanu Robert
- Anderson Jason A
- Animut Yaregal Animut
- Anoushiravani Amir
- Anoushirvani Ali Arash
- Ansari-Moghaddam Alireza
- Ansha Mustafa Geleto
- Antony Benny
- Antwi Maxwell Hubert
- Anwar Sumadi Lukman
- Anwer Razique
- Anyasodor Anayochukwu Edward
- Arab-Zozani Morteza
- Arabloo Jalal
- Aremu Olatunde
- Argaw Ayele Mamo
- Ariffin Hany
- Aripov Timur
- Arshad Muhammad
- Artaman Al
- Arulappan Judie
- Aruleba Raphael Taiwo
- Aryannejad Armin
- Asaad Malke
- Asemahagn Mulusew A
- Asemi Zatollah
- Asghari-Jafarabadi Mohammad
- Ashraf Tahira
- Assadi Reza
- Athar Mohammad
- Athari Seyyed Shamsadin
- Atout Maha Moh'd Wahbi
- Attia Sameh
- Aujayeb Avinash
- Ausloos Marcel
- Avila-Burgos Leticia
- Avval Atlas Haddadi
- Awedew Atalel Fentahun
- Awoke Mamaru Ayenew
- Awoke Tewachew
- Ayana Tegegn Mulatu
- Ayen Solomon Shitu
- Azadi Davood
- Azadnajafabad Sina
- Azami-Aghdash Saber
- Azanaw Melkalem Mamuye
- Azangou-Khyavy Mohammadreza
- Azizi Hosein
- Azzam Ahmed YY
- Babajani Amirhesam
- Badar Muhammad
- Badiye Ashish D
- Baghcheghi Nayereh
- Bagheri Nader
- Bagherieh Sara
- Bahadory Saeed
- Baig Atif Amin
- Bain Luchuo Engelbert
- Baker Jennifer L
- Bakhtiari Ahad
- Bakshi Ravleen Kaur
- Banach Maciej
- Banerjee Indrajit
- Bardhan Mainak
- Barone-Adesi Francesco
- Barra Fabio
- Barrow Amadou
- Bashir Nasir Z
- Bashiri Azadeh
- Basu Saurav
- Batiha Abdul-Monim Mohammad
- Begum Aeysha
- Bekele Alehegn Bekele
- Belay Alemayehu Sayih
- Belete Melaku Ashagrie
- Belgaumi Uzma Iqbal
- Bell Arielle Wilder
- Belo Luis
- Benzian Habib
- Berhie Alemshet Yirga
- Bermudez Amiel Nazer C
- Bernabe Eduardo
- Bhagavathula Akshaya Srikanth
- Bhala Neeraj
- Bhandari Bharti Bhandari
- Bhardwaj Nikha
- Bhardwaj Pankaj
- Bhattacharyya Krittika
- Bhojaraja Vijayalakshmi S
- Bhuyan Soumitra S
- Bibi Sadia
- Bicer Burcu Kucuk
- Bilchut Awraris Hailu
- Bintoro Bagas Suryo
- Biondi Antonio
- Birega Mesfin Geremaw Birega
- Birhan Habitu Eshetu
- Bjørge Tone
- Blyuss Oleg
- Bodicha Belay Boda Abule
- Bohan Phillip M Kemp
- Bolla Srinivasa Rao
- Boloor Archith
- Bosetti Cristina
- Braithwaite Dejana
- Brauer Michael
- Brenner Hermann
- Briko Andrey Nikolaevich
- Briko Nikolay Ivanovich
- Buchanan Christina Maree
- Bulamu Norma B
- Bustamante-Teixeira Maria Teresa
- Butt Muhammad Hammad
- Butt Nadeem Shafique
- Butt Zahid A
- Cao Chao
- Cao Yin
- Carreras Giulia
- Carvalho Márcia
- Cembranel Francieli
- Cerin Ester
- Chakraborty Promit Ananyo
- Chandrasekar Viveksandeep Thoguluva
- Charalampous Periklis
- Chattu Vijay Kumar
- Chimed-Ochir Odgerel
- Chirinos-Caceres Jesus Lorenzo
- Cho Daniel Youngwhan
- Cho William CS
- Christopher Devasahayam J
- Chu Dinh-Toi
- Chukwu Isaac Sunday
- Cohen Aaron J
- Collaborators GBD 2019 Cancer Risk Factors
- Compton Kelly
- Conde Joao
- Cortés Sandra
- Costa Vera Marisa
- Cruz-Martins Natália
- Culbreth Garland T
- Cámera Luis Alberto
- Dadras Omid
- Dagnaw Fentaw Teshome
- Dahlawi Saad MA
- Dai Xiaochen
- Dandona Lalit
- Dandona Rakhi
- Daneshpajouhnejad Parnaz
- Danielewicz Anna
- Dao An Thi Minh
- Darwesh Aso Mohammad
- Das Saswati
- Davitoiu Dragos Virgil
- De la Hoz Fernando Pio
- Debela Sisay Abebe
- Dehghan Azizallah
- Dehkordi Javad Javad Aminian
- Demisse Biniyam
- Demisse Fitsum Wolde
- Denova-Gutiérrez Edgar
- Derakhshani Afshin
- Dereje Diriba
- Deribe Kalkidan Solomon
- Desai Rupak
- Desalegn Markos Desalegn
- Desideri Lorenzo Ferro
- Dessalegn Fikadu Nugusu
- Dessalegni Samuel Abebe A
- Dessie Gashaw
- Desta Abebaw Alemayehu
- Dewan Syed Masudur Rahman
- Dharmaratne Samath Dhamminda
- Dhimal Meghnath
- Dianatinasab Mostafa
- Diao Nancy
- Diaz Daniel
- Digesa Lankamo Ena
- Dixit Shilpi Gupta
- Doaei Saeid
- Doan Linh Phuong
- Doku Paul Narh
- Dongarwar Deepa
- dos Santos Florentino Luciano Caetano
- dos Santos Wendel Mombaque
- Driscoll Tim Robert
- Dsouza Haneil Larson
- Durojaiye Oyewole Christopher
- Edalati Sareh
- Eghbalian Fatemeh
- Ehsani-Chimeh Elham
- Eini Ebrahim
- Ekholuenetale Michael
- Ekundayo Temitope Cyrus
- Ekwueme Donatus U
- El-Huneidi Waseem
- Elbahnasawy Mostafa Ahmed
- Elbarazi Iffat
- Elghazaly Hesham
- Elhadi Muhammed
- Emamian Mohammad Hassan
- Enyew Daniel Berhanie
- Erkhembayar Ryenchindorj
- Eshetu Tegegne
- Eshrati Babak
- Eskandarieh Sharareh
- Esmaeili Elham Davtalab
- Espinosa-Montero Juan
- Etaee Farshid
- Etemadimanesh Azin
- Eyayu Tahir
- Ezeonwumelu Ifeanyi Jude
- Ezzikouri Sayeh
- Fagbamigbe Adeniyi Francis
- Fahimi Saman
- Fakhradiyev Ildar Ravisovich
- Faraon Emerito Jose A
- Fares Jawad
- Farmany Abbas
- Farooque Umar
- Farrokhpour Hossein
- Fasanmi Abidemi Omolara
- Fatehizadeh Ali
- Fatima Wafa
- Fattahi Hamed
- Fekadu Ginenus
- Feleke Berhanu Elfu
- Ferrari Allegra Allegra
- Ferrero Simone
- Filip Irina
- Fischer Florian
- Fonseca Mariana Gaspar
- Force Lisa M
- Foroumadi Roham
- Foroutan Masoud
- Fukumoto Takeshi
- Gaal Peter Andras
- Gad Mohamed M
- Gadanya Muktar A
- Gaipov Abduzhappar
- Galehdar Nasrin
- Gallus Silvano
- Garg Tushar
- Gebremariam Yosef Haile
- Gebremeskel Teferi Gebru
- Gebremichael Mathewos Alemu
- Geda Yohannes Fikadu
- Gela Yibeltal Yismaw
- Gemeda Belete Negese Belete
- Getachew Melaku
- Getachew Motuma Erena
- Ghaffari Kazem
- Ghafourifard Mansour
- Ghamari Seyyed-Hadi
- Ghassemi Fariba
- Ghimire Ajnish
- Ghith Nermin
- Gholamalizadeh Maryam
- Ghozy Sherief
- Gilani Syed Amir
- Gill Paramjit Singh
- Ginindza Themba G
- Gizaw Abraham Tamirat T
- Glasbey James C
- Godos Justyna
- Goel Amit
- Golechha Mahaveer
- Goleij Pouya
- Golinelli Davide
- Golitaleb Mohamad
- Gorini Giuseppe
- Goulart Bárbara Niegia Garcia
- Grosso Giuseppe
- Guadie Habtamu Alganeh
- Gubari Mohammed Ibrahim Mohialdeen
- Gudayu Temesgen Worku
- Guerra Maximiliano Ribeiro
- Gunawardane Damitha Asanga
- Gupta Bhawna
- Gupta Sapna
- Gupta Veer Bala
- Gupta Vivek Kumar
- Gurara Mekdes Kondale
- Guta Alemu
- Habibzadeh Parham
- Hafezi-Nejad Nima
- Haj-Mirzaian Arvin
- Halboub Esam S
- Halimi Aram
- Halwani Rabih
- Hamad Hanadi Al
- Hamadeh Randah R
- Hameed Sajid
- Hamidi Samer
- Hanif Asif
- Hariri Sanam
- Harlianto Netanja I
- Haro Josep Maria
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- Hasaballah Ahmed I
- Hasan SM Mahmudul
- Hasani Hamidreza
- Hashemi Seyedeh Melika
- Hassan Abbas M
- Hassanipour Soheil
- Hay Simon I
- Hayat Khezar
- Heidari Golnaz
- Heidari Mohammad
- Heidarymeybodi Zahra
- Henrikson Hannah Jacqueline
- Herrera-Serna Brenda Yuliana
- Herteliu Claudiu
- Hezam Kamal
- Hiraike Yuta
- Hlongwa Mbuzeleni Mbuzeleni
- Holla Ramesh
- Holm Marianne
- Horita Nobuyuki
- Hoseini Mohammad
- Hossain Mahbub
- Hossain Mohammad Bellal Hossain
- Hosseini Mohammad-Salar
- Hosseinzadeh Ali
- Hosseinzadeh Mehdi
- Hostiuc Mihaela
- Hostiuc Sorin
- Househ Mowafa
- Huang Junjie
- Hugo Fernando N
- Humayun Ayesha
- Hussain Salman
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- Immurana Mustapha
- Innos Kaire
- Iranpour Pooya
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- Islam Shariful
- Islami Farhad
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- Iwagami Masao
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- Jafari Amirhossein Azari
- Jaiswal Abhishek
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- Jang Sung-In
- Jani Chinmay T
- Javaheri Tahereh
- Jayarajah Umesh Umesh
- Jayaram Shubha
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- Jonas Jost B
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- Joo Tamas
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- Kandaswamy Eswar
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- Kebede Abinet Gebremickael
- Keikavoosi-Arani Leila
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- Keramati Maryam
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- Khaneghah Amin Mousavi
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- Mir Shabir Ahmad
- Mirinezhad Seyed Kazem
- Mirmoeeni Seyyedmohammadsadeq
- Mirza-Aghazadeh-Attari Mohammad
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- Misra Sanjeev
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- Mostafavi Ebrahim
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- Prashant Akila
- Qadir Mirza Muhammad Fahd
- Quintanilla Beatriz Paulina Ayala
- Rabiee Mohammad
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- Rad Elaheh Malakan
- Radfar Amir
- Radhakrishnan Raghu Anekal
- Radhakrishnan Venkatraman
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- Safary Azam
- Sahebazzamani Maryam
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- Shirkoohi Reza
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- Shivarov Velizar
- Shobeiri Parnian
- Shorofi Seyed Afshin
- Shrestha Sunil
- Sibhat Migbar Mekonnen
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- Silvestris Nicola
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- Soltani-Zangbar Mohammad Sadegh
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- Song Yimeng
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- Sorensen Reed JD
- Soshnikov Sergey
- Sotoudeh Houman
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- Sur Daniel
- Swamy Sreenivas Narasimha
- Syed Zahiruddin Quazi
- Szócska Miklós
- Tabaeian Seidamir Pasha
- Tabari Mohammad Amin Khazeei
- Tabarés-Seisdedos Rafael
- Tabatabaei Seyyed Mohammad
- Tabuchi Takahiro
- Tadbiri Hooman
- Tahbaz Sahel Valadan
- Taheri Ensiyeh
- Taheri Majid
- Takahashi Ken
- Talaat Iman M
- Tampa Mircea
- Tan Ker-Kan
- Tantawi Maha El
- Tat Nathan Y
- Tat Vivian Y
- Tavakoli Ahmad
- Tavakoli Arash
- Tehrani-Banihashemi Arash
- Tekalegn Yohannes
- Tesfay Fisaha Haile
- Thapar Rekha
- Thavamani Aravind
- Thomas Nihal
- Thomas Nikhil Kenny
- Ticoalu Jansje Henny Vera
- Tiyuri Amir
- Tollosa Daniel Nigusse
- Topor-Madry Roman
- Toroudi Hamidreza Pazoki
- Touvier Mathilde
- Tovani-Palone Marcos Roberto
- Traini Eugenio
- Tran Khanh Bao
- Tran Mai Thi Ngoc
- Tripathy Jaya Prasad
- Ukke Gebresilasea Gendisha
- Ullah Irfan
- Ullah Saif
- Ullah Sana
- Unnikrishnan Bhaskaran
- Vacante Marco
- Vaezi Maryam
- Valdez Pascual R
- Van Nguyen Nguyen Huy
- Vardavas Constantine
- Varniab Zahra Shokri
- Varthya Shoban Babu
- Vaziri Siavash
- Velazquez Diana Zuleika
- Veroux Massimiliano
- Villeneuve Paul J
- Violante Francesco S
- Vladimirov Sergey Konstantinovitch
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- Vos Theo
- Vu Linh Gia
- Wadood Abdul Wadood
- Waheed Yasir
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- Wamai Richard G
- Wang Cong
- Wang Fang
- Wang Ning
- Wang Yu
- Ward Paul
- Waris Abdul
- Westerman Ronny
- Wickramasinghe Nuwan Darshana
- Woldemariam Melat
- Woldu Berhanu
- Xiao Hong
- Xu Rixing
- Xu Suowen
- Xu Xiaoyue
- Yadav Lalit
- Yang Lin
- Yazdanpanah Fereshteh
- Yeshaw Yigizie
- Yismaw Yazachew
- Yonemoto Naohiro
- Younis Mustafa Z
- Yousefi Zabihollah
- Yousefian Fatemeh
- Yu Chuanhua
- Yu Yong
- Yunusa Ismaeel
- Zahir Mazyar
- Zaki Nazar
- Zaman Burhan Abdullah
- Zangiabadian Moein
- Zare Fariba
- Zare Iman
- Zareshahrabadi Zahra
- Zarrintan Armin
- Zastrozhin Mikhail Sergeevich
- Zeineddine Mohammad A
- Zhang Dongyu
- Zhang Jianrong
- Zhang Yunquan
- Zhang Zhi-Jiang
- Zhou Linghui
- Zodpey Sanjay
- Zoladl Mohammad
- Šekerija Mario
- Publication venue
- Publication date
- 01/01/2022
- Field of study
Background Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. Methods The GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk-outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 2019 and change in these measures between 2010 and 2019 are presented. Findings Globally, in 2019, the risk factors included in this analysis accounted for 4.45 million (95% uncertainty interval 4.01-4.94) deaths and 105 million (95.0-116) DALYs for both sexes combined, representing 44.4% (41.3-48.4) of all cancer deaths and 42.0% (39.1-45.6) of all DALYs. There were 2.88 million (2.60-3.18) risk-attributable cancer deaths in males (50.6% [47.8-54.1] of all male cancer deaths) and 1.58 million (1.36-1.84) risk-attributable cancer deaths in females (36.3% [32.5-41.3] of all female cancer deaths). The leading risk factors at the most detailed level globally for risk-attributable cancer deaths and DALYs in 2019 for both sexes combined were smoking, followed by alcohol use and high BMI. Risk-attributable cancer burden varied by world region and Socio-demographic Index (SDI), with smoking, unsafe sex, and alcohol use being the three leading risk factors for risk-attributable cancer DALYs in low SDI locations in 2019, whereas DALYs in high SDI locations mirrored the top three global risk factor rankings. From 2010 to 2019, global risk-attributable cancer deaths increased by 20.4% (12.6-28.4) and DALYs by 16.8% (8.8-25.0), with the greatest percentage increase in metabolic risks (34.7% [27.9-42.8] and 33.3% [25.8-42.0]). Interpretation The leading risk factors contributing to global cancer burden in 2019 were behavioural, whereas metabolic risk factors saw the largest increases between 2010 and 2019. Reducing exposure to these modifiable risk factors would decrease cancer mortality and DALY rates worldwide, and policies should be tailored appropriately to local cancer risk factor burden. Copyright (C) 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.Peer reviewe
Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
- Author
- Aali Amirali
- Abbafati Cristiana
- Abbas Jaffar
- Abbasgholizadeh Rouzbeh
- Abbasi Madineh Akram
- Abbasian Mohammadreza
- Abd ElHafeez Samar
- Abd-Elsalam Sherief
- Abdelmasseh Michael
- Abdelwahab Ahmed
- Abdollahi Mohammad
- Abdoun Meriem
- Abdullahi Auwal
- Abdurehman Ame Mehadi
- Abebe Mesfin
- Abedi Aidin
- Abedi Armita
- Abegaz Tadesse M
- Abeldaño Zuñiga Roberto Ariel
- Abhilash E S
- Abiodun Olugbenga Olusola
- Aboagye Richard Gyan
- Abolhassani Hassan
- Abouzid Mohamed
- Abreu Lucas Guimarães
- Abrha Woldu Aberhe
- Abrigo Michael R M
- Abtahi Dariush
- Abu Rumeileh Samir
- Abu-Rmeileh Niveen ME
- Abu-Zaid Ahmed
- Aburuz Salahdein
- Acuna Juan Manuel
- Adair Tim
- Addo Isaac Yeboah
- Adebayo Oladimeji M
- Adegboye Oyelola A
- Adekanmbi Victor
- Aden Bashir
- Adepoju Abiola Victor
- Adetunji Charles Oluwaseun
- Adeyeoluwa Temitayo Esther
- Adeyomoye Olorunsola Israel
- Adha Rishan
- Adibi Amin
- Adikusuma Wirawan
- Adnani Qorinah Estiningtyas Sakilah
- Adra Saryia
- Afework Abel
- Afolabi Aanuoluwapo Adeyimika
- Afraz Ali
- Afyouni Shadi
- Afzal Saira
- Agasthi Pradyumna
- Aghamiri Shahin
- Agodi Antonella
- Agyemang-Duah Williams
- Ahinkorah Bright Opoku
- Ahmad Aqeel
- Ahmad Danish
- Ahmad Firdos
- Ahmad Muayyad M
- Ahmad Tauseef
- Ahmadi Keivan
- Ahmadzade Amir Mahmoud
- Ahmadzade Mohadese
- Ahmed Ayman
- Ahmed Haroon
- Ahmed Luai A
- Ahmed Muktar Beshir
- Ahmed Syed Anees
- Ajami Marjan
- Aji Budi
- Ajumobi Olufemi
- Akalu Gizachew Taddesse
- Akara Essona Matatom
- Akinosoglou Karolina
- Akkala Sreelatha
- Akyirem Samuel
- Al Hamad Hanadi
- Al Hasan Syed Mahfuz
- Al Homsi Ammar
- Al Qadire Mohammad
- AL-Ahdal Tareq Mohammed Ali
- Al-Aly Ziyad
- Al-amer Rasmieh Mustafa
- Al-Eyadhy Ayman
- Al-Gheethi Adel Ali Saeed
- Al-Hanawi Mohammed Khaled
- Al-Jumaily Adel
- Al-Marwani Sabah
- Al-Maweri Sadeq Ali Ali
- Al-Mekhlafi Hesham M
- Al-Sabah Salman Khalifah
- Al-Tawfiq Jaffar A
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- Alhabib Khalid F
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- Ali Abid
- Ali Akhtar
- Ali Beriwan Abdulqadir
- Ali Hassam
- Ali Mohammed Usman
- Ali Rafat
- Ali Syed Shujait Shujait
- Ali Zahid
- Alian Samakkhah Shohreh
- Alicandro Gianfranco
- Alif Sheikh Mohammad
- Aligol Mohammad
- Alimi Rasoul
- Aliyi Ahmednur Adem
- Aljunid Syed Mohamed
- Almahmeed Wael
- Almazan Joseph Uy
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- Alomari Mahmoud A
- Alonso Nivaldo
- Alqahtani Jaber S
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- Amzat Jimoh
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- Bleyer Archie
- Boampong Mary Sefa
- Bodolica Virginia
- Bodunrin Aadam Olalekan
- Bolarinwa Obasanjo Afolabi
- Bonakdar Hashemi Milad
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- Bora Basara Berrak
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- Chang Chin-Kuo
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- Chavula Malizgani Paul
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- De Leo Diego
- Debele Aklilu Tamire
- Degenhardt Louisa
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- Dolecek Christiane
- Dorsey E Ray
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- Fahimi Saman
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- Faris MoezAlIslam Ezzat Mahmoud
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- Samadi Kafil Hossein
- Samadzadeh Sara
- Samara Kamel A
- Samargandy Saad
- Samodra Yoseph Leonardo
- Samuel Vijaya Paul
- Samy Abdallah M
- Sanabria Juan
- Sanadgol Nima
- Sanganyado Edmond
- Sanjeev Rama Krishna
- Sanmarchi Francesco
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- Sarasmita Made Ary
- Saravanan Aswini
- Saravi Babak
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- Sarveazad Arash
- Sathian Brijesh
- Sathish Thirunavukkarasu
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- Saxena Sonia
- Saya Ganesh Kumar
- Sayadi Yaser
- Sayeed Abu
- Sayeed Md Abu
- Saylan Mete
- Scarmeas Nikolaos
- Schaarschmidt Benedikt Michael
- Schlee Winfried
- Schmidt Maria Inês
- Schuermans Art
- Schumacher Austin E
- Schwebel David C
- Schwendicke Falk
- Selvaraj Siddharthan
- Semreen Mohammad H
- Senapati Sabyasachi
- Sengupta Pallav
- Senthilkumaran Subramanian
- Sepanlou Sadaf G
- Serban Dragos
- Sertsu Addisu
- Sethi Yashendra
- SeyedAlinaghi SeyedAhmad
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- Shafaat Amir
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- Shafiee Arman
- Shah Nilay S
- Shah Pritik A
- Shahabi Saeed
- Shahbandi Ataollah
- Shahid Izza
- Shahid Samiah
- Shahid Wajeehah
- Shahwan Moyad Jamal
- Shaikh Masood Ali
- Shakeri Alireza
- Shakil Husain
- Sham Sunder
- Shamim Muhammad Aaqib
- Shams-Beyranvand Mehran
- Shamshad Hina
- Shamshirgaran Mohammad Ali
- Shamsi Mohammad Anas
- Shanawaz Mohd
- Shankar Abhishek
- Sharfaei Sadaf
- Sharifan Amin
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- Sharma Manoj
- Sharma Rajesh
- Sharma Saurab
- Sharma Vishal
- Shastry Rajesh P
- Shavandi Amin
- Shaw David H
- Shayan Amir Mehdi
- Shehabeldine Amr Mohamed Elsayed
- Sheikh Aziz
- Sheikhi Rahim Ali
- Shen Jiabin
- Shenoy Manjunath Mala
- Shetty B Suresh Kumar
- Shetty Ranjitha S
- Shey Robert Adamu
- Shiani Amir
- Shibuya Kenji
- Shiferaw Desalegn
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- Shin Jae Il
- Shin Min-Jeong
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- Shittu Aminu
- Shiue Ivy
- Shivakumar K M
- Shivarov Velizar
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- Shuval Kerem
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- Singh Ambrish
- Singh Balbir Bagicha
- Singh Baljinder
- Singh Mahendra
- Singh Mayank
- Singh Narinder Pal
- Singh Paramdeep
- Singh Surjit
- Siraj Md Shahjahan
- Sitas Freddy
- Sivakumar Shravan
- Skryabin Valentin Yurievich
- Skryabina Anna Aleksandrovna
- Sleet David A
- Slepak Erica Leigh N
- Sohrabi Hanye
- Soleimani Hamidreza
- Soliman Sameh S M
- Solmi Marco
- Solomon Yonatan
- Song Yimeng
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- Soriano Joan B
- Soyiri Ireneous N
- Spartalis Michael
- Sreeramareddy Chandrashekhar T
- Starnes Joseph R
- Starodubov Vladimir I
- Starodubova Antonina V
- Stefan Simona Cătălina
- Stein Dan J
- Steinbeis Fridolin
- Steiropoulos Paschalis
- Stockfelt Leo
- Stokes Mark A
- Stortecky Stefan
- Stranges Saverio
- Stroumpoulis Konstantinos
- Suleman Muhammad
- Suliankatchi Abdulkader Rizwan
- Sultana Abida
- Sun Jing
- Sunkersing David
- Susanty Sri
- Swain Chandan Kumar
- Sykes Bryan L
- Szarpak Lukasz
- Szeto Mindy D
- Szócska Miklós
- Šekerija Mario
- Tabaee Damavandi Payam
- Tabatabaei Malazy Ozra
- Tabatabaeizadeh Seyed-Amir
- Tabatabai Shima
- Tabb Karen M
- Tabish Mohammad
- Taborda-Barata Luis M
- Tabuchi Takahiro
- Tadesse Birkneh Tilahun
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- Taheri Soodejani Moslem
- Taheri Amirmasoud
- Taherkhani Amir
- Taiba Jabeen
- Tajbakhsh Ardeshir
- Talaat Iman M
- Talukder Ashis
- Tamuzi Jacques Lukenze
- Tan Ker-Kan
- Tang Haosu
- Tang Hong K
- Tat Nathan Y
- Tat Vivian Y
- Tavakoli Oliaee Razieh
- Tavangar Seyed Mohammad
- Taveira Nuno
- Tebeje Tsion Mulat
- Tefera Yibekal Manaye
- Teimoori Mojtaba
- Temsah Mohamad-Hani
- Temsah Reem Mohamad Hani
- Teramoto Masayuki
- Tesfaye Solomon Hailemariam
- Thangaraju Pugazhenthan
- Thankappan Kavumpurathu Raman
- Thapa Rajshree
- Thapar Rekha
- Thomas Nihal
- Thrift Amanda G
- Thum Chern Choong Chern
- Tian Jing
- Tichopad Ales
- Ticoalu Jansje Henny Vera
- Tiruye Tenaw Yimer
- Tohidast Seyed Abolfazl
- Tonelli Marcello
- Touvier Mathilde
- Tovani-Palone Marcos Roberto
- Tram Khai Hoan
- Tran Nghia Minh
- Trico Domenico
- Trihandini Indang
- Tromans Samuel Joseph
- Truong Vien T
- Truyen Thien Tan Tri Tai
- Tsermpini Evangelia Eirini
- Tumurkhuu Munkhtuya
- Tung Kang
- Tyrovolas Stefanos
- Ubah Chukwudi S
- Udoakang Aniefiok John
- Udoh Arit
- Ulhaq Inam
- Ullah Saeed
- Ullah Sana
- Umair Muhammad
- Umar Tungki Pratama
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- Umesh Anushri
- Unim Brigid
- Unnikrishnan Bhaskaran
- Upadhyay Era
- Urso Daniele
- Vacante Marco
- Vahdani Amir Mohammad
- Vaithinathan Asokan Govindaraj
- Valadan Tahbaz Sahel
- Valizadeh Rohollah
- Van den Eynde Jef
- Varavikova Elena
- Varga Orsolya
- Varma Siddhartha Alluri
- Vart Priya
- Varthya Shoban Babu
- Vasankari Tommi Juhani
- Veerman Lennert J
- Venketasubramanian Narayanaswamy
- Venugopal Deneshkumar
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- Verma Madhur
- Verma Pratibha
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- Verras Georgios-Ioannis
- Vervoort Dominique
- Vieira Rafael José
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- Villani Leonardo
- Villanueva Gabriela Ines
- Villeneuve Paul J
- Violante Francesco S
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- Volovici Victor
- Vongpradith Avina
- Vos Theo
- Vujcic Isidora S
- Vukovic Rade
- Wado Yohannes Dibaba
- Wafa Hatem A
- Waheed Yasir
- Wamai Richard G
- Wang Cong
- Wang Denny
- Wang Fang
- Wang Shu
- Wang Song
- Wang Yanzhong
- Wang Yuan-Pang
- Ward Paul
- Watson Stefanie
- Weaver Marcia R
- Weerakoon Kosala Gayan
- Weiss Daniel J
- Weldemariam Abrha Hailay
- Wells Katherine M
- Wen Yi Feng
- Werdecker Andrea
- Westerman Ronny
- Wickramasinghe Dakshitha Praneeth
- Wickramasinghe Nuwan Darshana
- Wijeratne Tissa
- Wilson Shadrach
- Wojewodzic Marcin W
- Wool Eve E
- Woolf Anthony D
- Wu Dongze
- Wulandari Ratna Dwi
- Xiao Hong
- Xu Bin
- Xu Xiaoyue
- Yadav Lalit
- Yaghoubi Sajad
- Yang Lin
- Yano Yuichiro
- Yao Yao
- Ye Pengpeng
- Yesera Gesila Endashaw
- Yesodharan Renjulal
- Yesuf Subah Abderehim
- Yiğit Arzu
- Yiğit Vahit
- Yip Paul
- Yon Dong Keon
- Yonemoto Naohiro
- You Yuyi
- Younis Mustafa Z
- Yu Chuanhua
- Zadey Siddhesh
- Zadnik Vesna
- Zafari Nima
- Zahedi Mohammad
- Zahid Muhammad Nauman
- Zahir Mazyar
- Zakham Fathiah
- Zaki Nazar
- Zakzuk Josefina
- Zamagni Giulia
- Zaman Burhan Abdullah
- Zaman Sojib Bin
- Zamora Nelson
- Zand Ramin
- Zandi Milad
- Zandieh Ghazal G Z
- Zanghì Aurora
- Zare Iman
- Zastrozhin Mikhail Sergeevich
- Zeariya Mohammed G M
- Zeng Youjie
- Zhai Chunxia
- Zhang Chen
- Zhang Haijun
- Zhang Hongwei
- Zhang Yunquan
- Zhang Zhaofeng
- Zhang Zhenyu
- Zhao Hanqing
- Zhao Yang
- Zhao Yong
- Zheng Peng
- Zhong Chenwen
- Zhou Juexiao
- Zhu Bin
- Zhu Zhaohua
- Ziaeefar Pardis
- Zielińska Magdalena
- Zou Zhiyong
- Zumla Alimuddin
- Zweck Elric
- Zyoud Samer H
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Background: Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this unprecedented event within the context of long-term population health trends. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 provides new demographic estimates for 204 countries and territories and 811 additional subnational locations from 1950 to 2021, with a particular emphasis on changes in mortality and life expectancy that occurred during the 2020–21 COVID-19 pandemic period. Methods: 22 223 data sources from vital registration, sample registration, surveys, censuses, and other sources were used to estimate mortality, with a subset of these sources used exclusively to estimate excess mortality due to the COVID-19 pandemic. 2026 data sources were used for population estimation. Additional sources were used to estimate migration; the effects of the HIV epidemic; and demographic discontinuities due to conflicts, famines, natural disasters, and pandemics, which are used as inputs for estimating mortality and population. Spatiotemporal Gaussian process regression (ST-GPR) was used to generate under-5 mortality rates, which synthesised 30 763 location-years of vital registration and sample registration data, 1365 surveys and censuses, and 80 other sources. ST-GPR was also used to estimate adult mortality (between ages 15 and 59 years) based on information from 31 642 location-years of vital registration and sample registration data, 355 surveys and censuses, and 24 other sources. Estimates of child and adult mortality rates were then used to generate life tables with a relational model life table system. For countries with large HIV epidemics, life tables were adjusted using independent estimates of HIV-specific mortality generated via an epidemiological analysis of HIV prevalence surveys, antenatal clinic serosurveillance, and other data sources. Excess mortality due to the COVID-19 pandemic in 2020 and 2021 was determined by subtracting observed all-cause mortality (adjusted for late registration and mortality anomalies) from the mortality expected in the absence of the pandemic. Expected mortality was calculated based on historical trends using an ensemble of models. In location-years where all-cause mortality data were unavailable, we estimated excess mortality rates using a regression model with covariates pertaining to the pandemic. Population size was computed using a Bayesian hierarchical cohort component model. Life expectancy was calculated using age-specific mortality rates and standard demographic methods. Uncertainty intervals (UIs) were calculated for every metric using the 25th and 975th ordered values from a 1000-draw posterior distribution. Findings: Global all-cause mortality followed two distinct patterns over the study period: age-standardised mortality rates declined between 1950 and 2019 (a 62·8% [95% UI 60·5–65·1] decline), and increased during the COVID-19 pandemic period (2020–21; 5·1% [0·9–9·6] increase). In contrast with the overall reverse in mortality trends during the pandemic period, child mortality continued to decline, with 4·66 million (3·98–5·50) global deaths in children younger than 5 years in 2021 compared with 5·21 million (4·50–6·01) in 2019. An estimated 131 million (126–137) people died globally from all causes in 2020 and 2021 combined, of which 15·9 million (14·7–17·2) were due to the COVID-19 pandemic (measured by excess mortality, which includes deaths directly due to SARS-CoV-2 infection and those indirectly due to other social, economic, or behavioural changes associated with the pandemic). Excess mortality rates exceeded 150 deaths per 100 000 population during at least one year of the pandemic in 80 countries and territories, whereas 20 nations had a negative excess mortality rate in 2020 or 2021, indicating that all-cause mortality in these countries was lower during the pandemic than expected based on historical trends. Between 1950 and 2021, global life expectancy at birth increased by 22·7 years (20·8–24·8), from 49·0 years (46·7–51·3) to 71·7 years (70·9–72·5). Global life expectancy at birth declined by 1·6 years (1·0–2·2) between 2019 and 2021, reversing historical trends. An increase in life expectancy was only observed in 32 (15·7%) of 204 countries and territories between 2019 and 2021. The global population reached 7·89 billion (7·67–8·13) people in 2021, by which time 56 of 204 countries and territories had peaked and subsequently populations have declined. The largest proportion of population growth between 2020 and 2021 was in sub-Saharan Africa (39·5% [28·4–52·7]) and south Asia (26·3% [9·0–44·7]). From 2000 to 2021, the ratio of the population aged 65 years and older to the population aged younger than 15 years increased in 188 (92·2%) of 204 nations. Interpretation: Global adult mortality rates markedly increased during the COVID-19 pandemic in 2020 and 2021, reversing past decreasing trends, while child mortality rates continued to decline, albeit more slowly than in earlier years. Although COVID-19 had a substantial impact on many demographic indicators during the first 2 years of the pandemic, overall global health progress over the 72 years evaluated has been profound, with considerable improvements in mortality and life expectancy. Additionally, we observed a deceleration of global population growth since 2017, despite steady or increasing growth in lower-income countries, combined with a continued global shift of population age structures towards older ages. These demographic changes will likely present future challenges to health systems, economies, and societies. The comprehensive demographic estimates reported here will enable researchers, policy makers, health practitioners, and other key stakeholders to better understand and address the profound changes that have occurred in the global health landscape following the first 2 years of the COVID-19 pandemic, and longer-term trends beyond the pandemic
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- Abdala Antonio
- Abidi Khalid
- Abillama Fayez François
- Abos Francisco Javier Saenz
- Aboufray Ahmed Ali
- Abregal Giancarlo
- Abroug Fekri
- Achilleos Eleni
- Acosta Ysica
- Adam Višnja Nesek
- Adamina Ileana
- Adams John
- Adamuz Jordi
- Adejumo Prisca Olabisi
- Adekola Oyebola
- Ademokun Jane
- Adenekan Anthony
- Adib Nik Azman Nik
- Adipa Faustina Excel
- Afonso Elsa
- Aganon Ferdinand
- Agarwal Sonika
- Aguirre Joaquin
- Aguirre Lydia Gallego
- Aguirre-Bermeo Hernan
- Ahmad Fatima Kasem El
- Ahmad Meraj
- Ahmed Hazem
- Ahn Jong-Joon
- Ahtiala Maarit
- Akbas Turkay
- Akdağ Devrim
- Akker Mustafa
- Akselsen Gro Ringstad
- Al-Alawi Maram Milud Said
- Alabuzidi Aya
- Alampi Daniela
- Albaiceta Guillermo Muñiz
- Albert Patricia
- Albrecht Lea
- Albrett Jonathan
- Alexandropoulou Paraskevi
- Alexandrou Anna
- Ali Ashwaq
- Ali Mohd Nazri
- Alias Anita
- Alkhumsi Soad Imhmed R.
- Allaert Silvie
- Allison Nicola
- Almekhlafi Ghaleb
- Alonso Helena Fernandez
- Alsheikhly Ahmed Subhy
- Alshrif Abdualhamid I
- Alvarenga Gloria
- Alvarez Diana
- Alvarez Gonzalo Martín
- Alvarez Gustavo Andres
- Alvarez Jorge Duerto
- Alvarez Josep Trenado
- Alvarez Raquel Garcia
- Alves Paulo
- Andersen Marit Hildegunn
- Andersen Yvonne
- Andresen Hanne
- Anisoglou Souzana
- Antonio Maria Gracia San
- Antunes Nelson
- Anvelt Eneli
- Aperocho Cristal April Jane
- Aponte Cesar
- Araya Paola
- Arcas María Luisa Bravo
- Arikan Huseyin
- Arntsen Wenche
- Arteta Arteta Donaldo S.
- Ashour Firas
- Assiri Amer
- Atchade Enora
- Ateya Zainab
- Attwood Ben
- Aucapina Alejandra
- Avalos Fernando
- Aves Emma
- Avogadro Prune
- Avramopoulou Lamprini
- Ay Mustafa
- Ay Serap Avcı
- Aya Umeda
- Ayala Maria
- Aydemir Semih
- Aydin Demet Tok
- Azencot Mazal
- Azoia Joao
- Baasanjav Battsetseg
- Babych Volodymyr
- Baccaro Fernando
- Badariotti Gustavo
- Bae Jung-Min
- Baek Jonghyun
- Baftiu Nehat
- Bagshaw Sean
- Bahrin Laila Kamaliah Kamalul
- Bai Dongmei
- Bai Xiaowu
- Baini Matías
- Bakas Apostolos
- Baker Helen
- Baker Nerilee
- Balasubramanian Madhu
- Balbay Abidin Oner
- Balon Sandrine
- Bantar Ana
- Banwarie Preveen
- Bao Guijun
- Baptiste-Savoie Jacqueline
- Barakat-Johnson Michelle
- Barefield Cindy
- Barkas Diane
- Barnes Christopher
- Barone Antonio
- Baronia Arvind
- Barr Louise
- Barreiro Emma Moreno
- Barros Elaine
- Barrowcliffe Suzanne
- Barrueco-Francioni Jesus Emilio
- Bartoli Julio Ricardo
- Baruah Rosaleen
- Bascary Carlos Alejandro
- Baskakov Danil
- Baskoro Windu
- Bastani Styliani
- Baumber Rachel
- Baxter Karen
- Bayraktar Yesim Serife
- Bealer Cheryl
- Bean Sarah
- Becker Cathy
- Becker Delmiro
- Behan Helena
- Beker Tatjana
- Bekos Vasileios
- Belii Adrian
- Belkhair Wesal Ali
- Belskiy Vladislav
- Ben-Hamouda Nawfel
- Ben-Jacob Talia
- Benbenishty Julie
- Bench Suzanne
- Bendelari Valentina
- Benlamin Mohamed
- Berry Gillian
- Bertoletti Fernando Pablo
- Besbes Lamia
- Besbes Lamia Ouanes
- Besch Guillaume
- Bestle Morten
- Beuret Pascal
- Bhakhtiani Lakshay
- Bhargava Vaibhav
- Bi AiPing
- Bianchini Suzana
- Bielskute Egidija
- Bilawicz Jan
- Binda Filipo
- Birgisdottir Hrönn
- Birgisdóttir Hrönn
- Bispo Bruno Miguel
- Biston Patrick
- Bjorgen Hege
- Blackwood Bronagh
- Blanc Agnès
- Blanco Daniel
- Blanco Maria Pilar Sogues
- Blasco Maria Luisa
- Bliksted Inger Abildgaard
- Blondal Asbjorn
- Bloos Frank
- Blot Stijn I.
- Bo Qi
- Bocui Nie
- Boedjawan Naraindath N.
- Bogarin Javier
- Bogoevska-Miteva Zaneta
- Bonaccorso Luciano
- Bongiorno Benjamin
- Bonsignore Pablo Julio Maldonaldo
- Borgognoni Cinzia
- Borin Christophe
- Borkowska Marta
- Bormans Laura
- Boroli Filippo
- Borys Michal
- Boschetto Margherita
- Bossolasco Matteo
- Bota Marc
- Boulanger Carole
- Boulton Karen
- Bowes Bonnie
- Boyer Laetitia
- Bozbay Suha
- Bozena Armanda
- Bratsberg Bjorn
- Bravo Silvina
- Brett Carole
- Brett Stephen
- Brett Stephen J.
- Briva Arturo
- Brizio Elisabetta
- Brizuela Patricia
- Broadhurst Phil
- Brown Wendy
- Browne Troy
- Bruel Cédric
- Bruhn Louise
- Brumwell Sarah
- Bruni Andrea
- Bruno Anna Vita
- Buckley Sarah
- Bull Rhian
- Bumbasirevic Vesna
- Buregeya Egide
- Burns Karen
- Butcher Rand
- Byers Heather
- Bösl Kathrin
- Cabral Dolly Mabel Bordon
- Cabral João
- Cabrita Paula
- Caddell Paul
- Caicedo Nestor
- Calamai Italo
- Calili Duygu Kayar
- Caliskan Gulbahar
- Calleja Pablo Lopez-Arcas
- Calpe Neus
- Calvino-Gunther Silvia
- Campanili Ticiane
- Campbell Elizabeth
- Campos Pierina Arias
- Campos-Perez Margarita
- Camputaro Luis
- Camsooksai Julie
- Canales Julieta
- Canete Fidelina
- Cani Alma
- Cano Anastasio Espejo
- Cao Deyan
- Cao Wenzhen
- Cao Ying
- Cao Zu Qing
- Capuzzi Fabio
- Cardenas Yenny
- Carey Annette
- Carney Dominic
- Carter Charlotte
- Casaioli Simona
- Castelain Vincent
- Castiglione Giacomo
- Cata Juan
- Cavaco Raquel
- Cengiz Melike
- Cerezo Franklin Dean
- Cesar Helena
- Cespedes Laura
- Chaboyer Wendy
- Chadwick Llesley
- Chang Shu Chuan
- Chang Youjin
- Chantziara Vasiliki
- Chao Yu
- Chaparro Javiera
- Chaparro Silvia
- Chapeta Edwin
- Chapman Carmel
- Charalabous Iwy
- Chatzis Marinos
- Chee Hyun Keun
- Chen Feifei
- Chen Haiyan
- Chen Hongjuan
- Chen Jingfang
- Chen Lei
- Chen Meili
- Chen Tianfei
- Chen Wenmin
- Chen Xiaoyan
- Chen Zhihong
- Cheng
- Cheng Jiyin
- Chime Christiana
- Chimunda Tim
- Chinardet Benoît
- Chovas Achilleas
- Christ Martin
- Christofis Christos
- Chueca Ramon Molina
- Chunhua Gao
- Cinel İsmail
- Ciorba Paolo
- Clark Michele
- Clement Ana Isabel
- Clesi Tara
- Cody Caitriona
- Collet Marie
- Collins Amy
- Coman Mary
- Conde Belen Burgos
- Conejo Isabel
- Constantinou Constantina
- Corcoran Ailesh
- Coremans Stefano
- Correia Malcolm C.
- Corso Amalia
- Cortegiani Andrea
- Cortellazi Paolo
- Cosano Rosario
- Cossu Maria
- Costa Humberto
- Cotoia Antonella
- Coyer Fiona
- Craig Geraldine
- Craig Jayne
- Cranmer Karen
- Cranshaw Julius
- Creber Peter
- Crone Petra
- Cui Xia
- Cummings Donna
- Cupitt Jason
- Curilen Veronica
- Czuczwar Miroslaw
- Dagooc Rica
- Dai Zhaoxing
- Dal Hayriye Cankar
- Dallaire Julie
- Das Sasidharan Nair Vishnu
- Daubin Cédric
- Davidow Jon
- Davidson Cheryl
- Dawn Frances
- Dayan Meneses
- de Almeida Angelica Olivetto
- de Anda Gilberto Felipe Vazquez
- De Bels David
- de Ceballos José Peral Gutierrez
- De Decker Koen
- De Haan Marina
- de Jesús Ortiz Alberto
- de la Ventana Ana Belén Sánchez
- De lange Dylan
- De Lange Dylan
- de Molina Serrano José Ivan Rodriguez
- De Montmollin Etienne
- De Pablo Ana María
- De Rosa Silvia
- De Sanctis Francesca
- De Schryver Nicolas
- De Wit Irene
- Dean Emiliano
- Debue Anne-Sophie
- Del Bosque Diez Rosa
- del Cotillo Mercedes
- del Mar Diaz Salcedo Maria
- Del Moral Armengol Mario
- Del Rio Cabajo Lorena
- del Rosario Villar Redondo M.
- del Valle Gimenez Graciela
- Delgado Carlos Castro
- Delgado Patricia
- Dellafiore Federica
- Delossantos Shella
- Delve Peter
- Demarré Liesbet
- Demirkiran Oktay
- Dendane Tarek
- Deng Xiaoqiong
- Depuydt Tanja
- Derbyshire Claire
- Derrick Helen
- Deschepper Mieke
- Deva Shanti Rudra
- Dhaliwal Jasdeep
- Di Gravio Valentina
- Di Risio Alessandro
- Di Yanhong
- Diakaki Chrisi
- Dias Sofia
- Diaz Ana
- Diaz Anna
- Diaz Monica Garcia
- Dieperink Willem
- Diers Anja
- Dikmen Yalım
- Dikmen Yalim
- Dilek Ozcengiz
- Dimoula Aikaterini
- Dimski Thomas
- Ding Min
- Ding Xinran
- Ding Yajun
- Ding Yanming
- Dlamini-Sserumaga Lomangisi
- Dobric Milena
- Dolenc Simon
- Dolgusevs Mihails
- Domenech Laura Claramunt
- Dong Jingwen
- Dong Yunchun
- Donvito Maria
- Dormans Tom
- Douschan Philipp
- Doyle Deirdre
- Dragoumanis Christos
- Du Guifang
- Duan Huan
- Dugernier Thierry
- Duggal Abhijit
- Dullenkopf Alexander
- Dungca Adonis
- Dunne Lisa
- Duran Karely
- Déserts Marc Danguy des
- D’Ambrosio Francesco
- D’Ambrosio Paolo
- Ebaid Maie
- Ebaid Maie Salem
- Efe Serdar
- Efthimiou Aikaterini
- Efthymiou Anna
- Egi Moritoki
- Egorova Natalya
- Ei Poe Poe
- Elatrous Souheil
- Elay Gülseren
- Elgammudi Mala
- Elhadi Ahmed
- Elhadi Muhammed
- Elhechmi Youssef Zied
- Elkhayari Mina
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- Thankamma Bindu
- Theisen Christian
- Thix Cyril
- Tholioti Thomai
- Thoma Giannoula
- Thomas Beverley
- Thompson Amy
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- Thomsen Tina Damgaar
- Thorpe Elaine
- Tian Eryun
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- Von Der Osten Ingrid
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- Wahab Sherliza
- Wahlbom Ewa
- Waibel Hansjoerg
- Wallin Ewa
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- Wan Jianhong
- Wan Yan
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- Wang Ying
- Wang Yingli
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- Watts Stacey
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- Wei Dongfang
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- Wei Ying
- Welters Ingeborg D.
- White Joanne
- White Nigel
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- Williams Lynne
- Wilting Rob
- Wise Robert
- Woods Justin
- Wright Kerry
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- Wu ShiFen
- Wu Xiaojun
- Wu Xiaoying
- Wu Yang
- Wu Yun
- Wu Zijing
- Xhindi Nordian
- Xia Chun Jie
- Xia Xinhua
- Xiao Lina
- Xiao Min
- Xiao Yan
- Xiaoyan Yang
- Xie Yan
- Xing Cynthia
- Xiong Yunfeng
- Xixi Li
- Xu Lina
- Xu Xiao
- Xu Xuelian
- Xu Yan
- Xue Xiujuan
- Yaghi Aktham
- Yakubu Yakubu H.
- Yamamoto Ryohey
- Yan Howe
- Yan Xiaoli
- Yan Yan
- Yang Fan
- Yang Fengling
- Yang Huai
- Yang Jing
- Yang Lei
- Yang Qiao
- Yang Shunzhu
- Yang Yanping
- Yang YongXia
- Yao Xiuying
- Yao Yanlan
- Yao Zhiru
- Ye Man
- Ye Mei
- Yeni Nomhle Princess
- Yeon-Joo Lee
- Yildiz İsmail
- Yilmaz Hakan
- Yin Hai
- Yin Li
- Young Charlotte
- Young-Jae Cho
- Yu Jing
- Yu Min
- Yu Tingting
- Yu Zhu Jun
- Yuan Cui
- Yuan Weilian
- Yuan Yuxia
- Yuchen Wu
- Yuemen Ly
- Yumei Chen
- Zahra Hajer Ben
- Zainudin Asmah
- Zakalik Graciela
- Zaki Ahmed
- Zalba-Etayo Begoña
- Zamora Purificacion Sanchez
- Zamorano Matias Jesús Flamm
- Zan Tao
- Zand Farid
- Zarei Fatemeh
- Zeng Jing Mei
- Zeng Qi
- Zepoy Sofia
- Zerman Avşar
- Zermeno Jorge Macias
- Zgrzheblovska Lesia
- Zhang Aizhi
- Zhang Baoke
- Zhang Feifei
- Zhang Guiping
- Zhang Hong
- Zhang Hongsu
- Zhang Hui
- Zhang Jing
- Zhang Jundi
- Zhang Libing
- Zhang Ling
- Zhang Na
- Zhang Wei
- Zhang Yali
- Zhang Ying
- Zhang Zhenxia
- Zhao Hui Min
- Zhao Lijuan
- Zhao Lina
- Zhao Qian
- Zhao Qingli
- Zhao Rong Hua
- Zhao Ronghua
- Zhao Wenwen
- Zhao Yingjuan
- Zhedaeva Marina
- Zheng Hong
- Zheng Jing
- Zheng Xianhong
- Zhigang Zhang
- Zhijuan Wang
- Zhiping Sun
- Zhivotneva Trina
- Zhou Yuming
- Zhu Guoyan
- Zhu JiFen
- Zhu Jin Yu
- Zivanovic-Posilovic Gordana
- Zorko Nika
- Zubareva Nadezhda
- Zuev Evgeniy
- Zueva Oksana
- Zulkifli Zulkifli
- Ágoston Zsuzsann
- Åkerman Eva
- Çelik Jale Bengi
- Ñamendys-Silva Silvio A.
- Özcan Beysim
- Özserezli Boğaç
- Ünlü Nurdan
- Čuljak Hemena
- Şentürk Evren
- Šuput Aleksandar
- Publication venue
- 'Organisation for Economic Co-Operation and Development (OECD)'
- Publication date
- 26/02/2021
- Field of study
Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat
Recommended from our members
Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
- Author
- Abdala Antonio
- Abidi Khalid
- Abillama Fayez François
- Abos Francisco Javier Saenz
- Aboufray Ahmed Ali
- Abregal Giancarlo
- Abroug Fekri
- Achilleos Eleni
- Acosta Ysica
- Adam Višnja Nesek
- Adamina Ileana
- Adams John
- Adamuz Jordi
- Adejumo Prisca Olabisi
- Adekola Oyebola
- Ademokun Jane
- Adenekan Anthony
- Adib Nik Azman Nik
- Adipa Faustina Excel
- Afonso Elsa
- Aganon Ferdinand
- Agarwal Sonika
- Aguirre Joaquin
- Aguirre Lydia Gallego
- Aguirre-Bermeo Hernan
- Ahmad Fatima Kasem El
- Ahmad Meraj
- Ahmed Hazem
- Ahn Jong-Joon
- Ahtiala Maarit
- Akbas Turkay
- Akdağ Devrim
- Akker Mustafa
- Akselsen Gro Ringstad
- Al-Alawi Maram Milud Said
- Alabuzidi Aya
- Alampi Daniela
- Albaiceta Guillermo Muñiz
- Albert Patricia
- Albrecht Lea
- Albrett Jonathan
- Alexandropoulou Paraskevi
- Alexandrou Anna
- Ali Ashwaq
- Ali Mohd Nazri
- Alias Anita
- Alkhumsi Soad Imhmed R.
- Allaert Silvie
- Allison Nicola
- Almekhlafi Ghaleb
- Alonso Helena Fernandez
- Alsheikhly Ahmed Subhy
- Alshrif Abdualhamid I
- Alvarenga Gloria
- Alvarez Diana
- Alvarez Gonzalo Martín
- Alvarez Gustavo Andres
- Alvarez Jorge Duerto
- Alvarez Josep Trenado
- Alvarez Raquel Garcia
- Alves Paulo
- Andersen Marit Hildegunn
- Andersen Yvonne
- Andresen Hanne
- Anisoglou Souzana
- Antonio Maria Gracia San
- Antunes Nelson
- Anvelt Eneli
- Aperocho Cristal April Jane
- Aponte Cesar
- Araya Paola
- Arcas María Luisa Bravo
- Arikan Huseyin
- Arntsen Wenche
- Arteta Arteta Donaldo S.
- Ashour Firas
- Assiri Amer
- Atchade Enora
- Ateya Zainab
- Attwood Ben
- Aucapina Alejandra
- Avalos Fernando
- Aves Emma
- Avogadro Prune
- Avramopoulou Lamprini
- Ay Mustafa
- Ay Serap Avcı
- Aya Umeda
- Ayala Maria
- Aydemir Semih
- Aydin Demet Tok
- Azencot Mazal
- Azoia Joao
- Baasanjav Battsetseg
- Babych Volodymyr
- Baccaro Fernando
- Badariotti Gustavo
- Bae Jung-Min
- Baek Jonghyun
- Baftiu Nehat
- Bagshaw Sean
- Bahrin Laila Kamaliah Kamalul
- Bai Dongmei
- Bai Xiaowu
- Baini Matías
- Bakas Apostolos
- Baker Helen
- Baker Nerilee
- Balasubramanian Madhu
- Balbay Abidin Oner
- Balon Sandrine
- Bantar Ana
- Banwarie Preveen
- Bao Guijun
- Baptiste-Savoie Jacqueline
- Barakat-Johnson Michelle
- Barefield Cindy
- Barkas Diane
- Barnes Christopher
- Barone Antonio
- Baronia Arvind
- Barr Louise
- Barreiro Emma Moreno
- Barros Elaine
- Barrowcliffe Suzanne
- Barrueco-Francioni Jesus Emilio
- Bartoli Julio Ricardo
- Baruah Rosaleen
- Bascary Carlos Alejandro
- Baskakov Danil
- Baskoro Windu
- Bastani Styliani
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- Ben-Hamouda Nawfel
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- de Almeida Angelica Olivetto
- de Anda Gilberto Felipe Vazquez
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- De Haan Marina
- de Jesús Ortiz Alberto
- de la Ventana Ana Belén Sánchez
- De lange Dylan
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- de Molina Serrano José Ivan Rodriguez
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- Dormans Tom
- Douschan Philipp
- Doyle Deirdre
- Dragoumanis Christos
- Du Guifang
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- Dugernier Thierry
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- D’Ambrosio Francesco
- D’Ambrosio Paolo
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- Efe Serdar
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- Efthymiou Anna
- Egi Moritoki
- Egorova Natalya
- Ei Poe Poe
- Elatrous Souheil
- Elay Gülseren
- Elgammudi Mala
- Elhadi Ahmed
- Elhadi Muhammed
- Elhechmi Youssef Zied
- Elkhayari Mina
- Ellazar Chris Gerome
- Eller Philipp
- Eltorai Ashley Szabo
- Enamorado Judy
- Enamorado Judy Enamorado
- Eneas Antony
- Eng Timothy
- Erdivanli Başar
- Erdogan Elif
- Eroglu Ahmet
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- Escalante Rosana Gabriela
- Espinosa Cristina Paños
- Esposito Romina
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- Etourneau Fabienne
- Evers Mirjam
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- Zhiping Sun
- Zhivotneva Trina
- Zhou Yuming
- Zhu Guoyan
- Zhu JiFen
- Zhu Jin Yu
- Zivanovic-Posilovic Gordana
- Zorko Nika
- Zubareva Nadezhda
- Zuev Evgeniy
- Zueva Oksana
- Zulkifli Zulkifli
- Ágoston Zsuzsann
- Åkerman Eva
- Çelik Jale Bengi
- Ñamendys-Silva Silvio A.
- Özcan Beysim
- Özserezli Boğaç
- Ünlü Nurdan
- Čuljak Hemena
- Şentürk Evren
- Šuput Aleksandar
- Publication venue
- Intensive Care Medicine
- Publication date
- 09/04/2021
- Field of study
The original version of this article unfortunately contained a mistake
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