389 research outputs found
Limb-Darkening of a K Giant in the Galactic Bulge: PLANET Photometry of MACHO 97-BLG-28
We present the PLANET photometric dataset for the binary-lens microlensing
event MACHO 97-BLG-28 consisting of 696 I and V-band measurements, and analyze
it to determine the radial surface brightness profile of the Galactic bulge
source star. The microlensed source, demonstrated to be a K giant by our
independent spectroscopy, crossed the central isolated cusp of the lensing
binary, generating a sharp peak in the light curve that was well-resolved by
dense (3 - 30 minute) and continuous monitoring from PLANET sites in Chile,
South Africa, and Australia. Our modeling of these data has produced stellar
profiles for the source star in the I and V bands that are in excellent
agreement with those predicted by stellar atmospheric models for K giants. The
limb-darkening coefficients presented here are the first derived from
microlensing, among the first for normal giants by any technique, and the first
for any star as distant as the Galactic bulge. Modeling indicates that the
lensing binary has a mass ratio q = 0.23 and an (instantaneous) separation in
units of the angular Einstein ring radius of d = 0.69 . For a lens in the
Galactic bulge, this corresponds to a typical stellar binary with a projected
separation between 1 and 2 AU. If the lens lies closer, the separation is
smaller, and one or both of the lens objects is in the brown dwarf regime.
Assuming that the source is a bulge K2 giant at 8 kpc, the relative lens-source
proper motion is mu = 19.4 +/- 2.6 km/s /kpc, consistent with a disk or bulge
lens. If the non-lensed blended light is due to a single star, it is likely to
be a young white dwarf in the bulge, consistent with the blended light coming
from the lens itself.Comment: 32 Pages, including 1 table and 9 postscript figures. (Revised
version has slightly modified text, corrected typo, and 1 new figure.)
Accepted for publication in 1999 Astrophysical Journal; data are now
available at http://www.astro.rug.nl/~plane
Probing the atmosphere of the bulge G5III star OGLE-2002-BUL-069 by analysis of microlense H alpha line
We discuss high-resolution, time-resolved spectra of the caustic exit of the
binary microlensing event OGLE 2002-BUL-69 obtained with UVES on the VLT. The
source star is a G5III giant in the Galactic Bulge. During such events, the
source star is highly magnified, and a strong differential magnification around
the caustic resolves its surface. Using an appropriate model stellar atmosphere
generated by the NextGEN code we obtained a model light curve for the caustic
exit and compared it with a dense set of photometric observations obtained by
the PLANET microlensing follow up network. We further compared predicted
variations in the H alpha equivalent width with those measured from our
spectra. While the model and observations agree in the gross features, there
are discrepancies suggesting shortcomings in the model, particularly for the H
alpha line core, where we have detected amplified emission from the stellar
chromosphere as the source star's trailing limb exited the caustic. This
achievement became possible by the provision of the OGLE-III Early Warning
System, a network of small telescopes capable of nearly-continuous
round-the-clock photometric monitoring, on-line data reduction, daily
near-real-time modelling in order to predict caustic crossing parameters, and a
fast and efficient response of a 8m-class telescope to a
``Target-Of-Opportunity'' observation request.Comment: 4 pages Latex, 3 figures, accepted for publication to astronomy and
astrophysics letter
The remnants of galaxy formation from a panoramic survey of the region around M31
In hierarchical cosmological models, galaxies grow in mass through the
continual accretion of smaller ones. The tidal disruption of these systems is
expected to result in loosely bound stars surrounding the galaxy, at distances
that reach times the radius of the central disk. The number,
luminosity and morphology of the relics of this process provide significant
clues to galaxy formation history, but obtaining a comprehensive survey of
these components is difficult because of their intrinsic faintness and vast
extent. Here we report a panoramic survey of the Andromeda galaxy (M31). We
detect stars and coherent structures that are almost certainly remnants of
dwarf galaxies destroyed by the tidal field of M31. An improved census of their
surviving counterparts implies that three-quarters of M31's satellites brighter
than await discovery. The brightest companion, Triangulum (M33), is
surrounded by a stellar structure that provides persuasive evidence for a
recent encounter with M31. This panorama of galaxy structure directly confirms
the basic tenets of the hierarchical galaxy formation model and reveals the
shared history of M31 and M33 in the unceasing build-up of galaxies.Comment: Published in Nature. Supplementary movie available at
https://www.astrosci.ca/users/alan/PANDAS/Latest%20news%3A%20movie%20of%20orbit.htm
HI intensity mapping : a single dish approach
We discuss the detection of large scale HI intensity fluctuations using a
single dish approach with the ultimate objective of measuring the Baryonic
Acoustic Oscillations and constraining the properties of dark energy. We
present 3D power spectra, 2D angular power spectra for individual redshift
slices, and also individual line-of-sight spectra, computed using the S^3
simulated HI catalogue which is based on the Millennium Simulation. We consider
optimal instrument design and survey strategies for a single dish observation
at low and high redshift for a fixed sensitivity. For a survey corresponding to
an instrument with T_sys=50 K, 50 feed horns and 1 year of observations, we
find that at low redshift (z \approx 0.3), a resolution of 40 arc min and a
survey of 5000 deg^2 is close to optimal, whereas at higher redshift (z \approx
0.9) a resolution of 10 arcmin and 500 deg^2 would be necessary. Continuum
foreground emission from the Galaxy and extragalactic radio sources are
potentially a problem. We suggest that it could be that the dominant
extragalactic foreground comes from the clustering of very weak sources. We
assess its amplitude and discuss ways by which it might be mitigated. We then
introduce our concept for a single dish telescope designed to detect BAO at low
redshifts. It involves an under-illumintated static 40 m dish and a 60 element
receiver array held 90 m above the under-illuminated dish. Correlation
receivers will be used with each main science beam referenced against an
antenna pointing at one of the Celestial Poles for stability and control of
systematics. We make sensitivity estimates for our proposed system and
projections for the uncertainties on the power spectrum after 1 year of
observations. We find that it is possible to measure the acoustic scale at
z\approx 0.3 with an accuracy 2.4% and that w can be measured to an accuracy of
16%.Comment: 20 pages, 20 figures, submitted to MNRA
The vertical distribution of ozone instantaneous radiative forcing from satellite and chemistry climate models
We evaluate the instantaneous radiative forcing (IRF) of tropospheric ozone predicted by four state-of-the-art global chemistry climate models (AM2-Chem, CAM-Chem, ECHAM5-MOZ, and GISS-PUCCINI) against ozone distribution observed from the NASA Tropospheric Emission Spectrometer (TES) during August 2006. The IRF is computed through the application of an observationally constrained instantaneous radiative forcing kernels (IRFK) to the difference between TES and model-predicted ozone. The IRFK represent the sensitivity of outgoing longwave radiation to the vertical and spatial distribution of ozone under all-sky condition. Through this technique, we find total tropospheric IRF biases from -0.4 to + 0.7 W/m(2) over large regions within the tropics and midlatitudes, due to ozone differences over the region in the lower and middle troposphere, enhanced by persistent bias in the upper troposphere-lower stratospheric region. The zonal mean biases also range from -30 to + 50 mW/m(2) for the models. However, the ensemble mean total tropospheric IRF bias is less than 0.2 W/m(2) within the entire troposphere
Limb-darkening measurements for a cool red giant in microlensing event OGLE 2004-BLG-482
Aims: We present a detailed analysis of OGLE 2004-BLG-482, a relatively
high-magnification single-lens microlensing event which exhibits clear
extended-source effects. These events are relatively rare, but they potentially
contain unique information on the stellar atmosphere properties of their source
star, as shown in this study. Methods: Our dense photometric coverage of the
overall light curve and a proper microlensing modelling allow us to derive
measurements of the OGLE 2004-BLG-482 source star's linear limb-darkening
coefficients in three bands, including standard Johnson-Cousins I and R, as
well as in a broad clear filter. In particular, we discuss in detail the
problems of multi-band and multi-site modelling on the expected precision of
our results. We also obtained high-resolution UVES spectra as part of a ToO
programme at ESO VLT from which we derive the source star's precise fundamental
parameters. Results: From the high-resolution UVES spectra, we find that OGLE
2004-BLG-482's source star is a red giant of MK type a bit later than M3, with
Teff = 3667 +/- 150 K, log g = 2.1 +/- 1.0 and an assumed solar metallicity.
This is confirmed by an OGLE calibrated colour-magnitude diagram. We then
obtain from a detailed microlensing modelling of the light curve linear
limb-darkening coefficients that we compare to model-atmosphere predictions
available in the literature, and find a very good agreement for the I and R
bands. In addition, we perform a similar analysis using an alternative
description of limb darkening based on a principal component analysis of ATLAS
limb-darkening profiles, and also find a very good agreement between
measurements and model predictions.Comment: Accepted in A&
Dopamine Modulates the Rest Period Length without Perturbation of Its Power Law Distribution in Drosophila melanogaster
We analyzed the effects of dopamine signaling on the temporal organization of rest and activity in Drosophila melanogaster. Locomotor behaviors were recorded using a video-monitoring system, and the amounts of movements were quantified by using an image processing program. We, first, confirmed that rest bout durations followed long-tailed (i.e., power-law) distributions, whereas activity bout durations did not with a strict method described by Clauset et al. We also studied the effects of circadian rhythm and ambient temperature on rest bouts and activity bouts. The fraction of activity significantly increased during subjective day and at high temperature, but the power-law exponent of the rest bout distribution was not affected. The reduction in rest was realized by reduction in long rest bouts. The distribution of activity bouts did not change drastically under the above mentioned conditions. We then assessed the effects of dopamine. The distribution of rest bouts became less long-tailed and the time spent in activity significantly increased after the augmentation of dopamine signaling. Administration of a dopamine biosynthesis inhibitor yielded the opposite effects. However, the distribution of activity bouts did not contribute to the changes. These results suggest that the modulation of locomotor behavior by dopamine is predominantly controlled by changing the duration of rest bouts, rather than the duration of activity bouts
Inferring stabilizing mutations from protein phylogenies : application to influenza hemagglutinin
One selection pressure shaping sequence evolution is the requirement that a protein fold with sufficient stability to perform its biological functions. We present a conceptual framework that explains how this requirement causes the probability that a particular amino acid mutation is fixed during evolution to depend on its effect on protein stability. We mathematically formalize this framework to develop a Bayesian approach for inferring the stability effects of individual mutations from homologous protein sequences of known phylogeny. This approach is able to predict published experimentally measured mutational stability effects (ΔΔG values) with an accuracy that exceeds both a state-of-the-art physicochemical modeling program and the sequence-based consensus approach. As a further test, we use our phylogenetic inference approach to predict stabilizing mutations to influenza hemagglutinin. We introduce these mutations into a temperature-sensitive influenza virus with a defect in its hemagglutinin gene and experimentally demonstrate that some of the mutations allow the virus to grow at higher temperatures. Our work therefore describes a powerful new approach for predicting stabilizing mutations that can be successfully applied even to large, complex proteins such as hemagglutinin. This approach also makes a mathematical link between phylogenetics and experimentally measurable protein properties, potentially paving the way for more accurate analyses of molecular evolution
The state of the Martian climate
60°N was +2.0°C, relative to the 1981–2010 average value (Fig. 5.1). This marks a new high for the record. The average annual surface air temperature (SAT) anomaly for 2016 for land stations north of starting in 1900, and is a significant increase over the previous highest value of +1.2°C, which was observed in 2007, 2011, and 2015. Average global annual temperatures also showed record values in 2015 and 2016. Currently, the Arctic is warming at more than twice the rate of lower latitudes
An Assay to Monitor HIV-1 Protease Activity for the Identification of Novel Inhibitors in T-Cells
The emergence of resistant HIV strains, together with the severe side-effects of existing drugs and lack of development of effective anti-HIV vaccines highlight the need for novel antivirals, as well as innovative methods to facilitate their discovery. Here, we have developed an assay in T-cells to monitor the proteolytic activity of the HIV-1 protease (PR). The assay is based on the inducible expression of HIV-1 PR fused within the Gal4 DNA-binding and transactivation domains. The fusion protein binds to the Gal4 responsive element and activates the downstream reporter, enhanced green fluorescent protein (eGFP) gene only in the presence of an effective PR Inhibitor (PI). Thus, in this assay, eGFP acts as a biosensor of PR activity, making it ideal for flow cytometry based screening. Furthermore, the assay was developed using retroviral technology in T-cells, thus providing an ideal environment for the screening of potential novel PIs in a cell-type that represents the natural milieu of HIV infection. Clones with the highest sensitivity, and robust, reliable and reproducible reporter activity, were selected. The assay is easily adaptable to other PR variants, a multiplex platform, as well as to high-throughput plate reader based assays and will greatly facilitate the search for novel peptide and chemical compound based PIs in T-cells
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