Organização, gestão e cuidado nutricional de pessoas com sobrepeso e obesidade na Atenção Primária à Saúde

Objective: To evaluate the organization, management, and nutritional care offered to overweight and obese individuals in primary healthcare (PHC) centers. Methods: A cross-sectional study was conducted with 54 professionals from PHC in the city of Goiânia-GO. Data were obtained using a semi-structured, self-administered electronic questionnaire. Results: The participating professionals were predominantly nurses (88.9%) with more than five years in their current position (79.6%). Regarding office infrastructure, including seating, only 11.1% reported adequate chairs and benches, while 33.3% reported adequate physical accessibility. Territory mapping was reported by 51.8% of professionals. The main strategies for organizing care and treatment were central regulation (79.6%), and referrals and counter-referrals (77.6%). Conclusion: The results of this study reflect that PHC in Goiânia-GO is in the process of implementing management services and nutritional care that meet the public policy standards envisaged for the prevention and management of overweight conditions and obesity.Objetivo: Avaliar a organização, gestão e o cuidado nutricional ofertado às pessoas com sobrepeso e obesidade na Atenção Primária à Saúde (APS). Métodos: Trata-se de um estudo transversal realizado com 54 profissionais da Atenção Primária à Saúde da cidade de Goiânia-GO. Os dados foram obtidos por meio do questionário eletrônico semiestruturado e autoaplicável. Resultados: Os profissionais participantes eram enfermeiros 88,9%, e com mais de cinco anos na função atual 79,6%. Ao analisar a infraestrutura e mobiliário, apenas 11,1% relataram cadeiras e bancos adequados, 33,3% acessibilidade física. O mapeamento do território foi referido por 51,8% dos profissionais. As principais estratégias para organização do cuidado e tratamento foram: central de regulação 79,6%, referência e contrarreferência 77,8%. Conclusão: Os resultados deste estudo refletem que a APS em Goiânia-GO, está em processo de implantação da gestão e cuidado nutricional que atendam às políticas públicas previstas para a prevenção e manejo do sobrepeso e obesidade

ABORDAGEM A ANSIEDADE: ESTRÁTÉGIAS DE MANEJO E BEM-ESTAR MENTAL

The purpose of this research is to develop practical, evidence-based interventions to prevent and treat anxiety, considering demographic differences and specific challenges. To achieve this objective, we conducted a narrative literature review in academic databases, such as PubMed, Scopus, SciELO, Virtual Health Library, Lilacs and Google Scholar. The inclusion criteria cover works published in the last 10 years, free of charge, available in full and related to the proposed theme. On the other hand, the exclusion criteria include works published outside the selected period, repeated, unrelated to the proposed theme and incomplete. In data analysis, 50 articles were read in full, in addition to consulting 2 websites to obtain epidemiological data. Of these, only 5 were included in the study. The theoretical framework was organized into distinct topics, providing a solid basis for the analysis of anxiety. These topics covered psychological theories that explore its origins and manifestations, biological factors that influence its development, and a variety of effective interventions in managing and treating this complex phenomenon. By approaching each topic separately, it was possible to examine in detail the multiple facets of anxiety , providing a clearer and more comprehensive view of this relevant topic. The research highlighted a growing concern about anxiety disorders, compounded by sociocultural pressures and contemporary challenges. This encompasses the incessant search for validation on social networks, as well as in the family and social spheres, generating increasing uncertainty in relation to social approval and the paradigms established in society.O propósito desta pesquisa é desenvolver intervenções práticas, embasadas em evidências, com o intuito de prevenir e tratar a ansiedade, considerando as diferenças demográficas e os desafios específicos. Para alcançar esse objetivo, conduzimos uma revisão narrativa de literatura em bases de dados acadêmicas, como PubMed, Scopus, SciELO, Biblioteca virtual de saúde, Lilacs e Google Scholar. Os critérios de inclusão abrangem trabalhos publicados nos últimos 10 anos, de acesso gratuito, disponíveis na íntegra e relacionados à temática proposta. Por outro lado, os critérios de exclusão compreendem trabalhos publicados fora do período selecionado, repetidos, não relacionados à temática proposta e incompletos.Na análise dos dados, foram lidos na íntegra 50 artigos, além de consultar 2 sites para obtenção de dados epidemiológicos. Destes, apenas 5 foram incluídos para compor o estudo. O referencial teórico foi organizado em tópicos distintos, proporcionando uma base sólida para a análise da ansiedade. Esses tópicos abordaram teorias psicológicas que exploram suas origens e manifestações, fatores biológicos que influenciam seu desenvolvimento, e uma variedade de intervenções eficazes na gestão e tratamento desse fenômeno complexo.Ao abordar cada tópico de forma separada, foi possível examinar detalhadamente as múltiplas facetas da ansiedade, proporcionando uma visão mais clara e abrangente deste tema relevante. A pesquisa destacou uma crescente inquietação em relação aos distúrbios de ansiedade, agravados por pressões socioculturais e desafios contemporâneos. Isso engloba a busca incessante por validação nas redes sociais, assim como nas esferas familiar e social, gerando uma crescente incerteza em relação à aprovação social e aos paradigmas estabelecidos na sociedade

Análise epidemiológica das Doenças Exantemáticas na infância no Nordeste

INTRODUCTION: Exanthematous diseases, with an emphasis on Measles and Rubella, are infectious diseases in which skin rash is the main clinical manifestation, but they can also present systemic manifestations. They are caused by viruses or bacteria and are common in medical practice, being quite prevalent in the pediatric age group. OBJECTIVE: To determine the epidemiological profile of exanthematous diseases in childhood, in all northeastern states, between the years 2018 and 2022. METHODOLOGY: This is a retrospective, quantitative and descriptive study, with data collection carried out in the System Information on Notifiable Diseases (SINAN), obtained through DATASUS. The states, year of notification, sex and age group were analyzed. RESULTS AND DISCUSSIONS: In total there were 751 cases in the 9 states of the Northeast. With a higher number of notifications in the state of Pernambuco 428 cases (56.99%), followed by Bahia 78 cases (10.38%) and with a lower number in Piauí, 16 cases (2.13%). In terms of gender, men account for a total of 385 (51.25%), and women 366 (48.73%), with a certain majority being male. Regarding the age group, up to 14 years old, the most affected are children under 1 year old, with 178 cases (23.7%). The year with the highest notifications was 2019, with a total of 556 cases (74.03%), followed by the year with 91 cases (12.11%). CONCLUSION: It is observed that even with campaigns and vaccines against exanthematous diseases (measles and rubella), which are offered in Primary Care, the number of children affected by these pathologies is still alarming. Through research, a greater incidence is observed in boys and children under 1 year of age, in the state of Pernambuco. Therefore, measures must be taken to provide greater protection for children and for better outcomes from these diseases.INTRODUÇÃO: As doenças exantemáticas, com ênfase no Sarampo e na Rubéola são enfermidades infectocontagiosas na qual tem a erupção cutânea como a principal manifestação clínica, mas também podem apresentar manifestações sistêmicas. São causadas por vírus ou bactérias e frequentes na prática médica, sendo bastante prevalente na faixa etária pediátrica. OBJETIVO: Determinar o perfil epidemiológico das doenças exantemáticas na infância, de todos os estados do nordeste, entre os anos de 2018 a 2022. METODOLOGIA: Trata-se de um estudo de caráter retrospectivo, quantitativo e descritivo, com coleta de dados feita no Sistema de Informação de Agravos de Notificação (SINAN), obtidos através do DATASUS. Foram analisados os estados, ano de notificação, sexo e faixa etária. RESULTADOS E DISCUSSÕES: No total foram 751 casos nos 9 estados do Nordeste. Com um número maior de notificações no estado do Pernambuco 428 casos (56,99%), seguido da Bahia 78 casos (10,38%) e com um menor número no Piauí, 16 casos (2,13%). Em relação ao sexo, os homens correspondem a um total de 385 (51,25%), e as mulheres 366 (48,73%), com certa maioria no sexo masculino. No tocante a faixa etária, até os 14 anos, a mais acometida é de crianças abaixo de 1 ano, com 178 casos (23,7%). O ano de agravo com maiores notificações foi o de 2019, com um total de 556 casos, (74,03%), seguido do ano de 2020, 91 casos (12,11%). CONCLUSÃO: Observa-se que mesmo com campanhas e vacinas contra as doenças exantemáticas (sarampo e rubéola), que são ofertadas na Atenção Básica, o número de crianças afetadas por essas patologias ainda é alarmante. Através das pesquisas, observa-se maior acometimento nos meninos e nos menores de 1 ano, no estado do Pernambuco. Dessa forma, medidas devem ser tomadas para maior proteção do público infantil e para melhores desfechos dessas doenças

Post-intervention Status in Patients With Refractory Myasthenia Gravis Treated With Eculizumab During REGAIN and Its Open-Label Extension

OBJECTIVE: To evaluate whether eculizumab helps patients with anti-acetylcholine receptor-positive (AChR+) refractory generalized myasthenia gravis (gMG) achieve the Myasthenia Gravis Foundation of America (MGFA) post-intervention status of minimal manifestations (MM), we assessed patients' status throughout REGAIN (Safety and Efficacy of Eculizumab in AChR+ Refractory Generalized Myasthenia Gravis) and its open-label extension. METHODS: Patients who completed the REGAIN randomized controlled trial and continued into the open-label extension were included in this tertiary endpoint analysis. Patients were assessed for the MGFA post-intervention status of improved, unchanged, worse, MM, and pharmacologic remission at defined time points during REGAIN and through week 130 of the open-label study. RESULTS: A total of 117 patients completed REGAIN and continued into the open-label study (eculizumab/eculizumab: 56; placebo/eculizumab: 61). At week 26 of REGAIN, more eculizumab-treated patients than placebo-treated patients achieved a status of improved (60.7% vs 41.7%) or MM (25.0% vs 13.3%; common OR: 2.3; 95% CI: 1.1-4.5). After 130 weeks of eculizumab treatment, 88.0% of patients achieved improved status and 57.3% of patients achieved MM status. The safety profile of eculizumab was consistent with its known profile and no new safety signals were detected. CONCLUSION: Eculizumab led to rapid and sustained achievement of MM in patients with AChR+ refractory gMG. These findings support the use of eculizumab in this previously difficult-to-treat patient population. CLINICALTRIALSGOV IDENTIFIER: REGAIN, NCT01997229; REGAIN open-label extension, NCT02301624. CLASSIFICATION OF EVIDENCE: This study provides Class II evidence that, after 26 weeks of eculizumab treatment, 25.0% of adults with AChR+ refractory gMG achieved MM, compared with 13.3% who received placebo

Minimal Symptom Expression' in Patients With Acetylcholine Receptor Antibody-Positive Refractory Generalized Myasthenia Gravis Treated With Eculizumab

The efficacy and tolerability of eculizumab were assessed in REGAIN, a 26-week, phase 3, randomized, double-blind, placebo-controlled study in anti-acetylcholine receptor antibody-positive (AChR+) refractory generalized myasthenia gravis (gMG), and its open-label extension

Penilaian Kinerja Keuangan Koperasi di Kabupaten Pelalawan

This paper describe development and financial performance of cooperative in District Pelalawan among 2007 - 2008. Studies on primary and secondary cooperative in 12 sub-districts. Method in this stady use performance measuring of productivity, efficiency, growth, liquidity, and solvability of cooperative. Productivity of cooperative in Pelalawan was highly but efficiency still low. Profit and income were highly, even liquidity of cooperative very high, and solvability was good

Severe early onset preeclampsia: short and long term clinical, psychosocial and biochemical aspects

Preeclampsia is a pregnancy specific disorder commonly defined as de novo hypertension and proteinuria after 20 weeks gestational age. It occurs in approximately 3-5% of pregnancies and it is still a major cause of both foetal and maternal morbidity and mortality worldwide1. As extensive research has not yet elucidated the aetiology of preeclampsia, there are no rational preventive or therapeutic interventions available. The only rational treatment is delivery, which benefits the mother but is not in the interest of the foetus, if remote from term. Early onset preeclampsia (<32 weeks’ gestational age) occurs in less than 1% of pregnancies. It is, however often associated with maternal morbidity as the risk of progression to severe maternal disease is inversely related with gestational age at onset2. Resulting prematurity is therefore the main cause of neonatal mortality and morbidity in patients with severe preeclampsia3. Although the discussion is ongoing, perinatal survival is suggested to be increased in patients with preterm preeclampsia by expectant, non-interventional management. This temporising treatment option to lengthen pregnancy includes the use of antihypertensive medication to control hypertension, magnesium sulphate to prevent eclampsia and corticosteroids to enhance foetal lung maturity4. With optimal maternal haemodynamic status and reassuring foetal condition this results on average in an extension of 2 weeks. Prolongation of these pregnancies is a great challenge for clinicians to balance between potential maternal risks on one the eve hand and possible foetal benefits on the other. Clinical controversies regarding prolongation of preterm preeclamptic pregnancies still exist – also taking into account that preeclampsia is the leading cause of maternal mortality in the Netherlands5 - a debate which is even more pronounced in very preterm pregnancies with questionable foetal viability6-9. Do maternal risks of prolongation of these very early pregnancies outweigh the chances of neonatal survival? Counselling of women with very early onset preeclampsia not only comprises of knowledge of the outcome of those particular pregnancies, but also knowledge of outcomes of future pregnancies of these women is of major clinical importance. This thesis opens with a review of the literature on identifiable risk factors of preeclampsia

Search for heavy resonances decaying to two Higgs bosons in final states containing four b quarks

A search is presented for narrow heavy resonances X decaying into pairs of Higgs bosons (H) in proton-proton collisions collected by the CMS experiment at the LHC at root s = 8 TeV. The data correspond to an integrated luminosity of 19.7 fb(-1). The search considers HH resonances with masses between 1 and 3 TeV, having final states of two b quark pairs. Each Higgs boson is produced with large momentum, and the hadronization products of the pair of b quarks can usually be reconstructed as single large jets. The background from multijet and t (t) over bar events is significantly reduced by applying requirements related to the flavor of the jet, its mass, and its substructure. The signal would be identified as a peak on top of the dijet invariant mass spectrum of the remaining background events. No evidence is observed for such a signal. Upper limits obtained at 95 confidence level for the product of the production cross section and branching fraction sigma(gg -> X) B(X -> HH -> b (b) over barb (b) over bar) range from 10 to 1.5 fb for the mass of X from 1.15 to 2.0 TeV, significantly extending previous searches. For a warped extra dimension theory with amass scale Lambda(R) = 1 TeV, the data exclude radion scalar masses between 1.15 and 1.55 TeV

Measurement of associated W plus charm production in pp collisions at √s=7 TeV

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