10 research outputs found
Observational constraints on the co-evolution of supermassive black holes and galaxies
- Author
- Alonso-Herrero
- Barger
- Barth
- Bell
- Bell
- Bell
- Bell
- Bell
- Bell
- Binney
- Borys
- Brand
- Brown
- Bundy
- Chartas
- Chary
- Cox
- D. Schiminovich
- Dale
- Dickinson
- Donley
- Donley
- Drory
- E. F. Bell
- F. Fontanot
- Ferrarese
- Fontana
- G. H. Rieke
- Gabor
- Gebhardt
- Granato
- Greene
- Grogin
- H.-W. Rix
- Haiman
- Ho
- Hopkins
- Hopkins
- Hopkins
- Hopkins
- Hopkins
- Häring
- Häußler
- Jogee
- K. Jahnke
- K. Meisenheimer
- Kaspi
- Kollmeier
- Kormendy
- La Franka
- Lagache
- Lauer
- Lauer
- Le Floc'h
- Lehmer
- Magorrian
- Marconi
- Martin
- McIntosh
- McNamara
- Miyaji
- Morrissey
- Murray
- Nandra
- Noeske
- Pannella
- Papovich
- Peng
- Peng
- Pierce
- Pérez-González
- R. S. Somerville
- Rafferty
- Reddy
- Richards
- Richards
- Rieke
- Rieke
- Rix
- Robaina
- Robertson
- Robertson
- Rudnick
- Sanders
- Schiminovich
- Schiminovich
- Shi
- Shields
- Silk
- Silverman
- Smolčić
- Thomas
- Trager
- Tremonti
- Treu
- Treu
- Ueda
- van der Wel
- Vestergaard
- Wandel
- Watson
- Wolf
- Woo
- Wyithe
- X. Z. Zheng
- Zheng
- Zheng
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2009
- Field of study
The star formation rate (SFR) and black hole accretion rate (BHAR) functions
are measured to be proportional to each other at z < ~3. This close
correspondence between SF and BHA would naturally yield a BH mass-galaxy mass
correlation, whereas a BH mass-bulge mass correlation is observed. To explore
this apparent contradiction we study the SF in spheroid-dominated galaxies
between z=1 and the present day. We use 903 galaxies from the COMBO-17 survey
with M* >2x10^10M_sun, ultraviolet and infrared-derived SFRs from Spitzer and
GALEX, and morphologies from GEMS HST/ACS imaging. Using stacking techniques,
we find that <25% of all SF occurs in spheroid-dominated galaxies (Sersic index
n>2.5), while the BHAR that we would expect if the global scalings held is
three times higher. This rules out the simplest picture of co-evolution, in
which SF and BHA trace each other at all times. These results could be
explained if SF and BHA occur in the same events, but offset in time, for
example at different stages of a merger event. However, one would then expect
to see the corresponding star formation activity in early-stage mergers, in
conflict with observations. We conclude that the major episodes of SF and BHA
occur in different events, with the bulk of SF happening in isolated disks and
most BHA occurring in major mergers. The apparent global co-evolution results
from the regulation of the BH growth by the potential well of the galactic
spheroid, which includes a major contribution from disrupted disk stars.Comment: 14 pages, 5 figures, accepted for publication in Ap
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
- Author
- Abad-Motos Ane
- Abbas Ahmed M.
- Abbas Mostafa
- Abbasi Mujeeb
- Abbott Tom
- Abd Karim Muhammad Fairuz Shah
- Abdalaal Ibrahim
- Abdel-Galil Khalid
- Abdelemam Rania
- Abdelgawad Abdalrahman
- Abdelkarim Maryam
- Abdelkhalek Mohamed
- Abdelmageed Abdelfatah
- Abdelmawgoud Sherif
- Abdelmohsen Sarah
- Abdelrahman Ahmed Saber
- Abdelrahman Mostafa
- Abdelwahab Khaled
- Abdou Hossam
- Abdulai Darling Ramatu
- Abdulkhaleq Marwa
- Abdullah Bahiyah
- Abdulsalam Khalifa
- Abdulsalam Shuaib
- Abdur-Rahman Lukman
- Abdus-Salam Rukiyat
- Abdussalam Hameedat Opeyemi
- Abebrese John Tabiri
- Abeldaño Ariel
- Abou-Khalil Jad
- Abou-Taleb Hisham
- Abozid Anwaar
- Abozied Hesham
- Abrate Alberto
- Abu-Zaid Ahmed
- Abubakar Mohammed Kabir
- Abud Burçin
- Abuzaid Mohammed
- Adam Albushra Altayeb
- Adamina Michel
- Adamou Harissou
- Adamu Auwal
- Adamu Kabir Musa
- Adanu Kekeli
- Adebara Idowu
- Adebola Oluwaseyi
- Ademuyiwa Adesoji
- Adeniran Abiodun
- Adepiti Akinfolarin
- Aderogba Adeleke Akeem
- Adesunkanmi Abdulhafiz
- Adeyeye Ademola
- Adisa Adewale
- Adjeso Theophilus Justus Kofi
- Ads Adel Mohamed
- Ads Alaa Mohamed
- Adu-Aryee Nii Armah
- Adumah Collins
- Afzal Irrum
- Agapov Mikhail
- Agarwal Gaurav
- Agarwal Ravi
- Agbeko Anita Eseenam
- Agbeno Evans Kofi
- Agbonrofo Peter
- Agboola Oluseyi
- Aggarwal Gaurav
- Aghadi Ifeanyi
- Aghtarafi Natasha
- Agrawal Amit
- Agresta Ferdinando
- Aguado Héctor J.
- Aguilera-Arevalo Maria-Lorena
- Aherne Thomas
- Ahmad Aline
- Ahmad Maleeha
- Ahmad Misbahu
- Ahmad Sarwat
- Ahmad Shahzaib
- Ahmad Shoaib
- Ahmed Hayat Tarig Abdelhafiz
- Ahmed Khalid
- Ahmed Sharwany
- Ahmed Shima
- Ahmed Usama
- Aisuodionoe-Shadrach Oseremen
- Aitken Sarah
- Ajenifuja Kayode
- Ajiya Abdulrazak
- Akeel Nouf
- Akin Emrah
- Akinajo Opeyemi
- Akinyemi Tosin
- Akrida Ioanna
- Aktokmakyan Talar Vartanoglu
- Akwaisah Ayoub
- Al Bettar Osama
- Al-Badawi Ismail A.
- Al-Juaifari Maytham
- Al-Khyatt Waleed
- Al-Mallah Abdullah
- Al-Nusairi Ahmed
- Al-Saadi Nina
- Al-Sayaghi Khaled
- Al-Shaiji Tariq
- Al-Shehari Mohammed
- Al-Touny Aiman
- Al-Touny Shimaa A.
- Aladawi Omar
- Aladna Abdallah
- Alali Mahmoud
- Alam Mahmood
- Alam Mohammed Shadrul
- Alarabi Rehab
- Alawneh Yazan
- Alayande Barnabas
- Albanese Erminia
- Albayadi Eslam
- Albdour Maram
- Alconchel Felipe
- Alderazi Amer
- Alegbeleye Bamidele
- Alekberli Tural
- Alemu Misganaw Alemu Adimass
- Alexander Philip
- Alfieri Alex
- Algahtany Khaled
- Algarni Kamal
- Alhamad Ameen
- Alhamid Mohammad
- Alharmi Rawan A. Rahman
- Alharthi Mohammed
- Alhazmi Barrag
- Ali Mohamed Shafi Mahboob
- Ali Stephen
- Alibrahim Hidar
- Aljaaly Hattan
- Aljaiuossi Anas
- Aljanadi Firas
- Aljiffry Murad
- Aljirdabi Noof
- Alkahlan Mohammed
- Alkhalifa Elmustafa
- Alkhatib Sondos
- Alkhatieb Maram
- Allan Anna
- Almarshad Felwa
- Almgla Naser
- Almhimid Ali
- Almiqlash Bushray
- Almoshantaf Mohammad Badr
- Almutairi Abdulmjeed
- Alnsour Abed Alfattah Mahmoud
- Alobied Majd
- Alomar Osama
- Alonso Jesús Aarón Martínez
- Alonso Manuel Diez
- Alonso Nestor Fabian Pedraza
- Alonso Veronica
- Alqallaf Abdullah
- Alqaseer Asma
- Alrayes Bourhan
- Alsefri Maryam
- Alser Osaid
- Alsharif Mohammed
- Alsori Mohamed
- Altaf Abdulmalik
- Altinel Yuksel
- Altiner Saygin
- Altouny Ahmad
- Altun Demet
- Alvarez Natalia
- Alvarez-Lozada Luis Adrian
- Alvi Abdul
- Alwael Athari
- Alwash Mohammed
- Alyami Ziyad
- Alyousef Mohammed
- Alzahrani Saud
- Alzerwi Nasser
- Amin Shivang
- Amir Mohammed
- Ammar Ahmed Siddique
- Ammendola Michele
- Amores Remedios Revilla
- Amrayev Sultan
- Anastasiadou Sofia
- Ancans Guntis
- Anderson Caroline
- Andreani Lorenzo
- Andreotti Dario
- Andreuccetti Jacopo
- Andrianakis Alexandros
- Andro Christophe
- Anesi Alexandre
- Angamuthu Stephen
- Angeles Martina Aida
- Angelico Roberta
- Angelis Fragkiskos
- Angelou Dimitrios
- Angelou Kyveli
- Angulo Victor Pinto
- Anjum Arfa
- Anjum Muhammad Ayyub
- Annicchiarico Alfredo
- Anoldo Pietro
- Ansaloni Luca
- Anthoulakis Christos
- Antonelli Amedeo
- Anwar Mohamed
- Anwar Sumadi Lukman
- Anwer Mariyah
- Anyanwu Lofty-John
- Apostolou Christos
- Apostolou Konstantinos
- Appiah-Kubi Adu
- Aprea Giovanni
- Arbab Hana
- Archer James
- Ardura Francisco
- Aremu Muyiwa
- Arif Tahera
- Arkani Samara
- Armatura Giulia
- Armijos Daniel
- Arnaout Ali
- Arnaoutoglou Eleni
- Arnaud Alexis P.
- Arneja Jugpal
- Arrangoiz Rodrigo
- Arshad Muhammad
- Arthur Joshua
- Ashcroft James
- Ashford Bruce
- Ashraf Fariha
- Asiimwe Daniel
- Asirifi Samuel Amoako
- Asla Amir
- Aslam Ramisha
- Aspide Raffaele
- Ataya Karim
- Ateca Ibabe Villalabeitia
- Atici Semra Demirli
- Atis Gokhan
- Atkins William
- Atkinson Kate
- Attwood Joseph
- Auerkari Aino
- Augestad Knut Magne
- Augustin Goran
- Aujayeb Avinash
- Avella Pasquale
- Awad Ahmed K.
- Awad Hadeel
- Awad Rabih
- Awad Selmy
- Ayad Kusay
- Ayana Birhanu
- Aydin Yener
- Ayeni Funbi
- Aytac Erman
- Azab Ahmed
- Azami Rizwan
- Azize Diallo Abdoul
- Azzam Ahmed Y.
- Azzis Olivier
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- Badran Saif
- Baduell Albert
- Baeesa Saleh
- Baertschiger Reto
- Bafaquh Mohammed
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- Bahrami-Hessari Michael
- Baia Marco
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- Bailey Karen
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- Bajaj Ankur
- Bajunaid Khalid
- Balagobi Balasingam
- Balasubramanian Ishwarya
- Balduzzi Alberto
- Baldwin Alexander
- Balla Andrea
- Balogh Zsolt J.
- Balogun James A.
- Balogun Simon
- Baloyiannis Ioannis
- Ban Vin Shen
- Bandyopadhyay Samik Kumar
- Bandyopadhyay Soham
- Banerjee Sumit
- Banipal Gurpreet Singh
- Banky Balazs
- Bannone Elisa
- Bansal Sujesh
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- Belzile Etienne
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- Bergkvist David Julià
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- Bharathan Rasiah
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- Borges Miguel Fróis
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- Carretero Manuel Moriche
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- Carvello Michele
- Casagranda Biagio
- Cassese Gianluca
- Cassinotti Elisa
- Castagnini Francesco
- Castaldi Antonio
- Castaño Mario
- Castaño-Leon Ana M.
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- Castro Ernes John
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- Caubet Maria Mercedes
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- Cerovac Anis
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- Chaplin Helen
- Charalabopoulos Alexandros
- Chatzikomnitsa Paraskevi
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- Chaudhary Muhammad Hamid
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- Chauhan Munish
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- Cheetham Mark
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- Chevallay Mickael
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- Chowdhury Mahbub
- Chowdhury Sharfuddin
- Chowdhury Subhadip Pal
- Christidis Panagiotis
- Christodoulidis Gregory
- Christodoulou Prokopis
- Chrysovitsiotis Georgios
- Chu Michael Jen Jie
- Chukwu Isaac
- Chwat Carina
- Cianci Pasquale
- Cicerchia Pierfranco Maria
- Ciftci Ahmet Burak
- Cil Aylin Pelin
- Cillara Nicola
- Cina Caterina
- Ciniero Valeria
- Cioffi Stefano Piero Bernardo
- Cipolla Calogero
- Cisneros Juan Roberto Torres
- Ciubotaru Cezar
- Claireaux Henry
- Clancy Cillian
- Claret Guillem
- Clegg Rachael
- Clementi Marco
- Clerc Daniel
- Clune Edward
- Coates Amy
- Cobianchi Lorenzo
- Coccolini Federico
- Cockbain Andrew J.
- Cohnert Tina
- Coimbra Fernandez
- Cokan Andrej
- Colak Elif
- Colasanti Roberto
- Cole Simon
- Collins Michelle L.
- Colombari Renan Carlo
- Colombo Francesco
- Colucci Nicola
- Colás-Ruiz Enrique
- Consani Heitor
- Conso Christel
- Consorti Giuseppe
- Conte Luigi Eduardo
- Conti Alfredo
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- Coughlin Patrick
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- Crichton Robert
- Critchley Rebecca
- Croghan Stefanie M.
- Cross George W. V.
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- Cullinane Carolyn
- Cullis Paul
- Cunha Miguel F.
- Cunningham Brian
- Currò Giuseppe
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- Cutmore Carina
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- D'Acapito Fabrizio
- D'Addino José Luis
- D'Amico Alessia
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- Davies Mark
- Davies Richard Justin
- Davis Amelia
- Dawson Amanda Caroline
- Dawson Jonathon
- Dbouk Samer
- De Alarcón Jaime Rodríguez
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- De La Infiesta García Carlos
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- De La Rosa-Estadella Marta
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- De Oliveira Gabriel Paiva
- De Pastena Matteo
- De Simone Veronica
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- De Vega Sánchez Blanca
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- Demetriades Andreas K
- Demetriou Charis
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- Djama Zakarya
- Djedovic Gabriel
- Doerner Johannes
- Doherty Daniel
- Dolci Giampiero
- Domanin Maurizio
- Domingo Marta María Arroyo
- Dominguez-Rosado Ismael
- Don Cristine Pathirannehalage
- Donkin Ian
- Donmez Emin Erhan
- Donoghue Sophie
- Donovan Richard
- Dornseifer Mamun David
- Dorovinis Panagiotis
- Douglas Deborah
- Downey Candice
- Doyle Alex
- Doǧan Lütfi
- Dragisic Vedran
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- Drasovean Radu
- Dreger Nici Markus
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- Dube Surya Kumar
- Dudi-Venkata Nagendra
- Duffy Caoimhe
- Dulskas Audrius
- Dunne Ben
- Dural Ahmet Cem
- Duran Erik Efrain Sosa
- Duro Agustin
- Durrani Abdullah
- Dyas Adam
- Dzhumabaev Khasan
- Dziakova Jana
- Dzogbefia Mawutor
- Díaz Jeancarlos Trujillo
- Dölker Theresa
- Eardley Nicola
- Ebrahim Abdulla
- Echieh Chidiebere Peter
- Edwards John
- Efetov Sergey
- Efremov Sergey
- Egan Richard
- Eiras Miguel Angel Freiria
- Eisa Elamin
- Ekor Oluwayemisi
- Ekwen Gerald
- Ekwunife Okechukwu Hyginus
- El Assaad Hadi
- El Boghdady Michael
- El Tayeb Essam Eldien Abuobaida Banaga Hag
- El-Boghdadly Kariem
- El-Hussuna Alaa
- El-Kassas Mohamed
- Elagili Ahmed
- Elahi Zain
- Elbadawy Merihan A.
- Elbahnasawy Mohamed
- Elbe Peter
- Elboraei Rahma
- Eldabaa Mohamed
- Elebute Olumide
- Elfeki Hossam
- Elfiky Mahmoud
- Elgazar Amr
- Elghadban Hosam
- Elhadi Muhammed
- Elhassan Wael Atif Fadl
- Elkazaz Ahmed
- Ellafi Amera Ali Dakheel
- Elliot R.
- Elnour Moheyaldien Ahmed Elamin
- Elsadek Menan
- Elsahli Saifaleslam
- Elsalhawy Shady
- Elsayem Karam
- Elshahawy Mahmoud Abdelaziz Mohamed
- Elsherbiny Ahmed
- Eltayeb Momin
- Elzwai Suha
- Emara Moataz Maher
- Embarek Hussein
- Emile Sameh
- Emmanuel Muhawenimana
- Enciu Octavian
- English Camilla
- Enodien Bassey
- Enwerem Kenneth
- Erel Serap
- Ergenç Merve
- Ergenç Muhammer
- Erginöz Ergin
- Eroglu Atilla
- Escobar Pedro
- Escobedo Francisco Jose Barbosa
- Escrevente Ricardo
- Eskinazi Diego
- Esposito Sofia
- Eugene Muneza
- Ezanno Anne-Cecile
- Ezeanochie Michael
- Ezeme Constantine
- Ezenwa Ekene
- Ezomike Uchechukwu
- Fadalla Tarig
- Fadel Zahir T
- Fahim Margo Medhat Fouad
- Fahmy Ali
- Faiz Javaria
- Fajardo Rafael Torres
- Fakhradiyev Ildar
- Fallah Jean-Michel
- Familiari Pietro
- Fang Clarissa Ern Hui
- Faponle Folayemi
- Farhan-Alanie Muhamed
- Farid Shahzaib
- Farooq Muhammad
- Fatima Mishal
- Fayad Elsayed A.
- Federer Simon
- Federico Nicoletta Sveva Pipitone
- Feeney Kaylem
- Fehervari Matyas
- Fekaj Enver
- Fernandez Laura Gomez
- Fernández Julio Domenech
- Ferracci Federica
- Ferrara Francesco
- Ferrari Davide
- Ferrario Luca
- Ferreli Fabio
- Ferrer Antonio Perez
- Ferrer Ursula María Jariod
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- Ragozzino Roberta
- Rahman Atiqur
- Rahy-Martín Aida Cristina
- Rai Lajpat
- Raimondo Diego
- Raja Anand
- Rajan Shiv
- Rajendram Rajkumar
- Raji Hadijat Olaide
- Ramasamy Ashok
- Ramely Rosnelifaizur
- Ramli Roszalina
- Rammohan Ashwin
- Ramos Ángel Cilleruelo
- Rampersad Lisa
- Ramzanali Shireen
- Rangasamy Karthick
- Rani Jyotsna
- Ranucci Maria Chiara
- Raphael Marie-Claire
- Raptis Dimitri Aristotle
- Rasheed Aqsa
- Rashid Isbah
- Ratto Carlo
- Rauf Umme Habiba Abdul
- Raurich-Leandro Jordi
- Rausa Emanuele
- Raut Chandrajit
- Raut Monish
- Ravindra Raevin
- Raymond Thomas
- Rayner Anthony
- Raza Muhammad Asif
- Recinos Gustavo
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- Redondo Nuria Villacé
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- Riccetti Camilla
- Richard H.
- Rickard Jennifer
- Rincón Natalia Andrea Rivera
- Ripollés-Melchor Javier
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- Rodrigues Sara Castanheira
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- Rodriguez Magdiel
- Rodriguez-Lopez Mario
- Rodríguez Lorena Varela
- Rokohl Alexander Christopher
- Roland Christina L
- Rolinger Jens
- Romano Angela
- Romano Maurizio
- Romanzi Andrea
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- Sahni Arun
- Sahu Mo
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- Sakr Ahmed
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- Saleh Ma'Moun
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- Salem Moacyr
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- Schweitzer Donald
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- Sholadoye Tunde T.
- Shoukrie Shoukrie I. M.
- Shrestha Rashmit
- Siboe Mark
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- Singer Georg
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- Slavchev Mihail
- Sleem Adham
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- Smith A.
- Smolle-Juettner Freyja-Maria
- Sodhai Vivek
- Sofi Khalid
- Sohrabi Catrin
- Soibiharry Adaiah
- Sokolov Manol
- Solaini Leonardo
- Sole Oriol Martin
- Sole-Sedeno Josep M.
- Soljic Martina
- Solli Piergiorgio
- Soon Wai Cheong
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- Sotudeh Mohadeseh
- Souadka Amine
- Soucheiron Maria Coronas
- Soytas Mustafa
- Sozzi Giulio
- Sparavigna Marco
- Spartalis Michael
- Spellar Kayleigh
- Spiers Harry V. M.
- Spina Alfio
- Spriano Giuseppe
- Squiers John
- Stabler Robert
- Stamatakis Emmanouil
- Stamatis Konstantinos
- Starr Nichole
- Stather Philip
- Stevens Sean
- Stevenson Andrew
- Stewart Grant D.
- Stijns Jasper
- Stogowski Piotr Tomasz
- Stoleriu Mircea Gabriel
- Stoyanov Vladislav
- Street John
- Strotmann Johanna Josefine
- Stroumpoulis Konstantinos
- Su Yu-Xiong
- Suarez Sara Busto
- Subramani Yamini
- Subramaniam Sentilnathan
- Sue-Chue-Lam Colin
- Suer Muhammed Salih
- Sulaiman Bilal
- Sultania Mahesh
- Sundarraju Shalini
- Sungurtekin Hulya
- Suresh Sreelakshmi
- Surya Ilham Utama
- Swed Sarya
- Syllaios Athanasios
- Symeonidis Dimitrios
- Szabómihályová Katarína
- Szakmany Tamas
- Szatmary Peter
- Sztipits Tamás
- Szyluk Karol
- Sá-Marta Eduarda
- Sánchez Alberto Cabañero
- Sánchez Rosa
- Sánchez-Guillén Luis
- Süleyman Marlen
- Tadic Boris
- Taha Anas
- Taha-Mehlitz Stephanie
- Tailor Bhavesh
- Taj Eldeen Samaher Taj Eldeen Hassan
- Takeda Flavio Roberto
- Takkenberg Marijn
- Talat Nabila
- Tallon-Aguilar Luis
- Talwar Rishi
- Tamayo Beatriz Villota
- Tamburello Sara
- Tamini Nicolò
- Tammo Ömer
- Tamoos Khalil
- Tampaki Ekaterini Christina
- Tampakis Athanasios
- Tan Chih Ying
- Tan Shawn Jia Hwang
- Tanal Mert
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- Tang Alethea
- Tang Yita
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- Tarek Ahmed
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- Tashkandi Wail
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- Tatsis Dimitris
- Tawalbeh Ra'Fat
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- Tebha Sameer
- Techapongsatorn Suphakarn
- Teixeira Pedro
- Tejero-Pintor Francisco J.
- Tellez Karla Susana Martin
- Tellez Luis Garcia-Sancho
- Thaha Mohamed Adhnan
- Thakar Sumit
- Thaw May Htoo
- Theivendran Kanthan
- Thekkinkattil Dinesh
- Theochari Nikoletta
- Theodoropoulos George
- Theophilidou Elena
- Thereska Dariel
- Thiruchandran Gajendiran
- Thomakos Nikolaos
- Thomas Bradley
- Thomas Jerin Jose
- Thuduvage Vasanthika
- Thumbadoo Ruben
- Tian Sarah
- Tidjane Anisse
- Tirloni Luca
- Toia Francesca
- Tokidis Evripidis
- Tokocin Merve
- Tolani Musliu Adetola
- Toma Elena Adelina
- Tomasicchio Giovanni
- Tomlinson James
- Tonini Valeria
- Torre Beatrice
- Torregrosa Cristina
- Torun Bahar Canbay
- Tottman R.
- Tousidonis Manuel
- Trabulsi Nora
- Tranca Sebastian
- Trebol Jacobo
- Trejo-Avila Mario
- Triantafyllou Alexandra
- Triantafyllou Tania
- Trifunovski Aleksandar
- Tripathi Manjul
- Tripathi Prashant
- Tripathy Sujit
- Trivik-Barrientos Felipe
- Trostchansky Ivan
- Trulson Alexander
- Trungu Sokol
- Truss Adam
- Tsakiridis Ioannis
- Tsakiridis Nikolaos
- Tsiantoula Paraskevi
- Tsironis Dimitrios
- Tsolakidis Alexandros
- Tsoulfas Georgios
- Tucker Olga
- Tuech Jean Jacques
- Turan Alparslan
- Turi Stefano
- Turna Akif
- Turrado-Rodriguez Victor
- Turri Giulia
- Tutino Roberta
- Tuyishime Eugene
- Tzelves Lazaros
- Tzima Ioanna
- Tzimas George
- Ubiali Paolo
- Ubom Akaninyene Eseme
- Ugwu Aloy Okechukwu
- Ugwu Ebere
- Ugwu Ifeanyichukwu
- Ul Huda Maria Noor
- Ulas Ali Bilal
- Uldry Emilie
- Ulgur Hanife Seyda
- Ulkucu Attila
- Ulman Elif Akbas
- Ulman Hilmican
- Ulutaş Mehmet Eşref
- Underwood Kirk
- Unsworth Richard
- Uprak Tevfik Kivilcim
- Urriza Pablo Vallés
- Usman Muhammad
- Usman Mustapha Ibrahim
- Vaassen Lauretta
- Vaccara Vincenzo La
- Vagena Xanthoula
- Vagge Aldo
- Vailas Michail
- Valadez Andrea Estefania Cueto
- Valadez Tania Abigail Cueto
- Valanci Sofia
- Valdespino Cristina Puentes
- Valeanu Liana
- Valioulis Ioannis
- Valladares Sergio Chávez
- Vallve-Bernal Marc
- Van Acker Jill
- Van Den Eynde Jef
- Van Goor Harry
- Van Vliet Helen
- Van Wyk Naomi Natasha
- Vanni Camilla
- Vas Aurelia
- Vasarhelyi Edward
- Vaschetti Roberto
- Vassiliu Panteleimon
- Vatansever Dogan
- Vatish Jamie
- Vaughan-Shaw Peter G.
- Vaysburg Dennis
- Veglia Antonella
- Velten Markus
- Velázquez Maria Jose Martinez
- Venkatappa Sunil Kumar
- Venketeswaran Meenakshi
- Venskutonis Donatas
- Verbic Milena Senica
- Verdi Daunia
- Vergara-Fernandez Omar
- Verhoeff Kevin
- Veroux Massimiliano
- Verras Georgios-Ioannis
- Verre Luigi
- Vida Lucian
- Vidya Raghavan
- Viglietta Edoardo
- Vijay Vardhini
- Vijgen Guy
- Vilaró Blanca Capdevila
- Villanueva Julio
- Vilz Tim O.
- Vincent Elizabeth
- Vinci Danilo
- Viola Simona
- Violante Tommaso
- Vishnoi Jeewan Ram
- Vissapragada Ravi
- Vivancos Laura Guillamon
- Vives Josep Maria Muñoz
- Vizzielli Giuseppe
- Vohra Lubna
- Vokshi Ismail
- Vosinakis Christos
- Vásquez Javier Alberto Gutiérrez
- Vázquez Gil
- Vázquez Irene Ortega
- Vǎcǎraşu Andrei Bogdan
- Wade Ryckie
- Wafi Omar
- Wagner Gabriela
- Wallis Christopher
- Wanjara Samuel
- Waqar Shahzad Hussain
- Warden Claire
- Warner Christian
- Wasim D.
- Wason Shaun
- Wasserman Isaac
- Watcyn-Jones Tom
- Waterson Ben
- Watson David
- Watson Matthew
- Weber Clemens
- Wheatstone P.
- Wheeler James
- Wheldon Luke
- White Michelle
- White Stuart
- White William
- Wickramasinghe Dakshitha
- Widmer Lukas Werner
- Wiedemann Dominik
- Wiesinger Clemens Georg
- Wijekoon Naveen
- Wijenayake Wasantha
- Wijeyaratne Manuk
- Wijeysundera Duminda
- Wiles Matthew
- Wilkin Richard
- Wilkins Alex
- Wilkins James
- William Tinka George
- Williams Omolara Modupe
- Williams Shekinah
- Windsor John
- Winnand Philipp
- Wittmann Maria
- Wolde Amanuel
- Wolfenden John W. D.
- Wong Benjamin Ngie Xiong
- Wong Enoch
- Wong Evan G.
- Wong George Kwok Chu
- Wong Ho Ying Flora
- Wong Kai Yuen
- Wormald Justin
- Wright Deborah
- Wright Joshua
- Wu Fiona
- Wurm Markus
- Xenaki Sofia
- Yadev Ip
- Yahaya Ahmad Shuib
- Yakubu Mustapha
- Yang Wah
- Yanik Özge
- Yanowsky-Reyes Guillermo
- Yassin Abubaker
- Yates Elizabeth
- Yebes Alvaro
- Yenli Edwin Mwintiereh Ta-Ang
- Yeoh Tien
- Yeung Justin
- Yiallourou Anneza
- Yigit Banu
- Yildirim Asif
- Yim Guang
- Yiu Andrew
- Yonekura Hiroshi
- Yotsov Tsanko
- Younis Muhammad Umar
- Yunus Alif
- Yusefi Hossein
- Zabaleta Jon
- Zabkiewicz Catheriner
- Zaccaria Giulia
- Zacharia Bincy
- Zafar Syed Nabeel
- Zago Mauro
- Zaheen Zakia
- Zahid Zahra
- Zaimis Tilemachos
- Zakaria Andee Dzulkarnaen
- Zambon Martina
- Zamora Lindsey
- Zampogna Biagio
- Zancana Giuseppa
- Zani Augusto
- Zanin Luca
- Zanini Nicola
- Zapardiel Ignacio
- Zapata Carlos Shiraishi
- Zarif Pierre
- Zaránd Attila
- Zehnder Philipp
- Zenger Serkan
- Zenha Horácio
- Zhu Michael Z. L.
- Ziemann Sebastian
- Zimak Danijela Mrazovac
- Zimak Zoran
- Zivkovic Dragana
- Zizzo Maurizio
- Zucker Benjamin
- Zwain Yasir
- Zyskowski Michael
- Ávila Clara Castro
- Älgå Andreas
- Çakici Mehmet Çaǧlar
- Çelik Enes
- Çelik Meryem Nur
- Özçay Necdet
- Şevik Hüsnü
- Šantak Goran
- Šimko Kristián
- Žatecký Jan
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2023
- Field of study
Abstract
Background
Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres.
Methods
This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries.
Results
In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia.
Conclusion
This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries
Cell culture media supplemented with raffinose reproducibly enhances high mannose glycan formation
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/10/2021
- Field of study
Glycosylation plays a pivotal role in pharmacokinetics and protein physiochemical characteristics. In particular, effector functions including antibody-dependent cell-mediated cytotoxicity (ADCC) can be desired, and it has been described that high-mannose species exhibited enhanced ADCC. In this work we present the trisaccharide raffinose as a novel cell culture medium supplement to promote high mannose N-glycans in fed-batch cultures, which is sought after in the development of biosimilars to match the quality profile of the reference medicinal product (RMP) also. Up to six-fold increases of high mannose species were observed with increasing raffinose concentrations in the medium of shaken 96-deepwell plates and shake tubes when culturing two different CHO cell lines in two different media. The findings were confirmed in a pH-, oxygen- and CO2-controlled environment in lab-scale 3.5-L bioreactors. To circumvent detrimental effects on cell growth and productivity at high raffinose concentrations, the media osmolality was adjusted to reach the same value independently of the supplement concentration. Interestingly, raffinose predominantly enhanced mannose 5 glycans, and to a considerably smaller degree, mannose 6. While the underlying mechanism is still not fully understood, minor effects on the nucleotide sugar levels have been observed and transcriptomics analysis revealed that raffinose supplementation altered the expression levels of a number of glycosylation related genes. Among many genes, galactosyltransferase was downregulated and sialyltransferase upregulated. Our results highlight the potential of cell culture medium supplementation to modulate product quality
Bartonella spp. in Bats, Kenya
- Author
- Anderson
- Bennett
- Bernard Agwanda
- Billeter
- Birtles
- Breitschwerdt
- Calisher
- Charles E. Rupprecht
- Chomel
- Concannon
- Daly
- Dehio
- Drexler
- Eremeeva
- Evans
- Ghatak
- Halpin
- Ivan V. Kuzmin
- Kerkhoff
- Kosoy
- Kosoy
- Kosoy
- Kosoy
- Kuzmin
- Kuzmin
- La Scola
- Li
- Loftis
- Michael Kosoy
- Michael Niezgoda
- Reeves
- Reeves
- Richard Franka
- Robert F. Breiman
- Roux
- Tarah Lynch
- Tong
- Towner
- van der Poel
- Wang
- Welch
- Ying Bai
- Publication venue
- Centers for Disease Control and Prevention
- Publication date
- 01/12/2010
- Field of study
We report the presence and diversity of Bartonella spp. in bats of 13 insectivorous and frugivorous species collected from various locations across Kenya. Bartonella isolates were obtained from 23 Eidolon helvum, 22 Rousettus aegyptiacus, 4 Coleura afra, 7 Triaenops persicus, 1 Hipposideros commersoni, and 49 Miniopterus spp. bats. Sequence analysis of the citrate synthase gene from the obtained isolates showed a wide assortment of Bartonella strains. Phylogenetically, isolates clustered in specific host bat species. All isolates from R. aegyptiacus, C. afra, and T. persicus bats clustered in separate monophyletic groups. In contrast, E. helvum and Miniopterus spp. bats harbored strains that clustered in several groups. Further investigation is needed to determine whether these agents are responsible for human illnesses in the region
A protocol to evaluate the impact of involvement of older people with dementia and age-related hearing and/or vision impairment in a multi-site European research study
- Author
- A Grundy
- Charlotte Paterson
- D Gove
- D Milne
- D Tanner
- Elizabeth Hanson
- F Bunn
- F Poland
- Franka Meiland
- G Hubbard
- GJ Acton
- Greg Guest
- I Hellstrom
- J Brett
- J Carpenter
- J Dewing
- J McKeown
- J Miah
- J Ritchie
- J Tooke
- JP Domecq
- K Murphy
- Katherine H O Deane
- L Nygard
- LA Yates
- M Downs
- Michelle O’Reilly
- R Bartlett
- R Cheston
- R Telford
- Rosemary Littlechild
- Rosemary Littlechild
- S Staniszewska
- T Kitwood
- V Braun
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
The Prevalence of Peyronie's Disease in the United States: A Population-Based Study
- Author
- A El-Sakka
- A Tefekli
- Al El-Sakka
- Al El-Sakka
- Anna Perlaky
- CJ Devine Jr
- Dan Glass
- David J. Handelsman
- DB DiBenedetti
- DJ Ralph
- E Pawlowska
- EL Rhoden
- EW Hauck
- F Sommer
- FR Romero
- Franka des Vignes
- HM Nugteren
- J Abernethy
- JP Mulhall
- JP Pryor
- K Shiraishi
- L Vi
- LA Levine
- LM Nyberg Jr
- M Arafa
- Mark Stuntz
- MB Lindsay
- R Tal
- RS Ling
- S Deveci
- S Hindocha
- S Musitelli
- Tassos Kyriakides
- U Schwarzer
- WJ Hellstrom
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
Safety, efficacy and immunogenicity evaluation of the SAG2 oral rabies vaccine in Formosan ferret badgers
- Author
- Ai-Ping Hsu
- AS Huang
- CA Hanlon
- CA Hanlon
- Chia-Chia Chang
- Chun-Hsien Tseng
- Chun-Ta Lin
- CL Schumacher
- DJ Dean
- E Robardet
- EH Follmann
- F Cliquet
- F Cliquet
- F Cliquet
- F Cliquet
- F Cliquet
- F Cliquet
- F Cliquet
- F Lafay
- Florence Cliquet
- Hsiang-Jung Tsai
- HY Weng
- J Bingham
- J Bingham
- J Blancou
- J Zhao
- Jacques Barrat
- JL Dyer
- LA Orciari
- M Artois
- M Lambot
- MA Vigilato
- Marine Wasniewski
- P Mahl
- Paulo Lee Ho
- Philippe Mähl
- R Franka
- R Menezes
- Re-Shang Chen
- RL Hu
- S Hammami
- Shu-Hwae Lee
- WA Webster
- Wen-Jane Tu
- YH Hsu
- Yu-Hua Shih
- ZY Gong
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
DEA Praktikum Köln 23/24
- Author
- Alexa Kämpfe
- Amelie Lessmann
- Amelie Stadtbäumer
- Anna Esser
- Anna Hertges
- Antonia Spohr
- Cara Dühr
- Carolin Häffner
- Carolin-Sophie Bausch
- Charlotte Stierstorfer
- Christoph Stahl
- Clara Felder
- Corinna Hoffschulz
- Cosima Heilmann
- Daniel Alexander
- Eileen Schneider
- Elena Weiß
- Elena Zimmer
- Elisa Steele
- Elisa Weinand
- Emilia Bozzetti
- Emilia Schilken
- Emily Kurth
- Erik Schulz
- Erkam Ilhan
- Eva Adrian
- Fabia Krahforst
- Felix Folgner
- franka Haberbosch
- Gesa Porfetye
- Gina Gerhards
- Giorgio Alagna
- Hannah Klütsch
- Hannah Korst
- Inas Yousef
- Jan Klemens
- Jana Espelage
- Jana Marxer
- Jana Moos
- Jana Nießen
- Jana Oertel
- Jasmin Kühnert
- Jasper Zeno Siol
- Jennifer Handlogten
- Jil Mickeleit
- Johanna Müller
- Johanna Schrader
- Joshua Noah Tewes
- Julia Lampen
- Julius Schueftan
- Julius Simon Herzig
- Katharina Klug
- Kerstin Krieg
- Kim Prox
- Konrad Bach
- Laszlo Hardekopf
- Laura Hense
- Lea Kemalides
- Lea Olbertz
- Lisa Kick
- Lisa Mohr
- Lisa Schmidt
- Magali Raßmann
- Malin Röders
- Manuela Bender
- Maria de la Varga
- Maria Müller
- Marie Josefine Klug
- Marie Lampka
- Martin Leon Schirmer
- Martin Schirmer
- Maximilian Barát
- Maximilian Spöhle
- Melika Karacic
- Natalie Wochnik
- Neele Duna
- Nicole Schwindt
- Noa Rabea Alena Seiler
- Osa-Mudia Otobo
- Patricia Beiten
- Paula Franke
- Pauline Weuffen
- Philip Schmitt
- Pia Rübsamen
- Rabea Balthaus
- Rebecca Franziska Salzmann
- Rebecca Kresimon
- Rike Stegert
- Sarah Fiedler
- Simone Piendl
- Solin Karim
- Sophia Allgeyer
- Sophia Lammertz
- Steffen Filz
- Svenja Rott
- Tabea Moschner
- Tobias Lang
- Tobias Lang
- Truong Giang Dao
- Vera Can
- Yasmina Pirouz
- Publication venue
- 'Center for Open Science'
- Publication date
- 04/12/2023
- Field of study
DAMPs and influenza virus infection in ageing
- Author
- Agrawal
- Ahmed
- Alexandrova
- Allen
- Allen
- Alves Galvao
- Andersson
- Arias
- Aspinall
- Atallah
- Barja
- Barnard
- Baroja-Mazo
- Barrett
- Baskin
- Beli
- Bermejo-Martin
- Bianchi
- Biragyn
- Blasco
- Bode
- Boehmer
- Boon
- Bour-Jordan
- Broggi
- Broz
- Brundage
- Bustin
- Castle
- Cavanagh
- Cerbulo-Vazquez
- Chan
- Chen
- Chung
- Chung
- Chung
- Chung
- Church
- Cicin-Sain
- Cicin-Sain
- Cilloniz
- Coluzzi
- Correia-Melo
- Dassah
- Davalos
- Dawood
- de Jong
- de la Fuente
- de Magalhães
- Decman
- Deng
- Deng
- Derek
- Di Virgilio
- Diebold
- Diebold
- Donowitz
- d’Adda di Fagagna
- Ehrchen
- Enrich
- Feldman
- Finelli
- Fishman
- Flower
- Foell
- Foell
- Franceschi
- Franceschi
- Franceschi
- Fritz
- Fuertes
- Fujino
- Gardella
- Geginat
- Geginat
- George
- Gharibyan
- Ghavami
- Gill
- Ginaldi
- Glezen
- Goldstein
- Goronzy
- Grabowska
- Greenbaum
- Grevers
- Grewal
- Hak
- Hancock
- Haq
- Harris
- Hasegawa
- Hauet-Broere
- Hayflick
- Hedayat
- Heng
- Herbig
- Hernandez-Vargas
- Hewitt
- Hifumi
- Hiratsuka
- Hitchcock
- Holsinger
- Hou
- Hoyaux
- Huang
- Huttunen
- Ichinohe
- Ichinohe
- Ison
- Iwasaki
- Izurieta
- Jackaman
- Jain
- Jefferson
- Jefferson
- Jiang
- Joseph
- Jurk
- Kang
- Kanneganti
- Kaplan
- Kaspar
- Kassam
- Kataoka
- Kawada
- Kawai
- Kawanishi
- Kawasaki
- Kim
- Kirpotina
- Klepser
- Klune
- Kokkola
- Kosai
- Kruk
- Krysko
- Kumar
- Kumar
- Kummer
- Kuribayashi
- Kwon
- Lai
- Lambert
- Lanzer
- LeBouder
- LeBouder
- Lee
- Lee
- Lee
- Lemaitre
- Leukert
- Li
- Li
- Liao
- Liew
- Lina H.K. Lim
- Lindau
- Liu
- Lizarbe
- Lopez-Medrano
- Lotze
- Lund
- Lynch
- Ma
- Ma
- Madureira
- Maines
- Mariathasan
- Matsuyama
- McAuley
- McCarthy
- McCullers
- McCullers
- McDonald
- McElhaney
- McKanna
- Medzhitov
- Messmer
- Moisy
- Mok
- Molinari
- Mora
- Moran
- Moreno
- Murasko
- Murata
- Musiol
- Nagel
- Nalapareddy
- Narasaraju
- Nawa
- Nelson
- Neralla
- Neumann
- Neuzil
- Nikolich-Zugich
- Nikolich-Zugich
- Nogueira-Machado
- Nosaka
- Oikawa
- Olivieri
- Oppenheim
- Otto
- Owen
- Panda
- Passos
- Pawelec
- Pawelec
- Peiris
- Petrilli
- Pettigrew
- Peuscher
- Peuscher
- Pinto
- Ramar Perumal Samy
- Rang Franka
- Ravasi
- Rehwinkel
- Rehwinkel
- Renshaw
- Rescher
- Riberdy
- Rock
- Rodier
- Rothberg
- Rudd
- Réty
- Sakaguchi
- Sakwe
- Salama
- Salminen
- Salomon
- Saurwein-Teissl
- Scaffidi
- Schulz
- Scott
- Seropian
- Shaw
- Shirey
- Simonsen
- Singh
- Singh
- Smithey
- Sohal
- Stout-Delgado
- Streicher
- Strindhall
- Suh
- Swindell
- Swisher
- Swisher
- Szucs
- Takeda
- Takeda
- Takeuchi
- Tang
- Thomas
- Thomas
- Thompson
- Thompson
- Toapanta
- Toschke
- Tsai
- Umeda
- van Attikum
- van Beijnum
- van Lent
- Van Reeth
- Vasto
- Vasto
- Vasto
- Viboud
- Vijaykrishna
- Viláde Muga
- Vogl
- Vogl
- Walker
- Wang
- Wang
- Weng
- Wilkinson
- Wong
- World Health Organization
- World Health Organization (WHO)
- Xi
- Xu
- Xu
- Xue
- Yager
- Yamada
- Yamane
- Yan
- Yang
- Yang
- Yang
- Yang
- Yanga
- Yewdell
- Yin
- Youm
- Yu
- Zheng
- Zhou
- Zhou
- Zibouche
- Zitvogel
- Zou
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
Second asymptomatic carotid surgery trial (ACST-2) : a randomised comparison of carotid artery stenting versus carotid endarterectomy
- Author
- \u160ercl Miroslav
- \u160koloud\uedk David
- \u160tekl\ue1cov\ue1 Anna
- Abd-Allah Foad
- Abdul-Hamiq Ahmed
- Abdulamit Timur
- Accrocca Federico
- Acosta Stefan
- Ahlhelm Frank J
- Aidashova Balzhan
- Akyea-Mensah Joyce
- Albuquerque e Castro Jo\ue3o
- Aleksic Nikola
- Allaire Eric
- Almekhlafi Mohammed A
- Alonso Angelika
- Alves Gon\ue7alo
- Alwis Lanka
- Amatucci Giovanni
- Ambrogi Cesare
- Amis Deborah
- Anderson Dawn
- Andonova Silva
- Andziak Piotr
- Angiletta Domenico
- Angus Jane
- Antonopoulos Constantine N
- Aparici Robles Fernando
- Argentieri Angelo
- Arnold Sebastian
- Ashleigh Ray
- Ashley Simon
- Asokanathan Asaipillai
- Astarci Parla
- Babic Srdan
- Bachvarov Chavdar
- Baht Hardeep
- Bajardi Guido
- Bajoriene Milda
- Baker Lucy
- Bakke S\uf8ren
- Bal Simerpreet
- Ball Stephen
- Balogun Ibrahim
- Barbazza Renzo
- Barber Phillip A
- Barer David
- Bari Vasha
- Barlinn Jessica
- Bartko Daniel
- Barwell James
- Barz\uf3 P\ue1l
- Bastos Gon\ue7alves Frederico
- Bausback Yvonne
- Beard Jonathan
- Becquemin Jean-Pierre
- Belcastro Fernando
- Bellenis Ion
- Belli Anna
- Bellini Dalio Marcelo
- Belyasnik Andrey
- Bene\u161 III Vladim\uedr
- Benevento Domenico
- Beno Peter
- Berekoven B\ue4rbel
- Berg Bengt
- Berger Hermann
- Bergeron Patrice
- Bernardini Giulia
- Berry Clive
- Beyar Rafi
- Bialek Pawel
- Bianchi Paolo
- Bicknell Colin
- Biejat Zbigniew
- Biermaier Bernhard
- Bir\uf3 G\ue1bor
- Birt Angela
- Bj\uf6rses Katarina
- Blackham Kristine
- Blanco Ca\uf1ibano Estrella
- Blanes Orti Paula
- Bodosi Mihaly
- Bombic Martin
- Bonati Leo H
- Bonati Leo H
- Borger Franka
- Bosiers Marc
- Botsios Spiridon
- Br\ue4unlich Sven
- Bradshaw S
- Brandt Kerstin
- Branzan Daniela
- Briley Dennis
- Brountzos Elias
- Brown Andrew
- Brown Ellen
- Brown Ellen
- Brown James
- Brown Pauline
- Brudlo Wojciech
- Bryce Jenny
- Buchvald Pavel
- Bulbulia Richard
- Bulbulia Richard
- Burger Ilse
- Burzotta Francesco
- Butterfield Stephen
- C\uf6ster Andreas
- Callaert Joren
- Campbell Erik
- Campos Jr Walter
- Cannizzaro Alfredo
- Cao Piergiorgio
- Capoccia Laura
- Cappelli Alessandro
- Cardon Jean-Marie
- Carimati Federico
- Casana Renato
- Casella Ivan B
- Caso Valeria
- Catterson Martin
- Cernetti Carlo
- Chamorro \uc1ngel
- Chataway Jeremy
- Chatzinikou Eleni
- Chechulov Pavel
- Chernyavsky Mikhail A
- Cheshire Nicholas
- Chester Johanna
- Chester Johanna
- Chetter Ian
- Chiarandini Stefano
- Chisci Emiliano
- Chlouba Vladim\uedr
- Chrisopoulou Angela
- Cieri Enrico
- Cirelli Silvana
- Cireni Lea
- Civilini Efrem
- Clarke Alison
- Clarke Mike
- Clarke Sandra
- Cleveland Trevor
- Clifton Andrew
- Clifton Andrew
- Cochennec-Paliwoda Fr\ue9d\ue9ric
- Codispoti Francesco Alberto
- Colgan Mary P
- Colic Momcilo
- Colston Amanda
- Coppi Elisabetta
- Coppi Gioacchino
- Corbetta Riccardo
- Cosier Tracy
- Coutts Shelagh B
- Cowie Linda
- Cox Robin
- Cradduck-Bamford Andrea
- Cradduck-Bamford Andrea
- Cras Patrick
- Crawford Susan
- Crinnion Jamie
- Csobay-Nov\ue1k Csaba
- Cuenoud Larissa
- Cura Fernando
- Cvetic Vladimir
- Cvjetko Ivan
- Czepel Wojciech
- Czlonkowska Anna
- D'Angelo Costantino L
- D'Oria Mario
- D'Souza Stephen
- D\uf3sa Edit
- da Silva Erasmo S
- Dabek Pawel
- Darby Chris
- Davey Philip
- Davidovic Lazar
- Davies Paul
- Davis Michelle
- de Arag\ue3o Morais Jos\ue9
- de Borst Gert J
- De Donato Gianmarco
- De Koster Guy
- de Luccia Nelson
- Debus Eike S
- Dei Negri Massimo
- Delle Martin
- Delodovici Maria Luisa
- Deloose Koen
- DeMarco Ester
- Demchuk Andrew M
- DeRango Paola
- Desantis Claudio
- Desgranges Pascal
- Desiron Quentin
- Di Lazzaro Vincenzo
- Dias Nuno
- Dienel Cora
- Dieng Mortalla
- Diepers Michael
- Dix Francis
- Dixit Anand
- Donnelly Mary
- Dormal Pol
- Dorman Paul
- Dowzenko Anatol
- Dratwicki Maciej
- Drelichowski Stanislaw
- Dunlop Paul
- Durairajan Ragunath
- Dutta Dipankar
- Dyker Alexander
- Dzieciuchowicz Lukasz
- Eckstein Hans-Henning
- Eesa Muneer
- Egun Anselm A
- Eldessoki Mohamed H
- Eley Caroline
- Eliot-Jones Bekky
- Emerson Lorraine
- Endo Hidenori
- Endrych Ladislav
- Enevoldson Peter
- Engelhardt Andreas
- Engelter Stefan
- Entz L\ue1szl\uf3
- Esisi Bernard
- Estenssoro Andr\ue9 E V
- Ettles Duncan
- Eugster Thomas
- Ezura Masayuki
- F\ue1k\uf3 Eniko
- F\ufcl\uf6p B\ue9la
- Fadda Gian Franco
- Faggioli Gianluca
- Farchioni Luca
- Farrell Barbara
- Fathers Susan
- Ferrante Angela
- Ferrero Emanuele
- Ferri Michelangelo
- Fiedler Jir\ued
- Flather Marcus
- Flis Vojko
- Fontana Federico
- Ford Gary
- Formgren Johan
- Fornolles Caroline
- Fraedrich Gustav
- Frerker Klaus
- Furui Eisuke
- G\ufcnther Albrecht
- G\ufcrke Lorenz
- G\ufcrke Lorenz
- Gaba Kamran
- Gabriel Marcin
- Gaggiano Andrea
- Gaines Peter
- Galeotti Roberto
- Gamble Ed
- Garc\ueda Dominguez Luis
- Garc\ueda Fresnillo Beatriz
- Garcia Ana C
- Gargiulo Mauro
- Gasbarro Vincenzo
- Gasparini Mladen
- Geenens Mia
- Gemper Janine
- Gensicke Henrik
- George Jim
- Gerber Johannes
- Ghosh Jonathan
- Giannoukas Athanasios
- Giaquinta Alessia
- Gibbs Richard
- Gil Robert
- Gillgren Peter
- Gillies Michelle
- Gissler Hans Martin
- Gizewski Elke
- Golovkova Maria S
- Gordon Vera
- Gotts\ue4ter Anders
- Gough Michael
- Goyal Mayank
- Gr\uf6chenig Ernst
- Grad Anton
- Graham Anne
- Gramizadeh Gita
- Grassi Viviana
- Gray Mo
- Gray Richard
- Gregary Bindu
- Grimaldi Luigi
- Grimonprez Annelies
- Griselli Filippo
- Groden Christoph
- Gruber Ingrid
- Gruber Philipp
- Grunwald Iris
- Grzyska Ulrich
- Guerra Requena Mercedes
- Gunathilagan Gunaratnam
- Guyler Paul
- H\uf6lzer Henryk
- Haase Kathrin
- Haider Syed N
- Halliday Alison
- Halliday Alison
- Halu\u17ean Damir
- Hamady Mohammad
- Hammer Frank
- Hands Linda
- Harbison Joe
- Hardy Diana
- Hargroves David
- Harman Paula
- Hartmann Christian
- Hayter Elizabeth
- Hazel Beth
- Heiling Bianka
- Hemelsoet Dimitri
- Hendriks Jeroen
- Henning Eckstein Hans
- Herrington Will
- Hes Karel
- Heshmat Kassem Hussein
- Hill Michael D
- Hilltout Paula
- Hoffman Aaron
- Holliday Constance
- Holst Jan
- Hoppenbrouwers Mieke
- Hosseini Hassan
- Howard Dominic
- Hrb\ue1c Tom\ue1\u161
- Hudon Mark E
- Hughes Andrea
- Humphreys John
- Hunte Sophy
- Ignatenko Pavel
- Ilijevski Nenad
- Inoue Takashi
- Insall Robert
- Ioannou Nikolaos
- Irsara Sandro
- Isaak Andrej
- Isernia Giacomo
- Iwanowski Wojciech
- Jackson Ralph
- Jahrome Ommid
- Jakeways Matthew
- Jambula Anitha
- James Alex
- Jarl Lotta
- Jedrzejewska Julia
- Jenkins Alison
- Jenkins Michael
- Jochmann Elisabeth
- Jones Deborah
- Jones Sally
- Jonker Leon
- Joseph Thomas
- Joseph Thomas
- Jovanovic Dejana R
- Joviliano Edwaldo E
- Judge Parminder
- Justin Frances
- Juszynski Michal
- K\uf6lbel Tilo
- K\ufchme Tobias
- Kahles Timo
- Kakisis John D
- Kall Torbj\uf6rn B
- Kallmayer Michael
- Kandyba Dmitry
- Kappadath Sreevalsan
- Kappelle Jaap L
- Karathanos Christos
- Karpenko Andrey
- Karram Tony
- Karvouniari Panagiota
- Kasemi Holta
- Kazan Viviane
- Keene Elizabeth
- Keese Michael
- Kelly Christine
- Kelsall Nicci
- Kenney Carol
- Kerner Arthur
- Keunen Rudolf W M
- Khanom Nyma
- Khuoge Christopher
- Kiechl Stefan
- Kimura Naoto
- King Craig
- Kjellin Per
- Kl\uf6tzsch Christof
- Klein Gary
- Klingner Carsten
- Knippenberg Bob
- Knoflach Michael
- Ko\u161t\ue1l Petr
- Kobayashi Adam
- Kobeiter Hicham
- Komakha Boris B
- Kompara Ingrid
- Koncar Igor
- Koncewicz Katarzyna
- Kondo Ryushi
- Konrad Peter
- Kospanov Nursultan
- Koutsias Stylianos
- Kouvelos Georgios
- Kr\ued\u17e Zdenek
- Krasinski Zbigniew
- Kreiser Kornelia
- Krishnamurthy Ramesh
- Kristmundsson Thorarinn
- Krohg-S\uf8rensen Kristen
- Kuker Wilhelm
- Kuliha Martin
- Kulkarni Sachin
- Kundu Ashish
- Kurien Rijo
- Kusuma Daniel
- La Rosa Giuliana
- Labate Carmelo
- Lacey Austin
- Lacroix Val\ue9rie
- Lakshminarayan Raghuram
- Lambert David
- Lambrecht Bart
- Lardenoije Jan W
- Lauricella Antonio
- Lauwers Patrick
- Lay Michael
- Lazarides Miltos
- Lazaris Andreas
- le Conte Steffi
- Le Gallou-Wittenberg Anne
- Lees Tim
- Lenti Massimo
- Lenzer Janin
- Leopold Peter
- Lepidi Sandro
- Lerut Philipe
- Leszczynski Jerzy
- Lewis-Clarke Catherine
- Lindblad Bengt
- Lindert Ralph
- Lindgren Hans
- Lindh Mats
- Liu Bao
- Liu Chang-Wei
- Lo Rob H
- Loganathan Thayalini
- Lonsdale Robbie
- Loos Caroline
- Louw Stephen
- Ludwig Stefan
- Lyrer Philippe
- Lyssenko Roman
- M\ufcller Mandy
- Maccarrone Giuseppe
- MacDonald Sumaira
- Macho Juan
- MacSweeney Shane
- Madgwick Zahra
- Madhavan Prakash
- Madycki Grzegorz
- Maertens de Noordhout Alain
- Mafham Marion
- Majmudar Nikhil
- Malacrida Giovanni
- Malchiodi Giuseppe
- Malek Andrzej
- Malferrari Giovanni
- Malina Martin
- Malloggi Chiara
- Malmendier Danielle
- Malmstedt Jonas
- Mangialardi Nicola
- Mansfield Averil
- Mansour Wassim
- Mantatzis Michalis
- Maras Dimitrios
- Marcucci Giustino
- Mariani Luigi
- Marinazzo Davide
- Marino Mario
- Mart\uednez L\uf3pez Rafael
- Martelli Edoardo
- Marti Regula
- Marzelle Jean
- Masato Maela
- Mascoli Francesco
- Massoz Mireille
- Mastrangelo Giovanni
- Matela Jo\u17ee
- Matsagkas Miltiadis
- Matsumoto Yasushi
- Maurer Marina
- Mayer Thomas
- Mazzaccaro Daniela
- McCafferty Laura
- McCaslin James
- McClelland Marie
- McCollum Charles N
- McConachie Norman
- McManus Jessica
- Mehrzad Ali
- Mele Maria Agnese
- Mendelow David
- Menon Bijoy K
- Menon Nisha
- Meola Giovanni
- Michelagnoli Stefano
- Mihaylova Boby
- Miksic Kazimir
- Milo\u161evic Zoren
- Milotic Franko
- Mirabella Domenico
- Miralles Hern\ue1ndez Manuel
- Mireskandari Maz
- Mitabouana-Kibou Marie
- Mitchell Duncan
- Mitchelson Kim
- Mitha Alim
- Modafferi Alfredo
- Moll Frans L
- Molyneux Andrew
- Monteiro Jos\ue9 A T
- Montelione Nunzio
- Moore Dermot
- Morata Barrado Pilar C
- Moratto Roberto
- Morris Dylan
- Morrish William F
- Morrison Jackie
- Moulakakis Konstantinos G
- Mrdja Bo\u17eidar
- Muela M\ue9ndez Miguel
- Mujagic Edin
- Munday Andrew
- Mussagaliev Daulet
- Mutavd\u17eic Perica
- Myint Min P
- Myrcha Piotr
- N\ue9meth Tam\ue1s
- Naccarato Marcello
- Nahser Hans
- Nair Raj
- Nano Giovanni
- Nawaz Shah
- Nazzal Munier
- Nedeltchev Krassen
- Nemes Bal\ue1zs
- Nessi Franco
- Netuka David
- Neves Celso R B
- Nichol Ian
- Nikolsky Eugenia
- Nitecki Samy
- Nome Terje
- Nor Azlisham M
- Nowicki Miroslaw
- Nyberg Johan
- Nyman Niklas
- O'Brien Imelda
- O'Brien Richard
- O'Connell Janice
- O'Reilly Joanna
- Obach V\uedctor
- Occhiuto Maria Teresa
- Odero Jr Andrea
- Odero Attilio
- Ohrlander Tomas
- Okhuoya Faith
- Oliver Deborah
- Orrico Matteo
- Ostasz Wiktor
- Oszkinis Grzegorz
- Otto Dagmar
- P\ue4rsson H\ue5kan
- P\ufctz Volker
- Pacchioni Andrea
- Pacewski Bartosz
- Padovani Raymond
- Palasciano Giancarlo
- Palermo Sergio
- Palmer Debbie
- Palmiste Veronika
- Palombo Domenico
- Pan Hongchao
- Pan Hongchao
- Paolucci Aldo
- Parati Gianfranco
- Parlani Gian Battista
- Parr Noala
- Parry Andrew
- Parry Chris
- Patil Abhijeet
- Patti Francesco
- Pazdernyik Szil\ue1rd
- Peeters Andr\ue9
- Pegler Suzannah
- Pereira Antony
- Perfumo Maria Cecilia
- Peters Steven
- Petersen Bj\uf6rn
- Peto Richard
- Peto Richard
- Petrov Vesko
- Petrunic Mladen
- Pfeiffer Tomas
- Phair Alison
- Phiri Duke
- Pickworth Sandra
- Pieragalli Daniela
- Piffaretti Gabriele
- Pini Rodolfo
- Piorkowski Christopher
- Pizzirusso Rocco
- Plate Gunnar
- Pniewski Jaroslaw
- Polanski Jerzy
- Poletto Giorgio
- Polydorou Antonios
- Polydorou Victoria
- Pontes Neto Oct\ue1vio M
- Poorthuis Michiel
- Poskitt Keith
- Potter John
- Potts Caroline
- Pozzi Mucelli Fabio
- Pr\uedvara Mojm\uedr
- Prabakaran Raji O
- Praquin Barbara
- Presti Cal\uf3gero
- Proch\ue1zka V\ue1clav
- Proczka Robert
- Psacharopulo Daniele
- Psychogios Marios
- Puddu Giovanni Maria
- Puech-Le\ue3o Pedro
- Pukacki Fryderyk
- Pula Grazia
- Pulli Raffaele
- Punekar Shuja
- Pupo Guglielmo
- Quaretti Pietro
- Qvarfordt Peter
- R\uf3zanski Dorota
- R\uf6nnle Viola
- Raciborski Witold
- Radak \u110orde
- Rahi M Asad
- Rahimi Kazim
- Raj Sonia
- Ralli Styliani
- Ramadurai Gopi
- Ramsey-Williams Vicki
- Rantner Barbara
- Ratusinski Christoph-Maria
- Raudoniitis Aidas
- Reeps Christian
- Regina Guido
- Reif Michal
- Reijnen Michel
- Reimers Bernhard
- Remonda Luca
- Resch Tim
- Rhymes Christopher
- Riambau Vincent
- Richards Sue
- Richter Nadine
- Righini Paolo
- Roberts Aisling
- Robinson Graham
- Robson Rebecca
- Rocca Tiberio
- Rodgers Helen
- Rogers Gill
- Rogers Steven
- Ronchey Sonia
- Rossi Alessandro
- Rothwell Peter
- Roubec Martin
- Rountas Christos
- Rousas Nikolaos
- Rudenko Hannah
- Rusn\ue1k Franti\u161ek
- Ryckborst Karla J
- Rzezak Jaroslaw
- S\uf6hl Leander
- Saad Georges
- Sacc\ue0 Salvatore
- Sachs Tina
- Sagic Dragan
- Samis Greg
- San Rom\ue1n Luis
- Sandercock Peter
- Sargent Tracey
- Sattar Naweed
- Save Supriya
- Savettieri Giovanni
- Sbarigia Enrico
- Scalise Filippo
- Scheinert Dierk
- Schmidt Andrej
- Schmidt Christine
- Schneider Ralph
- Schubert Julia
- Schuiling Wouter
- Schulz Ursula
- Schulze-Hartung Friederike
- Schumacher Natasha
- Schuster Johannes
- Scialabba Matteo
- Scott Paul
- Sekaran Lakshmanan
- Senaratne Jawaharlal
- Seriki Dare
- Serra Ribeiro Mauricio
- Setacci Carlo
- Setacci Francesco
- Sethuraman Sakthivel
- Seweryniak Piotr
- Shanik Gregor
- Shearman Cliff P
- Shimizu Hiroaki
- Siani Andrea
- Sichel Leonildo
- Siddegowda Shivaprasad
- Silani Vincenzo
- Silingardi Roberto
- Simonte Gioele
- Simpson David
- Singh-Ranger Ravi
- Sinha Devesh
- Sirignano Pasqualino
- Sitr\ue2ngulo Jr Cid J
- Ski\uf6ldebrand Claes
- Skjelland Mona
- Skoba Krisztina
- Skorski Maciej
- Sladojevic Milo\u161
- Slim Fiona
- Slowinski Maciej
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- Zimmermann Alexander
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- Zuromskis Tadas
- Publication venue
- Publication date
- 01/01/2021
- Field of study
Background: Among asymptomatic patients with severe carotid artery stenosis but no recent stroke or transient cerebral ischaemia, either carotid artery stenting (CAS) or carotid endarterectomy (CEA) can restore patency and reduce long-term stroke risks. However, from recent national registry data, each option causes about 1% procedural risk of disabling stroke or death. Comparison of their long-term protective effects requires large-scale randomised evidence.
Methods: ACST-2 is an international multicentre randomised trial of CAS versus CEA among asymptomatic patients with severe stenosis thought to require intervention, interpreted with all other relevant trials. Patients were eligible if they had severe unilateral or bilateral carotid artery stenosis and both doctor and patient agreed that a carotid procedure should be undertaken, but they were substantially uncertain which one to choose. Patients were randomly allocated to CAS or CEA and followed up at 1 month and then annually, for a mean 5 years. Procedural events were those within 30 days of the intervention. Intention-to-treat analyses are provided. Analyses including procedural hazards use tabular methods. Analyses and meta-analyses of non-procedural strokes use Kaplan-Meier and log-rank methods. The trial is registered with the ISRCTN registry, ISRCTN21144362.
Findings: Between Jan 15, 2008, and Dec 31, 2020, 3625 patients in 130 centres were randomly allocated, 1811 to CAS and 1814 to CEA, with good compliance, good medical therapy and a mean 5 years of follow-up. Overall, 1% had disabling stroke or death procedurally (15 allocated to CAS and 18 to CEA) and 2% had non-disabling procedural stroke (48 allocated to CAS and 29 to CEA). Kaplan-Meier estimates of 5-year non-procedural stroke were 2·5% in each group for fatal or disabling stroke, and 5·3% with CAS versus 4·5% with CEA for any stroke (rate ratio [RR] 1·16, 95% CI 0·86-1·57; p=0·33). Combining RRs for any non-procedural stroke in all CAS versus CEA trials, the RR was similar in symptomatic and asymptomatic patients (overall RR 1·11, 95% CI 0·91-1·32; p=0·21).
Interpretation: Serious complications are similarly uncommon after competent CAS and CEA, and the long-term effects of these two carotid artery procedures on fatal or disabling stroke are comparable