1,240 research outputs found
Rotor performance characteristics from an aeroacoustic helicopter wind-tunnel test program
An investigation of helicopter rotor noise at model scale was conducted in the Langley 4 by 7 meter tunnel. The program described was the first of a planned three-phase project whose purpose was to examine the characteristic noise mechanism involved in main rotor/tail rotor interaction noise. This first phase was conducted with a main rotor only, in order to identify the characteristic noise generated by only the main rotor. The aerodynamic operating conditions of the rotor system were defined during the test. The acoustic data were properly referenced
Preliminary rotor wake measurements with a laser velocimeter
A laser velocimeter (LV) was used to determine rotor wake characteristics. The effect of various fuselage widths and rotor-fuselage spacings on time averaged and detailed time dependent rotor wake velocity characteristics was defined. Definition of time dependent velocity characteristics was attempted with the LV by associating a rotor azimuth position with each velocity measurement. Results were discouraging in that no apparent time dependent velocity characteristics could be discerned from the LV measurements. Since the LV is a relatively new instrument in the rotor wake measurement field, the cause of this lack of periodicity is as important as the basic research objectives. An attempt was made to identify the problem by simulated acquisition of LV-type data for a predicted rotor wake velocity time history. Power spectral density and autocorrelation function estimation techniques were used to substantiate the conclusion that the primary cause of the lack of time dependent velocity characteristics was the nonstationary flow condition generated by the periodic turbulence level that currently exists in the open throat configuration of the wind tunnel
A laser velocimeter flow survey above a stalled wing
A laser velocimeter operating in the backscatter mode was used to survey the flow about a stalled wing installed in the Langley V/STOL tunnel. Mean velocities and magnitudes of velocity fluctuations were calculated from measurements of two orthogonal components of velocity. Free shear mixing layers above and below a large separated flow region were defined. Velocity power spectra were calculated at two points in the flow field. The flow-field survey was carried out about a rectangular aspect-ratio-8 wing with an airfoil section. The wing angle of attack was 19.4 deg, the Mach number was 0.148, and the nominal Reynolds number was 1 x 1 million
Correlation of laser velocimeter measurements over a wing with results of two prediction techniques
The flow field at the center line of an unswept wing with an aspect ratio of eight was determined using a two dimensional viscous flow prediction technique for the flow field calculation, and a three dimensional potential flow panel method to evaluate the degree of two dimensionality achieved at the wing center line. The analysis was made to provide an acceptable reference for comparison with velocity measurements obtained from a fringe type laser velocimeter optics systems operating in the backscatter mode in the Langley V/STOL tunnel. Good agreement between laser velocimeter measurements and theoretical results indicate that both methods provide a true representation of the velocity field about the wing at angles of attack of 0.6 and 4.75 deg
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Search for the standard model production of a single top quark in association with a Z0 boson using machine learning techniques
This thesis was submitted for the award of Doctor of Philosophy and was awarded by Brunel University London.This thesis presents a search for the production of a single top quark in association with a Z0 boson in the dileptonic decay channel as predicted by the Standard Model. The search uses 77.8 fbâ1 of data from â = 13 TeV protonâ proton collisions collected by the Compact Muon Solenoid experiment at the Large Hadron Collider during the 2016â2017 data-taking period. The search identified events containing a Z0 boson decay by requiring two opposite-sign same-flavour electrons or muons in the final state with invariant mass compatible with the nominal Z0 boson mass. Products of the top quark decay were identified using techniques developed to identify jets originating from bottom quarks and searching for a jet pair with invariant mass compatible with the W± boson mass. Machine learning techniques were used to further discriminate the signal process from background events. A study was carried out, comparing the performance of boosted decision trees with hyperparameters optimised using a Gaussian process and multi-layer perceptrons on this problem. The boosted decision trees were found to outperform the multi-layer perceptrons. A signal strength of Ì = 6.52+2.30 â2.05 was observed, where Ì = 1.0 corresponds to the Standard Model expectation. The corresponding observed (expected) significance is 3.12 (0.48).Science and Technologies Facilities Counci
Delayed gastric emptying and reduced postprandial small bowel water content of equicaloric whole meal bread versus rice meals in healthy subjects: novel MRI insights
BACKGROUND/OBJECTIVES: Postprandial bloating is a common symptom in patients with functional gastrointestinal (GI) diseases. Whole meal bread (WMB) often aggravates such symptoms though the mechanisms are unclear. We used magnetic resonance imaging (MRI) to monitor the intragastric fate of a WMB meal (11% bran) compared to a rice pudding (RP) meal.
SUBJECTS/METHODS: 12 healthy volunteers completed this randomised crossover study. They fasted overnight and after an initial MRI scan consumed a glass of orange juice with a 2267 kJ WMB or an equicaloric RP meal. Subjects underwent serial MRI scans every 45 min up to 270 min to assess gastric volumes and small bowel water content and completed a GI symptom questionnaire.
RESULTS: The MRI intragastric appearance of the two meals was markedly different. The WMB meal formed a homogeneous dark bolus with brighter liquid signal surrounding it. The RP meal separated into an upper, liquid layer and a lower particulate layer allowing more rapid emptying of the liquid compared to solid phase (sieving). The WMB meal had longer gastric half emptying times (132±8 min) compared to the RP meal (104±7 min), P<0.008. The WMB meal was associated with markedly reduced MRI-visible small bowel free mobile water content compared to the RP meal, P<0.0001.
CONCLUSIONS: WMB bread forms a homogeneous bolus in the stomach which inhibits gastric sieving and hence empties slower than the equicaloric rice meal. These properties may explain why wheat causes postprandial bloating and could be exploited to design foods which prolong satiation
Laser velocimeter survey about a NACA 0012 wing at low angles of attack
An investigation was conducted in the Langley V/STOL tunnel with a laser velocimeter to obtain measurements of airflow velocities about a wing at low angles of attack. The applicability of the laser velocimeter technique for this purpose in the V/STOL tunnel was demonstrated in this investigation with measurement precision bias calculated at -1.33 percent to 0.91 percent and a random uncertainty calculated at + or - 0.47 percent. Free stream measurements were obtained with this device and compared with velocity calculations from pitot static probe data taken near the laser velocimeter measurement location. The two measurements were in agreement to within 1 percent. Velocity measurement results about the centerline at 0.6 degrees angle of attack were typically those expected. At 4.75 degrees, the velocity measurements indicated that a short laminar separation bubble existed near the leading edge with an oscillating shear layer
Analysis of model rotor blade pressures during parallel interaction with twin vortices
This paper presents and provides analysis of unsteady surface pressures measured on a model rotor blade as the blade experienced near parallel blade vortex interaction with a twin vortex system. To provide a basis for analysis, the vortex system was characterized by hot-wire measurements made in the interaction plane but in the absence of the rotor. The unsteady pressure response resulting from a single vortex interaction is then presented to provide a frame of reference for the twin vortex results. A series of twin vortex interaction cases are then presented and analyzed. It is shown that the unsteady blade pressures and forces are very sensitive to the inclination angle and separation distance of the vortex pair. When the vortex cores lie almost parallel to the blade chord, the interaction is characterized by a two-stage response associated with the sequential passage of the two cores. Conversely, when the cores lie on a plane that is almost perpendicular to the blade chord, the response is similar to that of a single vortex interaction. In all cases, the normal force response is consistent with the distribution of vertical velocity in the flow field of the vortex system. The pitching moment response, on the other hand, depends on the localized suction associated with the vortex cores as they traverse the blade chord
Exploratory randomized double-blind placebo controlled trial of botulinum therapy on grasp release after Stroke (PrOMBiS)
Background. OnabotulinumtoxinA injections improve upper-limb spasticity after stroke, but their effect on arm function remains uncertain. Objective. To determine whether a single treatment with onabotulinumtoxinA injections combined with upper-limb physiotherapy improves grasp release compared with physiotherapy alone after stroke. Methods. A total of 28 patients, at least 1 month poststroke, were randomized to receive either onabotulinumtoxinA or placebo injections to the affected upper limb followed by standardized upper-limb physiotherapy (10 sessions over 4 weeks). The primary outcome was time to release grasp during a functionally relevant standardized task. Secondary outcomes included measures of wrist and finger spasticity and strength using a customized servomotor, clinical assessments of stiffness (modified Ashworth Scale), arm function (Action Research Arm Test [ARAT], Nine Hole Peg Test), arm use (Arm Measure of Activity), Goal Attainment Scale, and quality of life (EQ5D). Results. There was no significant difference between treatment groups in grasp release time 5 weeks post injection (placebo median = 3.0 s, treatment median = 2.0 s; t(24) = 1.20; P = .24; treatment effect = â0.44, 95% CI = â1.19 to 0.31). None of the secondary measures passed significance after correcting for multiple comparisons. Both groups achieved their treatment goals (placebo = 65%; treatment = 71%), and made improvements on the ARAT (placebo +3, treatment +5) and in active wrist extension (placebo +9°, treatment +11°). Conclusions. In this group of stroke patients with mild to moderate spastic hemiparesis, a single treatment with onabotulinumtoxinA did not augment the improvements seen in grasp release time after a standardized upper-limb physiotherapy program
Benefits of polidocanol endovenous microfoam (VarithenaÂź) compared with physician-compounded foams
Objective: To compare foam bubble size and bubble size distribution, stability, and degradation rate of commercially
available polidocanol endovenous microfoam (Varithena) and physician-compounded foams using a number of laboratory tests.
Methods: Foam properties of polidocanol endovenous microfoam and physician-compounded foams were measured
and compared using a glass-plate method and a Sympatec QICPIC image analysis method to measure bubble size and
bubble size distribution, TurbiscanTM LAB for foam half time and drainage and a novel biomimetic vein model to measure
foam stability. Physician-compounded foams composed of polidocanol and room air, CO2, or mixtures of oxygen and
carbon dioxide (O2:CO2) were generated by different methods.
Results: Polidocanol endovenous microfoam was found to have a narrow bubble size distribution with no large
(>500 mm) bubbles. Physician-compounded foams made with the Tessari method had broader bubble size distribution
and large bubbles, which have an impact on foam stability. Polidocanol endovenous microfoam had a lower degradation
rate than any physician-compounded foams, including foams made using room air (p < 0.035). The same result was
obtained at different liquid to gas ratios (1:4 and 1:7) for physician-compounded foams. In all tests performed, CO2 foams
were the least stable and different O2:CO2 mixtures had intermediate performance. In the biomimetic vein model,
polidocanol endovenous microfoam had the slowest degradation rate and longest calculated dwell time, which represents the length of time the foam is in contact with the vein, almost twice that of physician-compounded foams using
room air and eight times better than physician-compounded foams prepared using equivalent gas mixes.
Conclusion: Bubble size, bubble size distribution and stability of various sclerosing foam formulations show that
polidocanol endovenous microfoam results in better overall performance compared with physician-compounded
foams. Polidocanol endovenous microfoam offers better stability and cohesive properties in a biomimetic vein model
compared to physician-compounded foams. Polidocanol endovenous microfoam, which is indicated in the United States
for treatment of great saphenous vein system incompetence, provides clinicians with a consistent product with enhanced
handling propertie
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