Paleoecological Significance of Mummified Remains of Pleistocene Horses from the North Slope of the Brooks Range, Alaska

Radiocarbon dates from horse fossils found on the North Slope of Alaska show that horses did live there during the last peak glacial (Duvanny Yar Interval, Marine Isotope Stage 2). Some previous paleoecological studies have assumed the region's climate was too extreme for large mammals during the Duvanny Yar. Hoof structure suggests the Pleistocene horses survived on winter range characterized by low snowfall and/or snow removal by wind. Hoof growth rate suggests a substantial dietary volume of exposed dead grass during winter; hoof wear pattern indicates the horses were able to remain relatively sedentary, requiring neither long-distance winter migration nor constant digging through snow for food. Bones with mummified soft tissue may have been buried and preserved by wind-drifted eolian silt.

Pleistocene, Holocene and Recent Bird Gastroliths from Interior Alaska

Describes and discusses the origin of polished and rounded grains of quartz, secondary quartz, and chert from (probably) Holocene loess of Easter Egg Hill near Livengood townsite, peat on the Nenana Road, and redeposited Wisconsin loess from the Eva Creek Mine and Ready Bullion Creek Mine at 64 51 N, 148 02 W. The association of these grains with dull, angular grains of the same materials rules out soil or solifluction abrasion in place. Gizzard-bearing birds such as ptarmigan and grouse in Alaska produce glossy polish on their gizzard stones (gastroliths) comparable to that of the Pleistocene and Holocene gastroliths; the polish and roundness of the stones in living birds are more pronounced in late winter. Because the modal size classes of ancient and Recent polished gastroliths do not coincide, some of the ancient gastroliths are believed to have been produced by birds not now living in interior Alaska.Gastrolithes d'oiseaux pléistocènes, holocènes et récents de l'Alaska intérieur. On trouve dans le loess et la tourbe de l'Alaska intérieur des grains polis et arrondis de quartz, de quartz secondaire et de chert. Le diamètre intermédiaire de ces grains se situe entre 35 et 0.07 mm, les plus abondants mesurant 0.07 mm, de 2 à 4 mm et peut-être, de 10 à 20 mm. Le poli de ces grains est le produit de l'abrasion dans des gésiers d'oiseaux. Les oiseaux à gésier qui vivent aujourd'hui dans l'Alaska intérieur produisent sur leurs gastrolithes un fini poli comparable à celui des gastrolithes des dépôts holocènes et pléistocènes. Sur les gastrolithes d'oiseaux récents, le poli et l'arrondi varient directement, atteignant un maximum pour les oiseaux vivants à la fin de l'hiver. On peut croire que certaines gastrolithes polies de l'Holocène et du Pléistocène ont été produites par des oiseaux qui ne vivent plus aujourd'hui dans l'Alaska intérieur, car les classes dimensionnelles de ces gastrolithes anciennes ne coïncident plus avec celles des gastrolithes des oiseaux d'aujourd'hui

NACHOS, a CubeSat-Based High-Resolution UV-Visible Hyperspectral Imager for Remote Sensing of Trace Gases: System Overview, Science Objectives, and Preliminary Results

The Nano-satellite Atmospheric Chemistry Hyperspectral Observation System (NACHOS) is a high-throughput (f/2.9), high spectral resolution (1.3 nm optical, 0.57 nm sampling) hyperspectral imager covering the 300-500 nm spectral region with 350 spectral bands. The combined 1.5U instrument payload and 1.5U spacecraft bus comprise a 3U CubeSat. Spectroscopically similar to NASA’s Ozone Monitoring Instrument (OMI), which provides wide-field coverage at ~20 km spatial resolution, NACHOS offers complementary targeted measurements at far higher spatial resolution of ~0.4 km/pixel from 500 km altitude over its 15 ̊ across-track field of view. NACHOS incorporates highly streamlined onboard gas-retrieval algorithms, alleviating the need to routinely downlink massive hyperspectral data cubes. This paper discusses the instrument design, requirements leading to it, preliminary results, and science goals, including monitoring NO2 as a proxy for anthropogenic greenhouse gases, low-level degassing of SO2 and halogen oxides at pre-eruptive volcanoes, and formaldehyde from wildfires. Aiming for an eventual many-satellite constellation providing both high spatial resolution and frequent target revisits, the current NACHOS project is launching two CubeSats, the first already launched to the International Space Station aboard the NG-17 Cygnus vehicle on February 19, 2022 and awaiting deployment to its final orbit in June, and the second launching June 29, 2022

Cause of Death and Predictors of All-Cause Mortality in Anticoagulated Patients With Nonvalvular Atrial Fibrillation : Data From ROCKET AF

M. Kaste on työryhmän ROCKET AF Steering Comm jäsen.Background-Atrial fibrillation is associated with higher mortality. Identification of causes of death and contemporary risk factors for all-cause mortality may guide interventions. Methods and Results-In the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF) study, patients with nonvalvular atrial fibrillation were randomized to rivaroxaban or dose-adjusted warfarin. Cox proportional hazards regression with backward elimination identified factors at randomization that were independently associated with all-cause mortality in the 14 171 participants in the intention-to-treat population. The median age was 73 years, and the mean CHADS(2) score was 3.5. Over 1.9 years of median follow-up, 1214 (8.6%) patients died. Kaplan-Meier mortality rates were 4.2% at 1 year and 8.9% at 2 years. The majority of classified deaths (1081) were cardiovascular (72%), whereas only 6% were nonhemorrhagic stroke or systemic embolism. No significant difference in all-cause mortality was observed between the rivaroxaban and warfarin arms (P=0.15). Heart failure (hazard ratio 1.51, 95% CI 1.33-1.70, P= 75 years (hazard ratio 1.69, 95% CI 1.51-1.90, P Conclusions-In a large population of patients anticoagulated for nonvalvular atrial fibrillation, approximate to 7 in 10 deaths were cardiovascular, whereasPeer reviewe

Topological cell clustering in the ATLAS calorimeters and its performance in LHC Run 1

The reconstruction of the signal from hadrons and jets emerging from the proton–proton collisions at the Large Hadron Collider (LHC) and entering the ATLAS calorimeters is based on a three-dimensional topological clustering of individual calorimeter cell signals. The cluster formation follows cell signal-significance patterns generated by electromagnetic and hadronic showers. In this, the clustering algorithm implicitly performs a topological noise suppression by removing cells with insignificant signals which are not in close proximity to cells with significant signals. The resulting topological cell clusters have shape and location information, which is exploited to apply a local energy calibration and corrections depending on the nature of the cluster. Topological cell clustering is established as a well-performing calorimeter signal definition for jet and missing transverse momentum reconstruction in ATLAS

The genetic architecture of the human cerebral cortex

The cerebral cortex underlies our complex cognitive capabilities, yet little is known about the specific genetic loci that influence human cortical structure. To identify genetic variants that affect cortical structure, we conducted a genome-wide association meta-analysis of brain magnetic resonance imaging data from 51,665 individuals. We analyzed the surface area and average thickness of the whole cortex and 34 regions with known functional specializations. We identified 199 significant loci and found significant enrichment for loci influencing total surface area within regulatory elements that are active during prenatal cortical development, supporting the radial unit hypothesis. Loci that affect regional surface area cluster near genes in Wnt signaling pathways, which influence progenitor expansion and areal identity. Variation in cortical structure is genetically correlated with cognitive function, Parkinson's disease, insomnia, depression, neuroticism, and attention deficit hyperactivity disorder

Body hot spots : the anatomy of human social organs and behavior

xii, 240 p.; 21 cm