Características Antropométricas, Composición corporal y Somatotipo en Jugadores de Rugby Sevens

Introduction: The objective of this study was to analyze the anthropometric characteristics of body composition and somatotype in senior rugby seven players. The sample was 21 players (age 24.2 ± 5.1 years, weight 81.0 ±14.7 kg, height 175.5 ±4.8 cm) belonging to a departmental team. Methods: 22 anthropometric measurements were taken (two basic, eight skinfolds, three diameters and seven perimeters); Anthropometric characteristics, body composition, and somatotype were determined. A descriptive statistical analysis was performed in SPSS, and the normality of the data was checked using the Shapiro-Wilk test. Significance level p>0.05. Results: Among the results found are muscle mass 41.2 ± 5.4 kg, bone mass 11.4 ± 1.4 kg and fat percentage using the Faulkner formulas 13.9 ± 2.2%, Carter 10.4 ± 2.1% and Yuhazs 15.1 ± 3.1%. Regarding the somatotype reported, it is endomesomorphic. Conclusion: there is no defined profile regarding the muscle or fat component, nor a consensus on how to quantify these components.Introducción: El objetivo de este estudio fue analizar las características antropométricas de composición corporal y somatotipo en jugadores de rugby sevens categoría mayores. La muestra fue de 21 jugadores (edad 24.2 ± 5.1 años, peso de 81.0 ±14,7 kg, talla 175.5 ±4.8 cm) pertenecientes a una selección departamental. Métodos: Se tomaron 22 medidas antropométricas (dos básicas, ocho pliegues, tres diámetros y siete perímetros); se determinaron las características antropométricas, composición corporal y somatotipo. Se hizo un análisis estadístico descriptivo en SPSS, se comprobó la normalidad de los datos por medio de la prueba Shapiro-Wilk. Nivel de significancia p>0,05. Resultados: Dentro de los resultados hallados está la masa muscular 41.2 ± 5.4 kg, masa ósea 11.4 ± 1.4 kg y porcentaje de grasa mediante las fórmulas de Faulkner 13.9 ± 2.2 %, Carter 10.4 ± 2.1 % y Yuhasz 15.1 ± 3.1 %. En cuanto al somatotipo reportado es endomesomorfo. Conclusión: En conclusión, no existe un perfil definido frente al componente muscular o graso, ni tampoco un consenso de como cuantificar dichos componentes

Azimuthal anisotropy of charged jet production in root s(NN)=2.76 TeV Pb-Pb collisions

We present measurements of the azimuthal dependence of charged jet production in central and semi-central root s(NN) = 2.76 TeV Pb-Pb collisions with respect to the second harmonic event plane, quantified as nu(ch)(2) (jet). Jet finding is performed employing the anti-k(T) algorithm with a resolution parameter R = 0.2 using charged tracks from the ALICE tracking system. The contribution of the azimuthal anisotropy of the underlying event is taken into account event-by-event. The remaining (statistical) region-to-region fluctuations are removed on an ensemble basis by unfolding the jet spectra for different event plane orientations independently. Significant non-zero nu(ch)(2) (jet) is observed in semi-central collisions (30-50% centrality) for 20 <p(T)(ch) (jet) <90 GeV/c. The azimuthal dependence of the charged jet production is similar to the dependence observed for jets comprising both charged and neutral fragments, and compatible with measurements of the nu(2) of single charged particles at high p(T). Good agreement between the data and predictions from JEWEL, an event generator simulating parton shower evolution in the presence of a dense QCD medium, is found in semi-central collisions. (C) 2015 CERN for the benefit of the ALICE Collaboration. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).Peer reviewe

Pseudorapidity and transverse-momentum distributions of charged particles in proton-proton collisions at root s=13 TeV

The pseudorapidity (eta) and transverse-momentum (p(T)) distributions of charged particles produced in proton-proton collisions are measured at the centre-of-mass energy root s = 13 TeV. The pseudorapidity distribution in vertical bar eta vertical bar <1.8 is reported for inelastic events and for events with at least one charged particle in vertical bar eta vertical bar <1. The pseudorapidity density of charged particles produced in the pseudorapidity region vertical bar eta vertical bar <0.5 is 5.31 +/- 0.18 and 6.46 +/- 0.19 for the two event classes, respectively. The transverse-momentum distribution of charged particles is measured in the range 0.15 <p(T) <20 GeV/c and vertical bar eta vertical bar <0.8 for events with at least one charged particle in vertical bar eta vertical bar <1. The evolution of the transverse momentum spectra of charged particles is also investigated as a function of event multiplicity. The results are compared with calculations from PYTHIA and EPOS Monte Carlo generators. (C) 2015 CERN for the benefit of the ALICE Collaboration. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).Peer reviewe

Stroke genetics informs drug discovery and risk prediction across ancestries

Previous genome-wide association studies (GWASs) of stroke — the second leading cause of death worldwide — were conducted predominantly in populations of European ancestry1,2. Here, in cross-ancestry GWAS meta-analyses of 110,182 patients who have had a stroke (five ancestries, 33% non-European) and 1,503,898 control individuals, we identify association signals for stroke and its subtypes at 89 (61 new) independent loci: 60 in primary inverse-variance-weighted analyses and 29 in secondary meta-regression and multitrait analyses. On the basis of internal cross-ancestry validation and an independent follow-up in 89,084 additional cases of stroke (30% non-European) and 1,013,843 control individuals, 87% of the primary stroke risk loci and 60% of the secondary stroke risk loci were replicated (P < 0.05). Effect sizes were highly correlated across ancestries. Cross-ancestry fine-mapping, in silico mutagenesis analysis3, and transcriptome-wide and proteome-wide association analyses revealed putative causal genes (such as SH3PXD2A and FURIN) and variants (such as at GRK5 and NOS3). Using a three-pronged approach4, we provide genetic evidence for putative drug effects, highlighting F11, KLKB1, PROC, GP1BA, LAMC2 and VCAM1 as possible targets, with drugs already under investigation for stroke for F11 and PROC. A polygenic score integrating cross-ancestry and ancestry-specific stroke GWASs with vascular-risk factor GWASs (integrative polygenic scores) strongly predicted ischaemic stroke in populations of European, East Asian and African ancestry5. Stroke genetic risk scores were predictive of ischaemic stroke independent of clinical risk factors in 52,600 clinical-trial participants with cardiometabolic disease. Our results provide insights to inform biology, reveal potential drug targets and derive genetic risk prediction tools across ancestries

Evaluation of appendicitis risk prediction models in adults with suspected appendicitis

Background Appendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. The aim of this study was to determine whether existing risk prediction models can reliably identify patients presenting to hospital in the UK with acute right iliac fossa (RIF) pain who are at low risk of appendicitis. Methods A systematic search was completed to identify all existing appendicitis risk prediction models. Models were validated using UK data from an international prospective cohort study that captured consecutive patients aged 16–45 years presenting to hospital with acute RIF in March to June 2017. The main outcome was best achievable model specificity (proportion of patients who did not have appendicitis correctly classified as low risk) whilst maintaining a failure rate below 5 per cent (proportion of patients identified as low risk who actually had appendicitis). Results Some 5345 patients across 154 UK hospitals were identified, of which two‐thirds (3613 of 5345, 67·6 per cent) were women. Women were more than twice as likely to undergo surgery with removal of a histologically normal appendix (272 of 964, 28·2 per cent) than men (120 of 993, 12·1 per cent) (relative risk 2·33, 95 per cent c.i. 1·92 to 2·84; P < 0·001). Of 15 validated risk prediction models, the Adult Appendicitis Score performed best (cut‐off score 8 or less, specificity 63·1 per cent, failure rate 3·7 per cent). The Appendicitis Inflammatory Response Score performed best for men (cut‐off score 2 or less, specificity 24·7 per cent, failure rate 2·4 per cent). Conclusion Women in the UK had a disproportionate risk of admission without surgical intervention and had high rates of normal appendicectomy. Risk prediction models to support shared decision‐making by identifying adults in the UK at low risk of appendicitis were identified

Wear and Grip Loss Evaluation of High Chromium Welding Deposits Applied on Sugar Cane Rolls1

Wear on sugar cane rolls is an expensive maintenance problem for the sugar cane industry. Wear produces loss of sucrose extraction and loss of grip of the roll on the bagasse. This paper presents the evaluation of wear and loss of grip of hypoeutectic and hypereutectic high chromium welding deposits applied on ASTM A-36 steel and gray cast iron. A modified ASTM G-65 standard test was used. Wear was produced by the abrasive action of wet bagasse with three levels of mineral extraneous matter. Silica grains with sizes in the range of 0.212-0.300 mm (AFS 50/70) were used as mineral extraneous matter. Grip was evaluated by measuring the torque on the power transmission shaft that moves the specimens. Worn surfaces were characterized by using scanning electron microscopy. Wear was found to increase proportionally related to the mineral extraneous matter content. Geometric changes of the weld deposits related to wear caused grip loss. For low mineral extraneous matter level, wear resistance of carbon steel was greater than that of gray cast iron; whereas the opposite was found for high mineral extraneous matter level.

Wear and Grip Loss Evaluation of High Chromium Welding Deposits Applied on Sugar Cane Rolls1

Wear on sugar cane rolls is an expensive maintenance problem for the sugar cane industry. Wear produces loss of sucrose extraction and loss of grip of the roll on the bagasse. This paper presents the evaluation of wear and loss of grip of hypoeutectic and hypereutectic high chromium welding deposits applied on ASTM A-36 steel and gray cast iron. A modified ASTM G-65 standard test was used. Wear was produced by the abrasive action of wet bagasse with three levels of mineral extraneous matter. Silica grains with sizes in the range of 0.212-0.300 mm (AFS 50/70) were used as mineral extraneous matter. Grip was evaluated by measuring the torque on the power transmission shaft that moves the specimens. Worn surfaces were characterized by using scanning electron microscopy. Wear was found to increase proportionally related to the mineral extraneous matter content. Geometric changes of the weld deposits related to wear caused grip loss. For low mineral extraneous matter level, wear resistance of carbon steel was greater than that of gray cast iron; whereas the opposite was found for high mineral extraneous matter level.

Use of failure-to-rescue after emergency surgery as a dynamic indicator of hospital resilience during the COVID-19 pandemic. A multicenter retrospective propensity score-matched cohort study

10.1016/j.ijsu.2022.106890INTERNATIONAL JOURNAL OF SURGERY106complete

生産增加と貨幣需要

We report on two-particle charge-dependent cor- relations in pp, p\u2013Pb, and Pb\u2013Pb collisions as a function of the pseudorapidity and azimuthal angle difference, \u3b7 and \u3c6 respectively. These correlations are studied using the balance function that probes the charge creation time and the develop- ment of collectivity in the produced system. The dependence of the balance function on the event multiplicity as well as on the trigger and associated particle transverse momentum ( pT ) in pp, p\u2013Pb, and Pb\u2013Pb collisions at 1asNN = 7, 5.02, and 2.76 TeV, respectively, are presented. In the low transverse momentum region, for 0.2 < pT < 2.0 GeV/c, the balance function becomes narrower in both \u3b7 and \u3c6 directions in all three systems for events with higher multiplicity. The experimental findings favor models that either incorporate some collective behavior (e.g. AMPT) or different mecha- nisms that lead to effects that resemble collective behavior (e.g. PYTHIA8 with color reconnection). For higher values of transverse momenta the balance function becomes even narrower but exhibits no multiplicity dependence, indicating that the observed narrowing with increasing multiplicity at low pT is a feature of bulk particle production

Association between administration of IL-6 antagonists and mortality among patients hospitalized for COVID-19 : a meta-analysis

IMPORTANCE Clinical trials assessing the efficacy of IL-6 antagonists in patients hospitalized for COVID-19 have variously reported benefit, no effect, and harm. OBJECTIVE To estimate the association between administration of IL-6 antagonists compared with usual care or placebo and 28-day all-cause mortality and other outcomes. DATA SOURCES Trials were identified through systematic searches of electronic databases between October 2020 and January 2021. Searches were not restricted by trial status or language. Additional trials were identified through contact with experts. STUDY SELECTION Eligible trials randomly assigned patients hospitalized for COVID-19 to a group in whom IL-6 antagonists were administered and to a group in whom neither IL-6 antagonists nor any other immunomodulators except corticosteroids were administered. Among 72 potentially eligible trials, 27 (37.5%) met study selection criteria. DATA EXTRACTION AND SYNTHESIS In this prospectivemeta-analysis, risk of biaswas assessed using the Cochrane Risk of Bias Assessment Tool. Inconsistency among trial results was assessed using the I-2 statistic. The primary analysis was an inverse variance-weighted fixed-effects meta-analysis of odds ratios (ORs) for 28-day all-cause mortality. MAIN OUTCOMES AND MEASURES The primary outcome measurewas all-cause mortality at 28 days after randomization. There were 9 secondary outcomes including progression to invasive mechanical ventilation or death and risk of secondary infection by 28 days. RESULTS A total of 10 930 patients (median age, 61 years [range of medians, 52-68 years]; 3560 [33%] were women) participating in 27 trials were included. By 28 days, there were 1407 deaths among 6449 patients randomized to IL-6 antagonists and 1158 deaths among 4481 patients randomized to usual care or placebo (summary OR, 0.86 [95% CI, 0.79-0.95]; P =.003 based on a fixed-effects meta-analysis). This corresponds to an absolute mortality risk of 22% for IL-6 antagonists compared with an assumed mortality risk of 25% for usual care or placebo. The corresponding summary ORs were 0.83 (95% CI, 0.74-0.92; P <.001) for tocilizumab and 1.08 (95% CI, 0.86-1.36; P =.52) for sarilumab. The summary ORs for the association with mortality compared with usual care or placebo in those receiving corticosteroids were 0.77 (95% CI, 0.68-0.87) for tocilizumab and 0.92 (95% CI, 0.61-1.38) for sarilumab. The ORs for the association with progression to invasive mechanical ventilation or death, compared with usual care or placebo, were 0.77 (95% CI, 0.70-0.85) for all IL-6 antagonists, 0.74 (95% CI, 0.66-0.82) for tocilizumab, and 1.00 (95% CI, 0.74-1.34) for sarilumab. Secondary infections by 28 days occurred in 21.9% of patients treated with IL-6 antagonists vs 17.6% of patients treated with usual care or placebo (OR accounting for trial sample sizes, 0.99; 95% CI, 0.85-1.16). CONCLUSIONS AND RELEVANCE In this prospectivemeta-analysis of clinical trials of patients hospitalized for COVID-19, administration of IL-6 antagonists, compared with usual care or placebo, was associated with lower 28-day all-cause mortality