Speech of Hon. Salmon P. Chase.

Speech of Honorary Salmon P. Chase delivered at the Republican Mass Meeting in Cincinnati, August 21, 1855. Together with extracts from his speeches in the Senate of Kindred subjects. Consisting of 16 pages.https://stars.library.ucf.edu/civilwar-text/1023/thumbnail.jp

Letter, Salmon P. Chase to Elliot C. Cowden, September 2, 1862

This handwritten letter, dated September 8, 1862, is from Salmon P. Chase to Elliot C. Cowden as a response to Cowden\u27s letter to Chase on September 2. Chase informs Cowden that Mr. John Mack\u27s appointment was made by the President on the recommendation of some of the best the citizens of New York and is not under the purview of the Secretary of the Treasury. Chase goes on to encourage that perhaps experience will prove the selection not so injudicious as you think it now. A Treasury Department envelope postmarked Washington, D. C. Sep. 9, 1862 and addressed to Elliot C. Cowdin, Esq. in New York is included with the letter.https://scholarsjunction.msstate.edu/fvw-manuscripts-original-manuscripts/1130/thumbnail.jp

Letter, Salmon P. Chase to Thomas Bolton, October 14, 1848

This handwritten letter, dated October 14, 1848, is written from Salmon P. Chase to Thomas Bolton wherein Chase discusses the difficulties in getting a letter two Van Buren [Martin VanBuren?] and the difficulty of planning for VanBuren\u27s impending visit.https://scholarsjunction.msstate.edu/fvw-manuscripts-original-manuscripts/1123/thumbnail.jp

Letter to C. P. McIlvaine

Reply to letter from McIlvane dated August 13, 1861; God seems to be punishing us for our sins - complicity with slaveryhttps://digital.kenyon.edu/mcilvaine_letters/1066/thumbnail.jp

Note Clipping, Salmon P. Chase, Undated

This clipping from a note contains the signature of Salmon P. Chase, an American politician and jurist who served as the sixth chief justice of the United States.https://scholarsjunction.msstate.edu/fvw-manuscripts-original-manuscripts/1225/thumbnail.jp

Circular: To Collectors, Surveyors, and other Officers of the Customs, on the Northern & North-western waters of the United States.

This circular letter was issued by Salmon P. Chase just three weeks after Fort Sumpter was fired upon and the Southern coastal blockades were in effect. Abraham first instituted the blockade on 19 April 1861 by proclamation. The broadside is folded with a blank inside and is moderately browned.https://scholarsjunction.msstate.edu/fvw-artifacts/4498/thumbnail.jp

No straight lines – young women’s perceptions of their mental health and wellbeing during and after pregnancy: a systematic review and meta-ethnography

Background: Young mothers face mental health challenges during and after pregnancy including increased rates of depression compared to older mothers. While the prevention of teenage pregnancy in countries such as the United States and the United Kingdom has been a focus for policy and research in recent decades, the need to understand young women’s own experiences has been highlighted. The aim of this meta-ethnography was to examine young women’s perceptions of their mental health and wellbeing during and after pregnancy to provide new understandings of those experiences. Methods: A systematic review and meta-ethnographic synthesis of qualitative research was conducted. Seven databases were systematically searched and forward and backward searching conducted. Papers were included if they were from Organisation for Economic Co-operation and Development countries and explored mental health and wellbeing experiences of young mothers (age under 20 in pregnancy; under 25 at time of research) as a primary research question – or where evidence about mental health and wellbeing from participants was foregrounded. Nineteen papers were identified and the Critical Appraisal Skills Programme checklist for qualitative research used to appraise the evidence. Following the seven-step process of meta-ethnography, key constructs were examined within each study and then translated into one another. Results: Seven translated themes were identified forming a new line of argument wherein mental health and wellbeing was analysed as relating to individual bodily experiences; tied into past and present relationships; underpinned by economic insecurity and entangled with feelings of societal surveillance. There were ‘no straight lines’ in young women’s experiences, which were more complex than dominant narratives around overcoming adversity suggest. Conclusions: The synthesis concludes that health and social care professionals need to reflect on the operation of power and stigma in young women’s lives and its impact on wellbeing. It adds to understanding of young women’s mental health and wellbeing during and after pregnancy as located in physical and structural factors rather than individual capacities alone

Canine Morphology: Hunting for Genes and Tracking Mutations

In this essay, Abigail Shearin and Elaine Ostrander discuss the proposed genomic mechanisms for the extraordinary level of phenotypic variation observed in the domestic dog and the evidence detailing the variants responsible for the many shapes, sizes, textures, and colors of man's best friend

Analysis of large versus small dogs reveals three genes on the canine X chromosome associated with body weight, muscling and back fat thickness

International audienceDomestic dog breeds display significant diversity in both body mass and skeletal size, resulting from intensive selective pressure during the formation and maintenance of modern breeds. While previous studies focused on the identification of alleles that contribute to small skeletal size, little is known about the underlying genetics controlling large size. We first performed a genome-wide association study (GWAS) using the Illumina Canine HD 170,000 single nucleotide polymorphism (SNP) array which compared 165 large-breed dogs from 19 breeds (defined as having a Standard Breed Weight (SBW) >41 kg [90 lb]) to 690 dogs from 69 small breeds (SBW ≤41 kg). We identified two loci on the canine X chromosome that were strongly associated with large body size at 82–84 megabases (Mb) and 101–104 Mb. Analyses of whole genome sequencing (WGS) data from 163 dogs revealed two indels in the Insulin Receptor Substrate 4 (IRS4) gene at 82.2 Mb and two additional mutations, one SNP and one deletion of a single codon, in Immunoglobulin Superfamily member 1 gene (IGSF1) at 102.3 Mb. IRS4 and IGSF1 are members of the GH/IGF1 and thyroid pathways whose roles include determination of body size. We also found one highly associated SNP in the 5’UTR of Acyl-CoA Synthetase Long-chain family member 4 (ACSL4) at 82.9 Mb, a gene which controls the traits of muscling and back fat thickness. We show by analysis of sequencing data from 26 wolves and 959 dogs representing 102 domestic dog breeds that skeletal size and body mass in large dog breeds are strongly associated with variants within IRS4, ACSL4 and IGSF1

Multi-messenger observations of a binary neutron star merger

On 2017 August 17 a binary neutron star coalescence candidate (later designated GW170817) with merger time 12:41:04 UTC was observed through gravitational waves by the Advanced LIGO and Advanced Virgo detectors. The Fermi Gamma-ray Burst Monitor independently detected a gamma-ray burst (GRB 170817A) with a time delay of ~1.7 s with respect to the merger time. From the gravitational-wave signal, the source was initially localized to a sky region of 31 deg2 at a luminosity distance of 40+8-8 Mpc and with component masses consistent with neutron stars. The component masses were later measured to be in the range 0.86 to 2.26 Mo. An extensive observing campaign was launched across the electromagnetic spectrum leading to the discovery of a bright optical transient (SSS17a, now with the IAU identification of AT 2017gfo) in NGC 4993 (at ~40 Mpc) less than 11 hours after the merger by the One- Meter, Two Hemisphere (1M2H) team using the 1 m Swope Telescope. The optical transient was independently detected by multiple teams within an hour. Subsequent observations targeted the object and its environment. Early ultraviolet observations revealed a blue transient that faded within 48 hours. Optical and infrared observations showed a redward evolution over ~10 days. Following early non-detections, X-ray and radio emission were discovered at the transient’s position ~9 and ~16 days, respectively, after the merger. Both the X-ray and radio emission likely arise from a physical process that is distinct from the one that generates the UV/optical/near-infrared emission. No ultra-high-energy gamma-rays and no neutrino candidates consistent with the source were found in follow-up searches. These observations support the hypothesis that GW170817 was produced by the merger of two neutron stars in NGC4993 followed by a short gamma-ray burst (GRB 170817A) and a kilonova/macronova powered by the radioactive decay of r-process nuclei synthesized in the ejecta