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Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.

Author: Aawsaj Y.
Abad Gurumeta A.
Abad-Motos A.
Abate E.
Abatini C.
Abbadessa F.
Abbas A. M.
Abbassi-Ghadi N.
Abbott D.
Abbott T.
Abd Elazeem H. A. S.
Abdalla M.
Abdallah M.
Abdel Al S.
Abdel Jalil R.
Abdeldayem H.
Abdelkader Salama I.
Abdelkarem M. M.
Abdelkarim M.
Abdelmajeed A.
Abdelrahman A.
Abdelrahman S.
Abdelsamed A.
Abdou M.
Abdulkareem A.
Abdulwahed E.
Abdur-Rahman L.
Abel M. K.
Abellan M.
Aboelkassem Ibrahim A.
Abosamak N. E.
Abou Chaar M. K.
Abou-Khalil J.
Abouassi A.
Aboulkassem H.
Abreu Da Silva A.
Abu J.
Abu Za'nouneh F. J.
Abu-Nayla I.
Abubakar A.
Acebes Garcia F.
Achalandabaso Boira M.
Acher A.
Acrich E.
Adamina M.
Adamoli L.
Addae-Boateng E.
Aderombi A.
Adeyeye A.
Adiamah A.
Adishesh M.
Agapov M.
Aggarwal A.
Aghayeva A.
Agilinko J.
Agnes A.
Agostini C.
Agoston P.
Agrawal A.
Agresta F.
Aguado H.
Aguilar Gonzalez M.
Aguzzoli L.
Ahad S.
Ahmadi N.
Ahmeidat A.
Ahn J. H.
Aiken T.
Aime A.
Ajlan A.
Akalin M.
Akaydin E.
Akeel N.
Akgor U.
Akhtar M. A.
Akhter Rahman M. M.
Akilli H.
Akin E.
Akkour K.
Akmenkalne L.
Al Abdallah M.
Al Awwad S.
Al Habes H.
Al Maadany F. S.
Al Raddadi R.
Al-Habib A.
Al-Habsi R.
Al-Ishaq Z.
Al-Khayal K.
Al-Masri M.
Al-Mohammad A.
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Al-Najjar H.
Al-Omishy H.
Al-Sarireh B.
AL-Sayed M.
Al-Tamimi Y.
Alaa S.
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Albertsmeier M.
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Publication venue: J Clin Oncol
Publication date: 01/01/2020
Field of study

PURPOSE: As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19-free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS: This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19-free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS: Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19-free surgical pathways. Patients who underwent surgery within COVID-19-free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19-free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score-matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19-free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION: Within available resources, dedicated COVID-19-free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

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Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic

Author: 14 | COVIDSurg COllabOratIVe Tzovaras G. (General University Hospital of Larissa)
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Lima M. J.
Linari C.
Litta F.
Litvina Y.
Lizzi V.
Loch F. N.
Lomonosov Moscow State University). Saudi Arabia: Alshahrani M.
Long C.
Longhi M.
Lopes L.
Lopez F.
Lora- Cumplido P. Sosa M. V. (Hospital de Cabueñes)
Lorenzon L.
Losada M. (Hospital Universitario del Sureste)
Lott N.
Loubani M.
Loutzidou L. (George Papanikolaou General Hospital of Thessaloniki)
Lowery A.
Lozano Lominchar P.
Lucchini S. M. (Sanatorio Allende). Australia: Cecire J.
Luglio G.
Lunghi E. G.
Lynch N.
Lázaro A.
Löffler M. W.
Löfgren N.
M. elghazaly S.
MacCabe T.
MacDonald L.
Machado D.
Machado N.
Madonini M.
Maffioli A. (Ospedale Luigi Sacco Milano)
Magee C. Powell S. (Wirral University Teaching Hospital)
Magowan D.
Mahendran V. (Worcestershire Royal Hospital)
Mahmood M.
Mahmoud Ali F. (Newcastle Upon Tyne Hospitals NHS Foundation Trust. )
Maida P.
Majbar A. M.
Majkowska A.
Mak T. W. C.
Malapati H.
Malcolm F. L.
Malgras B. (Hia Begin)
Malibary N.
Mall J. (KRH Nordstadt-Siloah Hospitals)
Maltinti G.
Manatakis D. K.
Mancini S.
Manku B.
Manso M. I.
Manson J.
Mantoglu B. (Sakarya University Faculty of Medicine)
Manu N.
Maqueda González R.
Marano A.
Marcos-Santos P.
Margalit A.
Mari G.
Marialva J.
Mariani N. M.
Marie-Macron L. (Centre Hospitalier Avignon)
Marino Cosentino L.
Marino M. V.
Markaryan D.
Markovic I.
Markovic V.
Maroli A.
Marques R.
Marqueta De Salas M.
Marra A. A.
Marra E.
Marte G.
Martin E.
Martin-Perez E. (Hospital Universitario de la Princesa)
Martinez German A.
Martins D.
Martins dos Santos G.
Martins Jordão D.
Martins R.
Martín L.
Martín-Arévalo J.
Martínez Chicote C.
Martínez-Hurtado E.
Martínez-Pinedo C.
Martínez-Pérez P.
Marx W. (SUNY Upstate University Hospital)
Marzi F.
Marçal A.
Marín H.
Massey L.
Massie E.
Massobrio A.
Mastoridis S.
Math S.
Matić S.
Matos Costa P. (Hospital Garcia de Orta)
Matute M.
Maté P.
Maw A.
McAleer J.
McAree B.
McCanny A.
McCluney S.
McCormick P.
McDermott F.
McElhinney K.
McEwen R. (University College London Hospital)
McGivern K.
McIntyre J.
McKevitt K.
McLarty N.
McNicol F.
Mehigan B. J.
Mehraj A.
Meima-van Praag E. M.
Memon A. S.
Memos N.
Mendes F. (Centro Hospitalar Cova da Beira)
Mendes J. R.
Mendoza-Moreno F.
Meneghini S.
Menoufia University). Finland: Kauppila J. H.
Mercado M. Á.
Metwalli M.
Michalopoulos N.
Michalski C.
Michel M.
Migliore M.
Mignot G.
Miguel T.
Mihanovic J.
Mihmanli M.
Miladinov M.
Milan)
Milano)
Milanović M.
Mills S.
Milne K.
Mingoli A.
Minicozzi A.
Ministry of National Guard
Minto G.
Mir I.
Mirabella A.
Miranda P.
Mitchell D.
Mithany R.
Mitrofan C. G.
Miu V.
Mochet S. Usai A. (Ospedale Regionale Umberto Parini)
Mohamed Sidek A. S.
Mohammad Z.
Mohammed M. M.
Mohan H.
Mohd Yunus M. F.
Mohsine R.
Mondovì)
Mongelli F. (Ente Ospedaliero Cantonale)
Montelatici M.
Monteleone M. (San Leopoldo Mandic)
Montella M. T.
Montori G.
Mora-Guzmán I. (Hospital Santa Bárbara)
Morais H.
Moras L.
Morelli L.
Morgan R.
Moritani K. (National Cancer Center Hospital). Jordan: Al Abdallah M.
Moro-Valdezate D.
Morris A.
Morsi A.
Mosley F. (Bradford Royal Infirmary)
Moss J.
Moura F.
Mourad M.
Muguerza J. M.
Muiesan P.
Mukherjee S.
Mulligan C.
Muratore A.
Murphy C.
Mustafa A. (Gateshead Health NHS Foundation Trust)
Mutter D.
Muzamil J.
Muñoz Camarena J. M.
Muñoz-Atienza V.
Nafees Ahmed R.
Nageh M. A.
Nahm C. (Leeds Teaching Hospitals Trust)
Nally D.
Nassa H.
Nassif M.
Natale J.
Navaratne L.
Nazir S.
Neary P. C.
Neary P. M.
Neely D. (Antrim Area Hospital – Northern Health and Social Care Trust)
Nel D.
Nelli T.
Neri J.
Nespoli L. C. Tamini N. (Ospedale San Gerardo)
Nessim C.
Newman T.
Newton C. (University Hospitals Bristol NHS Foundation Trust)
Newton K.
Ng H. J. (Dumfries and Galloway Royal Infirmary)
Ng S. S. M. (Prince of Wales Hospital)
Ng V.
Ng V. (Medway Hospital)
Nikaj H. (Azienda Ospedaliero Universitaria Maggiore della Carità)
Nikolic S.
Nitschke C.
Nogueira O.
Nogueiro J.
Nogués A.
Nolan G. J.
Norcini C. (San Giovanni di Dio)
Nordberg M.
Nouh T.
Novello S.
Nowak K. Reinhard T. (Romed Klinikum Rosenheim)
Ntziovara A. M.
Nunes Coelho M.
Nunez-Garcia B.
Nuñez del Barrio H.
Obeidat K. (King Abdullah University Hospital)
Oguttu B. (Kampala International University Teaching Hospital). UK: Agilinko J.
Olasehinde O.
Oliva Mompean F.
Oliveira A.
Olivier J. (Weston General Hospital)
Olivieri M.
Olson K. A.
Onos L.
Oosterlinck W.
Oosterling S. (Spaarne Gasthuis)
Opocher E.
Ortega Vázquez I.
Ortiz de Solórzano Aurusa F. J.
Osman N. (Alexandria Medical Research Institute)
Osorio A.
Otero A.
Ovejero Merino E.
Owen H.
Owens P.
Oyende O.
Ozben V.
Ozgediz D.
Ozmen B. B. (Acibadem Atakent Hospital)
O’Brien H.
O’Brien S.
O’Malley S.
O’Riordan J. M.
O’Shea M.
Pacheco Sánchez D.
Padilla-Valverde D.
Padmore G.
Pagano G.
Palagi S.
Palmeri M.
Panahi P.
Papaconstantinou I.
Papatheodorou P.
Paquette N.
Parasyris S.
Parello A.
Parente A.
Parini S.
Parise P.
Parkin E. (Royal Preston Hospital)
Parkins K.
Parlanti D.
Parmar C.
Parra Baños P. A.
Parray F.
Parreira R. (Hospital do Divino Espírito Santo)
Parseliunas A.
Parwaiz I.
Pascale IRCCS)
Pascale IRCCS)
Paspaliari D.
Passot G. (Hopital Lyon Sud)
Patel K.
Patel M.
Patel P.
Patil S.
Patrone R. (HPB Surgical Oncology Unit – Istituto Nazionale Tumori Fondazione
Patrício B.
Pattyn P. (Az Delta)
Pavlov M.
Pedrazzani C.
Peirce C. (University Hospital Limerick)
Pejnovic L.
Pejovic I.
Pellegrino L.
Pellino G. (Vall d’Hebron University Hospital). Sri Lanka: Arulanantham A.
Peluso C.
Peralta Ferreira M.
Pereca J. (University Hospital Ayr)
Pereira A.
Pereira C.
Pereira R.
Pereira Rodrigues A.
Perez D.
Perez Gonzalez M.
Pergolini I. Reim D. (Klinikum Rechts der Isar TUM School of Medicine)
Perivoliotis K.
Peros G. (Kantonsspital Winterthur). Turkey: Aghayeva A.
Perotto L. O.
Perra T.
Persiani R.
Pertile D.
Petrillo A.
Petropoulos K.
Peyroteo M.
Pezzuto A. P.
Peña Ros E.
Phan D. Townend D. (Lismore Base Hospital)
Phillips E.
Picardo A. L.
Pickett L. (Connolly Hospital Blanchardstown)
Picón Rodríguez R.
Pieniowski E. (Stockholm South General Hospital)
Piessen G.
Pieve Emanuele (Mi))
Pina S.
Pinto J. Tojal A. (Centro Hospitalar Tondela-Viseu)
Pipitone Federico N. S. (Edoardo Agnelli)
Pisani Ceretti A. (ASST Santi Paolo E. Carlo)
Pisanu A.
Pizarro M. J.
Pizzini P. (Ospedale Maggiore di Lodi)
Pla Marti V. (Hospital Clínico Universitario de Valencia)
Poch C.
Pockney P. (John Hunter Hospital)
Podda M. (Cagliari University Hospital)
Poggioli G.
Polydorou A.
Popoola A. (University of Ilorin Teaching Hospital). Pakistan: Jamal A.
Porcu A.
Portinari M.
Posadas-Trujillo O. E.
Posma-Bouman L. (Slingeland Ziekenhuis)
Potter R. (Royal Bournemouth Hospital)
Pourcher G.
Pozotou I.
Praetorius C.
Prando D.
Presl J.
Price C.
Prieto Calvo M.
Prieto Nieto M. I.
Pronk A. J. M.
Prosperi P.
Provozina A. (Immanuel Kant Baltic Federal University
Pruvot F. R.
Pérez Sánchez M. A.
Pérez-Saborido B.
Qasem A. (Al- Basheer Hospital)
Qatora M. S.
Quante M.
Qureshi A.
Raby-Smith W.
Rai . L (Dr Ruth K. M. Pfau Civil Hospital)
Rajaretnam N. (Royal Devon and Exeter Hospital)
Rakvin I. (Zadar General Hospital). Cyprus: Frantzeskou K.
Ramachandran A. (Tunbridge Wells Hospital)
Ramamoorthy 18 | COVIDSurg COllabOratIVe R.
Ramcharan S.
Ramesh P.
Ramirez Faraco M.
Ramos Bonilla A.
Ramos-Martín P.
Ramwell A.
Rapaport S.
Rashid A. (SMHS Hospital
Rashid M. M.
Rattizzato S.
Ratto C.
Ravindrakumar S.
Ravindran S.
Rayamajhi S. (Groote Schuur Hospital). Spain: Paniagua García Señorans M.
Raymond T.
Razafindrahita J. B.
Redfern J.
Rega D.
Regional Clinical Hospital)
Reilly J.
Revez T.
Rey Valcarcel C.
Reynolds I. S.
Ribeiro A.
Ribeiro C. G.
Ribeiro R.
Ribeiro V. I.
Ribolla M. (Ospedale Guglielmo da Saliceto Piacenza)
Rice D.
Richards T.
Ridgway P. F.
Righini E. (Azienda Unità Sanitaria Locale di Ferrara
Riley C.
Rimonda R.
Ringressi M. N.
Ripollés-Melchor J.
Risaliti M.
Rizzi A. (ASST Sette Laghi-Varese)
Robinson A.
Rodimov S.
Rodrigo V. S. D. (District General Hospital Chilaw)
Rodriguez J. L.
Rodríguez Gómez L. (Severo Ochoa University Hospital)
Rogers L. (Derriford Hospital)
Rojo López J. A.
Romano M.
Romero de Diego A.
Ronellenfitsch U. (University Hospital Halle (Saale))
Rooney S.
Rosa F.
Rose J.
Roslani A. C. (University Malaya Medical Centre). Mexico: Buerba G. A.
Rossi S.
Rottoli M.
Roy Mahapatra S.
Royle T.
Rozzano (Mi) and Humanitas University
Rubio-Perez I.
Ruivo A.
Ruiz Escobar A. (Infanta Leonor University Hospital)
Ruiz Soriano M.
Ruiz-Marín M.
Russ J.
Rutegård M. (Umea University Hospital). Switzerland: Arigoni M.
Rutherford D.
Ruzzenente A.
Ryan M. (University Hospital Waterford/University College Cork). Italy: Macina S. (ASST Mantua)
Ryan É. (University Hospital Galway)
Ryska O. (Royal Lancaster Infirmary)
Río Lafuente F. D.
Saad M. M.
Saafan T.
Saavedra J.
Sabah)
Sabratha)
Sabry A.
Saeed S.
Saez Carlin P.
Sagar J.
Sagnotta A. (Ospedale San Filippo Neri)
Sahin I. (Acibadem Altunizade Hospital)
Sahnan K. (Northwick Park Hospital)
Salazar A.
Saleem A.
Salem H.
Salgado-Nesme N.
Salimoğlu S.
Salindera S.
Sallam I.
Samih A.
Samir Abdelaal A.
Samison L. H. (Joseph Ravoahangy Andrianavalona Hospital). Malaysia: Hamdan K. H.
Samkari A.
Sammarco G.
Sammour T. (Royal Adelaide Hospital)
Sampaio da Nóvoa Gomes Miguel I. I. (Centro Hospitalar Universitário do Algarve – Unidade de Portimão)
Sampietro G. M. (Ospedale di Rho – ASST Rhodense)
San Francisco (UCSF))
Sanchez Cabezudo Noguera F.
Sanchez Gonzalez J.
Sanchez Jimenez R.
Sanchez-Pelaez D. (Hospital General Universitario de Ciudad Real)
Sancho-Muriel J. (Hospital Universitario Y Politécnico la Fe)
Sanchon L.
Sanli A. N.
Santanach C.
Santarrufina Martinez S.
Santero-Ramirez M. S.
Santos P. M. D. D.
Santos R.
Santos-Sousa H.
Sanz Larrainzar A.
Sanz Ortega G.
Sanz-Lopez R.
Sapienza P.
Sapre D.
Saraiva P.
Sarantitis I.
Sarigul M.
Sarin A.
Sarjanoja E. (Länsi-Pohja Central Hospital)
Sarma D. R.
Sarre C. (Instituto Nacional de Ciencias Médicas y Nutrición ‘Salvador Zubirán’). Morocco: Amrani L.
Sartarelli L.
Sarveswaran J.
Sasapu K. (Diana Princess of Wales Hospital Grimsby)
Sasia D.
Saudí S. (Hospital Universitario Miguel Servet)
Sauvain M. (Pourtales Neuchatel Hospital)
Sauvat F. (CHU Réunion). Romania: Bezede C.
Savković N.
Sayyed R. (Patel Hospital)
Scabini S.
Scalabre A. (Chu Saint Etienne)
Scanu A. M. (Cliniche San Pietro
Schiavo M. (Ospedale Vittorio Emanuele III – Carate Brianza)
Schiergens T.
Schineis C. (Charité University Medicine
Schizas D.
Schlesinger N.
Schwartz P.
Scott L. (Pinderfields Hospital)
Scotton G. (St Moritz Hospital)
Scrima O.
Sechenov Medical State University)
Seebah K.
Seeliger B. (Strasbourg University Hospitals/IHU-Strasbourg)
Seguin-Givelet A.
Sehgal T.
Selmani J.
Semina E. (Moscow Research and Educational Center
Senossi O.
Serevina O. L.
Serralta de Colsa D. (Infanta Sofía University Hospital)
Serrano González J. (Hospital Universitario de Torrejón de Ardoz)
Serrano-Navidad M.
Sert İ.
Seymour Z. (Ysbyty Gwynedd). USA: Haynes A.
Sganga G. (Fondazione Policlinico Universitario Agostino Gemelli IRCCS)
Sgrò A.
Shah J. (North Manchester General Hospital)
Shah S. (The Whittington Hospital)
Shah Z. A.
Shaikh I.
Shaikh S.
Sharabiany S. (Amsterdam UMC
Sharma P. (Aberdeen Royal Infirmary)
Shehata S.
Shenfine A. (Northumbria NHS Hospital Trust)
Shenit K. (Alexandria Main University Hospital)
Sheridan K.
Sherief M.
Sherif A. (Misr Cancer Center)
Sherif A. E. (National Liver Institute
Sherif G. (National Cancer Institute)
Shokuhi P.
Shortland T.
Sian T.
Sibilla M. G.
Sidiropoulos T.
Silva M.
Silva N.
Silva R.
Silveira Nunes I.
Simões J. (Centro Hospitalar e Universitário de Coimbra)
Singh A.
Singh S. (Queen’s Hospital Romford)
Skrovina M.
Smith C.
Smith H. (Bispebjerg Hospital). Egypt: Al Sayed M.
Smith L.
Smith. J (St James’s Hospital)
Soares A. P.
Soh J. Y.
Sohrabi C.
Solari F.
Soriero D. (IRCCS Ospedale Policlinico San Martino)
Sorrentino L. (Fondazione IRCCS Istituto Nazionale dei Tumori
Sorribas Grifell M.
Soto Montesinos C. (Fundació Althaia – Xarxa Assistencial Universitària de Manresa)
Souadka A. (Institut National d’Oncologie
Soulikia K.
Sousa Fernandes M. (Hospital Beatriz Angelo)
Sousa R. (Centro Hospitalar Universitário Lisboa Central)
Sousa S.
Spagni G.
Spampinato M. G. (Vito Fazzi
Spartalis E.
Spencer N.
Spiezio G. (Colorectal Surgical Oncology Unit – Istituto Nazionale Tumori Fondazione
Spinelli A. (Humanitas Clinical and Research Center IRCCS
Sreedharan L.
Sriram R. K.
Srishankar S. (Teaching Hospital Anuradhapura). Sudan Ali Adil A. K. (Al-Rajhi). COVIDSurg COllabOratIVe | 17 Sweden: Älgå A.
St John S.
Stafford J. (George Eliot Hospital)
Stavrinidou O.
Steele C. (Sheffield Teaching Hospital NHS Foundation Trust)
Steidle C.
Steinke J.
Stevens K.
Stevenson J. (The Ottawa Hospital). Croatia: Bačić G.
Stevic D.
Stewart K. E.
Stylianides N. (Manchester Royal Infirmary)
Stylianidis G. (Evaggelismos General Hospital)
Subhi M. T. (Alkhadra Hospital)
Subocius A.
Subramaniam S. (Queen Elizabeth Hospital and Universiti Malaysia Sabah
Sundaram Venkatesan G. (Glan Clwyd Hospital)
Suszták N. (Szent Borbála Kórház). India: Bhat G. A.
Sutherland A. (Coffs Harbour Health Campus)
Swinson B. (Royal Brisbane and Women’s Hospital). Austria: Messner F.
Syed W. A. S.
Syllaios A.
Szatmary P.
Szubota I. (Hospital and Oncological Centre Novy Jicin). Denmark: Ebbehøj A. L.
Sánchez del Pueblo C.
Sánchez Fuentes N.
Sánchez- Pernaute A.
Sánchez- Rubio M.
Sánchez-García S.
Taddei A.
Tadic B.
Taibi A. (Chu Limoges)
Talal El-Abur I.
Talwar R. (Luton and Dunstable University Hospital)
Tammaro P.
Tan J. A.
Tan X. S.
Tanal M.
Tang A. M.
Tanzanu M.
Tartaglia D. (Azienda Ospedaliero Universitaria Pisana)
Tasis N. (Athens Naval and Veterans Hospital)
Tatar O. C.
Tavares F.
Tayeh S. (Homerton University Hospital)
Tebala G. D.
Teixeira J. (Centro Hospitalar Universitário do Algarve – Unidade de Faro)
Teixeira M. (Centro Hospitalar do Tamega e Sousa)
Tejero- Pintor F. J. (Hospital Universitario Río Hortega)
Testa V. (Santa Croce E. Carle Hospital
Tewari N. (University Hospitals Coventry and Warwickshire NHS Trusts)
Tezas S. (Furness General Hospital)
Thaha M.
Thanapal M. R. (Hospital Kuala Lumpur)
Theodosopoulos T.
Theophilidou E. (Royal Derby Hospital)
Thian A.
Thomas A. (Royal Liverpool University Hospital)
Thompson D. (Morriston Hospital Swansea)
Thornhill M. (Dell Seton Medical Center at the University of Texas)
Thrumurthy S. (Epsom and St Helier University Hospitals NHS Trust)
Thulasiraman S. V.
Timbrell S.
Tirloni L.
Titu S. (Prof. Dr. Ion Chiricuta Institute of Oncology). Russia: Garmanova T.
Tonini V. (S. Orsola-Malpighi Hospital)
Torres A. (Hospital Clínico de Madrid)
Torres Arcos C.
Townson A.
Trabulsi N. (King Abdulaziz University Hospital)
Travaglio E. (Regina Montis Regalis Hospital
Tribillon E. (Institut Mutualiste Montsouris)
Troncoso Pereira P. (Hospital Mateu Orfila)
Tropeano F. P. (Federico II University Hospital)
Trujillo Díaz J.
Tsai L.
Tsarkov P.
Tsiamalou I.
Tsiaoussis I.
TU Dresden)
Tucci R. (Azienda Ospedaliera Universitaria Careggi)
Tufo A. (Ospedale del Mare)
Tugmen C.
Tulina I. (Clinic of Coloproctology and Minimally Invasive Surgery
Tuncer K.
Turnbull A. (Victoria Hospital Kirkcaldy)
Turrado-Rodriguez V.
Turri G. (Azienda Ospedaliera Universitaria Integrata di Verona)
Tweedle E. (Addenbrooke’s Hospital)
Ugarte-Sierra B. (Hospital Universitario de Galdakao)
Uludağ S. S.
Umair M.
Universiti Sains Malaysia)
University of Amsterdam)
Università di Ferrara)
Université Mohammed V Rabat). Netherlands: Hompes R.
Uras C. (Acibadem Maslak Hospital)
Urbani A. (Azienda Ospedaliero Universitaria San’anna)
Urbieta A. (Hospital Universitario la Paz)
Uslu G.
Utkan N. Z.
Uyanik M. S. (Samsun Training and Research Hospital)
Uzunoglu F. G. (University Medical Center Hamburg–Eppendorf). Greece: Antonakis P.
Vaccarella G. (Azienda Ospedaliera Ospedali Riuniti Villa Sofia-Cervello)
Valbuena Jabares V. (Marqués de Valdecilla University Hospital)
Valdes- Hernandez J. (Hospital Universitario Virgen Macarena)
Valero Soriano M. (Hospital General Reina Sofía)
Valle Rubio A. (Getafe University Hospital)
Valverde S. (Hospital Clinic Barcelona)
Van den Eynde J.
Van den Eynde R. (Uz Leuven). Bulgaria: Sokolov M. (University Hospital Alexandrovska). Canada: Boutros M.
Varma M. (University of California
Vasljević J.
Vassiliu P. (Attikon University General Hospital)
Vaz Pereira R.
Vaz S. (Centro Hospitalar e Universitário de São João)
Velchuru V.
Velickovic D. (Clinic for Digestive Surgery
Velidedeoglu M.
Venn M. (Royal London Hospital)
Venskutonis D. (Lithuanian University of Health Sciences Kaunas Clinical Hospital). Madagascar: Rasoaherinomenjanahary F.
Vera Mansilla C. (Hospital Universitario Principe de Asturias)
Verberne C. (John Radcliffe Hospital)
Vergari R. (Ospedali Riuniti di Ancona)
Vernon L. (Cork University Hospital)
Vervoort D.
Vescio G. (University ‘Magna Graecia’ of Catanzaro)
Vezakis A. (Aretaieion Hospital)
Videira J. F. (IPO Porto). Réunion: Kassir R.
Vieira B. (Centro Hospitalar de Trás-Os-Montes e Alto Douro
Vieira Caroço T. (IPO Coimbra)
Vieira Paiva Lopes A. C. (Hospital de Torres Vedras – Centro Hospitalar do Oeste)
Vignali A. (San Raffaele Scientific Institute
Vigorita V. (Álvaro Cunqueiro Hospital)
Vijayan D. (Queen Elizabeth Hospital Birmingham)
Villalabeitia Ateca I. (Hospital Universitario Cruces)
Vimalachandran D. (Countess of Chester Hospital)
Viswanath Y. K. S. (James Cook University Hospital)
Vitali A. (Ospedale San Giovanni di Dio)
Vitone L. (Royal Blackburn Hospital)
Vives R. V. (Bellvitge University Hospital)
Vo U. G. (Fiona Stanley Hospital)
Von Papen M.
Vovola F. (Ospedali Riuniti Azienda Ospedaliera Universitaria Foggia)
Vucic N.
Vázquez Fernández A. (Hospital Clínico Universitario de Valladolid)
Wadham B. (The University Hospital of South Manchester)
Walkes K. (Queen Elizabeth Hospital). Belgium: Flamey N.
Wani R. (Sher-I-Kashmir Institute of Medical Sciences)
Waqar S. H. (Pakistan Institute of Medical Sciences). Poland: Major P. (Jagiellonian University Medical College). Portugal: Azevedo C.
Warren O. (Chelsea and Westminster Hospital)
Watson L. J. (Sunderland Royal Hospital)
Watson N. (King’s Mill Hospital)
Weitz J.
Welsch T. (Carl-Gustav-Carus University Hospital
Werner J. (LMU Klinikum Campus Innenstadt)
Westwood E. (James Paget University NHS Foundation Trust Hospital)
Whelan M. (Tallaght University Hospital)
Whitmore H. (Torbay and South Devon NHS Trust)
Wilkin R. J. W. (South Warwickshire NHS Foundation Trust)
Wilkins A. (Hull University Teaching Hospitals NHS Trust)
Williams G. (Royal Gwent Hospital)
Williams K. (St George’s Hospital)
Wilson M. (Forth Valley Royal Hospital)
Wimmer A. (Paracelsus Medical University Salzburg). Barbados: Barker D.
Wong M.
Worku D. (Queens Medical Centre)
Wullschleger M. (Gold Coast University Hospital)
Xavier R. G.
Xenaki S.
Xynos E. (University Hospital of Heraklion Crete and Interclinic Hospital of Crete). Hong Kong: Futaba K.
Yang W.
Yassin N. (Royal Wolverhampton NHS Trust)
Ye G.
Yesantharao P.
Yetkin S. G. (Sisli Hamidiye Etfal Training and Research Hospital)
Yeşilyurt D. (University of Health Sciences Tepecik Training and Research Hospital)
Yiallourou A. (Nicosia General Hospital). Czechia: Martinek L.
Yıldırım A.
Yildiz A. (Yildirim Beyazit University Yenimahalle Training and Research Hospital). Uganda: Lule H.
Young R. (York Teaching Hospitals NHS Trust)
Yousof E. A. (Assiut University Hospital)
Youssef M. (Norfolk and Norwich University Hospital)
Yurttas C. (University Hospital Tuebingen)
Yánez C. (Royo Villanova)
Yüksel E. (Kocaeli University Teaching Hospital)
Zafar S. N. (University of Wisconsin)
Zakaria A. D.
Zakaria Z. (School of Medical Sciences and Hospital
Zambon M. (Policlinico Umberto I Sapienza University of Rome)
Zanus G. (Ca’ Foncello Treviso – DISCOG – Università di Padova)
Zegarac M. (Institute for Oncology and Radiology of Serbia)
Zelić M. (University Hospital Center Rijeka)
Zengin A. K. (Istanbul Universty – Cerrahpaşa Medical Faculty)
Zerbib P. (CHU Lille)
Zervas K.
Zese M. (Santa Maria degli Angeli Hospital ULSS 5 – Adria)
Zhang H. (Concord Repatriation General Hospital)
Zizzo M. (Azienda Unità Sanitaria Locale – IRCCS di Reggio Emilia)
Zografos C. (Laiko University Hospital)
Zorrilla Ortúzar J. (Hospital General Universitario Gregorio Marañón)
Zourntou S. (General Hospital of Larissa ‘Koutlimpaneio and Triantafylleio’)
Zubaidi A. M. (King Saud University). Serbia: Aleksić L.
Ângelo M.
Çelebi F.
Çolak E.
Öfner D. (Medical University of Innsbruck)
Öhlberger L.
Özçelık M. F.
Öğücü H.
Überrück L.
Ćoza I.
Publication venue: 'Wiley'
Publication date: 01/01/2020
Field of study

This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic

Archivio della ricerca- Università di Roma La Sapienza

Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study

Author: Aawsaj Y.
Abad Gurumeta A.
Abad-Motos A.
Abate E.
Abatini C.
Abbadessa F.
Abbas A. M.
Abbassi-Ghadi N.
Abbott D.
Abbott T.
Abd Elazeem H. A. S.
Abdalla M.
Abdallah M.
Abdel Al S.
Abdel Jalil R.
Abdeldayem H.
Abdelkader Salama I.
Abdelkarem M. M.
Abdelkarim M.
Abdelmajeed A.
Abdelrahman A.
Abdelrahman S.
Abdelsamed A.
Abdou M.
Abdulkareem A.
Abdulwahed E.
Abdur-Rahman L.
Abel M. K.
Abellan M.
Aboelkassem Ibrahim A.
Abosamak N. E.
Abou Chaar M. K.
Abou-Khalil J.
Abouassi A.
Aboulkassem H.
Abreu Da Silva A.
Abu J.
Abu Za'nouneh F. J.
Abu-Nayla I.
Abubakar A.
Acebes Garcia F.
Achalandabaso Boira M.
Acher A.
Acrich E.
Adamina M.
Adamoli L.
Addae-Boateng E.
Aderombi A.
Adeyeye A.
Adiamah A.
Adishesh M.
Agapov M.
Aggarwal A.
Aghayeva A.
Agilinko J.
Agnes A.
Agostini C.
Agoston P.
Agrawal A.
Agresta F.
Aguado H.
Aguilar Gonzalez M.
Aguzzoli L.
Ahad S.
Ahmadi N.
Ahmeidat A.
Ahn J. H.
Aiken T.
Aime A.
Ajlan A.
Akalin M.
Akaydin E.
Akeel N.
Akgor U.
Akhtar M. A.
Akhter Rahman M. M.
Akilli H.
Akin E.
Akkour K.
Akmenkalne L.
Al Abdallah M.
Al Awwad S.
Al Habes H.
Al Maadany F. S.
Al Raddadi R.
Al-Habib A.
Al-Habsi R.
Al-Ishaq Z.
Al-Khayal K.
Al-Masri M.
Al-Mohammad A.
Al-Mukhtar A.
Al-Najjar H.
Al-Omishy H.
Al-Sarireh B.
AL-Sayed M.
Al-Tamimi Y.
Alaa S.
AlAamer O.
Aladeojebi A.
Alam F.
Alam N.
Alam R.
Alamri A.
Alanbuki A.
Alatar A.
Alawneh F.
Alazawi D.
Albertsmeier M.
Albi Martin B.
Alburakan A.
Alcaide Matas F.
Alconchel F.
Aldayri Z.
Aldecoa Ansorregui I.
Aldokali N.
Aleksic L.
Alemanno G.
Alexoudi V.
Alfaro-Goldaracena A.
Alfieri S.
Alga A.
Alghamdi M.
Alhalal H.
Alhamed A.
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Wallwork K.
Walton G.
Walton T.
Waqar S. H.
Warburton H.
Ward D.
Ward S.
Waris Farooka M.
Warren O.
Waseem S.
Wasim T.
Watson D.
Watson L. J.
Watson N.
Weaver H.
Webber L.
Weitz J.
Welsch T.
Wensley F.
Werner J.
West C.
West D.
Westwood E.
Whelan M.
Whelan P.
Whisker L.
Whitehall E.
Whitmore H.
Wilkin R.
Wilkins A.
Williams G.
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Williams K.
Williams M. A.
Williams T.
Williamson K.
Wilson M.
Wimberger P.
Wimmer A.
Winnand P.
Winter D.
Winter S.
Wolfer S.
Wong M. P. K.
Wong S.
Wong W. J.
Woodham A.
Woodun H.
Worku D.
Wright G.
Wullschleger M.
Wustrack R.
Xenaki S.
Xu M. J.
Xyda S. E.
Xynos E.
Yahaya A. S.
Yanez C.
Yang W.
Yassin N.
Ye G.
Yesantharao P.
Yesilyurt D.
Yetkin G.
Yiallourou A.
Yildirim A.
Yildiz A.
Ying Y.
Yip V.
Yordanov S.
Young R.
Yousof E. A.
Youssef A.
Youssef M.
Yuksel E.
Yurttas C.
Zacharoulis D.
Zafar S. N.
Zakai D.
Zakaria A. D.
Zakaria R.
Zakaria Z.
Zambelli M. F.
Zambon M.
Zamora L.
Zamvar V.
Zani S.
Zanotti S.
Zanus G.
Zapardiel I.
Zarabini A. G.
Zatecky J.
Zegarac M.
Zelic M.
Zeller N.
Zengin A. K.
Zerbib P.
Zervas K.
Zese M.
Zhang H.
Zivanovic M.
Zivkovic M.
Zizzo M.
Zografos C.
Zonta S.
Zorrilla Ortuzar J.
Zourntou S.
Zouzoulas D.
Zubaidi A.
Zullo A.
Publication venue: 'American Society of Clinical Oncology (ASCO)'
Publication date: 01/01/2021
Field of study

PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19–free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19–free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19–free surgical pathways. Patients who underwent surgery within COVID-19–free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19–free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score–matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19–free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION Within available resources, dedicated COVID-19–free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

Archivio istituzionale della Ricerca - Università degli Studi di Parma

The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study

Author: Abadia M
Abassy J
Abate E
Abbott Tom EF
Abdelaal Samir A
Abdeldayem H
Abdelkabir M
Abdelsamed A
Abdulwahed E
Abiyere H
Abou Chaar MK
Abukhalaf SA
Abukhalaf Sadi
Adamina Michel
Ademuyiwa Adesoji
Ademuyiwa Adesoji O
Adeyeye A
Adisa Adewale
Afzal MF
Agarwal Arnav
Aggarwal M
Agnes A
Agostini C
Agrawal A
Agrawal N
Agresta F
Aguiar Junior S
Ahmed A
Ahmed K
Ahmed Nafees R
Ahmed Z
Ahn JH
Aime A
Akhtar N
Akkulak Murat
Akrivou D
Al Abdallah M
Al Riyami S
Al Sayed M
Al-Masri M
Al-Najjar H
Al-Slaibi I
Alaa S
Alakaloko Felix
Alameer Ehab
Alamri Alex
Alawneh F
Albertsmeier M
Albertsmeier Markus
Alderson Derek
Aldokali N
Alemanno G
Alfieri S
Algallai M
Ali AA
Alkadiki Ghadah Z
Almaadany Faraj S
Almeida AC
Almeida-Reis R
Almezghwi H
Almond Max
Alrahawy M
Alser Osaid
Alshaar Muhammad
Alshareea E
Alshareef K
Alshryda Sattar
Alsoufi A
Altamirano Riquoir C
Altomare DF
Altomi I
Alurralde C
Alvarez MR
Alvi A
Alwarfly S
AlZAEDE S
Alzeerelhouseini IAH
Amaral MJ
Amira G
Amorim E
Amrani L
Anania G
Anastasi A
Andrade Kam da Silva A
Andrade R
Annessi V
Annicchiarico A
Antonakis P
Antonopoulou M
Aprile A
Aremu M
Arias-Amezquita F
Aribi N
Aribi S
Arkadopoulos N
Armao T
Armatura G
Arminio A
Arnaud Alexis P
Arora A
Arslan K
Ashoush F
Athanasakis E
Attia D
Augestad Knut Magne
Aversano A
Avlund T
Awada Barakat J
Ayasra F
Ayasra Faris
Ayasra Y
Ayub B
Ayubi A
Ayyaz M
Azevedo C
Azevedo J
Azevedo Jose
Azevedo P
Azman Mohd ZA
Azzam AY
Babalola O
Badra R
Bagraith K
Baili E
Balabel M
Balconi A
Baldari L
Baldi C
Baldini E
Bali K
Ballabio M
Ballouhey Q
Baloyiannis I
Bandovas JP
Bankhead-Kendall Brittany K
Banky B
Banuelos Romero E
Baptista VH
Barker D
Barlow Emma
Barod Ravi
Barone R
Baronio G
Barrat B
Barros Vieira A
Bartalucci B
Bartolini I
Bashir Y
Bass G
Batistotti P
Batstone Martin
Baxevanidou K
Beard David
Becker R
Bekele K
Belia F
Belkhadir ZH
Bellacci A
Belli A
Bellolio F
Bellora P
Belluco C
Belvedere A
Bendjemar L
Benkabbou A
Benson Ruth A
Bergamini C
Bergeat D
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Beyer K
Beyrne C
Bezerra Santos T
Bhangu Aneel A
Bhat GA
Bhat MA
Biala M
Bianchini M
Bianco F
Biel Juan Rey
Bigam D
Biondi A
Birolo SL
Bisagni P
Blanco-Colino Ruth
Bodanese B
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Bong C
Boni L
Bonilla A
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Bordoni P
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Bouchagier K
Bouche PA
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Brachini G
Bradulskis S
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Brar Amanpreet
Bravo Ana Minaya
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Bretherton Chris
Bristow Rob
Bromage Steve
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Brunelli Alessandro
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Buarque Igor Lima
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Bywater Edward
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Chisthi M
Chiva Luis
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Christensen P
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Chrysos E
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Cianflocca D
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da Silva Abreu A
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Faustino A
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Federico P
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Feo C
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Ferrari M
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Ferraz I
Ferreira C
Ferreira Peralta M
Ferro Carvalho C
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Fiore M
Fiore Marco
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Roslani April C
Rosseau Gail
Rossi S
Roszkowski R
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Roux A
Ruivo A
Ruiz Castro C
Russo IS
Rutegard Martin
Ruzzenente A
Ryan EJ
Ryan M
Saad MM
Sabry A
Sagnotta A
Sahid Nik Amin
Saklani A
Sakr A
Saksena AR
Salama Abdelkader
Saleem A
Salem H
Salem M
Salgado-Nesme N
Salindera S
Sallam I
Samadov E
Samih A
Samison LH
Sammarco G
Sammour T
Sampietro GM
Sani Ali S
Santos Costa D
Santos Irene
Santos PMDD
Santos R
Santos-Sousa H
Sapienza P
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Sarjanoja E
Sarre C
Sartarelli L
Sasia D
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Sayyed R
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Scabini S
Scalabre A
Scanu AM
Schache Andrew
Schache Andrew G
Schaller Karl
Schiavo M
Schiergens T
Schineis C
Schizas D
Schlesinger N
Schnitzbauer Andreas A
Scotton G
Scrima O
Seeliger B
Seenivasagam Kottayasamy R
Seenivasagam Rajkumar Kottayasamy
Seguin-givelet A
Segura-Sampedro Juan Jose
Sehouli Jalid
Seleim A
Selmani J
Sena G
Senossi O
Servadei Franco
Seshadri Ayloor R
Seyi-Olajide Justina O
Sganga G
Shah ZA
Sharabiany S
Sharma Neil
Shaw Catherine A
Shaw Richard
Shehata S
Shenit K
Sherief M
Sherif A
Sherif Ahmed Elshawadfy
Sherif G
Shokuhi P
Sholadoye TT
Shu Sebastian
Shylasree TS
Siaw-Acheampong Kwabena
Sibilla MG
Siddiqui MT
Sidek Mohamed AS
Sidiropoulos T
Silva A
Silva M
Silva N
Silva R
Silvestre D
Simoes JFF
Simoes Joana FF
Singh Jagdeep K
Singh MP
Singh R
Singh S
Skrovina M
Smart Neil
Smart Neil J
Smith H
Smith J
Soares Sampaio A
Soh JY
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Soliman H
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Soreide Kjetil
Soriero D
Sorrentino L
Souadka A
Sousa R
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Spagni G
Spampinato MG
Spartalis E
Spiezio G
Spinelli A
Spinelli Antonino
Spolini A
St John S
Stavrinidou O
Steidle C
Stevenson J
Stewart Grant D
Strate T
Stylianidis G
Subhi MT
Subocius A
Subramaniam S
Sund Malin
Sundar Sudha
Susztak N
Sutherland A
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Syed WAS
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Tabiri Stephen
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Testa V
Thanapal MR
Thekinkattil Dinesh
Theodosopoulos T
Thian A
Tirloni L
Tirotta Fabio
Tojal A
Tolani MA
Tom K
Tonini V
Tooulias A
Townen Philip
Townend D
Townend Philip
Travaglio E
Tribillon E
Tropeano FP
Tsiaoussis I
Tsoulfas G
Tsoulfas Georgios
Tucci R
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Umair M
Umar A
Urbani A
Usai A
Uzunoglu FG
Vaccarella G
Vale R
Valenzuela J
Vallance Abigail
Van de Putte D
Van den Eynde J
Van den Eynde R
van der Plas Willemijn
Van Heinsbergen M
Van Nieuwenhove Y
Van Ramshorst G
van Ramshorst Gabrielle H
Varghese Chris
Vasey C
Vassiliu P
Vaz S
Vaz-Pereira R
Veetil Kannummal S
Vendrame C
Venskutonis D
Vergari R
Vernon L
Vescio G
Vezakis A
Vidya Raghavan
Vieira A
Vieira B
Vignali A
Vignotto C
Vilar-Compte D
Vimalachandran Dale
Vimalchandra Dale
Violante T
Vishnoi JR
Vitali A
Vo UG
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Waqar SH
Warren Oliver J
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Wedderburn Duane
Weitz J
Welsch T
Werner J
Whelan M
Wilkins Alex
Willaert W
Wimmer A
Winter D
Winter Stuart C
Wong MP
Wood M
Wrigh Naomi
Wullschleger M
Xavier R
Xenaki S
Xynos E
Yadev I
Yang W
Ye G
Yezzaji H
Yiallourou A
Yousof EA
Yunus Mohd MF
Yurttas C
Zakaria AD
Zakaria Z
Zambon M
Zanus G
Zatecky J
Zelic M
Zerbib P
Zervas K
Zese M
Zhang H
Zizzo M
Zmora O
Zografos C
Zonta S
Zourntou S
Publication venue: 'Royal College of Obstetricians & Gynaecologists (RCOG)'
Publication date: 01/06/2022
Field of study

AIM: The SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery. METHODS: This was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4 weeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin. RESULTS: Overall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4 weeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, P = 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, P < 0.001). After adjustment, delay was not associated with a lower rate of complete resection (OR 1.18, 95% CI 0.90-1.55, P = 0.224), which was consistent in elective patients only (OR 0.94, 95% CI 0.69-1.27, P = 0.672). Longer delays were not associated with poorer outcomes. CONCLUSION: One in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease

UCL Discovery

The James Webb Space Telescope Mission

Author: Abbott Randy
Abell James S.
Abernathy Mark
Abney Faith E.
Abraham John G.
Abraham Roberto
Abul-Huda Yasin M.
Acton Scott
Adams Cynthia K.
Adams Evan
Adler David S.
Adriaensen Maarten
Aguilar Jonathan Albert
Ahmed Mansoor
Ahmed Nasif S.
Ahmed Tanjira
Alarcon Rafael Ramos
Albat Rüdeger
Albert Loïc
Alberts Stacey
Aldridge David
Allen Mary Marsha
Allen Shaune S.
Altenburg Martin
Altunc Serhat
Alvarez Jose Lorenzo
Ambrose Leslie L.
Anandakrishnan Satya M.
Andersen Gregory C.
Anderson Harry James
Anderson Jay
Anderson Kristen
Anderson Sara M.
Aprea Julio
Archer Benita J.
Arenberg Jonathan W.
Argyriou Ioannis
Arribas Santiago
Artigau Étienne
Arvai Amanda Rose
Atcheson Paul
Atkinson Charles B.
Averbukh Jesse
Aymergen Cagatay
Bacinski John J.
Baggett Wayne E.
Bagnasco Giorgio
Baker Lynn L.
Balzano Vicki Ann
Banks Kimberly A.
Baran David A.
Barker Elizabeth A.
Barrett Larry K.
Barringer Bruce O.
Barto Allison
Bast William
Baudoz Pierre
Baum Stefi
Beatty Thomas G.
Beaulieu Mathilde
Bechtold Kathryn
Beck Tracy
Beddard Megan M.
Beichman Charles
Bellagama Larry
Bely Pierre
Berger Timothy W.
Bergeron Louis E.
Bertch Maria D.
Beskow Charlotte
Betz Laura E.
Biagetti Carl P.
Birkmann Stephan
Bjorklund Kurt F.
Blackwood James D.
Blazek Ronald Paul
Blossfeld Stephen
Bluth Marcel
Boccaletti Anthony
Boegner Jr. Martin E.
Bohlin Ralph C.
Boia John Joseph
Bonaventura N.
Bond Nicholas A.
Bosley Kari Ann
Boucarut Rene A.
Bouchet Patrice
Bouwman Jeroen
Bower Gary
Bowers Ariel S.
Bowers Charles W.
Boyce Leslye A.
Boyer Christine T.
Boyer Martha L.
Boyer Michael
Boyer Robert
Bradley Larry D.
Brady Gregory R.
Brandl Bernhard R.
Brannen Judith L.
Breda David
Bremmer Harold G.
Brennan David
Bresnahan Pamela A.
Bright Stacey N.
Broiles Brian J.
Bromenschenkel Asa
Brooks Brian H.
Brooks Keira J.
Brown Bob
Brown Bruce
Brown Thomas M.
Bruce Barry W.
Bryson Jonathan G.
Bujanda Edwin D.
Bullock Blake M.
Bunker A. J.
Bureo Rafael
Burt Irving J.
Bush James Aaron
Bushouse Howard A.
Bussman Marie C.
Böker Torsten
Cabaud Olivier
Cale Steven
Calhoon Charles D.
Calvani Humberto
Canipe Alicia M.
Caputo Francis M.
Cara Mihai
Carey Larkin
Case Michael Eli
Cesari Thaddeus
Cetorelli Lee D.
Chance Don R.
Chandler Lynn
Chaney Dave
Chapman George N.
Charlot S.
Chayer Pierre
Cheezum Jeffrey I.
Chen Bin
Chen Christine H.
Cherinka Brian
Chichester Sarah C.
Chilton Zachary S.
Chittiraibalan Dharini
Clampin Mark
Clark Charles R.
Clark Kerry W.
Clark Stephanie M.
Claybrooks Edward E.
Cleveland Keith A.
Cohen Andrew L.
Cohen Lester M.
Coleman Benee L.
Colina Luis
Colón Knicole D.
Comber Brian J.
Comeau Thomas M.
Comer Thomas
Connolly Dennis C.
Conroy Kyle E.
Contos Adam R.
Contreras James
Cook Neil J.
Cooper James L.
Cooper Rachel Aviva
Correia Michael F.
Correnti Matteo
Cossou Christophe
Costanza Brian F.
Costas Maria Begoña Vila
Coulais Alain
Cox Colin R.
Coyle Ray T.
Cracraft Misty M.
Crew Keith A.
Curtis Gary J.
Cusveller Bianca
Dailey Christopher T.
Darveau-Bernier Antoine
Daugeron Frédéric
Davidson Greg S.
Davies James E.
Davis Katherine Anne
Davis Michael S.
Day Ratna
de Chambure Daniel
de Jong Pauline
De Marchi Guido
De Meester Wim
de Oliveira Catarina Alves
Dean Bruce H.
Decker John E.
del Pino Bruno Rodríguez
Delisa Amy S.
Dell Lawrence C.
Dellagatta Gail
Dembinska Franciszka
Demosthenes Sandor
Dencheva Nadezhda M.
Deneu Philippe
DePriest William W.
Deschenes Jeremy
Dethienne Nathalie
Detre Örs Hunor
Diaz Rosa Izela
Dicken Daniel
DiFelice Audrey S.
Dillman Matthew
Disharoon Maureen O.
Dixon William V.
Doggett Jesse B.
Dominguez Keisha L.
Donaldson Thomas S.
Doria-Warner Cristina M.
Doty Heather
Douglas Jr. Robert E.
Doyon René
Dressler Alan
Driggers Jennifer
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DuPrie Kimberly C.
Dupuis Jean
Durning John
Dutta Sanghamitra B.
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Eccleston Paul
Ecobichon Pascal
Egami Eiichi
Ehrenwinkler Ralf
Eisenhamer Jonathan D.
Eisenhower Michael
Eisenstein Daniel J.
Elie Michelle L.
Elliott James
Elliott Kyle Wesley
Engesser Michael
Espinoza Néstor
Etienne Odessa
Etxaluze Mireya
Evans Leah
Fabreguettes Luce
Falcolini Massimo
Falini Patrick R.
Fatig Curtis
Feeney Matthew
Feinberg Lee D.
Fels Raymond
Ferdous Nazma
Ferguson Henry C.
Ferrarese Laura
Ferreira Marie-Héléne
Ferruit Pierre
Ferry Malcolm
Filippazzo Joseph Charles
Firre Daniel
Fix Mees
Flagey Nicolas
Flanagan Kathryn A.
Fleming Scott W.
Florian Michael
Flynn James R.
Foiadelli Luca
Fontaine Mark R.
Fontanella Erin Marie
Forshay Peter Randolph
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Framarini Alexandro P.
Francisco John I.
Franck Randy
Franx Marijn
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Friend Katheryn E.
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Fu Henry
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Gaillard Lionel
Galkin Sergey
Gallagher Ben
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Gardner Jonathan P.
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Garland Dennis
Garrett Bruce Albert
Gasman Danny
Gastaud René
Gaudreau Daniel
Gauthier Peter Timothy
Geers Vincent
Geithner Paul H.
Gennaro Mario
Gerber John
Gereau John C.
Giampaoli Robert
Giardino Giovanna
Gibbons Paul C.
Gilbert Karolina
Gilman Larry
Girard Julien H.
Giuliano Mark E.
Gkountis Konstantinos
Glasse Alistair
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Gordon Karl D.
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Goudfrooij Paul
Gough Michael J.
Graham Adrian J.
Grau Christopher M.
Green Joel David
Greene Gretchen R.
Greene Thomas P.
Greenfield Perry E.
Greenhouse Matthew A.
Greve Thomas R.
Greville Edgar M.
Grimaldi Stefano
Groe Frank E.
Groebner Andrew
Grumm David M.
Grundy Timothy
Guillard Pierre
Guldalian John
Gunn Christopher A.
Gurule Anthony
Gutman Irvin Meyer
Guy Paul D.
Guyot Benjamin
Gáspár András
Güdel Manuel
Hack Warren J.
Haderlein Peter
Hagan James B.
Hagedorn Andria
Hainline Kevin
Haley Craig
Hamel Zaky El
Hami Maryam
Hamilton Forrest Clifford
Hammann Jeffrey
Hammel Heidi B.
Hanley Christopher J.
Hansen Carl August
Hardy Bruce
Harnisch Bernd
Harr Michael Hunter
Harris Pamela
Hart Jessica Ann
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Hasan Hashima
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Hashimoto Ryan
Haskins Sujee J.
Hawkins Robert Edward
Hayden Brian
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Healy Mike
Hecht Karen
Heeg Vince J.
Hejal Reem
Helm Kristopher A.
Hengemihle Nicholas J.
Henning Thomas
Henry Alaina
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Henshaw Katherine
Hernandez Scarlin
Herrington Donald C.
Heske Astrid
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Hickey David L.
Hilbert Bryan N.
Hines Dean C.
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Hirsch Michael
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Hodapp Klaus
Hodge Philip E.
Hoffman Melissa
Holfeltz Sherie T.
Holler Bryan Jason
Hoppa Jennifer Rose
Horner Scott
Howard Joseph M.
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Huber Jean M.
Hunkeler Joseph S.
Hunter Alexander
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Hurd Spencer W.
Hurst Brendan J.
Hutchings John B.
Hylan Jason E.
Ignat Luminita Ilinca
Illingworth Garth
Irish Sandra M.
Isaacs III John C.
Jackson Jr. Wallace C.
Jaffe Daniel T.
Jahic Jasmin
Jahromi Amir
Jakobsen Peter
James Bryan
James John C.
James LeAndrea Rae
Jamieson William Brian
Jandra Raymond D.
Jayawardhana Ray
Jedrzejewski Robert
Jeffers Basil S.
Jensen Peter
Joanne Egges
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Johnson Carl A.
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Johnson Timothy W.
Johnstone Doug
Jollet Delphine
Jones Danny P.
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Jue Reginald
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Justis Grant
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Kammerer Jens
Kan Samuel K.
Kanarek Graham Childs
Kao Shaw-Hong
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Karl Hermann
Kassin Susan A.
Kauffman David D.
Kavanagh Patrick
Kelley Leigh L.
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Kennedy Herbert V.
Kenny Deborah A.
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Keyes Charles D.
Khan Ali
Kidwell Richard C.
Kimble Randy A.
King James S.
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Kinzel Wayne M.
Kirk Jeffrey R.
Kirkpatrick Marc E.
Klaassen Pamela
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Knapp Bryan Adam
Knight Scott
Knollenberg Perry J.
Knutsen Daniel Mark
Koehler Robert
Koekemoer Anton M.
Kofler Earl T.
Kontson Vicki L.
Kovacs Aiden Rose
Kozhurina-Platais Vera
Krause Oliver
Kriss Gerard A.
Krist John
Kristoffersen Monica R.
Krogel Claudia
Krueger Anthony P.
Kulp Bernard A.
Kumari Nimisha
Kwan Sandy W.
Kyprianou Mark
Labador Aurora Gadiano
Labiano Álvaro
Lafrenière David
Lagage Pierre-Olivier
Laidler Victoria G.
Laine Benoit
Laird Simon
Lajoie Charles-Philippe
Lallo Matthew D.
Lam May Yen
LaMassa Stephanie Marie
Lambros Scott D.
Lampenfield Richard Joseph
Lander Matthew Ed
Langston James Hutton
Larson Kirsten
Larson Melora
LaVerghetta Robert Joseph
Law David R.
Lawrence Jon F.
Lee David W.
Lee Janice
Lee Yat-Ning Paul
Leisenring Jarron
Leveille Michael Dunlap
Levenson Nancy A.
Levi Joshua S.
Levine Marie B.
Lewis Dan
Lewis Jake
Lewis Nikole
Libralato Mattia
Lidon Norbert
Liebrecht Paula Louisa
Lightsey Paul
Lilly Simon
Lim Frederick C.
Lim Pey Lian
Ling Sai-Kwong
Link Lisa J.
Link Miranda Nicole
Lipinski Jamie L.
Litten Oi In Tam
Liu XiaoLi
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Lobmeyer Lynette
Logue Ryan M.
Long Chris A.
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Long Ilana D.
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Lotz Jennifer M.
Love-Pruitt Jennifer M.
Lubskiy Michael
Luers Edward B.
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Luevano Annetta J.
Lui Sarah Marie G. Flores
Lund III James M.
Lundquist Ray A.
Lunine Jonathan
Lynch Richard J.
López-Caniego Marcos
Lützgendorf Nora
MacDonald Alex J.
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Macias Matthew J.
Maciel Cleyciane Da Costa
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Makrygiannis Konstantinos G.
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Manjavacas Elena
Marini Andrea
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Martel André R
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Marín Macarena García
Maschmann Marc
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Maszkiewicz Michael
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McBrayer Glen A.
McCarthy Donald W.
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McClurg Taylore D.
McCoy Martin
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McLean Brian
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Meléndez Marcio
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Midwinter Calvin
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Pacifici Camilla
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Shaughnessy Bryan
Shaw Richard A.
Shay Christopher Michael
Sheehan Even
Sheth Kartik
Shih Hsin-Yi
Shivaei Irene
Siegel Noah
Sienkiewicz Matthew G.
Simmons Debra D.
Simon Bernard P.
Sirianni Marco
Sivaramakrishnan Anand
Slade Jeffrey E.
Sloan G. C.
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Slowinski Steven E.
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Smith Eric P.
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Smith Stephanie J.
Smolik John L.
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Sonneborn George
Sontag Christopher D.
Sooy Peter R.
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Southwood Dana M.
Spain Kay
Sparmo Joseph
Speer David T.
Spencer Richard
Sprofera Joseph D.
Stallcup Scott S.
Stanley Marcia K.
Stansberry John A.
Stark Christopher C.
Starr Carl W.
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Stephens Matthew A.
Stephenson Ralph J.
Stewart Alphonso C.
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Streetman Scott
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Strobele Jingping F.
Stuhlinger Martin
Stys Jeffrey Edward
Such Miguel
Sukhatme Kalyani
Sullivan Joseph F.
Sullivan Pamela C.
Sumner Sandra M.
Sun Fengwu
Sunnquist Benjamin Dale
Swade Daryl Allen
Swam Michael S.
Swenton Diane F.
Swoish Robby A.
Tamas Laszlo
Tao Andrew
Taylor David K.
Taylor Joanna M.
Teague Kelly K.
Telfer Randal C.
Temim Tea
Texter Scott C.
Thatte Deepashri G.
Thompson Christopher Lee
Thompson Linda M.
Thomson Shaun R.
Thronson Harley
Tierney C. M.
Tikkanen Tuomo
Tinnin Lee
Tippet William Thomas
Todd Connor William
Tran Hien D.
Trauger John
Trejo Edwin Gregorio
Truong Justin Hoang Vinh
Tsukamoto Christine L.
Tufail Yasir
Tumlinson Jason
Tustain Samuel
Tyra Harrison
Ubeda Leonardo
Underwood Kelli
Uzzo Michael A.
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Valenduc Frida
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van de Wetering Inge
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van Dishoeck Ewine F.
van Haarlem Remy
Van Tea Mason
Vandenbussche Bart
Vanterpool Dona D.
Vernoy Michael R.
Volk Kevin
Voorzaat Piet
Voyton Mark F.
Vydra Ekaterina
Waddy Darryl J.
Waelkens Christoffel
Wahlgren Glenn Michael
Walker Jr. Frederick E.
Wander Michel
Warfield Christine K.
Warner Gerald
Wasiak Francis C.
Wasiak Matthew F.
Wehner James
Weiler Kevin R.
Weilert Mark
Weiss Stanley B.
Wells Martyn
Welty Alan D.
Wheate Lauren
Wheeler Thomas P.
White Christy L.
Whitehouse Paul
Whiteleather Jennifer Margaret
Whitman William Russell
Williams Christina C.
Willmer Christopher N. A.
Willott Chris J.
Willoughby Scott P.
Wilson Andrew
Wilson Debra
Wilson Donna V.
Windhorst Rogier
Wislowski Emily Christine
Wolfe David J.
Wolfe Michael A.
Wolff Schuyler
Wondel Amancio
Woo Cindy
Woods Robert T.
Worden Elaine
Workman William
Wright Gillian S.
Wu Carl
Wu Chi-Rai
Wun Dakin D.
Wymer Kristen B.
Yadetie Thomas
Yan Isabelle C.
Yang Keith C.
Yates Kayla L.
Yeager Christopher R.
Yerger Ethan John
Young Erick T.
Young Gary
Yu Gene
Yu Susan
Zak Dean S.
Zeidler Peter
Zepp Robert
Zhou Julia
Zincke Christian A.
Zonak Stephanie
Zondag Elisabeth
Álvarez-Márquez Javier
Östlin Göran
Publication venue
Publication date: 10/04/2023
Field of study

Twenty-six years ago a small committee report, building on earlier studies, expounded a compelling and poetic vision for the future of astronomy, calling for an infrared-optimized space telescope with an aperture of at least

4m

. With the support of their governments in the US, Europe, and Canada, 20,000 people realized that vision as the

6.5m

James Webb Space Telescope. A generation of astronomers will celebrate their accomplishments for the life of the mission, potentially as long as 20 years, and beyond. This report and the scientific discoveries that follow are extended thank-you notes to the 20,000 team members. The telescope is working perfectly, with much better image quality than expected. In this and accompanying papers, we give a brief history, describe the observatory, outline its objectives and current observing program, and discuss the inventions and people who made it possible. We cite detailed reports on the design and the measured performance on orbit.Comment: Accepted by PASP for the special issue on The James Webb Space Telescope Overview, 29 pages, 4 figure

arXiv.org e-Print Archive

Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Author: Abbafati Cristiana
Abbas Kaja M.
Abbasi Mohammad
Abbasi-Kangevari Mohsen
Abbasifard Mitra
Abbastabar Hedayat
Abd El Razek Hassan Magdy
Abd El Razek Muhammed Magdy
Abd-Allah Foad
Abdelalim Ahmed
Abdollahi Mohammad
Abdollahpour Ibrahim
Abdulkader Rizwan Suliankatchi
Abdullah Kanaan Hamagharib
Abedi Aidin
Abedi Parisa
Abegaz Kedir Hussein
Abolhassani Hassan
Abosetugn Akine Eshete
Aboyans Victor
Abrams Elissa M.
Abreu Lucas Guimaraes
Abrigo Michael R. M.
Abu Haimed Abdulaziz Khalid
Abu-Gharbieh Eman
Abu-Raddad Laith Jamal
Abualhasan Ahmed
Abushouk Abdelrahman I.
Acebedo Alyssa
Ackerman Ilana N.
Adabi Maryam
Adair Tim
Adamu Abdu A.
Adebayo Oladimeji M.
Adedeji Isaac Akinkunmi
Adekanmbi Victor
Adelson Jaimie D.
Adeoye Abiodun Moshood
Adetokunboh Olatunji O.
Adham Davoud
Advani Shailesh M.
Afarideh Mohsen
Afshari Mahdi
Afshin Ashkan
Agardh Emilie E.
Agarwal Gina
Agasthi Pradyumna
Agesa Kareha M.
Aghaali Mohammad
Aghamir Seyed Mohammad Kazem
Agrawal Anurag
Ahmad Tauseef
Ahmadi Alireza
Ahmadi Keivan
Ahmadi Mehdi
Ahmadieh Hamid
Ahmadpour Ehsan
Ahmed Muktar Beshir
Aji Budi
Akalu Temesgen Yihunie
Akinyemi Rufus Olusola
Akinyemiju Tomi
Akombi Blessing
Akunna Chisom Joyqueenet
Al-Aly Ziyad
Al-Mekhlafi Hesham M.
Al-Raddadi Rajaa M.
Alahdab Fares
Alam Khurshid
Alam Noore
Alam Samiah
Alam Tahiya
Alanezi Fahad Mashhour
Alanzi Turki M.
Albertson Samuel B.
Alcalde-Rabanal Jacqueline Elizabeth
Alema Niguse Meles
Alemu Biresaw Wassihun
Alemu Yihun Mulugeta
Alhabib Khalid F.
Alhassan Robert Kaba
Ali Muhammad
Ali Saqib
Alicandro Gianfranco
Alijanzadeh Mehran
Alinia Cyrus
Alipour Vahid
Alizade Hesam
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Alla Francois
Allebeck Peter
Almadi Majid Abdulrahman Hamad
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Almulhim Abdulaziz M.
Alonso Jordi
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Amul Gianna Gayle Herrera
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Anderlini Deanna
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Angus Colin
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Ansari Fereshteh
Ansari Iman
Ansari-Moghaddam Alireza
Antonazzo Ippazio Cosimo
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Arab-Zozani Morteza
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Aremu Olatunde
Ariani Filippo
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Aryal Krishna K.
Arzani Afsaneh
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Atnafu Desta Debalkie
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Atre Sachin R.
Atteraya Madhu Sudhan
Ausloos Floriane
Ausloos Marcel
Avila-Burgos Leticia
Avokpaho Euripide Frinel Gbenato Arthur
Ayano Getinet
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Aynalem Getie Lake
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Azari Samad
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Bicer Burcu Kucuk
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Bijani Ali
Bikbov Boris
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Biondi Antonio
Birihane Binyam Minuye
Bisanzio Donal
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Biswas Raaj Kishore
Bitew Helen
Bjorge Tone
Bockarie Moses John
Bohlouli Somayeh
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Bojia Hunduma Amensisa
Bolla Srinivasa Rao
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Braithwaite Dejana
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Brayne Carol
Breitborde Nicholas J. K.
Breitner Susanne
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Briant Paul Svitil
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Briko Andrey Nikolaevich
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Britton Gabrielle B.
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Burkart Katrin
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Butt Zahid A.
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Cahuana-Hurtado Lucero
Cai Tianji
Callender Charlton S. K. H.
Camera Luis Alberto
Campos-Nonato Ismael R.
Cao Jackie
Car Josip
Car Lorainne Tudor
Cardenas Rosario
Carreras Giulia
Carrero Juan J.
Carvalho Felix
Castaldelli-Maia Joao Mauricio
Castaneda-Orjuela Carlos A.
Castelpietra Giulio
Castle Chris D.
Castro Emma
Castro Franz
Catala-Lopez Ferran
Causey Kate
Cederroth Christopher R.
Cercy Kelly M.
Cerin Ester
Chalek Julian
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Chang Jung-Chen
Chang Kai-Lan
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Chattu Vijay Kumar
Chaturvedi Sarika
Cherbuin Nicolas
Chimed-Ochir Odgerel
Chin Ken Lee
Chirinos-Caceres Jesus Lorenzo
Cho Daniel Youngwhan
Choi Jee-Young Jasmine
Christensen Hanne
Chu Dinh-Toi
Chung Michael T.
Chung Sheng-Chia
Cicuttini Flavia M.
Ciobanu Liliana G.
Cirillo Massimo
Cislaghi Beniamino
Classen Thomas Khaled Dwayne
Cohen Aaron J.
Collins Emma L.
Comfort Haley
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Conti Sara
Cooper Owen R.
Corso Barbara
Cortesi Paolo Angelo
Costa Vera Marisa
Cousin Ewerton
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Cross Di H.
Cross Marita
Crowe Christopher Stephen
Cruz Jessica A.
Cummins Steven
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D'Amico Emanuele
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Dai Haijiang
Dai Hancheng
Damasceno Albertino Antonio Moura
Damiani Giovanni
Dandona Lalit
Dandona Rakhi
Daneshpajouhnejad Parnaz
Dangel William James
Danielsson Anna-Karin
Dargan Paul I.
Darshan B. B.
Darwesh Aso Mohammad
Daryani Ahmad
Das Gupta Rajat
Das Neves Jose
Das Jai K.
Dash Aditya Prasad
Davey Gail
Davila-Cervantes Claudio Alberto
Davis Adrian C.
Davitoiu Dragos Virgil
Davletov Kairat
De Leo Diego
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Dean Frances E.
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Deen Amanda
Defo Barthelemy Kuate
Degenhardt Louisa
DeLang Marissa
Dellavalle Robert Paul
Demeke Feleke Mekonnen
Demoz Gebre Teklemariam
Demsie Desalegn Getnet
Denova-Gutierrez Edgar
Dereje Nebiyu Dereje
Deribe Kebede
Dervenis Nikolaos
Desai Rupak
Desalew Assefa
Dessie Getenet Ayalew
Deuba Keshab
Dharmaratne Samath Dhamminda
Dhungana Govinda Prasad
Dianatinasab Mostafa
Diaz Daniel
Dichgans Martin
Didarloo Alireza
Dingels Zachary V.
Dippenaar Ilse N.
Dirac M. Ashworth
Djalalinia Shirin
Do Hoa Thi
Dokova Klara
Doku David Teye
Dolecek Christiane
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Dorostkar Fariba
Doshi Chirag P.
Doshi Pratik P.
Doshmangir Leila
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Driscoll Tim Robert
Dubljanin Eleonora
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Duncan Bruce B.
Duraes Andre Rodrigues
Eagan Arielle Wilder
Ebrahimi Hedyeh
Edvardsson David
Effiong Andem
Ehrlich Joshua R.
El Nahas Nevine
El Sayed Iman
El Tantawi Maha
El-Jaafary Shaimaa I.
Elbarazi Iffat
Elgendy Islam Y.
Elhabashy Hala Rashad
Elsharkawy Aisha
Elyazar Iqbal R. F.
Emamian Mohammad Hassan
Emmons-Bell Sophia
Erskine Holly E.
Eshrati Babak
Eskandari Khalil
Eskandarieh Sharareh
Esmaeilnejad Saman
Esmaeilzadeh Firooz
Esteghamati Alireza
Esteghamati Sadaf
Estep Kara
Etemadi Arash
Etisso Atkilt Esaiyas
Ezekannagha Oluchi
Fanzo Jessica
Farag Tamer
Farahmand Mohammad
Faraj Anwar
Faraon Emerito Jose A.
Fareed Mohammad
Faridnia Roghiyeh
Farinha Carla Sofia e Sa
Farioli Andrea
Faris Pawan Sirwan
Faro Andre
Faruque Mithila
Farzadfar Farshad
Fattahi Nazir
Fazaeli Ali Akbar
Fazlzadeh Mehdi
Feigin Valery L.
Feldman Rachel
Fereshtehnejad Seyed-Mohammad
Fernandes Eduarda
Ferrara Giannina
Ferrara Pietro
Ferrari Alize J.
Ferreira Manuela L.
Feyissa Garumma Tolu
Filip Irina
Fischer Florian
Fisher James L.
Fitzgerald Ryan
Flohr Carsten
Flor Luisa Sorio
Foigt Nataliya A.
Folayan Morenike Oluwatoyin
Fomenkov Artem Alekseevich
Force Lisa M.
Fornari Carla
Forooshani Zahra Sadat Dibaji
Foroutan Masoud
Fox Jack T.
Francis Joel Msafiri
Frank Tahvi D.
Franklin Richard Charles
Freitas Marisa
Fu Weijia
Fukumoto Takeshi
Fukutaki Kai
Fuller John E.
Fullman Nancy
Furtado Joao M.
Gad Mohamed M.
Gaidhane Abhay Motiramji
Gakidou Emmanuela
Galles Natalie C.
Gallus Silvano
Gamkrelidze Amiran
Garcia-Basteiro Alberto L.
Gardner William M.
Geberemariyam Biniyam Sahiledengle
Gebrehiwot Abiyu Mekonnen
Gebremedhin Ketema Bizuwork
Gebremeskel Gebreamlak Gebremedhn
Gebremeskel Leake G.
Gebresillassie Begashaw Melaku
Gebreslassie Assefa Ayalew Ayalew Ayalew
Gela Jiregna Darega
Geramo Yilma Chisha Dea
Geremew Abraham
Gesesew Hailay Abrha
Gething Peter W.
Gezae Kebede Embaye
Ghadimi Maryam
Ghadiri Keyghobad
Ghaffarifar Fatemeh
Ghafourifard Mansour
Ghajar Alireza
Ghamari Farhad
Ghashghaee Ahmad
Ghiasvand Hesam
Ghith Nermin
Gholamian Asadollah
Ghosh Rakesh
Giampaoli Simona
Gilani Syed Amir
Gill Paramjit Singh
Gill Tiffany K.
Gillum Richard F.
Ginawi Ibrahim Abdelmageed
Ginindza Themba G.
Gitimoghaddam Mojgan
Giussani Giorgia
Glagn Mustefa
Glushkova Ekaterina Vladimirovna
Gnedovskaya Elena V.
Godinho Myron Anthony
Goharinezhad Salime
Golechha Mahaveer
Goli Srinivas
Gomez Ricardo Santiago
Gona Philimon N.
Gopalani Sameer Vali
Goren Emily
Gorini Giuseppe
Gorman Taren M.
Gottlich Harrison Chase
Goudarzi Houman
Goudarzian Amir Hossein
Goulart Alessandra C.
Goulart Barbara Niegia Garcia
Grada Ayman
Greaves Felix
Grivna Michal
Grosso Giuseppe
Gubari Mohammed Ibrahim Mohialdeen
Gudi Nachiket
Gugnani Harish Chander
Guimaraes Andre Luiz Sena
Guimaraes Rafael Alves
Guled Rashid Abdi
Gultie Teklemariam
Guo Gaorui
Guo Yuming
Gupta Rahul
Gupta Rajeev
Gupta Tarun
Haagsma Juanita A.
Hachinski Vladimir
Haddock Beatrix
Hafezi-Nejad Nima
Hafiz Abdul
Hagins Hailey
Haile Lydia M.
Haile Teklehaimanot Gereziher
Haj-Mirzaian Arvin
Haj-Mirzaian Arya
Hall Brian J.
Halvaei Iman
Hamadeh Randah R.
Hameed Sajid
Hamidi Samer
Hamilton Erin B.
Hammer Melanie S.
Han Chieh
Han Hannah
Handiso Demelash Woldeyohannes
Hanif Asif
Hankey Graeme J.
Hanson Sarah Wulf
Haririan Hamidreza
Haro Josep Maria
Harvey James D.
Hasaballah Ahmed I.
Hasan Md Mehedi
Hasanpoor Edris
Hasanzadeh Amir
Hashemian Maryam
Hashi Abdiwahab
Hassan Amr
Hassan Shoaib
Hassanipour Soheil
Hassankhani Hadi
Havmoeller Rasmus J.
Hawariat Feleke Gebremeskel W.
Hay Roderick J.
Hay Simon I.
Hayat Khezar
Hayoon Anna Gershberg
Heibati Behzad
Heidari Behnam
Heidari Golnaz
Heidari-Soureshjani Reza
Hendrie Delia
Henny Kiana
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Henry Nathaniel J.
Herbert Molly E.
Herrera Ana M. Mantilla
Herteliu Claudiu
Heydarpour Fatemeh
Hird Thomas R.
Ho Hung Chak
Hoek Hans W.
Hole Michael K.
Holla Ramesh
Hollingsworth Bruce
Hoogar Praveen
Hopf Kathleen Pillsbury
Horita Nobuyuki
Hosgood H. Dean
Hossain Naznin
Hosseini Mostafa
Hosseinzadeh Mehdi
Hostiuc Mihaela
Hostiuc Sorin
Househ Mowafa
Hoy Damian G.
Hsairi Mohamed
Hsiao Thomas
Hsieh Vivian Chia-Rong
Hu Guoqing
Hu Kejia
Huda Tanvir M.
Hugo Fernando N.
Humayun Ayesha
Hussain Rabia
Huynh Chantal K.
Hwang Bing-Fang
Iannucci Vincent C.
Iavicoli Ivo
Ibeneme Charles Ugochukwu
Ibitoye Segun Emmanuel
Ikeda Nayu
Ikuta Kevin S.
Il Shin Jae
Ilesanmi Olayinka Stephen
Ilic Irena M.
Ilic Milena D.
Imani-Nasab Mohammad Hasan
Inbaraj Leeberk Raja
Ippolito Helen
Iqbal Usman
Irvani Seyed Sina Naghibi
Irvine Caleb Mackay Salpeter
Islam M. Mofizul
Islam MdMohaimenul
Islam Sheikh Mohammed Shariful
Islami Farhad
Iso Hiroyasu
Ivers Rebecca Q.
Iwu Chidozie C. D.
Iwu Chinwe Juliana
Iyamu Ihoghosa Osamuyi
Jaafari Jalil
Jabbari Seyed Hossein Yahyazadeh
Jacobsen Kathryn H.
Jadidi-Niaragh Farhad
Jafarabadi Mohammad Asghari
Jafari Hussain
Jafarinia Morteza
Jahagirdar Deepa
Jahani Mohammad Ali
Jahanmehr Nader
Jakovljevic Mihajlo
Jalali Amir
Jalilian Farzad
James Spencer L.
Janjani Hosna
Janodia Manthan Dilipkumar
Javaheri Tahereh
Javidnia Javad
Jayatilleke Achala Upendra
Jeemon Panniyammakal
Jenabi Ensiyeh
Jha Ravi Prakash
Jha Vivekanand
Ji John S.
Jia Peng
Johansson Lars
John Oommen
John-Akinola Yetunde O.
Johnson Catherine Owens
Johnson Sarah Charlotte
Jonas Jost B.
Joo Tamas
Joshi Ankur
Joukar Farahnaz
Jozwiak Jacek Jerzy
Jurisson Mikk
Kabir Ali
Kabir Zubair
Kafil Hossein Samadi
Kalan Mohammad Ebrahimi
Kalani Hamed
Kalani Rizwan
Kalankesh Leila R.
Kalhor Rohollah
Kalhori Reza Pourmirza
Kamath Aruna M.
Kamiab Zahra
Kanchan Tanuj
Kapoor Neeti
Karanikolos Marina
Karch Andre
Karim Mohd Anisul
Karimi Salah Eddin
Karimi Seyed Asaad
Karimi Seyed M.
Karyani Ali Kazemi
Kasa Ayele Semachew
Kassa Getachew Mullu
Kassebaum Nicholas J.
Katikireddi Srinivasa Vittal
Kawakami Norito
Kayode Gbenga A.
Keddie Suzanne H.
Keiyoro Peter Njenga
Keller Cathleen
Kemmer Laura
Kendrick Parkes J.
Kereselidze Maia
Khader Yousef Saleh
Khafaie Morteza Abdullatif
Khalid Nauman
Khammarnia Mohammad
Khan Ejaz Ahmad
Khan Gulfaraz
Khan Maseer
Khaneghah Amin Mousavi
Khang Young-Ho
Khatab Khaled
Khater Amir M.
Khater Mona M.
Khatib Mahalaqua Nazli
Khayamzadeh Maryam
Khazaei Salman
Khazaie Habibolah
Khodayari Mohammad Taghi
Khoja Abdullah T.
Khubchandani Jagdish
Khundkar Roba
Kianipour Neda
Kieling Christian
Kim Cho-Il
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Kim Young-Eun
Kim Yun Jin
Kimokoti Ruth W.
Kinfu Yohannes
Kisa Adnan
Kisa Sezer
Kissimova-Skarbek Katarzyna
Kissoon Niranjan
Kivimaki Mika
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Knibbs Luke D.
Knight Megan
Knudsen Ann Kristin Skrindo
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Younker Theodore Patrick
Yousefi Bahman
Yousefi Zabihollah
Yousefifard Mahmoud
Yousefinezhadi Taraneh
Yousuf Abdilahi Yousuf
Yu Chuanhua
Yu Yong
Yuan Chun-Wei
Yuce Deniz
Yusefzadeh Hasan
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Zahabi Saleh Salehi
Zaidi Syed Saoud
Zaki Leila
Zaki Maysaa El Sayed
Zakzuk Josefina
Zamani Mohammad
Zamanian Maryam
Zandian Hamed
Zangeneh Alireza
Zarafshan Hadi
Zastrozhin Mikhail Sergeevich
Zewdie Kaleab Alemayehu
Zhang Jianrong
Zhang Yunquan
Zhang Zhi-Jiang
Zhao Jeff T.
Zhao Xiu-Ju George
Zhao Yingxi
Zheleva Bistra
Zheng Peng
Zhou Maigeng
Zhu Cong
Ziapour Arash
Zimsen Stephanie R. M.
Zlavog Bianca S.
Zodpey Sanjay
Publication venue
Publication date: 01/01/2020
Field of study

Background: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publicly available, and contributed data on incidence, prevalence, and mortality for a mutually exclusive and collectively exhaustive list of diseases and injuries. Methods: GBD estimates incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) due to 369 diseases and injuries, for two sexes, and for 204 countries and territories. Input data were extracted from censuses, household surveys, civil registration and vital statistics, disease registries, health service use, air pollution monitors, satellite imaging, disease notifications, and other sources. Cause-specific death rates and cause fractions were calculated using the Cause of Death Ensemble model and spatiotemporal Gaussian process regression. Cause-specific deaths were adjusted to match the total all-cause deaths calculated as part of the GBD population, fertility, and mortality estimates. Deaths were multiplied by standard life expectancy at each age to calculate YLLs. A Bayesian meta-regression modelling tool, DisMod-MR 2.1, was used to ensure consistency between incidence, prevalence, remission, excess mortality, and cause-specific mortality for most causes. Prevalence estimates were multiplied by disability weights for mutually exclusive sequelae of diseases and injuries to calculate YLDs. We considered results in the context of the Socio-demographic Index (SDI), a composite indicator of income per capita, years of schooling, and fertility rate in females younger than 25 years. Uncertainty intervals (UIs) were generated for every metric using the 25th and 975th ordered 1000 draw values of the posterior distribution. Findings: Global health has steadily improved over the past 30 years as measured by age-standardised DALY rates. After taking into account population growth and ageing, the absolute number of DALYs has remained stable. Since 2010, the pace of decline in global age-standardised DALY rates has accelerated in age groups younger than 50 years compared with the 1990–2010 time period, with the greatest annualised rate of decline occurring in the 0–9-year age group. Six infectious diseases were among the top ten causes of DALYs in children younger than 10 years in 2019: lower respiratory infections (ranked second), diarrhoeal diseases (third), malaria (fifth), meningitis (sixth), whooping cough (ninth), and sexually transmitted infections (which, in this age group, is fully accounted for by congenital syphilis; ranked tenth). In adolescents aged 10–24 years, three injury causes were among the top causes of DALYs: road injuries (ranked first), self-harm (third), and interpersonal violence (fifth). Five of the causes that were in the top ten for ages 10–24 years were also in the top ten in the 25–49-year age group: road injuries (ranked first), HIV/AIDS (second), low back pain (fourth), headache disorders (fifth), and depressive disorders (sixth). In 2019, ischaemic heart disease and stroke were the top-ranked causes of DALYs in both the 50–74-year and 75-years-and-older age groups. Since 1990, there has been a marked shift towards a greater proportion of burden due to YLDs from non-communicable diseases and injuries. In 2019, there were 11 countries where non-communicable disease and injury YLDs constituted more than half of all disease burden. Decreases in age-standardised DALY rates have accelerated over the past decade in countries at the lower end of the SDI range, while improvements have started to stagnate or even reverse in countries with higher SDI. Interpretation: As disability becomes an increasingly large component of disease burden and a larger component of health expenditure, greater research and developm nt investment is needed to identify new, more effective intervention strategies. With a rapidly ageing global population, the demands on health services to deal with disabling outcomes, which increase with age, will require policy makers to anticipate these changes. The mix of universal and more geographically specific influences on health reinforces the need for regular reporting on population health in detail and by underlying cause to help decision makers to identify success stories of disease control to emulate, as well as opportunities to improve. Funding: Bill & Melinda Gates Foundation. © 2020 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licens

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Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

Author: Abate Yohannes Habtegiorgis
Abbas Jaffar
Abbasi Madineh Akram
Abbasian Mohammadreza
Abbastabar Hedayat
Abd-Rabu Rami
Abdelmasseh Michael
Abdollahi Mohammad
Abdollahi Mozhan
Abdollahifar Mohammad-Amin
Abdulah Deldar Morad
Abdullahi Auwal
Abedi Aidin
Abedi Vida
Abeldaño Zuñiga Roberto Ariel
Abidi Hassan
Abiodun Olumide
Aboagye Richard Gyan
Abolhassani Hassan
Aboyans Victor
Abrha Woldu Aberhe
Abu-Gharbieh Eman
Abualhasan Ahmed
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Adekiya Tayo Alex
Adikusuma Wirawan
Adnani Qorinah Estiningtyas Sakilah
Adra Saryia
Afework Tsion
Afolabi Aanuoluwapo Adeyimika
Afraz Ali
Afzal Saira
Aghamiri Shahin
Agodi Antonella
Agyemang-Duah Williams
Ahinkorah Bright Opoku
Ahmad Aqeel
Ahmad Danish
Ahmad Sajjad
Ahmadzade Amir Mahmoud
Ahmed Ali
Ahmed Ayman
Ahmed Haroon
Ahmed Jivan Qasim
Ahmed Luai A
Ahmed Muktar Beshir
Ahmed Syed Anees
Ajami Marjan
Aji Budi
Ajumobi Olufemi
Akade Seyed Esma'il
Akbari Morteza
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Akhlaghi Shiva
Akinosoglou Karolina
Akinyemi Rufus Olusola
Akonde Maxwell
Al Hasan Syed Mahfuz
AL-Ahdal Tareq Mohammed Ali
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Ali Abid
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Ali Liaqat
Ali Mohammed Usman
Ali Musa Mohammed
Ali Rafat
Ali Shahid
Ali Syed Shujait Shujait
Ali Zahid
Alif Sheikh Mohammad
Alimohamadi Yousef
Aliyi Ahmednur Adem
Aljofan Mohamad
Aljunid Syed Mohamed
Alladi Suvarna
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Anderson David B
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Anwer Razique
Arafat Mosab
Aravkin Aleksandr Y
Areda Demelash
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Artamonov Anton A
Artanti Kurnia Dwi
Aruleba Raphael Taiwo
Asadi-Pooya Ali A
Asena Tilahun Ferede
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Atalell Kendalem Asmare
Athari Seyyed Shamsadin
Atinafu Bantalem Tilaye Tilaye
Atorkey Prince
Atout Maha Moh'd Wahbi
Atreya Alok
Aujayeb Avinash
Avan Abolfazl
Ayala Quintanilla Beatriz Paulina
Ayatollahi Haleh
Ayinde Olatunde O
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Babaei Mahsa
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Badiye Ashish D
Baghdadi Soroush
Bagherieh Sara
Bai Ruhai
Baig Atif Amin
Balakrishnan Senthilkumar
Balalla Shivanthi
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Banach Maciej
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Banerjee Indrajit
Baran Mehmet Firat
Barboza Miguel A
Barchitta Martina
Bardhan Mainak
Barker-Collo Suzanne Lyn
Barrow Amadou
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Bashiru Hameed Akande
Basiru Afisu
Basso João Diogo
Basu Sanjay
Batiha Abdul-Monim Mohammad
Batra Kavita
Baune Bernhard T
Bedi Neeraj
Begde Ahmet
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Behnam Babak
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Berice Betyna
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Beyene Kebede A
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Bhangdia Kayleigh
Bhardwaj Nikha
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Bhargava Ashish
Bhaskar Sonu
Bhat Ajay Nagesh
Bhat Vivek
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Bhatti Jasvinder Singh
Bhatti Rajbir
Bijani Ali
Bikbov Boris
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Biswas Atanu
Bitaraf Saeid
Bitra Veera R
Bjørge Tone
Bodolica Virginia
Bodunrin Aadam Olalekan
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Braithwaite Dejana
Brayne Carol
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Brown Julie
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Buonsenso Danilo
Burkart Katrin
Burns Richard A
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Butt Nadeem Shafique
Butt Zahid A
Bärnighausen Till Winfried
Béjot Yannick
Cabral Lucas Scotta
Caetano dos Santos Florentino Luciano
Calina Daniela
Campos-Nonato Ismael R
Cao Bochen
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Carabin Hélène
Carreras Giulia
Carvalho Andre F
Castañeda-Orjuela Carlos A
Casulli Adriano
Catalá-López Ferrán
Catapano Alberico L
Cavallera Vanessa
Caye Arthur
Cegolon Luca
Cenderadewi Muthia
Cerin Ester
Chacón-Uscamaita Pamela R Uscamaita
Chan Jeffrey Shi Kai
Chanie Gashaw Sisay
Charan Jaykaran
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Chekol Abebe Endeshaw
Chen Hui
Chen Jianqi
Chi Gerald
Chichagi Fatemeh
Chidambaram Saravana Babu
Chimoriya Ritesh
Ching Patrick R
Chitheer Abdulaal
Chong Yuen Yu
Chopra Hitesh
Choudhari Sonali Gajanan
Chowdhury Enayet Karim
Chowdhury Rajiv
Christensen Hanne
Chu Dinh-Toi
Chukwu Isaac Sunday
Chung Eric
Coberly Kaleb
Columbus Alyssa
Comachio Josielli
Conde Joao
Cortesi Paolo Angelo
Costa Vera Marisa
Cousin Ewerton
Couto Rosa A S
Criqui Michael H
Cruz-Martins Natália
Cárdenas Rosario
D'Amico Emanuele
Dabbagh Ohadi Mohammad Amin
Dadana Sriharsha
Dadras Omid
Dai Xiaochen
Dai Zhaoli
Danawi Hadi A
Dandona Lalit
Dandona Rakhi
Darwish Amira Hamed
Das Saswati
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Dascalu Ana Maria
Dash Nihar Ranjan
Dashti Mohsen
De la Hoz Fernando Pio
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De Leo Diego
Dean Frances E
Dehghan Amin
Dehghan Azizallah
Dejene Hiwot
Demant Daniel
Demetriades Andreas K
Demissie Solomon
Deng Xinlei
Desai Hardik Dineshbhai
Devanbu Vinoth Gnana Chellaiyan
Dhama Kuldeep
Dharmaratne Samath Dhamminda
Dhimal Meghnath
Dias da Silva Diana
Diaz Daniel
Dibas Mahmoud
Ding Delaney D
Dinu Monica
Dirac M Ashworth
Diress Mengistie
Do Thanh Chi
Do Thao Huynh Phuong
Doan Khanh Duy Khanh
Dodangeh Milad
Doheim Mohamed Fahmy
Dokova Klara Georgieva
Dongarwar Deepa
Dsouza Haneil Larson
Dua Tarun
Dube John
Duraisamy Senbagam
Durojaiye Oyewole Christopher
Dutta Sulagna
Dziedzic Arkadiusz Marian
Edinur Hisham Atan
Eissazade Negin
Ekholuenetale Michael
Ekundayo Temitope Cyrus
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Elbarazi Iffat
Elemam Noha Mousaad
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Elilo Legesse Tesfaye
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Elsohaby Ibrahim
Emamverdi Mehdi
Emeto Theophilus I
Endres Matthias
Esezobor Christopher Imokhuede
Eskandarieh Sharareh
Fadaei Abdolmajid
Fagbamigbe Adeniyi Francis
Fahim Ayesha
Faramarzi Ali
Fares Jawad
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Faro Andre
Farzadfar Farshad
Fatehizadeh Ali
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Fathi Saeid
Fatima Syeda Anum Fatima
Feigin Valery L
Feizkhah Alireza
Fereshtehnejad Seyed-Mohammad
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Ferreira Nuno
Fetensa Getahun
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Force Lisa M
Fornari Arianna
Foroutan Behzad
Fukumoto Takeshi
Gadanya Muktar A
Gaidhane Abhay Motiramji
Galali Yaseen
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Gandhi Aravind P
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Garg Naval
Gau Shuo-Yan
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Gebre Teshome
Gebrehiwot Mesfin
Gebremeskel Gebreamlak Gebremedhn
Gebreslassie Haftay Gebremedhin
Getacher Lemma
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Ghadirian Fataneh
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Ghanbari Reza
Ghasemi MohammadReza
Ghazy Ramy Mohamed
Ghimire Sailaja
Gholami Ali
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Ghotbi Elena
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Gill Paramjit Singh
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Guan Bin
Guarducci Giovanni
Guicciardi Stefano
Gunawardane Damitha Asanga
Guo Hanbing
Gupta Bhawna
Gupta Rajeev
Gupta Sapna
Gupta Veer Bala
Gupta Vivek Kumar
Gutiérrez Reyna Alma
Habibzadeh Farrokh
Hachinski Vladimir
Haddadi Rasool
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Haile Teklehaimanot Gereziher
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Hanifi Nasrin
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Hannan Md. Abdul
Hao Junwei
Harapan Harapan
Hareru Habtamu Endashaw
Hargono Arief
Harlianto Netanja I.
Haro Josep Maria
Hartman Nicholas Nathaniel
Hasaballah Ahmed I.
Hasan Faizul
Hasani Hamidreza
Hasanian Mohammad
Hassan Amr
Hassan Shoaib
Hassanipour Soheil
Hassankhani Hadi
Hassen Mohammed Bheser
Haubold Johannes
Hay Simon I
Hayat Khezar
Hegazy Mohamed I
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Heidari Mohammad
Heidari-Soureshjani Reza
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Holla Ramesh
Hopf Kathleen Pillsbury
Horita Nobuyuki
Hossain Md Mahbub
Hossain Md. Belal
Hossain Sahadat
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Hostiuc Sorin
Hu Chengxi
Huang Junjie
Huda Md. Nazmul
Hussain Javid
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Hwang Bing-Fang
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Ilaghi Mehran
Ilesanmi Olayinka Stephen
Ilic Irena M
Ilic Milena D
Immurana Mustapha
Iravanpour Farideh
Islam Sheikh Mohammed Shariful
Ismail Faisal
Iso Hiroyasu
Isola Gaetano
Iwagami Masao
Iwu Chidozie C D
Iyer Mahalaxmi
Jaan Ali
Jacob Louis
Jadidi-Niaragh Farhad
Jafari Mahboobeh
Jafarinia Morteza
Jafarzadeh Abdollah
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Jahanmehr Nader
Jahrami Haitham
Jaiswal Abhishek
Jakovljevic Mihajlo
Jamora Roland Dominic G
Jana Somnath
Javadi Nilofer
Javed Saad
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Jayaram Shubha
Jiang Heng
Johnson Catherine Owens
Johnson Walter D
Jokar Mohammad
Jonas Jost B
Joseph Abel
Joseph Nitin
Joshua Charity Ehimwenma
Jürisson Mikk
Kabir Ali
Kabir Zubair
Kabito Gebisa Guyasa
Kadashetti Vidya
Kafi Fatemeh
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Kalantar Farnaz
Kaliyadan Feroze
Kamath Ashwin
Kamath Sagarika
Kanchan Tanuj
Kandel Amit
Kandel Himal
Kanmodi Kehinde Kazeem
Karajizadeh Mehrdad
Karami Jafar
Karanth Shama D
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Karimi Behnagh Arman
Karimi Aliasghar
Karimi Hanie
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Keller Cathleen
Keykhaei Mohammad
Khadembashiri Mohammad Amin
Khader Yousef Saleh
Khafaie Morteza Abdullatif
Khajuria Himanshu
Khalaji Amirmohammad
Khamesipour Faham
Khammarnia Mohammad
Khan Suheb Mahammed Ziauddin
Khan Maseer
Khan Moien AB
Khan Yusra H
Khanmohammadi Shaghayegh
Khanna Tripti
Khatab Khaled
Khatatbeh Haitham
Khatatbeh Moawiah Mohammad
Khateri Sorour
Khatib Mahalaqua Nazli
Khayat Kashani Hamid Reza
Khonji Mohammad Saeid
khorashadizadeh Fatemeh
Khormali Moein
Khubchandani Jagdish
Kian Saeid
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Kim Jihee
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Kim Yun Jin
Kimokoti Ruth W
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Kochhar Sonali
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Kompani Farzad
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Kosen Soewarta
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Koyanagi Ai
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Krishan Kewal
Krishnamoorthy Vijay
Kuate Defo Barthelemy
Kuddus Md Abdul
Kumar Ashish
Kumar G Anil
Kumar Manasi
Kumar Nithin
Kumsa Netsanet Bogale
Kundu Satyajit
Kurniasari Maria Dyah
Kusuma Dian
Kuttikkattu Ambily
Kyu Hmwe Hmwe
La Vecchia Carlo
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Lahariya Chandrakant
Laksono Tri
Lal Dharmesh Kumar
Lallukka Tea
Lami Faris Hasan
Landires Iván
Langguth Berthold
Lasrado Savita
Latief Kamaluddin
Latifinaibin Kaveh
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Laurens Matthew B
Lawal Basira Kankia
Le Long Khanh Dao
Le Thao Thi Thu
Ledda Caterina
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Lee Wei-Chen
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Lopes Graciliana
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Lucchetti Giancarlo
Lutzky Saute Ricardo
Lám Judit
Ma Zheng Feei
Mabrok Mahmoud
Machoy Monika
Madadizadeh Farzan
Magdy Abd El Razek Mohammed
Maghazachi Azzam A
Maghbouli Nastaran
Mahjoub Soleiman
Mahmoudi Morteza
Majeed Azeem
Malagón-Rojas Jeadran N.
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Malhotra Kashish
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Mallhi Tauqeer Hussain
Malta Deborah Carvalho
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Mansouri Vahid
Mansournia Mohammad Ali
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Maroufi Seyed Farzad
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Martini Santi
Martins-Melo Francisco Rogerlândio
Martorell Miquel
Marzo Roy Rillera
Massano João
Mathangasinghe Yasith
Mathews Elezebeth
Maude Richard James
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Mazaheri Maryam
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Mi Tianyue
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Mirzaei Mehdi
Misganaw Awoke
Misra Sanjeev
Mithra Prasanna
Mizana Biru Abdissa
Moberg Madeline E
Mohamadkhani Ashraf
Mohamed Nouh Saad
Mohammadi Esmaeil
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Mohammed Mustapha
Mohammed Salahuddin
Mohammed Shafiu
Mohan Syam
Mojiri-forushani Hoda
Moka Nagabhishek
Mokdad Ali H
Molinaro Sabrina
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Montazeri Fateme
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Moradi Yousef
Moradi-Lakeh Maziar
Moraga Paula
Morovatdar Negar
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Mosapour Abbas
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Muccioli Lorenzo
Mughal Faraz
Mukoro George Duke
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Muthu Sathish
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Naik Ganesh R
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Nair Tapas Sadasivan
Najmuldeen Hastyar Hama Rashid
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Nayak Biswa Prakash
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Negaresh Mohammad
Negash Hadush
Negoi Ionut
Negoi Ruxandra Irina
Negru Serban Mircea
Nejadghaderi Seyed Aria
Nematollahi Mohammad Hadi
Nesbit Olivia D
Newton Charles Richard James
Nguyen Dang H
Nguyen Hau Thi Hien
Nguyen Hien Quang
Nguyen Ngoc-Trinh Thi
Nguyen Phat Tuan
Nguyen Van Thanh
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Nichols Emma
Nikolouzakis Taxiarchis Konstantinos
Niranjan Vikram
Nnyanzi Lawrence Achilles
Noman Efaq Ali
Noroozi Nafise
Norrving Bo
Noubiap Jean Jacques
Nri-Ezedi Chisom Adaobi
Ntaios George
Nurrika Dieta
Nuñez-Samudio Virginia
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Oancea Bogdan
Odetokun Ismail A
Ogunsakin Ropo Ebenezer
Oguta James Odhiambo
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Okekunle Akinkunmi Paul
Okonji Osaretin Christabel
Okwute Patrick Godwin
Olagunju Andrew T
Olaiya Muideen Tunbosun
Olana Matifan Dereje
Olatubi Matthew Idowu
Oliveira Gláucia Maria Moraes
Olufadewa Isaac Iyinoluwa
Olusanya Bolajoko Olubukunola
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Owolabi Mayowa O
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Pacheco-Barrios Kevin
Padubidri Jagadish Rao
Pal Pramod Kumar
Palange Padmavali Nanaji
Palladino Claudia
Palladino Raffaele
Palma-Alvarez Raul Felipe
Pan Feng
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Pandey Ashok
Pandian Jeyaraj Durai
Pangaribuan Helena Ullyartha
Pantazopoulos Ioannis
Pardhan Shahina
Parija Pragyan Paramita
Parikh Romil R
Park Seoyeon
Parthasarathi Ashwaghosha
Pashaei Ava
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Pawar Shrikant
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Pensato Umberto
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Pereira Jeevan
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Petcu Ionela-Roxana
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Poddighe Dimitri
Polat Burcu
Poluru Ramesh
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Poudel Govinda Raj
Pouramini Alireza
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Pourfridoni Mohammad
Pourtaheri Naeimeh
Prakash Peralam Yegneswaran
Prakash Sanjay
Prakash V
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Pritchett Natalie
Purnobasuki Hery
Qasim Nameer Hashim
Qattea Ibrahim
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Raee Pourya
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Rahman Md Obaidur
Rahman Mohammad Hifz Ur
Rahman Mosiur
Rahman Muhammad Aziz
Rahmani Youshanlouei Hamed
Rahmani Amir Masoud
Rahmani Shayan
Rahmati Masoud
Raj Moolambally Sheetal
Rajabpour-Sanati Ali
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Ramasubramani Premkumar
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Rancic Nemanja
Rao Indu Ramachandra
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Rashedi Vahid
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Rashidi Mohammad-Mahdi
Rasouli-Saravani Ashkan
Rawaf Salman
Razo Christian
Redwan Elrashdy Moustafa Mohamed
Rekabi Bana Atefe
Remuzzi Giuseppe
Rezaei Nazila
Rezaei Negar
Rezaei Nima
Rezaeian Mohsen
Rhee Taeho Gregory
Riad Abanoub
Robinson Stephen R
Rodrigues Mónica
Rodriguez Jefferson Antonio Buendia
Roever Leonardo
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Saadatian Zahra
Saber Korosh
SaberiKamarposhti Morteza
Sacco Simona
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Sadeghi Erfan
Sadeghian Saeid
Saeed Umar
Saeed Usman
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Safi Sher Zaman
Sagar Rajesh
Sagoe Dominic
Saheb Sharif-Askari Fatemeh
Saheb Sharif-Askari Narjes
Sahebkar Amirhossein
Sahoo Soumya Swaroop
Sahraian Mohammad Ali
Sajedi Seyed Aidin
Sakshaug Joseph W
Saleh Mohamed A
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Santri Ichtiarini Nurullita
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Sarveazad Arash
Satpathy Maheswar
Saylan Mete
Sayyah Mehdi
Scarmeas Nikolaos
Schiess Nicoline
Schlaich Markus P
Schuermans Art
Schwarzinger Michaël
Schwebel David C
Seeher Katrin Maria
Selvaraj Siddharthan
Sendekie Ashenafi Kibret
Sengupta Pallav
Senthilkumaran Subramanian
Serban Dragos
Sergindo Mihretu Tagesse
Servili Chiara
Sethi Yashendra
SeyedAlinaghi SeyedAhmad
Seylani Allen
Shabani Mohammad
Shabany Maryam
Shafie Mahan
Shahabi Saeed
Shahbandi Ataollah
Shahid Samiah
Shahraki-Sanavi Fariba
Shahsavari Hamid R
Shahwan Moyad Jamal
Shaikh Masood Ali
Shaji KS
Sham Sunder
Shama Adisu Tafari T
Shamim Muhammad Aaqib
Shams-Beyranvand Mehran
Shamsi Mohammad Anas
Shanawaz Mohd
Sharath Medha
Sharfaei Sadaf
Sharifan Amin
Sharma Manoj
Sharma Rajesh
Shashamo Bereket Beyene
Shayan Maryam
Sheikhi Rahim Ali
Shekhar Shashank
Shen Jiabin
Shenoy Suchitra M
Shetty Pavanchand H
Shiferaw Desalegn Shiferaw
Shigematsu Mika
Shiri Rahman
Shittu Aminu
Shivakumar K M
Shokri Fereshteh
Shool Sina
Shorofi Seyed Afshin
Shrestha Sunil
Siankam Tankwanchi Akhenaten Benjamin
Siddig Emmanuel Edwar
Sigfusdottir Inga Dora
Silva João Pedro
Silva Luís Manuel Lopes Rodrigues
Sinaei Ehsan
Singh Balbir Bagicha
Singh Garima
Singh Paramdeep
Singh Surjit
Sirota Sarah Brooke
Sivakumar Shravan
Sohag Abdullah Al Mamun
Solanki Ranjan
Soleimani Hamidreza
Solikhah Solikhah
Solomon Yerukneh
Solomon Yonatan
Song Suhang
Song Yimeng
Sotoudeh Houman
Spartalis Michael
Stark Benjamin A
Starnes Joseph R
Starodubova Antonina V
Stein Dan J
Steiner Timothy J
Steinmetz Jaimie D
Stovner Lars Jacob
Suleman Muhammad
Suliankatchi Abdulkader Rizwan
Sultana Abida
Sun Jing
Sunkersing David
Sunny Angel
Susianti Hani
Swain Chandan Kumar
Szeto Mindy D
Tabarés-Seisdedos Rafael
Tabatabaei Seyyed Mohammad
Tabatabai Shima
Tabish Mohammad
Taheri Majid
Tahvildari Azin
Tajbakhsh Ardeshir
Tampa Mircea
Tamuzi Jacques JL Lukenze
Tan Ker-Kan
Tang Haosu
Tareke Minale
Tarigan Ingan Ukur
Tat Nathan Y
Tat Vivian Y
Tavakoli Oliaee Razieh
Tavangar Seyed Mohammad
Tavasol Arian
Tefera Yibekal Manaye
Tehrani-Banihashemi Arash
Temesgen Worku Animaw
Temsah Mohamad-Hani
Teramoto Masayuki
Tesfaye Amensisa Hailu
Tesfaye Edosa Geta
Tesler Riki
Thakali Ocean
Thangaraju Pugazhenthan
Thapa Rajshree
Thapar Rekha
Thomas Nikhil Kenny
Thrift Amanda G
Ticoalu Jansje Henny Vera
Tillawi Tala
Toghroli Razie
Tonelli Marcello
Tovani-Palone Marcos Roberto
Traini Eugenio
Tran Nghia Minh
Tran Ngoc-Ha
Tran Phu Van
Tromans Samuel Joseph
Truelsen Thomas Clement
Truyen Thien Tan Tri Tai
Tsatsakis Aristidis
Tsegay Guesh Mebrahtom
Tsermpini Evangelia Eirini
Tualeka Abdul Rohim
Tufa Derara Girma
Ubah Chukwudi S
Udoakang Aniefiok John
Ulhaq Inam
Umair Muhammad
Umakanthan Srikanth
Umapathi Krishna Kishore
Unim Brigid
Unnikrishnan Bhaskaran
Vaithinathan Asokan Govindaraj
Vakilian Alireza
Valadan Tahbaz Sahel
Valizadeh Rohollah
Van den Eynde Jef
Vart Priya
Varthya Shoban Babu
Vasankari Tommi Juhani
Vaziri Siavash
Vellingiri Balachandar
Venketasubramanian Narayanaswamy
Verras Georgios-Ioannis
Vervoort Dominique
Villafañe Jorge Hugo
Villani Leonardo
Vinueza Veloz Andres Fernando
Viskadourou Maria
Vladimirov Sergey Konstantinovitch
Vlassov Vasily
Volovat Simona Ruxandra
Vos Theo
Vu Loc Tri
Vujcic Isidora S
Wagaye Birhanu
Waheed Yasir
Wahood Waseem
Walde Mandaras Tariku
Wang Fang
Wang Shu
Wang Yanzhong
Wang Yuan-Pang
Waqas Muhammad
Waris Abdul
Weerakoon Kosala Gayan
Weintraub Robert G
Weldemariam Abrha Hailay
Westerman Ronny
Whisnant Joanna L
Wickramasinghe Dakshitha Praneeth
Wickramasinghe Nuwan Darshana
Willekens Barbara
Wilner Lauren B
Winkler Andrea Sylvia
Wolfe Charles D A
Wu Ai-Min
Wulf Hanson Sarah
Xu Suowen
Xu Xiaoyue
Yadollahpour Ali
Yaghoubi Sajad
Yahya Galal
Yamagishi Kazumasa
Yang Lin
Yano Yuichiro
Yao Yao
Yehualashet Sisay Shewasinad
Yeshaneh Alex
Yesiltepe Metin
Yi Siyan
Yiğit Arzu
Yiğit Vahit
Yon Dong Keon
Yonemoto Naohiro
You Yuyi
Younis Mustafa Z
Yu Chuanhua
Yusuf Hadiza
Zadey Siddhesh
Zahedi Mohammad
Zakham Fathiah
Zaki Nazar
Zali Alireza
Zamagni Giulia
Zand Ramin
Zandieh Ghazal G Z
Zangiabadian Moein
Zarghami Amin
Zastrozhin Mikhail Sergeevich
Zeariya Mohammed G M
Zegeye Zelalem Banjaw
Zeukeng Francis
Zhai Chunxia
Zhang Chen
Zhang Haijun
Zhang Yunquan
Zhang Zhi-Jiang
Zhao Hanqing
Zhao Yang
Zheng Peng
Zhou Hengxing
Zhu Bin
Zhumagaliuly Abzal
Zielińska Magdalena
Zikarg Yossef Teshome
Zoladl Mohammad
Ärnlöv Johan
Publication venue: Elsevier
Publication date: 01/04/2024
Field of study

BackgroundDisorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous publications from the Global Burden of Disease, Injuries, and Risk Factor Study estimated the burden of 15 neurological conditions in 2015 and 2016, but these analyses did not include neurodevelopmental disorders, as defined by the International Classification of Diseases (ICD)-11, or a subset of cases of congenital, neonatal, and infectious conditions that cause neurological damage. Here, we estimate nervous system health loss caused by 37 unique conditions and their associated risk factors globally, regionally, and nationally from 1990 to 2021.MethodsWe estimated mortality, prevalence, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life-years (DALYs), with corresponding 95% uncertainty intervals (UIs), by age and sex in 204 countries and territories, from 1990 to 2021. We included morbidity and deaths due to neurological conditions, for which health loss is directly due to damage to the CNS or peripheral nervous system. We also isolated neurological health loss from conditions for which nervous system morbidity is a consequence, but not the primary feature, including a subset of congenital conditions (ie, chromosomal anomalies and congenital birth defects), neonatal conditions (ie, jaundice, preterm birth, and sepsis), infectious diseases (ie, COVID-19, cystic echinococcosis, malaria, syphilis, and Zika virus disease), and diabetic neuropathy. By conducting a sequela-level analysis of the health outcomes for these conditions, only cases where nervous system damage occurred were included, and YLDs were recalculated to isolate the non-fatal burden directly attributable to nervous system health loss. A comorbidity correction was used to calculate total prevalence of all conditions that affect the nervous system combined.FindingsGlobally, the 37 conditions affecting the nervous system were collectively ranked as the leading group cause of DALYs in 2021 (443 million, 95% UI 378–521), affecting 3·40 billion (3·20–3·62) individuals (43·1%, 40·5–45·9 of the global population); global DALY counts attributed to these conditions increased by 18·2% (8·7–26·7) between 1990 and 2021. Age-standardised rates of deaths per 100 000 people attributed to these conditions decreased from 1990 to 2021 by 33·6% (27·6–38·8), and age-standardised rates of DALYs attributed to these conditions decreased by 27·0% (21·5–32·4). Age-standardised prevalence was almost stable, with a change of 1·5% (0·7–2·4). The ten conditions with the highest age-standardised DALYs in 2021 were stroke, neonatal encephalopathy, migraine, Alzheimer's disease and other dementias, diabetic neuropathy, meningitis, epilepsy, neurological complications due to preterm birth, autism spectrum disorder, and nervous system cancer.InterpretationAs the leading cause of overall disease burden in the world, with increasing global DALY counts, effective prevention, treatment, and rehabilitation strategies for disorders affecting the nervous system are needed

Keele Research Repository

The impact of Measles-Rubella vaccination on the morbidity and mortality from Congenital Rubella Syndrome in 92 countries

Author: Kombich JJ
Mao B
Saad de Owens C
Publication venue: 'Informa UK Limited'
Publication date
Field of study

Crossref

Important stages in the development of different layers and areas of sporoderm in angiosperms

Author: AT Romero
C Clement
DE Stone
G El-Gazaly
H Zolala
HT Horner
JM Osborn
JR Rowley
JR Rowley
JR Rowly
JU Jimenez
M Takahashi
M Takahashi
M Takahashi
M Takahashi
M Weber
ML Taylor
MS Zavada
MW Hess
MW Hess
N Firon
N Firon
N Gabaraeva
N Gabaraeva
N Gabaraeva
N Gabaraeva
N Gabaraeva
NI Gabaraeva
NI Gabaraeva
NI Gabaraeva
NI Gabarayeva
NP Matveeva
NR Meier-Melikyan
OA Volkova
PL Polowick
S. V. Polevova
SB Saad-Limam
SJ Owens
SS Kreunen
T Ariizumi
Publication venue: 'Pleiades Publishing Ltd'
Publication date
Field of study

Crossref