310 research outputs found

    Explorations, Vol. 2, No. 2

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    Cover: The painting reproduced on the cover is an oil on canvas entitled “Konrad Oberhuber’s Visit to Compass Harbor, Maine, ” by Michael Lewis, 1985. Lewis is Professor of Art at the University of Maine at Orono. ©Michael Lewis, 1985 Articles include: The Gulf of Maine: A Sea Beside a Sea, by Kathleen Lignell The Gulf of Maine Littoral world of promise, by Carole J. Bombard for David Sanger Marine Worms Worth Fifteen Dollars Each? by David Dean Free Trade, Not Trade War, by James A. Wilson Inner Space—The Gulf of Maine: its history and future for research, by Robert S. Steneck The Shape of Mud and Its Importance to Marine Animals, by Les Watling The Humble Herring gold-plated sardine, by David K. Stevenson Seismic Profiling: The Search for the Submerged Geological Record in the Gulf of Maine, by Daniel F. Belknap and Joseph T. Kelley Our Cover Artist: Michael Lewis In the Classroom, by Michael Brody Nobody Told the Bumblebee He Couldn\u27t Fly, by Herbert Hidu The Tie That Binds: technology and research, by Robert S. Steneck Diet Developments for the Maine Lobster, by Robert Bayer A Wet Desert: secrets of the salt marsh, by Gary M. King Maine Marshes, by George L. Jacobson Mya Arenaria: return of the clam, by Devon Phillips CES: commitment and action, by Devon Phillips EPSCoR benthic research, by Lawrence M. Mayer In the Field of Researc

    The effect of hypothermia on influx of leukocytes in the digital lamellae of horses with oligofructose-induced laminitis

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    Sepsis-related laminitis (SRL) is a common complication in the septic/endotoxemic critically-ill equine patient, in which lamellar injury and failure commonly lead to crippling distal displacement of the distal phalanx. Similar to organ injury in human sepsis, lamellar injury in SRL has been associated with inflammatory events, including the influx of leukocytes into the lamellar tissue and markedly increased expression of a wide array of inflammatory mediators at the onset of Obel grade 1 (OG1) laminitis. The only treatment reported both clinically and experimentally to protect the lamellae in SRL, local hypothermia (“cryotherapy”), has been demonstrated to effectively inhibit lamellar expression of multiple inflammatory mediators when initiated at the time of administration of a carbohydrate overload in experimental models of SRL. However, the effect of hypothermia on leukocyte influx into affected tissue has not been assessed. We hypothesized that cryotherapy inhibits leukocyte emigration into the digital lamellae in SRL. Immunohistochemical staining using leukocyte markers MAC387 (marker of neutrophils, activated monocytes) and CD163 (monocyte/macrophage-specific marker) was performed on archived lamellar tissue samples from an experimental model of SRL in which one forelimb was maintained at ambient temperature (AMB) and one forelimb was immersed in ice water (ICE) immediately following enteral oligofructose administration (10\ua0g/kg, n\ua0=\ua014 horses). Lamellae were harvested at 24\ua0h post-oligofructose administration (DEV, n\ua0=\ua07) or at the onset of OG1 laminitis (OG1, n\ua0=\ua07). Both MAC387-positive and CD163-positive cells were counted by a single blinded investigator on images [n\ua0=\ua010 (40× fields/digit for MAC387 and 20\ua0x fields/digit for CD163)] obtained using Aperio microscopy imaging analysis software. Data were assessed for normality and analyzed with a paired t-test and one-way ANOVA with significance set at p\ua

    Measurements of branching fraction ratios and CP-asymmetries in suppressed B^- -> D(-> K^+ pi^-)K^- and B^- -> D(-> K^+ pi^-)pi^- decays

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    We report the first reconstruction in hadron collisions of the suppressed decays B^- -> D(-> K^+ pi^-)K^- and B^- -> D(-> K^+ pi^-)pi^-, sensitive to the CKM phase gamma, using data from 7 fb^-1 of integrated luminosity collected by the CDF II detector at the Tevatron collider. We reconstruct a signal for the B^- -> D(-> K^+ pi^-)K^- suppressed mode with a significance of 3.2 standard deviations, and measure the ratios of the suppressed to favored branching fractions R(K) = [22.0 \pm 8.6(stat)\pm 2.6(syst)]\times 10^-3, R^+(K) = [42.6\pm 13.7(stat)\pm 2.8(syst)]\times 10^-3, R^-(K)= [3.8\pm 10.3(stat)\pm 2.7(syst]\times 10^-3, as well as the direct CP-violating asymmetry A(K) = -0.82\pm 0.44(stat)\pm 0.09(syst) of this mode. Corresponding quantities for B^- -> D(-> K^+ pi^-)pi^- decay are also reported.Comment: 8 pages, 1 figure, accepted by Phys.Rev.D Rapid Communications for Publicatio

    Search for new physics with dijet angular distributions in proton-proton collisions at root S = 13 TeV

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    Search for narrow resonances in dilepton mass spectra in proton-proton collisions at root s=13 TeV and combination with 8 TeV data

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    Search for R-parity violating supersymmetry with displaced vertices in proton-proton collisions at root s=8 TeV

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    Observation of Charge-Dependent Azimuthal Correlations in p-Pb Collisions and Its Implication for the Search for the Chiral Magnetic Effect

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    Search for B_s --> mu+mu- and B_d --> mu+mu- Decays with CDF II

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    A search has been performed for B_s --> mu+mu- and B_d --> mu+mu- decays using 7/fb of integrated luminosity collected by the CDF II detector at the Fermilab Tevatron collider. The observed number of B_d candidates is consistent with background-only expectations and yields an upper limit on the branching fraction of BF(B_d-->mu+mu-) < 6.0E-9 at 95% confidence level. We observe an excess of B_s candidates. The probability that the background processes alone could produce such an excess or larger is 0.27%. The probability that the combination of background and the expected standard model rate of B_s --> mu+mu- could produce such an excess or larger is 1.9%. These data are used to determine BF(B_s-->mu+mu-) = (1.8^{+1.1}_{-0.9})E-8 and provide an upper limit of BF(B_s -->mu+mu-) < 4.0E-8 at 95% confidence level.Comment: 7 pages, 1 figure; version accepted by PR

    Search for light bosons in decays of the 125 GeV Higgs boson in proton-proton collisions at root s=8 TeV

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    Measurement of the top quark mass using single top quark events in proton-proton collisions at root s=8 TeV

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