Some tests associated with the exponential distribution

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Sexual risk behaviour among school-going adolescents in Sierra Leone and Liberia: a secondary analysis of the 2017 Global school-based student health surveys

From Springer Nature via Jisc Publications RouterHistory: received 2022-08-08, accepted 2022-10-18, registration 2022-10-19, collection 2022-12, pub-electronic 2022-12-24, online 2022-12-24Acknowledgements: Acknowledgements: We want to thank the high school students who participated in the 2017 Sierra Leone and Liberian GSHS. This paper uses data from the Global School-based Student Health Survey. GSHS is supported by the World Health Organization and the US Centre for Disease Control and Prevention.Publication status: PublishedAbdulai Jawo Bah - ORCID: 0000-0002-3334-7882 https://orcid.org/0000-0002-3334-7882Background: Sierra Leone and Liberia have experienced civil wars and, recently, Ebola outbreaks that led to profound economic hardship, psychopathologies and family disruptions. These factors are associated with sexual risk behaviours among youths. However, there is very little information on sexual risk behaviour among Sierra Leonean and Liberian school-going adolescents. The present study assessed the prevalence and determinants of sexual risk behaviours among school-going adolescents (10–19 years) in Sierra Leone and Liberia. Method: We used publicly available nationally representative cross-sectional datasets of the 2017 Sierra Leone and Liberia Global school health survey. The sample consisted of 2798 and 2744 school-going adolescents from Sierra Leone and Liberia, respectively. Complex sample descriptive and regression analysis was used to analyse our data. Results: The majority of adolescents in the two countries were involved in multiple sexual risk behaviour (80.2%), with a higher prevalence observed in Sierra Leone (85.2%) than in Liberia (75.3%). Liberian adolescents showed lesser odds of indulging in multiple sexual risk behaviours than their Sierra Leonean counterparts (AOR = 0.572; 95%CI: 0.345–0.946). Male, compared to females, were more likely to engage in multiple sexual risk behaviour (AOR = 2.310;95%CI:1.543–3.458), with a similar pattern observed in both countries. Alcohol use was associated with multiple sexual risk behaviour (AOR = 3.064; 95%CI: 2.137–4.392). Also, in Sierra Leone and Liberia, adolescents with one and two or more forms of psychological distress were more likely to have ever had sex than those who did not show any form of psychological distress. Missing class/school was associated with multiple sexual risk behaviour (AOR = 1.655; 95%CI:1.133–2.418). Peer support was only found to be a protective factor against no condom use among Liberian adolescents (AOR = 0.608; 95%CI: 0.435–0.850). Less parental support was only associated with ever had sex among adolescents in Sierra Leone (AOR = 2.027; 95%CI: 1.322–3.107) but not in Liberia (AOR = 1.034; 95%CI: 0.650–1.644). Conclusion: Our study found a high sexual risk behaviour among school-going adolescents in Sierra Leone and Liberia. Our finding highlights the need to strengthen sexual and reproductive health education in schools and communities that incorporate mental health promotion activities tailored to this group.pubpu

The use of condoms and other birth control methods among sexually active school-going adolescents in nine sub-Saharan African countries

From Springer Nature via Jisc Publications RouterHistory: received 2022-07-29, collection 2022-12, registration 2022-12-12, accepted 2022-12-12, pub-electronic 2022-12-16, online 2022-12-16Acknowledgements: Acknowledgements: We want to thank the high school students who participated in the GSHS nine countries. This paper uses data from the Global School Health survey. GSHS is supported by the World Health Organization and the US Centre for Disease Control and Prevention.Publication status: PublishedAbdulai Jawo Bah - ORCID: 0000-0002-3334-7882 https://orcid.org/0000-0002-3334-7882Background: Adolescents in sub-Saharan Africa still face sexual and reproductive health challenges. Contraceptives have been used to address these challenges. Despite efforts at national and global levels, contraceptive uptake among young people in Africa remains a challenge due to personal, societal, and health systems-based barriers. We estimated the prevalence and correlates of condom use and other birth control methods among sexually active school-going adolescents in nine sub-Saharan African (SSA) countries. Methods: We conducted a secondary analysis of the Global School-based Student Health Surveys (GSHS) datasets pooled from nine SSA countries. We included a sample of 27,504 school-going adolescents 11 years and younger and 18 years and older. We employed meta-analysis using a random-effects model to estimate the total prevalence of the use of condoms, other birth control methods other than a condom and any birth control method at last sexual intercourse. We conducted complex sample descriptive and logistic regression analyses to determine the characteristics and determinants of not using condoms and other birth control methods among sexually active school-going adolescents in nine sub-Saharan African countries, respectively. Results: More than half [n = 4430, 53.8% (43.9–63.8)], two-fifth [n = 3242, 39.5% (33.2–45.9) and two-thirds of adolescents [n = 4838, 65.6% (57.5–73.7)] of sexually active in school adolescents across the nine sub-Saharan African countries used condom, other birth control methods and any form birth control method during their last sexual intercourse, respectively. The non-use of condoms at last sex was associated with being younger (less than 16 years) [AOR = 1.48;95%CI: 1.12–1.94], early sexual debut [AOR = 1.81(1.47–2.22)], having two or more sexual partners [AOR = 1.30(1.06–1.58)] and no/minimal parental support [AOR = 1.54(1.17–2.03)]. The non-use of other birth control methods at last sex was associated with being male [AOR = 1.37 (1.09–1.73)], early sexual debut [AOR = 1.83(1.48–2.27) and having no parental support [AOR = 1.64(1.34–2.00)]. Conclusion: Contraceptive need among sexually active school adolescents in the nine sub-Saharan African countries is high. Such a need calls for the development of country-specific and or the review of existing school-based sexual health education and youth-friendly sexual and reproductive health interventions that target risky adolescents and promote adolescent-parent effective communication, connectedness and support.pubpu

Student Satisfaction with Hostel facilities: A Case Study of Njala University, Njala Campus, Sierra Leone

Aim and Scope: The importance of students' social environments in their day-to-day lives cannot be overstated. The extent to which students are happy in their hostel depends on its facilities' availability, adequacy, and functionality. A case study of Njala University, Njala campus, was used to determine the amenities provided and the level of satisfaction the students derived from those amenities. Methods: A cross-sectional research design was used to conduct the research through in-field observations and a standardized questionnaire. The study's sample size was estimated at 482 total students. SPSS version 26.0 was used for the data analysis. Result: The study revealed that 82.0% of the respondents were within the age group 20-29 years, and more than two-thirds (70.7%) of the respondents were living in overcrowded rooms with a population of more than the required number of persons per room; this is attributed to the squatting phenomenon among the hostel occupants with the attendant implications of increasing pressure on the available facilities. Equally, students were reasonably satisfied with hostel facilities such as recreational grounds, security status, Library/ICT, waste management and electricity. Results showed respondents were unhappy with the adequacy and performance of certain facilities such as the drainage system, foam, toilet, water supply, kitchen, room size, laundry, and firefighting device. Conclusion: For student convenience, as enrollment continues to rise, the paper suggests that public-private partnerships be established to fund the construction of other hostels with updated designs and amenities

Student Satisfaction with Hostel Facilities: A Case Study of Njala University, Njala Campus, Sierra Leone

Aim and Scope: The importance of students' social environments intheir day-to-day lives cannot be overstated. The extent to which students arehappy in their hostel depends on its facilities' availability, adequacy, andfunctionality. A case study of Njala University, Njala campus, was used todetermine the amenities provided and the level of satisfaction the students derived from those amenities. Methods: A cross-sectional research designwas used to conduct the research through a close-ended questionnaire. Thestudy's sample size was 482 students. SPSS version 26.0 was used for the dataanalysis. Result: Most (82.0%) of the respondents were within the age group20-29 years, and more than two-thirds (70.7%) were living in overcrowdedrooms with double the number than the room was designed for.; this isattributed to the common phenomenon of students who get a place sub-lettingto their less fortunate colleagues on a cost-sharing basis. Overcrowding hasimplications of increasing pressure on the available facilities. Students werereasonably satisfied with hostel facilities such as recreational grounds, securitystatus, Library/ICT, waste management, and electricity, but very dissatisfiedwith the drainage system, state of mattresses, toilet facilities, water supply,kitchen, room size, laundry, and lack of firefighting devices. Conclusion :Students are dissatisfied with current facilities as enrollment continues to risefaster than Government intervention the paper suggests that a public-privatepartnership be established to fund the construction of other hostels withupdated designs and amenities

Student Satisfaction with Hostel facilities: A Case Study of Njala University, Njala Campus, Sierra Leone

Aim and Scope: The importance of students' social environments in their day-to-day lives cannot be overstated. The extent to which students are happy in their hostel depends on its facilities' availability, adequacy, and functionality. A case study of Njala University, Njala campus, was used to determine the amenities provided and the level of satisfaction the students derived from those amenities. Methods: A cross-sectional research design was used to conduct the research through in-field observations and a standardized questionnaire. The study's sample size was estimated at 482 total students. SPSS version 26.0 was used for the data analysis. Result: The study revealed that 82.0% of the respondents were within the age group 20-29 years, and more than two-thirds (70.7%) of the respondents were living in overcrowded rooms with a population of more than the required number of persons per room; this is attributed to the squatting phenomenon among the hostel occupants with the attendant implications of increasing pressure on the available facilities. Equally, students were reasonably satisfied with hostel facilities such as recreational grounds, security status, Library/ICT, waste management and electricity. Results showed respondents were unhappy with the adequacy and performance of certain facilities such as the drainage system, foam, toilet, water supply, kitchen, room size, laundry, and firefighting device. Conclusion: For student convenience, as enrollment continues to rise, the paper suggests that public-private partnerships be established to fund the construction of other hostels with updated designs and amenities

Do disempowered childbearing women give birth at home in Sierra Leone? A secondary analysis of the 2019 Sierra Leone demographic health survey

From Springer Nature via Jisc Publications RouterHistory: received 2022-09-02, registration 2023-11-14, accepted 2023-11-14, epub 2023-11-22, online 2023-11-22, collection 2023-12Acknowledgements: We want to thank the MEASURE DHS for granting us access to use the 2019 SLDHS data.Publication status: PublishedAbdulai Jawo Bah - ORCID: 0000-0002-3334-7882 https://orcid.org/0000-0002-3334-7882Background: A nationwide assessment of the link between women’s empowerment and homebirth has not been fully examined in Sierra Leone. Our study examined the association between women’s empowerment and homebirth among childbearing women in Sierra Leone using the 2019 Sierra Leone Demographic Health Survey (2019 SLDHS) data. Method: We used the individual file (IR) of the 2019 SLDHS dataset for our analysis. A total of 7377 women aged 15–49 years who gave birth in the five years preceding the survey were included. Outcome variable was “home birth of their last child among women in the five years preceding the 2019 SLDHS. Women’s empowerment parameters include women’s knowledge level, economic participation, decision-making ability and power to refuse the idea of intimate partner violence. We used the complex sample command on SPSS version 28 to conduct descriptive and multivariate logistic regression analyses. Results: Three in every 20 women had home childbirth (n = 1177; 15.3%). Women with low [aOR 2.04; 95% CI 1.43–2.92] and medium [aOR 1.44; 95%CI 1.05–1.97] levels of knowledge had higher odds of giving birth at home compared to those with high levels of knowledge. Women who did not have power to refuse the idea of intimate partner violence against women were more likely to had given birth at home [aOR 1.38; 95% CI1.09-1.74]. In addition, women with no [aOR 2.71; 95% CI1.34-5.46) and less than four antenatal care visits [aOR 2.08; 95% CI:1.51–2.88] and for whom distance to a health facility was a major problem [aOR 1.95; 95% CI1.49-2.56] were more likely to have had a homebirth. However, no statistically significant association was observed between a women’s decision-making power and home birth [aOR 1.11; 95% CI 0.86–1.41]. Conclusion: Despite improvements in maternal health indicators, homebirth by unskilled birth attendants is still a public health concern in Sierra Leone. Women with low knowledge levels, who did not have power to refuse the idea of intimate partner violence against women, had less than four ANC visits and considered distance to a health facility as a major problem had higher odds of giving birth at home. Our findings reflect the need to empower women by improving their knowledge level through girl child and adult education, increasing media exposure, changing societal norms and unequal power relations that promote gender-based violence against women, and improving roads and transport infrastructure.pubpu

Isolation of Angola-like Marburg virus from Egyptian rousette bats from West Africa.

Marburg virus (MARV) causes sporadic outbreaks of severe Marburg virus disease (MVD). Most MVD outbreaks originated in East Africa and field studies in East Africa, South Africa, Zambia, and Gabon identified the Egyptian rousette bat (ERB; Rousettus aegyptiacus) as a natural reservoir. However, the largest recorded MVD outbreak with the highest case-fatality ratio happened in 2005 in Angola, where direct spillover from bats was not  shown. Here, collaborative studies by the Centers for Disease Control and Prevention, Njala University, University of California, Davis USAID-PREDICT, and the University of Makeni identify MARV circulating in ERBs in Sierra Leone. PCR, antibody and virus isolation data from 1755 bats of 42 species shows active MARV infection in approximately 2.5% of ERBs. Phylogenetic analysis identifies MARVs that are similar to the Angola strain. These results provide evidence of MARV circulation in West Africa and demonstrate the value of pathogen surveillance to identify previously undetected threats

Folding and trimerization of signal sequence-less mature TolC in the cytoplasm of Escherichia coli

TolC is a multifunctional outer-membrane protein (OMP) of Escherichia coli that folds into a unique α/β-barrel structure. Previous studies have shown that unlike the biogenesis of β-barrel OMPs, such as porins, TolC assembles independently from known periplasmic folding factors. Yet, the assembly of TolC, like that of β-barrel OMPs, is dependent on BamA and BamD, two essential components of the β-barrel OMP assembly machinery. We have investigated the folding properties and cellular trafficking of a TolC derivative that lacks the entire signal sequence (TolCΔ2–22). A significant amount of TolCΔ2–22 was found to be soluble in the cytoplasm, and a fraction of it folded and trimerized into a conformation similar to that of the normal outer membrane-localized TolC protein. Some TolCΔ2–22 was found to associate with membranes, but failed to assume a wild-type-like folded conformation. The null phenotype of TolCΔ2–22 was exploited to isolate suppressor mutations, the majority of which mapped in secY. In the secY suppressor background, TolCΔ2–22 resumed normal function and folded like wild-type TolC. Proper membrane insertion could not be achieved upon in vitro incubation of cytoplasmically folded TolCΔ2–22 with purified outer membrane vesicles, showing that even though TolC is intrinsically capable of folding and trimerization, for successful integration into the outer membrane these events need to be tightly coupled to the insertion process, which is mediated by the Bam machinery. Genetic and biochemical data attribute the unique folding and assembly pathways of TolC to its large soluble α-helical domain