156 research outputs found
Matrix Development in Self-Assembly of Articular Cartilage
- Author
- A Asanbaeva
- A Asanbaeva
- A Calabro
- AF Sherwin
- AG Bharadwaj
- AJ Hayes
- AK Williamson
- AK Williamson
- AN Brown
- AO Oshin
- BD Elder
- BD Elder
- CA Poole
- CA Poole
- CA Poole
- Christopher M. Revell
- CW Archer
- D Platt
- David D. Allison
- E Ruoslahti
- EH Morrison
- EJ Koay
- F Guilak
- F Guilak
- FM Craig
- GE Kempson
- GE Kempson
- Gidon Ofek
- I Youn
- IM Shapiro
- JC Hu
- JC Hu
- JC Hu
- JC Shelton
- Jerry C. Hu
- JF Woessner Jr
- JM Sorrell
- K Hashimoto
- K Pietila
- K. Jane Grande-Allen
- KA Athanasiou
- KA Athanasiou
- KJ Grande-Allen
- KJ Grande-Allen
- KM Daumer
- Kyriacos A. Athanasiou
- L Rosenberg
- LG Alexopoulos
- LG Alexopoulos
- LG Alexopoulos
- M Pacifici
- MA Dimicco
- MA Haider
- MM Knight
- MT Bayliss
- O Pullig
- P Pavasant
- R Quarto
- RA Foty
- S Lewis
- SA Fraser
- SA Oberlender
- SA Oberlender
- Sotirios Koutsopoulos
- VC Mow
- VC Mow
- VC Mow
- WA Hing
- Y Kawakami
- YS Bland
- Publication venue
- Public Library of Science
- Publication date
- 01/07/2008
- Field of study
Articular cartilage is a highly functional tissue which covers the ends of long bones and serves to ensure proper joint movement. A tissue engineering approach that recapitulates the developmental characteristics of articular cartilage can be used to examine the maturation and degeneration of cartilage and produce fully functional neotissue replacements for diseased tissue.This study examined the development of articular cartilage neotissue within a self-assembling process in two phases. In the first phase, articular cartilage constructs were examined at 1, 4, 7, 10, 14, 28, 42, and 56 days immunohistochemically, histologically, and through biochemical analysis for total collagen and glycosaminoglycan (GAG) content. Based on statistical changes in GAG and collagen levels, four time points from the first phase (7, 14, 28, and 56 days) were chosen to carry into the second phase, where the constructs were studied in terms of their mechanical characteristics, relative amounts of collagen types II and VI, and specific GAG types (chondroitin 4-sulfate, chondroitin 6-sulfate, dermatan sulfate, and hyaluronan). Collagen type VI was present in initial abundance and then localized to a pericellular distribution at 4 wks. N-cadherin activity also spiked at early stages of neotissue development, suggesting that self-assembly is mediated through a minimization of free energy. The percentage of collagen type II to total collagen significantly increased over time, while the proportion of collagen type VI to total collagen decreased between 1 and 2 wks. The chondroitin 6- to 4- sulfate ratio decreased steadily during construct maturation. In addition, the compressive properties reached a plateau and tensile characteristics peaked at 4 wks.The indices of cartilage formation examined in this study suggest that tissue maturation in self-assembled articular cartilage mirrors known developmental processes for native tissue. In terms of tissue engineering, it is suggested that exogenous stimulation may be necessary after 4 wks to further augment the functionality of developing constructs
Educational attainment among survivors of childhood cancer: a population-based cohort study in Denmark
- Author
- A Charlton
- A M T Kejs
- A Maggiolini
- AE Schlieper
- AF Mancini
- AW Glaser
- B Lannering
- BP de Nully
- C Eiser
- C Johansen
- F Berrino
- G Engholm
- G Pastore
- HH Storm
- J Kelaghan
- J Lynch
- JE Dongen-Melman
- JM Birch
- K Schmiegelow
- L Adamoli
- L Thygesen
- M Jankovic
- MJ Teta
- N Breslow
- NE Langeveld
- PA Mitby
- PD Allison
- R Haupt
- S V Koch
- T Langer
- TP Jensen
- TS Reimers
- VC Peckham
- WA Bleyer
- Publication venue
- Nature Publishing Group
- Publication date
- Field of study
Pharmacokinetic role of protein binding of mycophenolic acid and its glucuronide metabolite in renal transplant recipients
- Author
- AC Allison
- AG Johnson
- B Kaplan
- BA Atcheson
- BA Atcheson
- BA Kiberd
- BC Winter de
- BC Winter de
- Brenda C. M. de Winter
- D Cockroft
- DA Hesselink
- DR Kuypers
- EN Jonsson
- F Sombogaard
- Ferdi Sombogaard
- FM Gonzalez-Roncero
- G Filler
- G Knoll
- I Nowak
- I Tsina
- JP Tillement
- K Bowalgaha
- Leslie M. Shaw
- LM Shaw
- LM Shaw
- LM Shaw
- LT Weber
- LT Weber
- LZ Benet
- M Danhof
- M Naesens
- MD Hale
- P Glander
- PR Jadhav
- RE Bullingham
- Reinier M. van Hest
- RM Hest van
- RM Hest van
- RM Hest van
- Ron A. A. Mathot
- T Gelder van
- T Gelder van
- T Gelder van
- T Gelder van
- Teun van Gelder
- VC Cox
- Y Le Meur
- Z Jiao
- Publication venue
- Springer US
- Publication date
- 01/01/2009
- Field of study
Mycophenolic acid (MPA), the active compound of mycophenolate mofetil (MMF), is used to prevent graft rejection in renal transplant recipients. MPA is glucuronidated to the metabolite MPAG, which exhibits enterohepatic recirculation (EHC). MPA binds for 97% and MPAG binds for 82% to plasma proteins. Low plasma albumin concentrations, impaired renal function and coadministration of cyclosporine have been reported to be associated with increased clearance of MPA. The aim of the study was to develop a population pharmacokinetic model describing the relationship between MMF dose and total MPA (tMPA), unbound MPA (fMPA), total MPAG (tMPAG) and unbound MPAG (fMPAG). In this model the correlation between pharmacokinetic parameters and renal function, plasma albumin concentrations and cotreatment with cyclosporine was quantified. tMPA, fMPA, tMPAG and fMPAG concentration–time profiles of renal transplant recipients cotreated with cyclosporine (n = 48) and tacrolimus (n = 45) were analyzed using NONMEM. A 2- and 1-compartment model were used to describe the pharmacokinetics of fMPA and fMPAG. The central compartments of fMPA and fMPAG were connected with an albumin compartment allowing competitive binding (bMPA and bMPAG). tMPA and tMPAG were modeled as the sum of the bound and unbound concentrations. EHC was modeled by transport of fMPAG to a separate gallbladder compartment. This transport was decreased in case of cyclosporine cotreatment (P < 0.001). In the model, clearance of fMPAG decreased when creatinine clearance (CrCL) was reduced (P < 0.001), and albumin concentration was correlated with the maximum number of binding sites available for MPA and MPAG (P < 0.001). In patients with impaired renal function cotreated with cyclosporine the model adequately described that increasing fMPAG concentrations decreased tMPA AUC due to displacement of MPA from its binding sites. The accumulated MPAG could also be reconverted to MPA by the EHC, which caused increased tMPA AUC in patients cotreated with tacrolimus. Changes in CrCL had hardly any effect on fMPA exposure. A decrease in plasma albumin concentration from 0.6 to 0.4 mmol/l resulted in ca. 38% reduction of tMPA AUC, whereas no reduction in fMPA AUC was seen. In conclusion, a pharmacokinetic model has been developed which describes the relationship between dose and both total and free MPA exposure. The model adequately describes the influence of renal function, plasma albumin and cyclosporine co-medication on MPA exposure. Changes in protein binding due to altered renal function or plasma albumin concentrations influence tMPA exposure, whereas fMPA exposure is hardly affected
Identification of bacterial glycosidases in rat cecal contents
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/09/1981
- Field of study
Cecal contents of conventional and germfree rats were examined for glycosidases which may have a role in degrading glycoprotein oligosaccharides. Utilizing p-nitrophenylglycosides as substrates, we identified glycosidases in bacteria-free supernatants from cecal contents which act on β-linkages. These cecal glycosidases appear to be of bacterial origin since: (1) direct comparisons of the enzymes in similar contents from germfree rats showed negligible activities; (2) most of the glycosidase levels in bacterial extracts were at least as high as those of soluble supernatants; and (3) disk gel electrophoresis of contents and bacterial extracts revealed in both preparations a β- N -acetylglucosaminidase band with similar R f s. Also, the blood group B antigenicity of germfree cecal glycoproteins was greatly decreased by conventional cecal contents. These findings indicate that β-galactosidase and β- N -acetylgalactosaminidase in cecal contents are bacterial in origin, and they may have a role in the bacterial catabolism of intestinal glycoproteins.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/44391/1/10620_2005_Article_BF01309607.pd
The Molecular Epidemiology and Evolution of Murray Valley Encephalitis Virus: Recent Emergence of Distinct Sub-lineages of the Dominant Genotype 1
- Author
- A Brown
- A Niazi
- AJ Drummond
- AJ Drummond
- AJ Schuh
- AJ Schuh
- Alyssa Pyke
- AN Gordon
- AT Pyke
- Aziz-ur-Rahman Niazi
- B Murrell
- B Murrell
- B Shrestha
- BD Lindenbach
- Belinda Herring
- Beng Hooi Chua
- C Johansen
- C Taucher
- CA Johansen
- CH Woelk
- Cheryl A. Johansen
- CK Chuang
- CT Davis
- CW Lin
- D Darriba
- David T. Williams
- David W.C. Beasley
- DT Williams
- DT Williams
- DW Beasley
- DW Beasley
- DW Beasley
- E Lee
- EF Pettersen
- EL French
- EL French
- FA Rey
- FJ May
- FX Heinz
- G Jerzak
- GE Nybakken
- GJ Baillie
- GJ Fitzsimmons
- GM Jenkins
- ID Marshall
- J Aaskov
- J Burrow
- J Mackenzie
- JA Forbes
- JD Brien
- JG Peng
- John S. Mackenzie
- JS Mackenzie
- JS Mackenzie
- JS Mackenzie
- JS Mackenzie
- K Arnold
- K Morita
- K Tamura
- K Yoshii
- L Heath
- LA Selvey
- LD Kramer
- M Lobigs
- M Lobigs
- M Poidinger
- M Worobey
- MA Lawson
- MA Mohammed
- NA Prow
- PC McMinn
- PC McMinn
- Peter A. Durr
- Pond SL Kosakovsky
- Pond SL Kosakovsky
- PT Nga
- R Fritz
- RA Mann
- RC Gualano
- RJ Coelen
- RJ Coelen
- RJ Hurrelbrink
- RJ Hurrelbrink
- RM Moudy
- S Craig
- S Doggett
- S Elshuber
- S Guindon
- SE Roche
- SG Anderson
- Sinéad M. Diviney
- SL Allison
- SL Doggett
- SL Pond
- SP Ma
- SS Twiddy
- Stephen L. Doggett
- SY Shiu
- T Oliphant
- T Oliphant
- TM Colpitts
- TT Tan
- V Pierre
- VC Luca
- WD Crill
- WR Chen
- XL Pan
- Y Modis
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 01/01/2015
- Field of study
© 2015 Williams et al. Background: Recent increased activity of the mosquito-borne Murray Valley encephalitis virus (MVEV) in Australia has renewed concerns regarding its potential to spread and cause disease. Methodology/Principal Findings: To better understand the genetic relationships between earlier and more recent circulating strains, patterns of virus movement, as well as the molecular basis of MVEV evolution, complete pre-membrane (prM) and Envelope (Env) genes were sequenced from sixty-six MVEV strains from different regions of the Australasian region, isolated over a sixty year period (1951–2011). Phylogenetic analyses indicated that, of the four recognized genotypes, only G1 and G2 are contemporary. G1 viruses were dominant over the sampling period and found across the known geographic range of MVEV. Two distinct sub-lineages of G1 were observed (1A and 1B). Although G1B strains have been isolated from across mainland Australia, Australian G1A strains have not been detected outside northwest Australia. Similarly, G2 is comprised of only Western Australian isolates from mosquitoes, suggesting G1B and G2 viruses have geographic or ecological restrictions. No evidence of recombination was found and a single amino acid substitution in the Env protein (S332G) was found to be under positive selection, while several others were found to be under directional evolution. Evolutionary analyses indicated that extant genotypes of MVEV began to diverge from a common ancestor approximately 200 years ago. G2 was the first genotype to diverge, followed by G3 and G4, and finally G1, from which subtypes G1A and G1B diverged between 1964 and 1994. Conclusions/Significance: The results of this study provides new insights into the genetic diversity and evolution of MVEV. The demonstration of co-circulation of all contemporary genetic lineages of MVEV in northwestern Australia, supports the contention that this region is the enzootic focus for this virus
Measurement of Higgs boson production in the diphoton decay channel in pp collisions at center-of-mass energies of 7 and 8 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdinov O
- Aben R
- Abi B
- Abolins M
- AbouZeid OS
- Abramowicz H
- Abreu H
- Abreu R
- Abulaiti Y
- Acharya BS
- Adam ER
- Adamczyk L
- Adams DL
- Adelman J
- Adomeit S
- Adye T
- Agatonovic-Jovina T
- Aguilar-Saavedra JA
- Agustoni M
- Ahlen SP
- Ahmadov F
- Aielli G
- Akerstedt H
- Akesson TP
- Akimoto G
- Akimov AV
- Alberghi GL
- Albert J
- Albrand S
- Alconada Verzini MJ
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Alimonti G
- Alio L
- Alison J
- Allbrooke BMM
- Allison LJ
- Allport PP
- Aloisio A
- Alonso A
- Alonso F
- Alpigiani C
- Altheimer A
- Alviggi MG
- Amako K
- Amaral Coutinho Y
- Amelung C
- Amidei D
- Amor Dos Santos SP
- Amorim A
- Amoroso S
- Amram N
- Amundsen G
- Anastopoulos C
- Ancu LS
- Andari N
- Andeen T
- Anders CF
- Anders G
- Anderson KJ
- Andreazza A
- Andrei V
- Anduaga XS
- Angelidakis S
- Angelozzi I
- Anger P
- Angerami A
- Anghinolfi F
- Anh TV
- Anisenkov AV
- Anjos N
- Annovi A
- Antonaki A
- Antonelli M
- Antonov A
- Antos J
- Anulli F
- Aoki M
- Apolle R
- Arabidze G
- Aracena I
- Arai Y
- Aranda CP
- Araque JP
- Arce ATH
- Arguin J-F
- Argyropoulos S
- Arik M
- Armadans RC
- Armbruster AJ
- Arnaez O
- Arnal V
- Arnold H
- Arratia M
- Arslan O
- Artamonov A
- Artoni G
- Asai S
- Asbah N
- Ashkenazi A
- Asman B
- Asquith L
- Assamagan K
- Astalos R
- Atkinson M
- Atlay NB
- Auerbach B
- Augsten K
- Aurousseau M
- Avolio G
- Azuelos G
- Azuma Y
- Baak MA
- Baas AE
- Bacci C
- Bachacou H
- Bachas K
- Backes M
- Backhaus M
- Badescu E
- Bagiacchi P
- Bagnaia P
- Bai Y
- Bain T
- Baines JT
- Baker OK
- Balek P
- Balli F
- Banas E
- Banerjee S
- Bannoura AAE
- Bansal V
- Bansil HS
- Barajas CAC
- Barak L
- Baranov P
- Barberio EL
- Barberis D
- Barbero M
- Barillari T
- Barisonzi M
- Barklow T
- Barlow N
- Barnett BM
- Barnett RM
- Barnovska Z
- Baroncelli A
- Barone G
- Barr AJ
- Barreiro F
- Barrera CO
- Bartoldus R
- Barton AE
- Bartos P
- Bartsch V
- Bassalat A
- Basye A
- Bates RL
- Batley JR
- Battaglia M
- Battistin M
- Bauer F
- Bawa HS
- Beattie MD
- Beau T
- Beauchemin PH
- Beccherle R
- Bechtle P
- Beck HP
- Becker K
- Becker S
- Beckingham M
- Becot C
- Beddall A
- Beddall AJ
- Bedikian S
- Bednyakov VA
- Bee CP
- Beemster LJ
- Beermann TA
- Begel M
- Behr K
- Belanger-Champagne C
- Belenguer MJ
- Bell PJ
- Bell WH
- Bella G
- Bella LA
- Bellagamba L
- Bellerive A
- Bellomo M
- Belotskiy K
- Beltramello O
- Benary O
- Benchekroun D
- Bendtz K
- Benekos N
- Benhammou Y
- Benjamin DP
- Bensinger JR
- Benslama K
- Bentvelsen S
- Berge D
- Berger N
- Berghaus F
- Beringer J
- Berlingen JM
- Bernard C
- Bernat P
- Bernius C
- Bernlochner FU
- Berry T
- Berta P
- Bertella C
- Bertoli G
- Bertolucci F
- Bertsche C
- Bertsche D
- Besana MI
- Besjes GJ
- Bessidskaia O
- Bessner M
- Besson N
- Betancourt C
- Bethke S
- Bhimji W
- Bianchi RM
- Bianchini L
- Bianco M
- Biebel O
- Bieniek SP
- Bierwagen K
- Biesiada J
- Biglietti M
- Bilokon H
- Bindi M
- Binet S
- Bingul A
- Bini C
- Black CW
- Black JE
- Black KM
- Blackburn D
- Blair RE
- Blanchard J-B
- Blazek T
- Bloch I
- Blocker C
- Blum W
- Blumenschein U
- Bobbink GJ
- Bobrovnikov VS
- Bocchetta SS
- Bocci A
- Bock C
- Boddy CR
- Boehler M
- Boek TT
- Boeriu OEV
- Bogaerts JA
- Bogdanchikov AG
- Bogouch A
- Bohm C
- Bohm J
- Boisvert V
- Bold T
- Boldea V
- Boldyrev AS
- Bomben M
- Bona M
- Boonekamp M
- Borisov A
- Borissov G
- Borri M
- Borroni S
- Bortfeldt J
- Bortolotto V
- Bos K
- Boscherini D
- Bosman M
- Boterenbrood H
- Boudreau J
- Bouffard J
- Bouhova-Thacker EV
- Boumediene D
- Bourdarios C
- Bousson N
- Boutouil S
- Boveia A
- Boyd J
- Boyko R
- Bozic I
- Bracinik J
- Brandt A
- Brandt G
- Brandt O
- Bratzler U
- Brau B
- Brau JE
- Braun HM
- Brazzale SF
- Brelier B
- Brendlinger K
- Brennan AJ
- Brenner R
- Bressler S
- Bret MC
- Bristow K
- Bristow TM
- Britton D
- Brochu FM
- Brock I
- Brock R
- Bromberg C
- Bronner J
- Brooijmans G
- Brooks T
- Brooks WK
- Brosamer J
- Brost E
- Brown J
- Bruncko D
- Bruneliere R
- Brunet S
- Bruni A
- Bruni G
- Bruschi M
- Bryngemark L
- Buanes T
- Buat Q
- Bucci F
- Buchholz P
- Buckingham RM
- Buckley AG
- Buda SI
- Budagov IA
- Buehrer F
- Buescher D
- Buescher V
- Bueso XP
- Bugge L
- Bugge MK
- Bulekov O
- Bundock AC
- Burckhart H
- Burdin S
- Burghgrave B
- Burke S
- Burmeister I
- Busato E
- Bussey P
- Bustos ACF
- Buszello CP
- Butler B
- Butler JM
- Butt AI
- Buttar CM
- Butterworth JM
- Butti P
- Buttinger W
- Buzatu A
- Byszewski M
- Caforio D
- Cakir IT
- Cakir O
- Calafiura P
- Calandri A
- Calderini G
- Calfayan P
- Calkins R
- Caloba LP
- Calvet D
- Calvet S
- Camarda S
- Cameron D
- Caminada LM
- Campana S
- Campanelli M
- Campoverde A
- Canale V
- Canepa A
- Cantero J
- Cantrill R
- Cao T
- Caprini I
- Caprini M
- Capua M
- Caputo R
- Cardarelli R
- Carli T
- Carlino G
- Carminati L
- Caron S
- Carquin E
- Carrillo-Montoya GD
- Carter JR
- Carvalho J
- Casadei D
- Casado MP
- Casolino M
- Castaneda-Miranda E
- Castanheira MTD
- Castelli A
- Castillo IS
- Castillo LRF
- Castro NF
- Catastini P
- Catinaccio A
- Catmore JR
- Cattai A
- Cattani G
- Caudron J
- Cavaliere V
- Cavalli D
- Cavalli-Sforza M
- Cavasinni V
- Ceradini F
- Cerio BC
- Cerny K
- Cerqueira AS
- Cerri A
- Cerrito L
- Cerutti F
- Cerv M
- Cervelli A
- Cetin SA
- Chafaq A
- Chakraborty D
- Chalupkova I
- Chang P
- Chapleau B
- Chapman JD
- Charfeddine D
- Charlton DG
- Chau CC
- Cheatham S
- Chegwidden A
- Chekanov S
- Chekulaev SV
- Chelkov GA
- Chelstowska MA
- Chen C
- Chen H
- Chen K
- Chen L
- Chen S
- Chen X
- Chen Y
- Chen Y
- Cheng HC
- Cheng Y
- Cheplakov A
- Chernyatin V
- Cheu E
- Chevalier L
- Chiarella V
- Chiefari G
- Childers JT
- Chilingarov A
- Chiodini G
- Chisholm AS
- Chislett RT
- Chitan A
- Chizhov MV
- Chouridou S
- Chow BKB
- Chromek-Burckhart D
- Chu ML
- Chudoba J
- Chwastowski JJ
- Chytka L
- Ciapetti G
- Ciftci AK
- Ciftci R
- Cinca D
- Cindro V
- Ciocio A
- Cirkovic P
- Citron ZH
- Citterio M
- Ciubancan M
- Clark A
- Clark PJ
- Clarke RN
- Cleland W
- Clemens JC
- Clement C
- Coadou Y
- Cobal M
- Coccaro A
- Cochran J
- Codina EP
- Coffey L
- Cogan JG
- Coggeshall J
- Cole B
- Cole S
- Colijn AP
- Collaboration ATLAS
- Collot J
- Colombo T
- Colon G
- Compostella G
- Coniavitis E
- Conidi MC
- Connell SH
- Connelly IA
- Consonni SM
- Consorti V
- Constantinescu S
- Conta C
- Conti G
- Conventi F
- Cooke M
- Cooper BD
- Cooper-Sarkar AM
- Cooper-Smith NJ
- Copic K
- Cornelissen T
- Corradi M
- Correia AMH
- Corriveau F
- Corso-Radu A
- Cortes-Gonzalez A
- Cortiana G
- Costa G
- Costa MJ
- Costanzo D
- Cote D
- Cottin G
- Cowan G
- Cox BE
- Cranmer K
- Cree G
- Crepe-Renaudin S
- Crescioli F
- Cribbs WA
- Cristinziani M
- Croft V
- Crosetti G
- Cuciuc C-M
- Cummings J
- Curatolo M
- Cuthbert C
- Czirr H
- Czodrowski P
- Czyczula Z
- D'Auria S
- D'Onofrio M
- da Costa JBG
- Da Costa JGPF
- Da Via C
- Dabrowski W
- Dafinca A
- Dai T
- Dale O
- Dallaire F
- Dallapiccola C
- Dam M
- Damazio DO
- Daniells AC
- Dao V
- Darbo G
- Darmora S
- Dassoulas JA
- Dattagupta A
- Davey W
- David C
- Davidek T
- Davies E
- Davies M
- Davignon O
- Davison AR
- Davison P
- Davygora Y
- Dawe E
- Dawson I
- Daya-Ishmukhametova RK
- de Andrade Filho LM
- de Asmundis R
- De Bruin PHS
- De Castro S
- De Cecco S
- De Groot N
- De Jong P
- De la Hoz SG
- De la Torre H
- de Lima DEF
- De Lorenzi F
- De Mendizabal JB
- De Nooij L
- De Pedis D
- De Regie JBDV
- de Renstrom PAB
- De Salvo A
- De Sanctis U
- De Santo A
- De Sousa MJDCS
- De K
- Dearnaley WJ
- Debbe R
- Debenedetti C
- Dechenaux B
- Dedovich DV
- Deigaard I
- Del Peso J
- Del Prete T
- Delgado AT
- Deliot F
- Delitzsch CM
- Deliyergiyev M
- Dell'Acqua A
- Dell'Asta L
- Dell'Orso M
- Della Pietra M
- della Porta GZ
- Della Volpe D
- Delmastro M
- Delsart PA
- Deluca C
- Demers S
- Demichev M
- Demilly A
- Denisov SP
- Derendarz D
- Derkaoui JE
- Derue F
- Dervan P
- Desch K
- Deterre C
- Deviveiros PO
- Dewhurst A
- Dhaliwal S
- DHrssen M
- Di Ciaccio A
- Di Ciaccio L
- Di Domenico A
- Di Donato C
- Di Girolamo A
- Di Girolamo B
- Di Mattia A
- Di Micco B
- Di Nardo R
- Di Simone A
- Di Sipio R
- Di Valentino D
- Dias FA
- Diaz MA
- Diehl EB
- Dietrich J
- Dietzsch TA
- Diglio S
- Dimitrievska A
- Dingfelder J
- Dionisi C
- Dita P
- Dita S
- Dittus F
- Djama F
- Djobava T
- Djuvsland JI
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- Zhemchugov A
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- Zimmermann C
- Zimmermann R
- Zimmermann S
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- zur Nedden M
- Zurzolo G
- Zutshi V
- Zwalinski L
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2014
- Field of study
A measurement of the production processes of the recently discovered Higgs boson is performed in the two-photon final state using 4.5 fb[superscript −1] of proton-proton collisions data at √s=7 TeV and 20.3 fb[superscript −1] at √s=8 TeV collected by the ATLAS detector at the Large Hadron Collider. The number of observed Higgs boson decays to diphotons divided by the corresponding Standard Model prediction, called the signal strength, is found to be μ=1.17±0.27 at the value of the Higgs boson mass measured by ATLAS, m[subscript H]=125.4 GeV. The analysis is optimized to measure the signal strengths for individual Higgs boson production processes at this value of m[subscript H]. They are found to be μ[subscript ggF]=1.32±0.38, μ[subscript VBF]=0.8±0.7, μ[subscript WH]=1.0±1.6, μ[subscript ZH]=0.1[superscript +3.7 subscript −0.1], and μ[subscript t [bar over t] H] =1.6[superscript +2.7 subscript −1.8], for Higgs boson production through gluon fusion, vector-boson fusion, and in association with a W or Z boson or a top-quark pair, respectively. Compared with the previously published ATLAS analysis, the results reported here also benefit from a new energy calibration procedure for photons and the subsequent reduction of the systematic uncertainty on the diphoton mass resolution. No significant deviations from the predictions of the Standard Model are found.European Organization for Nuclear ResearchUnited States. Dept. of EnergyNational Science Foundation (U.S.)Brookhaven National Laborator
Search for the b(b)over-bar decay of the Standard Model Higgs boson in associated (W/Z)H production with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdinov O
- Aben R
- Abi B
- Abolins M
- AbouZeid OS
- Abramowicz H
- Abreu H
- Abreu R
- Abulaiti Y
- Acharya BS
- Adam ER
- Adamczyk L
- Adams DL
- Adelman J
- Adomeit S
- Adye T
- Agatonovic-Jovin T
- Aguilar-Saavedra JA
- Agustoni M
- Ahlen SP
- Ahmadov F
- Aielli G
- Akerstedt H
- Akesson TPA
- Akimoto G
- Akimov AV
- Alberghi GL
- Albert J
- Albrand S
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Alimonti G
- Alio L
- Alison J
- Allbrooke BMM
- Allison LJ
- Allport PP
- Aloisio A
- Alonso A
- Alonso F
- Alpigiani C
- Altheimer A
- Alviggi MG
- Amako K
- Amelung C
- Amidei D
- Amorim A
- Amoroso S
- Amram N
- Amundsen G
- Anastopoulos C
- Ancu LS
- Andari N
- Andeen T
- Anders G
- Andersb CF
- Anderson KJ
- Andreazza A
- Andrei V
- Anduaga XS
- Angelidakis S
- Angelozzi I
- Anger P
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- Anghinolfi F
- Anh TV
- Anisenkov AV
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- Annovi A
- Antonaki A
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- Armadans RC
- Armbruster AJ
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- Bagnaia P
- Bai Y
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- Baker OK
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- Bannoura AAE
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- Barnett BM
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- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
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Search for nonpointing and delayed photons in the diphoton and missing transverse momentum final state in 8 TeV pp collisions at the LHC using the ATLAS detector
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- Youssef S
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- Yusuff I
- Zabinski B
- Zaidan R
- Zaitsev AM
- Zaman A
- Zambito S
- Zanello L
- Zanzi D
- Zeitnitz C
- Zeman M
- Zemla A
- Zengel K
- Zenin O
- Zenis T
- Zerwas D
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- Zhao Z
- Zhemchugov A
- Zhong J
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- Zhukov K
- Zibell A
- Zieminska D
- Zimine NI
- Zimmermann C
- Zimmermann R
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- Zinonos Z
- Ziolkowski M
- Zobernig G
- Zoccoli A
- Zurzolo G
- Zutshi V
- Zwalinski L
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2014
- Field of study
A search has been performed, using the full 20.3 fb−1 data sample of 8 TeV proton-proton collisions collected in 2012 with the ATLAS detector at the LHC, for photons originating from a displaced vertex due to the decay of a neutral long-lived particle into a photon and an invisible particle. The analysis investigates the diphoton plus missing transverse momentum final state, and is therefore most sensitive to pair production of long-lived particles. The analysis technique exploits the capabilities of the ATLAS electromagnetic calorimeter to make precise measurements of the flight direction, as well as the time of flight, of photons. No excess is observed over the Standard Model predictions for background. Exclusion limits are set within the context of gauge mediated supersymmetry breaking models, with the lightest neutralino being the next-to-lightest supersymmetric particle and decaying into a photon and gravitino with a lifetime in the range from 250 ps to about 100 ns
Search for scalar diphoton resonances in the mass range 65-600 GeV with the ATLAS detector in pp collision data at √s = 8 TeV
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdinov O
- Aben R
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- Abramowicz H
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- Alberghi GL
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- Aleksandrov IN
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- Carrillo-Montoya GD
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- Carvalho J
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- Castanheira MTD
- Castelli A
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- Castillo LRF
- Castro NF
- Catastini P
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- Cattai A
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- Caughron S
- Cavaliere V
- Cavalli D
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- Cavasinni V
- Ceradini F
- Cerio B
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- Cerri A
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- Cetin SA
- Chafaq A
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- Chalupkova I
- Chang P
- Chapleau B
- Chapman JD
- Charfeddine D
- Charlton DG
- Chau CC
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- Ziolkowski M
- Zobernig G
- Zoccoli A
- zur Nedden M
- Zurzolo G
- Zutshi V
- Zwalinski L
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2014
- Field of study
A search for scalar particles decaying via narrow resonances into two photons in the mass range 65–600 GeV is performed using 20.3 fb−¹ of √s=8 TeV pp collision data collected with the ATLAS detector at the Large Hadron Collider. The recently discovered Higgs boson is treated as a background. No significant evidence for an additional signal is observed. The results are presented as limits at the 95% confidence level on the production cross section of a scalar boson times branching ratio into two photons, in a fiducial volume where the reconstruction efficiency is approximately independent of the event topology. The upper limits set extend over a considerably wider mass range than previous searches
Monitoring and data quality assessment of the ATLAS liquid argon calorimeter
- Author
- Aad G
- Abajyan T
- Abbott B
- Abdallah J
- Abdinov O
- Aben R
- Abi B
- Abolins M
- AbouZeid OS
- Abramowicz H
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- Publication venue
- Publication date
- 01/01/2014
- Field of study
The liquid argon calorimeter is a key component of the ATLAS detector installed at the CERN Large Hadron Collider. The primary purpose of this calorimeter is the measurement of electron and photon kinematic properties. It also provides a crucial input for measuring jets and missing transverse momentum. An advanced data monitoring procedure was designed to quickly identify issues that would affect detector performance and ensure that only the best quality data are used for physics analysis. This article presents the validation procedure developed during the 2011 and 2012 LHC data-taking periods, in which more than 98% of the proton-proton luminosity recorded by ATLAS at a centre-of-mass energy of 7-8 TeV had calorimeter data quality suitable for physics analysis
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