228 research outputs found
PENGARUH SARANA FISIK DAN KUALITAS PRODUK TERHADAP KEPUASAN KONSUME N PADA KOPI ANGKRINGAN DAGO
ABSTRAK
Penelitian ini bertujuan untuk mengetahui pengaruh
Sarana Fisik
dan
Kualitas Produk terhadap Kepuasan Konsumen pada Kopi Angkringan Dago.
Rumusan masalah dalam penelitian ini adalah bagaimana tanggapan konsumen
tentang
Sarana Fisik
yang disediakan di Kopi Angkringan Dago, bagaimana
tanggapan konsumen tentang kualitas produk yang ditawarkan di Kopi
Angkringan Dago dan seberapa besar pengaruh
Sarana Fisik
dan kualitas produk
terhadap kepuasan konsumen di Kopi Angkringan Dago baik secar
a simultan
maupun parsial.
Metode yang digunakan penulis dalam penelitian ini adalah penelitian
deskriftif dan verifikatif dengan teknik pengumpulan data studi kepustakaan, studi
di lapangan, dan kuisioner. Adapun ukurang populasinya 3251 orang perbulan
de
ngan sampel yang diteliti adalah berjumlah 100 orang, sedangkan teknik
sampling yang digunakan untuk menghitung besarnya ukuran sampel adalah
non
-
probability
sampling
adalah metode
incidental sampling.
Sesuai dengan
perhitungan statistik,
sarana fisik
dan
kualitas produk memberikan kontribusi
terhadap kepuasan pelanggan pada Kopi Angkringan Dago sebesar 79,3%
sedangkan sisanya sebesar 20,7% merupakan pengaruh dari variabel lain yang
tidak diteliti.
Kata Kunci :
Sarana Fisik
, Kualitas Produk
dan Kepuasan Kon
sume
Accumulation of chromium metastable atoms into an Optical Trap
We report the fast accumulation of a large number of metastable 52Cr atoms in
a mixed trap, formed by the superposition of a strongly confining optical trap
and a quadrupolar magnetic trap. The steady state is reached after about 400
ms, providing a cloud of more than one million metastable atoms at a
temperature of about 100 microK, with a peak density of 10^{18} atoms.m^{-3}.
We have optimized the loading procedure, and measured the light shift of the
5D4 state by analyzing how the trapped atoms respond to a parametric
excitation. We compare this result to a theoretical evaluation based on the
available spectroscopic data for chromium atoms.Comment: 7 pages, 5 Figure
De bello gallico
Letra humanística. Huecos para iniciales. 30 líneas, en caja de 210 x 120 mmFoliación moderna en tinta. Tinta negra en el texto y algunas apostillas, roja en las cabeceras y la mayor parte de las apostillasEl primer y último fol. de cada cuadernillo en vitelaIncipit: "Commentariorum C. Iulii Caesaris de bello Gallico liber primvs incipit. Ivlivs Celsvs Constantinvs vir emendavit. Lege foeliciter. Gallia est omnis divisa in partes tres..." (fol. 1r)Explicit: "... Harum rerum litteris cognitis Romae dierum XX supplicatio indicitur" (fol. 104v)30800E-2 T-5 N-
TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits
Despite the success of genome-wide association studies (GWAS) in detecting a large number of loci for complex phenotypes such as rheumatoid arthritis (RA) susceptibility, the lack of information on the causal genes leaves important challenges to interpret GWAS results in the context of the disease biology. Here, we genetically fine-map the RA risk locus at 19p13 to define causal variants, and explore the pleiotropic effects of these same variants in other complex traits. First, we combined Immunochip dense genotyping (n = 23,092 case/control samples), Exomechip genotyping (n = 18,409 case/control samples) and targeted exon-sequencing (n = 2,236 case/controls samples) to demonstrate that three protein-coding variants in TYK2 (tyrosine kinase 2) independently protect against RA: P1104A (rs34536443, OR = 0.66, P = 2.3 x 10(-21)), A928V (rs35018800, OR = 0.53, P = 1.2 x 10(-9)), and I684S (rs12720356, OR = 0.86, P = 4.6 x 10(-7)). Second, we show that the same three TYK2 variants protect against systemic lupus erythematosus (SLE, Pomnibus = 6 x 10(-18)), and provide suggestive evidence that two of the TYK2 variants (P1104A and A928V) may also protect against inflammatory bowel disease (IBD; P(omnibus) = 0.005). Finally, in a phenome-wide association study (PheWAS) assessing \u3e500 phenotypes using electronic medical records (EMR) in \u3e29,000 subjects, we found no convincing evidence for association of P1104A and A928V with complex phenotypes other than autoimmune diseases such as RA, SLE and IBD. Together, our results demonstrate the role of TYK2 in the pathogenesis of RA, SLE and IBD, and provide supporting evidence for TYK2 as a promising drug target for the treatment of autoimmune diseases
C. Iulii Caesaris quae extant
Sign.: *8, A-Z12, 2A-2B12Port. grab. calc. con retr. de Julio César5 p. de grab. xil. con fortificaciones, 4 h. de grab. calc. con un map. de la Galia y otro de Hispani
Strange particle production in proton-proton collisions at TeV with ALICE at the LHC
The production of mesons containing strange quarks (K, ) and both
singly and doubly strange baryons (, Anti-, and
+Anti-) are measured at central rapidity in pp collisions at
= 0.9 TeV with the ALICE experiment at the LHC. The results are
obtained from the analysis of about 250 k minimum bias events recorded in 2009.
Measurements of yields (dN/dy) and transverse momentum spectra at central
rapidities for inelastic pp collisions are presented. For mesons, we report
yields () of 0.184 0.002 stat. 0.006 syst. for K and
0.021 0.004 stat. 0.003 syst. for . For baryons, we find
= 0.048 0.001 stat. 0.004 syst. for , 0.047
0.002 stat. 0.005 syst. for Anti- and 0.0101 0.0020 stat.
0.0009 syst. for +Anti-. The results are also compared with
predictions for identified particle spectra from QCD-inspired models and
provide a baseline for comparisons with both future pp measurements at higher
energies and heavy-ion collisions.Comment: 33 pages, 21 captioned figures, 10 tables, authors from page 28,
published version, figures at
http://aliceinfo.cern.ch/ArtSubmission/node/387
Los comentarios de Cayo Julio César
Contiene: Suplemento a los Comentarios de Cayo Julio César / entresacado y traducido en castellano de la vida del mismo César ; escrita en latín por Cayo Suetonio Tranquílo, y en griego por Plutarco el de Chersoneso. Con port. y págs. propiasAclaración del tít. tomado de antep.Sign.: []\p2\s, [estrella]\p8\s, B-Z\p4\s, 2A-2R\p4\s, []\p4\s, B-F\p4\s, G\p2\sAntep.Port. con grab. calc.: "Bon. Salesa del., P. Fontana sculp."La primera h. de grab. calc. es un retrato de Pompeyo : " Bon. Salesa del. , P. Bettelini sculp."Las h. de grab. pleg. calc. son map
Study of QGP signatures with the phi->K+K- signal in Pb-Pb ALICE events
The phi->K+K- decay channel in Pb-Pb collisions at LHC is studied through a
full simulation of the ALICE detector. The study focuses on possible signatures
in this channel of quark-gluon plasma (QGP) formation. On a basis of 10^6
collisions at high centrality some proposed QGP signatures are clearly visible
both in K+K- invariant mass and transverse mass distributions. The high
significance of this observation appears to reside heavily on the use of the
TOF (Time Of Flight) system of ALICE in addition to its central tracking
detectors.Comment: 9 pages, 7 figures, to appear in EPJ
Structural brain abnormalities in the common epilepsies assessed in a worldwide ENIGMA study
Progressive functional decline in the epilepsies is largely unexplained. We formed the ENIGMA-Epilepsy consortium to understand factors that influence brain measures in epilepsy, pooling data from 24 research centres in 14 countries across Europe, North and South America, Asia, and Australia. Structural brain measures were extracted from MRI brain scans across 2149 individuals with epilepsy, divided into four epilepsy subgroups including idiopathic generalized epilepsies (n =367), mesial temporal lobe epilepsies with hippocampal sclerosis (MTLE; left, n = 415; right, n = 339), and all other epilepsies in aggregate (n = 1026), and compared to 1727 matched healthy controls. We ranked brain structures in order of greatest differences between patients and controls, by meta-analysing effect sizes across 16 subcortical and 68 cortical brain regions. We also tested effects of duration of disease, age at onset, and age-by-diagnosis interactions on structural measures. We observed widespread patterns of altered subcortical volume and reduced cortical grey matter thickness. Compared to controls, all epilepsy groups showed lower volume in the right thalamus (Cohen's d = -0.24 to -0.73; P < 1.49 × 10-4), and lower thickness in the precentral gyri bilaterally (d = -0.34 to -0.52; P < 4.31 × 10-6). Both MTLE subgroups showed profound volume reduction in the ipsilateral hippocampus (d = -1.73 to -1.91, P < 1.4 × 10-19), and lower thickness in extrahippocampal cortical regions, including the precentral and paracentral gyri, compared to controls (d = -0.36 to -0.52; P < 1.49 × 10-4). Thickness differences of the ipsilateral temporopolar, parahippocampal, entorhinal, and fusiform gyri, contralateral pars triangularis, and bilateral precuneus, superior frontal and caudal middle frontal gyri were observed in left, but not right, MTLE (d = -0.29 to -0.54; P < 1.49 × 10-4). Contrastingly, thickness differences of the ipsilateral pars opercularis, and contralateral transverse temporal gyrus, were observed in right, but not left, MTLE (d = -0.27 to -0.51; P < 1.49 × 10-4). Lower subcortical volume and cortical thickness associated with a longer duration of epilepsy in the all-epilepsies, all-other-epilepsies, and right MTLE groups (beta, b < -0.0018; P < 1.49 × 10-4). In the largest neuroimaging study of epilepsy to date, we provide information on the common epilepsies that could not be realistically acquired in any other way. Our study provides a robust ranking of brain measures that can be further targeted for study in genetic and neuropathological studies. This worldwide initiative identifies patterns of shared grey matter reduction across epilepsy syndromes, and distinctive abnormalities between epilepsy syndromes, which inform our understanding of epilepsy as a network disorder, and indicate that certain epilepsy syndromes involve more widespread structural compromise than previously assumed
Measurement of D+- and D0 production in deep inelastic scattering using a lifetime tag at HERA
The production of D-+/-- and D-0-mesons has been measured with the ZEUS detector at HERA using an integrated luminosity of 133.6 pb(-1). The measurements cover the kinematic range 5 < Q(2) < 1000 GeV2, 0.02 < y < 0.7, 1.5 < p(T)(D) < 15 GeV and |eta(D)| < 1.6. Combinatorial background to the D-meson signals is reduced by using the ZEUS microvertex detector to reconstruct displaced secondary vertices. Production cross sections are compared with the predictions of next-to-leading-order QCD, which is found to describe the data well. Measurements are extrapolated to the full kinematic phase space in order to obtain the open-charm contribution, F-2(c (c) over bar), to the proton structure function, F-2
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