The Hidden Intentions of Eliade? - Re-reading Critiques of Eliade from the Perspective of Eliade`s Expectation of the History of Religions -

Within the last several years, we have been inundated with books and articles continuing the argument between Eliade's criticizers and his disciples. Many criticisms of Eliade focus on the so-called hidden intentions of his scholarly. work. First, criticizers allege that Eliade's work contains his ominous political and social views. Second, Eliade's opponents argue that Eliade's work reflects the "Western construction of Religion." It is necessary and appropriate to understand Eliade's work in relation to his historical and social views: not only. have many contemporary scholars acknowledged Eliade's influence both as a scholar and as a public figure, Eliade himself also articulated his mission as one of responding to social and political issues. However, this paper will assert that Eliade's scholarly work should not be marginalized by the reckless conjecture of his political and social intentions by his opponents. As will be shown, Eliade's opponents argument of "Western construction of Religion" itself is based on the Western-centered academic tradition that has been ignorant of Eastern religious traditions. In contrast, the personal, academic, and historical background of Eliade's belief in the unity of the human mind and his respect for the East will be seen as foundational to understanding his work

Updated Rice Kinase Database RKD 2.0: enabling transcriptome and functional analysis of rice kinase genes

Rice kinases with biotic stress responses. (XLSX 28 kb

Compressed representation of a partially defined integer function over multiple arguments

In OLAP (OnLine Analitical Processing) data are analysed in an n-dimensional cube. The cube may be represented as a partially defined function over n arguments. Considering that often the function is not defined everywhere, we ask: is there a known way of representing the function or the points in which it is defined, in a more compact manner than the trivial one

Natural Form of Noncytolytic Flexible Human Fc as a Long-Acting Carrier of Agonistic Ligand, Erythropoietin

Human IgG1 Fc has been widely used as a bioconjugate, but exhibits shortcomings, such as antibody- and complement-mediated cytotoxicity as well as decreased bioactivity, when applied to agonistic proteins. Here, we constructed a nonimmunogenic, noncytolytic and flexible hybrid Fc (hyFc) consisting of IgD and IgG4, and tested its function using erythropoietin (EPO) conjugate, EPO-hyFc. Despite low amino acid homology (20.5%) between IgD Fc and IgG4 Fc, EPO-hyFc retained “Y-shaped” structure and repeated intravenous administrations of EPO-hyFc into monkeys did not generate EPO-hyFc-specific antibody responses. Furthermore, EPO-hyFc could not bind to FcγR I and C1q in contrast to EPO-IgG1 Fc. In addition, EPO-hyFc exhibited better in vitro bioactivity and in vivo bioactivity in rats than EPO-IgG1 Fc, presumably due to the high flexibility of IgD. Moreover, the mean serum half-life of EPO-hyFc(H), a high sialic acid content form of EPO-hyFc, was approximately 2-fold longer than that of the heavily glycosylated EPO, darbepoetin alfa, in rats. More importantly, subcutaneous injection of EPO-hyFc(H) not only induced a significantly greater elevation of serum hemoglobin levels than darbepoetin alfa in both normal rats and cisplatin-induced anemic rats, but also displayed a delayed time to maximal serum level and twice final area-under-the-curve (AUClast). Taken together, hyFc might be a more attractive Fc conjugate for agonistic proteins/peptides than IgG1 Fc due to its capability to elongate their half-lives without inducing host effector functions and hindering bioactivity of fused molecules. Additionally, a head-to-head comparison demonstrated that hyFc-fusion strategy more effectively improved the in vivo bioactivity of EPO than the hyperglycosylation approach

Study of double parton scattering using W+2-jet events in proton-proton collisions at √s=7 TeV

Peer reviewe

Search for new physics in the multijet and missing transverse momentum final state in proton-proton collisions at √s=8 Tev

Peer reviewe

Measurement of Higgs boson production and properties in the WW decay channel with leptonic final states

Peer reviewe