The palynology of selected Ordovician localities in Scotland

Ordovician samples have been collected from various places from within three separate terranes in Scotland; the Highland Border Complex, the Southern Uplands and the Midland Valley. The samples have been palynologically processed and their assemblages studied with the aim of understanding some of the palaeoecological, biostratigraphical and thermal relationships of the three areas.Seventy one samples have been processed from nine localities of the Highland Border Complex and these have yielded fifteen species of chitinozoans in four genera, as well as indeterminate species of those genera. There are also five species of acritarchs in four genera as well as other microfossils. Black shales from the Complex yield the most diverse palynomorph assemblages, and were probably deposited from Arenig through to Caradoc although not necessarily at the same time in different parts of the basin. The preservation of palynomorphs appears to be better in the west of Scotland than in the east.From the Southern Uplands samples have been processed from Coldingham Bay and proved barren, from Barrhill the assemblages are poor, but from the Ordovician-Silurian bondary beds (C. peltifer to P. acuminatus Zones) at Dob's Linn they are quite diverse although abundance is very low, with forty three samples yielding thirty three species of acritarchs in eighteen genera, thirty one species of chitinozoans in thirteen genera and various other microfossils. The boundary cannot be delineated using the palynological assemblages, and although Tylotopalla sp. A and Ancyrochitina ancyrea Eisenack 1931 are common in most of the samples from the boundary the palynomorphs do not appear to mirror the changes that occur in the graptolite assemblages.From the Midland Valley samples have been processed from eight miscellaneous localities in the region of Girvan, giving very little biostratigraphical data, although one sample from Doularg Hill is dated as upper Arenig to lower Llanvirn. A section of twelve samples processed from the Mill and Shalloch Formations (D. complanatus and D. anceps Zones) at Woodland Point, Girvan, has yielded thirty five species of chitinozoans in twelve genera including a new species Angochitina woodlandensis and five new combinations; Belonechitina comma (Eisenack 1959), Belonechitina hirsuta (Laufeld 1967). Belonechitina micracantha (Eisenack 1931), Belonechitina schopfi subsp. americana (Taugourdeau 1965), and Belonechitina seriespinosa (Jenkins 1969). There are also forty seven species of acritarchs in twentyone genera, including two new species; Actinotodissus woodlandense, and Goniosphaeridium girvanense, and many scolecodonts. Spores are common and three species are recognised at Woodland Point. The samples are dated as Upper Ordovician and Calpichitina lenticularis (Bouche 1965) and Acanthochitina barbata appear to be important Upper Ordovician indicators, possibly being near-shore species as they are not found in rocks of the same age at Dob's Linn. Calpichitina lenticularis is very important in one sample and less so in all the others and it is suggested that it may be reworked. The palaeoecological picture at Woodland point shows an offshore situation in the Mill Formation, becoming more near-shore at the base of the Shalloch Formation and then more off-shore again.The palaeoecology of both Dob's Linn and Woodland Point are discussed and chitinozoans found to be more common in black shales than grey mudstones, although the acritarchs do not appear to be preferentially found in grey mudstones or black shales. Netromorph acritarchs are less common at Dob's Linn than was expected, but are very common at Woodland Point which may suggest that the sediments at Woodland Point were deposited more offshore than those at Dob's Linn but were more greatly influenced by turbiditic material. Sphaeromorph acritarchs at Woodland Point are very common and due to the variable thickness of the walls it is suggested that there is a mixing of near-shore and off-shore species, possibly by the turbiditic action mentioned above. Belonechitina is markedlymore important at Woodland Point than at Dob's Linn the reverse of which is true with Cyathochitina . The suggested reason for this is that Belonechitina is a near-shore species whilst Cyathochitina is an off-shore species. Veryhachium appears to become more important towards the end of the Ordovician, as a sample each from Woodland Point and Dob's Linn contain three species of this relatively rare genus, although the significance of this is not yet known.The sample from Dob's Linn and Woodland Point are compared with published works using the jacquard Coefficient and the results presented. The samples at Dob's Linn are compared with the Ordovician-Silurian boundary sediments elsewhere, and although different species are present at Dob's Linn and on Anticosti Island, and the abundance and diversity is lower at Dob's Linn, the boundary in Scotland has a much better palynomorph assemblage than was expected. The boundary assemblage presented here is quite similar to the one in Skane, Sweden.Finally the thermal history of the samples is discussed, and a general trend appears, with the samples from Girvan being the least altered, those from the Southern Uplands being moderately altered and finally the Highland Border Complex samples which have been subjected to temperatures probably between 200 and 300oC, and thus strongly altered

The Use of Meteorlogical Data to Improve Contrail Detection in Thermal Imagery over Ireland.

Aircraft induced contrails have been found to have a net warming influence on the climate system, with strong regional dependence. Persistent linear contrails are detectable in 1 Km thermal imagery and, using an automated Contrail Detection Algorithm (CDA), can be identified on the basis of their different properties at the 11 and 12 m w av.el enTgthshe algorithm s ability to distinguish contrails from other linear features depends on the sensitivity of its tuning parameters. In order to keep the number of false identifications low, the algorithm imposes strict limits on contrail size, linearity and intensity. This paper investigates whether including additional information (i.e. meteorological data) within the CDA may allow for these criteria to be less rigorous, thus increasing the contrail-detection rate, without increasing the false alarm rate

Sensitivity of predicted bioaerosol exposure from open windrow composting facilities to ADMS dispersion model parameters

Bioaerosols are released in elevated quantities from composting facilities and are associated with negative health effects, although dose-response relationships are not well understood, and require improved exposure classification. Dispersion modelling has great potential to improve exposure classification, but has not yet been extensively used or validated in this context. We present a sensitivity analysis of the ADMS dispersion model specific to input parameter ranges relevant to bioaerosol emissions from open windrow composting. This analysis provides an aid for model calibration by prioritising parameter adjustment and targeting independent parameter estimation. Results showed that predicted exposure was most sensitive to the wet and dry deposition modules and the majority of parameters relating to emission source characteristics, including pollutant emission velocity, source geometry and source height. This research improves understanding of the accuracy of model input data required to provide more reliable exposure predictions

Protection induced by simultaneous subcutaneous and endobronchial vaccination with BCG/BCG and BCG/adenovirus expressing antigen 85A against Mycobacterium bovis in cattle

The incidence of bovine tuberculosis (bTB) in the GB has been increasing since the 1980s. Immunisation, alongside current control measures, has been proposed as a sustainable measure to control bTB. Immunisation with Mycobacterium bovis bacillus Calmette-Guerin (BCG) has been shown to protect against bTB. Furthermore, much experimental data indicates that pulmonary local immunity is important for protection against respiratory infections including Mycobacterium tuberculosis and that pulmonary immunisation is highly effective. Here, we evaluated protection against M. bovis, the main causative agent of bTB, conferred by BCG delivered subcutaneously, endobronchially or by the new strategy of simultaneous immunisation by both routes. We also tested simultaneous subcutaneous immunisation with BCG and endobronchial delivery of a recombinant type 5 adenovirus expressing mycobacterial antigen 85A. There was significantly reduced visible pathology in animals receiving the simultaneous BCG/BCG or BCG/Ad85 treatment compared to naïve controls. Furthermore, there were significantly fewer advanced microscopic granulomata in animals receiving BCG/Ad85A compared to naive controls. Thus, combining local and systemic immunisation limits the development of pathology, which in turn could decrease bTB transmission

Rapid synchronous type 1 IFN and virus-specific T cell responses characterize first wave non-severe SARS-CoV-2 infections

Effective control of SARS-CoV-2 infection on primary exposure may reveal correlates of protective immunity to future variants, but we lack insights into immune responses before or at the time virus is first detected. We use blood transcriptomics, multiparameter flow cytometry, and T cell receptor (TCR) sequencing spanning the time of incident non-severe infection in unvaccinated virus-naive individuals to identify rapid type 1 interferon (IFN) responses common to other acute respiratory viruses and cell proliferation responses that discriminate SARS-CoV-2 from other viruses. These peak by the time the virus is first detected and sometimes precede virus detection. Cell proliferation is most evident in CD8 T cells and associated with specific expansion of SARS-CoV-2-reactive TCRs, in contrast to virus-specific antibodies, which lag by 1–2 weeks. Our data support a protective role for early type 1 IFN and CD8 T cell responses, with implications for development of universal T cell vaccines

The Ninth Data Release of the Sloan Digital Sky Survey: First Spectroscopic Data from the SDSS-III Baryon Oscillation Spectroscopic Survey

The Sloan Digital Sky Survey III (SDSS-III) presents the first spectroscopic data from the Baryon Oscillation Spectroscopic Survey (BOSS). This ninth data release (DR9) of the SDSS project includes 535,995 new galaxy spectra (median z=0.52), 102,100 new quasar spectra (median z=2.32), and 90,897 new stellar spectra, along with the data presented in previous data releases. These spectra were obtained with the new BOSS spectrograph and were taken between 2009 December and 2011 July. In addition, the stellar parameters pipeline, which determines radial velocities, surface temperatures, surface gravities, and metallicities of stars, has been updated and refined with improvements in temperature estimates for stars with T_eff<5000 K and in metallicity estimates for stars with [Fe/H]>-0.5. DR9 includes new stellar parameters for all stars presented in DR8, including stars from SDSS-I and II, as well as those observed as part of the SDSS-III Sloan Extension for Galactic Understanding and Exploration-2 (SEGUE-2). The astrometry error introduced in the DR8 imaging catalogs has been corrected in the DR9 data products. The next data release for SDSS-III will be in Summer 2013, which will present the first data from the Apache Point Observatory Galactic Evolution Experiment (APOGEE) along with another year of data from BOSS, followed by the final SDSS-III data release in December 2014.Comment: 9 figures; 2 tables. Submitted to ApJS. DR9 is available at http://www.sdss3.org/dr

The Fourteenth Data Release of the Sloan Digital Sky Survey: First Spectroscopic Data from the extended Baryon Oscillation Spectroscopic Survey and from the second phase of the Apache Point Observatory Galactic Evolution Experiment

The fourth generation of the Sloan Digital Sky Survey (SDSS-IV) has been in operation since July 2014. This paper describes the second data release from this phase, and the fourteenth from SDSS overall (making this, Data Release Fourteen or DR14). This release makes public data taken by SDSS-IV in its first two years of operation (July 2014-2016). Like all previous SDSS releases, DR14 is cumulative, including the most recent reductions and calibrations of all data taken by SDSS since the first phase began operations in 2000. New in DR14 is the first public release of data from the extended Baryon Oscillation Spectroscopic Survey (eBOSS); the first data from the second phase of the Apache Point Observatory (APO) Galactic Evolution Experiment (APOGEE-2), including stellar parameter estimates from an innovative data driven machine learning algorithm known as "The Cannon"; and almost twice as many data cubes from the Mapping Nearby Galaxies at APO (MaNGA) survey as were in the previous release (N = 2812 in total). This paper describes the location and format of the publicly available data from SDSS-IV surveys. We provide references to the important technical papers describing how these data have been taken (both targeting and observation details) and processed for scientific use. The SDSS website (www.sdss.org) has been updated for this release, and provides links to data downloads, as well as tutorials and examples of data use. SDSS-IV is planning to continue to collect astronomical data until 2020, and will be followed by SDSS-V.Comment: SDSS-IV collaboration alphabetical author data release paper. DR14 happened on 31st July 2017. 19 pages, 5 figures. Accepted by ApJS on 28th Nov 2017 (this is the "post-print" and "post-proofs" version; minor corrections only from v1, and most of errors found in proofs corrected

Sloan Digital Sky Survey IV: Mapping the Milky Way, Nearby Galaxies, and the Distant Universe

We describe the Sloan Digital Sky Survey IV (SDSS-IV), a project encompassing three major spectroscopic programs. The Apache Point Observatory Galactic Evolution Experiment 2 (APOGEE-2) is observing hundreds of thousands of Milky Way stars at high resolution and high signal-to-noise ratios in the near-infrared. The Mapping Nearby Galaxies at Apache Point Observatory (MaNGA) survey is obtaining spatially resolved spectroscopy for thousands of nearby galaxies (median $z\sim 0.03$). The extended Baryon Oscillation Spectroscopic Survey (eBOSS) is mapping the galaxy, quasar, and neutral gas distributions between $z\sim 0.6$ and 3.5 to constrain cosmology using baryon acoustic oscillations, redshift space distortions, and the shape of the power spectrum. Within eBOSS, we are conducting two major subprograms: the SPectroscopic IDentification of eROSITA Sources (SPIDERS), investigating X-ray AGNs and galaxies in X-ray clusters, and the Time Domain Spectroscopic Survey (TDSS), obtaining spectra of variable sources. All programs use the 2.5 m Sloan Foundation Telescope at the Apache Point Observatory; observations there began in Summer 2014. APOGEE-2 also operates a second near-infrared spectrograph at the 2.5 m du Pont Telescope at Las Campanas Observatory, with observations beginning in early 2017. Observations at both facilities are scheduled to continue through 2020. In keeping with previous SDSS policy, SDSS-IV provides regularly scheduled public data releases; the first one, Data Release 13, was made available in 2016 July

Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in 25 723 PrCa cases and 26 274 controls of European ancestry. We detected evidence for multiple independent signals at 16 regions, 12 of which contained additional newly identified significant associations. A single signal comprising a spectrum of correlated variation was observed at 39 regions; 35 of which are now described by a novel more significantly associated lead SNP, while the originally reported variant remained as the lead SNP only in 4 regions. We also confirmed two association signals in Europeans that had been previously reported only in East-Asian GWAS. Based on statistical evidence and linkage disequilibrium (LD) structure, we have curated and narrowed down the list of the most likely candidate causal variants for each region. Functional annotation using data from ENCODE filtered for PrCa cell lines and eQTL analysis demonstrated significant enrichment for overlap with bio-features within this set. By incorporating the novel risk variants identified here alongside the refined data for existing association signals, we estimate that these loci now explain ∼38.9% of the familial relative risk of PrCa, an 8.9% improvement over the previously reported GWAS tag SNPs. This suggests that a significant fraction of the heritability of PrCa may have been hidden during the discovery phase of GWAS, in particular due to the presence of multiple independent signals within the same regio

The Fourteenth Data Release of the Sloan Digital Sky Survey: First Spectroscopic Data from the Extended Baryon Oscillation Spectroscopic Survey and from the Second Phase of the Apache Point Observatory Galactic Evolution Experiment

The fourth generation of the Sloan Digital Sky Survey (SDSS-IV) has been in operation since 2014 July. This paper describes the second data release from this phase, and the 14th from SDSS overall (making this Data Release Fourteen or DR14). This release makes the data taken by SDSS-IV in its first two years of operation (2014–2016 July) public. Like all previous SDSS releases, DR14 is cumulative, including the most recent reductions and calibrations of all data taken by SDSS since the first phase began operations in 2000. New in DR14 is the first public release of data from the extended Baryon Oscillation Spectroscopic Survey; the first data from the second phase of the Apache Point Observatory (APO) Galactic Evolution Experiment (APOGEE-2), including stellar parameter estimates from an innovative data-driven machine-learning algorithm known as "The Cannon"; and almost twice as many data cubes from the Mapping Nearby Galaxies at APO (MaNGA) survey as were in the previous release (N = 2812 in total). This paper describes the location and format of the publicly available data from the SDSS-IV surveys. We provide references to the important technical papers describing how these data have been taken (both targeting and observation details) and processed for scientific use. The SDSS web site (www.sdss.org) has been updated for this release and provides links to data downloads, as well as tutorials and examples of data use. SDSS-IV is planning to continue to collect astronomical data until 2020 and will be followed by SDSS-V