Remarks, AICPA Spring Council Meeting, Boca Raton, Florida, May 1, 1972

https://egrove.olemiss.edu/aicpa_assoc/2083/thumbnail.jp

Analysis of the Tax reform Act of 1969

https://egrove.olemiss.edu/aicpa_guides/1650/thumbnail.jp

Ribosomal 18S rRNA base pairs with mRNA during eukaryotic translation initiation

International audienceEukaryotic mRNAs often contain a Kozak sequence that helps tether the ribosome to the AUG start codon. The mRNA of histone H4 (h4) does not undergo classical ribosome scanning but has evolved a specific tethering mechanism. The cryo-EM structure of the rabbit ribosome complex with mouse h4 shows that the mRNA forms a folded, repressive structure at the mRNA entry site on the 40S subunit next to the tip of helix 16 of 18S ribosomal RNA (rRNA). Toe-printing and mutational assays reveal that an interaction exists between a purine-rich sequence in h4 mRNA and a complementary UUUC sequence of helix h16. Together the present data establish that the h4 mRNA harbours a sequence complementary to an 18S rRNA sequence which tethers the mRNA to the ribosome to promote proper start codon positioning, complementing the interactions of the 40S subunit with the Kozak sequence that flanks the AUG start codon

Evidence-based vegetation management : prospects and challenges

The effect of applied vegetation science on society has the potential to increaseby adopting an evidence-based approach. However, this would require a shift infocus towards effect size and results suitable formeta-analyses, a focus on practitionersas potential readers, more emphasis on practical problems rather thanmechanism, and an acceptance of all well-executed experimental studies, evenif confirmatory. Thus, the prevailing editorial policies need to be reconsidered,as well as the methods of analysing, reporting and evaluating research, for ourresearch efforts to be of better use within society