PLEA BARGAINING: A PANACEA TOWARDS PRISON DECONGESTION IN NIGERIA

Against the panoramic view of the criminal justice reform agenda in Nigeria, the plea bargaining procedure is yet to be fully recognized as a major intervention strategy to deal with the problems in the Nigerian criminal justice administration. This paper therefore conceptualized the concept of plea bargaining. The legal basis for plea, the justifications for plea as well as the merits and demerits of the plea are discussed. The paper also highlights the major problems afflicting criminal justice administration and examines the steps being taken to deal with the problems. The emphasis is on strengthening arguments for a mutual acceptance of plea bargaining as a credible exist strategy by both the state and an alleged offender. The way forward in form of recommendations for the expansion and institutionalization of the practice is also discussed.

PROCESS OPTIMIZATION OF OIL EXPRESSION FROM WATERMELON (CITRULLUS LANATUS) SEEDS

Watermelon fruit contains large quantities of seeds and these seeds are under-utilized. It contains reasonable amount of oil (22%) which if expressed will serve as vegetable oil for human consumption or biodiesel for powering agricultural machines and boost the income of the farmers. The main objective of this research work is to study the interaction effect of operating parameters on the mechanical oil expression from the seed. The variables considered include applied pressure (85.00, 90.00, 95.00, 100.00 and 105.00 kN/mm2), roasting temperature (70.00, 80.00, 90.00, 100 and 110 °C) and moisture content (6.00, 8.00, 10.00, 12.00 and 14.00 %). A total sum of 20 batch experiments were carried out and the maximum oil yield was 13.49% (at corresponding moisture content of 6.00%, roasting temperature of 85.00oC and applied pressure of 105.00 kN/mm2 respectively) and minimum oil yield obtained was 9.41%.(at corresponding moisture content of 14.00%, roasting temperature 80 °C and applied pressure of 85.00 kN/mm2 respectively). While the optimum oil yield of 12.42% was obtained from the expression at corresponding moisture content of 6.00%, roasting temperature of 80.00ºC, and applied pressure of 105.00 kN/mm2. The result showed that the three independent variables had significant effect on oil yield and regression model equation was developed to predict the oil yield from watermelon seeds at known variables

Exposure to known COVID-19 infection risk factors among healthcare workers responding to COVID-19 outbreak in Lagos State, Nigeria-2020

Introduction: Globally, over 790,000 deaths of COVID-19 cases were reported by August 20, 2020, these numbers included healthcare workers (HCW). The high infection rate among HCW to COVID-19 is worrisome requiring countries to protect them. We examined the risk of exposure among HCW. Methods: We conducted a cross-sectional study among 151 healthcare workers responding to the COVID-19 outbreak in Lagos State using an electronic-based self-administered questionnaire. Categorical variables were summarized as proportions, and bivariate analysis of the independent and dependent variables was subjected to the Chi-square test. A P-value of < 0.05 was considered statistically significant. Results: Sixty-nine (45.9%) of responders have had over 10-year experience in the health sector. Ninety-eight (64.9%) of the responders had previous experience in responding to outbreaks. Ninety-nine (65.6%) of responders had been involved in the COVID-19 response beyond two months. Sixty-three (41.7%) participants were exposed to aerosol-generating procedures (AGP), with the majority (85%) occurring during the collection of sputum for COVID-19 testing. Forty-three percent were involved directly with facilities where confirmed cases were treated. Among responders, 101 (66.9%) admitted to the regular use of work-appropriate personal protective equipment (PPE) during their activities. One hundred and thirty-seven HCW (90.7%) had no exposure to biological or respiratory fluids. On bivariate analysis, no variable was associated with the risk of contracting the infection by healthcare workers. Conclusion: The exposure to known COVID-19 risk factors among healthcare responders in Lagos is high. This exposure is not associated with years of experience of service in the health sector, age or gender of responders, direct contact with confirmed cases, or direct care of confirmed COVID-19 cases

Social Media Efficacy on Prevention and Control of Covid-19 Pandemic in Ilorin South Local Government Area, Kwara State

This study investigated social media efficacy on prevention and control of Covid – 19 pandemic in Ilorin South Local Government Area, Kwara State, Nigeria. This study examines the effectiveness of awareness created by Facebook, NCDC messages, and Twitter on prevention and control of Covid – 19 pandemic in Ilorin South LGA, Kwara State. The study adopted a descriptive research design of survey type. A multi-stage sampling technique of stratified and purposive techniques was employed to select 150 respondents for the study. A structured questionnaire was validated and pilot tested with the use of test re-test reliability method and 0.75r were obtained. The findings revealed that awareness created through Facebook, NCDC, and Twitter has many impacts on the prevention and control of the Covid – 19 pandemic. Based on these findings, the study recommends that health officers should encourage people on the need to use social media tools like Facebook, NCDC messages, Twitter, Youtube and soon to gain insight on prevention and control of Covid – 19 pandemic

Numerical Analysis of Natural Convection in a Concentric Trapezoidal Enclosure Filled with a Porous Medium

The natural convection around a heated trapezoidal block of different sizes positioned centrically in a larger trapezium has been investigated numerically. The annulus between the trapeziums is occupied by porous media. The sides of the inner trapezium are heated to a fixed temperature and the slanted walls of the outer trapezium are isolated thermally. In contrast, its upper and lower walls are heated uniformly. The pertinent dimensionless equations were solved with COMSOL Multiphysics 5.6. The parameters considered are modified Rayleigh number, Darcy number, and area ratio. The results of this study are shown as isothermal contours, stream functions, and average Nusselt number. The results show that increasing the modified Rayleigh number improves heat transfer; however, the response of the thermal profiles to area ratio increment depends on the range of Darcy number considered. This study finds application in ingot treatments and microchannel cooling, among others

Dichlorvos Induced AChE Inhibition in Discrete Brain Regions and the Neuro-Cognitive Implications: Ameliorative Effect of Nigella Sativa

Background: There has been a rise in accidental poisoning cases resulting from the indiscriminate use and exposure to Dichlorvos (DDVP), especially in developing countries, and no antidote with satisfactory efficacy is currently available. Thus, we investigated the AChE reactivation potential of Nigella sativa oil (NSO) following DDVP induced AChE inhibition patterns in the brain and the associated cognitive implications. Methods: Fourty Wistar rats were randomly divided into four groups of 10 each.; The controls were administered PBS (1 ml/kg); DDVP (8.8 mg/kg) was given to the experimental group I; while DDVP+NSO (8.8 mg/kg + 1 ml/kg) and NSO (1 ml/kg) was administered orally to the experimental groups II and III respectively. All treatments lasted for 14 consecutive days. Morris Water Maze (MWM) paradigm was used to assess the working memory, then rats were euthanized, the brain excised, three brains were fixed for histological examination (Nissl staining), and the other seven brains were homogenized for AChE activity and Ca2+ concentrations. Data were analyzed statistically, using ANOVA method and P values of ≤0.05 was considered as significant. Results: In this study, DDVP differentially inhibited AChE activities in various brain regions: cerebellum (86.1%), hippocampus (40.6%), frontal cortex (33.2%), medulla (21.5%), spinal cord (14.8%), and occipital cortex (8.9%). It reduced Ca2+ concentration, but had no effect on the delayed escape latency in the MWM, nor impaired the neuro-architectures. NSO caused increased AChE activities, Ca2+ concentration and reduced escape latency, and improved histologic architectures. Conclusion: We concluded that NSO reactivated DDVP-induced AChE inhibition and improved memory indices, thus, it may serve as a potential treatment in the management of DDVP poisoning cases

Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Background Regularly updated data on stroke and its pathological types, including data on their incidence, prevalence, mortality, disability, risk factors, and epidemiological trends, are important for evidence-based stroke care planning and resource allocation. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) aims to provide a standardised and comprehensive measurement of these metrics at global, regional, and national levels. Methods We applied GBD 2019 analytical tools to calculate stroke incidence, prevalence, mortality, disability-adjusted life-years (DALYs), and the population attributable fraction (PAF) of DALYs (with corresponding 95% uncertainty intervals [UIs]) associated with 19 risk factors, for 204 countries and territories from 1990 to 2019. These estimates were provided for ischaemic stroke, intracerebral haemorrhage, subarachnoid haemorrhage, and all strokes combined, and stratified by sex, age group, and World Bank country income level. Findings In 2019, there were 12·2 million (95% UI 11·0–13·6) incident cases of stroke, 101 million (93·2–111) prevalent cases of stroke, 143 million (133–153) DALYs due to stroke, and 6·55 million (6·00–7·02) deaths from stroke. Globally, stroke remained the second-leading cause of death (11·6% [10·8–12·2] of total deaths) and the third-leading cause of death and disability combined (5·7% [5·1–6·2] of total DALYs) in 2019. From 1990 to 2019, the absolute number of incident strokes increased by 70·0% (67·0–73·0), prevalent strokes increased by 85·0% (83·0–88·0), deaths from stroke increased by 43·0% (31·0–55·0), and DALYs due to stroke increased by 32·0% (22·0–42·0). During the same period, age-standardised rates of stroke incidence decreased by 17·0% (15·0–18·0), mortality decreased by 36·0% (31·0–42·0), prevalence decreased by 6·0% (5·0–7·0), and DALYs decreased by 36·0% (31·0–42·0). However, among people younger than 70 years, prevalence rates increased by 22·0% (21·0–24·0) and incidence rates increased by 15·0% (12·0–18·0). In 2019, the age-standardised stroke-related mortality rate was 3·6 (3·5–3·8) times higher in the World Bank low-income group than in the World Bank high-income group, and the age-standardised stroke-related DALY rate was 3·7 (3·5–3·9) times higher in the low-income group than the high-income group. Ischaemic stroke constituted 62·4% of all incident strokes in 2019 (7·63 million [6·57–8·96]), while intracerebral haemorrhage constituted 27·9% (3·41 million [2·97–3·91]) and subarachnoid haemorrhage constituted 9·7% (1·18 million [1·01–1·39]). In 2019, the five leading risk factors for stroke were high systolic blood pressure (contributing to 79·6 million [67·7–90·8] DALYs or 55·5% [48·2–62·0] of total stroke DALYs), high body-mass index (34·9 million [22·3–48·6] DALYs or 24·3% [15·7–33·2]), high fasting plasma glucose (28·9 million [19·8–41·5] DALYs or 20·2% [13·8–29·1]), ambient particulate matter pollution (28·7 million [23·4–33·4] DALYs or 20·1% [16·6–23·0]), and smoking (25·3 million [22·6–28·2] DALYs or 17·6% [16·4–19·0]). Interpretation The annual number of strokes and deaths due to stroke increased substantially from 1990 to 2019, despite substantial reductions in age-standardised rates, particularly among people older than 70 years. The highest age-standardised stroke-related mortality and DALY rates were in the World Bank low-income group. The fastest-growing risk factor for stroke between 1990 and 2019 was high body-mass index. Without urgent implementation of effective primary prevention strategies, the stroke burden will probably continue to grow across the world, particularly in low-income countries.publishedVersio

Mapping 123 million neonatal, infant and child deaths between 2000 and 2017

Since 2000, many countries have achieved considerable success in improving child survival, but localized progress remains unclear. To inform efforts towards United Nations Sustainable Development Goal 3.2—to end preventable child deaths by 2030—we need consistently estimated data at the subnational level regarding child mortality rates and trends. Here we quantified, for the period 2000–2017, the subnational variation in mortality rates and number of deaths of neonates, infants and children under 5 years of age within 99 low- and middle-income countries using a geostatistical survival model. We estimated that 32% of children under 5 in these countries lived in districts that had attained rates of 25 or fewer child deaths per 1,000 live births by 2017, and that 58% of child deaths between 2000 and 2017 in these countries could have been averted in the absence of geographical inequality. This study enables the identification of high-mortality clusters, patterns of progress and geographical inequalities to inform appropriate investments and implementations that will help to improve the health of all populations

Burden of injury along the development spectrum : associations between the Socio-demographic Index and disability-adjusted life year estimates from the Global Burden of Disease Study 2017

Background The epidemiological transition of non-communicable diseases replacing infectious diseases as the main contributors to disease burden has been well documented in global health literature. Less focus, however, has been given to the relationship between sociodemographic changes and injury. The aim of this study was to examine the association between disability-adjusted life years (DALYs) from injury for 195 countries and territories at different levels along the development spectrum between 1990 and 2017 based on the Global Burden of Disease (GBD) 2017 estimates. Methods Injury mortality was estimated using the GBD mortality database, corrections for garbage coding and CODEm-the cause of death ensemble modelling tool. Morbidity estimation was based on surveys and inpatient and outpatient data sets for 30 cause-of-injury with 47 nature-of-injury categories each. The Socio-demographic Index (SDI) is a composite indicator that includes lagged income per capita, average educational attainment over age 15 years and total fertility rate. Results For many causes of injury, age-standardised DALY rates declined with increasing SDI, although road injury, interpersonal violence and self-harm did not follow this pattern. Particularly for self-harm opposing patterns were observed in regions with similar SDI levels. For road injuries, this effect was less pronounced. Conclusions The overall global pattern is that of declining injury burden with increasing SDI. However, not all injuries follow this pattern, which suggests multiple underlying mechanisms influencing injury DALYs. There is a need for a detailed understanding of these patterns to help to inform national and global efforts to address injury-related health outcomes across the development spectrum.Peer reviewe

Estimating global injuries morbidity and mortality : methods and data used in the Global Burden of Disease 2017 study

Background: While there is a long history of measuring death and disability from injuries, modern research methods must account for the wide spectrum of disability that can occur in an injury, and must provide estimates with sufficient demographic, geographical and temporal detail to be useful for policy makers. The Global Burden of Disease (GBD) 2017 study used methods to provide highly detailed estimates of global injury burden that meet these criteria. Methods: In this study, we report and discuss the methods used in GBD 2017 for injury morbidity and mortality burden estimation. In summary, these methods included estimating cause-specific mortality for every cause of injury, and then estimating incidence for every cause of injury. Non-fatal disability for each cause is then calculated based on the probabilities of suffering from different types of bodily injury experienced. Results: GBD 2017 produced morbidity and mortality estimates for 38 causes of injury. Estimates were produced in terms of incidence, prevalence, years lived with disability, cause-specific mortality, years of life lost and disability-adjusted life-years for a 28-year period for 22 age groups, 195 countries and both sexes. Conclusions: GBD 2017 demonstrated a complex and sophisticated series of analytical steps using the largest known database of morbidity and mortality data on injuries. GBD 2017 results should be used to help inform injury prevention policy making and resource allocation. We also identify important avenues for improving injury burden estimation in the future