El mito y el arraigo: usos fabulosos del territorio, de la Provenza al Caribe

El artículo presenta un análisis comparatista de dos obras de Gabriel García Márquez y de Jean Giono, quienes comparten un ambiguo arraigo a la tierra natal: la colección de cuentos La increíble y triste historia de la cándida Eréndira y de su abuela desalmada, y la novela El canto del mundo. Plantea la relación entre el espacio referencial – la Provenza y el Caribe – en el cual se criaron los autores y el espacio ficcional que recrean en sus textos, analizando el proceso de ficcionalización del territorio y la singularidad del espacio literario

Stratigraphie, sédimentologie et magnétostratigraphie du site oldowayen de Fejej FJ-1, Sud-Omo, Ethiopie : premiers résultats

Le gisement oldowayen FJ-1 de Fejej est situé dans le sud-ouest de l’Ethiopie, près de la basse vallée de l’Omo et à proximité de la rive orientale du lac Turkana. La stratigraphie du site FJ-1 est divisée en 5 ensembles qui témoignent de dépôts fluviatiles ou de plaine d’inondation et d’une activité volcanique régionale. Les analyses granulométriques indiquent que le transport avant le dépôt des sédiments a été de courte durée. La minéralogie montre clairement que les principales sources des sédiments sont le socle métamorphique de la chaîne Hamar et le haut plateau basaltique, situés au nord-est de la zone d’étude. La combinaison de ces analyses montre que le transport a été essentiellement assuré par un affluent de la rivière Omo. Les mesures du paléomagnétisme effectuées sur toute la stratigraphie du gisement ont permis de situer le site FJ-1 dans un événement positif. L’apport des autres études telles que la paléontologie, la téphrochronologie et les datations RPE sur quartz blanchis permettent d’attribuer celui-ci à l’évènement d’Olduvai et au niveau archéologique C1 un âge compris entre 1,96 et 1,90 Ma.The FJ-1 site of Fejej is located in the south-western most part of Ethiopia near the lower Omo valley, on the eastern side of Lake Turkana. The FJ-1 site’s stratigraphy is divided into 5 members deposited by river bed and flood plain sediments and a regional volcanic event. Morphoscopic and granulometric studies show that the transport of sediment was brief and the mineralogy has revealed that sediments originated from the metamorphic Hamar Range and from the High Plateau, both located to the northeast of Fejej. Sedimentological studies indicate that transport was essentially assured by a tributary of the Omo River. Palaeomagnetic measurements indicate the positive Olduvai event. The contribution of palaeontology and radiometric dating indicates that the age of the C1 archaeological horizon is between 1,96 and 1,90 Ma

Early T Cell Signalling Is Reversibly Altered in PD-1+ T Lymphocytes Infiltrating Human Tumors

To improve cancer immunotherapy, a better understanding of the weak efficiency of tumor-infiltrating T lymphocytes (TIL) is necessary. We have analyzed the functional state of human TIL immediately after resection of three types of tumors (NSCLC, melanoma and RCC). Several signalling pathways (calcium, phosphorylation of ERK and Akt) and cytokine secretion are affected to different extents in TIL, and show a partial spontaneous recovery within a few hours in culture. The global result is an anergy that is quite distinct from clonal anergy induced in vitro, and closer to adaptive tolerance in mice. PD-1 (programmed death -1) is systematically expressed by TIL and may contribute to their anergy by its mere expression, and not only when it interacts with its ligands PD-L1 or PD-L2, which are not expressed by every tumor. Indeed, the TCR-induced calcium and ERK responses were reduced in peripheral blood T cells transfected with PD-1. Inhibition by sodium stibogluconate of the SHP-1 and SHP-2 phosphatases that associate with several inhibitory receptors including PD-1, relieves part of the anergy apparent in TIL or in PD-1-transfected T cells. This work highlights some of the molecular modifications contributing to functional defects of human TIL

Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis

Search for heavy resonances decaying to two Higgs bosons in final states containing four b quarks

A search is presented for narrow heavy resonances X decaying into pairs of Higgs bosons (H) in proton-proton collisions collected by the CMS experiment at the LHC at root s = 8 TeV. The data correspond to an integrated luminosity of 19.7 fb(-1). The search considers HH resonances with masses between 1 and 3 TeV, having final states of two b quark pairs. Each Higgs boson is produced with large momentum, and the hadronization products of the pair of b quarks can usually be reconstructed as single large jets. The background from multijet and t (t) over bar events is significantly reduced by applying requirements related to the flavor of the jet, its mass, and its substructure. The signal would be identified as a peak on top of the dijet invariant mass spectrum of the remaining background events. No evidence is observed for such a signal. Upper limits obtained at 95 confidence level for the product of the production cross section and branching fraction sigma(gg -> X) B(X -> HH -> b (b) over barb (b) over bar) range from 10 to 1.5 fb for the mass of X from 1.15 to 2.0 TeV, significantly extending previous searches. For a warped extra dimension theory with amass scale Lambda(R) = 1 TeV, the data exclude radion scalar masses between 1.15 and 1.55 TeV

Search for supersymmetry in events with one lepton and multiple jets in proton-proton collisions at root s=13 TeV

Peer reviewe

Measurement of the top quark forward-backward production asymmetry and the anomalous chromoelectric and chromomagnetic moments in pp collisions at √s = 13 TeV

Abstract The parton-level top quark (t) forward-backward asymmetry and the anomalous chromoelectric (d̂ t) and chromomagnetic (μ̂ t) moments have been measured using LHC pp collisions at a center-of-mass energy of 13 TeV, collected in the CMS detector in a data sample corresponding to an integrated luminosity of 35.9 fb−1. The linearized variable AFB(1) is used to approximate the asymmetry. Candidate t t ¯ events decaying to a muon or electron and jets in final states with low and high Lorentz boosts are selected and reconstructed using a fit of the kinematic distributions of the decay products to those expected for t t ¯ final states. The values found for the parameters are AFB(1)=0.048−0.087+0.095(stat)−0.029+0.020(syst),μ̂t=−0.024−0.009+0.013(stat)−0.011+0.016(syst), and a limit is placed on the magnitude of | d̂ t| < 0.03 at 95% confidence level. [Figure not available: see fulltext.

Measurement of the top quark mass using charged particles in pp collisions at root s=8 TeV

Peer reviewe

Measurement of t(t)over-bar normalised multi-differential cross sections in pp collisions at root s=13 TeV, and simultaneous determination of the strong coupling strength, top quark pole mass, and parton distribution functions

Peer reviewe

An embedding technique to determine ττ backgrounds in proton-proton collision data

An embedding technique is presented to estimate standard model tau tau backgrounds from data with minimal simulation input. In the data, the muons are removed from reconstructed mu mu events and replaced with simulated tau leptons with the same kinematic properties. In this way, a set of hybrid events is obtained that does not rely on simulation except for the decay of the tau leptons. The challenges in describing the underlying event or the production of associated jets in the simulation are avoided. The technique described in this paper was developed for CMS. Its validation and the inherent uncertainties are also discussed. The demonstration of the performance of the technique is based on a sample of proton-proton collisions collected by CMS in 2017 at root s = 13 TeV corresponding to an integrated luminosity of 41.5 fb(-1).Peer reviewe