Z-boson as "the standard candle" for high precision W-boson physics at LHC

In this paper we propose a strategy for measuring the inclusive W-boson production processes at LHC. This strategy exploits simultaneously the unique flexibility of the LHC collider in running variable beam particle species at variable beam energies, and the configuration flexibility of the LHC detectors. We propose their concrete settings for a precision measurement of the Standard Model parameters. These dedicated settings optimise the use of the Z boson and Drell-Yan pair production processes as ``the standard reference candles''. The presented strategy allows to factorise and to directly measure those of the QCD effects which affect differently the W and Z production processes. It reduces to a level of 10^{-4} the impact of uncertainties in the partonic distribution functions (PDFs) and in the transverse momentum of the quarks on the measurement precision. Last but not the least, it reduces by a factor of 10 an impact of systematic measurement errors, such as the energy scale and the measurement resolution, on the W-boson production observables.Comment: 20 pages, 4 figure

The correction of the littlest Higgs model to the Higgs production process e−γ→νeW−He^{-}\gamma\to \nu_{e}W^{-}H in e−γe^{-}\gamma collisions

The littlest Higgs model is the most economical one among various little Higgs models. In the context of the littlest Higgs(LH) model, we study the process $e^{-}\gamma\to \nu_{e}W^{-}H$ and calculate the contributions of the LH model to the cross section of this process. The results show that, in most of parameter spaces preferred by the electroweak precision data, the value of the relative correction is larger than 10%. Such correction to the process $e^{-}\gamma\to \nu_{e}W^{-}H$ is large enough to be detected via $e^{-}\gamma$ collisions in the future high energy linear $e^{+}e^{-}$ collider($LC$) experiment with the c.m energy $\sqrt{s}$=500 GeV and a yearly integrated luminosity $\pounds=100fb^{-1}$, which will give an ideal way to test the model.Comment: 13 pages, 4 figure

Measurement of MW+ - MW- at LHC

This paper is the second of the series of papers proposing dedicated strategies for precision measurements of the Standard Model parameters at the LHC. The common feature of these strategies is their robustness with respect to the systematic measurement and modeling error sources. Their impact on the precision of the measured parameters is reduced using dedicated observables and dedicated measurement procedures which exploit flexibilities of the collider and detector running modes. In the present paper we focus our attention on the measurement of the charge asymmetry of the W-boson mass. This measurement is of primordial importance for the LHC experimental program, both as a direct test of the charge-sign-independent coupling of the W-bosons to the matter particles and as a necessary first step towards the precision measurement of the charge-averaged W-boson mass. We propose and evaluate the LHC-specific strategy to measure the mass difference between the positively and negatively charged W-bosons, MW+ - MW-. We show that its present precision can be improved at the LHC by a factor of 20. We argue that such a precision is beyond the reach of the standard measurement and calibration methods imported to the LHC from the Tevatron program.Comment: 39 pages, 8 figure

Solar wind pressure pulse‐driven magnetospheric vortices and their global consequences

We report the in situ observation of a plasma vortex induced by a solar wind dynamic pressure enhancement in the nightside plasma sheet using multipoint measurements from Time History of Events and Macroscale Interactions during Substorms (THEMIS) satellites. The vortex has a scale of 5–10 Re and propagates several Re downtail, expanding while propagating. The features of the vortex are consistent with the prediction of the Sibeck (1990) model, and the vortex can penetrate deep (~8 Re ) in the dawn‐dusk direction and couple to field line oscillations. Global magnetohydrodynamics simulations are carried out, and it is found that the simulation and observations are consistent with each other. Data from THEMIS ground magnetometer stations indicate a poleward propagating vortex in the ionosphere, with a rotational sense consistent with the existence of the vortex observed in the magnetotail. Key Points Solar wind pressure pulse‐driven vortex was observed in the magnetosphere Simulation and ground magnetic field data confirm this tailward moving vortex The vortex can penetrate deep inside the tail plasma sheet and couple to FLRsPeer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/107999/1/jgra51112.pd

Immersed boundary-finite element model of fluid-structure interaction in the aortic root

It has long been recognized that aortic root elasticity helps to ensure efficient aortic valve closure, but our understanding of the functional importance of the elasticity and geometry of the aortic root continues to evolve as increasingly detailed in vivo imaging data become available. Herein, we describe fluid-structure interaction models of the aortic root, including the aortic valve leaflets, the sinuses of Valsalva, the aortic annulus, and the sinotubular junction, that employ a version of Peskin's immersed boundary (IB) method with a finite element (FE) description of the structural elasticity. We develop both an idealized model of the root with three-fold symmetry of the aortic sinuses and valve leaflets, and a more realistic model that accounts for the differences in the sizes of the left, right, and noncoronary sinuses and corresponding valve cusps. As in earlier work, we use fiber-based models of the valve leaflets, but this study extends earlier IB models of the aortic root by employing incompressible hyperelastic models of the mechanics of the sinuses and ascending aorta using a constitutive law fit to experimental data from human aortic root tissue. In vivo pressure loading is accounted for by a backwards displacement method that determines the unloaded configurations of the root models. Our models yield realistic cardiac output at physiological pressures, with low transvalvular pressure differences during forward flow, minimal regurgitation during valve closure, and realistic pressure loads when the valve is closed during diastole. Further, results from high-resolution computations demonstrate that IB models of the aortic valve are able to produce essentially grid-converged dynamics at practical grid spacings for the high-Reynolds number flows of the aortic root

First Observation and Measurement of the Decay K+- -> pi+- e+ e- gamma

Using the full data set of the NA48/2 experiment, the decay K+- -> pi+- e+ e- gamma is observed for the first time, selecting 120 candidates with 7.3 +- 1.7 estimated background events. With K+- -> pi+- pi0D as normalisation channel, the branching ratio is determined in a model-independent way to be Br(K+- -> pi+- e+ e- gamma, m_eegamma > 260 MeV/c^2) = (1.19 +- 0.12_stat +- 0.04_syst) x 10^-8. This measured value and the spectrum of the e+ e- gamma invariant mass allow a comparison with predictions of Chiral Perturbation Theory.Comment: 13 pages, 3 figures. Accepted for publication in Phys.Lett.

VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma

Inactivation of the von Hippel-Lindau (VHL) E3 ubiquitin ligase protein is a hallmark of clear cell renal cell carcinoma (ccRCC). Identifying how pathways affected by VHL loss contribute to ccRCC remains challenging. We used a genome-wide in vitro expression strategy to identify proteins that bind VHL when hydroxylated. Zinc fingers and homeoboxes 2 (ZHX2) was found as a VHL target, and its hydroxylation allowed VHL to regulate its protein stability. Tumor cells from ccRCC patients with VHL loss-of-function mutations usually had increased abundance and nuclear localization of ZHX2. Functionally, depletion of ZHX2 inhibited VHL-deficient ccRCC cell growth in vitro and in vivo. Mechanistically, integrated chromatin immunoprecipitation sequencing and microarray analysis showed that ZHX2 promoted nuclear factor κB activation. These studies reveal ZHX2 as a potential therapeutic target for ccRCC

Spin dynamics in semiconductors

This article reviews the current status of spin dynamics in semiconductors which has achieved a lot of progress in the past years due to the fast growing field of semiconductor spintronics. The primary focus is the theoretical and experimental developments of spin relaxation and dephasing in both spin precession in time domain and spin diffusion and transport in spacial domain. A fully microscopic many-body investigation on spin dynamics based on the kinetic spin Bloch equation approach is reviewed comprehensively.Comment: a review article with 193 pages and 1103 references. To be published in Physics Reports

Measurement of the Atmospheric Muon Spectrum from 20 to 3000 GeV

The absolute muon flux between 20 GeV and 3000 GeV is measured with the L3 magnetic muon spectrometer for zenith angles ranging from 0 degree to 58 degree. Due to the large exposure of about 150 m2 sr d, and the excellent momentum resolution of the L3 muon chambers, a precision of 2.3 % at 150 GeV in the vertical direction is achieved. The ratio of positive to negative muons is studied between 20 GeV and 500 GeV, and the average vertical muon charge ratio is found to be 1.285 +- 0.003 (stat.) +- 0.019 (syst.).Comment: Total 32 pages, 9Figure