A Predictive Model of Postnatal Surgical Intervention in Children With Prenatally Detected Congenital Anomalies of the Kidney and Urinary Tract

The aim of this study was to identify predictive factors and develop a model to assess individualized risk of postnatal surgical intervention in patients with antenatal hydronephrosis. This is a retrospective cohort study of 694 infants with prenatally detected congenital anomalies of kidney and urinary tract with a median follow-up time of 37 months. The main event of interest was postnatal surgical intervention. A predictive model was developed using Cox model with internal validation by bootstrap technique. Of 694 patients, 164 (24%) infants underwent surgical intervention in a median age of 7.8 months. Predictors of the surgical intervention in the model were: baseline glomerular filtration rate, associated hydronephrosis, presence of renal damage and the severity of renal pelvic dilatation. The optimism corrected c statistic for the model was 0.84 (95%CI, 0.82–0.87). The predictive model may contribute to identify infants at high risk for surgical intervention. Further studies are necessary to validate the model in patients from other settings

Towards a common future: revising the evolution of university-based sustainability research literature

The field of sustainability has evolved considerably since the report “Our Common Future” was published in 1987. Whereas matters related to sustainable development used to be of marginal interest in the 1980s, it has substantially evolved since, and have become mainstream. As a result, there is a plethora of research on different aspects, whose focus has also been influenced by societal developments. This line of thinking also applies to sustainability research in higher education, a special and central field. Unfortunately, the variety of research on matters of sustainable development in universities makes it difficult to obtain an insight into its current status, and to ascertain how it has evolved since 1987. Based on the perceived need to fill this gap, a study focusing on the evolution of university-based sustainability research literature has been undertaken. The study entailed approximately 1700 papers published between 1987 and 2019,  being one of the most comprehensive studies on this field ever undertaken. Apart from performing a bibliometric analysis using science mapping software tools, the research clustered the research into some key areas. The results suggest that, whereas impressive, the evolution of university-based sustainability research has been uneven, and calls for a more balanced emphasis to as to cover some research areas which have so far been neglected. The implications of this work are twofold: it will support the further development of the university-based sustainability research literature, and will help to address some thematic gaps, which are seen today, and to which greater attention is needed