Biomarkers of Nutrition for Development (BOND)—Iron Review

This is the fifth in the series of reviews developed as part of the Biomarkers of Nutrition for Development (BOND) program. The BOND Iron Expert Panel (I-EP) reviewed the extant knowledge regarding iron biology, public health implications, and the relative usefulness of currently available biomarkers of iron status from deficiency to overload. Approaches to assessing intake, including bioavailability, are also covered. The report also covers technical and laboratory considerations for the use of available biomarkers of iron status, and concludes with a description of research priorities along with a brief discussion of new biomarkers with potential for use across the spectrum of activities related to the study of iron in human health. The I-EP concluded that current iron biomarkers are reliable for accurately assessing many aspects of iron nutrition. However, a clear distinction is made between the relative strengths of biomarkers to assess hematological consequences of iron deficiency versus other putative functional outcomes, particularly the relationship between maternal and fetal iron status during pregnancy, birth outcomes, and infant cognitive, motor and emotional development. The I-EP also highlighted the importance of considering the confounding effects of inflammation and infection on the interpretation of iron biomarker results, as well as the impact of life stage. Finally, alternative approaches to the evaluation of the risk for nutritional iron overload at the population level are presented, because the currently designated upper limits for the biomarker generally employed (serum ferritin) may not differentiate between true iron overload and the effects of subclinical inflammation

An economic and legal assessment of the EU food industry's competitiveness

The objective of this article is to assess the competitiveness of the European food industry from an economic and legal perspective. Knowledge of its present competitiveness and improvement opportunities are lacking. To close this knowledge gap, we measured the competitiveness of eight subsectors, benchmarked them with four leading world economies, assessed the effect of differences in legal requirements, and predicted future developments using scenario analysis. International economics indicators supplemented with data on legal issues from a survey conducted by leading experts were used to measure competitiveness. The results show that the EU food industry's competitiveness is weak. The legal system was positively evaluated compared to the U.S. system, but major improvements are possible. The recommendations are to improve economies of scale, economies of scope, ICT-based supply chain management, and exploit cultural differences through innovation, within a more flexible and streamlined legal framework. [Econlit. Citations:F14, L66; Q13]. © 2008 Wiley Periodicals, Inc.