88 research outputs found
AutoLaparo: A New Dataset of Integrated Multi-tasks for Image-guided Surgical Automation in Laparoscopic Hysterectomy
- Publication venue
- Publication date
- 03/08/2022
- Field of study
Computer-assisted minimally invasive surgery has great potential in
benefiting modern operating theatres. The video data streamed from the
endoscope provides rich information to support context-awareness for
next-generation intelligent surgical systems. To achieve accurate perception
and automatic manipulation during the procedure, learning based technique is a
promising way, which enables advanced image analysis and scene understanding in
recent years. However, learning such models highly relies on large-scale,
high-quality, and multi-task labelled data. This is currently a bottleneck for
the topic, as available public dataset is still extremely limited in the field
of CAI. In this paper, we present and release the first integrated dataset
(named AutoLaparo) with multiple image-based perception tasks to facilitate
learning-based automation in hysterectomy surgery. Our AutoLaparo dataset is
developed based on full-length videos of entire hysterectomy procedures.
Specifically, three different yet highly correlated tasks are formulated in the
dataset, including surgical workflow recognition, laparoscope motion
prediction, and instrument and key anatomy segmentation. In addition, we
provide experimental results with state-of-the-art models as reference
benchmarks for further model developments and evaluations on this dataset. The
dataset is available at https://autolaparo.github.io.Comment: Accepted at MICCAI 202
Ad hoc influenza vaccination during years of significant antigenic drift in a tropical city with 2 seasonal peaks
- Author
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 01/05/2016
- Field of study
We evaluated the acceptability of an additional ad hoc influenza vaccination among the health care professionals following seasons with significant antigenic drift. Self-administered, anonymous surveys were performed by hard copy questionnaires in public hospitals, and by an on-line platform available to all healthcare professionals, from April 1st to May 31st, 2015. A total of 1290 healthcare professionals completed the questionnaires, including doctors, nurses, and allied health professionals working in both the public and private systems. Only 31.8% of participating respondents expressed an intention to receive the additional vaccine, despite that the majority of them agreed or strongly agreed that it would bring benefit to the community (88.9%), save lives (86.7%), reduce medical expenses (76.3%), satisfy public expectation (82.8%), and increase awareness of vaccination (86.1%). However, a significant proportion expressed concern that the vaccine could disturb the normal immunization schedule (45.5%); felt uncertain what to do in the next vaccination round (66.0%); perceived that the summer peak might not occur (48.2%); and believed that the summer peak might not be of the same virus (83.5%). Furthermore, 27.8% of all respondents expected that the additional vaccination could weaken the efficacy of previous vaccinations; 51.3% was concerned about side effects; and 61.3% estimated that there would be a low uptake rate. If the supply of vaccine was limited, higher priority groups were considered to include the elderly aged ≥65 years with chronic medical conditions (89.2%), the elderly living in residential care homes (87.4%), and long-stay residents of institutions for the disabled (80.7%). The strongest factors associated with accepting the additional vaccine included immunization with influenza vaccines in the past 3 years, higher perceived risk of contracting influenza, and higher perceived severity of the disease impact. The acceptability to an additional ad hoc influenza vaccination was low among healthcare professionals. This could have a negative impact on such additional vaccination campaigns since healthcare professionals are a key driver for vaccine acceptance. The discordance in perceived risk and acceptance of vaccination regarding self versus public deserves further evaluation
Interest-driven creator theory: towards a theory of learning design for Asia in the twenty-first century
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/12/2018
- Field of study
Asian education is known for its examination-driven orientation, with the downsides of distorting the processes of learning and teaching, diminishing students’ interest in learning, and failing to nurture twenty-first century competencies among students. As a group of Asian researchers, we have been developing Interest-Driven Creator (IDC) Theory, a design theory based on three anchored concepts, namely interest, creation, and habit. Each of these anchored concepts is represented by a loop composed of three components. In the interest loop, the three components are triggering, immersing, and extending. The components of the creation loop are imitating, combining, and staging. The habit loop consists of cuing environment, routine, and harmony. These three loops are interconnected in various ways, with their characteristics revealed by the design process. We hypothesize that technology-supported learning activities that are designed with reference to IDC Theory will enable students to develop interest in learning, be immersed in the creation process, and, by repeating this process in their daily routines, strengthen habits of creation. Furthermore, students will excel in learning performance, develop twenty-first century competencies, and become lifelong interest-driven creators. To sharpen our understanding and further the development of the theory, we need more discussion and collaborative efforts in the community. Hypotheses arising from this theory can be tested, revised, or refined by setting up and investigating IDC Theory-based experimental sites. By disseminating the framework, foundations, and practices to the various countries and regions of Asia, we hope that it will bring about compelling examples and hence a form of quality education for the twenty-first century, which is an alternative to the examination-driven education system. In this paper, we present an overall introduction to IDC Theory and its history, and discuss some of the steps for advancing it in the future
Identification of Human Papillomavirus Type 58 Lineages and the Distribution Worldwide
- Author
- Bae Jeong-Hoon
- Banks Lawrence
- Chan Paul K. S.
- Cheung Jo L. K.
- Cheung Tak-Hong
- Chirenje Mike Z.
- Chu Tang-Yuan
- Coutlee Francois
- De Marco Federico
- Di Stefano Rosa
- Ferrera Annabelle
- Fiander Alison N.
- Giovannelli Lucia
- Hibbitts Samantha
- Konno Ryo
- Luk Alfred C. S.
- Magure Tsitsi
- Moscicki Anna-Barbara
- Palefsky Joel M.
- Park Jong-Sup
- Picconi María Alejandra
- Pim David
- Pina-Sanchez Patricia
- Raiol Taina
- Settheetham-Ishida Wannapa
- Smith-McCune Karen K.
- Tsui Stephen K. W.
- Woo Yin-Ling
- Yu May M. Y.
- Publication venue
- Publication date
- 01/01/2011
- Field of study
Background. Human papillomavirus type 58 (HPV-58) accounts for a much higher proportion of cervical cancers in East Asia than other types. A classification system of HPV-58, which is essential for molecular epidemiological study, is lacking. Methods and results. This study analyzed the sequences of 401 isolates collected from 15 countries and cities. The 268 unique concatenated E6-E7-E2-E5-L1-LCR sequences that comprised 57% of the whole HPV-58 genome showed 4 distinct clusters. L1 and LCR produced tree topologies that best resembled the concatenated sequences and thus are the most appropriate surrogate regions for lineage classification. Moreover, short fragments from L1 (nucleotides 6014–6539) and LCR (nucleotides 7257–7429 and 7540–52) were found to contain sequence signatures informative for lineage identification. Lineage A was the most prevalent lineage across all regions. Lineage C was more frequent in Africa than elsewhere, whereas lineage D was more prevalent in Africa than in Asia. Among lineage A variants, sublineage A2 dominated in Africa, the Americas, and Europe, but not in Asia. Sublineage A1, which represents the prototype that originated from a patient with cancer, was rare worldwide except in Asia. Conclusions. HPV-58 can be classified into 4 lineages that show some degree of ethnogeographic predilection in distribution. The evolutionary, epidemiological, and pathological characteristics of these lineages warrant further study
Executive summary of the KDIGO 2021 Guideline for the Management of Glomerular Diseases.
- Author
- Adler Sharon G
- Barratt Jonathan
- Bridoux Frank
- Burdge Kelly A
- Chan Tak Mao
- Cheung Michael
- Cook H Terence
- Craig Jonathan C
- Earley Amy
- Fervenza Fernando C
- Floege Jürgen
- Gibson Keisha L
- Glassock Richard J
- Howell Martin
- Jayne David RW
- Jha Vivekanand
- Liew Adrian
- Liu Zhi-Hong
- Lytvyn Lyubov
- Mejía-Vilet Juan M
- Nester Carla M
- Radhakrishnan Jai
- Rave Elizabeth M
- Reich Heather N
- Ronco Pierre
- Rovin Brad H
- Sanders Jan-Stephan F
- Sethi Sanjeev
- Suzuki Yusuke
- Tang Sydney CW
- Tesar Vladimír
- Tonelli Marcello A
- Tunnicliffe David J
- Vivarelli Marina
- Wetzels Jack FM
- Publication venue
- Kidney Int
- Publication date
- 01/01/2021
- Field of study
The Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline for the Management of Glomerular Diseases is an update to the KDIGO 2012 guideline. The aim is to assist clinicians caring for individuals with glomerulonephritis (GN), both adults and children. The scope includes various glomerular diseases, including IgA nephropathy and IgA vasculitis, membranous nephropathy, nephrotic syndrome, minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), infection-related GN, antineutrophil cytoplasmic antibody (ANCA) vasculitis, lupus nephritis, and anti-glomerular basement membrane antibody GN. In addition, this guideline will be the first to address the subtype of complement-mediated diseases. Each chapter follows the same format providing guidance related to diagnosis, prognosis, treatment, and special situations. The goal of the guideline is to generate a useful resource for clinicians and patients by providing actionable recommendations based on evidence syntheses, with useful infographics incorporating views from experts in the field. Another aim is to propose research recommendations for areas where there are gaps in knowledge. The guideline targets a broad global audience of clinicians treating GN while being mindful of implications for policy and cost. Development of this guideline update followed an explicit process whereby treatment approaches and guideline recommendations are based on systematic reviews of relevant studies, and appraisal of the quality of the evidence and the strength of recommendations followed the "Grading of Recommendations Assessment, Development and Evaluation" (GRADE) approach. Limitations of the evidence are discussed, with areas of future research also presented
Geographical Distribution and Risk Association of Human Papillomavirus Genotype 52–Variant Lineages
- Author
- Burk Robert D
- Chan Martin C. W
- Chan Paul K. S.
- Chen Zigui
- Cheung Tak-Hong
- Chirenje Mike Z
- Chu Tang-Yuan
- Coutlée Francois
- De Marco Federico
- Fiander Alison N
- Giovannelli Lucia
- Grce Magdalena
- Hibbitts Samantha
- Ho Wendy C. S
- Konno Ryo
- Magure Tsitsi
- Moscicki Anna-Barbara
- Palefsky Joel M
- Park Jong-Sup
- Picconi María Alejandra
- Piña-Sánchez Patricia
- Sabol Ivan
- Settheetham-Ishida Wannapa
- Smith-McCune Karen K
- Wong Martin C. S
- Woo Yin-Ling
- Zhang Chuqing
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 30/05/2014
- Field of study
Human papillomavirus (HPV) genotype 52 is commonly found in Asian cases of cervical cancer but is rare elsewhere. Analysis of 611 isolates collected worldwide revealed a remarkable geographical distribution, with lineage B predominating in Asia (89.0% vs 0%–5.5% ; Pcorrected < .001), whereas lineage A predominated in Africa, the Americas, and Europe. We propose that the name “Asian lineage” be used to denote lineage B, to signify this feature. Preliminary analysis suggested a higher disease risk for lineage B, although ethnogeographical confounders could not be excluded. Further studies are warranted to verify whether the reported high attribution of disease to HPV52 in Asia is due to the high prevalence of lineage B
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Cause of Death and Predictors of All-Cause Mortality in Anticoagulated Patients With Nonvalvular Atrial Fibrillation : Data From ROCKET AF
- Author
- Abadier R.
- Abelson M.
- Abhyankar A.
- Abram N.
- Achimastos A.
- Agacdiken Agir A.
- Agah R.
- Agamasu J.
- Aganauskiene J.
- Ageno W.
- Agnelli G.
- Aguirre A.
- Ahuad Guerrero A.
- Aidietiene S.
- Aiub J.
- Akyea Djamson A.
- Al Saghir Y.
- Al Zoebi A.
- Albina G.
- Albirini A.
- Alcocer Gamba M.
- Alekseeva N.
- Alessi S.
- Alexeeva O.
- Alfieri A.
- Almaguer E.
- Almquist A.
- Altunkeser B.
- Alvarado O.
- Alvarez Garcia P.
- Alvarez Lopez H.
- Alvariqueta A.
- Alzaghrini G.
- Amaram S.
- Amerena J.
- Amosova K.
- Amuchastegui M.
- Anderson C.
- Anderson J.
- Andrews R.
- Angelova I.
- Antonios N.
- Antonishen M.
- Anusauskiene J.
- Archibald J.
- Arkhipov M.
- Aron G.
- Aroney G.
- Arouni A.
- Artis A.
- Arzola F.
- Ashchi M.
- Ata N.
- Avezum A.
- Awan N.
- Ayala Paredes F.
- Bacon J.
- Baek S.
- Balaguer J.
- Ballyzek M.
- Balparda C.
- Banerjee S.
- Banker D.
- Baranov A.
- Baranova E.
- Barbarash O.
- Barbarich V.
- Barber A.
- Barreto Filho J.
- Basart D.
- Basri H.
- Batalla E.
- Bath P.
- Batushkin V.
- Bauknecht C.
- Baumgartner R.
- Bayat J.
- Baños Velasco A.
- Becker R.
- Becker Richard C.
- Bedwell N.
- Behrens Humbold S.
- Behrens Spandau S.
- Belber A.
- Belenky D.
- Belgi A.
- Bell A.
- Beltran R.
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- Berg Johansen J.
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- Berlingieri J.
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- Bertolet B.
- Bessoudo R.
- Bester F.
- Bhagwat R.
- Bhamjee H.
- Bhesania T.
- Biedrzycka M.
- Bilsker M.
- Binetti G.
- Bladin C.
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- 01/01/2015
- Field of study
M. Kaste on työryhmän ROCKET AF Steering Comm jäsen.Background-Atrial fibrillation is associated with higher mortality. Identification of causes of death and contemporary risk factors for all-cause mortality may guide interventions. Methods and Results-In the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF) study, patients with nonvalvular atrial fibrillation were randomized to rivaroxaban or dose-adjusted warfarin. Cox proportional hazards regression with backward elimination identified factors at randomization that were independently associated with all-cause mortality in the 14 171 participants in the intention-to-treat population. The median age was 73 years, and the mean CHADS(2) score was 3.5. Over 1.9 years of median follow-up, 1214 (8.6%) patients died. Kaplan-Meier mortality rates were 4.2% at 1 year and 8.9% at 2 years. The majority of classified deaths (1081) were cardiovascular (72%), whereas only 6% were nonhemorrhagic stroke or systemic embolism. No significant difference in all-cause mortality was observed between the rivaroxaban and warfarin arms (P=0.15). Heart failure (hazard ratio 1.51, 95% CI 1.33-1.70, P= 75 years (hazard ratio 1.69, 95% CI 1.51-1.90, P Conclusions-In a large population of patients anticoagulated for nonvalvular atrial fibrillation, approximate to 7 in 10 deaths were cardiovascular, whereasPeer reviewe
Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector
- Author
- Aaboud Morad
- Aad Georges
- Abbott Brad
- Abdinov Ovsat
- Abeloos Baptiste
- Abidi Syed
- AbouZeid Ossama
- Abraham Nicola
- Abramowicz Halina
- Abreu Henso
- Abreu Ricardo
- Abulaiti Yiming
- Acharya Bobby
- Adachi Shunsuke
- Adamczyk Leszek
- Adelman Jahred
- Adersberger Michael
- Adye Tim
- Affolder Tony
- Afik Yoav
- Agatonovic-Jovin Tatjana
- Agheorghiesei Catalin
- Aguilar-Saavedra Juan
- Ahlen Steven
- Ahmadov Faig
- Aielli Giulio
- Akatsuka Shunichi
- Akerstedt Henrik
- Akilli Ece
- Akimov Andrei
- Alberghi Gian
- Albert Justin
- Albicocco Pietro
- Alconada Verzini Maria
- Alderweireldt Sara
- Aleksa Martin
- Aleksandrov Igor
- Alexa Calin
- Alexander Gideon
- Alexopoulos Theodoros
- Alhroob Muhammad
- Ali Babar
- Aliev Malik
- Alimonti Gianluca
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- Alkire Steven
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- Allen Benjamin
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- Aloisio Alberto
- Alonso Alejandro
- Alonso Francisco
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- Alshehri Azzah
- Alstaty Mahmoud
- Alvarez Gonzalez Barbara
- Alviggi Mariagrazia
- Amadio Brian
- Amaral Coutinho Yara
- Amelung Christoph
- Amidei Dante
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- Amoroso Simone
- Anastopoulos Christos
- Ancu Lucian
- Andari Nansi
- Andeen Timothy
- Anders Christoph
- Anders John
- Anderson Kelby
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- Angelidakis Stylianos
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- Angerami Aaron
- Anisenkov Alexey
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- Varol Tulin
- Varouchas Dimitris
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- Yamatani Masahiro
- Yamazaki Tomohiro
- Yamazaki Yuji
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- Zakharchuk Nataliia
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- Zanzi Daniele
- Zeitnitz Christian
- Zemaityte Gabija
- Zemla Andrzej
- Zeng Jian
- Zeng Qi
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- Zhang Dengfeng
- Zhang Dongliang
- Zhang Fangzhou
- Zhang Guangyi
- Zhang Huijun
- Zhang Jinlong
- Zhang Lei
- Zhang Liqing
- Zhang Matt
- Zhang Peng
- Zhang Rui
- Zhang Ruiqi
- Zhang Xueyao
- Zhang Yu
- Zhang Zhiqing
- Zhao Xiandong
- Zhao Yongke
- Zhao Zhengguo
- Zhemchugov Alexey
- Zhou Bing
- Zhou Chen
- Zhou Li
- Zhou Maosen
- Zhou Mingliang
- Zhou Ning
- Zhou You
- Zhu Cheng
- Zhu Hongbo
- Zhu Junjie
- Zhu Yingchun
- Zhuang Xuai
- Zhukov Konstantin
- Zibell Andre
- Zieminska Daria
- Zimine Nikolai
- Zimmermann Christoph
- Zimmermann Stephanie
- Zinonos Zinonas
- Zinser Markus
- Ziolkowski Michael
- Zobernig Georg
- Zoccoli Antonio
- Zou Rui
- zur Nedden Martin
- Zwalinski Lukasz
- Åkesson Torsten
- Šfiligoj Tina
- Ženiš Tibor
- Živković Lidija
- Άlvarez Piqueras Damián
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements
Search for gravitational-lensing signatures in the full third observing run of the LIGO-Virgo network
- Author
- Abbott R.
- Abe H.
- Acernese F.
- Ackley Kendall
- Adhicary S.
- Adhikari Naresh
- Adhikari Rana X.
- Adkins V. K.
- Adya V. B.
- Affeldt C.
- Agarwal D.
- Agathos Michalis
- Aguiar Odylio D.
- Aiello Lorenzo
- Ain A.
- Ajith Parameswaran
- Akutsu Tomotada
- Albanesi S.
- Alfaidi R. A.
- Allocca Annalisa
- Alléné C.
- Altin Paul
- Amato Alex
- Anand S.
- Ananyeva A.
- Anderson Stuart
- Anderson Warren G.
- Ando M.
- Andrade T.
- Andrea Prodi Giovanni
- Andres Nicolas
- Andric Tomislav
- Andrés-Carcasona Marc
- Anne Bizouard Marie
- Ansoldi S.
- Antelis Javier M.
- Antier Sarah
- Antonio Font Roda Jose
- Apostolatos T.
- Appavuravther E. Z.
- Appert S.
- Apple S. K.
- Arai Koji
- Araya Akito
- Araya Melody
- Areeda Joseph
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- Aritomi Naoki
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- Arogeti M.
- Aronson S. M.
- Arène M.
- Asada Hideki
- Ashton Gregory
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- Zhao Yue
- Zhao Yuhang
- Zheng Yanyan
- Zhou R.
- Zhu Xingjiang
- Zhu Zong-Hong
- Zimmerman Aaron
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- Árpád Gergely László
- 劉 國欽
- 曹周键
- 王谨
- 都丸 隆行
- Publication venue
- Publication date
- 01/04/2023
- Field of study
Gravitational lensing by massive objects along the line of sight to the source causes distortions of gravitational wave-signals; such distortions may reveal information about fundamental physics, cosmology and astrophysics. In this work, we have extended the search for lensing signatures to all binary black hole events from the third observing run of the LIGO--Virgo network. We search for repeated signals from strong lensing by 1) performing targeted searches for subthreshold signals, 2) calculating the degree of overlap amongst the intrinsic parameters and sky location of pairs of signals, 3) comparing the similarities of the spectrograms amongst pairs of signals, and 4) performing dual-signal Bayesian analysis that takes into account selection effects and astrophysical knowledge. We also search for distortions to the gravitational waveform caused by 1) frequency-independent phase shifts in strongly lensed images, and 2) frequency-dependent modulation of the amplitude and phase due to point masses. None of these searches yields significant evidence for lensing. Finally, we use the non-detection of gravitational-wave lensing to constrain the lensing rate based on the latest merger-rate estimates and the fraction of dark matter composed of compact objects
Observation of gravitational waves from the coalescence of a 2.5−4.5 M⊙ compact object and a neutron star
- Author
- Abac Adrian
- Abbott R.
- Abouelfettouh I.
- Acernese F.
- Ackley Kendall
- Adhicary S.
- Adhikari Naresh
- Adhikari Rana X.
- Adkins V. K.
- Afif Ismail M.
- Agarwal Deepali
- Agathos Michalis
- Aghaei Abchouyeh Maryam
- Aguiar Odylio D.
- Aguilar I.
- Aiello Lorenzo
- Ain Anirban
- Ajith Parameswaran
- Akcay Sarp
- Akseli Hannuksela Otto
- Akutsu Tomotada
- Al-Jodah Ammar
- Al-Shammari S.
- Albanesi Simone
- Alex iandolo Guido
- Alfaidi Reem Atallah E
- Allocca Annalisa
- Alléné C.
- Altin Paul
- Alvarez-Lopez Sofia
- Amato Alex
- Amez-Droz L.
- Amorosi A.
- Amra C.
- Ananyeva A.
- Anderson Stuart
- Anderson Warren G.
- Andia Manuel
- Ando M.
- Andrade T.
- Andrea Prodi Giovanni
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- Zweizig John
- Árpád Gergely László
- 劉 國欽
- 都丸 隆行
- Publication venue
- Publication date
- 23/04/2024
- Field of study
- …