Determining the Factors Influencing Cloud Computing Implementation in Library Management System (LMS): A High Order PLS-ANN Approach

The principal component of this paper is to ascertain the prominent variables of technological, organizational, environmental, and financial constructs that influence library cloud computing (LCC) among the library users and professionals in the selected universities of India. This paper discusses the advantages, opportunities, challenges, and Models of Smart Library in the ICT age library management system. The study also commissioned tools viz. EFA, CFA, and structural equation assess the degree to which selected factors were associated with LCC adoption. Empirical research proposed four hypotheses by selecting the technological, organizational, environmental, and financial constructs and 16 manifests in the specified model. The model was then tested on a sample of 510 respondents of 26 major states, central and private universities of India using SEM-ANN. First, SEM was employed to find out which variables had a meaningful influence on LCC. Secondly, the output of ANN outlined the rank of influencing predictors obtained from SEM. It is evident that technological factors, greater scalability (TF_1), tech-readiness (TF_2), and easier back-up (TF_3), are the most robust antecedents of LCC. Whereas in organizational factors- recognized usefulness (OF_1), are the robust manifest, but in environmental factors-geographical reach (EF_1), administrative support (EF_2), conducive application interface (EF_4), are the significant predictors. Eventually, financial factors- cost-saving (FF_1) and better return on investment (FF_2) are the considerable predictors obtained from ANN. The findings further indicate that behavioural intention to adopt the library cloud yielded novel insights that significantly benefit users and stakeholders

A Validated Stability-Indicating Liquid-Chromatographic Method for Ranitidine Hydrochloride in Liquid Oral Dosage Form

A selective, specific and stability-indicating gradient reverse phase high-performance liquid chromatographic (HPLC) method was developed for the determination of Ranitidine in presence of its impurities, forced degradation products and placebo substances such as saccharide and parabens. Ultraviolet detection was performed at 230 nm. Separate portions of the drug product and ingredients were exposed to stress conditions to induce oxidative, acidic, basic, hydrolytic, thermal and photolytic degradation. Ranitidine was found to degrade significantly at acidic, basic and oxidative stress conditions but was stable at heat and humidity. The developed method was validated as per International Conference on Harmonization (ICH) guidelines. The method was validated over this range for (i) system suitability (ii) specificity, (iii) precision, (iv) limit of detection and limit of quantification, (v) linearity, (vi) accuracy, (vii) robustness. The method was found to be precise, accurate, linear and robust. The proposed method was successfully employed for estimation of Ranitidine impurities in pharmaceutical preparations

Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

A double burden of malnutrition occurs when individuals, household members or communities experience both undernutrition and overweight. Here, we show geospatial estimates of overweight and wasting prevalence among children under 5 years of age in 105 low- and middle-income countries (LMICs) from 2000 to 2017 and aggregate these to policy-relevant administrative units. Wasting decreased overall across LMICs between 2000 and 2017, from 8.4% (62.3 (55.1–70.8) million) to 6.4% (58.3 (47.6–70.7) million), but is predicted to remain above the World Health Organization’s Global Nutrition Target of <5% in over half of LMICs by 2025. Prevalence of overweight increased from 5.2% (30 (22.8–38.5) million) in 2000 to 6.0% (55.5 (44.8–67.9) million) children aged under 5 years in 2017. Areas most affected by double burden of malnutrition were located in Indonesia, Thailand, southeastern China, Botswana, Cameroon and central Nigeria. Our estimates provide a new perspective to researchers, policy makers and public health agencies in their efforts to address this global childhood syndemic

Development and Validation of Q-Absorbance Ratio by UV-Spectrophotometric Method for Simultaneous Estimation of Metformin and Empagliflozin in Bulk and Combined Dosage Form

Advantages of simultaneous stability studies are the identification of new degradation products, to understand mutual induction and/or inhibition of rates of degradation and to analyze the degradation products of both drugs. Various ultraviolet spectroscopic and high performance liquid chromatographic assay methods were reported for the estimation of metformin, sitagliptin, pioglitazone, glimepiride and simvastatin individually and in combination with other drugs. All the above reported methods were based on the estimation of metformin, sitagliptin, pioglitazone, glimepiride and simvastatin alone or in combination with other drugs. The degradation products were generated and successfully separated by the developed and validated high performance liquid chromatographic methods for the estimation of the selected anti-diabetic drug combinations. The aim of the study was to develop and validate of Q-Absorbance Ratio UV-Spectrophotometric Method for Simultaneous Estimation of Metformin and Empagliflozin in Bulk and Combined Dosage Form. Keywords: Metformin, Method Development, Validation, Empagliflozin, UV-Spectrophotometer

JOP760665_Appendix – Supplemental material for Coffee with co-workers: role of caffeine on evaluations of the self and others in group settings

<p>Supplemental material, JOP760665_Appendix for Coffee with co-workers: role of caffeine on evaluations of the self and others in group settings by Vasu Unnava, Amit Surendra Singh and H. Rao Unnava in Journal of Psychopharmacology</p

PHM_Oct-Dec_11_3 march.pdf

Development and validation of a reverse phase-liquid chromatographic method for the estimation of butylated hydroxytoluene as antioxidant in paricalcitol hard gelatin capsule formulation dosage form Introduction: A novel and simple isocratic reverse phase liquid chromatographic (RP-LC) method was developed for the quantitative determination of antioxidantbutylated hydroxy toluene (BHT) in paricalcitol hard gelatin capsule. In the paricalcitol capsule BHT concentration is very low. This method is precisely able from paricalcitol main compound and other oil-based excipients. Materials and Methods: column with mobile phase containing a mixture of solvent A (water) and solvent B (methanol) in the ratio of 5:95 v/v, respectively. The flow rate was 0.8 mL/min with column temperature of 45°C and detection wavelength at 277 nm. The developed method was validated as per ICH guidelines with respect to specificity, linearity, limit of detection, limit of quantification, accuracy, precision and robustness. Results: In the precision study the % RSD for the result of BHT was below 1.5% at target with the correlation coefficient greater than 0.999 and % bias at 100% level are within + 2%. The percentage recoveries for BHT were calculated observed from 98.8 to 104.8%. Conclusion: The developed method was found to be precise, accurate, linear, selective and robust

Naturalized alien flora of the Indian states : biogeographic patterns, taxonomic structure and drivers of species richness

Despite an existing India-wide inventory of alien plant species, an inventory documenting the occurrence of naturalized alien plant species in each of the Indian states (including union territories) was not available yet. We compiled from the literature a list of naturalized alien vascular plant species with data on their occurrence in 33 Indian states, and related the richness of naturalized species per state to climate, socioeconomic parameters and human influence. In total, we report 471 naturalized species in India, which represents 2.6% of the total flora of this country, and for 449 of them we provide the distribution in the states. The highest and lowest numbers of naturalized species are reported from Tamil Nadu (332) and the island Lakshadweep (17), respectively. The families richest in naturalized species are Compositae (75), Leguminosae (60) and Poaceae (36). The highest numbers of naturalized aliens occurs in states located at lower latitudes in the tropics, and in more northernly located states that even in the dry period still have relatively high amounts of precipitation. Naturalized species richness of a state is furthermore positively related to socioeconomic factors represented by the percentage of the population living in urban areas, and human population density. The state-wise inventory of naturalized alien species improves our knowledge on threats associated with plant invasions in India, and can be used to provide arguments for promoting programs on conservation of native biodiversity in the country as well as in particular states.publishe